association	dataset	threshold value	standardized value
abnormality of the nail	HPO Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN1_02_79	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.24793
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.963941
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7317
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84845
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5854-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87154
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21934
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Birth Weight	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00371
dolichol-phosphate-mannose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19674
CACNG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17247
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83676
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9768
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62199
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.04015
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-S4Q7-0926-SM-4AD5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933194
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Harderian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
Chorion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35492
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1266
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48388
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Glioblastoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
bodies	GeneRIF Biological Term Annotations	1.0	null
palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.856905
CYP27C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77375
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6003
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
asthma	GWASdb SNP-Disease Associations	1.0	0.741413
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12719
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
cognitive impairment	HPO Gene-Disease Associations	1.0	null
SCLC22H	DepMap CRISPR Gene Dependency	1.0	2.9159
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13669
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45842
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
APCDD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0901
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17742
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.373
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04171
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07267
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38936
EFE184	CCLE Cell Line Gene Expression Profiles	1.0	1.3662
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32883
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50972
transport	GO Biological Process Annotations 2015	1.0	null
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881883
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62015
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888241
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947894
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53744
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33669
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE226285_2_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37747
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-1926-SM-4DXUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846157
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96872
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2052	DepMap CRISPR Gene Dependency	1.0	7.98229
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_5889_OE_myrAKT1_SRP193116	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45257
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2158
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16002
Bmi-1_KD_GDS2724_102_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11665
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53046
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03244
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
abnormal stratum corneum lipid matrix formation	MGI Mouse Phenotype Associations 2023	1.0	null
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91576
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77725
ETV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25027
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
hsa-miR-1226	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TGW	DepMap CRISPR Gene Dependency	1.0	2.57733
hsa-miR-485-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854125
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070009
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65156
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48169
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74556
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918143
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34692
HCC515	DepMap CRISPR Gene Dependency	1.0	4.18555
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04359
mode of inheritance	HPO Gene-Disease Associations	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0289
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6C-Table_S6C_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_PRAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6458
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836076
GSE193258,GSE193259_5_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Regular astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
PMC10274772-media-2.xlsx-TFAP2A_motif_in_enhancers-TFAP2A_target_genes_with_TFAP2A_motif_in_their_enhancer_region_n_99_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57415
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-125a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Aplasia/Hypoplasia Of The Eyebrow	DisGeNET Gene-Phenotype Associations	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875977
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62047
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80461
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9848
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91129
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240056
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915345
Megaconial type congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9615
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29029
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27615
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947466
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07369
PC3	CCLE Cell Line Gene CNV Profiles	1.0	2.4424
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07328
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03151
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91266
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34692
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
BRI3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59069
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ML-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70724
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CE-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart disease	GWASdb SNP-Disease Associations	1.0	0.169423
Keratitis	DisGeNET Gene-Disease Associations	1.0	null
PMC9038526-mmc1.xlsx-postCOVID_LPS_vs_healthy_L-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45373
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
Recurrent corneal erosion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
congestive heart failure	GWASdb SNP-Disease Associations	1.0	0.532414
H357	DepMap CRISPR Gene Dependency	1.0	2.50891
XPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95164
JUND	ENCODE Transcription Factor Targets	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35566
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11237048-41598_2024_64364_MOESM1_ESM.pdf-28-ENSG00000221818_EBF2	Rummagene Transcription Factor Associations 2026	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16904
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
JHESOAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50933
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430243
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1667
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893637
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MTIF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28026
five	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8634-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64904
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
hsa-miR-1297	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
HEATR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03876
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
individuals	GeneRIF Biological Term Annotations	1.0	null
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1784
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Exfoliative Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77732
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886064
GSE182840,GSE182844_0_v_1_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55317
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
tgm1	GeneRIF Biological Term Annotations	1.0	null
inflammatory abnormality of the skin	HPO Gene-Disease Associations	1.0	null
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28264
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02821
magnesium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51117
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	1.0	1.45575
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30613
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B6-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17222
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31399
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941606
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37062
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889435
ITM2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73008
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62465
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.048531
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37778
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.059
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90632
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE131649_4_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03619
CEBPZ_02_176	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921104
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03445
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.403
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887081
Perturb_7742_KD_NOLC1_SRP316009	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
congestive heart failure	GWASdb SNP-Phenotype Associations	1.0	0.45416
AZIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0888
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12123
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.3549
PMC12042558-12885_2025_14205_MOESM1_ESM.xlsx-Sheet1-Supplementary_file_2_Univariate_cox_regression_of_HOXB8-derived_molecules_HOXB8	Rummagene Transcription Factor Associations 2026	1.0	null
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33465
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34796
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
EZH2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hyperkeratosis	DisGeNET Gene-Disease Associations	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7834
CREB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9584
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053944
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.76073
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
respiratory tract infection	HPO Gene-Disease Associations	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4742
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.913498
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.915534
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.97338
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847121
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05336
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03949
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02657
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79498
providing	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3255
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29155
staining	GeneRIF Biological Term Annotations	1.0	null
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49789
layer	GeneRIF Biological Term Annotations	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
KO52	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683919
BF-02-AC35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341293
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19783
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1832
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
X-linked chondrodysplasia punctata 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.999
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19981
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	2.07793
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.882051
monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
AKT1_OE_GDS2308[_473_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	4.24468
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.441312
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20401
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40101
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7207
EMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87629
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18925
aplasia/hypoplasia of the eyebrow	HPO Gene-Disease Associations	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_23_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948079
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.54182
everted lower lip vermilion	HPO Gene-Disease Associations	1.0	null
CLPP_KO_GDS4791_537_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71355
ichthyosis, congenital, autosomal recessive 6	OMIM Gene-Disease Associations	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79516
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2064
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45469
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40002
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867183
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96685
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21465
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07526
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47528
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76846
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04573
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38131
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01752
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERRFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33874
nonsense	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911076
DMS114	CCLE Cell Line Gene Expression Profiles	-1.0	-2.68441
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54013
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SPI1	ENCODE Transcription Factor Targets	1.0	null
interact	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28727
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889747
Leukemia, Myeloid, Acute	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZFP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91196
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05992
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.844141
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89391
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3196
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53959
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49504
SUDHL5	DepMap CRISPR Gene Dependency	1.0	2.88984
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.05227
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75253
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31713
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58936
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.0672
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58757
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217144
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.760158
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93886
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41124
ELF1	ENCODE Transcription Factor Targets	1.0	null
cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.88286
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929629
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05031
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37001
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83409
GLB1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00366
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32684
methylphenidate_mus musculus_gpl11180_gse33619	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35538
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57026
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
Perturb_6027_KD_KHDRBS1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.3758
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.111
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28142
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17074
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041384
chr5_157476582_C_T_b38	GTEx eQTL 2025	1.0	2.06616
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20249
UMUC1	CCLE Cell Line Gene Expression Profiles	1.0	2.58056
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897852
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11659
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.354868
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.267
Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829195
ectropion	HPO Gene-Disease Associations	1.0	null
Blepharitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C80	DepMap CRISPR Gene Dependency	1.0	2.76021
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.06937
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50282
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62847
congenital ichthyosiform erythroderma	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15687_KO_Pten_SRP095406	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Autosomal recessive congenital ichthyosis 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
TPD52L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
recurrent infections	HPO Gene-Disease Associations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867664
Ectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.37584
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07993
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870692
PMC4429043-NIHMS635275-supplement-supplement_1.pdf-13-DLX3_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
LYPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06926
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30487
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44499
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.912072
DMS-273	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897065
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44801
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47334
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.178
GSE243491_3_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3664-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914949
Ichthyosiform Erythroderma, Congenital	DisGeNET Gene-Disease Associations	1.0	null
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07538
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53348
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967143
hsa-miR-1296	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.19738
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40595
RPMI8226	DepMap CRISPR Gene Dependency	1.0	2.82507
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0187
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92149
diffuse	GeneRIF Biological Term Annotations	1.0	null
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32765
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85091
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-221	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
Pruritus	DisGeNET Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63954
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.042
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22587
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.09493
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79854
Perturb_6073_KD_SUV39H1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.0432
hsa-let-7e	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851223
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	4.84301
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961772
SUZ12	ENCODE Transcription Factor Targets	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042812
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	2.4803
Epidermolysis bullosa dystrophica	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10441
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925385
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-let-7b	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862642
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.063865
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01574
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947894
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17782
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40374
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Agranular insular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24213
GSE250089_0_v_3_epcam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04517
PMC5971224__SF1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.396
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05232
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43042
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Meningioma	HuGE Navigator Gene-Phenotype Associations	1.0	null
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18651
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05929
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06145
MAX	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1269	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76532
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72456
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57994
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393819
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.15256
hsa-miR-3646	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07529
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69716
EC-89-AJ93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220753
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45101
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7971
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25609
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00122
Sjogren-Larsson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11627
MARVELD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19434
SLC2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47509
abnormality of the lip	HPO Gene-Disease Associations	1.0	null
Bacteroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
USPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86245
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824434
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88511
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WQ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.048705
ES4	DepMap CRISPR Gene Dependency	1.0	2.43355
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09495
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89137
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06801
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10093
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLPP_KO_GDS4791_374_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal recessive congenital ichthyosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.023
eclabion	HPO Gene-Disease Associations	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833714
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMRC2	CCLE Cell Line Gene CNV Profiles	1.0	1.59443
hsa-miR-125b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17288
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23963
STAT3	ENCODE Transcription Factor Targets	1.0	null
keratins	GeneRIF Biological Term Annotations	1.0	null
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10318
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0542
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36178
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31585
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833522
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0336
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23316
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97587
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14592
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04635
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE226285_2_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-339-RARA_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80085
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4432
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.51229
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60152
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14836
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.598
KIFBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42997
Perturb_6040_KD_MRTO4_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.2832
MAPK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4306
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
GAS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99003
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874085
H2BK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dendritic shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19482
abnormality of the pinna	HPO Gene-Disease Associations	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
ARH-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80962
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7016
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24354
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.867
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03483
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31552
BICR16	DepMap CRISPR Gene Dependency	1.0	5.91654
Lung squamous cell carcinoma_LUSC_TCGA-34-5236-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF652	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6609
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acanthosis	DisGeNET Gene-Phenotype Associations	1.0	null
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46468
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19334
Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27277
kidney disease	GWASdb SNP-Disease Associations	1.0	1.25886
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22745
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20954
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03024
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392041
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26377
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32992
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16196
Peeling skin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X-linked lymphoproliferative syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Lung adenocarcinoma_LUAD_TCGA-05-4250-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S3.xlsx-Top_PrEC_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
Keratohyalin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.166
three	GeneRIF Biological Term Annotations	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16954
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7756
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28153
SNUC2A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93682
WIL2-NS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	1.87537
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29002
Ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.893
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Focal nonepidermolytic palmoplantar keratoderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.917
SSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65482
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCC4	DepMap CRISPR Gene Dependency	1.0	3.48513
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28008
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74966
USF2	ENCODE Transcription Factor Targets	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286186
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50466
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871299
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064646
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03658
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Holocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02892
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.43967
Spinalcord	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13186
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101845
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.670064
placenta	HPA Tissue Protein Expression Profiles	1.0	0.844141
Anal sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20233
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65776
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42455
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08462
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35134
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889242
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8203
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.930152
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59951
TXNDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9638
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45704
receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046616
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
affecting	GeneRIF Biological Term Annotations	1.0	null
chr5_157463889_C_G_b38	GTEx eQTL 2025	1.0	1.12313
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236923
ASXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23051
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34989
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.921736
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.2917
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	1.22705
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02993
Nail Abnormality	DisGeNET Gene-Phenotype Associations	1.0	null
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87197
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.192278
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16896
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3038
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.0866
Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12753
kidney_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89827
GSE239844_8_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64428
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95274
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32394
coronin-1A deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40616
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
HCC78	DepMap CRISPR Gene Dependency	1.0	3.00571
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19974
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.988114
YTHDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65009
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1321	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
impaired skin barrier function	MGI Mouse Phenotype Associations 2023	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
Leukemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50918
Parakeratosis	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311637
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05633
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859567
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.05786
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
1321N1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58866
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59567
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16188
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34527
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4868-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5970-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11079
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3713
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118077_1_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chanarin-Dorfman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78767
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99654
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5311_KD_NFATC3_SRP275579	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
hsa-miR-4500	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
Anhidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.967
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54919
GTEX-TKQ1-0526-SM-4DXTG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946012
hsa-miR-4329	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98392
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26947
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877944
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3447
SNU1214	CCLE Cell Line Gene Expression Profiles	1.0	2.15706
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75942
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54926
genotypephenotype	GeneRIF Biological Term Annotations	1.0	null
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86186
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00811
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245594
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.330372
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
epidermal thickening	HPO Gene-Disease Associations	1.0	null
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PD-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36057
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42517
hsa-miR-26a	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Acrokeratosis verruciformis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11563
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04833
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17264
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41945
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
increased sphingosine level	MGI Mouse Phenotype Associations 2023	1.0	null
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854951
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96098
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.014
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215086_1_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inflammatory abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.051
Lamellar ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1406
PMC6433273-pone.0214296.s009.xlsx-Table_C-S3_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_6_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal	GeneRIF Biological Term Annotations	1.0	null
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02629
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03347
NA-16-OJ70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256807
barrier	GeneRIF Biological Term Annotations	1.0	null
DVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84468
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80959
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054678
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42173
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3517
autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
Perturb_5605_KD|OE_METTL1|RPTOR_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Corolla tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
GSE156978_1_v_0_dnmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16001_KO_TP53_SRP261893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.827
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61713
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53975
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3926	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885251
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860477
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20139
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18733
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45798
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.53
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7715
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26622
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924192
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203382
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00983
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43923
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.06
recurrent	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34192
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89388
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX4-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4725-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_27_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Miscellaneous transport and binding events	Reactome Pathways 2024	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41251
heart failure	GAD Gene-Disease Associations	1.0	null
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13286
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5895
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87175
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	9.89591
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ichthyosis	HPO Gene-Disease Associations	1.0	null
Bullous congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
ZNF528	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60452
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11959
PMC9927941-jci-133-163612-s046.xlsx-Sheet1-Table_S12_PAX5_expression_correlates_p_0_05_with_expression_of_126_of_the_other_T2D_DEGs_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Vohwinkel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57462
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217634
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9418
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64567
Autosomal recessive congenital ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
NCIH1666	CCLE Cell Line Gene Expression Profiles	1.0	2.36633
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213588
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.827
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal magnesium ion homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873462
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08408
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00767
B cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
Tegmental reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09674
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47439
ATXN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86719
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17455
Perturb_15480_OE_ERG_SRP075246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.6778
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68143
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7i	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
cone-rod dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160053
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97465
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dry skin	HPO Gene-Disease Associations	1.0	null
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
AXIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39929
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65677
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8314
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69346
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985492
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09518
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.95153
keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.560227
recurrent respiratory infections	HPO Gene-Disease Associations	1.0	null
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04543
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89667
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40155
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052527
mitochondrion-associated adherens complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.27
abnormal corneocyte morphology	MGI Mouse Phenotype Associations 2023	1.0	null
SW780	CCLE Cell Line Gene Expression Profiles	1.0	1.77027
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1205
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87226
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871299
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.7504
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62106
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74859
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCAPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33995
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32502
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF280B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68408
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.062985
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33863
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51814
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69601
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	2.05014
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71788
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9246
FARAGE	DepMap CRISPR Gene Dependency	1.0	3.05746
AC-55-XA97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204051
Ainhum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76725
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27133
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8805
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KS1	CCLE Cell Line Gene Expression Profiles	1.0	1.38975
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09392
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910052
hsa-let-7d	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
CD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49011
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36754
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20746
NCIH747	DepMap CRISPR Gene Dependency	1.0	2.56229
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890625
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
CLPP_KO_GDS4791_107_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_4177_KO_Dnmt1_SRP043000	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intensity	GeneRIF Biological Term Annotations	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0667
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96502
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pseudoxanthoma elasticum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
hsa-miR-635	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67365
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DLX5_KO_GSE22381_5_mouse_ear (otic vesicle)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911791
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85943
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.483457
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
epidermis	GeneRIF Biological Term Annotations	1.0	null
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57832
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.067
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37152
Dry Skin	DisGeNET Gene-Phenotype Associations	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76897
functional respiratory abnormality	GWASdb SNP-Phenotype Associations	1.0	0.640327
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51053
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03767
Perturb_8709_OE_SMAD4_SRP255626	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Hyperkeratosis	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal keratinocyte differentiation	MGI Mouse Phenotype Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lipid	GeneRIF Biological Term Annotations	1.0	null
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.371
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917618
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929047
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34399
granular	GeneRIF Biological Term Annotations	1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.65
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835681
PMC8511326__F4	PFOCR Pathway Figure Associations 2024	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825064
all	HPO Gene-Disease Associations	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01019
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	0.844141
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23779
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34728
UNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75456
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47305
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69006
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49196
LB-65-SM65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284346
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05659
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_109_KD_FOXC1_SRP276213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
one	GeneRIF Biological Term Annotations	1.0	null
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.93919
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22114
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2516
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32654
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063998
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3-21867929-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4734-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01636
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.988957
SUZ12	ChEA Transcription Factor Targets	1.0	null
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.834637
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78319
abnormality of skin physiology	HPO Gene-Disease Associations	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Hemophagocytic lymphohistiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00083
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48033
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05725
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22751
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.031
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1306
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82215
UD-07-US73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3848
BICR31	CCLE Cell Line Gene Expression Profiles	1.0	1.63292
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
PC-18-VX23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220442
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80728
Vesiculobullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.9903
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19598
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
missense	GeneRIF Biological Term Annotations	1.0	null
ichthyosis	GeneRIF Biological Term Annotations	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8688
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormal elasticity of skin	HPO Gene-Disease Associations	1.0	null
Oligosaccharyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.567
Lamellar body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.111
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
S0-EE-XKW4_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269528
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14166
hsa-miR-27b	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
H4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.51757
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08361
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0402
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953025
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20021
metabolism	GeneRIF Biological Term Annotations	1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28459
PMC7780220-12943_2020_1301_MOESM8_ESM.xlsx-Fig_3A_RNA-seq_DEGs-Summary_701_LPS-induced_DEGs_361_THZ1-sensitive_DEGs_in_blue_of_macrophages_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
KIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78909
ZNF100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91008
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93931
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65575
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55682
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10367
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37696
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66637
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0208
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952417
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89099
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Perturb_14503_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.7626
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3763
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26964
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201025
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59562
abnormality of the helix	HPO Gene-Disease Associations	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.481
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
indicative	GeneRIF Biological Term Annotations	1.0	null
Cicatricial ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
Ichthyosis vulgaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.407
Secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.808
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
membrane part	GO Cellular Component Annotations 2015	1.0	null
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3693
ICC106	DepMap CRISPR Gene Dependency	1.0	2.02058
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4235
ALDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952417
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3912
PRDM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17615
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863265
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886227
decreased sphingosine level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
SLC27A4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12582
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.87313
abnormality of the eyebrow	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36399
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE207471_2_v_0_btla_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12662
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-513a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EM-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45409
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25032
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-128	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63409
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34494
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04144
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842388
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.104
metal ion transport	GO Biological Process Annotations 2023	1.0	null
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95702
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
EP300	ENCODE Transcription Factor Targets	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51518
Keratosis follicularis spinulosa decalvans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22384
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75776
ITK_knockout_241_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63031
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2132
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dehydration	DisGeNET Gene-Phenotype Associations	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
congenital	GeneRIF Biological Term Annotations	1.0	null
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF626	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07412
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89634
ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 6	CTD Gene-Disease Associations	1.0	2.88009
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17194
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90323
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.94643
SF1_01_271	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.06879
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55384
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50192
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09201
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.867
abnormality of skin adnexa	HPO Gene-Disease Associations	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87669
Perturb_5312_KD_PPP3CC_SRP275579	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270506
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1988
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8042-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
magnesium ion transport	GO Biological Process Annotations 2015	1.0	null
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06379
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80393
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886258
Gangrene	DisGeNET Gene-Disease Associations	1.0	null
A375SKINCJ1	DepMap CRISPR Gene Dependency	1.0	2.67003
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2332
lateral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41132
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoproliferative syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14813
A_CA_04_2009_4dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.09005
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35241
PMC9692021-Table_4.xlsx-Table_S4-Table_S4_405_DEGs_of_RA_synovial_tissues_between_NFIL3-high_and_NFIL3-low_group_NFIL3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01675
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33015
KNS62	CCLE Cell Line Gene Expression Profiles	1.0	1.54087
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903584
Chorionic villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	1.10276
PMC11237048-41598_2024_64364_MOESM1_ESM.pdf-28-EBF2_EBF2	Rummagene Transcription Factor Associations 2026	1.0	null
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
STAT3	ChEA Transcription Factor Targets	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31481
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14197
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06438
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931434
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
esophagus	HPA Tissue Gene Expression Profiles	1.0	0.943
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.4612
CLPP_KO_GSE40207_392_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE151612_4_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.445672
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833714
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63493
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61111
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.83695
CREB1	ENCODE Transcription Factor Targets	1.0	null
ST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93631
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885794
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17239
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Heart Failure	dbGAP Gene-Trait Associations	1.0	0.009478
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42173
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040722
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8742
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Autosomal recessive congenital ichthyosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12788
eomes_23431145_e14dot5_neocortex_lof_mouse_gpl6246_gse43387	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.449356
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67324
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97479
Ray floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950368
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20211
maintaining	GeneRIF Biological Term Annotations	1.0	null
Glioma	HuGE Navigator Gene-Phenotype Associations	1.0	null
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207944
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.257301
abnormal keratohyalin granule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830645
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NUDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88885
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72879
Autosomal recessive congenital ichthyosis 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
retinoid	GeneRIF Biological Term Annotations	1.0	null
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
MRPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93638
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05167
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94687
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02297
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.10729
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08925
Perturb_2991_KO_TP53_SRP287851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.56039
TMEM141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04239
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06673
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90268
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
Perturb_9077_KD_SRSF7_SRP365961	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29974
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03728
epidermal	GeneRIF Biological Term Annotations	1.0	null
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.479014
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.383
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18715
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.58251
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12413
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94197
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0458
TP63	ChEA Transcription Factor Targets	1.0	null
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52728
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17999
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.776079
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84845
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253267
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48681
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81917
Perturb_8930_KD_ELL_SRP275788	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20744
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.126
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25603
hsa-miR-26b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55456
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.488
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05606
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03445
Lymphoproliferative syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
Ectropion	DisGeNET Gene-Disease Associations	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02024
hsa-miR-1265	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
TMEM69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57438
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28371
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34979
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55118
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68834
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966745
Lack Of Skin Elasticity	DisGeNET Gene-Phenotype Associations	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18148
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77213
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27742
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892143
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043466
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.693311
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0667
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56142
PMC12482102-10020_2025_1363_MOESM7_ESM.xlsx-CASC19_KD_DEG-ENSEMBLE_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05774
hsa-miR-4756-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CG-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065117
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917029
hsa-miR-3913-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mildly	GeneRIF Biological Term Annotations	1.0	null
Factor VII deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1965
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital Nonbullous Ichthyosiform Erythroderma	DisGeNET Gene-Disease Associations	1.0	null
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59162
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
Perturb_6026_KD_KAP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.68221
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45171
X-linked lymphoproliferative syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1084
CTCF	ENCODE Transcription Factor Targets	1.0	null
divalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
magnesium ion transport	GO Biological Process Annotations 2025	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.2092
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
correlation	GeneRIF Biological Term Annotations	1.0	null
Acrodysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
PMC12482102-10020_2025_1363_MOESM7_ESM.xlsx-CASC19_KD_DEG-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.72057
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959233
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RB-34-TO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241777
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71355
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
ZNF263	ENCODE Transcription Factor Targets	1.0	null
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.824036
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15384
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.25338
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28815
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
metal ion transport	GO Biological Process Annotations 2025	1.0	null
SPDEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.08358
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87546
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61508
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
gangrene	HPO Gene-Disease Associations	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93165
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
X-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.612
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385326
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58979
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04598
chronic obstructive pulmonary disease	GWASdb SNP-Disease Associations	1.0	0.741413
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16411
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
ZNF394	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49514
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRG1_DEPLETION_GDS2156_720_mouse_Embryos (maternally depleted)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75208
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01066
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00208
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50052
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39957
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.656
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17114
U343	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60058
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30462
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34668
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87596
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
RELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61542
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836503
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PSN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3342
hsa-miR-4450	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM115	DepMap CRISPR Gene Dependency	1.0	3.45823
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65086
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988381
hsa-miR-3202	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46169
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043253
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5263
PMC11747033-Table1.xlsx-Sup_Table_S1-IFNy_LPS_TREATED_HMEC_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56599
Perturb_7847_KD_PUM2_SRP166185	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.1593
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4465	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00734
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.622
Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99853
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S7-Supplementary_Table_S7_Four_cluster_profiles_using_short_time-series_expression_miner_STEM_algorithm_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43521
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48813
RXRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.278
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27181
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10643
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25846
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78363
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AKT1_knockout_210_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.38865
G3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33874
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51418
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25207
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05701
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13356
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974002
GTEX-XUZC-1226-SM-4BRVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92789
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25735
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84951
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11025
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40588
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17568
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41033
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dehydration	HPO Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8415-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30067
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08981
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24568
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5324
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5636
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUV39H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78883
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20674
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16608
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871299
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080606
elox3	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
Keratoderma	DisGeNET Gene-Disease Associations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.203
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.44408
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992604
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53425
Abnormality Of The Dentition	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE150557_1_v_0_dnmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.844141
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16546
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947404
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.884674
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
RT112	CCLE Cell Line Gene Expression Profiles	1.0	1.971
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34244
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
vagina	GTEx Tissue Gene Expression Profiles	1.0	0.896584
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871299
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97736
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83059
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34878
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85933
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.950631
disease	GWASdb SNP-Disease Associations	1.0	0.036421
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXD4L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30813
PMC5842026-mmc5.xlsx-HIC1_directTargets_48h-Gene_symbol_HIC1	Rummagene Transcription Factor Associations 2026	1.0	null
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-4755-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37702
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22204
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06977
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126311
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93095
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13899
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200253
NK cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69346
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01951
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68875
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6471
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9685
Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHILD syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A1HS-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
HS616T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82189
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40399
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88531
MYOG	ENCODE Transcription Factor Targets	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13994
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
abnormality of the head	HPO Gene-Disease Associations	1.0	null
JD-62-TK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293162
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51615
abnormality of immune system physiology	HPO Gene-Disease Associations	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3907
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.146
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73913
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17532
hsa-miR-765	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
GAL3ST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20009
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887545
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060277
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857485
Chondrodysplasia punctata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
NCIN87	CCLE Cell Line Gene Expression Profiles	1.0	1.85471
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954406
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60581
Sarcoma_SARC_TCGA-X9-A971-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27317
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.08283
molecular_function	GO Molecular Function Annotations 2015	1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37747
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0241
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65082
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1767
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57249
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67787
hsa-miR-4732-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21716
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ichthyosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14968
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885098
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13055
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4024
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953285
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210474
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7969
Selective immunoglobulin deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
hacat	HPA Cell Line Gene Expression Profiles	1.0	0.876326
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845627
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08108
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	1.57475
H4C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54457
CSNK1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37585
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33247
PMC10769395-media-2.xlsx-S2D_EF_Repressed_genes-Ebegboni_et_al_Supplemental_Table_S2D_Increased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969297
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45414
GSE242199_2_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CALU1	DepMap CRISPR Gene Dependency	1.0	2.89707
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30029
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09469
SLC17A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11859
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8595
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25773
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28727
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95495
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53637
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02629
Perturb_4556_KD_Ncor2_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.80603
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44702
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91596
RNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.019
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53727
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27968
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2326
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10282
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rhoptry neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40767
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58421
ARMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18335
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.896
RAB3GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58578
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28544
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0331
hsa-miR-211	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Skin disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937368
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9328
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844191
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17782
TMEM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66486
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.642
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3688
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41178
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00463
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12509
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
abnormal hair quantity	HPO Gene-Disease Associations	1.0	null
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17547
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Hypohidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.318
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833714
Sarcoma_SARC_TCGA-DX-A3UF-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70886
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16563
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54551
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56899
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156342
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5379
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242805
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32542
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21028
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF12_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203553
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1436
Perturb_8702_KD_MXD4_SRP374659	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.55824
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29212
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928204
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
decreased birth weight	MGI Mouse Phenotype Associations 2023	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86597
Primary hypomagnesemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993143
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
BICR16	CCLE Cell Line Gene Expression Profiles	1.0	1.76375
chr5_157448126_C_T_b38	GTEx eQTL 2025	1.0	1.26054
pruritus	HPO Gene-Disease Associations	1.0	null
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.591812
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.91308
Joubert syndrome 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37585
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.52707
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36834
UBTF	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23146
lipoxygenases	GeneRIF Biological Term Annotations	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1282
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.427
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.81957
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59519
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7423-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08366
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3532
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46041
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22318
GTEX-XAJ8-0926-SM-47JXZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
B cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93464
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
hsa-miR-3663-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
ZB-29-GC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238181
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967658
ASB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42224
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
hsa-miR-766	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890898
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87128
GTEX-PLZ4-2826-SM-3P617	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0036
easily	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
decreased ceramide level	MGI Mouse Phenotype Associations 2023	1.0	null
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27317
Hereditary spastic paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
DU145	DepMap CRISPR Gene Dependency	1.0	2.27738
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145215_2_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8711_OE_SMAD4_SRP255626	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858113
CAOV4	DepMap CRISPR Gene Dependency	1.0	3.08958
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4002
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251619
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3125
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3785
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19458
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.92806
chr5_157391295_T_A_b38	GTEx eQTL 2025	1.0	1.03918
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
Perturb_6025_KD_KAP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.07899
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825269
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08708
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
Familial woolly hair syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16376
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2837
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lower dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77613
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121879
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965574
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75083
CLPP_KO_GDS4791_104_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22694
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.96822
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VL-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLIN5_OE_GSE44192_482_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
C2orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9282
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30483
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34813
nucleus subceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951823
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4217
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glutamate decarboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14098
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09823
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1993
OAW42	DepMap CRISPR Gene Dependency	1.0	2.51654
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44556
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22751
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
GSE77795_0_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824917
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02931
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6321
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
18406887-Table5	GeneSigDB Published Gene Signatures	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal recessive congenital ichthyosis 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
LS-1034	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10623
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5243
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11612
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	1.76341
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6FZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
Brain Lower Grade Glioma_LGG_TCGA-DB-A64V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr5_157333000_A_T_b38	GTEx eQTL 2025	1.0	3.17646
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-Symbol_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C9orf72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85933
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4586
Perturb_13243_KD_Lnc956_SRP345092	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE122711_2_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937377
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125219,GSE125221_5_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE125153_2_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5213
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0428
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
A549	CCLE Cell Line Gene Expression Profiles	1.0	1.51384
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72399
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.46413
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835425
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10088
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37036
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14338
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2296
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6997
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.986683
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41904
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.223
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063966
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.907454
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16442_KD_IL13RA2_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2433
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68712
MEIOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14226
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
chromosome	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923059
Autosomal recessive congenital ichthyosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Infectious mononucleosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32379
Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
FMNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33753
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02709
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16904
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64087
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74553
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37801
juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631931
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10194
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.935291
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69662
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
Disc floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LN382	DepMap CRISPR Gene Dependency	1.0	2.43504
LBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52327
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9605
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.74791
PPP2R1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12815
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
GSE242199_2_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0324
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4526
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65391
hsa-miR-4715-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55615
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11402
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37482
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7427
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31326
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.538347
abnormal skin appearance	MGI Mouse Phenotype Associations 2023	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281734
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87493
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11917
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2982_KO_TP53_SRP287851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.32203
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cargo receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
Signal recognition particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.058
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18985
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91111
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058427
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53728
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21302
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903499
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942654
PMC11811202-41598_2025_89390_MOESM1_ESM.pdf-11-ZNF274_ZNF274	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hearing impairment	HPO Gene-Disease Associations	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4644
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2335
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.44866
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A463-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MITD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84647
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37548
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05361
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12584
TPBGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26607
gigantocellular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886324
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lamellar	GeneRIF Biological Term Annotations	1.0	null
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21302
Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
EBV-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45755
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.603
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98114
ZNF705B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89438
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951285
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10896
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8946
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886935
thickened skin	HPO Gene-Disease Associations	1.0	null
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859284
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41633
GSE67266_5_v_1_etoposide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18793
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842955
hsa-miR-4324	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50055
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51418
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
GTPBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
HL60	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24735
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18399
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15804
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14787
Dysgammaglobulinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
bmp receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.221025
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069929
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17591
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0915
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18054
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215086_5_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84745
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ebolavirus(ZEBOV)_3day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31007
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94492
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043734
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57479
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57609
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.417
mantle zone of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04868
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952101
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16912
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64138
Molluscum contagiosum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73732
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
MNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39309
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946285
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84902
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978643
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200654
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53864
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95677
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12471
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6109
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96452
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40557
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19439
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19101
PROB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65775
Perturb_6061_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.46689
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843466
SCC15	CCLE Cell Line Gene Expression Profiles	1.0	1.49966
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6223-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hereditary spastic paraplegia 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MGAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5328
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18929
corneal erosion	HPO Gene-Disease Associations	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC316	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77031
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	469.286
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE210667_3_v_2_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80321
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21211
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38866
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35455
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
hsa-miR-4727-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09036
Sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.4122
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0708
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7c	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
Perturb_16441_KD_IL13RA1_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.5563
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95359
Perturb_9004_KD_C19orf12_SRP212737	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.9314
WM115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82611
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01279
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	10.9985
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10367
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SOX17	ChEA Transcription Factor Targets	1.0	null
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
hsa-miR-4474-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40682
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.443292
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907548
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60218
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR7-List_of_differentially_expressed_genes_in_AR11_vs_AR7_Negative_value_means_down-regulation_in_AR11_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GALK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31622
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10606
ZNF143_02_59	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.0
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842317
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0512
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8929
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.048
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48101
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35492
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
YD10B	CCLE Cell Line Gene Expression Profiles	1.0	1.51054
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70038
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0726
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased keratohyalin granule size	MGI Mouse Phenotype Associations 2023	1.0	null
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56982
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830072
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
upper basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75667
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00859
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37033
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841675
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68515
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06154
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966113
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.516
Vibrissal follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
single-organism transport	GO Biological Process Annotations 2015	1.0	null
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63828
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0095
Pachyonychia congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
BronchialEpithelialCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.24742
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10512
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
T cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22409
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chr5_157384435_G_A_b38	GTEx eQTL 2025	1.0	2.30845
hsa-miR-4508	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
specific	GeneRIF Biological Term Annotations	1.0	null
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974354
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08167
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05737
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920218
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.922564
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73629
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27982
RCOR3	ChEA Transcription Factor Targets	1.0	null
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873393
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53354
RNF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69054
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75101
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59491
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34527
ion transport	GO Biological Process Annotations 2015	1.0	null
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31537
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
erythroderma	HPO Gene-Disease Associations	1.0	null
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339375
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864929
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7448
JMJD1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01058
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78738
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37869
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44981
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51331
RNF2	ChEA Transcription Factor Targets	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1616
PMC11193738-41467_2024_48647_MOESM8_ESM.xlsx-Data_S5-Data_S5_HNF4A-bound_gene_targets_identified_from_ChIP-Seq_in_hepatic_cells_D8_Hep_and_HepG2_cells_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67F-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03292
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60605
FOS	ENCODE Transcription Factor Targets	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45608
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.225
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.928208
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79434
hypohidrosis or hyperhidrosis	HPO Gene-Disease Associations	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8643
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937368
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79513
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
parakeratosis	HPO Gene-Disease Associations	1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1892
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74867
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0928
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08719
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65165
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	0.990391
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5192
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MT-ATP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8797
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32051
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88926
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56207
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62591
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91054
keratoderma	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041081
Autosomal recessive congenital ichthyosis 6	ClinVar Gene-Phenotype Associations	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
GSE195559_3_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UG-01A-32R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08547
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20115
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51586
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37288
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73519
GSE201217_2_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222753
Perturb_10228_KO_Nfat5_SRP337224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.98213
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65762
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26497
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.69767
TFPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56228
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31713
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autosomal Recessive Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9641
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937731
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846363
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Perturb_6060_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
increased ceramide level	MGI Mouse Phenotype Associations 2023	1.0	null
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27577
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9696
ARL2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67186
Agranular insular area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41415
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Perturb_14601_KO_ASAP2_SRP258574	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
abnormality of the face	HPO Gene-Disease Associations	1.0	null
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
growth delay	HPO Gene-Disease Associations	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.844141
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40252
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1226-SM-4AD4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16222
normal	GeneRIF Biological Term Annotations	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886403
ARC syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESS1	DepMap CRISPR Gene Dependency	1.0	2.36116
AM38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69882
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33595
SLC27A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77792
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
all	GWASdb SNP-Phenotype Associations	1.0	0.033437
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3130-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853959
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7672
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
GSE129858,GSE129859_1_v_3_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33249
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889077
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55992
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04086
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10189
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.709
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53644
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97157
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47822
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0885
BHLHE23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35739
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921211
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4576
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12734
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01917
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.62473
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23891
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6218-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273985
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13087
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153189_1_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7619
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850524
KNS42	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1944
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928399
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22812
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5009
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9079
hsa-miR-222	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4249
GSE215086_4_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17726
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980508
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10968
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
HSD3B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27286
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BMP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.096
hsa-miR-3915	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
DLX5_Deficiency_GDS4443_355_mouse_E10 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95694
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Perturb_6087_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.84581
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881118
Integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
ESO26	DepMap CRISPR Gene Dependency	1.0	3.27294
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069182
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66951
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01455
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31512
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-0.96576
RAB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61188
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64765
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26042
ATF3	ChEA Transcription Factor Targets	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4897
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54791
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68385
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0681
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438992
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9414
Netherton syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.258
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5155
GSE116242_0_v_1_olig2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25252
PMC11328671-jitc-12-4-s003.pdf-281-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal insufficiency	HPO Gene-Disease Associations	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859909
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32535
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49187
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00536
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03138
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4119
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01826
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6995-01A-31R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
processing	GeneRIF Biological Term Annotations	1.0	null
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29305
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03036
Eversion Of Lower Lip	DisGeNET Gene-Phenotype Associations	1.0	null
BE-31-XV38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224185
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.065
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79443
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SW872	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
Perturb_8954_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.699
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97073
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283513
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
BICR22	CCLE Cell Line Gene Expression Profiles	1.0	2.2806
Hypothalamic medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06894
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
PMC11329632-41419_2024_6969_MOESM3_ESM.pdf-97-ZBTB45_ZBTB45	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58789
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86602
Dry Skin, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
Immunodeficiency 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50052
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920432
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
abnormality of fluid regulation	HPO Gene-Disease Associations	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8185
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36877
Chromosome 15q11.2 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Congenital disorder of glycosylation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
GPR143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07136
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10011
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89972
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76485
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42194
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EZ-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36109
Epidermolytic hyperkeratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.483
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52683
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58657
liarozole	GeneRIF Biological Term Annotations	1.0	null
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7711
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
MT-ND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69415
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12083
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02179
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1196	DepMap CRISPR Gene Dependency	1.0	2.21127
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00321
abnormal epidermis stratum granulosum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4215
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884381
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14529
BE2M17	DepMap CRISPR Gene Dependency	1.0	3.42181
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
Autosomal recessive congenital ichthyosis 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27033
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.033513
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844689
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16954
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03411
Epstein-Barr virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938016
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864623
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885251
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00263
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
Hypotrichosis	DisGeNET Gene-Disease Associations	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.82914
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872969
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chr5_157371918_GTTATCATATAGTGGGAATAA_G_b38	GTEx eQTL 2025	1.0	2.89942
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
APLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04737
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271612
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03359
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-GeneID_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40991
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.90658
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38927
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.40657
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29043
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01453
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27836
RNF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854039
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA-SKI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15955
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950775
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00132
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929177
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79211
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09754
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3278
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.819
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95975
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7521
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16439_KD_IL13RA1_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
hsa-miR-3974	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38637
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15166
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6045
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF_02_56	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
hsa-miR-3657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA2_156_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95592
GSE215086_8_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95024
GPAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39925
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8495
CLASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58445
RT11284	CCLE Cell Line Gene Expression Profiles	1.0	1.74752
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20292
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.37572
abnormality of corneal epithelium	HPO Gene-Disease Associations	1.0	null
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24522
SERPINB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92333
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
palmoplantar keratoderma	HPO Gene-Disease Associations	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05031
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24547
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37287
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.501
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of skin morphology	HPO Gene-Disease Associations	1.0	null
MECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30218
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4801
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20657
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5781
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22873
Verruciform xanthoma of skin	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98689
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88604
SERPINB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19324
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216858
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267
NCI-H125 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
XRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65371
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20021
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16251
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.7284
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053122
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896652
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.35374
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23841
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040378
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06588
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23198
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4268	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.71958
Combined T cell and B cell immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.205
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19875
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
GSE232261,GSE232263_0_v_1_usf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60207
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44319
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97369
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3180-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06758
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229874
hsa-miR-504	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
bronchial disease	GWASdb SNP-Disease Associations	1.0	0.741413
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956274
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88505
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28904
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898527
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62019
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.74708
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6813882-NIHMS1526297-supplement-2.pdf-22-NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01547
PMC4330385-supp_gkv024_nar-03005-x-2014-File010.pdf-58-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90663
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03516
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78726
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive congenital ichthyosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.32687
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
ACCMESO1	CCLE Cell Line Gene CNV Profiles	1.0	1.58907
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92609
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58713
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46979
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888003
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MR-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
GAMG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63847
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LAMTOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51372
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.035
short stature	HPO Gene-Disease Associations	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16954
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16954
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40681
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09756
Brain Lower Grade Glioma_LGG_TCGA-HT-7467-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
USP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71062
GCT	CCLE Cell Line Gene CNV Profiles	1.0	1.56332
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892437
Perturb_12048_KO_LSD1_SRP310135	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.5421
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43074
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963983
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1304	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850327
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
hsa-miR-4261	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
hereditary spastic paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.804026
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5093
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955777
Perturb_4741_KD_Mettl3_SRP354177	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958521
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33597
Paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17658
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2111
HOXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83705
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50275
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
fatp4	GeneRIF Biological Term Annotations	1.0	null
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55735
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8574
transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
Sarcoma_SARC_TCGA-HB-A5W3-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.1956
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.499758
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nonepidermolytic palmoplantar keratoderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0184
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_31_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the hair	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37693
times	GeneRIF Biological Term Annotations	1.0	null
Corneal Erosion	DisGeNET Gene-Disease Associations	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.031
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
USF1_02_26	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive congenital ichthyosis 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.129
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84069
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23394
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843097
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3295
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5276-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6291
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0159
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07971
homozygous	GeneRIF Biological Term Annotations	1.0	null
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43442
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7037
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.55882
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.874506
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27678
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.14946
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29522
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41415
establishment of localization	GO Biological Process Annotations 2015	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15799
COR-L311	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	279.814
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961117
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4831
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59656
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60777
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96786
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.74641
PMC12445658-szaf036_supplementary_data.pdf-3-ELF3_ELF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847539
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18335
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78769
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834072
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6657958-pgen.1008250.s015.xlsx-ETS1_siRNA-Unnamed_0_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-98	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33327
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53292
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958403
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17673_OE_PGRA_SRP252069	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.11561
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881454
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01177
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329343
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6026
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78605
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66346
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20444
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96322
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053331
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866086
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
BCL3	ENCODE Transcription Factor Targets	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26515
abnormal epidermal lamellar body morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NCIH661	DepMap CRISPR Gene Dependency	1.0	3.6399
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34607
intermediate stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00874
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18596
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93276
NB6	DepMap CRISPR Gene Dependency	1.0	2.31983
YD38	DepMap CRISPR Gene Dependency	1.0	2.01211
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.34789
CORL51	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72875
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91066
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06858
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.204039
arthrogryposis, renal dysfunction, and cholestasis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
Prostate adenocarcinoma_PRAD_TCGA-HI-7170-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942035
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08462
hsa-let-7g	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25004
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.975225
CHD1	ENCODE Transcription Factor Targets	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ES5	DepMap CRISPR Gene Dependency	1.0	3.17208
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PRKAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18095
Hair follicle epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19439
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10034
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
Childhood absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92122
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97542
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967752
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94421
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13021
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92633
CALM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98828
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
Subiculum, ventral part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32654
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886258
QA-81-IM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282103
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36247
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77756
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.328332
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74853
hsa-miR-1324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63707
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77096
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66103
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
GSE167886_3_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.051
TDG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49276
abnormality of the teeth	HPO Gene-Disease Associations	1.0	null
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
hyperkeratosis	HPO Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88806
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4579
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.349
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0339
METTL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93219
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74806
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51433
GSE146982_3_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5614
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7687
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886258
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959829
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64832
AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886258
hsa-miR-33b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GSE89018_11_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Recurrent Respiratory Infections	DisGeNET Gene-Phenotype Associations	1.0	null
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55396
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04113
Immunodeficiency 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.94111
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909914
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98839
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.78069
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5353
GSE67266_5_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967037
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30982
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965587
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_01_164	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61095
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71765
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.83168
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48521
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25771
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060777
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57241
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47128
SNU1196	CCLE Cell Line Gene Expression Profiles	1.0	1.63794
otitis media	HPO Gene-Disease Associations	1.0	null
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45212
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.99812
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33029
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12595
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03389
BA-28-XM73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229821
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247572
HINFP_02_36	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.24793
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03774
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6995
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28595
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868266
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09376
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05568
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79989
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GJ-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63665
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PX-01A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.0651
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82469
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01203
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14510_KD_TP63_ERP109983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6042
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99486
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89961
Mutilating palmoplantar keratoderma with periorificial keratotic plaques	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_2798_KD_TRPS1_SRP125141	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9599
Meningeal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
lack of skin elasticity	HPO Gene-Disease Associations	1.0	null
Autosomal recessive congenital ichthyosis 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.309
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-430-ZBTB32_ZBTB32	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59462
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12157
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902531
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953761
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25735
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36157
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35327
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90719
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831813
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26183
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06098
KIAA1671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73023
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20519
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10946
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042704
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02438
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212586
congenital nonbullous ichthyosiform erythroderma	HPO Gene-Disease Associations	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11631
abnormality of the sweat gland	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5365-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28511
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3189-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Alopecia	DisGeNET Gene-Disease Associations	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291603
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.9745
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
Xylem parenchyma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12031
ITPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34052
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3685
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32886
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85734
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10282
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928008
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23729
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04181
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72214
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347778
Perturb_527_KD_RUNX3_SRP201921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56059
localization	GO Biological Process Annotations 2015	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883439
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
a549	HPA Cell Line Gene Expression Profiles	1.0	0.844586
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953761
HOXB9_02_15	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
Papillon-Lefevre disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03267
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8226
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A4S6-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8956_KO_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.443
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	1.77535
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-339-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
POLR2A	ENCODE Transcription Factor Targets	1.0	null
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18219
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28727
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15845
PMC10274772-media-2.xlsx-TFAP2A_motif_in_promoters-TFAP2A_target_genes_with_TFAP2A_motif_in_their_promoter_region_n_64_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sepsis	HPO Gene-Disease Associations	1.0	null
hsa-miR-335	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
abnormal renal physiology	HPO Gene-Disease Associations	1.0	null
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886258
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11717
Perturb_13052_KO_Il17a_SRP268747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.7839
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6108
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.403
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222417
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50055
hsa-miR-4769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Sparse Hair	DisGeNET Gene-Phenotype Associations	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49794
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9144_KD_METTL3_SRP280216	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8127-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886258
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WM983B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77419
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.904
FKBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08249
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98945
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3665	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
NOZ	DepMap CRISPR Gene Dependency	1.0	6.24118
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
Keratosis pilaris atrophicans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40822
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46582
SKMG1	DepMap CRISPR Gene Dependency	1.0	2.94147
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71648
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.9649
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5852
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63962
metal ion transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
Perturb_8659_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9199
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
abnormality of body height	HPO Gene-Disease Associations	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05173
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8002
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
Combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
Photosensitive trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03634
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41964
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906902
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intestinal hypomagnesemia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
JMJD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43338
essential	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF366	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58351
GSE144346_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42145
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
GSE158438_4_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4458	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840649
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
ichthyin	GeneRIF Biological Term Annotations	1.0	null
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8350598-NIHMS1728503-supplement-Table_S3.xlsx-Upregulated_by_SMAD4-Gene_Symbol_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Perturb_6036_KD_MBD3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.33271
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0623
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-33a	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11729
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22658
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59753
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5049
PMC10425715-Supplementary_material-Suppl.2-s2.docx-104-NEUROG3_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01782
ichthyosis vulgaris	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09125
PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06868
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80395
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88865
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02385
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104916
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32741
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-345-NHLH2_NHLH2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273696
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040338
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
lung disease	GWASdb SNP-Disease Associations	1.0	0.35374
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78685
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11252
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217511
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06672
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848696
hsa-let-7a	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68804
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907386
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.844141
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847337
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19313
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25366
recessive	GeneRIF Biological Term Annotations	1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93741
Abnormality Of The Helix	DisGeNET Gene-Phenotype Associations	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
Cicatricial lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03825
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE166004_5_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LIFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15994
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18918
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49366
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
hsa-miR-563	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC4050357-mmc2.pdf-10-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.48938
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-IRF8_mod_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20972
showed	GeneRIF Biological Term Annotations	1.0	null
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08291
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951299
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849315
colocalization	GeneRIF Biological Term Annotations	1.0	null
Perturb_15690_KO_Rela/Rel_SRP075924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.3098
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60386
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.749
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95572
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40825
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58425
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17689
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3146
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2347	CCLE Cell Line Gene CNV Profiles	1.0	1.37572
RUNX1	ChEA Transcription Factor Targets	1.0	null
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85649
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50122
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93004
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41475
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16411
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02925
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78922
hsa-miR-204	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
TP53	ChEA Transcription Factor Targets	1.0	null
TBRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5025
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
RT4	CCLE Cell Line Gene Expression Profiles	1.0	3.03059
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.45698
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9768
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2715
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1087
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29297
Photosensitive trichothiodystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73208
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
USP34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90361
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45937
six	GeneRIF Biological Term Annotations	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-2.44468
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65852
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BTF3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20399
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-IRF8_mod_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193993_5_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80399
BL70	DepMap CRISPR Gene Dependency	1.0	4.32223
hsa-miR-4301	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26374
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08156
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96565
Hypohidrosis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_15691_KO_p66/cRel_SRP075924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.0171
Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKLMS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58455
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30117
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BFTC905	CCLE Cell Line Gene Expression Profiles	1.0	1.40694
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87669
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0164
ELAVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97737
hsa-miR-27a	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17532
effect	GeneRIF Biological Term Annotations	1.0	null
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12967
nipal4	GeneRIF Biological Term Annotations	1.0	null
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43601
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17162
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907534
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22473
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypohidrosis	HPO Gene-Disease Associations	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.936
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.043
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.120545
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.217
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890257
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17532
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935134
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72455
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02141
Epidermolysis bullosa simplex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58828
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.86772
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29357
SEC23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846867
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-4778-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BFTC909	DepMap CRISPR Gene Dependency	1.0	5.7163
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70781
Leukocyte adhesion deficiency 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5379
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7801
SELENOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80613
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44711
thick epidermis stratum spinosum	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.040995
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33965
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09584
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BU-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03538
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5791
GSE193249_0_v_1_gpx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9696
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6624
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	2.25387
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42485
growth abnormality	HPO Gene-Disease Associations	1.0	null
Chronic Otitis Media	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-3187-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93453
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
autosomal	GeneRIF Biological Term Annotations	1.0	null
Magnesium transporter NIPA	InterPro Predicted Protein Domain Annotations	1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5899
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
therapeutic	GeneRIF Biological Term Annotations	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	6.30355
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310732
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.904
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05843
increased keratohyalin granule number	MGI Mouse Phenotype Associations 2023	1.0	null
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897011
MAZ	ENCODE Transcription Factor Targets	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841788
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40371
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88402
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30599
shiny skin	MGI Mouse Phenotype Associations 2023	1.0	null
possibly	GeneRIF Biological Term Annotations	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948748
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32462
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5769
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	2.0099
reticular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74525
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
alopecia	HPO Gene-Disease Associations	1.0	null
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69685
Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7380-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12278
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46077
CDAN1_02_197	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32193
TBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97618
CRIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59414
DDX19A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81524
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963442
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Brain Lower Grade Glioma_LGG_TCGA-DB-A64U-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2697_KO_ADIPOR1_SRP089784	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.39925
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055192
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
gf95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.844141
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932738
kidney	HPA Tissue Gene Expression Profiles	-1.0	-0.96576
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.876821
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87494
GSE153189_1_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLPP_KO_GSE40207_378_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35493
hsa-miR-876-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
abnormalities	GeneRIF Biological Term Annotations	1.0	null
lung_3f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0195
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937306
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30562
ZSCAN26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11785
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	2.3387
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.338
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5443
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A51W-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908784
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hyperkeratosis	MGI Mouse Phenotype Associations 2023	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6522
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19058
DIFI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5403
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
combined	GeneRIF Biological Term Annotations	1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27551
congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.27794
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06353
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30867
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46852
congenital ichthyosiform erythroderma	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5568
hsa-miR-4319	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0512
structural	GeneRIF Biological Term Annotations	1.0	null
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99301
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58897
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.48
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905584
GSE173169,GSE173170_0_v_1_epc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45031
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
NAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76978
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Jalili syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
PMC10879698-mmc1.pdf-8-ZNF572_ZNF572	Rummagene Transcription Factor Associations 2026	1.0	null
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52854
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11508
STAT1_01_154	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6033
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
COLO668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48859
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
signal	GeneRIF Biological Term Annotations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34926
Mal de Meleda	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
HS604T	CCLE Cell Line Gene Expression Profiles	1.0	1.39255
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
weight loss	MGI Mouse Phenotype Associations 2023	1.0	null
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51192
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FI-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86463
PCDHB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50949
magnesium ion transport	GO Biological Process Annotations 2023	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23042
exerts	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04844
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15999
CBX8	ENCODE Transcription Factor Targets	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5743
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32752
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30406
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1269b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.47589
PK1	CCLE Cell Line Gene Expression Profiles	1.0	1.62878
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27143
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044003
Lung squamous cell carcinoma_LUSC_TCGA-98-A539-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Icthyosis	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61127
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05893
KNS81	DepMap CRISPR Gene Dependency	1.0	2.16038
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.81262
Trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.491279
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
HGH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46691
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8664
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10225
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8285
CTSV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35538
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39602
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01389
CLPP_KO_GSE40207_388_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885251
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31326
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.88
MOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66678
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.75265
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16002
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NB5	DepMap CRISPR Gene Dependency	1.0	2.63285
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970224
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0971
ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0346
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.52041
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14013
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85989
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53245
hsa-miR-670	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59568
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of lower lip	HPO Gene-Disease Associations	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871997
desmosomes	GeneRIF Biological Term Annotations	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
central medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19011
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121879
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3323
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32386
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02046
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	1.71958
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27693
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9681
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76253
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320951
AMO1	DepMap CRISPR Gene Dependency	1.0	7.52315
urinary bladder	HPA Tissue Gene Expression Profiles	1.0	0.880581
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56951
PMC4050357-mmc1.pdf-1-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64908
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111446
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
ZC4H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18487
Brain Lower Grade Glioma_LGG_TCGA-HW-7486-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-let-7f	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838