association	dataset	threshold value	standardized value
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.561
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
BRD-K26272845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43106
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.930193
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88119
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.788
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837415
decreased total body fat amount	MPO Gene-Phenotype Associations	1.0	null
GSE226452_1_v_2_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCIH522	DepMap CRISPR Gene Dependency	1.0	3.67656
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6178
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.64857
Artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
Meniere's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.14102
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57826
BRD-K12555854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44466
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5738
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Tunica media vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
SCAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18779
oxytetracycline-3170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RHO GTPase cycle	Reactome Pathways 2024	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90928
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066951
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27544
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7381
BRD-K48999921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54199
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89512
BRD-K00620786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27359
Aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
Hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69331
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48838
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857819
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47902
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30732
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.881
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20562
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27057
modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20111
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1491
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
PGM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88487
PROPYLTHIOURACIL	DGIdb Drug Targets 2026	1.0	1.7644
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
pulmonary emphysema	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.71078
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05345
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18577
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.974724
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884707
mitogenactivated	GeneRIF Biological Term Annotations	1.0	null
MPP-89	COSMIC Cell Line Gene Mutation Profiles	1.0	null
oxidases	GeneRIF Biological Term Annotations	1.0	null
BRD-K31908823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16624
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06668
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36885
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
several	GeneRIF Biological Term Annotations	1.0	null
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
BRD-K60019754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76921
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2921
LIVF001-005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11109
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09937
Midbrain reticular nucleus, retrorubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04347
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02837
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42488
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34581
palmitateinduced	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04452
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05902
C32	CCLE Cell Line Gene Expression Profiles	1.0	1.59588
NADPH oxidase complex	GO Cellular Component Annotations 2025	1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.64026
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41127
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	0.681983
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4444
lipoprotein(a)	GAD Gene-Disease Associations	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27727
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929167
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5614
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44553
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63592
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70684
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11554977-40199_2024_523_MOESM2_ESM.xlsx-Sheet1-Supplement_2_Metformin_Drug_Sensitivity_and_Damaging_Mutation_by_using_PRISM_Repurposing_Primary_Screen_and_Damaging_Mutation_in_DepMap_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07861364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05949
BRD-K28107038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19372
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.592232
MC116	CCLE Cell Line Gene Expression Profiles	1.0	1.36334
Alveolar epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
NCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93274
BRD-K58644442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40417
BRD-K19011391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1158
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rac1	GeneRIF Biological Term Annotations	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060876
circling	MGI Mouse Phenotype Associations 2023	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0723
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K27656392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30671
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78383
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049814
Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.04835
SUDHL8	CCLE Cell Line Gene CNV Profiles	1.0	2.00503
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09568
BRD-K72707702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70954
Hip	dbGAP Gene-Trait Associations	1.0	0.412313
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
metabolic process	GO Biological Process Annotations 2015	1.0	null
oxidoreductase complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.003377
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95909
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
BRD-K35760166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18439
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28329571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62307
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49639
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	2.72668
BRD-K82249895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81057
A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71969
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6628
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2539
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5164
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59333
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28009
BRD-K01894374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56122
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071042
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864584
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4904
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6654
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1021
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97792
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064306
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8932
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4901
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09836
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.973882
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19266
signal	GeneRIF Biological Term Annotations	1.0	null
BRD-K70756309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45684
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94261
response to stimulus	GO Biological Process Annotations 2015	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44456
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078162
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03872
Nuclear envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
PMC9378837-Table_3.xlsx-ESR2_upstream_regulators-2000-2021_QIAGEN_All_rights_reserved_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47098496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67518
Polymorphonuclear leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91293
Asthma	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K61599229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25688
HDMYZ	CCLE Cell Line Gene Expression Profiles	1.0	1.5297
Mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.103
thioredoxin-disulfide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.599
Glutathione synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
detection of gravity	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23964
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69635
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.867
fenbendazole-3805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6308
EGR3_01_34	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.5518
butyl hydroxybenzoate-5245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FAM236B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47945
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43693
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
BLCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8817
Epithelial lining fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41625
RHO GTPase Effectors	Reactome Pathways 2024	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9559
Signal Transduction	Reactome Pathways 2024	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9997
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1254	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Autosomal recessive nonsyndromic deafness 104	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867094
Peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.784
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5123
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57919
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39169
SARS-CoV MA15_Day7_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.44684
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17371
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.878971
NCIH1734	CCLE Cell Line Gene CNV Profiles	1.0	1.3834
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.83788
PMC11950762-BLOODA_ADV-2024-014354-mmc2.pdf-53-HEY1_HEY1	Rummagene Transcription Factor Associations 2026	1.0	null
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
BRD-K36353158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09772
BRD-K26636241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06834
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K90052868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0087
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5938
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58288
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9113
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4119
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54264
oxidoreductase activity, acting on nad(p)h, oxygen as acceptor	GO Molecular Function Annotations 2015	1.0	null
leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.124666
MAML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20531
Resting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97149
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21497
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Lung adenocarcinoma_LUAD_TCGA-86-A4P7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45281
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.93396
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08818
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16495
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
BRD-K21990111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32671
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
Neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.94
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHOS2	CCLE Cell Line Gene Expression Profiles	1.0	1.63195
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58288
BRD-K50603336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38275
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5032
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03489
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K87511374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17032
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55727
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13123
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3131
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827759
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.66926
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6587
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05251
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12851
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80356
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60951
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.604
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0293
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08745
PMC8650509__F4	PFOCR Pathway Figure Associations 2024	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01381
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68426
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78654
Aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11099
decrease	GeneRIF Biological Term Annotations	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25541
pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371994
saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.941785
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57754
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347778
BRD-K56470219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65002
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411631
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	0.975375
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8087
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.16174
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04153
BRD-K28991565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41244
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8948
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135584
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30541
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
Capsaicin	CTD Gene-Chemical Interactions	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.6604
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20863
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8505
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122657
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.4021
renal	GeneRIF Biological Term Annotations	1.0	null
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38817
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.24167
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.16833
hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.385936
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3395
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11334
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K65445351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.743
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90019187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36247
BRD-K13069055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54459
SMARCA4	ChEA Transcription Factor Targets	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1453
HS939T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32917
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886129
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4444
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38235
Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97489
Mitochondrial respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-2.40137
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080347
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58236
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12139
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840237
RI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57273
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22822
NCIH2066	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45709
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.49867
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84631
Infertility, Male	CTD Gene-Disease Associations	1.0	1.02003
TCCSUP	CCLE Cell Line Gene Expression Profiles	1.0	1.38321
altered righting response	MPO Gene-Phenotype Associations	1.0	null
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62707
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Brain Lower Grade Glioma_LGG_TCGA-DU-7301-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	3.23819
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17509
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.6008
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
p67phox	GeneRIF Biological Term Annotations	1.0	null
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31323
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96463
BRD-K35128023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1308
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33031
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7714
abnormal food intake	MGI Mouse Phenotype Associations 2023	1.0	null
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.51106
Respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.817
Cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.689
BRD-K21284411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04184
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9891
NRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07055
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31761
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2818
PMC7896717__F3	PFOCR Pathway Figure Associations 2023	1.0	null
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.878
MYC	ChEA Transcription Factor Targets	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08886
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
plb-985 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614974
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24793
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94914
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.00062
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1086
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.25735
Carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28423
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.248578
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06316
decidual cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227186
BRD-K38481376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17143
myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081921
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10324
disease	GWASdb SNP-Disease Associations	1.0	0.034232
oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.111869
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.22649
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92125
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17246
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94499
cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159445
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36402
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06732
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355198
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.75515
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21427
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
Renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.556
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31356
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.57985
BRD-K87815532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24743
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.33406
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09419
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.88218
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.073
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
Inflammation	CTD Gene-Disease Associations	1.0	1.22566
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061274
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
NFKBIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93687
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31572
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01025
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.094
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38981
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96584
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.931908
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17233
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
Lung microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.255
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46394
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28019
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.32121
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827759
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.4004
Cerebrovascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66717
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
OVCA420	DepMap CRISPR Gene Dependency	1.0	6.20645
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27551
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.885
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21151
cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.207578
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41161
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57963
SW626	DepMap CRISPR Gene Dependency	1.0	3.74081
ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.312224
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01611
Lipoprotein (a) levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.598117
BRD-K23430114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81085
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
LB2241-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51879
Promyelocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.838
abnormal locomotor coordination	MPO Gene-Phenotype Associations	1.0	null
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37971
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6758
decreased total body fat amount	MGI Mouse Phenotype Associations 2023	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21411
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.65613
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13172
OVISE	DepMap CRISPR Gene Dependency	1.0	3.50581
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46142
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
CRCGN014_HEPG2_3H:C06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38288
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07818
CLASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58445
Ferric reductase, NAD binding	InterPro Predicted Protein Domain Annotations	1.0	null
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4217
LDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70549
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48916
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169168
hsa-miR-920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.25588
Dimensional psychopathology (Arousal)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
BRD-K34335352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62817
Pedunculopontine nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06121
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91309
stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166643
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.32385
NSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29657
enzyme	GeneRIF Biological Term Annotations	1.0	null
nitric-oxide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07997
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.975782
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0196
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99914
nox3	GeneRIF Biological Term Annotations	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.81624
abnormal vestibuloocular reflex	MPO Gene-Phenotype Associations	1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	2.03536
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69522
Lung endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
hiv	GAD Gene-Disease Associations	1.0	null
Endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.901
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.291
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29346
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Interalveolar septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
natamycin-3548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49125116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10435
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77228
EB1	CCLE Cell Line Gene Expression Profiles	1.0	1.74658
abnormal body temperature homeostasis	MPO Gene-Phenotype Associations	1.0	null
GSE111247_14_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32396
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228234
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
Lung epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
Chlorine	HMDB Metabolites of Enzymes	1.0	null
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80623
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066333
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
assembly	GeneRIF Biological Term Annotations	1.0	null
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07672
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4084
intermediate stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13874
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50665
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.180688
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20194
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.12668
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2661
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01925
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15216
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5557
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22435
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6312
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2963
Labyrinthitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66098
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81415
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88152
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.099
nox1	GeneRIF Biological Term Annotations	1.0	null
alcohol abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.27687
hsa-miR-4803	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.868
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14819
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39561
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42689
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.627
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25794
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10209
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56498
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78428
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p22phox	GeneRIF Biological Term Annotations	1.0	null
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4412
impaired balance	MPO Gene-Phenotype Associations	1.0	null
TC71	CCLE Cell Line Gene CNV Profiles	1.0	1.57411
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44906
microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.586427
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.125
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75855
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
pantothenic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12189
stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390799
vascular disease	GWASdb SNP-Disease Associations	1.0	0.124798
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.07255
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22585
DOV13	CCLE Cell Line Gene CNV Profiles	1.0	1.49984
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2574
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27979
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099581
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01665
Lung endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.475
PMC8502826__F10	PFOCR Pathway Figure Associations 2024	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.66722
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15095
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7629
PMC8431385__F3	PFOCR Pathway Figure Associations 2024	1.0	null
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060381
Cerebral amyloid angiopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.98696
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03018
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22957
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34811
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.49773
BRD-K36021765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18806
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54051
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2032
HPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14666
Pork consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.909691
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46944
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903401
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4487
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nadph oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.90355
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.652
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K65416438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29158
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02862
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8011
BRD-K05246869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79716
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.223
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23011
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.861
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19704
BRD-K70979181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05537
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02302
LS-513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06234
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6616
PGLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55631
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17322
transmission	GeneRIF Biological Term Annotations	1.0	null
nox	GeneRIF Biological Term Annotations	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1791
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02045
OAW42	DepMap CRISPR Gene Dependency	1.0	4.23052
A-VN-1203-2004(H5N1)_Day7-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.73451
utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30748
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.74594
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
UACC-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44931
GLC-82 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
Ventral surface of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
single-organism process	GO Biological Process Annotations 2015	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41159
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.362
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
Podosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23028
BRD-K76764002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28861
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7184
BRD-K63628486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24012
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02902
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17195
LRRC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48791
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118365
Smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.135
carbenoxolone-4093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31157
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57832
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
using	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3416-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32120119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02936
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188602
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9571
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2312
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
nadph	GeneRIF Biological Term Annotations	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31821
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01387
abnormal membranous labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
MMDD1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.507
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15519
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09457
Intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965424
catalytic complex	GO Cellular Component Annotations 2015	1.0	null
BRD-K24743998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49293
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.034
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82039
Cardiofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4079
oxaprozin-3876	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72231
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12737
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3116	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18569
PMC5463201__F2	PFOCR Pathway Figure Associations 2023	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.44869
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
temperature homeostasis	GO Biological Process Annotations 2015	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827759
Perturb_13852_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HCC2998	DepMap CRISPR Gene Dependency	1.0	5.49243
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.827493
USP34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90361
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26963
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42689
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04234
organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.097
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24713
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11943
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.36899
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	0.883961
RAC3 GTPase cycle	Reactome Pathways 2024	1.0	null
hsa-miR-494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6691
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GEMIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09384
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66358
IKBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0337
NR3C1	ChEA Transcription Factor Targets	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11596949-medi-103-e40529-s003.xlsx-TCMSP_1-PGR_PGR	Rummagene Transcription Factor Associations 2026	1.0	null
deferoxamine_homo sapiens_gpl13497_gse30774	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31772
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.23645
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
NADPH oxidase 3	InterPro Predicted Protein Domain Annotations	1.0	null
ARID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95891
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.021
Mitochondrial respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.192
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13786
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10324
pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55371
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46542
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44515
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.09892
sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.359289
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8986
PMC9846571-Table_1.xls-1-NFE2L2_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.403
C1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1182
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.179802
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.56
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79716
BRD-K96063588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12014
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.768701
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.295739
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.924623
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09785
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30601
PMC6831867__F1	PFOCR Pathway Figure Associations 2024	1.0	null
intermediate stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32832
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61758
BRD-K66207462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27806
BRD-K43435656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5509
Fever	DisGeNET Gene-Phenotype Associations	1.0	null
MALME-3M cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53761
BRD-K50961262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1845
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
Colonic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.479
ARMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18335
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35762
corynanthine-4227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53585
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
BRD-K69692345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10075
BRD-K23499378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77647
jerky movement	MPO Gene-Phenotype Associations	1.0	null
allergic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.209248
BRD-K55864253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30983
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.73408
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65055
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5571
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2791
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59934
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.55605
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.05915
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
BRD-K24070365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78738
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054322
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9425
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NUP214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49548
Congenital hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52999
coronary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452584
BRD-K51275565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67944
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57352
human lung microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.994119
hepatic	GeneRIF Biological Term Annotations	1.0	null
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33669
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088662
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.979754
Respiratory chain complex IV	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
HUPT4	DepMap CRISPR Gene Dependency	1.0	3.38037
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72629
resistance	GeneRIF Biological Term Annotations	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4238
BRD-K61451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02937
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5405
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3311
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8732
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.396
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
PMC11314475__F5	PFOCR Pathway Figure Associations 2024	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1898
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5836-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055487
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82835
r1 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13631
SK-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95514
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16578
CRCGN014_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69448
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435289
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
BRD-K90154335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.4015
BRD-K37527074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91783
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52553
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.112
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33246
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL8346 (KIAA1688)	NURSA Protein Complexes	1.0	null
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3688
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5976
Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5186-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27346
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.905831
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.00161
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68B-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5628
EP300	ChEA Transcription Factor Targets	1.0	null
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25145
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63715
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50633
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p47phox	GeneRIF Biological Term Annotations	1.0	null
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	2.97954
Benign paroxysmal positional vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
BRD-K69350885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30891
abnormal postural reflex	MPO Gene-Phenotype Associations	1.0	null
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75931
BRD-K21771537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57101
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7915
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K47804666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28717
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84461
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1372
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82766
Mitochondrial permeability transition pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2323
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
Space motion sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01773
BRD-K06896230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42901
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26505
intermediate stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18901
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
SK-LMS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54131
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS81	DepMap CRISPR Gene Dependency	1.0	2.73861
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
BRD-K90665148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52234
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.125401
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67743
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7429
NCIH1993	DepMap CRISPR Gene Dependency	1.0	7.39002
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80585
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	5.04711
BRD-K37634338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10224
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4772
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98994
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7978
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.388
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NADPH oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.308
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
BRD-K68300789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06394
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05412
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediated	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01745
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.24395
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88376
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64743
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74252
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58334
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22279
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01197
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56868
NO10	DepMap CRISPR Gene Dependency	1.0	2.06718
Intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.817
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.301
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63828
Alveolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
BRD-K04704273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53515
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92884
Diabetes Mellitus, Type 1	CTD Gene-Disease Associations	1.0	1.1437
Essential hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55684
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Plasma membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.889
BRD-K03765511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83181
Autosomal recessive nonsyndromic deafness 67	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	1.36917
abnormal gait	MGI Mouse Phenotype Associations 2023	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079502
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2438
CRCGN014_HEPG2_3H:N24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09227
Superoxides	CTD Gene-Chemical Interactions	1.0	null
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13475
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
abnormal circadian rhythm	MPO Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59819
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41475
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4237
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.096781
diabetic	GeneRIF Biological Term Annotations	1.0	null
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55205
NB13	DepMap CRISPR Gene Dependency	1.0	7.33697
Chronic granulomatous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.995
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87822
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57519
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.833
Hypopharyngeal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11258
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Phagocyte bactericidal dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
RHO GTPases Activate NADPH Oxidases	Reactome Pathways 2024	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.143
PMC9378837-Table_3.xlsx-Venn_Diagram_Upstream_regulat-574_elements_included_exclusively_in_ESR2_Upstream_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36689392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51618
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37098
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24212
NDUFA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26757
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03837
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178011
BRD-K87541124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21171
BRD-K77795481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03489
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.669
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.34439
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6602
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2391
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35757
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45867
PMC4516600__F4	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56865
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30601
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67894
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92543
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25218
Cystic Fibrosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.016
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Fertilization envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
abnormal inner ear morphology	MPO Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.822
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37184
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06563
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05894
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57026
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40668
BRD-K39863565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01876
sirna	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9587
Multiple Sclerosis, Relapsing-Remitting	DisGeNET Gene-Disease Associations	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09922
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37368
Lung epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.953435
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE510	CCLE Cell Line Gene Expression Profiles	1.0	1.51498
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39138
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.624
BRD-K96575636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11208
BRD-K30724479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71045
Pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.49
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44781
Pulmonary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
H4C9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23481
Brain Lower Grade Glioma_LGG_TCGA-DU-7008-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
otolith development	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6893
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43013
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
abnormal body fat mass	MPO Gene-Phenotype Associations	1.0	null
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16242
BRD-K04272258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40598
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.994925
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
CLTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5868
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10535
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85764
Respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.16
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34404
OCILY19	CCLE Cell Line Gene CNV Profiles	1.0	1.52169
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041638
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.627
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81179
BRD-K94196749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53149
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93477
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39396
16434974-Table2	GeneSigDB Published Gene Signatures	1.0	null
nadph oxidase complex	GO Cellular Component Annotations 2015	1.0	null
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45193
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69601
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42918
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45981
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
BRD-K05051664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90279
generation	GeneRIF Biological Term Annotations	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.41955
BRD-K76150628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91485
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18336
inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.188938
Lung Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.95845
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4214
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
BMI-1_DEPLETION_GDS2445_115_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203275
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30083
PMC11596949-medi-103-e40529-s002.xlsx-final_targets-PGR_PGR	Rummagene Transcription Factor Associations 2026	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
External carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
HUH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07054
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32219
Cytochrome b245, heavy chain	InterPro Predicted Protein Domain Annotations	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8544
immune	GAD High Level Gene-Disease Associations	1.0	0.295739
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0111
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45343
Femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NH-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83935370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05908
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65731
abnormal vestibular labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
multicellular organismal homeostasis	GO Biological Process Annotations 2015	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.250663
metabolic	GAD High Level Gene-Disease Associations	1.0	0.326393
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43218
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45931
BRD-K87167435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25299
Cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
CDKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33698
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73652
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93395
Colitis, Ulcerative	HuGE Navigator Gene-Phenotype Associations	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6684
SEPTIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19206
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0555
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04248
BRD-K83603369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50179
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64333
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.03626
SW962	GDSC Cell Line Gene Expression Profiles	1.0	1.81827
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214576
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91006
r3 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76946
Oxidative stress response	WikiPathways Pathways 2024	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10540354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1055
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
Colonic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.737
oxidoreductase activity, acting on nad(p)h	GO Molecular Function Annotations 2015	1.0	null
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14155
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
PARK7_KD_GDS3750_2_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perilymphatic space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3192
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37482
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17187
BRD-K91022335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18159
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28262
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10757
BRD-K06203932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29463
hsa-miR-375	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32346
activators	GeneRIF Biological Term Annotations	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.563
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
CCK81	DepMap CRISPR Gene Dependency	1.0	4.2418
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03105
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47572
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17786
Ferric reductase transmembrane component-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827759
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22065
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4051
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6569
BRD-K71944937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53661
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2934
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3176
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7508
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0093
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
KURAMOCHI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21161
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
response to gravity	GO Biological Process Annotations 2015	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
Vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.816
vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.568424
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0439
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47375
BRD-K69854611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08696
Superoxide dismutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90878
Adult respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.324
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70929
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27864
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26526202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31259
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26898
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45717
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
FAD-binding 8	InterPro Predicted Protein Domain Annotations	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.30906
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99194
BRD-K63487554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46968
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0991
catalytic complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001651
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pouchitis	HuGE Navigator Gene-Phenotype Associations	1.0	null
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71428
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18695
insulininduced	GeneRIF Biological Term Annotations	1.0	null
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05391
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55543
r1 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1964
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
poor grooming	MGI Mouse Phenotype Associations 2023	1.0	null
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81793
DJ-1_KD_GDS3750_373_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.57791
BRD-K22944782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09665
BRD-K77519898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27636
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37547
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88849
functionally	GeneRIF Biological Term Annotations	1.0	null
resting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7105
Perturb_16092_KD_RRM2_SRP398748	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.04742
NCIH1581	CCLE Cell Line Gene Expression Profiles	1.0	2.41182
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8345
PMC7186402__F1	PFOCR Pathway Figure Associations 2024	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04495
ANP32D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08153
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34936
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
BRD-K10017294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03325
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1086
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37613
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5155-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85458
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
ADCY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69347
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9174
BRD-K19766710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19907
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K47165178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08179
Pollen tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1686
intermediate part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24584
Vallate papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079789
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10037
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14191
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8307
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43986
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58288
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
abnormal otolith morphology	MPO Gene-Phenotype Associations	1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14312
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.63667
Arterial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26234
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.147685
Coronary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
Riboflavin synthase-like beta-barrel	InterPro Predicted Protein Domain Annotations	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.50197
SNU61	CCLE Cell Line Gene CNV Profiles	1.0	1.40556
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66677
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15937
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345558
BT16	DepMap CRISPR Gene Dependency	1.0	2.98939
BRD-K12633506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01305
vesicle	GO Cellular Component Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.368
abnormal vestibular system physiology	MPO Gene-Phenotype Associations	1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
HEI-OC1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.388
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064672
icSARA deltaORF6_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71003
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25905
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5719
Cardiac microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195856
cellular_component	GO Cellular Component Annotations 2015	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67628
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1595
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278955
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.624
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3004
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1305
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29633
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14353
intermediate part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42138
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25825
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94675
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49979
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250953
CYP27C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77375
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5267
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218186
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
Microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.786
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.8892
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66803
glycerol-3-phosphate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367129
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19027
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3959
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30154
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198386
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30749
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48078
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943701
BRD-K22449045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26036
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39942
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.8
HLMVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40896
chromium hexavalent ion	CTD Gene-Chemical Interactions	1.0	null
BRD-K52154207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59368
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62915
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.459274
Traumatic brain injury	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10193
CRCGN008_HEPG2_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05305
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.27045
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.37771
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03575
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86198
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.131
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91867
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5906
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.308587
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44134
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80917
septopallidal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80005
arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.207912
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3993
BRD-K06116445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22303
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55389
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25874
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4768
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.679324
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.8678
BRD-K10704442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24056
BRD-K18298066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36238
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.854185
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942397
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.64505
Brain Lower Grade Glioma_LGG_TCGA-F6-A8O4-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	2.01216
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34165
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0676
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carotid sinus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
BRD-K23292451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13062
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
BRD-K75900952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57668
BRD-K82670191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01363
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21229
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854745
MYCN_01_296	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.46619
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	1.88218
icSARA deltaORF6_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65531
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96838
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02965
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44262
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26183
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17272
EIF5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90811
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.8518
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27164
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058616
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91657
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.755
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U4-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
Vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.184
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2799
production	GeneRIF Biological Term Annotations	1.0	null
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51731
regions	GeneRIF Biological Term Annotations	1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59575
19377508-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01238
PMC7978298__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8627
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00463
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406694
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97448504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36571
distinct	GeneRIF Biological Term Annotations	1.0	null
Dimensional psychopathology (Negative)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20111
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39743
p38mapk	GeneRIF Biological Term Annotations	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32219
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32972
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81204
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64167
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3387
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.03862
BRD-A98099470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07389
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17084
BRD-K88881681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31153
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45569
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.091
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29388
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41202
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040385
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42191
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28099
noxo1	GeneRIF Biological Term Annotations	1.0	null
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75963
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7365
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05199
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64377
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
Cochlear labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
NCIH1395	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15396
BRD-K74162965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21974
BRD-K95114614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24507
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01009
artery disease	GWASdb SNP-Disease Associations	1.0	0.169479
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29511
OLIG2	ChEA Transcription Factor Targets	1.0	null
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.100984
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4278
Infertility, Female	CTD Gene-Disease Associations	1.0	1.1403
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06732
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065885
CRCGN013_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04027
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.69803
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.112
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92997
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60988
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22145
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4221
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08677
BRD-A70099008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09469
NCI-H322 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45257
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.27073
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60469
MDA-MB-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2525
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5684-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54051
abnormal circadian temperature homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
brain	GTEx Tissue Gene Expression Profiles	1.0	0.936188
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36967
BRD-K87449690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1135
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31761
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
SW1710	GDSC Cell Line Gene Expression Profiles	-1.0	-2.07667
hip	GAD Gene-Disease Associations	1.0	null
BRD-K95435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32095
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.28025
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76239
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27135
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9277
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0924
BRD-K13225050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06732
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74936
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062139
BRD-K89660028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2643
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040708
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245491
abnormal gait	MPO Gene-Phenotype Associations	1.0	null
superoxide anion generation	GO Biological Process Annotations 2015	1.0	null
middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221755
substantia nigra compacta, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25121
Hypertension	CTD Gene-Disease Associations	1.0	1.26978
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92057
BRD-K51522005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04863
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Barrett's esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09469
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.44999
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43427
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.429443
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15539
A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.16571
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8654
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878716
pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192874
SLC25A22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7434
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50018
BRD-K80442083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08159
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16042
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Internal carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2378
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56775
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49856
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84277
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
BRD-K08205503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09433
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066807
abnormal righting response	MGI Mouse Phenotype Associations 2023	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
BRD-K00183357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45033
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.74594
myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323874
intermediate part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16553
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08504
KK-47 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52041
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15378
SPI1	ENCODE Transcription Factor Targets	1.0	null
CCD-19LU cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70388
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10121
NCI-H929	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16408
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00347
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3105
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.42071
invasion	GeneRIF Biological Term Annotations	1.0	null
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89264
Coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
RNF149	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5899
SGTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49812
59M	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69921
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50447
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29521
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87224
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00815
NR2F2	ENCODE Transcription Factor Targets	1.0	null
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89355
Winchester syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.17579
Pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abdominal aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
abnormal ear morphology	MPO Gene-Phenotype Associations	1.0	null
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
pentetic acid-5629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5345
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23608
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24782
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19648
Pollen tube tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57416
Nascent polypeptide-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.797
PMC6831867__F1	PFOCR Pathway Figure Associations 2023	1.0	null
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05329
Arterial endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
p4244	GeneRIF Biological Term Annotations	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Hyperinsulinism	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.05622
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.58589
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Spiral organ cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51975
Preosteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36957
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90987
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7969
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17418
BRD-K83645749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36757
conclusion	GeneRIF Biological Term Annotations	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5813
BRD-K90527476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12649
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13789
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.202346
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.761
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.34267
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3211
BRD-K56976888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45556
Edema	CTD Gene-Disease Associations	1.0	1.27905
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37216
BRD-K56004278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43952
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32746
PL4	DepMap CRISPR Gene Dependency	1.0	2.06217
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24669
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45469
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50565
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K25016708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4002
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00204
Cerebrovascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68911
biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.091927
Tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
BRD-K28006645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39031
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9947
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05087
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32268
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57953
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
KYM1	CCLE Cell Line Gene Expression Profiles	1.0	2.64616
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
Coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
hsa-miR-4300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K20028734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14672
microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181827
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUBM	DepMap CRISPR Gene Dependency	1.0	6.38303
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4761
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062048
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4047
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU812	CCLE Cell Line Gene CNV Profiles	1.0	1.3885
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.59359
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77317
BRD-K80495774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33941
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47578
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25246
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58365
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MSG_FSG_FCG-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48524
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26331
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78331
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094321
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.274
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9523
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
0173570-0000-4715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14671528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28849
arthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178126
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
mantle zone of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49817
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05833
PEO4	DepMap CRISPR Gene Dependency	1.0	7.13642
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
ACSBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86662
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33798
EM2	CCLE Cell Line Gene CNV Profiles	1.0	2.11995
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73544
been	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76315
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77727
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
downregulation	GeneRIF Biological Term Annotations	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19158
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25107
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55684
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073005
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
abnormal adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
biological_process	GO Biological Process Annotations 2015	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96416
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.54271
PMC10197848-12885_2023_10795_MOESM5_ESM.xlsx-Sheet1-ESR2_overexpressing_MCF7_cells_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01865
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1851
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74551
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340019
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44634
decreased body size	MPO Gene-Phenotype Associations	1.0	null
GSE213988_0_v_1_rrm2_human	RummaGEO Gene Perturbation Signatures	1.0	null
species	GeneRIF Biological Term Annotations	1.0	null
Glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
hyperactivity	MPO Gene-Phenotype Associations	1.0	null
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61538
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27836
impaired swimming	MGI Mouse Phenotype Associations 2023	1.0	null
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32402
Liver angiosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
PMC4753639__F8	PFOCR Pathway Figure Associations 2024	1.0	null
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K48533326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32348
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3913
CRCGN012_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31027
GATA2	ChEA Transcription Factor Targets	1.0	null
mantle zone of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42357
Middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12797
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92665
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.85388
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.327
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22675
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
damage	GeneRIF Biological Term Annotations	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K22139757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06445
Tunica externa vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92966
BRD-K47555438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.697
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40695
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37112
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36633
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.969
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21635
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.830584
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.51484
NCI H226	BioGPS Cell Line Gene Expression Profiles	1.0	1.33735
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884707
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8598
acute myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105267
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.04338
hep-g2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404039
Adult body size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07369
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31512
superoxide metabolic process	GO Biological Process Annotations 2015	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123113
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ros	GeneRIF Biological Term Annotations	1.0	null
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95509
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13679
BRD-K88812218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60692
BRD-K00347903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26333
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34932
abnormal stationary movement	MPO Gene-Phenotype Associations	1.0	null
Lung cancer in ever smokers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047342
jnk	GeneRIF Biological Term Annotations	1.0	null
poor grooming	MPO Gene-Phenotype Associations	1.0	null
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32294
Pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.522
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02129
abnormal grooming behavior	MPO Gene-Phenotype Associations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.03583
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48431
MEL270	DepMap CRISPR Gene Dependency	1.0	6.23821
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.569213
BRD-K01787291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04324
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.37954
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.2028
monocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183313
pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.184086
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065465
superoxide-generating NAD(P)H oxidase activity	GO Molecular Function Annotations 2023	1.0	null
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
786	BioGPS Cell Line Gene Expression Profiles	1.0	0.853931
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Familial combined hyperlipidaemia_Blood monocyte_GSE11393	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.82042
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78645
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922781
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.211715
BRD-K07489055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00847
nox3derived	GeneRIF Biological Term Annotations	1.0	null
resveratrol	CTD Gene-Chemical Interactions	1.0	null
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05472
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JL1	DepMap CRISPR Gene Dependency	1.0	2.91075
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24654
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095412
UACC257	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.930416
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2359
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Lung adenocarcinoma_LUAD_TCGA-69-7765-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.289
superoxide metabolic process	GO Biological Process Annotations 2023	1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055596
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061022
Thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.897
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44366
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8924
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185612
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76395
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.49248
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02428
valdecoxib-6403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
BRD-K27885385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55905
NCI-H292 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213833
pathways	GeneRIF Biological Term Annotations	1.0	null
cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
PLB-985 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.776
KU-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29997
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.9853
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20274
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.15526
HMC18	CCLE Cell Line Gene Expression Profiles	1.0	3.40799
SNU-C5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.223165
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.956835
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
GATA3	ENCODE Transcription Factor Targets	1.0	null
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43054
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13371
ARRDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7842
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857819
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22298
nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217762
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.1444
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24476
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1021
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.409
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
asthma; hypersensitivity	GAD Gene-Disease Associations	1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56275
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061671
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04495
Root hair tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990073
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.722127
coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420004
UT7	CCLE Cell Line Gene CNV Profiles	1.0	1.62961
SOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5664
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.79125
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.33745
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K99016279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3467
microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183898
CARD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5173
AR	ChEA Transcription Factor Targets	1.0	null
Oxidoreductase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K23481525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43093
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34039
Organelle inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.063
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09026
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07375
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56766
superficial mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92979
intermediate part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4974
bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.098358
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34374
andor	GeneRIF Biological Term Annotations	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Neural stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0939
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866713
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superoxide anion generation	GO Biological Process Annotations 2025	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal food intake	MPO Gene-Phenotype Associations	1.0	null
BRD-K53559383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18666
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50142
paraseptal subpallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05909
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.962074
cellular process	GO Biological Process Annotations 2015	1.0	null
LY6E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92796
Vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.749
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54971
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229299
ZFP57-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
PF382	CCLE Cell Line Gene Expression Profiles	1.0	1.35039
leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.353027
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96805
GSS	CCLE Cell Line Gene Expression Profiles	1.0	2.1375
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20136
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55397
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48962
vegfa	GeneRIF Biological Term Annotations	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.25231
BRD-K38596298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01481
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328994
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055884
together	GeneRIF Biological Term Annotations	1.0	null
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50816
intracellular part	GO Cellular Component Annotations 2015	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.866094
Oily fish consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.909691
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36777
abnormal motor coordination/ balance	MPO Gene-Phenotype Associations	1.0	null
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29732
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01058
BRD-K78961368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08419
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436822
BRD-K82379643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55811
Extrinsic component of external side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48431
Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematological	GAD High Level Gene-Disease Associations	1.0	0.295739
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22736
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9975
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.051082
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953685
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.987
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56795
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.39322
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10977
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64414
CAOV4	DepMap CRISPR Gene Dependency	1.0	3.32865
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41715
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8832
COLO829	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90475
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512957
outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07088
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7236
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6541
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63916
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43988
inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04664
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923858
hearing/vestibular/ear phenotype	MPO Gene-Phenotype Associations	1.0	null
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.4
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.25509
SKB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03622
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36967
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19927
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	Reactome Pathways 2024	1.0	null
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29181
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068931
D502MG	DepMap CRISPR Gene Dependency	1.0	5.39563
K-562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17918
ACTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.429
BRD-K03213425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90084
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.33984
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.816068
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
impaired swimming	MPO Gene-Phenotype Associations	1.0	null
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.166
kinase	GeneRIF Biological Term Annotations	1.0	null
NADPH	HMDB Metabolites of Enzymes	1.0	null
superoxide	GeneRIF Biological Term Annotations	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.79133
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6385
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86725
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
phenelzine-3802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.14729
hsa-miR-3690	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055646
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.39
Brain Lower Grade Glioma_LGG_TCGA-P5-A731-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68644
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4863
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8186-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6FZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72936860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21238
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.959
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75642
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.32762
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943701
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4899-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59960811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0599
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11317
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31339
BRD-K13436682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43668
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02647
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93193
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8796
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
KALS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17371
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01454
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19084
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10163
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55684
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.147214
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
intermediate stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77032
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62708
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
BRD-K39548949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32351
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.72148
m2 part of substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47979
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55717
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71977
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07072
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4952
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-U07653185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42584
Spontaneous coronary artery dissection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
BRD-K28467592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10978
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9279
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35801
SF539	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85719
Arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2646
erythrocyte indices	GAD Gene-Disease Associations	1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96974
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96359
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29673
constitutively	GeneRIF Biological Term Annotations	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.53413
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.484
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4652
BRD-K44509164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24184
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.872
Aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
PMC12302741-40659_2025_634_MOESM1_ESM.pdf-6-TFAP2C_TFAP2C	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53089
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K69536411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64942
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.211
fenoterol-5432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69066
NDUFAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52454
BRD-K96635690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33478
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29975
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056233
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4147
Arterial endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3359
PMC4753639__F8	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K07933458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88728
Vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.95
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1261
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4434
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reactive oxygen species metabolic process	GO Biological Process Annotations 2015	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058602
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.475
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
Pulmonary emphysema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445268
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2347
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
ALOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85915
BRD-K14723547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94755
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10152
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4632
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04828
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16921
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-3.27947
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0702
Integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.022
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51363
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.462772
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
PMC8228183__F20	PFOCR Pathway Figure Associations 2024	1.0	null
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08281
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070432
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21937
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03225
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K64568504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23156
bone disease	GWASdb SNP-Disease Associations	1.0	0.130893
drive	GeneRIF Biological Term Annotations	1.0	null
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08818
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.046406
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266413
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06213
b16f0	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51053
integral	GeneRIF Biological Term Annotations	1.0	null
arthritis	GWASdb SNP-Disease Associations	1.0	0.281082
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040972
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058616
TE441T	CCLE Cell Line Gene CNV Profiles	1.0	1.46619
BRD-K70648728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83246
BRD-K07476637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36495
Smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.866
Vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10037
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40181
PMC7978298__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.078
Catalase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.054
myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187591
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08256
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901796
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.408
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24063
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48633
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08333
choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.785635
SARS-CoV MA15_Day1-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.94405
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43779
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06658
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6879
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
AR4-2J cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.875673
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15967
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11931
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30164
Cerebral infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0424
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2035
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09481
PCI-15A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal linear vestibular evoked potential	MPO Gene-Phenotype Associations	1.0	null
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95565
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
A204	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.682
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3086
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24682
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37619
PANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51284
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.888405
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
Aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62182
BRD-K93866368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08897
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.47357
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69051
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34521
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34775
Pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81043
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91451
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.246017
superoxide metabolic process	GO Biological Process Annotations 2025	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8596
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244545
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9891
BRD-K25038599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69017
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31313
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75387
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59304
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72050003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44856
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86494
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
Posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04903
BRD-K02329600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07375
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99898
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04024
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81082554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24767
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28286
BRD-K57650037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43849
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.755
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74265
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.065414
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82382
BRD-K06935782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00905
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
mantle zone of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24388
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.745
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28111
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.2156
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6793
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.59275
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
macrophage cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.370496
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07055
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K89650689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12742
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089851
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88457
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24288
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.04071
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.55855
KYO1	CCLE Cell Line Gene CNV Profiles	1.0	1.47088
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55511
BRD-K32367664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43871
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9794
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.43106
FAD	HMDB Metabolites of Enzymes	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	3.41043
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11334
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27159
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU119	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43201
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29617
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10323
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09689
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61582
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12146
Graves Disease	DisGeNET Gene-Disease Associations	1.0	null
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08638
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.32762
NFATC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03076
BRD-A73150064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2007
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24545
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17309
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6532
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
detection of abiotic stimulus	GO Biological Process Annotations 2015	1.0	null
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47151
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.46244
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943089
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
PCCL-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36397
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
ascites	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280012
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K24109044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10061
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28945
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.018
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18959
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.44665
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00423
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01551
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K53088255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06217
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03179
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79627
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2219
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARA deltaORF6_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.34521
A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.66347
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054956
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
icSARA deltaORF6_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83044
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.40714
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.5666
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4274
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97602
LN18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70974
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4752
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20441
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938177
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3674
detection of external stimulus	GO Biological Process Annotations 2015	1.0	null
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426109
BRD-K64132098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41844
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.601
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55806
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03331
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3872
NCIH2286	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16743
HUO-3N1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172673
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16111
BRD-K01975855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94835
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.05
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09331
atherosclerosis	GWASdb SNP-Disease Associations	1.0	1.30312
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
SK-N-FI	GDSC Cell Line Gene Expression Profiles	1.0	1.64033
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58592
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092979
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.9297
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041811
TYKNU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02244
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6146
myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075018
Lung squamous cell carcinoma_LUSC_TCGA-43-2578-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
NFE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
Hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.35669
CREB1_01_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.31602
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7149
generating	GeneRIF Biological Term Annotations	1.0	null
A-VN-1203-2004(H5N1)_Day4-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.24717
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82938
Lipoprotein(a)	dbGAP Gene-Trait Associations	1.0	0.629291
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.06635
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935193
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1096
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70384
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81465
BRD-K71563254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33459
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3906
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23744
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3603
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.073
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
Blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.568
A-VN-1203-2004(H5N1)_Day4-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.03702
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87401
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83276
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058907
Hypersensitivity	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367502
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52235
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.843864
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964597
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5403
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95633
FOXA2	ChEA Transcription Factor Targets	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4264
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44819
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45108
BRD-K75688794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7055
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29309
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.066519
Alveolar epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
Plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.763
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32071
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.643
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.096
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126043
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
fetal alcohol syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06102
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A689-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866713
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48994
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19327
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.342233
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2511
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TSPAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35561
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01596
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067863
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74179
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90969
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
BRD-K18601936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17565
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54051
cancer	GAD High Level Gene-Disease Associations	1.0	0.295739
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
Autosomal dominant nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
BRD-K62935946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11359
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10704
PMC4264883__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Rectum adenocarcinoma_READ_TCGA-CL-5918-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
demonstrate	GeneRIF Biological Term Annotations	1.0	null
ESR1	Hub Proteins Protein-Protein Interactions	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05762
BRD-K40841951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61764
Embryo Loss	CTD Gene-Disease Associations	1.0	1.2013
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55318
leukocyte transendothelial migration	KEGG Pathways	1.0	null
SNX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53012
absent otoliths	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OW-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04787
membrane	GeneRIF Biological Term Annotations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.985
LEVOTHYROXINE	DGIdb Drug Targets 2026	1.0	2.94067
BRD-K73357010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30366
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53823
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165655
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2495
Neointima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05046
BRD-K97256018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22268
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3739
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.547
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7383
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.32089
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
decreased	GeneRIF Biological Term Annotations	1.0	null
DNA replication factor C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
Granulomatous Disease	DisGeNET Gene-Disease Associations	1.0	null
CRCGN010_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08349
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.865
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44069
EIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44772
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22586
developmental process	GO Biological Process Annotations 2015	1.0	null
CRYBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00492
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80415
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13009
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41451
HMC18	CCLE Cell Line Gene CNV Profiles	1.0	2.77978
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4456	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.070652
BRD-K21955896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00093
BRD-K27401646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78113
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1672
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.20155
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34028
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21747
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01007
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1239
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.22725
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43321
NCI-H1688	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37712
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43127
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organelle envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.249
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81084
Hemorrhage	CTD Gene-Disease Associations	1.0	1.2861
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6526
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.74379
glycogen	GeneRIF Biological Term Annotations	1.0	null
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66513
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
BRD-K94373167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80917
GSE210101,GSE210114_11_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0519
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8429
SNU182	CCLE Cell Line Gene CNV Profiles	1.0	1.38128
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242054
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43321
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5034
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4779
Acute Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99627
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2245
protein complex	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82467
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436438
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.619442
Plasma membrane raft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.57
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86855
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53796
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22248
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.947135
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3204
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3515
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0262
Caveola	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09163
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84202
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
abnormal postural reflex	MGI Mouse Phenotype Associations 2023	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.092
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80356
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63665
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.412992
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	4.21868
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263669
PMC5463201__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20201
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49166
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
WTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70864
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17734
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74936
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.094012
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94921
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50536
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.275
Growth cone filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.103832
ZNF789	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91925
CRCGN012_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39838
regulated	GeneRIF Biological Term Annotations	1.0	null
hypertension	GeneRIF Biological Term Annotations	1.0	null
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6408
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50797
KDM5A	ENCODE Transcription Factor Targets	1.0	null
BRD-K75007044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83126
thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210589
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.55769
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33305
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01014
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86122
FaDu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95307
implicated	GeneRIF Biological Term Annotations	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.27082
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22415
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.072
Phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.259
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09414
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K93223696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22745
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67699
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61868
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
SLC2A4RG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35562
Phagolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071505
BRD-K03937692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23843
PPFIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66141
tnfalphainduced	GeneRIF Biological Term Annotations	1.0	null
Chronic Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78216
BRD-K75900905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53173
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48413
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2908
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
Mitochondrial respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072312
insulin	GeneRIF Biological Term Annotations	1.0	null
ZNF366	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58351
OVMIU	DepMap CRISPR Gene Dependency	1.0	12.9477
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92257
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08556
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0198
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1278
Ferredoxin reductase-type FAD-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U3-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952456
NCC021	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70061
Psychological distress	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57895
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Lung mucoepidermoid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2345
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33069
POLR2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04151
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842582
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.087162
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42112
GSE111247_2_v_9_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18225
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80098
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.587
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3673
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943701
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6556
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0295
Lung adenocarcinoma_LUAD_TCGA-97-A4M3-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061209
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
BRD-K88836117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34496
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.822
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9783
ESCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55855
HUT78	CCLE Cell Line Gene CNV Profiles	1.0	1.39515
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320227
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347408
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01245
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35892
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3619
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82201
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.79575
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52674
abnormal otolithic membrane morphology	MPO Gene-Phenotype Associations	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0286
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
Gastric pit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76999
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EFO27	DepMap CRISPR Gene Dependency	1.0	2.7258
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.994
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
Microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
PSN1	CCLE Cell Line Gene Expression Profiles	1.0	1.7622
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.07198
Signaling by Rho GTPases	Reactome Pathways 2024	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.598117
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0786
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96201
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69078
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03579
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.109
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	3.11316
Vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.131
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046789
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.84387
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.53411
BRD-K34209560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94925
Capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.379
edrophonium chloride-5001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LSM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63862
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13123
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.26825
Integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38805
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.161905
homeostatic process	GO Biological Process Annotations 2015	1.0	null
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58026
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3952
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0346
BRD-K13309514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6588
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4912
NANOG	ChEA Transcription Factor Targets	1.0	null
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00841
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2194
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13331
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160004
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61048
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03177
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08398
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080668
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16408
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43261169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06335
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29181
tinidazole-4370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oxygen	GeneRIF Biological Term Annotations	1.0	null
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73669
CYBC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95826
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94107
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75256
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1131
PF-01378883-00-6363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89830699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02009
BRD-K99953989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27383
Endostyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
cyba	GeneRIF Biological Term Annotations	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2882
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33294
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32952
points	GeneRIF Biological Term Annotations	1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09335
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.605
D425	DepMap CRISPR Gene Dependency	1.0	2.34453
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13345
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25259
BRD-K46715415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37463
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04708
ROS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-K93040255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65331
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9283
TAS2R5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88722
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43913
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6597
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39084
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60533
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47629
BRD-K88384015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0147
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10335
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05562
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.56527
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hpaec cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.586828
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.21506
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29445
OV-90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hereditary spherocytosis type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50555
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
Bag cell neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03438
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77335
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05391
RCOR1	ChEA Transcription Factor Targets	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.928
Necrosis	CTD Gene-Disease Associations	1.0	1.32667
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19847
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02985
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43913
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20201
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K72156149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15341
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1006
invadopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.207451
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32219
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06673
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59873
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79245
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-675-NME2_NME2	Rummagene Transcription Factor Associations 2026	1.0	null
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.921386
URM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3015
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28476
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14826
CAOV4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40389
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15036
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19579
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3016
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28964
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11081
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3907
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
Aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5304
PMC11312688__F3	PFOCR Pathway Figure Associations 2024	1.0	null
PMC7896717__F3	PFOCR Pathway Figure Associations 2024	1.0	null
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16664
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5414
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
SKNDZ	DepMap CRISPR Gene Dependency	1.0	2.37345
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19725
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.142576
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867094
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.51888
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46189
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tea consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5696
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1923
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100327
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5202
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042332
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.758615
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
matrigel	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1785
Microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
BRD-K33734659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13921
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22758
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09323
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09285
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49197
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
impaired balance	MGI Mouse Phenotype Associations 2023	1.0	null
T173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62817
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42176
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77164
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22888
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03018
Hypopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056596
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
superoxide-generating NAD(P)H oxidase activity	GO Molecular Function Annotations 2025	1.0	null
B3GNT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44969
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
BL1113 (CENPH)	NURSA Protein Complexes	1.0	null
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
POU5F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18283
BRD-K84775364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91619
abnormal head movements	MPO Gene-Phenotype Associations	1.0	null
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19262
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
BRD-K65170870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80531
Agranulocytosis	DisGeNET Gene-Disease Associations	1.0	null
496100450_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.44821
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02106
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93355
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31812476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72501
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6445
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92403
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3676
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14488
alprenolol-3188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN011_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5411
X-linked chronic granulomatous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.658
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11717
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50146114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1428
TIGAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94669
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08281
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
Perinuclear endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86065
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48598
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32411
eosinophilia-myalgia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27683
Dihydrolipoyl dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.089
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63418
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128026
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29427
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842582
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232029
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078062
functions	GeneRIF Biological Term Annotations	1.0	null
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.935
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
hl-60 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185973
BRD-K50177531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28714
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
naltrindole-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23781
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6086
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.992
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.88218
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.305
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16534
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38099
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24695
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6565
cellular	GeneRIF Biological Term Annotations	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10064
U251	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52989
BRD-K04696500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67182
methocarbamol-2274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K61134709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47623
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37291
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75712
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3065
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.844696
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42811
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.24715
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8411
infection	GAD High Level Gene-Disease Associations	1.0	0.293278
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02963
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61263
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98627
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164786
candidate	GeneRIF Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5245
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37143
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22595
93T449	DepMap CRISPR Gene Dependency	1.0	2.00428
SOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15799
NADPH oxidase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22777
nadph oxidase complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.21531
Cerebral artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.1217
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
Tracheal smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12437
BRD-K69751974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04909
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06962
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0843
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
ZNF84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36931
acute myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095234
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27683
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22244
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K96663576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68434
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
CRCGN014_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41976
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9051
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.987
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39762
absent linear vestibular evoked potential	MPO Gene-Phenotype Associations	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13454
GSE155567_2_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70072942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13963
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23604
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18026
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.46851
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
Mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
Aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039964
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.4957
raw-264.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.451042
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0612
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma	GeneRIF Biological Term Annotations	1.0	null
head tilt	MPO Gene-Phenotype Associations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2699
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
PMC4516600__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.93801
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28286
abnormal adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9515
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30611
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14315
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
circling	MPO Gene-Phenotype Associations	1.0	null
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43369
absent vestibuloocular reflex	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85519
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14117
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377245
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2243
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04868
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78378
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57331
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83171
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120204
BRD-K84233319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1006
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42297
SK-MEL-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
abnormal ear physiology	MPO Gene-Phenotype Associations	1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.22036
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953548
Mitochondrial ATP-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
decreased body size	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K30649361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68519
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2376
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17084
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.177
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3133
prevented	GeneRIF Biological Term Annotations	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.285
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	2.06463
A204	GDSC Cell Line Gene Expression Profiles	1.0	3.59617
LAMA84	CCLE Cell Line Gene CNV Profiles	1.0	1.55762
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01773
chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.190168
decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170911
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39909
F36P	CCLE Cell Line Gene CNV Profiles	1.0	1.79189
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5034
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00888
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09457
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61825
SYNCRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10287
BRD-K84574164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30185
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82113
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328628
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89617
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15979
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97162
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48255
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3744
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57735
ZDHHC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11158
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18198
RAC1 GTPase cycle	Reactome Pathways 2024	1.0	null
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42729
abnormal circadian behavior	MGI Mouse Phenotype Associations 2023	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4497
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42223
BRD-K44975377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13161
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62685
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13123
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64317
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23073
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07568
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08785
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063782
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7852
PRKDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37076
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09785
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	GO Molecular Function Annotations 2023	1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HaCaT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.99618
Lung adenocarcinoma_LUAD_TCGA-50-5049-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
CRCGN013_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1917
BRD-K33371292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42409
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10669
monocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32205
ELL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39454
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857819
models	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19295
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33817
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.009
CRCGN017_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72027
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079854
SNU-423	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	0.584275
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
CEBPZOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45379
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25612
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29292
TTLL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58425
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
butyrylcholine-cl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16158
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0746
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40246
CHK2_KD_GSE54268_668_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.66893
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7226
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63588
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2476
PMC9218220__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16024
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501574
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.46085
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81151
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2329
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02584
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Autosomal recessive nonsyndromic deafness 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
BRD-K85513726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51045
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.473
GSK3B_knockdown_208_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.83163
oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	GO Molecular Function Annotations 2025	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1378
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85196
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.063392
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.576329
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26418
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.738
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26599
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24486
Respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866094
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.037363
Autosomal recessive nonsyndromic deafness 18B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.249664
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0095
PMC7848718__F4	PFOCR Pathway Figure Associations 2024	1.0	null
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
producing	GeneRIF Biological Term Annotations	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
maturation	GeneRIF Biological Term Annotations	1.0	null
BRD-K99827210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22129
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19319
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48431
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24078
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
absent linear vestibular evoked potential	MGI Mouse Phenotype Associations 2023	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6204
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.053897
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.508635
coinciding	GeneRIF Biological Term Annotations	1.0	null
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
BRD-K31898235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64195
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
Pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80871
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96471
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866713
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56125
Pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80532
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
20460173-ImmPortAntimicrobials	GeneSigDB Published Gene Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
PMC4264883__F4	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00959
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052626
oxidase	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24533
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995301
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.583
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2646
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66477
HT	CCLE Cell Line Gene Expression Profiles	1.0	1.48226
SNU466	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34976
response to abiotic stimulus	GO Biological Process Annotations 2015	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926464
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12624
Renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071263
FUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87164
BRD-K45723655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51863
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6014
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.007
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
OC314	DepMap CRISPR Gene Dependency	1.0	3.10736
vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
SARS-CoV_12Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.66628
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63567
BRD-K90697694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75988
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2393
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
BRD-K91490997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58722
Prostate adenocarcinoma_PRAD_TCGA-J9-A52C-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NADH dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.796
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060192
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0206
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05682
BRD-K05050615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95069
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30976
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
Genetic causes of porto sinusoidal vascular disease	WikiPathways Pathways 2024	1.0	null
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15333
STAT3	ChEA Transcription Factor Targets	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.921
A_CA_04_2009_7dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60977
TBRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63961
BRD-K41709602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02464
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62649
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.54025
sirolimus-5567	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00685
absent otoliths	MGI Mouse Phenotype Associations 2023	1.0	null
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15672
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7319
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6811
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00474
Pontine reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16248
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2063
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2326
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16676
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01661
BRD-K55053106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63033
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82835
drug-induced hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.073
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3604
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23658
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9286
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05048
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6021
ALDH18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70625
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045338
roles	GeneRIF Biological Term Annotations	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5772
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23972
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0649
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069598
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14417
SKNAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52116
oxidoreductase complex	GO Cellular Component Annotations 2015	1.0	null
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.317
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38815
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03425
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4156
competent	GeneRIF Biological Term Annotations	1.0	null
adipose tissue phenotype	MPO Gene-Phenotype Associations	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4283
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57999
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39635
MSMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36099
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32382
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06397
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
BRD-K23162004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30679
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61601
METHIMAZOLE	DGIdb Drug Targets 2026	1.0	1.68038
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53074
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47832
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.129
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9324
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213746_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86903429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04604
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073828
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00512
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
BAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
BRD-K00611112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16712
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.67028
Esophageal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
cell part	GO Cellular Component Annotations 2015	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867094
LN235	DepMap CRISPR Gene Dependency	1.0	3.12374
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
Glomerular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68152
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65701
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50359
head tilt	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5687
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20058
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904985
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
fetal alcohol spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.991909
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9777
RS411	CCLE Cell Line Gene Expression Profiles	1.0	1.90627
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.29614
dld-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235457
NKX3-1	JASPAR Predicted Transcription Factor Targets	1.0	null
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52091
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30999
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93849
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05819
jerky movement	MGI Mouse Phenotype Associations 2023	1.0	null
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79562
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34608
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63473
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
FBXW8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69278
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.06406
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03927
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10323
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0694
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.505102
BRD-K23553911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53595
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66742
BRD-K86452395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80692
superoxide anion generation	GO Biological Process Annotations 2023	1.0	null
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13104
CD164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9396
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73945
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9649
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177029
SMU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62264
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.632
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21281
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.98317
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9212
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
SH4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67037
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14364
BRD-K05057860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06006
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049894
Microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.368
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3332
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.376
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.62132
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26643
BRD-K89951364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27967
DAOY	CCLE Cell Line Gene CNV Profiles	1.0	1.61324
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGF1_OE_GDS3484_540_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.034
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0704
EP300	ENCODE Transcription Factor Targets	1.0	null
Coffin-Siris syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19027
BRD-K10684867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24441
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45358
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853566
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21153
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0536
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11608
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17217
icSARA deltaORF6_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4623
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27683
NDUFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97147
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
POU3F2	ChEA Transcription Factor Targets	1.0	null
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4872
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256234
HNF4A	ChEA Transcription Factor Targets	1.0	null
hepatic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.37592
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884707
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70325
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1615
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857819
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64317
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82519
Otitis interna	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.56351
T47D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG-75	GDSC Cell Line Gene Expression Profiles	1.0	1.46138
impaired coordination	MPO Gene-Phenotype Associations	1.0	null
methylergometrine-6704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48431
ZNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3823
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4554
asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.124707
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
PMC9209555-12288_2021_1474_MOESM1_ESM.docx-0-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.673335
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3325-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.08444
impaired coordination	MGI Mouse Phenotype Associations 2023	1.0	null
superoxide-generating nadph oxidase activity	GO Molecular Function Annotations 2015	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04509
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.56359
BRD-K43915000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.08452
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1881
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867094
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.119048
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110817
PCTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57195
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1366
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24716
NADPH oxidase complex	GO Cellular Component Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61416283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36736
GSE81193_0_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stereotypic behavior	MPO Gene-Phenotype Associations	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9144
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	2.04765
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ADHD and autism ASD pathways	WikiPathways Pathways 2024	1.0	null
hsa-miR-4521	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.109
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42045
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7796
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21875
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
CA46	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Erythrocyte Indices	dbGAP Gene-Trait Associations	1.0	0.139944
C19orf84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00858
Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A2780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75993
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16369
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
nephropathy	GeneRIF Biological Term Annotations	1.0	null
reactive	GeneRIF Biological Term Annotations	1.0	null
Crohn Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
include	GeneRIF Biological Term Annotations	1.0	null
UACC-257 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04684
Vasculature	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.877
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71726
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77418
BRD-K76431854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65504
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.76244
Podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96962
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4469
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19373
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0622
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35595
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075881
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.014
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31639
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.512
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57156
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5093
ZUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93778
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37403
HPAFII	DepMap CRISPR Gene Dependency	1.0	2.04263
skmel31	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.03779
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.8519
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3728
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34942
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49777
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58322
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.416
Integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.82
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03342
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55736
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4199
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
absent vestibuloocular reflex	MPO Gene-Phenotype Associations	1.0	null
Cytosolic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
BRD-K85527716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42483
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51006
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24005
BRD-K44713204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16649
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null