association	dataset	threshold value	standardized value
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999336
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL32	Pathway Commons Protein-Protein Interactions	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890358
SRC_activemutant_51_GSE15815	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.15516
DEL	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.8452
PMC12494973-41467_2025_63880_MOESM1_ESM.pdf-168-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845405
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.834551
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
EML4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6344081-elife-40364-supp5.xlsx-PLZF_peaks_H3K27Ac_unchanged-Unnamed_10_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28888
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5459-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Leaf tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914324
POLR2I	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CM-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361574
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9653
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7799
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3092
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.36635
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927348
SF3B3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8578
JB-89-SI60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234107
EIF3H	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02261
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65006
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
SET2	DepMap CRISPR Gene Dependency	1.0	2.35711
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHOP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-6.06357
cellular process	GO Biological Process Annotations 2015	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.925831
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.980656
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41231
A-CA-04-2009(H1N1)_30Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.02488
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0481
MCF7_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127062
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECI1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11651170-pt4c00533_si_002.pdf-97-ZNF33A_ZNF33A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00389
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
EIF4H	Pathway Commons Protein-Protein Interactions	1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	1.0	3.99117
abnormal mitochondrial ATP synthesis coupled electron transport	MGI Mouse Phenotype Associations 2023	1.0	null
GPATCH4	Pathway Commons Protein-Protein Interactions	1.0	null
ZC3HAV1	Pathway Commons Protein-Protein Interactions	1.0	null
SRRT	Pathway Commons Protein-Protein Interactions	1.0	null
MCM3	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265527
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229673
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23187
NE-34-OZ69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32147
OACM5-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.17015
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0256
SARS-CoV MA15_Day7-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71626
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRC2C	Pathway Commons Protein-Protein Interactions	1.0	null
DUS3L	Pathway Commons Protein-Protein Interactions	1.0	null
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39081
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829469
NAA38	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
abnormal placenta morphology	MPO Gene-Phenotype Associations	1.0	null
H1FX	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.80019
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PBXIP1	Pathway Commons Protein-Protein Interactions	1.0	null
ECH1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
CSDE1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7302-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4994_METTL16_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.52307
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56345
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995586
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143174
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26866
LSM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4206
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84014
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.453
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944237
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SLC25A11	Pathway Commons Protein-Protein Interactions	1.0	null
LIN28A	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934747
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23529
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.880113
mitochondrial part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0459
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.28084
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS2	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal mitochondrial crista morphology	MPO Gene-Phenotype Associations	1.0	null
mRNA_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
PRPF3	Pathway Commons Protein-Protein Interactions	1.0	null
C19orf53	Pathway Commons Protein-Protein Interactions	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LSM14B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903023
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864721
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22044
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11283
ZCCHC3	Pathway Commons Protein-Protein Interactions	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.401861
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28054
mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.940689
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21141
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.147
organelle	GO Cellular Component Annotations 2015	1.0	null
HARS2	Pathway Commons Protein-Protein Interactions	1.0	null
KELLY	DepMap CRISPR Gene Dependency	1.0	2.40596
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.94966
MRPL39	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PB-09-OE00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305565
Plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.04
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.26261
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17088
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44448
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.496175
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58039
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9493
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.887603
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS21	Pathway Commons Protein-Protein Interactions	1.0	null
U2AF1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.918436
mitochondrial	GeneRIF Biological Term Annotations	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01353
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
Glycogen cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KM12	CCLE Cell Line Gene Expression Profiles	1.0	1.54594
znf263_19887448_helas3_lof_human_gpl6884_gse19146	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.502171
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.925831
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274212
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3168
SNU719_STOMACH	CCLE Cell Line Proteomics	1.0	8.08313
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
glycerol-3-phosphate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.819
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975389
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0709
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
9587_UMPS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.52304
RTCB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE207787_3_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2135	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.4238
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	265.244
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63866
PMC8716518__F11	PFOCR Pathway Figure Associations 2024	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.71515
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.15642
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33151
SRSF6	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEXIM2	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EM-2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.69635
HCC1395_BREAST	CCLE Cell Line Proteomics	1.0	2.13214
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLO1	DepMap CRISPR Gene Dependency	1.0	2.08426
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
HNRNPAB	Pathway Commons Protein-Protein Interactions	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
RUNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2647
SRPR	Pathway Commons Protein-Protein Interactions	1.0	null
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
Mitochondrial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.941
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10881
ZBTB33_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201735_3_v_1_cdca7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
EIF3L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL7	Pathway Commons Protein-Protein Interactions	1.0	null
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14848
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00147
decreased sensitivity to induced cell death	MPO Gene-Phenotype Associations	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99095
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17266
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142686
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879827
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00753
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.364
AA-62-HP31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286034
IGF2BP2	Pathway Commons Protein-Protein Interactions	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.944426
MRPS28	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.876878
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.999709
PMC11166884-mmc4.xlsx-Table_S3-Table_S3_proinflammatory-EC2_comparison_between_WT_and_TG_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.9076
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2407
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08769
143B	DepMap CRISPR Gene Dependency	1.0	2.09614
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993641
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17948
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
embryonic lethality	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CASC5	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935234
HIST3H3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2D	Pathway Commons Protein-Protein Interactions	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041932
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
MRPS12	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27774
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50238
ZBTB33_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS2	Pathway Commons Protein-Protein Interactions	1.0	null
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
Glutamate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.677
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A6	Pathway Commons Protein-Protein Interactions	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12138
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09509
LDHA	Pathway Commons Protein-Protein Interactions	1.0	null
ACER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
abnormal cell proliferation	MPO Gene-Phenotype Associations	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mtdna	GeneRIF Biological Term Annotations	1.0	null
TRMT61A	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2145
CAPRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99653
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20218
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
GE-77-FY84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416901
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95688
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10145
UTP14A	Pathway Commons Protein-Protein Interactions	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.32896
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904157
NDUFS2	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03633
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50661
PIK3CA_knockdown_182_GSE46869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.19352
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
embryo tissue necrosis	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42347
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10919
Regulatory dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
MRPS18C	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190076_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10468
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82447
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29254
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FN1	Pathway Commons Protein-Protein Interactions	1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540455
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A	ChEA Transcription Factor Targets	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.33147
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.60927
ZC3H11A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49712
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942586
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF33B	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27807
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302325
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994278
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21173
nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225267
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.39724
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28116
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41412
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
ABCB8	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876989
L-5178-Y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
RPP30	Pathway Commons Protein-Protein Interactions	1.0	null
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS26	Pathway Commons Protein-Protein Interactions	1.0	null
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36813
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.40173
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92403
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055334
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Hereditary spastic paraplegia 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17098
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	2.21564
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214091
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07673
KPL1	DepMap CRISPR Gene Dependency	1.0	2.19803
GSE89569_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A10	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55099
MCF7_Droxinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157194
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.092974
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991277
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61225
MAGT1	Pathway Commons Protein-Protein Interactions	1.0	null
Pollen coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943007
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.619
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887037
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4609
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TRMT112	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1564
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913193
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241891
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15989
MRPS24	Pathway Commons Protein-Protein Interactions	1.0	null
K562_EED226_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221175
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81807
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21569
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866906
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50116
SKIV2L2	Pathway Commons Protein-Protein Interactions	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056171
SMU1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4385866__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22364
H3F3A	Pathway Commons Protein-Protein Interactions	1.0	null
ZC3H4	Pathway Commons Protein-Protein Interactions	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05695
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6401-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.918234
JEKO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.90268
EIF4B	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ESYT1	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56288
MRPS34	Pathway Commons Protein-Protein Interactions	1.0	null
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873882
NCIH2196	CCLE Cell Line Gene Expression Profiles	-1.0	-3.09273
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14537
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853521
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947356
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NOP56	Pathway Commons Protein-Protein Interactions	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Inflorescence apex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.64
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4424
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.4546
POLR1A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7980-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL20	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58352
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93206
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25376
AIFM1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX30	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12561
POLR2E	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859201
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11054
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.496175
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal cell death	MPO Gene-Phenotype Associations	1.0	null
RV16_0Hour-B2B_None_GSE28904	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.30575
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS5	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.77183
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.535
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
translation	GO Biological Process Annotations 2015	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061866
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938124
cellular component biogenesis	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0237846
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04133
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TASK1	DepMap CRISPR Gene Dependency	1.0	2.16942
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BIN67	DepMap CRISPR Gene Dependency	1.0	2.37555
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.849256
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.581
4147_INTS2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.624678
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824056
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05013
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16005
maintenance	GeneRIF Biological Term Annotations	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24682
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19147
MRPL19	Pathway Commons Protein-Protein Interactions	1.0	null
SUP-B15	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.64872
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841882
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01161
EJM	CCLE Cell Line Gene Expression Profiles	1.0	1.61209
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17074
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05529
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38062
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25738
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875692
FTC238	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95343
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADNP_Deficiency - NULL MUTATION_GDS2540_692_mouse_E9 embryos - Homozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
FAM98A	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.205
Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LAD1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SOX15	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCCC2	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mcf-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.380627
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32031
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08457
ICT1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18203
ATP5A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917659
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09914
Chloroplast nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.482
regulation of cellular respiration	GO Biological Process Annotations 2015	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Sodium Phenylbutyrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133517
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07169
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950256
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62274
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.451
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40837
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64585
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872408
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
SERBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23137
Cerebrooculofacioskeletal syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62462
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0954
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00678
ELK1	ENCODE Transcription Factor Targets	1.0	null
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
FAM98B	Pathway Commons Protein-Protein Interactions	1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.55993
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90019
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CP50-MEL-B	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.04962
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53393
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95259
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893966
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.9187
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.371
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33073
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NOB1	Pathway Commons Protein-Protein Interactions	1.0	null
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
PUS1	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30048
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1869
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YBX3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199606_2_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62837
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SARS-BatSRBD_72Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.06213
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	2.31467
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41317
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.893463
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943109
S100A10	Pathway Commons Protein-Protein Interactions	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833308
CCDC88C	Pathway Commons Protein-Protein Interactions	1.0	null
RNMT	Pathway Commons Protein-Protein Interactions	1.0	null
BEX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05358
LSG1	Pathway Commons Protein-Protein Interactions	1.0	null
SNRPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91388
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17157
MRPS7	Pathway Commons Protein-Protein Interactions	1.0	null
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.24
MZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88935
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.0102
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66953
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GRB10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835334
A-CA-04-2009(H1N1)_48Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.34262
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
regulation of cellular respiration	GO Biological Process Annotations 2023	1.0	null
LSM2	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1707
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.951847
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321426
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24785
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230867
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53245
SW948	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.3544
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OS-RC-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.88091
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTP binding	GO Molecular Function Annotations 2025	1.0	null
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35218
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIST1H1E	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52025
A1CF	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03143
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRPB2	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76041
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919424
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26878
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890898
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
decreased sensitivity to induced cell death	MGI Mouse Phenotype Associations 2023	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23246
PUSL1	Pathway Commons Protein-Protein Interactions	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5118
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
NHP2L1	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33868
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84912
Calcium	CTD Gene-Chemical Interactions	1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54269
PTCD3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928883
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.469
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05835
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL14	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69018
Alveolar cell type II	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
Plastid envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.23815
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IK	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2666-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00258
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930787
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZZ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LONP1	Pathway Commons Protein-Protein Interactions	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.6206
MRPL4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.131
abnormal cell physiology	MGI Mouse Phenotype Associations 2023	1.0	null
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
5205_MRPL21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.618158
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984986
GC-74-QF56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34428
JUND	ENCODE Transcription Factor Targets	1.0	null
Wet Macular Degeneration	HuGE Navigator Gene-Phenotype Associations	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896057
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495598
extrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993216
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9656_USP39_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.707699
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS31	Pathway Commons Protein-Protein Interactions	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32771
MOV10	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269174
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09923
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844055
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40324
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04525
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942422
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935957
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955857
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Acn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.235
THNSL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.469
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
SF3B4	Pathway Commons Protein-Protein Interactions	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.70291
mitochondrial ribosome assembly	GO Biological Process Annotations 2023	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879294
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02991
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15565
LETM1	Pathway Commons Protein-Protein Interactions	1.0	null
PKP3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193354_0_v_1_saraf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP5F1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.566032
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USP7	Pathway Commons Protein-Protein Interactions	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10966
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRSF1	Pathway Commons Protein-Protein Interactions	1.0	null
UTP3	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRPD1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50455
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01135
NCI-H1436	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.76846
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998232
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
HMGN3	ENCODE Transcription Factor Targets	1.0	null
abnormal apoptosis	MPO Gene-Phenotype Associations	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79051
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919697
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31818
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998232
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183101_0_v_1_hvcn1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1075-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6433273-pone.0214296.s009.xlsx-Table_D-S4_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_24_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.929219
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A1	Pathway Commons Protein-Protein Interactions	1.0	null
BL41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78157
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARS CoV_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66877
Necrosis	CTD Gene-Disease Associations	1.0	1.20295
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HEXIM1	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11748
DKC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841093
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0904
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL10	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JJN-3	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-6.42654
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
Cytoplasmic exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.443
Auxin efflux carrier complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887513
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7401
BPNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27341
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33198
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82302
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL26L1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844383
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
KRI1	Pathway Commons Protein-Protein Interactions	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16038
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.552
NSUN2	Pathway Commons Protein-Protein Interactions	1.0	null
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
UFL1	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34587
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
PMC12461113-HEM3-9-e70217-s002.xlsx-Table_S3-Model_1_top_50_genes_IKZF5_IKZF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.487
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29444
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZEB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054063
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.11513
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45919
Prostate adenocarcinoma_PRAD_TCGA-CH-5764-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inflorescence stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
ARF1	Hub Proteins Protein-Protein Interactions	1.0	null
RSL1D1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.96139
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOP16	Pathway Commons Protein-Protein Interactions	1.0	null
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46847
GTP binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26555
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL49	Pathway Commons Protein-Protein Interactions	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955857
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1926
WM1799	DepMap CRISPR Gene Dependency	1.0	2.34153
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	2.08298
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUC7L2	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1568
MRPL55	Pathway Commons Protein-Protein Interactions	1.0	null
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884449
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00575
MRPL15	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72719
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843433
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253202
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16996
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-81-VY50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263364
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41765
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.854873
LARS	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923275
SFXN1	Pathway Commons Protein-Protein Interactions	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26585
liver	GTEx Tissue Gene Expression Profiles	-1.0	-2.10019
NR2C2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30433
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27912
Perturb_4525_KO_Chaf1a_ERP006640	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.63442
KC-32-GO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244416
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83512
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrial ribosome assembly	GO Biological Process Annotations 2025	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059594
NMB	DepMap CRISPR Gene Dependency	1.0	2.25307
membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
abnormal prenatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
KMS34	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34373
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.56841
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21695
hsa-miR-197-3p	MiRTarBase microRNA Targets	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.029
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF_KO_GDS3732_148_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPS18A	Pathway Commons Protein-Protein Interactions	1.0	null
HEK-293F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03237
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.871651
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269129
MCF7_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110561
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7623
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89435
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.76986
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20219
RPL36	Pathway Commons Protein-Protein Interactions	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948944
NDUFS8	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57698
Leaf primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EIF3C	Pathway Commons Protein-Protein Interactions	1.0	null
RPN1	Pathway Commons Protein-Protein Interactions	1.0	null
cSARS Bat SRBD_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.97132
CDK2AP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1148
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AURKA_druginhibition_196_GSE57810	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.10542
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977535
PRPF6	Pathway Commons Protein-Protein Interactions	1.0	null
breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161331
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01109
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01073
Lung squamous cell carcinoma_LUSC_TCGA-39-5016-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22455
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11745
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4759-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01073
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.541645
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17334
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4412
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44454
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33553
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07538
HNRNPUL2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84052
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS23	Pathway Commons Protein-Protein Interactions	1.0	null
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387587
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870557
A-CA-04-2009(H1N1)_6Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.4632
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12851
GLUD1	Pathway Commons Protein-Protein Interactions	1.0	null
IMP3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0826-SM-3P61K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94833
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27807
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10868
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04259
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17013
MRPL22	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.925
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Flavopiridol HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159789
SLTM	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL2	Pathway Commons Protein-Protein Interactions	1.0	null
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15553
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Flavopiridol HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0103001
KE39	DepMap CRISPR Gene Dependency	1.0	2.35419
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAFB2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chloroplast ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.456
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16745
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV_84Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40002
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289535
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22969
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42386
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0481
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933378
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45099
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17684
EIF2S1	Pathway Commons Protein-Protein Interactions	1.0	null
CD3EAP	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23016
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64692
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.22748
RPL17	Pathway Commons Protein-Protein Interactions	1.0	null
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05827
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245793
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
EOL1	DepMap CRISPR Gene Dependency	1.0	2.28584
EIF3E	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1B2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235141
LSM14A	Pathway Commons Protein-Protein Interactions	1.0	null
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.6478
KDM5B	ENCODE Transcription Factor Targets	1.0	null
LS123	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85642
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	2.06332
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POP5	Pathway Commons Protein-Protein Interactions	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02181
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864385
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28224
A2780	DepMap CRISPR Gene Dependency	1.0	2.11916
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291764
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73624
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35523
POLRMT	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.77038
Lung squamous cell carcinoma_LUSC_TCGA-43-2578-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Root pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948432
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843879
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EIF3K	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96968
Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC8494348-pone.0257161.s002.xlsx-only_OXT_NOT_ext-OXT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3D	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.575
plastid-encoded plastid RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.142
Mpk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
JR	DepMap CRISPR Gene Dependency	1.0	2.29792
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056909
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.700507
decreased apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061321
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6223
MCU	Pathway Commons Protein-Protein Interactions	1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42725
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
C80	DepMap CRISPR Gene Dependency	1.0	2.24719
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81057
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
Ventilator-associated lung injury_Lung Tissue_GSE2411	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.76537
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37465
RPS29	Pathway Commons Protein-Protein Interactions	1.0	null
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.68068
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367456
cytoplasmic chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.231315
RPS4Y2	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58814
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8593586-mmc2.xlsx-LIN28A_interactome-Unnamed_1_LIN28A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06566
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31526
Ammonium transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELP4	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.925831
PHF5A	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07603
DDX47	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF15	Pathway Commons Protein-Protein Interactions	1.0	null
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.254
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.347
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16159
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59556
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCT15	DepMap CRISPR Gene Dependency	1.0	2.10516
CHTF18	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHC2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13103
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04532
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFO-21	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.13026
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JVM3	DepMap CRISPR Gene Dependency	1.0	2.42478
TOP1	Pathway Commons Protein-Protein Interactions	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
Enalapril	CTD Gene-Chemical Interactions	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52155
POU5F1	ChEA Transcription Factor Targets	1.0	null
Periderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.884199
USF2	ENCODE Transcription Factor Targets	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	2.28013
STAT1	ENCODE Transcription Factor Targets	1.0	null
KPNA2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0054
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
U251MG	CCLE Cell Line Gene CNV Profiles	1.0	2.05464
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5170-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAD9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907862
K562_MK-5108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159564
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SHMT2	Pathway Commons Protein-Protein Interactions	1.0	null
POLDIP3	Pathway Commons Protein-Protein Interactions	1.0	null
RPL6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964657
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043494
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1444
USP10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4177-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19919
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206747
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM42	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
UQCRC1	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36857
mitochondrion organization	GO Biological Process Annotations 2015	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063918
PMC11746978-41598_2025_86316_MOESM2_ESM.xlsx-sheet2-Only_MR_or_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AIMP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDX23	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mitochondrial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.021
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83381
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP5C1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23872
MCF7_PFI-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157774
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0676
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40424
ZFP91	Pathway Commons Protein-Protein Interactions	1.0	null
TOPAZ1	Pathway Commons Protein-Protein Interactions	1.0	null
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
molt4	HPA Cell Line Gene Expression Profiles	1.0	1.0584
MRPS23	Pathway Commons Protein-Protein Interactions	1.0	null
K562_BRD4770_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196716
MGME1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968958
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
MICU2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57035
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4176-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03639
GATA1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
rectum	HPA Tissue Protein Expression Profiles	1.0	0.925831
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.094825
MAFF	ENCODE Transcription Factor Targets	1.0	null
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39041
AIMP2	Pathway Commons Protein-Protein Interactions	1.0	null
NMC-G1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.02788
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50749
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825537
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886846
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SBC5	CCLE Cell Line Gene CNV Profiles	1.0	1.67088
JAK1_activemutant_61_GSE18239	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.60984
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00208
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67562
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60579
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chr4_56853600_A_C_b38	GTEx eQTL 2025	1.0	1.06119
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58604
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX54	Pathway Commons Protein-Protein Interactions	1.0	null
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.39051
LDHB	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050858
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203184
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9493
skin	GTEx Tissue Gene Expression Profiles	1.0	0.852483
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.36094
NOLC1	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Ki8751_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210438
YME1L1	Pathway Commons Protein-Protein Interactions	1.0	null
DBR1	Pathway Commons Protein-Protein Interactions	1.0	null
PSPC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cytochrome-c oxidase deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
SLIRP	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994539
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11833
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.61957
LAMA5	Pathway Commons Protein-Protein Interactions	1.0	null
Cytosolic ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893938
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.09818
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGB3	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11629966-btae696_supplementary_data.docx-18-FOSL2_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HK1	Pathway Commons Protein-Protein Interactions	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06396
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
RPL19	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal mitochondrial crista morphology	MGI Mouse Phenotype Associations 2023	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9307
mitochondrion organization	GO Biological Process Annotations 2025	1.0	null
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26707
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.05497
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98643
ZBTB33_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OC-71-BZ81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230988
ATP5H	Pathway Commons Protein-Protein Interactions	1.0	null
STRAP	Pathway Commons Protein-Protein Interactions	1.0	null
t-cell chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29253
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51045
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888874
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal respiratory electron transport chain	MPO Gene-Phenotype Associations	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71903
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88288
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Micropyle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
PMC7833686-mmc5.xlsx-e_q1en30_v1-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44309
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03121
MCC142	DepMap CRISPR Gene Dependency	1.0	2.0928
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
A375SKINCJ2	DepMap CRISPR Gene Dependency	1.0	2.00105
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04095
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GUF1	Pathway Commons Protein-Protein Interactions	1.0	null
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863213
MMAB	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL13	Pathway Commons Protein-Protein Interactions	1.0	null
Peroxynitrous Acid	CTD Gene-Chemical Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65761
2613_EMC3_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.525352
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13289
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
LUC7L	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493407
LYAR	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_CVGBM-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	1.49607
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08102
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ST486	DepMap CRISPR Gene Dependency	1.0	2.0381
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-2.18484
PMC5806898-pbio.2004411.s003.xlsx-MR_plot_data-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02807
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5152
CBX6	Pathway Commons Protein-Protein Interactions	1.0	null
GADD45GIP1	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of generation of precursor metabolites and energy	GO Biological Process Annotations 2023	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841897
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15793
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953399
PEG10	Pathway Commons Protein-Protein Interactions	1.0	null
NOP14	Pathway Commons Protein-Protein Interactions	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212856
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3273
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10441
abnormal mitochondrial inner membrane morphology	MPO Gene-Phenotype Associations	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ULK2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16619
Rosette	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85371
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828086
MRPL51	Pathway Commons Protein-Protein Interactions	1.0	null
single-organism biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84968
PPP1R10	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SGPL1	Pathway Commons Protein-Protein Interactions	1.0	null
YARS2	Pathway Commons Protein-Protein Interactions	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6463
TBX5	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40654
cSARS Bat SRBD_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.08261
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2257
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52065
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3712200-584604.f1.pdf-43-THYN1_THYN1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OXA1L	Pathway Commons Protein-Protein Interactions	1.0	null
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TT	CCLE Cell Line Gene Expression Profiles	1.0	1.65566
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271359
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62105
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPLAD1	Pathway Commons Protein-Protein Interactions	1.0	null
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coronary artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.029
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82547
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PNPLA6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM29	Pathway Commons Protein-Protein Interactions	1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
decreased embryonic tissue cell apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASF1A	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855491
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fra-1_KO_GDS5078_403_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00349
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COL9A2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SYK_druginhibition_282_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.34811
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341739
mcf7	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim22_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SUPV3L1	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
PLK1	Pathway Commons Protein-Protein Interactions	1.0	null
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08189
CCDC86	Pathway Commons Protein-Protein Interactions	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998232
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86321
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954745
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
guanyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09026
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11635
TOX4	Pathway Commons Protein-Protein Interactions	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238967
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50176
PMC3807112-srep03041-s6.xls-E2F1-Gene_Symbol_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
PARP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877357
LN464	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89909
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.858027
MTIF2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.8847
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18655
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891192
MPP3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC2820517-pcbi.1000671.s006.txt--ZNF449_ZNF449	Rummagene Transcription Factor Associations 2026	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.55795
AARS2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIST1H1D	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159403
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00275
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2023	1.0	null
FASTKD2	Pathway Commons Protein-Protein Interactions	1.0	null
ADCK3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78284
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
RPS14	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T47D	DepMap CRISPR Gene Dependency	1.0	2.3601
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TDRD5	Pathway Commons Protein-Protein Interactions	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69665
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2716-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.673
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
LP1	CCLE Cell Line Gene Expression Profiles	1.0	1.39936
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27001
ribosome assembly	GO Biological Process Annotations 2025	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.99963
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.598351
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911054
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886277
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994851
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41367
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.25218
PMC3253802-pone.0029922.s001.pdf-116-ZBTB41_ZBTB41	Rummagene Transcription Factor Associations 2026	1.0	null
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.62263
AD-72-RI24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232844
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482038
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.817
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35414
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22352
Hsf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19191
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.929269
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL21	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.92676
Lung adenocarcinoma_LUAD_TCGA-55-7283-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
guanyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
abnormal trophoblast layer morphology	MPO Gene-Phenotype Associations	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH23	DepMap CRISPR Gene Dependency	1.0	2.27996
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47789
SSR4	Pathway Commons Protein-Protein Interactions	1.0	null
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323509
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114992,GSE114993_0_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08776
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40404
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07973
WSUDLCL2	CCLE Cell Line Gene Expression Profiles	1.0	1.35577
SREK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Endemic goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.95771
VDAC3	Pathway Commons Protein-Protein Interactions	1.0	null
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15817
EIF3I	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880257
POLR3A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11143964-jciinsight-9-161356-s009.pdf-15-ZNF841_ZNF841	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21176
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COL17A1	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04639
GSE142994_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00817
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50926
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991773
OCIAML3	DepMap CRISPR Gene Dependency	1.0	2.30489
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968034
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5
abnormal induced cell death	MPO Gene-Phenotype Associations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJA3	Pathway Commons Protein-Protein Interactions	1.0	null
RBM39	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29217
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840051
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE180	DepMap CRISPR Gene Dependency	1.0	2.45023
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069137
MYOG	ENCODE Transcription Factor Targets	1.0	null
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim29_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.77555
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4596691__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-01A-21R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18039
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE198165,GSE198166_9_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051345
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03995
DDX56	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07027
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34694
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232493
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38691
Medial cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcium	GeneRIF Biological Term Annotations	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588236
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39851
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37341
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
MRPL41	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08385
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
SLC25A18	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04937
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
8489_STARD3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.649275
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70022
FOSL2	ENCODE Transcription Factor Targets	1.0	null
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826696
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82422
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23544
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08085
MTPAP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84256
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-582-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WEE1_druginhibition_307_GSE38972	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.12837
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6525
POLR2H	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36103
NANOG	ChEA Transcription Factor Targets	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM1799_SKIN	CCLE Cell Line Proteomics	1.0	6.14232
NCAPD3	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal mitochondrial physiology	MPO Gene-Phenotype Associations	1.0	null
MRPL28	Pathway Commons Protein-Protein Interactions	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223137
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04304
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.01356
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866488
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221793
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901109
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_ZFP42_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H1F0	Pathway Commons Protein-Protein Interactions	1.0	null
CNOT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3256
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85896
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976469
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280717
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29148
ALYREF	Pathway Commons Protein-Protein Interactions	1.0	null
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
LAS1L	Pathway Commons Protein-Protein Interactions	1.0	null
NRF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.987391
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23156
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.835855
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456001
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7226
MCF7_Veliparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144682
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.40176
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.162094
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2994-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
HEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.93263
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.925831
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06749
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	2.08763
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058994
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.692699
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC3A2	Pathway Commons Protein-Protein Interactions	1.0	null
ERI1	Pathway Commons Protein-Protein Interactions	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
cell part	GO Cellular Component Annotations 2015	1.0	null
MRPL21	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of generation of precursor metabolites and energy	GO Biological Process Annotations 2015	1.0	null
matrix side of mitochondrial inner membrane	GO Cellular Component Annotations 2025	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11792
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8231_SNRPE_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.08447
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78603
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF3A3	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11575
PLCD3	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845466
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYO1	DepMap CRISPR Gene Dependency	1.0	2.45403
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TT1TKB	DepMap CRISPR Gene Dependency	1.0	2.35586
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57441
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11595
Perturb_8012_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.68585
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981282
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2S2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-CXCR3KO_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.22747
NCOR2	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01866
TRMT10C	Pathway Commons Protein-Protein Interactions	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.9115
KDM5B	ChEA Transcription Factor Targets	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5719
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948766
MCAT	Pathway Commons Protein-Protein Interactions	1.0	null
Pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.455
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03163
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
ATXN2L	Pathway Commons Protein-Protein Interactions	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48697
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSD17B4	Pathway Commons Protein-Protein Interactions	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534563
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47978
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283251
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
present	GeneRIF Biological Term Annotations	1.0	null
MARCKS	Pathway Commons Protein-Protein Interactions	1.0	null
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-dORF6_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.92719
MRPS10	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29302
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC6	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848778
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16538
Combined oxidative phosphorylation deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80129
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.58144
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.925831
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893966
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06567
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25163
CELF1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fungal-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
FOXM1	ENCODE Transcription Factor Targets	1.0	null
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2164
ZFP42	ChEA Transcription Factor Targets	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199081_0_v_1_insr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-17-CS60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305286
Lung squamous cell carcinoma_LUSC_TCGA-43-8118-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47823
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.825204
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	1.0	3.14801
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12045
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890264
MRM1	Pathway Commons Protein-Protein Interactions	1.0	null
adult testis	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-0.840971
PLOD3	Pathway Commons Protein-Protein Interactions	1.0	null
NUFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.709691
TR146	DepMap CRISPR Gene Dependency	1.0	2.17795
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEG3	Pathway Commons Protein-Protein Interactions	1.0	null
POP1	Pathway Commons Protein-Protein Interactions	1.0	null
HEC59	DepMap CRISPR Gene Dependency	1.0	2.22065
mitochondrial translation	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1122
PDK3	Pathway Commons Protein-Protein Interactions	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
HIST1H1B	Pathway Commons Protein-Protein Interactions	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39735
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05175
JAK2_activemutant_72_GSE21842	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.23913
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal mitochondrial atp synthesis coupled electron transport	MPO Gene-Phenotype Associations	1.0	null
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54254
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43342
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH157DM	DepMap CRISPR Gene Dependency	1.0	2.42393
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS27	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-889	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893966
SF3B2	Pathway Commons Protein-Protein Interactions	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.05104
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17884
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48229
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864244
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5153
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59473
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15989
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATIC	Pathway Commons Protein-Protein Interactions	1.0	null
A172	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.90093
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.900696
Inflammation	CTD Gene-Disease Associations	1.0	1.08904
Lateral root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD51C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.295
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHLA10	DepMap CRISPR Gene Dependency	1.0	2.28767
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833308
POLR2C	Pathway Commons Protein-Protein Interactions	1.0	null
Companion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
GTF2E2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84086
DDX1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8056
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2122_LUNG	CCLE Cell Line Proteomics	1.0	2.43614
CUX1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33158
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTRF	Pathway Commons Protein-Protein Interactions	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.954598
complete embryonic lethality during organogenesis	MPO Gene-Phenotype Associations	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5604
HMGB2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMG1	Pathway Commons Protein-Protein Interactions	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
UBAP2L	Pathway Commons Protein-Protein Interactions	1.0	null
RCH-ACV	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.14483
Lung squamous cell carcinoma_LUSC_TCGA-92-8064-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89676
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14297
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54903
monolayer-surrounded lipid storage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RECQL	Pathway Commons Protein-Protein Interactions	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040768
nitric	GeneRIF Biological Term Annotations	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26636
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06294
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17253
Mitochondrion	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metallochaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
Photosystem II antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.081
CSTF2	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60267
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17131
Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BPTF	Pathway Commons Protein-Protein Interactions	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
skbr3	HPA Cell Line Gene Expression Profiles	1.0	1.61453
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.917954
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14707
CLPX	Pathway Commons Protein-Protein Interactions	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10525
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ribosome biogenesis	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858367
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946311
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869514
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A3-KAW	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.82984
PMC8067372__F8	PFOCR Pathway Figure Associations 2023	1.0	null
Polyps	HuGE Navigator Gene-Phenotype Associations	1.0	null
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
SSBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10493
embryonic growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-CoV_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63718
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84547
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IGF2BP3	Pathway Commons Protein-Protein Interactions	1.0	null
EWSR1	Pathway Commons Protein-Protein Interactions	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30997
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62081
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068625
HN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32771
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03165
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42924
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.446182
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS578T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4807
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44218
abnormal embryonic growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.37849
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.43507
MOG-G-CCM	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.48268
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57874
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853677
TE11	DepMap CRISPR Gene Dependency	1.0	2.339
PANC0403	CCLE Cell Line Gene CNV Profiles	1.0	1.3388
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1051
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940361
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06434
TARS2	Pathway Commons Protein-Protein Interactions	1.0	null
MOGGCCM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64912
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826441
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.10304
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08609
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15178
AASS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3412-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS15A	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08169
subunit	GeneRIF Biological Term Annotations	1.0	null
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20743
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929866
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31551
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02476
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4G1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TBL2	Pathway Commons Protein-Protein Interactions	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15787
RUNX1	ChEA Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRPF19	Pathway Commons Protein-Protein Interactions	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
SW1783	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52788
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23156
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80714
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02422
NPLOC4	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA binding	GO Molecular Function Annotations 2023	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
U118MG_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	3.05516
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01073
Perturb_10437_Mut_Chek1_SRP299085	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.16689
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR3A	ENCODE Transcription Factor Targets	1.0	null
SERPINF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00653
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS15	Pathway Commons Protein-Protein Interactions	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33617
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35053
FASTKD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4492
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.925
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15158
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06131
A-CA-04-2009(H1N1)_6Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.94951
RPL7A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DDX28	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPL16	Pathway Commons Protein-Protein Interactions	1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47125
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1221
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.30705
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998232
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09811
Mucilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38673
BMS1	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861515
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5932-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63065
CSTF3	Pathway Commons Protein-Protein Interactions	1.0	null
K562	DepMap CRISPR Gene Dependency	1.0	2.26462
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832052
WM2664	DepMap CRISPR Gene Dependency	1.0	2.16719
CHCHD1	Pathway Commons Protein-Protein Interactions	1.0	null
ACVR2A	Kinase Library Serine Threonine Kinome Atlas	1.0	null
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.45768
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900483
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
DHCR24	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85439
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924353
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1428	DepMap CRISPR Gene Dependency	1.0	2.24088
MRPL17	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22232
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09134
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07508
MCF7_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130978
death	GO Biological Process Annotations 2015	1.0	null
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06978
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS22	Pathway Commons Protein-Protein Interactions	1.0	null
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	1.87978
PRPF4	Pathway Commons Protein-Protein Interactions	1.0	null
Storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18946
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56614
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28214
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21237
Inositol phosphoceramide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904157
ZFP42-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27458
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
NOC4L	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.829588
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13159
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09198
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16298
PMC5214989__F2	PFOCR Pathway Figure Associations 2024	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03083
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Breast 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-6.34036
SARS-CoV_96Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.067
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985419
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11148
decreased cell proliferation	MPO Gene-Phenotype Associations	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0454
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.939
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227771
programmed cell death	GO Biological Process Annotations 2015	1.0	null
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS14	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.645
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PRPF8	Pathway Commons Protein-Protein Interactions	1.0	null
HKDC1	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34957
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FXR1	Pathway Commons Protein-Protein Interactions	1.0	null
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6711
SPI1	ChEA Transcription Factor Targets	1.0	null
Scutellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
MRPL18	Pathway Commons Protein-Protein Interactions	1.0	null
P4E6	DepMap CRISPR Gene Dependency	1.0	2.32017
AUH	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AE-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1072
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTPBP10	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1571
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.139452
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41025
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34319
NDUFAF3	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPLL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87439
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0567
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8188
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923081
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8553
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
KNS42	CCLE Cell Line Gene Expression Profiles	-1.0	-2.96455
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10237
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL32	Pathway Commons Protein-Protein Interactions	1.0	null
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28689
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.787213
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40976
RPS9	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.830244
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204948
PMC2965092-pone.0013658.s001.xls-Liangos_SOM_Table1-GeneName_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334694
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065825
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.85272
U2SURP	Pathway Commons Protein-Protein Interactions	1.0	null
Perrault syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8661_TAF1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	2.36008
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUCLA2	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25507
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68438
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE146982_3_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875074
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.12605
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV3_OVARY	CCLE Cell Line Proteomics	1.0	2.35883
RERFLCAI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6468
NRF1	JASPAR Predicted Transcription Factor Targets	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MRPL46	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UG-01A-32R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35368
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.4404
small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.745025
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.62205
AIM1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_15_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92001
MRPL12	Pathway Commons Protein-Protein Interactions	1.0	null
trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.54132
THBS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMPCA	Pathway Commons Protein-Protein Interactions	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50679
nucleoside-triphosphatase activity	GO Molecular Function Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916603
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06132
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHERP	Pathway Commons Protein-Protein Interactions	1.0	null
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.815
RPL27	Pathway Commons Protein-Protein Interactions	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21781
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11966
7185_RBM8A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.722896
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01458
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63931
DDX46	Pathway Commons Protein-Protein Interactions	1.0	null
CCAR1	Pathway Commons Protein-Protein Interactions	1.0	null
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83739
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66317
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65142
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NIPSNAP1	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
YTHDF3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10956
GVINP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03793
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041325
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03985
GTEx Vagina 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-3.11128
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3367-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_Name_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.348
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829261
MRPL10	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NADPH oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.756
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41088
MRPL43	Pathway Commons Protein-Protein Interactions	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14227
Egg chorion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08411
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.621998
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.32753
PMC5214989__F2	PFOCR Pathway Figure Associations 2023	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8513
YTHDF2	Pathway Commons Protein-Protein Interactions	1.0	null
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL37	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228784
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944712
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
Mitochondrial ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.459
MIAPACA2	DepMap CRISPR Gene Dependency	1.0	2.39027
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35232
AE-06-FY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381475
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.719
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904245
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993584
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17430594-tableS3	GeneSigDB Published Gene Signatures	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17769
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05835
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inferior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26341
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838988
EIF2S3	Pathway Commons Protein-Protein Interactions	1.0	null
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.998
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14188
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060862
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874439
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4803-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NELFB	Pathway Commons Protein-Protein Interactions	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	2.28073
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205495
SYO1	DepMap CRISPR Gene Dependency	1.0	2.41145
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.884199
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CNP	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6611_PPAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.864967
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255680_2_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.618
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67977
Spinocerebellar ataxia type 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06659
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21715
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90882
CB-82-PL01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217838
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5O	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNL2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTG1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.968329
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85376
GEMIN5	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrial membrane part	GO Cellular Component Annotations 2015	1.0	null
GTF3C1	Pathway Commons Protein-Protein Interactions	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.421035
apoptosis	GeneRIF Biological Term Annotations	1.0	null
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
Mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6474
envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K27ac_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
organelle organization	GO Biological Process Annotations 2025	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993584
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24484
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00047
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949696
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUPT5H	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX18	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrial inner membrane	GO Cellular Component Annotations 2025	1.0	null
AGBL1	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR1C	Pathway Commons Protein-Protein Interactions	1.0	null
OCIAML2	DepMap CRISPR Gene Dependency	1.0	2.35946
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	2.28247
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7891
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
8222_SNRNP70_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.39359
NDUFS3	Pathway Commons Protein-Protein Interactions	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	1.0	1.73717
organelle organization	GO Biological Process Annotations 2023	1.0	null
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.3939
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904157
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_downregulated-Genes_downregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22735
PPIL4	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59003
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07355
CHUK_knockdown_108_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.64343
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117727
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
MTDH	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82412
Lung squamous cell carcinoma_LUSC_TCGA-85-8354-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_2_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
4908_MCOLN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.598041
Leaf vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CCND1	ChEA Transcription Factor Targets	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969972
ISTMES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03761
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HPSE	Pathway Commons Protein-Protein Interactions	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22869
GSE112762,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF483	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04666
Cancer of prostate_Prostate_GSE1413	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.44427
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
RPS17	Pathway Commons Protein-Protein Interactions	1.0	null
GLTSCR2	Pathway Commons Protein-Protein Interactions	1.0	null
PHA granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DRG1	Pathway Commons Protein-Protein Interactions	1.0	null
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22549
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10931
VARS2	Pathway Commons Protein-Protein Interactions	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plant cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964584
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BOK	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.442
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220991
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283786
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55794
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966254
NMT1	Pathway Commons Protein-Protein Interactions	1.0	null
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833308
SCLC21H	CCLE Cell Line Gene Expression Profiles	1.0	1.7564
NAP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5942
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.09751
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60651
MRPS11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.04107
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01423
HIST1H2BB	Pathway Commons Protein-Protein Interactions	1.0	null
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.28568
cone-rod dystrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BF-26-MB27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282519
SBC-5	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.74131
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61054
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20759
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16255
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937119
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNMT1	Pathway Commons Protein-Protein Interactions	1.0	null
RBM12	Pathway Commons Protein-Protein Interactions	1.0	null
DDX3Y	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970149
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.241
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136552
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1673
POLR2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943579
guanyl ribonucleotide binding	GO Molecular Function Annotations 2025	1.0	null
Response to bleomycin (chromatid breaks)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPSF2	Pathway Commons Protein-Protein Interactions	1.0	null
Transcription export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RPS3A	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal cellular respiration	MPO Gene-Phenotype Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862431
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08128
NCO2	DepMap CRISPR Gene Dependency	1.0	2.04807
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79565
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89129
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NN-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC59	Pathway Commons Protein-Protein Interactions	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.535029
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45802
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06048
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859084
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25818
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-2.04534
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.938
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08197
SF3B5	Pathway Commons Protein-Protein Interactions	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.915916
FUS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
A_CA_04_2009_7dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.28777
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
PMC3807112-srep03041-s6.xls-GABPA-Gene_Symbol_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
COX4I1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045256
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.73075
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330706
MAZ	ENCODE Transcription Factor Targets	1.0	null
ESYT2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
breast adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.501527
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956887
ZNF346	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
46 XX gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911595
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MCF7_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115312
GRPEL1	Pathway Commons Protein-Protein Interactions	1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29658
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232029
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial small ribosomal subunit	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-3615-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06818
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12294
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-dORF6_24Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.895228
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.864469
TMPO	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
gtp binding	GO Molecular Function Annotations 2015	1.0	null
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882585
RPSA	Pathway Commons Protein-Protein Interactions	1.0	null
THRAP3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.911182
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16365
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.35676
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10975175__F2	PFOCR Pathway Figure Associations 2024	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.62488
RFC4	Pathway Commons Protein-Protein Interactions	1.0	null
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
UBA52	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827466
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10026
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22555
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975672
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683305
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8687
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40132
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
ATP5L	Pathway Commons Protein-Protein Interactions	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829916
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.947173
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28121
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51165
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
HNRNPH3	Pathway Commons Protein-Protein Interactions	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	2.01502
MED1	Pathway Commons Protein-Protein Interactions	1.0	null
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30816
A673	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60694
SSB	Pathway Commons Protein-Protein Interactions	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893966
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44309
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
PTBP3	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
ABCB7	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55406
SLC35C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23461
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL4	Pathway Commons Protein-Protein Interactions	1.0	null
VDAC1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2744-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMRC20_KIDNEY	CCLE Cell Line Proteomics	1.0	2.21038
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962917
BYSL	Pathway Commons Protein-Protein Interactions	1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912043
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884527
autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.21974
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852483
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
NFYB	ENCODE Transcription Factor Targets	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.43665
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
A549_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139012
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00024
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RB-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26956
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.88265
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAR1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL35	Pathway Commons Protein-Protein Interactions	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	Pathway Commons Protein-Protein Interactions	1.0	null
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08083
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07026
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.13704
MCF7_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129008
PRDX5	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824284
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stigma papilla	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04314
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04453
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.780933
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44439
Mean spheric corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
GTEX-T6MO-0326-SM-32QOK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983359
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13823
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HSD17B10	Pathway Commons Protein-Protein Interactions	1.0	null
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16058
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.874205
HTATSF1	Pathway Commons Protein-Protein Interactions	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERAL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
embryonic lethality during organogenesis, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
oxide	GeneRIF Biological Term Annotations	1.0	null
DECR1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03145
GSE129402,GSE129405_1_v_0_tcf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8231
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959596
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46087
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09923
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511348
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904157
E2F3_KD_GDS4094_448_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37527
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498403
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.871302
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central gray substance of midbrain, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993307
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.925831
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
Rosette leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.313
GSE150634_1_v_0_cd28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
DCTPP1	Pathway Commons Protein-Protein Interactions	1.0	null
DB	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.80055
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54397
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86447
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06434
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.24779
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16094
regulation of cell death	GO Biological Process Annotations 2023	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835738
MRPL3	Pathway Commons Protein-Protein Interactions	1.0	null
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.23056
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913919
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrophosphatase activity	GO Molecular Function Annotations 2015	1.0	null
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACADVL	Pathway Commons Protein-Protein Interactions	1.0	null
Thymus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.527
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.453
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.673
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097058
16081686-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLDC	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086645
Mitochondrial prohibitin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.126
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SND1	Pathway Commons Protein-Protein Interactions	1.0	null
SKES1_BONE	CCLE Cell Line Proteomics	1.0	2.30991
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70228
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18343
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5976-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.528227
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28433
SW1783	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
EPRS	Pathway Commons Protein-Protein Interactions	1.0	null
ZFR	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrial part	GO Cellular Component Annotations 2015	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41164
MRPS16	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19263
PES1	Pathway Commons Protein-Protein Interactions	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
MRPS30	Pathway Commons Protein-Protein Interactions	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
Root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.864
FBL	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5942-01A-21R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFB2M	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM192A_BREAST	CCLE Cell Line Proteomics	1.0	2.86601
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GAR1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4870-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNL3	Pathway Commons Protein-Protein Interactions	1.0	null
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.694
TRA2B	Pathway Commons Protein-Protein Interactions	1.0	null
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.198
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01718
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3436-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12432
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.05255
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85926
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12193
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.28479
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.43355
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31318
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRWD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146687_2_v_1_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16024
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.01446
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939872
Lung squamous cell carcinoma_LUSC_TCGA-85-8351-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
LIG3	Pathway Commons Protein-Protein Interactions	1.0	null
extrinsic component of organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR3A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09776
ZNF33A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF20B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL5	Pathway Commons Protein-Protein Interactions	1.0	null
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271129
CREB1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.368
GTF2B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870189
Acquired Immunodeficiency Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84964
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40409
SNRPD3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922293
ZBTB33_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3436
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU175	CCLE Cell Line Gene Expression Profiles	1.0	1.45851
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81683
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37622
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834947
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881487
MRPL44	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.780031
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPA0	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897311
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.925831
MCF7_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00904668
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTRH2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932614
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922224
RNF2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTCD1	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58734
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01093
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83739
Leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.029
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041618
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PK-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.897643
POLR2A	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Nitrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77252
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SBC5	CCLE Cell Line Gene Expression Profiles	1.0	1.42005
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838659
TIAL1	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2172	DepMap CRISPR Gene Dependency	1.0	2.19389
NDUFV1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35352
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20646
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09391
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30432
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.925
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837654
HNRNPDL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14205
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM17	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DARS	Pathway Commons Protein-Protein Interactions	1.0	null
EAhy 926 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
DHX16	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5079
MRPS6	Pathway Commons Protein-Protein Interactions	1.0	null
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353052
SNRPC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCAS2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EIF3G	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSBP1	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24165
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HSPA8	Hub Proteins Protein-Protein Interactions	1.0	null
FUBP3	Pathway Commons Protein-Protein Interactions	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.10362
WBSCR16	Pathway Commons Protein-Protein Interactions	1.0	null
MYCN	ChEA Transcription Factor Targets	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.62959
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369382
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.977015
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17834
TIMM21	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6138936-13059_2018_1512_MOESM2_ESM.xlsx-SE_H1-_MSC-Gene-symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68397
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29558
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29119
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55009
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Spongiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36111
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.35733
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3322-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.90243
WB-82-EL69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288318
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
SART1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISCA1	Pathway Commons Protein-Protein Interactions	1.0	null
TRUB2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO818	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7178
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.29876
RPL27A	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrial inner membrane	GO Cellular Component Annotations 2023	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8335-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
apoptotic process	GO Biological Process Annotations 2015	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72093
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858728
T-cell chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867518
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2989
H3K79me2_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893966
RBM3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	1.94604
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BH-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96157
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956688
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057563
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00623
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7318
Root apex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.557
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913581
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
fh4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
LYZ	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16441
Wolff-Parkinson-White syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980486
AP2M1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDRGK1	Pathway Commons Protein-Protein Interactions	1.0	null
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840019
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HNRNPA1	Pathway Commons Protein-Protein Interactions	1.0	null
16622258-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
MRPS35	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.911182
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.225
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911949
K562_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017407
AE-88-WQ63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3135
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6014
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38262
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879149
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844717
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04262
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849775
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92334
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29125
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84254
CHD1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03152
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875307
RPUSD4	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40866
MRPL9	Pathway Commons Protein-Protein Interactions	1.0	null
MTFMT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922608
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERCC6L2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910364
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
FTC238	CCLE Cell Line Gene Expression Profiles	-1.0	-2.56189
Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93254
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NZM42	DepMap CRISPR Gene Dependency	1.0	2.01258
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_druginhibition_281_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.27226
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15699
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.883151
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TCF12	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Age-related macular degeneration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93X-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07032
KASUMI1	CCLE Cell Line Gene CNV Profiles	1.0	1.67737
FEN1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892105
TMEM214	Pathway Commons Protein-Protein Interactions	1.0	null
CIRBP	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Myocardial infarction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.029
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3807112-srep03041-s6.xls-ELK4-Gene_Symbol_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL18	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL50	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6500_KD_circSMO_SRP277579	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RBM27	Pathway Commons Protein-Protein Interactions	1.0	null
NELFE	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL40	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
TJP1	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72901
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916586
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
PMC3076323-pone.0018064.s016.xls-MYCN_targets_Marson_GSE6007-Unnamed_1_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06961
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.929151
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490308
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13021
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0591
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998232
CHD1	ENCODE Transcription Factor Targets	1.0	null
BL1040 (QKI)	NURSA Protein Complexes	1.0	null
CEP135	Pathway Commons Protein-Protein Interactions	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57035
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00343
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DA-81-VY50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29164
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.86948
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32205
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
TD-48-XJ84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319094
rna binding	GO Molecular Function Annotations 2015	1.0	null
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.28684
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17266
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60908
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ME2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.05704
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.474
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCCB	Pathway Commons Protein-Protein Interactions	1.0	null
extrinsic component of mitochondrial inner membrane	GO Cellular Component Annotations 2015	1.0	null
IFI16	Pathway Commons Protein-Protein Interactions	1.0	null
POU2F1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047186
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNO1	Pathway Commons Protein-Protein Interactions	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27807
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31062
RRS1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1568_LUNG	CCLE Cell Line Proteomics	1.0	2.44789
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07445
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10255
MRPL54	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBY-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.451978
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
Chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
6845_PSMA5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.573862
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06102
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04481
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPUSD3	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10709143-41556_2023_1271_MOESM7_ESM.xls-PAX7_Re-injury-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.937275
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229778
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11062
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIAML5	CCLE Cell Line Gene Expression Profiles	1.0	1.40613
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.586626
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5225
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60525
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CPSF1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17819
GATA4	ChEA Transcription Factor Targets	1.0	null
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
Sorsby's fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16189
SW962	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.4744
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08338
mitochondrial chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232029
Mitochondrial encephalomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
DPY30	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11225
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04259
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-97-KP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280436
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.09767
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833465
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6010-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10131
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15623
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22507
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0448
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227263
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53274
SAP30	ENCODE Transcription Factor Targets	1.0	null
MRPL48	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-79-ZF28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526854
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.699
MAX	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17284
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03556
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.05092
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
cell death	GO Biological Process Annotations 2015	1.0	null
TMEM109	Pathway Commons Protein-Protein Interactions	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
biogenesis	GeneRIF Biological Term Annotations	1.0	null
RPL26	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4993
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09176
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28066
D-283MED	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.77148
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.568
rvp3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29284
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.974748
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.7449
C10orf2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.78541
Lung adenocarcinoma_LUAD_TCGA-55-6986-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDLBP	Pathway Commons Protein-Protein Interactions	1.0	null
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
DNAJC13	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1_KO_GDS1511_251_mouse_Embryos at E12	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.423845
Bract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100652_PCx_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.278
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170652
NME4	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.39835
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	2.41704
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939803
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055144
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851728
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986159
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06434
HT	DepMap CRISPR Gene Dependency	1.0	2.42314
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051357
PRKCDBP	Pathway Commons Protein-Protein Interactions	1.0	null
RPL36A	Pathway Commons Protein-Protein Interactions	1.0	null
RANBP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890314
STAT3	ENCODE Transcription Factor Targets	1.0	null
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61621
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-359-NCOA1_NCOA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MET_knockout_259_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.95577
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC5889290-koni-07-04-1412909-s001.xlsx-GSC-exo_vs_Fibro-exo_stat_sign-Gene_name_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.091711
RRP12	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14647
569_ASB8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.637139
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.750098
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72085
regulating	GeneRIF Biological Term Annotations	1.0	null
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PECR	Pathway Commons Protein-Protein Interactions	1.0	null
OVK18	DepMap CRISPR Gene Dependency	1.0	2.41232
NUDT21	Pathway Commons Protein-Protein Interactions	1.0	null
PNPT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160373_1_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSE119978,GSE180930_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15091
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892179
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897281
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBFA	Pathway Commons Protein-Protein Interactions	1.0	null
lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SHP77	CCLE Cell Line Gene CNV Profiles	1.0	1.41935
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11566
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16319
peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185313
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFATC2IP	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00502
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826252
indicates	GeneRIF Biological Term Annotations	1.0	null
Choroid Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
EEF1D	Pathway Commons Protein-Protein Interactions	1.0	null
Flp-In-T-REx cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.228
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90592
SNU620	DepMap CRISPR Gene Dependency	1.0	2.40347
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5425-01A-02R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04524
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LTV1	Pathway Commons Protein-Protein Interactions	1.0	null
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.679
anion binding	GO Molecular Function Annotations 2015	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75013
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.54194
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2464
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64707
RPLP2	Pathway Commons Protein-Protein Interactions	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
LOX-1_OE_GDS4262_433_human_HAECT - aortic endothelial cell line - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
TMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32482
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTCA	Pathway Commons Protein-Protein Interactions	1.0	null
AGS	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.27491
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044484
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.14306
YY1	ENCODE Transcription Factor Targets	1.0	null
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	1.59026
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00012
ATP5D	Pathway Commons Protein-Protein Interactions	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53571
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SRSF11	Pathway Commons Protein-Protein Interactions	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
U2AF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92267
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29258
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216373
DDX6	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal oxidative phosphorylation	MPO Gene-Phenotype Associations	1.0	null
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27214
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44568
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FARS2	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC1A3	Pathway Commons Protein-Protein Interactions	1.0	null
GRWD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15915
RNMTL1	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69137
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14297
MCM5	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81552
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
DARS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.63909
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32105
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-GSEA_TET1-CCRF-CEM_SCR_vs_TET1_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLD1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825707
TFAM	Pathway Commons Protein-Protein Interactions	1.0	null
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.05816
NB1	DepMap CRISPR Gene Dependency	1.0	2.36846
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDHK1	Kinase Library Tyrosine Kinome Atlas	1.0	98.73
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51279
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-PC-A5DM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853769
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16172
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0717
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DACT1	Pathway Commons Protein-Protein Interactions	1.0	null
TIA1	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97959
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal embryonic tissue morphology	MPO Gene-Phenotype Associations	1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06363
NUSAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epicotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
NARS	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25774
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1004
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.26263
EEF1E1	Pathway Commons Protein-Protein Interactions	1.0	null
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298635
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356191
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84927
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974995
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.936
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF3C2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.876571
Choroidal Neovascularization	HuGE Navigator Gene-Phenotype Associations	1.0	null
MRPL47	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957924
HSQ89	DepMap CRISPR Gene Dependency	1.0	2.04671
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28846
RPP38	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBE2O	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08599
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310529
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02299
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.71001
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68406
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88374
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10875
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
MCF7_Busulfan_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131957
GSE112760,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AKAP1	Pathway Commons Protein-Protein Interactions	1.0	null
EIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
ESF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883694
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEP350	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2521
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044175
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831672
NOM1	Pathway Commons Protein-Protein Interactions	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02016
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
LS123	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21527
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGW	DepMap CRISPR Gene Dependency	1.0	2.17379
all	GWASdb SNP-Phenotype Associations	1.0	0.028851
HNRNPA3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE244072_2_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28615
SARS-BatSRBD_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66881
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gtpase activity	GO Molecular Function Annotations 2015	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379314
Respiratory chain complex IV	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
6709_PPY_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.525869
HIST1H1C	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1_KO_GSE40296_7_mouse_brain (telencephalon)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9077
decreased apoptosis	MPO Gene-Phenotype Associations	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TFB1M	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05467
SARS-CoV NSP16_Day4_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.38989
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60786
A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.19625
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53687
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11833
SNRPA1	Pathway Commons Protein-Protein Interactions	1.0	null
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904959
DDX50	Pathway Commons Protein-Protein Interactions	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38371
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.46602
UQCRC2	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02873
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK19_knockdown_162_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.4931
HCC1428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64355
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4004
EFO-27	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.83615
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863766
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33193
GTEX-R55D-1526-SM-48FEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85881
LSM3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59236
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33887
COGE352	DepMap CRISPR Gene Dependency	1.0	2.08736
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47797
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.855743
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRPF31	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15001
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MSH6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12262
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Photoreceptor outer segment membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
SRPRB	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19828
PMC4335056-pone.0116726.s005.xlsx-X-ChIP_NOT_TX100_QE-GENE_Official_symbol_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
Parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40595
C6orf203	Pathway Commons Protein-Protein Interactions	1.0	null
Root quiescent center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
4152_INTS7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.536266
OAT	Pathway Commons Protein-Protein Interactions	1.0	null
UQCRFS1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41372
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08093
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25061
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6921
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36614
MRPL11	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAZAP1	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS15	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
G3BP2	Pathway Commons Protein-Protein Interactions	1.0	null
poly(a) rna binding	GO Molecular Function Annotations 2015	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2679
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10867
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21175
ZRANB2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906748
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
ACOT9	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal trophoblast layer morphology	MGI Mouse Phenotype Associations 2023	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962235
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60751
Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8056754-JEM_20201169_TableS3.xlsx-Sheet1-Table_S3_iVENN_overlap_analysis_of_D20_IL-1_DOWN_GSE12467_MYC_DKO_GSE110018_PU-ER_TCELL_DOWN_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18483
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00376
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRSF2	Pathway Commons Protein-Protein Interactions	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UTP23	Pathway Commons Protein-Protein Interactions	1.0	null
1878_CRNKL1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.02405
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53168
Hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.043
BD-25-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232743
ABCF3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959092
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
guanyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06912
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H2AB	Pathway Commons Protein-Protein Interactions	1.0	null
CLTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00531
NDUFA13	Pathway Commons Protein-Protein Interactions	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-2.91323
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08985
CTCF	ENCODE Transcription Factor Targets	1.0	null
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57626
hsa-miR-655	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
Exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.436
A375SKINCJ1	DepMap CRISPR Gene Dependency	1.0	2.13291
daudi	HPA Cell Line Gene Expression Profiles	1.0	1.87789
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.923337
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97529
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.1082
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO Molecular Function Annotations 2015	1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209931
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1436
JAGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5412
BC-84-BQ58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254173
API5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994407
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876045
ZCCHC8	Pathway Commons Protein-Protein Interactions	1.0	null
U937	DepMap CRISPR Gene Dependency	1.0	2.147
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0055
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.6597
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26317
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35363
C2orf49	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19297
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR18	Pathway Commons Protein-Protein Interactions	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321737
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPL	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831445
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
A-CA-04-2009(H1N1)_18hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.76634
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU398	DepMap CRISPR Gene Dependency	1.0	2.36538
succinate-CoA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
PML	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380813
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.8282
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11644
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.946828
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989195
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40531
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plant cell papilla	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77724
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931242
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NSUN4	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71821
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7334
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84355
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bj	HPA Cell Line Gene Expression Profiles	-1.0	-0.866019
Plastid ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.944
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.773423
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6356
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHAF1A	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H0-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOP9	Pathway Commons Protein-Protein Interactions	1.0	null
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.447625
143B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_POU5F1_18700969	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01104
RPL23	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6183
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050858
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ALDH1B1	Pathway Commons Protein-Protein Interactions	1.0	null
RPS28	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6826
TP53	Pathway Commons Protein-Protein Interactions	1.0	null
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33801
MOLM14	DepMap CRISPR Gene Dependency	1.0	2.03332
French Canadian Leigh disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27983
GSE193993_0_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.54535
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60014
CCNT2	ENCODE Transcription Factor Targets	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5590-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ar_21330406_lncap_lof_human_gpl570_gds4113	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.293261
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CSTF1	Pathway Commons Protein-Protein Interactions	1.0	null
Type II site-specific deoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52259
Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218637
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.8504
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97969
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983639
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SRSF3	Pathway Commons Protein-Protein Interactions	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PF-59-CY33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424296
HslUV protease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
PMC11216188-peerj-12-17616-s013.pdf-81-NFXL1_NFXL1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal mitochondrial physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pollen tube tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.068
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11712
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ALDH18A1	Pathway Commons Protein-Protein Interactions	1.0	null
FMR1	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989931
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066085
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3451
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37461
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39543
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
ZNF787	Pathway Commons Protein-Protein Interactions	1.0	null
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158875
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
COLGALT1	Pathway Commons Protein-Protein Interactions	1.0	null
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07563
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929405
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.56835
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.029
plastid-encoded plastid RNA polymerase complex A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NAT10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHP134	DepMap CRISPR Gene Dependency	1.0	2.20436
Plastid nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.363
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ADD3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEx BloodVessel 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-13.9577
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
COBLL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81809
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.165
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZNF263	ENCODE Transcription Factor Targets	1.0	null
RARS2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
LARP4	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857353
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SDAD1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7153-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297053
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.44488
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.175
DAOY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91633
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43908
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824565
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	2.58904
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22825
DNAJC9	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.73557
MUT	Pathway Commons Protein-Protein Interactions	1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	2.22571
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.695
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TFPI	Pathway Commons Protein-Protein Interactions	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20472
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13269
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36692
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232807
ERH	Pathway Commons Protein-Protein Interactions	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOC3L	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220045
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49642
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17148
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2907_FAM216A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.503086
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7789
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32191
tonsil	HPA Tissue Gene Expression Profiles	1.0	0.886852
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31854
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47388
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33994
NXF1	Pathway Commons Protein-Protein Interactions	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490204
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01565
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22455
Protonema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34174
KD	DepMap CRISPR Gene Dependency	1.0	2.45109
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358456
5005_METTL4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.55409
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17176
XRN2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75864
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51168
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
DIS3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27084
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8011
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09002
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.53853
Muscular Dystrophy_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE3252	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.69757
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20081105-ST-1	GeneSigDB Published Gene Signatures	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057591
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
18535662-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11839
abnormal mitochondrion morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.275149
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribonucleoprotein complex biogenesis	GO Biological Process Annotations 2015	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
MAP4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211357_2_v_0_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
LSM6	Pathway Commons Protein-Protein Interactions	1.0	null
EXOSC5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRP9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72422
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0519
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12988
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68761
USF1	ENCODE Transcription Factor Targets	1.0	null
DCAF12L2	Pathway Commons Protein-Protein Interactions	1.0	null
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YJU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06234
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09167
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21904
TRIM25	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.821383
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980483
MYC	ChEA Transcription Factor Targets	1.0	null
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.264
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPT2	Pathway Commons Protein-Protein Interactions	1.0	null
WBSCR22	Pathway Commons Protein-Protein Interactions	1.0	null
EIF3A	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.778205
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898817
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056981
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17797
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66652
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23131
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834219
EXOSC4	Pathway Commons Protein-Protein Interactions	1.0	null
NFU1	Pathway Commons Protein-Protein Interactions	1.0	null
RING1	Pathway Commons Protein-Protein Interactions	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.451889
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54994
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cSARS Bat SRBD_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.55353
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8594_SUPT16H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.66436
ADD1	Pathway Commons Protein-Protein Interactions	1.0	null
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04259
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MARS	Pathway Commons Protein-Protein Interactions	1.0	null
BD-61-OO16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259611
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.862933
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84776
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZMYM4	Pathway Commons Protein-Protein Interactions	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
PUF60	Pathway Commons Protein-Protein Interactions	1.0	null
Embryogenic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066418
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057809
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal cell morphology	MPO Gene-Phenotype Associations	1.0	null
Automobile speeding propensity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34309
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24534
PABPN1	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF3A2	Pathway Commons Protein-Protein Interactions	1.0	null
FAM120A	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH661	CCLE Cell Line Gene CNV Profiles	1.0	1.568
SNRPE	Pathway Commons Protein-Protein Interactions	1.0	null
Proplastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.278
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZC3H15	Pathway Commons Protein-Protein Interactions	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOSL1_KO_GSE43695_681_mouse_lung, bleomycin treated	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833308
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61665
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0405
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22364
BUD31	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02251
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKAP8	Pathway Commons Protein-Protein Interactions	1.0	null
SCML2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-9.17126
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6FZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963844
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.5751
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09765
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04965
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.17213
biological regulation	GO Biological Process Annotations 2015	1.0	null
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal mitochondrial morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11748
Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFC2	Pathway Commons Protein-Protein Interactions	1.0	null
Magnetosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20612
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930423
TE9	DepMap CRISPR Gene Dependency	1.0	2.09588
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883966
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70251
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898297
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD3	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894036
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87994
Pollen tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
Caulonema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
MPHOSPH10	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62767
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85789
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19435
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.52556
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09127
MCF7_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134217
SLC25A12	Pathway Commons Protein-Protein Interactions	1.0	null
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190947_1_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intraparietal sulcus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58117
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
A172	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13655
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972968
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43349
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TARDBP	Pathway Commons Protein-Protein Interactions	1.0	null
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
SW1783	CCLE Cell Line Gene Expression Profiles	1.0	3.39375
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.67684
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS1	ChEA Transcription Factor Targets	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.99239
MRPL27	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40787
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHX8_Deficiency_GDS3254_600_mouse_Newborn ovaries	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28406
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.874595
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904157
True leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04713
DBT	Pathway Commons Protein-Protein Interactions	1.0	null
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01126
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41366
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5116
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047658
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39101
ABC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0903
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-CA-04-2009(H1N1)_12Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.60808
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bacterial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.494
5198_MRPL15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.552203
PRDX4	Pathway Commons Protein-Protein Interactions	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509708
NOC2L	Pathway Commons Protein-Protein Interactions	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPH	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.925831
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.994
Rh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.954
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53242
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438055
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27408
abnormal extraembryonic tissue morphology	MPO Gene-Phenotype Associations	1.0	null
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.492359
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRNP70	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS17	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275447
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15733
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suggests	GeneRIF Biological Term Annotations	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21662
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.925831
Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	2.26107
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.942571
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI1	CCLE Cell Line Gene Expression Profiles	1.0	1.63838
RL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.16148
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059888
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15995
MRRF	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrion organization	GO Biological Process Annotations 2023	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45769
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904157
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH684	CCLE Cell Line Gene Expression Profiles	1.0	1.38603
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
Diazinon	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRSF1	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A678-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A184-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETFA	Pathway Commons Protein-Protein Interactions	1.0	null
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.094
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281426
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39878
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55231
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904213
CPSF7	Pathway Commons Protein-Protein Interactions	1.0	null
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTF3C2	Pathway Commons Protein-Protein Interactions	1.0	null
RCC-FG2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.86156
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45007
NCIH322	DepMap CRISPR Gene Dependency	1.0	2.41821
C7orf50	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.715947
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC25A13	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876596
PARS2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF326	Pathway Commons Protein-Protein Interactions	1.0	null
Neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Leigh disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06617
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897636
fungal-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.203
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS18B	Pathway Commons Protein-Protein Interactions	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
embryo tissue necrosis	MPO Gene-Phenotype Associations	1.0	null
GBR 12909	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.14
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.245
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	3.12687
RBM19	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965046
DDX27	Pathway Commons Protein-Protein Interactions	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273159
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82544
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.839
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16644
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAD17	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
organelle part	GO Cellular Component Annotations 2015	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_60Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.54395
SMARCC1	Pathway Commons Protein-Protein Interactions	1.0	null
BCLAF1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043917
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02968
16527891-Table3	GeneSigDB Published Gene Signatures	1.0	null
Silver-Russell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Tamoxifen	CTD Gene-Chemical Interactions	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906175
In situ melanoma of skin_Epidermis_GSE4587	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52793
EHHADH	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cell death	GO Biological Process Annotations 2015	1.0	null
FIP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
ribosome assembly	GO Biological Process Annotations 2023	1.0	null
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49395
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94084
prenatal lethality	MPO Gene-Phenotype Associations	1.0	null
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31829
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.19742
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11748
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98304
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15546
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
LIN7C	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54195
Hydathode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.455
Stoma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.185
PUS7	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	2.07863
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01558
cisplatin_homo sapiens_gpl570_gse15372	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NDUFA9	Pathway Commons Protein-Protein Interactions	1.0	null
POLDIP2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-374c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975882
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.89918
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.472982
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4762-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.729
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39447
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01894
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.04427
GTP binding	GO Molecular Function Annotations 2023	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32943
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881056
AB-84-PK04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359491
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18938
IF-31-RN78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245398
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
C14orf166	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM26	Pathway Commons Protein-Protein Interactions	1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
MCF7_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00748378
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.971
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased cell death	MPO Gene-Phenotype Associations	1.0	null
OCIAML2	CCLE Cell Line Gene Expression Profiles	1.0	1.86098
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KIAA0391	Pathway Commons Protein-Protein Interactions	1.0	null
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.191
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C2	ENCODE Transcription Factor Targets	1.0	null
A-CA-04-2009(H1N1)_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.21295
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.09
RPL38	Pathway Commons Protein-Protein Interactions	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29096
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85208
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.397
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68435
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
MET_knockout_260_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.15738
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931284
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13735
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09251
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11996
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22302
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.330589
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3974
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hmgn1_KO_GDS5010_405_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MRPS9	Pathway Commons Protein-Protein Interactions	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893253
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16727
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046149
embryonic lethality during organogenesis	MPO Gene-Phenotype Associations	1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX42	Pathway Commons Protein-Protein Interactions	1.0	null
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGFBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.91
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07355
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405125
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00452
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365004
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycolate oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.216
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1316
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87439
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884142
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862044
EPB41L1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01562
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
D458	DepMap CRISPR Gene Dependency	1.0	2.16672
Siphon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28954
PMC5896143__F1	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRMT6	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH1L2	Pathway Commons Protein-Protein Interactions	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052941
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35036
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
hela	HPA Cell Line Gene Expression Profiles	-1.0	-0.990191
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23668
Plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.029
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00774
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.158
DAP3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83814
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74162
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC332 (ARAF)	NURSA Protein Complexes	1.0	null
AKT1_knockout_210_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.58461
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3853
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-dORF6_84Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.29047
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9371
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLRG1	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
PPP1R3A	Pathway Commons Protein-Protein Interactions	1.0	null
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.912
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57035
Trophoblast giant cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49731
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89189
MTHFD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.15156
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10104
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.85342
estradiol_homo sapiens_gpl1225_gse1486	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rabies CVS-11_7day-Spinalcord_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57548
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0926-SM-48TZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954367
NUMA1	Pathway Commons Protein-Protein Interactions	1.0	null
SYNE1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LSM7	Pathway Commons Protein-Protein Interactions	1.0	null
DLD	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976469
TM31	CCLE Cell Line Gene CNV Profiles	1.0	2.31191
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29011
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293156
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.51037
POLD3	Pathway Commons Protein-Protein Interactions	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998232
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.58779
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58935
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43955
Circularly permuted (CP)-type guanine nucleotide-binding (G) domain	InterPro Predicted Protein Domain Annotations	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2381
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inducing	GeneRIF Biological Term Annotations	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053936
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.62
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161635
CP66-MEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.06344
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23209
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546306
VDR	ChEA Transcription Factor Targets	1.0	null
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961004
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SLC25A4	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrial inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10578
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-1.20555
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.3587
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
SUB1	Pathway Commons Protein-Protein Interactions	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.970036
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90147
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03598
GTEX-TMMY-0726-SM-33HBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08556
RGAG1	Pathway Commons Protein-Protein Interactions	1.0	null
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
HBEGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39421
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95741
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIST1H4F	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924382
SKUT1	DepMap CRISPR Gene Dependency	1.0	2.29196
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLAD1	Pathway Commons Protein-Protein Interactions	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYCR2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
embryonic growth retardation	MPO Gene-Phenotype Associations	1.0	null
AHDC1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL15	Pathway Commons Protein-Protein Interactions	1.0	null
MICU1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32491
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_ID_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRSF7	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CECR5	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2333
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
MATR3	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13384
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARCKSL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
spleen	HPA Tissue Protein Expression Profiles	-1.0	-2.18484
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1368
MRPL24	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24688
KU-19-19	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.4635
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86765
Idiosyncratic drug effect_Hepatic Tissue_GSE2825	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.71906
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	2.33964
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
RBMX	Pathway Commons Protein-Protein Interactions	1.0	null
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41571
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MALSU1	Pathway Commons Protein-Protein Interactions	1.0	null
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01073
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3C	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DTYMK	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TSR1	Pathway Commons Protein-Protein Interactions	1.0	null
METTL17	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-15-VA57_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415556
POU5F1-18700969-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial ribosome	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-292-Clone-A141B1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.34443
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.492544
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.364
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA0020	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7158-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SYMPK	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS25	Pathway Commons Protein-Protein Interactions	1.0	null
TEFM	Pathway Commons Protein-Protein Interactions	1.0	null
Posterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5116-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYCRL	Pathway Commons Protein-Protein Interactions	1.0	null
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydrolase activity, acting on acid anhydrides	GO Molecular Function Annotations 2015	1.0	null
SRSF4	Pathway Commons Protein-Protein Interactions	1.0	null
RPL8	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
MET_knockout_248_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.92743
SLC27A2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.201672
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066116
TMLHE	Pathway Commons Protein-Protein Interactions	1.0	null
organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.879173
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
SPATS2L	Pathway Commons Protein-Protein Interactions	1.0	null
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.683
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829238
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.45053
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPT1A	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS27	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97313
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STS-0421	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.89519
IGF2BP1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0404
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07508
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5896
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31389
NGRN	Pathway Commons Protein-Protein Interactions	1.0	null
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
extrinsic component of mitochondrial inner membrane	GO Cellular Component Annotations 2023	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08912
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951629
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
11143_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.677309
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058135
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40111
NARS2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5327-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39223
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953354
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3859
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05798
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.381
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71028
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8984
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32876
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.181
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54508
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
RBM15	Pathway Commons Protein-Protein Interactions	1.0	null
EW8	DepMap CRISPR Gene Dependency	1.0	2.05846
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0716
HP1BP3	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FUBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18249
RPL24	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
RPS26	Pathway Commons Protein-Protein Interactions	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.868
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5332-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13187
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMGB1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10830421-41589_2023_1452_MOESM5_ESM.xlsx-HEK293T_MAX-Tg_tissues-Unnamed_0_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960652
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
icSARS CoV_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58053
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83086
RPS12	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1680-01A-02R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LARP1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PPIG	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMPCB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988488
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1687
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLP-8	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59281
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050752
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.035
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDF	Pathway Commons Protein-Protein Interactions	1.0	null
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6565
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984434
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A953-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP39	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.12204
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13181
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3M	Pathway Commons Protein-Protein Interactions	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.952788
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44834
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09322
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202254
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18537
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y0-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prenatal growth retardation	MPO Gene-Phenotype Associations	1.0	null
MPG	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852558
YIPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02316
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74631
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3444-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KCTD12	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09102
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
Ectoplacental cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55464
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60651
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01021
PRRC2A	Pathway Commons Protein-Protein Interactions	1.0	null
SW579	CCLE Cell Line Gene CNV Profiles	1.0	1.81043
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11187
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.925
CBC2152 (RFWD3)	NURSA Protein Complexes	1.0	null
organelle organization	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12362
RPLP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-8035-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
brl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.884199
NFIC	ENCODE Transcription Factor Targets	1.0	null
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MV411	DepMap CRISPR Gene Dependency	1.0	2.34506
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00747
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.15623
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7576-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2029
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATAD3B	Pathway Commons Protein-Protein Interactions	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01015
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06456
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97249
PMC12866144-mmc3.xlsx-Sheet1-Table_S2_List_of_genes_that_comprehend_the_TP53_AML_signature_generated_in_this_manuscript_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SUDHL10	CCLE Cell Line Gene Expression Profiles	1.0	1.39552
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.146
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null