association	dataset	threshold value	standardized value
neuroactive ligand receptor interaction	KEGG Pathways	1.0	null
Catecholaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.378143
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24306
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M14	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42069
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.58638
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20042
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488667
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11926
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Basophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
BRD-K45028867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.062
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45007
BRD-K08715132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12864
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936568
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02218
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37368
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927436
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
hsa-miR-379	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43883
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03144
GTEX-WVLH-0226-SM-3MJG6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947007
TBXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88041
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8181
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49035
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0628
KPNYS	DepMap CRISPR Gene Dependency	1.0	4.60546
BRD-K36170758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43132
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04394
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05141
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56769
BRD-K75281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44137
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90313
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01832
piromidic acid-2996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893948
TAF7L_KO_GDS2857_556_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56053
tiaprofenic acid-4091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44212
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53066
hsa-miR-4302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL3-CLOSEST_GENE_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35503
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXII-SMR_results_of_expression_levels_of_VDR_target_genes_in_prostate_and_risk_of_prostate_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18535
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SIX-SMR_results_of_expression_levels_of_VDR_target_genes_in_sun-exposed_skin_and_risk_of_melanoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
EBC1	DepMap CRISPR Gene Dependency	1.0	4.37978
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08591
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16641
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08935
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77436
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36021
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K85697068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05679
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49098
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.689226
KMS11	DepMap CRISPR Gene Dependency	1.0	2.4223
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.44359
BLOC-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02502
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01813
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877731
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5436
regulation of lipase activity	GO Biological Process Annotations 2015	1.0	null
H3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23516
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8061
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897996
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7684
CRCGN009_HEPG2_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75963
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
doxorubicin_homo sapiens_gpl550_gds848	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06721
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84362
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45586
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90885
chr2_231554288_C_T_b38	GTEx eQTL 2025	1.0	1.29019
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01229
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.850245
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33726
hsa-miR-3664-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04685
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68062
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26763
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826083
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3286
hydrocortisone_homo sapiens_gpl201_gse21909	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0789
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.40901
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057723
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45742
d10.g4.1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
T24	BioGPS Cell Line Gene Expression Profiles	1.0	0.834164
wortmannin-2703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
blood	GTEx Tissue Gene Expression Profiles	1.0	0.912377
nafcillin-2983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Salpingitis isthmica nodosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.712
BRD-K80940089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47495
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68716
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27008
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73404
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960058
BRD-K93496326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49822
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852162
desoxycortone-6758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74689
BNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4093
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044141
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11762
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230382
CRCGN011_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10305
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19316
CRCGN015_MCF10A.TP53.M_24H:C13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02585
ZNF223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90007
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09562
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3781
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.802969
E2F6	ENCODE Transcription Factor Targets	1.0	null
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
napelline-2522	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945479
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
BUB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62777
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32875
SNU668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6055
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21955
BRD-K76672835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06074
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88613
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	3.40798
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15614
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36003
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72139
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92682
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30685
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039827
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2362
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Scolex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61374
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84957
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941819
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02924
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.361
Twitch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7708
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.7
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866111
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inositol phosphate-mediated signaling	GO Biological Process Annotations 2023	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25761
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1932
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12827
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K87080069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27311
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
icSARS CoV_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.98647
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906393
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908134
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
hsa-miR-483-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
lasalocid-3021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15822
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66716
BRD-K42964587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15805
second-messenger-mediated signaling	GO Biological Process Annotations 2015	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4417
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09796
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2725
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
BRD-K81035073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32376
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18578
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51713
BAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66013
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876706
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
BRD-K76755163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01385
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
COMPOUND 8D [PMID: 24999562]	DGIdb Drug Targets 2026	1.0	3.30825
Lung adenocarcinoma_LUAD_TCGA-55-6975-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69259
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52095
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4325	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01941
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06527
RT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12295
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68252
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.915405
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.33329
BRD-K91952416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21474
proxyphylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01519
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.762
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06653
G protein-coupled peptide receptor activity	GO Molecular Function Annotations 2025	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13909
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41366
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61209548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10805
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
Floral primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71114
bhk-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968813
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07413
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12072
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesenteric adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65392756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84466
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86233
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22184
EZH2	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H0-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.239
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
JUND	ENCODE Transcription Factor Targets	1.0	null
Superficial temporal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00467
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29674
BRD-K28017317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11974
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1026-SM-48FCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26113
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.38496
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42557
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944521
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
H3C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23482
BRD-K93613839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18402
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16515
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18472
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PROCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16111
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28511
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05964
CAS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.45202
RUNX1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87177
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43353
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.70661
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31001
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11848
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07786
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85647
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
GSE237812,GSE237813_3_v_2_hmgb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870624
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848551
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68436
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062694
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6998
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83898323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18235
CIAO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04757
acetylsalicylic acid-6164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09222
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841056
RB1_KD_GSE50532_657_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856106
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902406
RUNX-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976001
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3161
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4429
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906395
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53327
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
trimipramine-4083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60247
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977738
BRD-K30013451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09045
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.00885
NUDT17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6917
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28918
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81G-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79176
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64452
communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347511
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.51301
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MICAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76119
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.5379
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.99711
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.696581
SKMM2	DepMap CRISPR Gene Dependency	1.0	2.01874
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18178356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17918
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K58219783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22502
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975449
Lymph_Node-mature nk t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0915271
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05966
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67589
hsa-miR-412	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19652
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911192
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17093
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5566
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.074
BRD-K21363211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40824
Gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.669
PRDM14	ChEA Transcription Factor Targets	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47887272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04324
THEM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65614
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	3.16266
G protein-coupled receptor activity	GO Molecular Function Annotations 2023	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8819
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15565
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.3909
C10	DepMap CRISPR Gene Dependency	1.0	9.65791
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06436
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inferior colliculus, external nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15756
r1 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04976
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05912
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608124
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40077
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.49942
C5orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12092
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10163
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18894
Lymph_Node-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	0.237138
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29497
BRD-A96334094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18414
FAM53B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98029
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.1688
Biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	3.0478
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.970918
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60144
BRD-K27476975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14372
ZWILCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61297
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881077
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
theophylline-2986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.19072
BRD-K52152765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32452
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
smooth muscle contraction	GO Biological Process Annotations 2023	1.0	null
BICR31	CCLE Cell Line Gene Expression Profiles	1.0	1.41343
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06098
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429465
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94852
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06197
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30051
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06755
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48509
zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02907
Inflorescence primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.323
hsa-miR-4758-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPC-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	3.79044
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
adrenal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.780232
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14774
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59556
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75573
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71505
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58129
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCGF2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0215
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26275
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949308
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.720345
BRD-K57734337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86013
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.744
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85788
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25117
KU-19-19	GDSC Cell Line Gene Expression Profiles	-1.0	-1.70275
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26234
Perturb_3384_KO_Hobit_SRP060705	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.24987
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17767
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34501
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856915
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
hsa-miR-4789-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.10923
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.3224
BRD-K55795421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03952
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11421
arcaine-3010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834102
indoprofen-3007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K37203382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06471
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46276
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02551
EPHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40773
Extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
neuropeptide signaling pathway	GO Biological Process Annotations 2015	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91606
PPARalpha_OE_GDS2289_244_mouse_Skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10423475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35322
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
GSE215086_8_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K06399794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10258
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.46442
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92694
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC27A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77792
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21937603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36932
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15328
positive regulation of phospholipase activity	GO Biological Process Annotations 2015	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.691069
JL1	CCLE Cell Line Gene CNV Profiles	1.0	1.56981
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.08844
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
procyclidine-2991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02982
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27401
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64317
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04112
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11345
SNU61	DepMap CRISPR Gene Dependency	1.0	2.09966
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fibrillar collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.103377
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01813
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53048
chloride transport	GO Biological Process Annotations 2023	1.0	null
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11264
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95457
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80211
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
T2-low asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.68
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08683
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40982
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11494
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975083
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.949
BRD-K99691991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50069
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76221
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34041
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14076
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.629
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844698
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262645
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05355
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
G alpha (q) signalling events	Reactome Pathways 2024	1.0	null
METTL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84721
USF1	ENCODE Transcription Factor Targets	1.0	null
Flight muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17312
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3447
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.551
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00846
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09960817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42163
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.2043
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
BRD-K66253082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48347
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corpus allatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89612
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88783
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0548
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	Reactome Pathways 2014	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4799
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GPCR ligand binding	Reactome Pathways 2024	1.0	null
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0142
trimipramine-3004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K75745696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78098
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13182
PMC4303254__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7841-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62226454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37838
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuropeptide receptor activity	GO Molecular Function Annotations 2023	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00468
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF598	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40169
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.05136
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.950817
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05608
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39933
Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7264
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33246
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7307
BRD-K20039572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09536
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.592
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73603
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17853
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.548517
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NANOG	ChEA Transcription Factor Targets	1.0	null
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26646
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02115
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921318
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58794
diloxanide-3062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17931
MITF_01_25	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59317
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.078
[125I]NEUROMEDIN U-25 (HUMAN)	DGIdb Drug Targets 2026	1.0	1.65412
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07435
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22809
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3321
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69777
POLR2A	ENCODE Transcription Factor Targets	1.0	null
BRD-K85271599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32079
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27069
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01685
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35128023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06161
Brain Lower Grade Glioma_LGG_TCGA-FG-7634-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30688
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48751
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88869
Field CA1, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01038
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
NPEPPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
BRD-K75177817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16357
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855009
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.69367
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93293
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03261
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15614
HSFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88967
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00091
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6095
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.134
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CAPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05712
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34501
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type 1 diabetes mellitus_Thymic epithelial cell_GSE11	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.71201
Villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05227
mantle zone of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04887
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0609
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41815
Lung-capillary aerocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.424947
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.72687
BRD-K91467755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05888
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10183
SLC25A30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89666
chr2_231536792_T_C_b38	GTEx eQTL 2025	1.0	1.70651
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19464
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45354
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909872
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.70691
MYBL2	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-BR-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878154
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994939
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964793
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53897
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
calcium ion transport	GO Biological Process Annotations 2015	1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.85478
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
levobunolol-3015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-3133	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14278
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04578
BRD-K08703292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20605
TIA1_KO_GSE54418_266_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975609
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCA7_Knock-in_GDS3545_560_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22862
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
CAL-33	GDSC Cell Line Gene Expression Profiles	1.0	1.60675
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38607769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41613
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55534
Floral meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
regulation of calcium-mediated signaling	GO Biological Process Annotations 2025	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37915
inorganic anion transport	GO Biological Process Annotations 2015	1.0	null
BRD-K53224741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59911
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34377350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00091
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28486
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05046
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.38435
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF484	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49019
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6875
single-organism process	GO Biological Process Annotations 2015	1.0	null
GOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22911
BRD-K16933266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64991
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.77746
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Enteric nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
VCAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828804
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64265
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870686
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09322
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.96793
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23265
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917272
GTEX-X5EB-2426-SM-4E3HX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97246
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26875
Mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.541
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7548
BRD-K02420839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59821
NEUROMEDIN S-33	DGIdb Drug Targets 2026	1.0	1.65412
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19398
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.495701
SNU2535	DepMap CRISPR Gene Dependency	1.0	2.27053
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19082
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00489
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26855
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88921
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67412
biological_process	GO Biological Process Annotations 2015	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17506
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999937
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NM4-C16	DGIdb Drug Targets 2026	1.0	1.65412
DES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26508
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96229
SMC3	ENCODE Transcription Factor Targets	1.0	null
ETS2_KD_GSE62168_259_mouse_mouse trophoblast stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	1.0	1.33537
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
BRD-K93611325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07766
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53027
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
latamoxef-3028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4235
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30624
PMC11732233-mmc1.pdf-193-PLSCR1_PLSCR1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02224
positive regulation of calcium-mediated signaling	GO Biological Process Annotations 2025	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47685
HPAC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67577
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9313
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975742
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20308
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1737
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25991
PMC5220089__F4	PFOCR Pathway Figure Associations 2024	1.0	null
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
BRD-K14210122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24703
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.487
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
NEUROMEDIN U-23	DGIdb Drug Targets 2026	1.0	1.65412
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36129
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
BRD-K23793049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40104
Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42785
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12089
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37866
BRD-K18435317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39069
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.825352
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24291
adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218613
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07482
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887448
Complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
CRCGN014_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01537
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.64487
Bract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03831
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.22494
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59982
IRAK4_Deficiency_GDS2641_653_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DLX5_KO_GSE22381_5_mouse_ear (otic vesicle)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906393
BRD-K96505704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22288
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10787
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16851
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29859
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01335
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.860069
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	2.49085
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K35560933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18312
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8028
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905243
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276495
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04647
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPK-0226-SM-3MJH6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15197
sf-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.211488
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30908
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34207
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6670-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GTEX-WH7G-1026-SM-4LVML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901958
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924163
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05385
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57568
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22408
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
dimethadione-3029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13089
Parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.278
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01237
ioversol-3026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47345
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66938
Albedo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15221
DDX60L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02813
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Slime layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
BRD-K36002293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03567
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91856
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53121
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44639
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4741
COA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86185
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09478
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.67647
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877733
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65307
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36855
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K54067431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26307
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-81-CAMTA1_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30688
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57832
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71433
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.143
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46869
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73508
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78681
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90463
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45324
BRD-K63663384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04548
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950972
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9767
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37923
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91023
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24109
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30154
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K96265882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24538
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K08389897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08776
regulation of phospholipase c activity	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953018
Brain Lower Grade Glioma_LGG_TCGA-HT-A615-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
TIA1_KO_GSE54418_265_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34145
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.843335
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5043
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00593
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
MHHES1	CCLE Cell Line Gene CNV Profiles	1.0	1.34439
hsa-miR-507	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13526697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06781
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39792
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	1.0	2.74509
calcium-mediated signaling	GO Biological Process Annotations 2025	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43411
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3714	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1864
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1943
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.57004
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1026-SM-4BOPJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36743
CRCGN008_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0859
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35346
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53592
Sarcoma_SARC_TCGA-FX-A3NJ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1268
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944666
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diclofenamide-3027	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metal ion transport	GO Biological Process Annotations 2023	1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.22176
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97284
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08986
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.861967
e2f2_21245101_mmtv-myc_lof_mouse_gpl8321_gds4094	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.019021
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70237
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NG-01A-31R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate-cd8b-positive nk t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.237138
HICS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42742
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE182840,GSE182844_0_v_1_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LPS853	DepMap CRISPR Gene Dependency	1.0	2.48232
BRD-K43390655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9741
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42186
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85584
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2122
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06020071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2141
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64067
BRD-K33497830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13419
TRPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62733
CTCFL	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0895
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.70661
Lung adenocarcinoma_LUAD_TCGA-50-5936-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7176
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FE-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55921
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1712
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11958
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
[125I]NEUROMEDIN U-23 (RAT)	DGIdb Drug Targets 2026	1.0	1.65412
BRD-K96970199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32055
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.564
NYNRIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31919
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45318
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34601
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
cation transport	GO Biological Process Annotations 2015	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.706402
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
OAW28	CCLE Cell Line Gene Expression Profiles	1.0	1.66619
nadide-7227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K21789048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97805
BICR6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96178
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09208
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K87193132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26054
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01789
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23636
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4165-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.679025
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407832
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-857-3016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48722
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60409
BRD-K07688551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09371
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.609
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09449
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37466
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
SRY	ChEA Transcription Factor Targets	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05382
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97165
DCP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22866
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K88344082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.017
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.76845
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22789
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1489
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67095
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921682
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.250977
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861477
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TT1TKB	DepMap CRISPR Gene Dependency	1.0	2.38473
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	2.55645
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39284
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24918
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMC-11	GDSC Cell Line Gene Expression Profiles	1.0	1.74018
BRD-K65107903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2652
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29887
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01813
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79225
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.840205
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.506279
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.49443
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.397
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0947
BRD-K56408846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00292
BRD-K97595801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13975
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03549
colchicine-4614	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999937
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78112
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33457
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.597594
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pentetic acid-3049	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90523
BRD-K71625503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40854
BRD-K64717502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02432
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03517
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08396
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62344
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12292
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38034
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879644
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HS-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22847
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129719
Perturb_17305_KD_Chrm1_SRP222274	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.20671
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4598
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61421
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02031
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02716
GTEX-T6MO-1726-SM-33HB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915644
BRD-K97343426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18434
BRD-K37929710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11176
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SX-SMR_results_of_expression_levels_of_VDR_target_genes_in_non_sun-exposed_skin_and_risk_of_melanoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06962
ANPR-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49877
neostigmine bromide-6735	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
TIPRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78437
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	3.82495
Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38714
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957751
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71062
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20807411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13596
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14443
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.32136
liothyronine-2984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89885
BRD-K00804254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17521
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842496
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NH-12	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47636
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856307
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H2BK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02322
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.94323
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27651
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16854
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16537
CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86946
BRD-K50287215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32808
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NMS	Pathway Commons Protein-Protein Interactions	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfafurazole-4661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853355
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09163
G alpha (q) signalling events	Reactome Pathways 2014	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16852
GSE215086_3_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96389533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14899
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-TBX21_mod_TBX21	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.962
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868702
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17575
PMC6059757__F15	PFOCR Pathway Figure Associations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72222
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28369
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3101
BRD-K11873306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44003
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14121002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09106
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.99163
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928808
lung	HPA Tissue Gene Expression Profiles	1.0	0.973887
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908924
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KDM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10054
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17465
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11867
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00667
LRRC75B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46845
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66681
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
BRD-K19103580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57955
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15871
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48373
WM-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.931796
g-protein coupled peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
BRD-K94506829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10625
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0093
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44807762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67079
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.86336
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49537
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934633
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09999
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12607
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
collagen type i trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183328
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91423
BRD-K94090114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33624
Allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22196
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37785
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951318
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59561
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60404
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2024	1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34683
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26374
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040273
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26818
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04077
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039727
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12345
MRE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95178
Gastrin-CREB signalling pathway via PKC and MAPK	Reactome Pathways 2014	1.0	null
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26623
EP300	ENCODE Transcription Factor Targets	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Signal Transduction	Reactome Pathways 2024	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MONOMAC6	CCLE Cell Line Gene Expression Profiles	1.0	1.87984
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81196
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25117
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13986
CTCF_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr2_231541144_G_C_b38	GTEx eQTL 2025	1.0	1.79321
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26137
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05933
Labial palp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75291
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
Prestwick-864-2994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59492
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37748
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66584
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.317
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.849764
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13443
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937993
STAT5A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01597
muscle contraction	GO Biological Process Annotations 2023	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954213
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852222
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
monensin-2580	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63158
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67319
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898175
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75163
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVSAT	DepMap CRISPR Gene Dependency	1.0	3.00465
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15032
BRD-K43611837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16151
BRD-K61807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31
TBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34325
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86008
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81596
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6159
BRD-K25954314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9264
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06775
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
HTK	CCLE Cell Line Gene CNV Profiles	1.0	1.81309
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00255
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70432
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.88985
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824203
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10051
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22784
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239007
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868827
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
CHP212	DepMap CRISPR Gene Dependency	1.0	5.13445
BRD-K80575072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12585
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0126
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59975583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0264
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041462
erythroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22246
sf-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.567227
BRD-K41876347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24654
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SZRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87366
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17954
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
hsa-miR-3529	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
fh94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66486
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06321
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096632
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12967
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.830831
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.28951
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Soleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
felbinac-4639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40894
BRD-K71585907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37083
membrane	GO Cellular Component Annotations 2015	1.0	null
TC2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K11442063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79393
RBM34_02_141	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.71621
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12739
BRD-K96280720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0568
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32964
Sarcoma_SARC_TCGA-MB-A5YA-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835858
BRD-K06087483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42445
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19081
Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.89761
HSFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1767
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93919
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7035
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A48U-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02521
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC45A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89689
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Sarcoma_SARC_TCGA-DX-A48P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78888
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52033
SK-BR-3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66345
NFE2L2_KO_GDS514_699_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormal metabolism	MPO Gene-Phenotype Associations	1.0	null
BRD-K87180723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64339
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36023
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28026
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96918
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50585
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45097
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28463
GATA1	ChEA Transcription Factor Targets	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75298
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Molluscan catch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
UBTF	ENCODE Transcription Factor Targets	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.761
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843642
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-A00776891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61165
IGSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42617
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
OCIAML3	DepMap CRISPR Gene Dependency	1.0	2.16694
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38778
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896712
second-messenger-mediated signaling	GO Biological Process Annotations 2023	1.0	null
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92791036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19333
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55992
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51879
BRD-K90094729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4633
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5739
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87004
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14268
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL3-OVERLAP_GENES_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88456
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3464
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06704
PHF8	ENCODE Transcription Factor Targets	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MM383	DepMap CRISPR Gene Dependency	1.0	4.4514
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23171
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43409
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00027
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29835
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35143
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940595
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63420290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76618
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45192
MCC142	DepMap CRISPR Gene Dependency	1.0	2.52053
BRD-K55766625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1246
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48669
G402	DepMap CRISPR Gene Dependency	1.0	4.98129
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906145
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74003
KYM1	CCLE Cell Line Gene Expression Profiles	1.0	2.17977
CAL120	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93676
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.03009
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28019
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14499
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.632
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.2513
meclozine-4646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95767
ioversol-6726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12152
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37958
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970817
Bone_Marrow-cd8-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.518852
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01158
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
T2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56853
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219928
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0233
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A814-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9655
GPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47033
Chronic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.756
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41537
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01493
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
LN340	CCLE Cell Line Gene CNV Profiles	1.0	1.7159
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47384
SNU626	CCLE Cell Line Gene Expression Profiles	1.0	1.83354
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20178
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PINX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30723
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15689
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12609
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.877142
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53072
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9855
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
BRD-K78847404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19403
Intestinal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2877
Perturb_15966_KO_Tbet_SRP063567	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.3073
Zona glomerulosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
ACSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5794
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.427254
Human - Tonsil - L2 - ILC1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07238
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65833
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44694
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0614
BRD-K49681465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27714
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06683
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
PMC8611677__F5	PFOCR Pathway Figure Associations 2024	1.0	null
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44528
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64556
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09945
Caki-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
GNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21415
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847823
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78656
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4209
smooth muscle contraction	GO Biological Process Annotations 2025	1.0	null
ABCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39236
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.569
Gelu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
CORL47	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43852
hsa-miR-557	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K65494150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15774
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00737
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
LPIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49587
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49292
GTEX-QLQW-0626-SM-447A6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37777
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69792
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuropeptide receptor activity	GO Molecular Function Annotations 2025	1.0	null
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09483
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40576
GATA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
KASUMI1	CCLE Cell Line Gene Expression Profiles	1.0	1.75952
hsa-miR-1225-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K33350866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62212
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12543
42MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06829
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0056
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34501
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25298
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30528
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01359
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31393518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08303
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.981
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16408
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93901
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46057
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
procainamide-4602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09738
HLF	DepMap CRISPR Gene Dependency	1.0	2.97991
CRCGN009_HEPG2_24H:K19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05463
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057059
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
BRD-K18031793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21807
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02971
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70422
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31121
7-aminocephalosporanic acid-4826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32095
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01229
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75645
EYA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79468
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00315
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30312
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
CEBPB-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827409
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.527
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3464266__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
Mandibular incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41535
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of phospholipase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996865
G alpha (i) signalling events	Reactome Pathways 2024	1.0	null
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47476
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04687
BRD-K73834056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14351
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01169
SHP77	DepMap CRISPR Gene Dependency	1.0	3.06736
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880543
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83966071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09407
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
Cardiomyopathy_Myocardial tissue_GSE5406	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.54523
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41321
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833559
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09038
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	1.4349
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86243
anion transport	GO Biological Process Annotations 2015	1.0	null
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36171
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10303
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892924
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72303
CTCF_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9356
tolnaftate-4221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86549
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
kidney cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
Invertebrate mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00916
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937393
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42862
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7608
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance transport	GO Biological Process Annotations 2023	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63789
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926503
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98995
H3K27me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Peptide ligand-binding receptors	Reactome Pathways 2014	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276145
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946363
abnormal response/metabolism to endogenous compounds	MPO Gene-Phenotype Associations	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992327
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48386
FLI1	ChEA Transcription Factor Targets	1.0	null
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01919
H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77738
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07108
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07546
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862412
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.068
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55004
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4782
Perturb_15967_KO_Tbet_SRP063567	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.23981
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83108
fh31	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.886
BRD-K92444813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45138
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40708
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83635
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11101
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952712
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Salivary_Gland-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	0.143234
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28026
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01194
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27007
positive regulation of lipase activity	GO Biological Process Annotations 2015	1.0	null
HAS-NMU	DGIdb Drug Targets 2026	1.0	1.65412
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905284
BRD-K30548577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0251
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75162
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K41009039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23116
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03287
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
BRD-K37516186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14202
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
chloride transport	GO Biological Process Annotations 2025	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
CRCGN010_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53778
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975497
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27171
BRD-K12613826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41463
Orr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833789
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24793
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81614
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60299
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RTLS-1226-SM-46MUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921456
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78962
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896826
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948303
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
hsa-miR-331-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4551
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K00243272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74871
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11867
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.12053
BRD-K45044525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20703
Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4283	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05014
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24792
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36846
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POU5F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28676
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50898
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40613
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87669982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26896
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02785
PAPOLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07098
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20856
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31585
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	2.02215
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.76027
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29076
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62963
BRD-K93357133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1047
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31152
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88815
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3786
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMSU	DepMap CRISPR Gene Dependency	1.0	2.23872
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A82976259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36542
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
2-aminobenzenesulfonamide-3063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
[<sup>125</sup>I]neuromedin U-25 (human)	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7162
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06173
BRD-K92794990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02763
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78005
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255567
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.85146
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0635
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64273
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54931539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36919
BRD-K73531877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30496
CTCF_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
simvastatin-3002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76655
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56142
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06007
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20178
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.3915
ZR-75-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976215
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09165
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
Gastrointestinal allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80405
Perturb_8944_KO_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.5235
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39672303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29153
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49443464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5904
BRD-K77177732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22388
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.855593
Inflorescence apex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53457
HGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71978
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01998
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935256
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03425
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27275
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8616957-41467_2021_27270_MOESM4_ESM.xlsx-Sheet1-Supplementary_Data_1_Differentially_expressed_genes_FDR_0_05_edgeR_exact_test_in_MLL-AF4_infant-ALL_vs_MLL-AF4_childhood-ALL_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.48568
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1188
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0726-SM-3NM9S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892228
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75212
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825188
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50899
BRD-K19817946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42968
BASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21712
Signaling by GPCR	Reactome Pathways 2014	1.0	null
hsa-miR-4751	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06438
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94476572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25956
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71337
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9918
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841
C14orf28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37053
PEO4	DepMap CRISPR Gene Dependency	1.0	2.5227
kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166768
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992263
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34068
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13994
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36879
inorganic anion transport	GO Biological Process Annotations 2023	1.0	null
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6374
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4811
BRD-K63813316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04225
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Common cold	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
Prostate adenocarcinoma_PRAD_TCGA-G9-6353-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPN-223	DGIdb Drug Targets 2026	1.0	3.30825
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04352
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.98902
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33965
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
BRD-K46121327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18053
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
smooth muscle contraction	GO Biological Process Annotations 2015	1.0	null
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24195
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11501
furazolidone-4098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-767-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
BRD-K66659401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09468
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.49801
G protein-coupled peptide receptor activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898602
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47064
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09184
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981121
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919299
SNU1066	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81505
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1193
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34479
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44504
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82069
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13501_KD_WDR5_SRP261594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.3802
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18655
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07842
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.82061
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.89161
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GPCRs, Class A Rhodopsin-like(Mus musculus)	WikiPathways Pathways 2014	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59387
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063624
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77437
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5019
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91268
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64839
raloxifene-2738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00296
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71812
chr2_231522987_G_A_b38	GTEx eQTL 2025	1.0	2.38651
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67245
ParietalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.14504
BRD-K16885048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72944
icSARA deltaORF6_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.16569
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79155
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
zona glomerulosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.872749
hsa-miR-4292	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Leaf bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8423
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52459
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Helminthiasis	DisGeNET Gene-Disease Associations	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9312
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01023
RARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88083
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38721
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39745
H3K36me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.34648
icSARS CoV_36Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.09396
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11761
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5807
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chlortalidone-3198	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4760-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_17290_OE_lncRNA5251_SRP239063	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.05978
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24953
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47801
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.434196
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45398957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21521
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7983
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.06017
KOPN8	CCLE Cell Line Gene Expression Profiles	1.0	1.46818
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49893
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03615
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95547
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-466	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K21467089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63732
ZNF501	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56112
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77796
GOLGA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27963
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76784
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23053
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K27221973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22456
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11148
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01453
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75363
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915708
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
calcium ion transport	GO Biological Process Annotations 2023	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.24945
hsa-miR-3194-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
GSE154464_0_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.50807
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.27945
OPTN_KD_GDS2892_268_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00749
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85655
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4975
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948871
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99131664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20262
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13755
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05015
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842155
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66283
HT-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4761
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Subiculum, dorsal part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0756
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997581
BRD-K69493165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98217
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.56854
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.198
hsa-miR-4803	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87015
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
PMC4303254__F3	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81417
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74841
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14985
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11867
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	2.3044
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39221
neuromedin U receptor activity	GO Molecular Function Annotations 2025	1.0	null
SW626	DepMap CRISPR Gene Dependency	1.0	2.00539
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56979
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32974773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66263
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
interleukin-4 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.4076
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01074
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66056
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05058
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle contraction	GO Biological Process Annotations 2025	1.0	null
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
chr2_231518438_T_C_b38	GTEx eQTL 2025	1.0	1.14316
PMC9724253-12920_2022_1407_MOESM1_ESM.pdf-8-PBX4_PBX4	Rummagene Transcription Factor Associations 2026	1.0	null
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02714
BRD-K94766933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09029
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898466
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0142
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30301
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63673
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15996
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
BRD-K06058625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01758
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5103
Trachea-cd8-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	2.86646
BRD-K41707029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18677
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A01717918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35845
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56273
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055302
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5478
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82788
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39079
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.950886
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2188
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.909925
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40562
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01363
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7002
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5974
BRD-K03221986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88245
BRD-K44236678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37958
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
FM3A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
NDUFA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18122
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HS870T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5131
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983267
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10411
e2f1_21245101_mmtv-myc_lof_mouse_gpl8321_gds4094	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.44385
BL-41 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63885
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963605
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885929
BRD-K61053165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32575
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264696
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0678
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888084
Prostate adenocarcinoma_PRAD_TCGA-EJ-7793-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A85231803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2403
Cervical canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47866
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76804
BRD-K84391462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07859
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CADM1_Deficiency_GDS2027_722_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48926
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45071
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861742
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90211
Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58548
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961037
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20131
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900978
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
Th2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.56
reserpine-3003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83553001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14454
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7307
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73525
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53425
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	3.12028
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917316
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14785
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48474
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6635
BRD-K14970242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04916
Extrinsic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0526-SM-4BRWD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956242
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.689634
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38214
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06738
CHD2	ENCODE Transcription Factor Targets	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
PU-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46812
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39655
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
monoatomic anion transport	GO Biological Process Annotations 2023	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0508
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255234
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34689
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.051564
BRD-K04877855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11947
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00677
hsa-miR-4691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22236
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
tinidazole-4548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.213621
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0526-SM-32PM7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89656
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71953
inorganic anion transport	GO Biological Process Annotations 2025	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.855593
Prostate-nkt cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0962818
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90967
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
BRD-K77024507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19334
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05549
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33087
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22966
Kidney-cd8-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.00237733
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04577
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K08427390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10829
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52911
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62197
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46595
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17435
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00691
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08215
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840481
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
BRD-K46126513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46217
BRD-K37765157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.001
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33762
MZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83867
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.3582
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10968
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46357
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuromedin U receptor activity	GO Molecular Function Annotations 2023	1.0	null
phospholipase c-activating g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.9883
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868527
Mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.684
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890798
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847002
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23048
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EI-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pollen allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NMS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3812
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
BRD-K44328896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45701
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958249
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-668	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
NMU	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39029
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-TBX21_mod_TBX21	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Lung adenocarcinoma_LUAD_TCGA-44-6777-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22096
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28579
BRD-K58044926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02748
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cho cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143827
fh60	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
RD	CCLE Cell Line Gene CNV Profiles	1.0	2.23585
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03097
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75002
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69237
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99085
LXF289	DepMap CRISPR Gene Dependency	1.0	2.09303
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
Ventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MERO41	DepMap CRISPR Gene Dependency	1.0	4.26733
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00718
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11094
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879143
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46451
UQCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67624
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20812
PEG40-NMU	DGIdb Drug Targets 2026	1.0	1.65412
chloropyramine-3011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63743
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39214
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
CHK2_KD_GSE54268_668_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RWSA-1326-SM-47JX9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907473
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31577
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72524
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986339
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19605
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.30364
hsa-miR-4441	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
neurotransmitter receptor activity	GO Molecular Function Annotations 2015	1.0	null
TP53INP2_KO_GSE54917_384_mouse_Quadriceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
CRCGN008_HEPG2_24H:I21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02575
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13989
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4101-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303559
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03656
OCIAML3	CCLE Cell Line Gene Expression Profiles	1.0	2.3342
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71571
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44898
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79533
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.44281
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24978
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPCR ligand binding	Reactome Pathways 2014	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99021
MOLT16	CCLE Cell Line Gene Expression Profiles	-1.0	-3.22316
BRD-K43341819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04912
ZNF143	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9842
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11909
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3115	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12624
TRIP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19129
BRD-K51511759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54487
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
SLC38A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3514
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
BRD-K25638876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1807
KMBC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67339
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44547
mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55408
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10268
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86549
VMRC-RCZ	GDSC Cell Line Gene Expression Profiles	1.0	1.5976
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39583
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
eosinophilia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.374438
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938052
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07433
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23636
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-X638-0226-SM-47JZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13716
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04975
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.149
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00719
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953744
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73155
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17276
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00961
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999937
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.639214
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55171
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A16760970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0541
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87384
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53764
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01572
hsa-miR-4667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73681
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057835
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76122
EVSA-T	GDSC Cell Line Gene Expression Profiles	1.0	1.6237
H3255	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80528
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65882
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0682
SLC22A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99357
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71548
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11292
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.709666
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23205
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98919
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.811183
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98375
propantheline bromide-3013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6082
NMS	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12653
Mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0611
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964358
Pars tuberalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79212
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944309
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV434	CCLE Cell Line Gene Expression Profiles	1.0	1.56196
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.6218
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999937
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01726
BRD-K22670776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44846
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196117_6_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35335
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05591
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12742
Adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3541
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4482
G alpha (i) signalling events	Reactome Pathways 2014	1.0	null
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04496
Leiomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59436
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06454
BRD-K32251128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8965
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10393
OCUM1	DepMap CRISPR Gene Dependency	1.0	2.35269
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941586
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831494
Food allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20712
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18125
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
PMC10223558__F5	PFOCR Pathway Figure Associations 2024	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85908443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42178
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892201
UACC62	DepMap CRISPR Gene Dependency	1.0	2.22245
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30248
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070753
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82309
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10085
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Non-odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.23539
PTK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95954
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10317
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7118
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04647
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tetroquinone-2999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-449a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
RBM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09058
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35431
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00341
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcium-mediated signaling	GO Biological Process Annotations 2015	1.0	null
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01379
BRD-K75869048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32153
BRD-K54660148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19488
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847397
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
hsa-miR-3689e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXIII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_breast_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94967
hsa-miR-1205	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lorglumide-4658	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13545
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2639
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	2.1018
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0226-SM-4AT4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866279
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K04614055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2546
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12441
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835239
Disease	Reactome Pathways 2014	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976001
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00496
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939784
HS706T	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1002
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37854
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67141
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0114
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98375
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99758
neuropeptide signaling pathway	GO Biological Process Annotations 2025	1.0	null
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.79546
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
Eye-eye photoreceptor cell	Tabula Sapiens Gene-Cell Associations	1.0	6.24702
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37866
Mesenteric lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.258
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	1.50081
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4703-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.52288
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NL-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU410	DepMap CRISPR Gene Dependency	1.0	2.00775
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
S-layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24387453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19837
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
BRD-K87654551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16852
BRD-K92524823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14275
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5880-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061591
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43997
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.933169
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34024
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94587
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	5.18012
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90626
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2014	1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5375
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3UE-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51569
abnormal response/metabolism to endogenous compounds	MGI Mouse Phenotype Associations 2023	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.261
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65261
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54683
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95211
BRD-K05841284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73172
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45846
positive regulation of phospholipase C activity	GO Biological Process Annotations 2023	1.0	null
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23928
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCC-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
chr2_231529808_A_G_b38	GTEx eQTL 2025	1.0	3.72153
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999422
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K83820627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75132
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26199
BRD-K66912462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76675
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864106
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53216
PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-116-ESX1_ESX1	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08422
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61215
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04647
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84846
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
OCIAML2	CCLE Cell Line Gene Expression Profiles	1.0	1.67106
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65949
SNU1079	DepMap CRISPR Gene Dependency	1.0	2.71342
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06813
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
hsa-miR-4270	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18581
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26814
KRAS.AMP.LUNG_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_02_198	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62803
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87836
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48346
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70273
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01057
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25713
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71264
positive regulation of phospholipase c activity	GO Biological Process Annotations 2015	1.0	null
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68257
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89494
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Neuromedin U receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.08005
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24605
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6552
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882276
NUDT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58209
GSE131673_0_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
activation of phospholipase c activity	GO Biological Process Annotations 2015	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24889
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	1.17017
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36496
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31953
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87474
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87878
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spleen-type i nk t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.69266
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966079
zuclopenthixol-4261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22422
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BRD-K84062787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10537
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987525
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52274
CRCGN016_MCF10A.WT.HP_24H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2704
LC1SQSF	CCLE Cell Line Gene Expression Profiles	1.0	1.5174
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64296
Prestwick-682-6638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.99683
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
C1QTNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06698
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33431
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14913
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-361 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885645
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09566
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.083186
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.158
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
hsa-miR-671-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
neuromedin U binding	GO Molecular Function Annotations 2025	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17739
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85922
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50565
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02752
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50396
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K85532500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66709
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61613
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25502
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050998
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3445_OE_Sca17_SRP248035	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.91266
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pasteurellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
interleukin-28 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
RBP2_deficiency_GDS2731_62_mouse_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3689f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
Kidney-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	0.941422
A375SKINCJ2	DepMap CRISPR Gene Dependency	1.0	2.76556
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.864209
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.40589
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen	HPA Tissue Gene Expression Profiles	1.0	0.895997
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01759
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67047
BRD-K05090634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63085
BRD-K50718861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83801
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4067
MBD3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65319
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68069
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23814
superior parietal lobule, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904463
HCC95	CCLE Cell Line Gene Expression Profiles	1.0	1.52389
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14995
BRD-K38984040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01191
BRD-K09261031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30855
NCIH647	DepMap CRISPR Gene Dependency	1.0	6.21263
NEUROMEDIN U-25	DGIdb Drug Targets 2026	1.0	1.65412
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916721
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00434
Lung-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.17618
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28999
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9768
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10994
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
93T449	DepMap CRISPR Gene Dependency	1.0	3.88118
BRD-K15639930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0294
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07104
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.887715
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898112
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2619
BRD-K82785545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06206
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.46253
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02189
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16315
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10576
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05023
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74936
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1819
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23172
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77759
OVMIU	DepMap CRISPR Gene Dependency	1.0	4.84739
[125I]NEUROMEDIN U-8 (PIG)	DGIdb Drug Targets 2026	1.0	1.65412
LEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60427
BRD-K84517695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64787
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45258
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Spot adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22846
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
BRD-K01278504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00983
BRD-K11577431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30984
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31961
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.889893
hsa-miR-4786-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2645
SSBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99245
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21612
BRD-A68842442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0717
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59339
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20431
neuropeptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K57274378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11825
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65059
HMGN3	ENCODE Transcription Factor Targets	1.0	null
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.524377
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40677
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gk1.5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44615
MEL-JUSO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	0.896952
MDA-MB-435S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921142
BRD-A98203122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16676
BRD-K01225799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1067
Recycling endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
BRD-K86721033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35922
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2367
FBXO38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13115
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15133
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38864
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06906
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64743
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27055
GTEX-RTLS-0726-SM-46MV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22894
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24047
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.89166
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20979
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227707
hsa-miR-4663	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CAPN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16955
VDR-24763502-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11373
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915068
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998436
NMU	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CRCGN009_HEPG2_24H:E05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01513
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65209
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-876-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K14925361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09681
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20282
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.5864
myc_17159920_cancer_cell_lines_lof_human_gpl570_gds2526	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.733034
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.27249
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68926
CCT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91454
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00901
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.80942
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15669
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
IgE immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.596
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00015
BRD-K18345986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15521
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123887,GSE123888_2_v_1_hpgd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17526
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45229
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08949
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52962
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14438
RXRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59128
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06333
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03849
DERL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79353
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43793
HLC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92643
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02406
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61651560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06273
NCIH358	DepMap CRISPR Gene Dependency	1.0	2.77616
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73601
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33457
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51647
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.983
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5078
ANTKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47012
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33606963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29487
H3K36me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	1.0	1.41059
Perturb_16523_KO_Ahr_SRP318414	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.0132
Fat-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	1.64571
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72127
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.49889
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04449
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95245
Rectum adenocarcinoma_READ_TCGA-F5-6864-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900603
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.42257
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3691
HS729	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49613
BRD-K09900382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44405
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7872
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1175
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9766
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59471
BRD-K50815029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18895
BRD-A06158172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28869
BRD-K51270604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10481
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.4212
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09251
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78625
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
hsa-miR-637	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Type II polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75271
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.925479
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DJ-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37923
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97133
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081656
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
calcium-mediated signaling	GO Biological Process Annotations 2023	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7136
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872592
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48032
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0244
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852308
neuromedin u receptor activity	GO Molecular Function Annotations 2015	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898326
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11867
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91215
Lung adenocarcinoma_LUAD_TCGA-49-6744-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73998
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68161
Blood-type i nk t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0915271
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0266
paromomycin-3017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22124
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
hsa-miR-370	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.431077
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3202
NCI H226	BioGPS Cell Line Gene Expression Profiles	1.0	1.32863
IST-SL1	GDSC Cell Line Gene Expression Profiles	1.0	1.75555
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38514
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65078
WAOSEL	DepMap CRISPR Gene Dependency	1.0	10.6937
CREB1	ENCODE Transcription Factor Targets	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976215
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47005
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.341272
Sarcoma_SARC_TCGA-DX-A48O-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92334
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34241
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76806
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76461
Male cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902558
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04292
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648532
CPEB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32933
PMC3464266__F3	PFOCR Pathway Figure Associations 2023	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.70661
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DUSP26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56904
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.729385
Lamina propria	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
BRD-K75148160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24034
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59989
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.35079
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.00485
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882276
GTEX-R55G-2426-SM-2TC5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930577
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89489
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039537
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0552
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9046
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42044
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.694946
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14785
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2554
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92685
GMCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81351
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Respiratory allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.817
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16560691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80749
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9442
anterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1783
agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.373698
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.66499
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49533
Signaling by GPCR	Reactome Pathways 2024	1.0	null
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF331	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86301
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877812
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03165
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85127
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11715
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNASE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47218
DMS-273	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928759
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-1126-SM-3DB7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874409
lm5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13895
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12484
peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35442
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958808
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
Allergic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
monoatomic anion transport	GO Biological Process Annotations 2025	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942228
UTP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32623
BRD-K10705624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67874
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85437
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84834
Submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
AKAP17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64976
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54527
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01404
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01377
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.80489
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33447
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52383401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.102
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999937
Liver-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	0.941422
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965036
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SVIII-SMR_results_of_expression_levels_of_VDR_target_genes_in_breast_tissue_and_risk_of_breast_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8056
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03166
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1618	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05302
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850759
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25225
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04647
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.8476
hsa-miR-449b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
mestranol-3008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K85977570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15281
RT11284	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63032
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10929
brain	HPA Tissue Gene Expression Profiles	-1.0	-0.933212
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71361
PMC5220089__F4	PFOCR Pathway Figure Associations 2023	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63943
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89653
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Polytene chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08009
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26321
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04595
TE6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54348
DTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61969
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
CRCGN008_HEPG2_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30305
transport	GO Biological Process Annotations 2015	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21357
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48478
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41254
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843706
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13886
CBX3	ENCODE Transcription Factor Targets	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27833
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	0.958178
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14116
Nerve plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468824
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99265
repaglinide-3558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9659
renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.225573
Inner mucus layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.67
hsa-miR-3689a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-XOT4-0226-SM-4B66Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42825
chr2_231527265_A_G_b38	GTEx eQTL 2025	1.0	4.06818
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	4.07723
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986862
peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.02591
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833711
BRD-K24312231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75453
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXV-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_hepatocellular_carcinoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933334
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75497233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21971
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13312
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3528
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1334
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70013
receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RI1	DepMap CRISPR Gene Dependency	1.0	2.98839
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73906
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0619
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881956
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62872
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937151
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40658
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23365
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3249
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60769
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916098
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924337
TTC442	DepMap CRISPR Gene Dependency	1.0	2.34849
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75119
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.34378
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.8993
PMC12211054-spectrum.00100-25-s0002.pdf-69-NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
Gamma delta T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT1197	CCLE Cell Line Gene Expression Profiles	1.0	1.42584
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Peripheral motor neuropathy_Sciatic Nerve_GSE1947	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.69134
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43794
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10636
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976001
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0018
BRD-K99028283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.502
fluorouracil_homo sapiens_gpl550_gds848	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K71486446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39898
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.30904
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884213
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.763226
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
ELF1	ENCODE Transcription Factor Targets	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-0.824113
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14595_KO_FOXA2_SRP161699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.78074
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49984
skin	HPA Tissue Gene Expression Profiles	-1.0	-1.00451
Thymus-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	0.424947
REH	GDSC Cell Line Gene Expression Profiles	1.0	1.55283
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918486
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77251
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81742
FBXW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65658
BRD-K62976536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80108
Colo-201 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
LN235	DepMap CRISPR Gene Dependency	1.0	2.81441
fh32	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.772
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.48866
Uterine leiomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16754
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160761
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3739
Perturb_12914_KD_FUT8_SRP342334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42941
tanespimycin-2685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.443689
BRD-K95460104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.518
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
CAL851	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50264
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44622
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19977
boldine-4004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K48145537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09758
CRCGN008_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66565
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71722
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063972
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0607
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46241
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76371
BRD-K97707303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2226
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30196
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840248
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34398
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76605
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06862
CRCGN016_MCF10A.TP53.M_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26074
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02913
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54122
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97602
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17942
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A96183603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50457
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40808
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.86192
activation of phospholipase C activity	GO Biological Process Annotations 2023	1.0	null
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
TMEM123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56253
BRD-K34624391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00547
BRD-K82145108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09955
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13311
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.38915
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3366
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37482
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03807
ZNF384	ENCODE Transcription Factor Targets	1.0	null
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64414
HOS	CCLE Cell Line Gene CNV Profiles	1.0	1.65601
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gizzard	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
SUPM2	CCLE Cell Line Gene Expression Profiles	1.0	2.00249
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7999
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4327
USP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0381
optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2559
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K91421454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59501
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
Alcoholic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mucosal mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99363
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16341
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	2.08092
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.88241
BRD-K54023716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2402
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09835
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210253
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13953
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-296-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976001
EGR1	ENCODE Transcription Factor Targets	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6523
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30067
CRCGN014_HEPG2_24H:L17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04604
ZNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99376
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89185
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.747631
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3689b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
RAB3IL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08385
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Natural killer cell_Bone marrow_Human	CellMarker Gene-Cell Type Associations	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22467
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3093
GSE193402_0_v_4_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59501
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4255
BRD-A86748098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3497
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
BRD-K92374432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47928
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84338
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.4728
THY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06086
Corneal astigmatism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
PMC6059757__F15	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.29479
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945271
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69257
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853616
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05772
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Hypereosinophilic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47195
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15237
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59556
TMEM201	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67941
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64404450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20467
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58354
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857973
YY1	ENCODE Transcription Factor Targets	1.0	null
PMC9396374-Table_4.XLSX-AR_related_genes_from_OMIM-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4810-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
GLC82	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20308
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1174
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.499
BRD-K87808996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52841
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PAX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K05501176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43843
BRD-K07959057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2456
BRD-K77603027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6913
Colo-205 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
FOXM1	ENCODE Transcription Factor Targets	1.0	null
BRD-K50884475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31935
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
Neuromedin U receptor, type 1	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K40057256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18296
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18403
collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.059405
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51951
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31524
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
Uropygial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13098
BRD-K17885598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08787
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00628
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45752
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
ASAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88722
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48935
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40406
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SLC35B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43157
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8999
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03204
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09468
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83936
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.942324
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040915
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93948
metal ion transport	GO Biological Process Annotations 2015	1.0	null
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39729
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82427
Spleen-mature nk t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.17618
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.98
chr2_231524876_CCCT_C_b38	GTEx eQTL 2025	1.0	1.32526
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44186
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXIV-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_melanoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
496100310_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.312
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51906
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00923
[<sup>125</sup>I]neuromedin U-8 (pig)	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
METTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18039
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A42433574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46307
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24553
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918076
Lung adenocarcinoma_LUAD_TCGA-44-6144-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Femoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27608
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28182
wehi164	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.875983
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12527
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86605
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14598
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
EIF4ENIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77114
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.52395
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59501
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.4243
ketorolac-5988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2412
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67881
muscle system process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85452
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15238
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89328
BRD-K71533707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10693
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971892
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K83115435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56762
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K64992851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77507
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.22699
Bone_Marrow-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	1.5518
BRD-K62841603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49296
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46034
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-UT-1B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.88586
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.21805
prochlorperazine-6664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.332294
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15166
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91699
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923737
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19471
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06889
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19889
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00163
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.51264
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976001
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
PMC11991920-41556_2025_1639_MOESM10_ESM.xlsx-DEGs_MI_at-RA_vs_MI_Ctrl_HSPCs-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59907
upper dorsal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38136
BRD-A26952628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09812
NRF1	ENCODE Transcription Factor Targets	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57437
JHH7	DepMap CRISPR Gene Dependency	1.0	2.03472
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	3.93841
BRD-K80921954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07259
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79252
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927899
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25868508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19478
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856915
cho-k1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316951
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422673
BRD-K69487032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58404
BRD-K23296676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18371
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
BRD-A08820802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38971
CAL-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01839
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853207
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998951
PML	ENCODE Transcription Factor Targets	1.0	null
BRD-K93819193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28306
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brockmann body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83076
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leiomyosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
corl23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08517
neuromedin U binding	GO Molecular Function Annotations 2023	1.0	null
Cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.172
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45569
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20228
cefsulodin-2988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K16800391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08667
Glioblastoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-4266	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52427
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13256
novobiocin-2990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.937917
Gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.513
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051216
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
BRD-K31215362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19759
LS-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
Thiazide-induced adverse metabolic effects in hypertensive patients	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.854
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7452
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56519
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80779
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84264
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8039
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04647
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30688
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.434196
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721577
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077317
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05322
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049023
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXVII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_sarcoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
COLO320	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6603
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.02742
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01755
Thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
HEY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96064
POU5F1	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01401
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845519
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38932
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06652
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7147
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61958
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50721666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41331
BRD-K86330848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00363
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57349
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061844
BRD-K58971526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40071
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72642
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5331
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TARDBP_02_129	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61667
anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215341
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81925
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09038
USF2	ENCODE Transcription Factor Targets	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976001
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26141
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97786
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435672
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876656
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66205
hsa-miR-4459	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
BRD-K47947160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16413
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.3964
Adrenomedullin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857878
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95115
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29835
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72497
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1608
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906484
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73739802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7956
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
BRD-K66733186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06302
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67974
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LB2241-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.96641
BT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7877
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19A-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4772-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46677
BRD-K38997615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98657
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
Eosinophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.869
Lung-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.138479
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.351
CRCGN016_MCF10A.TP53.M_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37231
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-RUNX3_mod_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836676
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreas-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	0.377995
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33277
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K80359388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31124
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
TOMM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82734
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31665
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045207
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24171
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38815
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.73658
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51827
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2622
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:E18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20275
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070768
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.38111
U-87-MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76767
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78938
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49713
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29663
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31454
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phospholipase C-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2856
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86471
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K29418729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08987
BRD-K98117883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70091
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03705
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30073
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
TXNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57442
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17321
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
BRD-K83562499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90348
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32386
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0707
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34971
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	2.80178
Neuroactive ligand-receptor interaction	KEGG Pathways 2026	1.0	null
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19886
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33999
Cestode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.56607
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Type 2 diabetes mellitus_Hepatic Tissue_GSE2899	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.41893
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22914
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.63035
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
neuropeptide binding	GO Molecular Function Annotations 2023	1.0	null
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56095
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03934
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31886
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1506
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36934
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29376
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18361
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
SIRT6	ENCODE Transcription Factor Targets	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20854
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93185
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62721
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873687
DESI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95306
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37152
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
hsa-miR-4499	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hsa-miR-31	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058312
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ifenprodil-5044	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06653
minoxidil-4216	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3383_KO_Blimp1/Hobit_SRP060705	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.78218
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23048
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99882
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915001
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
Spleen-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	5.63664
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4555
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86407
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11632
tolbutamide-4362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30721
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11264
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.71179
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
HAUS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30281
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92273
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02496
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle contraction	GO Biological Process Annotations 2015	1.0	null
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-2.67288
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62849
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BPHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27657
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	1.46162
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CADM1_KO_GDS2026_301_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-A71722688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01244
NEUROMEDIN U-8	DGIdb Drug Targets 2026	1.0	1.65412
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08203
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06480376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0663
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65314
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17431
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
ACC3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11733
hsa-miR-4795-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39774
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40077
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856512
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
GTEX-TKQ1-0426-SM-4DXT4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00864
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75054
BRD-K39476596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03572
Peptide ligand-binding receptors	Reactome Pathways 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
ZNF672	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20252
S117	DepMap CRISPR Gene Dependency	1.0	3.38947
CLDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50966
GTEX-XV7Q-2326-SM-4BRVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831294
Clc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3124-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3223
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
PHF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20959
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54867
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18105
BRD-K43700313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02792
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.195183
HDAC2	ENCODE Transcription Factor Targets	1.0	null
DKMG	CCLE Cell Line Gene Expression Profiles	1.0	1.35607
BRD-K83752863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07188
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872347
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95026
BRD-K59831227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51276
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040342
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27447
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.914126
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
CDYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38166
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
RXRA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908134
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K98224452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05759
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64325
cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374993
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.40008
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
frontal operculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.890755
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77732
Sarcoma_SARC_TCGA-PC-A5DL-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63779242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26152
scopolamine-4219	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20454972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80332
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.9852
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946035
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605709
BRD-K05940224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90459
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29674
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46567
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36698
Vastus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.69098
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16212
BRD-K81124412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58781
BRD-K05409106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74127
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902094
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10739
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908453
ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.24225
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64325
RFX5	ENCODE Transcription Factor Targets	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45833502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10007
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975083
8-MG-BA	GDSC Cell Line Gene Expression Profiles	1.0	2.07565
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76109
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3051
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38146
SW948	CCLE Cell Line Gene CNV Profiles	1.0	1.33153
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28716
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
Perturb_17597_KO_Il25_SRP247658	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.72593
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71253424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32598
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
BRD-K30594227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33944
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59942
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28201
GTEX-OXRK-1426-SM-3NB19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05469
BRD-A35495382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18812
Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COMPOUND 5D [PMID: 25815150]	DGIdb Drug Targets 2026	1.0	3.30825
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
hsa-miR-129-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
chloride transport	GO Biological Process Annotations 2015	1.0	null
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54638
Tenia tecta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056888
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09928
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79824
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03315
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99894
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39302
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
Plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
GATA2_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
[<sup>125</sup>I]neuromedin U-23 (rat)	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05329
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26042
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933464
BRD-K58480962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5434
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.84756
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07636
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33429
BRD-K97624648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.618
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28371
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.432
PAOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26598
CYB5D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96507
STAT3	ChEA Transcription Factor Targets	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29835
CYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.67639
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6662
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90625
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89731
chr2_231557675_A_G_b38	GTEx eQTL 2025	1.0	1.42784
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-CLOSEST_GENE_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882276
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06173
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
inositol phosphate-mediated signaling	GO Biological Process Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872047
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08622
interleukin-27 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31824
GSE215086_8_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3229
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27743
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969325
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03545
ZNF563	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82976
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23432
BRD-K50961262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39014
PI4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70991
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51636
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01301
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF776	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71584
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842285
BRD-A77328129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48716
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.45138
HTATSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08915
CHP126	CCLE Cell Line Gene CNV Profiles	1.0	1.9345
cell part	GO Cellular Component Annotations 2015	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KSR1_knockout_126_GSE28228	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.4054
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EGFL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09144
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53496
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.32943
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07802542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09908
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08986
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0678
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4504
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6B7-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01734
BRD-K15502712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92808
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
l90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66848
SLC30A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04316
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVISE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRKAG3_Mutation (R225Q)_GSE4067_390_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
STK31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2712
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.86095
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51389
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09306
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92114
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1294
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5736
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4287
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.720191
BRD-K52731958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20647
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2A	ENCODE Transcription Factor Targets	1.0	null
tolmetin-3009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
GSE165647_6_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.24577
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.45428
hsa-miR-645	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16152
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03254
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung-cd8-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.143234
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.795
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20065789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12207
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75173
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34549
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09584
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
Prostate adenocarcinoma_PRAD_TCGA-G9-6367-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922615
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular signaling cassette	GO Biological Process Annotations 2025	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98989
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GT1-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28762
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.01418
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23171
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phospholipase C-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.68602
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17789
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5236
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02536
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48446
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37309
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12159
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94728
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26475
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828492
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93614
Adrenal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38146
TCF12	ENCODE Transcription Factor Targets	1.0	null
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
BRD-K97377031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53091
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
SNU738	CCLE Cell Line Gene Expression Profiles	1.0	2.2146
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88246
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37225
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068213
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83391
BRD-K26257310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41837
BRD-K13941052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40745
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41335
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63263229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65234
theobromine-2995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77265
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.45238
GPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70503
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934473
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84107
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K37328981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40757
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.3214
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1116	DepMap CRISPR Gene Dependency	1.0	3.00995
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59117
MEF2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02632
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04647
Arcuate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67025
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47302
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09472
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28182
hsa-miR-34c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19229
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46219
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85557
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66841501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41153
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.828
C1orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69959
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65315
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0215
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07459
ANAPC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78599
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51298
BRD-K33194123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31302
hsa-miR-4253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02534
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89274
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUV39H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78883
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060903
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Nurse cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9816
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuropeptide signaling pathway	GO Biological Process Annotations 2023	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38852
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.138
MONOMAC1	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22774
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46824282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38726
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28853245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55191
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
JY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Psoas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.1326
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06864
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13823
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5014
WM983B	CCLE Cell Line Gene Expression Profiles	1.0	1.63032
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62776
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63941
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPN-267	DGIdb Drug Targets 2026	1.0	3.30825
BRD-K82637883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20449
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-34a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Alveolar lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
G402	CCLE Cell Line Gene CNV Profiles	1.0	1.55206
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fast muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.0742
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924709
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08161
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78852
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48393
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44907
bhk cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269521
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83645
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68091
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44673
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9794