association	dataset	threshold value	standardized value
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.395235
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2351
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.35798
Perturb_4130_KO_Fmr1_SRP212786	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.69353
plasmon	GeneRIF Biological Term Annotations	1.0	null
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51346
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.730807
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9045
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6568
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70429
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38291
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62852
cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03264
BMI1	ChEA Transcription Factor Targets	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06238
PKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85161
regulation of reactive oxygen species metabolic process	GO Biological Process Annotations 2015	1.0	null
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3589_KO_DDX6_ERP024006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.8477
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93976
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106625
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9919_KD_MATR3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.7752
Perturb_17281_KO_Gja1_SRP247546	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.97247
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.06919
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906567
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26364
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06086
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8494_KD_U2AF1_SRP221683	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.72903
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19176
MAVER1	DepMap CRISPR Gene Dependency	1.0	2.53974
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51651
leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581218
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signet ring cell adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.692296
Perturb_12704_KO_LIPA_SRP310406	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.6897
Perturb_2760_KD_CBX3_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.75849
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36692
Perturb_14155_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3983
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362773
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.64517
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82745
Perturb_3646_KO_HDAC1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.6129
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
extracellular structure organization	GO Biological Process Annotations 2015	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11818
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76736
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18438
Perturb_4668_KO_Wdr5/Trp53_SRP324834	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.4348
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05508
Perturb_3634_KO_NEAT1_DRP008265	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.738
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44423
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37869
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63929
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45268
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219928
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34334
PSMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44051
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27092
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7378_KO_PHF3_ERP112687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.29586
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03525
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2373_KO_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.87541
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.39263
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.937338
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.15515
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
chronic granulomatous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.697911
BRDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11372
Perturb_9906_KD_RO60_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.65979
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RHO GTPases Activate NADPH Oxidases	Reactome Pathways 2024	1.0	null
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.902
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1269
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233472
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.4332
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88683
Perturb_444_KD_AKR1B1_SRP121474	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.78828
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.322922
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32406
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.60664
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.29715
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94423
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44772
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93361
Hypertrophy	CTD Gene-Disease Associations	1.0	1.37446
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72607
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_146_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54113
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58914
Cerebrovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.2365
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44292
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203604
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atrial fibrillation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
Femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Cecum cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.648533
biological_process	GO Biological Process Annotations 2015	1.0	null
skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10742
abnormal vestibular labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
STON1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13697
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26591
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869391
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057321
WiDr cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.333
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35721
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34665
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.883981
BE2M17	DepMap CRISPR Gene Dependency	1.0	3.86615
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40523
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05122
Perturb_7336_KD_SUGP1_SRP286876	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.41722
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7367_KD_H2BC21_SRP308810	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.47452
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_10008_KD_HNRNPU_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.02627
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17614_OE_FOXP2_SRP225889	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.853
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Supplementary_Table_2F_Contrast_ATF4-def_IGG_8h_vs_HCT116_IGG_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32363
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83754
KE37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40918
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47892
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.809
Perturb_7692_KD_UPF1_SRP240357	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.84985
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8253095-MOL2-15-1942-s005.xlsx-gene_lists-Genes_associated_with_H3K27ac-positive_sample_selective_AR_sites_AR	Rummagene Transcription Factor Associations 2026	1.0	null
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.083204
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HUG1N	CCLE Cell Line Gene Expression Profiles	1.0	1.47091
TCF12	ENCODE Transcription Factor Targets	1.0	null
Perturb_6737_KD_PAF1_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.47995
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26848
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18982
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26837
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A7UZ-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
step	GeneRIF Biological Term Annotations	1.0	null
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tracheobronchial epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
SUZ12	ENCODE Transcription Factor Targets	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
Perturb_14652_KD_Ctr9_SRP297013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.13372
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
Perturb_10051_KD_PRPF8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.0161
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
Perturb_2068_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.25471
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31055
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44636
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83225
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.956727
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0305
HCT116	DepMap CRISPR Gene Dependency	1.0	2.98534
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	CCLE Cell Line Gene Expression Profiles	1.0	1.40069
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.026
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stereotypic behavior	MPO Gene-Phenotype Associations	1.0	null
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52252
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834727
disruption	GeneRIF Biological Term Annotations	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.454369
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_96_KI_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.15302
Perturb_14375_KD_IGF2BP1_SRP291710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34864
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900966
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
involves	GeneRIF Biological Term Annotations	1.0	null
Perturb_5649_KD_MYBL2_SRP161768	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.6983
GSE182834,GSE182836_2_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853639
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.02774
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95403
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47092
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.17497
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
cellular_component	GO Cellular Component Annotations 2015	1.0	null
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46902
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64414
Perturb_3913_KD_Y14_SRP118481	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21554
Perturb_15108_KD_MPP8_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.80446
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13860_KD_TBX2_ERP107244	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.70464
MAZ	ENCODE Transcription Factor Targets	1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62471
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.78125
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52253
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
Perturb_12674_KD_Sox10_SRP191908	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.41289
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18341
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03095
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952501
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.48343
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71068
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Right colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06063
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.38754
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.51585
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.38068
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4355
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875397
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.902
fetal alcohol spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.647743
Perturb_17316_KO_Tardbp_SRP321767	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.2989
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0173
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824013
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87824
abnormal ear morphology	MPO Gene-Phenotype Associations	1.0	null
HUNS1	DepMap CRISPR Gene Dependency	1.0	3.62776
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.529519
ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44771
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.893212
epithelial	GeneRIF Biological Term Annotations	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
homolog	GeneRIF Biological Term Annotations	1.0	null
Perturb_8486_OE_PLXNB2_SRP282509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.2665
cellular component organization	GO Biological Process Annotations 2015	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01905
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081997
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15774
22RV1	DepMap CRISPR Gene Dependency	1.0	3.40035
Perturb_3651_KO_RIPK1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.8587
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
RHO GTPase cycle	Reactome Pathways 2024	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16209
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3624
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854231
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45213
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gna14	GeneRIF Biological Term Annotations	1.0	null
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
agonist	GeneRIF Biological Term Annotations	1.0	null
Perturb_13569_KD_Crebl2_SRP214575	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.17276
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01767
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.824327
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10195
Perturb_17545_KD_EFB1_SRP357509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colon	HPA Tissue Gene Expression Profiles	1.0	1.31522
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23955
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70429
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_9648_KD_TCF7L2_SRP327946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.32828
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7488_OE_RAMP2_SRP169097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.64183
CHD1	ENCODE Transcription Factor Targets	1.0	null
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060277
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35932
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of reactive oxygen species metabolic process	GO Biological Process Annotations 2023	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266335
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20027
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22149
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8757
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92592
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50638
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.993121
USF1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MG-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921625
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11966
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082783
Perturb_14632_KD_MSI2_SRP067129	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.93122
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.96587
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57562
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of respiratory burst	GO Biological Process Annotations 2015	1.0	null
resting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06559
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37186
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.751
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00535
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
IB3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.0633
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986035
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
NOXA1	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30196
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41592
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
hepatic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.418394
liver	GTEx Tissue Gene Expression Profiles	1.0	1.02743
stimulates	GeneRIF Biological Term Annotations	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0572
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.922483
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84697
Perturb_2901_KD_HDAC1_SRP327853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.30801
BCL3	ENCODE Transcription Factor Targets	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.17027
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1492
Perturb_6945_KO_Xirp2_SRP259323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.15648
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9781
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374528
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
HKBMM	DepMap CRISPR Gene Dependency	1.0	2.35176
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
capan2	HPA Cell Line Gene Expression Profiles	1.0	1.24309
LO68	DepMap CRISPR Gene Dependency	1.0	2.77423
resonance	GeneRIF Biological Term Annotations	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11524
Perturb_16605_KO_Bend2_SRP357909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82135
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11351
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6918
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTUD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42318
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.08655
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066953
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14152_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.5229
gastric	GeneRIF Biological Term Annotations	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.5641
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23528
nadph oxidase complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01654
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06615
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80258
Perturb_11926_KO_SKI_SRP125960	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.29483
Weight Gain	CTD Gene-Disease Associations	1.0	1.35012
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.921199
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.08
Perturb_2576_KD_LINE1_ERP011233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.53603
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9536
consisting	GeneRIF Biological Term Annotations	1.0	null
SARS-BatSRBD_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60597
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.615
abnormal otolith morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76509
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.538893
conformational	GeneRIF Biological Term Annotations	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051208
KAT2A	ENCODE Transcription Factor Targets	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.968464
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
invadopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.526341
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
preferred	GeneRIF Biological Term Annotations	1.0	null
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	1.37543
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tracheal smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9689
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844587
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.992313
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3619_KO_SMARCA4_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.62724
vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_6260_KD_NDP_SRP188348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.02436
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
Perturb_11402_KD_CPT1A_SRP076884	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.48016
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14774
betapix	GeneRIF Biological Term Annotations	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_32_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01162
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.615
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7957
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25803
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045378
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12676_KO_PTPN2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38367
OE33	DepMap CRISPR Gene Dependency	1.0	2.01823
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15753
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6739
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10318
oxidases	GeneRIF Biological Term Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62931
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18653
MIN6-N8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
Histiocytic lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	Reactome Pathways 2024	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886422
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926305
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-1.17497
Tetradecanoylphorbol Acetate	CTD Gene-Chemical Interactions	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Perturb_9963_KD_MTPAP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.89656
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75298
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37756
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76619
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_3640_KO_BRD4_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.5724
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23797
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25782
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
Tracheobronchial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.653019
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.974959
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89275
Perturb_10165_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.77545
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.584244
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pneumonia	CTD Gene-Disease Associations	1.0	1.50498
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
Perturb_638_KD_GATA3_SRP372594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.13511
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.37561
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56309
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.6494
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.663555
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.06314
Perturb_6435_KD_HOXA10AS_ERP131886	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.72812
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03834
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824362
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.43696
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.913507
Perturb_13928_OE_DLG2_ERP119345	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.0523
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06086
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08899
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06238
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JB-23-ZE86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218484
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51519
Perturb_71_KD_LINE1_ERP011233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.71815
major	GeneRIF Biological Term Annotations	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95803
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.744627
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
TGFBR1	Hub Proteins Protein-Protein Interactions	1.0	null
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14811
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.289
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11185
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22919
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.311145
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tumorigenesis	GeneRIF Biological Term Annotations	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_51_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11404_OE_HNF1A_SRP081517	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.92917
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.385143
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00206
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
absent otoliths	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90157
ATF2	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0622
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.949962
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.481258
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061669
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_7313_KO_UPF3A_ERP130416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.0953
Perturb_6872_KD_YAP1/WWTR1_SRP323378	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.91807
thr341	GeneRIF Biological Term Annotations	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54345
HDAC3_KO_GDS4886_66_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99719
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.106725
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2412
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.977616
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26016
Arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34642
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62227
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC549	DepMap CRISPR Gene Dependency	1.0	4.80403
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02907
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66Y-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04249
GSE185872_0_v_2_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80878
IB-56-BR35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230744
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460305
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29663
CTCF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08574
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01636
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.6151
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heart	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
GSE190186,GSE190188_0_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981485
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74571
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69601
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37744
ACOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40562
Perturb_9719_OE_Wt1_SRP126738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.34202
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.25999
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62931
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5561-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-1.17497
NADPH oxidase complex	GO Cellular Component Annotations 2025	1.0	null
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIPRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78437
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
COLO201	CCLE Cell Line Gene Expression Profiles	1.0	1.57888
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9272
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
superoxide metabolic process	GO Biological Process Annotations 2023	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68968
abnormal motor coordination/ balance	MPO Gene-Phenotype Associations	1.0	null
PLB-985 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.1566
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27993
regulation of reactive oxygen species metabolic process	GO Biological Process Annotations 2025	1.0	null
hacat	HPA Cell Line Gene Expression Profiles	1.0	1.02737
nmr	GeneRIF Biological Term Annotations	1.0	null
Perturb_4942_OE_MLL1_SRP190074	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7746
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NR0B1	ChEA Transcription Factor Targets	1.0	null
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16021
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642454
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59535
Integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2464_KD_SETDB1_SRP344480	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.43139
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5741
Hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
Poisoning	CTD Gene-Disease Associations	1.0	1.08584
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.059
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.824
HPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Skin mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.03
PMC9730246-Table_7.xlsx-LPS_Val_up-Upstream_Regulator_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.02077
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847755
Perturb_2059_KD_CHERP_SRP354316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.62482
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41658
choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824431
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83884
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1048
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70277
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02439
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991804
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_NFIA-Logfold_change_threshold_1_0_1_NFIA	Rummagene Transcription Factor Associations 2026	1.0	null
ACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92729
allows	GeneRIF Biological Term Annotations	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949163
Perturb_11546_KD_PRKAA1_SRP303942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.30339
Intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.511
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Barrett's esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
ARID3A	ENCODE Transcription Factor Targets	1.0	null
Asymmetric Septal Hypertrophy	DisGeNET Gene-Disease Associations	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.553069
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17531_KO_CD44_SRP256345	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.56711
Intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15211
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.902
Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
catalytic complex	GO Cellular Component Annotations 2015	1.0	null
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	1.5117
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91169
DCTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67181
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24251
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
HT-29 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.554
GSE147613_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992384
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6445
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51293
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.27057
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6777_KD_BRD4_ERP024018	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.29836
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291674
RCOR1	ENCODE Transcription Factor Targets	1.0	null
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11507
Hydrogen peroxide	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02638
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20328
SP1	ENCODE Transcription Factor Targets	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cytosolic	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
HS939T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88115
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frank-Ter Haar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
HS281T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6301
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.29049
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Supplementary_Table_2B_Contrast_ATF4-def_DMSO_2h_vs_HCT116_DMSO_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29087
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98066
496100360_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29285
PMC4270131__F10	PFOCR Pathway Figure Associations 2023	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26974
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29982
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3528
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991804
interleukin-23 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.456809
Perturb_8495_KD_U2AF1_SRP221683	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.0782
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28509
Cochlear labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70292
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80368
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHT101	DepMap CRISPR Gene Dependency	1.0	2.98109
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular component disassembly	GO Biological Process Annotations 2015	1.0	null
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95031
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.998066
PMC4270131__F10	PFOCR Pathway Figure Associations 2024	1.0	null
Phagocyte bactericidal dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.952
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00026
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78414
Ebolavirus(ZEBOV)_6day_PBMCs_rhAPCtreated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.023664
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.41002
Perturb_13601_KD_YAP1_SRP337871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.89378
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50954
Perturb_7328_KO_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.54856
Perturb_9918_KD_MAGOH_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.54135
PMC4019409__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059543
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.438
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34327
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.82752
HDAC3_KO_GDS4886_29_mouse_heart - 6 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC3342315-pone.0036054.s011.xlsx-overlap_PBX1_ChIP_siRNA-Unnamed_5_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84697
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.924771
Edema	CTD Gene-Disease Associations	1.0	1.12461
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GB2	DepMap CRISPR Gene Dependency	1.0	2.33938
experiments	GeneRIF Biological Term Annotations	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28478
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72719
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32547
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.27344
phosphatidylinositol binding	GO Molecular Function Annotations 2015	1.0	null
BT549	DepMap CRISPR Gene Dependency	1.0	5.75392
regulation of hydrogen peroxide metabolic process	GO Biological Process Annotations 2025	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.438
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44479
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841441
extracellular matrix disassembly	GO Biological Process Annotations 2023	1.0	null
induction	GeneRIF Biological Term Annotations	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ING4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71641
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70665
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.31446
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
lm5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4496
gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.743954
Perturb_9407_KD_GATA6AS_SRP279802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.72639
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04495
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24687
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
assignments	GeneRIF Biological Term Annotations	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98306
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00094
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7288_KD_FTO_SRP070463	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49502
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
regulation of respiratory burst	GO Biological Process Annotations 2023	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.80082
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
abnormal membranous labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
core of nucleus accumbens	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09385
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950553
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSV-A2_24Hour-B6.129PF1_J_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.89784
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
ADAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07543
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06342
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.70252
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.63103
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829834
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.38489
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Necrosis	CTD Gene-Disease Associations	1.0	1.56828
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15276
PMC8481886-Table_1.xlsx-A_subsets-iMSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.11372
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
Mitochondrial ATP-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
MITF	ChEA Transcription Factor Targets	1.0	null
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
NCIH810	CCLE Cell Line Gene CNV Profiles	1.0	2.88415
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
ZWILCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61297
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.956271
superoxide metabolic process	GO Biological Process Annotations 2015	1.0	null
Pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9823
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307889
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84119
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47449
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.67398
circling	MPO Gene-Phenotype Associations	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
A7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.10664
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826919
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947441
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	GeneRIF Biological Term Annotations	1.0	null
colon	GTEx Tissue Gene Expression Profiles	1.0	0.893964
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.081312
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2813300-pone.0008960.s011.xls-SOX2_squamous_signature-Gene_Symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_7597_KO_TENT3A/TENT3B_SRP400572	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.9385
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49713
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6397
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.764072
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958536
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862868
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949843
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung mucoepidermoid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36154
Perturb_1159_KD_CELSR2_SRP149837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.87249
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7051
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-37-GD83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272687
Perturb_401_KD_RNF113A_SRP201913	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60986
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.502357
PMC4697333__F5	PFOCR Pathway Figure Associations 2023	1.0	null
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34581
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive chronic granulomatous disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Perturb_1324_KD_RBM39_SRP301121	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
phosphorylation	GeneRIF Biological Term Annotations	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
part	GeneRIF Biological Term Annotations	1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73226
Lung squamous cell carcinoma_LUSC_TCGA-66-2794-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19681
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03941
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073682
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01025
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41317
Perturb_3667_KO_FASTKD_SRP277516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_13324_KD_Junb_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.93294
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352425
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
KC-26-JQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343025
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.0186
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.26821
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.21507
Perturb_2348_KD_IRF1_SRP381930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.93129
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.824
Perturb_13655_KO_TAPR1_SRP291201	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.67115
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10099_KD_HNRNPU_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1154
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872046
cell part	GO Cellular Component Annotations 2015	1.0	null
Perturb_13923_KD_DDX5/DDX17_SRP335223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43552
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09076
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28305
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08489
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54679
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU1196	DepMap CRISPR Gene Dependency	1.0	2.24776
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93201
Perturb_4327_KO_Zcchc8_SRP187429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.11344
SNU5	DepMap CRISPR Gene Dependency	1.0	2.68406
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4190_KO_Dnmt3a_SRP300442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.39772
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.34648
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970535
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46839
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Perturb_4695_KD_Srsf3_SRP059321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.72059
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886422
Perturb_6434_KD_HOXA10AS_ERP131886	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.54671
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04662
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.063
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.30993
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00982
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stalk cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0765
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.563741
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33349
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
MM383	DepMap CRISPR Gene Dependency	1.0	2.79881
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03743
Lung adenocarcinoma_LUAD_TCGA-78-7152-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_79_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_86_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A8YN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
LSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09075
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.29024
Perturb_6939_KD_EP300_SRP068733	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.67117
Red cell distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60092
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72938
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integrin alphaIIb-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
BMI1-19503595-MEFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
Perturb_6141_OE_PPP1CA/PPP1R8_SRP118980	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.512
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.80034
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17911
circling	MGI Mouse Phenotype Associations 2023	1.0	null
ptdins345p3	GeneRIF Biological Term Annotations	1.0	null
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270464
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
AR	ChEA Transcription Factor Targets	1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48042
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66273
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06696
HT29	CCLE Cell Line Gene Expression Profiles	1.0	2.20512
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69828
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.592232
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.00005
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
Perturb_14288_KD_ALKBH5_SRP272155	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31009
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sufficiently	GeneRIF Biological Term Annotations	1.0	null
acetate	GeneRIF Biological Term Annotations	1.0	null
ISCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37153
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Atrophic gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
SLR25	CCLE Cell Line Gene CNV Profiles	1.0	1.86967
U343	DepMap CRISPR Gene Dependency	1.0	5.51219
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Perturb_17263_KO_Gja1_SRP247546	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.5084
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41383
IDH3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69418
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27715
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92172
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_110_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22487
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BT16	DepMap CRISPR Gene Dependency	1.0	2.41636
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30255
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.311145
MYC-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
C11orf71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18014
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844277
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7699_KD_SKIIP_SRP155347	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.09436
TGFBR1	Pathway Commons Protein-Protein Interactions	1.0	null
786O	DepMap CRISPR Gene Dependency	1.0	2.10443
EP300	ENCODE Transcription Factor Targets	1.0	null
Perturb_2054_KD_CHERP_SRP354316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.25614
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MF-11-EW49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283607
critical	GeneRIF Biological Term Annotations	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.56378
Perturb_8919_KD_ARID1A/P300_SRP256204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.37017
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.38754
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3008
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10318
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0791
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Perturb_14149_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.6438
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.917428
Gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833968
Perturb_13342_KD_Smarce1_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.5262
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27802
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42857
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60521
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898374
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923342
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046762
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2021
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	Reactome Pathways 2024	1.0	null
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53911
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
SH3 domain	InterPro Predicted Protein Domain Annotations	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	2.13707
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63232
PMC12122724-41467_2025_60028_MOESM6_ESM.xls-Supplementary_Table_4_Marker_g-Supplementary_Table_4_Marker_genes_of_six_TPIT_tumor_subtypes_TBX19	Rummagene Transcription Factor Associations 2026	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927062
Mitochondrial respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.751
Perturb_13609_KD_Srrm3/Srrm4_SRP136943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44168
RAD21	ENCODE Transcription Factor Targets	1.0	null
Perturb_7154_OE_MOV10_SRP029367	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.1656
Perturb_15634_KO_AHCY_SRP351305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.56447
Perturb_772_KD_SRRM2_SRP366559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.63271
Infertility, Female	CTD Gene-Disease Associations	1.0	1.16001
regulate	GeneRIF Biological Term Annotations	1.0	null
Autolysosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
regulation of hydrogen peroxide metabolic process	GO Biological Process Annotations 2023	1.0	null
Knrk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
EPDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09955
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18511
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067994
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.592232
extracellular matrix organization	GO Biological Process Annotations 2015	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.824
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59809
interleukin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.446465
change	GeneRIF Biological Term Annotations	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0166
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913126
Perturb_13855_KD_IGF2BP1_SRP284043	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.83
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
model	GeneRIF Biological Term Annotations	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4288
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92529
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37184
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
transcripts	GeneRIF Biological Term Annotations	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_1216_KO_Klf16/Zfp580_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.7466
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872136
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
need	GeneRIF Biological Term Annotations	1.0	null
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.927
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16593
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888203
hif2a_16565084_mcf7_lof_human_gpl2507_gds2761	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.17094
Perturb_398_KD_WTAP_SRP039397	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60248
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.51652
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17058
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43367
Perturb_9899_KD_EIF3G_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.37671
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
regulators	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25371
generation	GeneRIF Biological Term Annotations	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239307
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
Perturb_2395_KD_TRIM28_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6447
Perturb_9970_KD_WDR43_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.76529
HLMVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516891
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6702
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.752
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63935
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pulmonary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.167
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_7_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885271
Congenital generalized lipodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06238
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.847484
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
Perturb_12703_KO_LIPA_SRP310406	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.56862
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19575
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2586_KD_RORC_SRP066204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.90732
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.133
Perturb_3642_KO_DNMT1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.50807
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18381418-Table1	GeneSigDB Published Gene Signatures	1.0	null
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2627
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6361
Perturb_15423_KD_PXN_SRP199368	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.2038
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86335
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
hearing/vestibular/ear phenotype	MPO Gene-Phenotype Associations	1.0	null
Mitochondrial respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.765
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8306625__F1	PFOCR Pathway Figure Associations 2024	1.0	null
rin5f	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
Perturb_8125_KD_LARP4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.10866
Lung endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.307
pparg_21068720_macrophage_c57bl6_lof_mouse_gpl1261_gds4370	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.44534
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.927
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28545
A-Vietnam-1203-2004(H5N1)_2day-wtC57BL-6J_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.44188
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.68263
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061876
SMARCA4	ChEA Transcription Factor Targets	1.0	null
p47phox	GeneRIF Biological Term Annotations	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886422
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5241
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
cellular component disassembly	GO Biological Process Annotations 2025	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.19999
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5468
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35982
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EGR3_01_212	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59057
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.919488
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25698
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59607
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.16933
Perturb_6302_KD_JMJD1A_SRP248223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.61542
rectum	HPA Tissue Gene Expression Profiles	1.0	1.13824
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53993
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.845729
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.37561
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DCP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22866
Carcinoma, Signet Ring Cell	DisGeNET Gene-Disease Associations	1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.218
TIA1_KO_GSE54418_264_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_7156_KD_ARID1B_SRP366384	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02402
hsa-miR-192-5p	MiRTarBase microRNA Targets	1.0	null
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90446
Perturb_14373_KD_IGF2BP1_SRP150935	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34864
Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96174
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51743
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.927
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60674
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957329
MAFK	ENCODE Transcription Factor Targets	1.0	null
Perturb_5658_KO_SA2_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.65577
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0288
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7155_KD_ARID1A_SRP366384	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.6925
DD-34-TT70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228514
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20624
ERBB2_druginhibition_7_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67517
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54711
Perturb_7423_KD_DKC1_SRP045222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.95757
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44693
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.8205
PMC10201771-12864_2023_9385_MOESM1_ESM.xlsx-ST18-Unnamed_11_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12547
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75271
Perturb_5044_KO_Ssu72_SRP167695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.2518
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367321
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
phagocyte bactericidal dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.678701
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06791
excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4h-LAS1L_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51053
CREB1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05594
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
Perturb_7566_OE_NUDT21_SRP327319	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.27348
Perturb_8755_KD_SON_SRP300475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66627
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
Rectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33018
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.982024
Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphorylated	GeneRIF Biological Term Annotations	1.0	null
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
Perturb_13868_KD_KDM6B_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1192
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.582176
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.720996
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30101
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830305
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_8895_KD_FGD5_SRP281196	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43693
Colonic adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958536
Perturb_13874_OE_LIN28B_SRP225128	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.78266
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_7355_KO_NSUN6_SRP233222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.09304
transfected	GeneRIF Biological Term Annotations	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08746
Perturb_6794_KD_PAF1_SRP060227	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.80226
BAD-BCL-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Perturb_7300_KO_SF3A1_SRP273617	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.9911
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73922
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10766
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07837
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64275
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831495
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06238
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.61561
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42795
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838237
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.432618
Perturb_10044_KD_EFTUD2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.02536
Perturb_3649_KO_MTF2_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.4964
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67982
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04255
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of respiratory burst	GO Biological Process Annotations 2025	1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95002
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50836
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14761
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66425
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PROX1_01_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60897
Perturb_4378_KD_MALT1_SRP127318	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.69362
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX2-21211035-GBM-HUMAN-BRAIN-GLIOBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175146
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38236
TNF alpha signaling	WikiPathways Pathways 2024	1.0	null
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.32949
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.75685
Perturb_4531_KD_Senp6_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31375
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
PMC3824607__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.9081
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04695
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22333
Perturb_10093_KD_XRCC6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.7015
OBSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28666
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1402
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_15427_KD_RB1_SRP145071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.44074
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887477
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7866-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887477
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Arterial endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
Perturb_2074_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.41215
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15436
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65843
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
Tunica media vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myristate	GeneRIF Biological Term Annotations	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.3465
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65Z-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28469
ptdins45p2	GeneRIF Biological Term Annotations	1.0	null
nadph oxidase complex	GO Cellular Component Annotations 2015	1.0	null
Ecabet	DrugBank Drug Targets	1.0	null
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.011
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.56819
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
participates	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09444
Nanog_KD_GDS1824_134_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
Lung epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.441
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41525
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926938
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846328
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080893
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.601092
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81535
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.945495
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824604
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22314
SSB_02_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.35614
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73A-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042548
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.641643
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2898
MBD4	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35045
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90798
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
Perturb_13949_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.83583
Glutathione synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15429_KD_BRCA2/RB1_SRP145071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.45301
Neointima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.467
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
Perturb_14879_KO_H14_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.85928
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170025
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345558
extracellular matrix organization	GO Biological Process Annotations 2025	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.49977
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMARCA4-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
phorbol	GeneRIF Biological Term Annotations	1.0	null
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.93384
PHETA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96446
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20454
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pulmonary Fibrosis	CTD Gene-Disease Associations	1.0	1.18293
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87602
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33107
UACC-257 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242672
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	8.32885
Perturb_2990_KO_UTX_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.15647
Perturb_3644_KO_EIF2AK3_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991804
CCLP1	DepMap CRISPR Gene Dependency	1.0	2.33114
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.62136
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.596
PMC6393772__F2	PFOCR Pathway Figure Associations 2024	1.0	null
ME-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NADPH oxidase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.878779
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.751
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05819
HDAC1	ENCODE Transcription Factor Targets	1.0	null
altered righting response	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466111
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85904
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046592
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.927
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU478	DepMap CRISPR Gene Dependency	1.0	3.33499
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7S9-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17583_KO_Bap1_ERP016523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.01132
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.09878
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13346
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.821
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33541
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38247
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68194
Arterial endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991804
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
IRAK2_knockout_76_GSE24264	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29891
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.65449
HS274T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54608
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51827
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4019409__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_15098_KD_PDHA1_SRP385600	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.61341
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02047
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843208
Smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.746
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
Perturb_9841_KD_KDM6A_SRP254623	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2854
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070006
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30715
RHO GTPase Effectors	Reactome Pathways 2024	1.0	null
Fetal alcohol syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Perturb_3645_KO_EP300_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.60774
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19469
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YBX3_02_98	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.9622
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.34991
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
RAC1 signaling pathway	PID Pathways	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_11733_KD_Dstyk_SRP396092	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.1947
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.4336
Inflammation	CTD Gene-Disease Associations	1.0	2.04124
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158951
MMDD1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16171
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_2567_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.23352
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
head tilt	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12174
PRKCA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14745_OE_MEOX2_SRP330486	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.74726
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40399
Perturb_8716_KO_DHRS4AS1_SRP370273	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.58394
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.596
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_7397_KD_DHX38_ERP132987	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.36234
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62719
PMC4697333__F5	PFOCR Pathway Figure Associations 2024	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU601	CCLE Cell Line Gene Expression Profiles	1.0	1.96727
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34525
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16102
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077332
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
nox3	GeneRIF Biological Term Annotations	1.0	null
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
abnormal placing response	MGI Mouse Phenotype Associations 2023	1.0	null
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.976425
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71641
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56138
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88834
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.6476
Perturb_13948_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.79903
Vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.082
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superoxide metabolic process	GO Biological Process Annotations 2025	1.0	null
RPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12568_KD_Sufu_SRP194252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11588
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46014
Perturb_9106_KD_SNHG12_SRP223778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.62665
Perturb_7314_KO|KD_UPF3A_ERP130416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.0444
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24426
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.04723
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.96986
Perturb_3605_KO_ARID1B_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08807
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.013
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.02102
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.977257
Perturb_7157_KD_NEAT1_SRP366384	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00768
Perturb_7714_OE_IL25_SRP405857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.04068
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.4017
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47898
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Lung Injury	CTD Gene-Disease Associations	1.0	1.37846
Perturb_3513_KD_RNPS1_ERP107441	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.91242
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3471
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30138
Perturb_10097_KD_CNOT8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.73454
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40986
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12079
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34819
JHUEM7	DepMap CRISPR Gene Dependency	1.0	5.11054
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7147
Perturb_7558_Mut_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.97181
U251MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68617
Perturb_7316_KO|KD_UPF3A_ERP130416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.13325
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09848
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.42795
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18679
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921625
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25637
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_545_KD_CT_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.80349
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.792
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561644
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85879
superoxide-generating NADPH oxidase activator activity	GO Molecular Function Annotations 2025	1.0	null
Perturb_15515_KD_E2F2_SRP314859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.75287
Artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.603
Vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.944
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03775
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.047
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.962198
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7911_KO_LIN52_SRP367036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.73341
Perturb_4732_KO_Ssu72_SRP167695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.5768
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25051
PIP4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35204
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74088
death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050909
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_129_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3824607__F3	PFOCR Pathway Figure Associations 2024	1.0	null
HLA-E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06223
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.37561
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09218
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
using	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.45486
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08126
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10218
right colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.15695
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14874_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68442
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
backbone	GeneRIF Biological Term Annotations	1.0	null
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.34697
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.489327
nox1	GeneRIF Biological Term Annotations	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.085
DNA replication factor C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
Perturb_3637_KO_BLVRB_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.93882
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882525
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861578
H3K36me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77213
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.05131
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
mediated	GeneRIF Biological Term Annotations	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35584
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_735_KD_PAF1_SRP048744	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.8791
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27702
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988911
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.688817
Perturb_5162_KD_Mbd2_SRP051519	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.67251
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23086
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.694946
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82319
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7924
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283921
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
egfinduced	GeneRIF Biological Term Annotations	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50396
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988228
USF2	ENCODE Transcription Factor Targets	1.0	null
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
Left colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.985704
PMC6393772__F2	PFOCR Pathway Figure Associations 2023	1.0	null
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44548
MXI1_02_173	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.1964
H3K79me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	2.58095
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.342233
skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.685463
Perturb_6845_KO_ABCE1_SRP244437	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.78356
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t47d	HPA Cell Line Gene Expression Profiles	1.0	0.839654
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998649
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57693
FOS	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1563	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35616
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.751
J-774 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
Perturb_10138_KO_PRPF40B_SRP197235	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.6468
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.298
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.4922
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6553
Perturb_13905_KD_DAZAP1_SRP102807	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.08698
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13208
Perturb_7315_KO_UPF3A_ERP130416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04374
KATO-III cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06344
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200839,GSE233826_2_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Podosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
Organelle envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LS-174T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11692_KD|OE_SF3A3|MYC_SRP253943	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.9356
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.467273
Perturb_14359_KD_BUB3_SRP057074	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.40668
Perturb_3636_KO_BAZ2A_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.7432
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7948_KD_SKIIP_SRP155347	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.76429
Perturb_3638_KO_BRD2_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.35932
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.85618
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13334
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76485
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900966
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_268_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	3.89508
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.751
Autosomal recessive nonsyndromic deafness 18B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952248
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42286
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGFR1_mutant_26_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.94513
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982495
VSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25278
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_131_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_1218_KO_Zbtb7a/Zfp580_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.5712
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
Perturb_7533_KO_HDLBP_SRP255633	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.37631
Perturb_3668_KO_FASTKD_SRP277516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.1662
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.77994
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44974
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853228
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.903715
adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.115629
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276019
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07393
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20911
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.65594
Killing mechanisms	Reactome Pathways 2024	1.0	null
EFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95468
Perturb_10108_KD_EIF4A3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.95906
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63001
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158434
Perturb_7544_OE_ALPG_SRP277076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.1898
ING2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35527
erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
Perturb_7950_KO_BAZ1A_SRP100570	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.58876
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.867658
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040039
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20338
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86697
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_771_KD_SRRM1_SRP366559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.89149
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73625
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.982988
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
impaired balance	MGI Mouse Phenotype Associations 2023	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_7292_KI_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.15302
Perturb_7625_KD_ICE1_SRP120604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.183
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5527_OE_Uprt_ERP106180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.29612
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
identify	GeneRIF Biological Term Annotations	1.0	null
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86613
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64832
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2520_KD_JUN_SRP357624	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.47602
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53367
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042767
GMS10	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31141
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042572
Cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73859
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47658
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13449
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64871
Perturb_7425_KD_RBFOX2_SRP045481	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.82065
myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358174
MXI1	ENCODE Transcription Factor Targets	1.0	null
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69814
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.992254
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30251
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20442
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12239_KO_ZMYND8_SRP130942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49486
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.601
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.723
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.69597
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79351
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.601
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62112
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973008
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14836
spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54569
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25618
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824893
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891404
Perturb_9108_KD_STAT3_SRP363695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.4166
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855856
SLC66A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18322
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7537_KD_RREB1_SRP265233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.8125
RAC1 GTPase cycle	Reactome Pathways 2024	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74757
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nox	GeneRIF Biological Term Annotations	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.193
Perturb_16464_OE_Zfp36_SRP255505	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82252
abnormal stationary movement	MPO Gene-Phenotype Associations	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42632
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07818
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160435
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.10613
Perturb_9112_KD_STAT3_SRP363695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.52284
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52794
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06589
Perturb_15635_KO_MAT2A_SRP351305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SORD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10678
RFX5	ENCODE Transcription Factor Targets	1.0	null
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914152
Perturb_8205_KD_PCBP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.60538
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44231
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.954317
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855093
Perturb_15379_KD_NSD2_SRP269000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.98204
rectum_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.859502
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37288
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.14324
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72938
Perturb_2078_OE_PUM2_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.03132
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54621
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34087
WM2664	DepMap CRISPR Gene Dependency	1.0	2.8068
Perturb_860_KO_Tsga8_SRP254760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nadph oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.62945
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853882
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15918
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.751
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34772
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.8261
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4158
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gastric epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42171
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27899
SW948	DepMap CRISPR Gene Dependency	1.0	3.95885
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32097
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39148
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38821
Ecabet	HMDB Metabolites of Enzymes	1.0	null
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CHD7	ENCODE Transcription Factor Targets	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73448
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4547
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.367
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	2.86663
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00249
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84664
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.21304
SAP30	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.633622
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06238
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.899198
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19015
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_6763_KO|KD_SERPINE2_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.25565
interactions	GeneRIF Biological Term Annotations	1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7379_KD_SMG5_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.82435
Pancreatic islet cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17064
metabolic process	GO Biological Process Annotations 2015	1.0	null
H-508	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
Perturb_7327_KO_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.2035
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
rostral group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987998
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75027
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8226_KD_EWSR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.07365
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-215-5p	MiRTarBase microRNA Targets	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59646
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15527_OE_CPT1A_SRP292168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.71597
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.13833
Intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.707
Perturb_520_KD_RNF113A_SRP201913	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.80497
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990663
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67006
studied	GeneRIF Biological Term Annotations	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_downregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16259
Perturb_7534_KO_HDLBP_SRP255633	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.38545
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14893_KO_H11_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.91108
trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186149
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.18151
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.84825
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
Vasculature	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.789
IRF1	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07279
Perturb_14357_KD_SOX2_SRP341440	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31252
impaired balance	MPO Gene-Phenotype Associations	1.0	null
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23072
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
targets	GeneRIF Biological Term Annotations	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.981851
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33881
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04329
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32471
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
without	GeneRIF Biological Term Annotations	1.0	null
Perturb_7837_KO_AGO1_SRP136692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.5165
Fibrosis	CTD Gene-Disease Associations	1.0	1.07482
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.413622
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
embryonic	GeneRIF Biological Term Annotations	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887477
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_8920_KD_P300_SRP256204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.02382
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901509
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.813946
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.25
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRO-AP2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Perturb_7181_OE_MAGEA11_SRP216417	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70121
PMC4832872__F3	PFOCR Pathway Figure Associations 2024	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264696
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09791
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34709
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24092
RSRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14915_KD_Mof_SRP060636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9382
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAAX-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29654
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106882
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25222
Oxidoreductase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7298_KD_PCIF1_SRP162223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.03914
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13691
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_6711_KD_STAU1_SRP266909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.63064
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229839
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972968
oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.108038
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21529
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.751
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.93
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5326
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4812
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08502
Aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.895232
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14335
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.159
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
family	GeneRIF Biological Term Annotations	1.0	null
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07961
regulation of metabolic process	GO Biological Process Annotations 2025	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32045
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.259
regulation of hydrogen peroxide metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_36_KD_RBPJ_SRP151852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.56444
PMC3342315-pone.0036054.s011.xlsx-overlap_PBX1_ChIP_siRNA-Unnamed_6_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0622
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07435
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23604
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.53492
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12961
Fertilization envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38255
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27507
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03405
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839104
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	1.0	1.47915
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334498
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52012
caco-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.609332
Perturb_764_KD_SRRM2_SRP366559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.5349
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991804
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.37561
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87404
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189049
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01905
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
enzyme binding	GO Molecular Function Annotations 2015	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.083
Esophageal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
PANC0504	CCLE Cell Line Gene Expression Profiles	1.0	1.7643
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887477
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330094
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1919
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.751
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66698
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9821_KD_MYB_SRP103740	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.30275
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NOX1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10052_KD_RPS19_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.1638
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40121
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13013
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.424
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70744
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Perturb_14875_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.69279
MERO41	DepMap CRISPR Gene Dependency	1.0	2.69533
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1561
localizations	GeneRIF Biological Term Annotations	1.0	null
Perturb_7429_KO|KD_RBFOX2|HNRNPM_SRP068106	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.5205
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_86_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_18453_KO_LTR7YB_SRP194102	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.77328
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00608
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12515692-MOL2-19-2882-s001.xlsx-Phosphoproteome_AKT2_KD_vs_SCR-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.63247
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	5.26782
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26404
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.689
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
Perturb_5833_KO_Hnrnpl_SRP042164	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.33139
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	2.03117
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22477
Perturb_9544_KO_Ucp1_SRP187003	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.97689
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gastritis	DisGeNET Gene-Disease Associations	1.0	null
BRCA1_DEPLETION_GDS3791_38_human_Hela	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46206
Perturb_3530_KD_circCDKN2BAS1_SRP252917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.49964
lipid binding	GO Molecular Function Annotations 2015	1.0	null
HSF2_01_78	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.03909
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7416_KD_METTL14_SRP040278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.1321
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5843
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.75317
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91392
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909711
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5054
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METRNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01755
Lung adenocarcinoma_LUAD_TCGA-J2-A4AG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2961
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51174
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.657054
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886481
NB69	DepMap CRISPR Gene Dependency	1.0	2.36143
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01681
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066087
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17432
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_78_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16836
MYC	ChEA Transcription Factor Targets	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_119_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	2.70731
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.824
Vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.108
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255567
kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51905
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62022
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946208
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37169
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887477
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34811
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290009
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.17908
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_5563_KO_KDM4C_SRP375293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.91713
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1901
GSE250089_0_v_3_epcam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DLD-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81503
Perturb_7410_KD_HNRNPU_SRP010280	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49901
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7001
single-organism process	GO Biological Process Annotations 2015	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.321
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042222
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_88_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57156
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93489
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
noxo1	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
likely	GeneRIF Biological Term Annotations	1.0	null
extracellular matrix disassembly	GO Biological Process Annotations 2025	1.0	null
SNU182	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51973
GSE197342_1_v_0_berberine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3327
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866788
GSE149075_8_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_411_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2ES-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868575
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
made	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54739
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
MM160113	DepMap CRISPR Gene Dependency	1.0	5.67944
NKIRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84298
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.436
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33235
PMC7719303__F2	PFOCR Pathway Figure Associations 2023	1.0	null
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53223
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0692
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53438
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57201
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99122
Infertility, Male	CTD Gene-Disease Associations	1.0	1.18587
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.91101
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Perturb_5393_KD_LIM1_SRP402415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.73014
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K2-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917406
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21824
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14776
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969521
Perturb_2387_Mut_ASXL2_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.68874
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3629_KO_HDAC3_SRP355605	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.64203
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal otolithic membrane morphology	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.596
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221793
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.938327
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825934
t-84 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
GSE112714_2_v_1_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.39702
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.413901
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100292_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42455
Perturb_5661_KO_ID2_SRP336141	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.1643
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.259
Perturb_537_KD_MYBL2_SRP161768	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.361
Esophageal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20041
E2F4	ENCODE Transcription Factor Targets	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
BAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053543
Perturb_11426_KD_PRMT1_SRP357238	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.21553
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30537
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.881836
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053368
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.902092
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16508
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10394
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2073_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.60242
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5641_KD_MYBL2_SRP161768	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38745
esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.375743
CHD2	ENCODE Transcription Factor Targets	1.0	null
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MORCPR	DepMap CRISPR Gene Dependency	1.0	2.53873
TFAP2C	ChEA Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92847
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.57399
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_AsPC1-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
tnfalphatnfr1	GeneRIF Biological Term Annotations	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36347
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.848
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
PLEKHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36139
cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53267
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.486
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
absent otoliths	MPO Gene-Phenotype Associations	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6449
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84697
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6194
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
DV90	CCLE Cell Line Gene Expression Profiles	1.0	2.17715
Perturb_5482_KD_Ctnnb1_SRP130920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.9671
activate	GeneRIF Biological Term Annotations	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.913456
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25883
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
Perturb_2458_KD_ESR1_SRP268806	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862871
interact	GeneRIF Biological Term Annotations	1.0	null
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149218
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
ion binding	GO Molecular Function Annotations 2015	1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58853
saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366754
TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19911
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245491
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12517
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5008
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29732
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24215
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53425
abnormal placing response	MPO Gene-Phenotype Associations	1.0	null
LYRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26797
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14866
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72719
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860728
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37959
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80395
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.41915
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.821
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18338247-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10853_KO_Mkp1_SRP169858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84591
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10296
GSE158431_5_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49886
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.518573
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40951
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44711
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4147
esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12399
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9966_KD_SF3A3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.12655
members	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20104
oxidoreductase complex	GO Cellular Component Annotations 2015	1.0	null
kinase	GeneRIF Biological Term Annotations	1.0	null
Perturb_8331_KD_METTl14_SRP167173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.03939
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834673
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41786
Perturb_4886_KD_WTAP_ERP019668	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.46802
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63546
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
NADPH oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.994
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7865_KO_SDE2_SRP239880	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97203
SKMEL2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52355
Perturb_9923_KD_PTBP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.90103
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38821
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01062
RAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1043
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16667_KO_Tet2/Tet3_SRP056118	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.57136
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34028
thyroid gland	HPA Tissue Gene Expression Profiles	-1.0	-1.01551
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
17660535-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	4.41684
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85944
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55053
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15127
MM253	DepMap CRISPR Gene Dependency	1.0	4.54495
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
noxa1	GeneRIF Biological Term Annotations	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
Arterial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE157383_6_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59942
SNU1040	CCLE Cell Line Gene Expression Profiles	1.0	1.51085
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56732
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17699
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00019
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.24779
SNU201	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58918
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8485_KO_PLXNB2_SRP282509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.89456
TRMT10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
Perturb_10027_KD_APOBEC3C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.18559
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55251
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06142
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97967
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69176
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_15186_KD_CPSF1_SRP186931	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.49365
alternatively	GeneRIF Biological Term Annotations	1.0	null
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16208
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15223
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_10045_KD_EIF3D_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.96714
ATP5PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08071
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.799
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58684
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8103
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392554
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30135
Colonic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0248
regulating	GeneRIF Biological Term Annotations	1.0	null
lipids	GeneRIF Biological Term Annotations	1.0	null
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.73897
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20517
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Supplementary_Table_2A_Contrast_ATF4-def_control_vs_HCT116_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6901
surface	GeneRIF Biological Term Annotations	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_7587_KO_ALKBH5/FTO_SRP362871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61454
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20133
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CAV3_KO_GDS3533_17_mouse_mammary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lung	HPA Tissue Gene Expression Profiles	-1.0	-0.86661
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57524
colonic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00894
GSE203158_12_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NADPH oxidase complex	GO Cellular Component Annotations 2023	1.0	null
Perturb_14935_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
appendix	HPA Tissue Gene Expression Profiles	1.0	1.15007
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44548
intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.902
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_12521_KD_MITF_SRP190868	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.39591
superoxide anion generation	GO Biological Process Annotations 2025	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.193
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34052
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03043
PMC7978298__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01567
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23078
Chronic granulomatous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.99
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08441
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.047
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.821
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.927
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
Aortic root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
ASB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58364
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66503
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.60635
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31678
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.596
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35584
16717027-Table2	GeneSigDB Published Gene Signatures	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.81
impaired righting response	MPO Gene-Phenotype Associations	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.838672
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91832
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333028
Perturb_8142_KD_MATR3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.63647
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19225
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43931
Perturb_7801_KD_PAF1_SRP064356	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.75557
hek	GeneRIF Biological Term Annotations	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.80168
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.902
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11885_KO_Stat3_SRP307561	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7674
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54648
Perturb_5792_KO_Gzma_SRP284215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.08361
Trachea-serous cell of epithelium of trachea	Tabula Sapiens Gene-Cell Associations	1.0	-0.0517451
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.47124
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8650509__F4	PFOCR Pathway Figure Associations 2024	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52635
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
Perturb_13885_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.36789
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16386
RB_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.09732
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5084
MYOG	ENCODE Transcription Factor Targets	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68248
Signaling by Rho GTPases	Reactome Pathways 2024	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.5003
reactive oxygen species metabolic process	GO Biological Process Annotations 2015	1.0	null
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49819
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464561
Perturb_3650_KO_PI4KB_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE181959_1_v_0_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00414
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944807
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4356
1C9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
GSE129772_2_v_1_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.34753
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54723
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.922234
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855589
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03026
Perturb_13240_KO_Lamtor1_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.6282
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880998
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.896249
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38812
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4222
CRIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59414
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
extracellular matrix disassembly	GO Biological Process Annotations 2015	1.0	null
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.90936
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.37561
Perturb_15099_KD_SREBF2_SRP385600	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.45496
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42769
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80623
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10061014-Table7.XLSX-C_vs_L-Table_S7a_Predicted_upstream_regulators_of_genes_showing_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16805
ELMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51616
Umbilical cord cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.26026
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.16954
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2797_KD_RORC_SRP066204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.39749
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92985
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206317
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
Oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.726
Perturb_15328_KO_Uxt_SRP274268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.63543
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30808
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94542
rectum_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.943405
Perturb_2546_KD_EZH2_SRP067706	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.9148
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colonic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.048
TCCPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.40965
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23797
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.5028
GABPA	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839439
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14407_KD_PGK1_SRP252531	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.92397
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08512
abnormal postural reflex	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14564
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35624
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myeloid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11091
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865991
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03985
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93471
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893054
enzyme activator activity	GO Molecular Function Annotations 2015	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2573
SMC3	ENCODE Transcription Factor Targets	1.0	null
Phox homologous domain	InterPro Predicted Protein Domain Annotations	1.0	null
Pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.523
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4304
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1145
KYSE510	CCLE Cell Line Gene Expression Profiles	1.0	1.65095
NRL_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.39448
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SUSA	DepMap CRISPR Gene Dependency	1.0	3.53781
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.15478
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.871149
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30632
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11698
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_3_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2071_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.96813
gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347408
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.53146
CAV3_KO_GDS3533_357_mouse_mammalian glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
CCKBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48358
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
PMC8530322-pone.0258316.s002.xlsx-GG_778_TH17-AA_778_TH17-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94687
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.842261
Blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.706
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94216
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5564_KO_KDM4C_SRP375293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.66924
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909013
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12327
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7008
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13275
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.068
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.707
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30895
esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282837
COA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10489
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26831
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692493
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68748
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59185
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16233
cellular component disassembly	GO Biological Process Annotations 2023	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.61968
Complete generalized lipodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_8764_KD_SLIT2_SRP158939	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.65979
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076302
Perturb_10067_KD_EIF3A_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.49113
GSE114258_3_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83973
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
atrophic gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.793771
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83871
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834257
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_7291_KI_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.699
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92437
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418099
Perturb_7205_KD_U2AF1a/U2AF1b_ERP006200	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.54609
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_17620_KO_MLLT6_SRP245883	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
IM95	DepMap CRISPR Gene Dependency	1.0	2.23198
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAC3 GTPase cycle	Reactome Pathways 2024	1.0	null
KARPAS-299 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16201
Perturb_627_KD_USO1_SRP278225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.94849
LPS6	DepMap CRISPR Gene Dependency	1.0	3.7602
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944566
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31377
Perturb_11547_KD_PRKAA1/PRKAA2_SRP303942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.12498
Perturb_7535_KD_HNRNPL_SRP264981	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62928
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06684
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70663
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925343
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74845
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15725
MNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35743
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48247
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.610941
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24681
TBP	ENCODE Transcription Factor Targets	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.99454
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52881
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.132422
JA-79-II25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215022
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54677
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17560_KD_EFB1_SRP357509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079991
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991804
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16717027-Table1	GeneSigDB Published Gene Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.742
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.49499
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059739
abnormal inner ear morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_3766_KD_lincDUSP_SRP111736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.14551
Perturb_14649_KD_Paf1_SRP297013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.4645
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
oxidoreductase complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.005272
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16926
Perturb_3591_KO_DDX6_ERP024006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Catalase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.759
CEP95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78202
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.055
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nitric-oxide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.274
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43577
Perturb_2734_KD_BCKDK_SRP298085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.20298
Perturb_6206_KD_UBF_SRP188861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.85851
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.037
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39574
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.193
Ileocolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051748
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.62246
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular matrix organization	GO Biological Process Annotations 2023	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
p67phox	GeneRIF Biological Term Annotations	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2556
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5267
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53372
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14886_KO_H13_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.5221
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11674
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Vallate papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Colorectal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
Perturb_8235_KD_PCBP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.019
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04346
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01818
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.6461
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00117
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9725_OE_PCX_SRP255647	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.2683
HNF4A	ChEA Transcription Factor Targets	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MERO14	DepMap CRISPR Gene Dependency	1.0	2.08442
Perturb_7210_KD_U2AF1b_ERP006200	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.85228
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286736
Perturb_13220_KO_Atxn7l3_SRP269420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.37881
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212936
ELF1	ENCODE Transcription Factor Targets	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65209
Ventral surface of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26637
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79818
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267791
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977448
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54754
Chronic pulmonary heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
shows	GeneRIF Biological Term Annotations	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Perturb_14779_KO_PGRB_SRP309208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65251
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09576
HMGN3	ENCODE Transcription Factor Targets	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IM95	CCLE Cell Line Gene Expression Profiles	1.0	2.79506
BMI1-19503595-MEFC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	2.66354
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.838412
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18126
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839835
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF296	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49781
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44556
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.634256
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
presented	GeneRIF Biological Term Annotations	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.2647
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.956172
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7092
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Superoxide dismutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02606
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tunica externa vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86457
KPNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15409
Perturb_12580_OE_STK32B_SRP261296	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.10186
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31042
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.76
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8297
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48724
ECGI10	DepMap CRISPR Gene Dependency	1.0	2.26307
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.926502
quantitative	GeneRIF Biological Term Annotations	1.0	null
Perturb_9399_KD_MYCN_SRP104120	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.86946
Infectious disease	Reactome Pathways 2024	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963618
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991804
kidney	GeneRIF Biological Term Annotations	1.0	null
GSE236437_0_v_1_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37675
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.727494
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9924_KD_RBM22_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.02147
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48964
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04134
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6054
LS180	CCLE Cell Line Gene Expression Profiles	1.0	1.7243
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gastric pit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTURN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26158
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959979
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
Endothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.083478
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13449
superoxide anion generation	GO Biological Process Annotations 2023	1.0	null
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39878
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.65114
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.85261
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26115
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47175
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
membranebound	GeneRIF Biological Term Annotations	1.0	null
Perturb_10112_KD_FXR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_10034_KD_PUF60_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.081
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_95_KI_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.699
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13150_KD_Atoh8_SRP241825	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5358
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0499
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17437
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66599
Perturb_7390_KO|KD_UPF3A_ERP130415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
head tilt	MPO Gene-Phenotype Associations	1.0	null
Large_Intestine-immature enterocyte	Tabula Sapiens Gene-Cell Associations	1.0	6.47533
superoxide-generating NADPH oxidase activator activity	GO Molecular Function Annotations 2023	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847391
characterization	GeneRIF Biological Term Annotations	1.0	null
impaired righting response	MGI Mouse Phenotype Associations 2023	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7188
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86881
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906567
organelle envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178588
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissue	GeneRIF Biological Term Annotations	1.0	null
Nuclear envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4375
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.7727
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
ros	GeneRIF Biological Term Annotations	1.0	null
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14819
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12726_KO_MITF_SRP255094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.73204
Perturb_5188_KO_Xpo5_SRP109172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.53991
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23943
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41266
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13346
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64294
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23294
WNT5:FZD7-mediated leishmania damping	Reactome Pathways 2024	1.0	null
vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281776
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04663
Perturb_3635_KO_ATAD2_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.90511
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48191
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10766
Perturb_15521_OE_proL1_SRP277452	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.7092
Parasitic Infection Pathways	Reactome Pathways 2024	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45432
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19797
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287447
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58441
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36707
PMC4832872__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.522011
AGO1_02_95	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.10852
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937198
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051003
Carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
Perturb_5447_KD_MED1_SRP395995	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.66678
Perturb_4245_KD_GATA3_SRP372594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.52635
T-84 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-2.03484
site	GeneRIF Biological Term Annotations	1.0	null
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887477
ROS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14671
Integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.514
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18613
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7838_KO_AGO1_SRP136692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.33185
RCM1	CCLE Cell Line Gene Expression Profiles	1.0	1.74708
PMC7719303__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8763_KD_ROBO1_SRP158939	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.12447
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23198
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.5826
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06141
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87753
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55643
Esophagus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.865835
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.047
fetal alcohol syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.712796
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924083
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74725
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
PBX1	ChEA Transcription Factor Targets	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.329084
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.4968
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Resting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.606
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.764882
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RASGRF1_KD_GDS2816_287_human_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27623
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.344
roles	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60697
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16743
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECV-304 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	257.515
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1552
Perturb_7563_KD_UPF1_SRP322775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.66722
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17613_KI_FOXP2_SRP225889	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_7364_KD_CLTA_SRP308810	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.99771
rbm15_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.029609
CYBA	Pathway Commons Protein-Protein Interactions	1.0	null
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96923
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3776
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.75227
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33752
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66303
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6071
496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08067
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054537
PMC7978298__F1	PFOCR Pathway Figure Associations 2023	1.0	null
ONS76	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46737
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059762
Perturb_8390_KO_Ssu72_SRP167695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.2047
Perturb_256_KD_KLF6_SRP150445	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.26831
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07362
Perturb_3653_KO_UCHL1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7423
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23224
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.38504
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
Perturb_9929_KD_TARDBP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.74354
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CACO-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
Lung Diseases	CTD Gene-Disease Associations	1.0	1.28518
S9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adult respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.824
Perturb_9854_KD_LUC7L3_ERP124746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.26011
MTA3	ENCODE Transcription Factor Targets	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.51961
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13208
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_50_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998381
functions	GeneRIF Biological Term Annotations	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76152
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.65746
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979177
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933446
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6612
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17551
HE-22-JR80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282365
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.391141
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25581
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02927
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.924012
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R2-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastric adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0466
thioredoxin-disulfide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.307
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC2	ChEA Transcription Factor Targets	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937692
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78207
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
RI1	DepMap CRISPR Gene Dependency	1.0	2.10099
Perturb_14287_KD_TENT4A_SRP237261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.74614
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34916
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17228
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969059
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878927
Perturb_12911_KD_MDC1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.62158
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
BACH1	ENCODE Transcription Factor Targets	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995518
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60743
Perturb_14841_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.76373
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31585
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826805
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12015
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53571
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
different	GeneRIF Biological Term Annotations	1.0	null
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34306
20140255-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10030_KD_EIF4G2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.29151
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.768
Plasma membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.573
CAKI2	CCLE Cell Line Gene CNV Profiles	1.0	1.46807
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1161
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.05607
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.717882
Perturb_10120_KO_RNH1_ERP021688	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.1431
Plasma membrane raft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.632
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13953_OE_lncNR2F1_SRP179994	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.82915
formation	GeneRIF Biological Term Annotations	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935754
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23797
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02567
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Caveola	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.635
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.29824
SNU410	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70413
colonrectum_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.1576
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872046
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
superoxide-generating nadph oxidase activator activity	GO Molecular Function Annotations 2015	1.0	null
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00567
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
catalytic complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00185
Perturb_9116_KD_SMAD6_SRP252947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.45099
Perturb_16721_KO_Brca1_SRP094855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.04368
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7062
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	2.40867
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18244
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gastric epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
nuclear envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.375818
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11507
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63641
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
Perturb_9884_KD_DDX47_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.7447
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048881
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608124
Perturb_7457_KO_DHX36_SRP120502	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.37663
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
products	GeneRIF Biological Term Annotations	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58129
inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309335
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.99953
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
Perturb_9830_KD_USP7_SRP256243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.19372
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.385143
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
Perturb_3607_KO_BCL11A_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48045
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.752263
TAF1	ENCODE Transcription Factor Targets	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.557
PARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36899
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21616
Smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.034
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053168
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38485
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_432_KD_RPAP3_DRP004966	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.70353
RFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72842
FNDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13707
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ser154	GeneRIF Biological Term Annotations	1.0	null
COV434	DepMap CRISPR Gene Dependency	1.0	2.02391
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04253
EGR1	ENCODE Transcription Factor Targets	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
Perturb_8781_KO_DNMT3A/DNMT3B_SRP186642	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.44673
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
BECKER	CCLE Cell Line Gene CNV Profiles	1.0	1.37338
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38296
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15348_KD_SMARCD3_SRP329316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86427
Gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.262
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_97_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ott1_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.029609
Perturb_2394_KD_PRKDC_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.06069
Leishmania infection	Reactome Pathways 2024	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28082
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_17242_KD_IRF1_SRP337933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.56275
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
PMC10290283-biol-2022-0622-sm3.pdf-334-TET1_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.484
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.193
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
X-linked chronic granulomatous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_12304_KO|OE_EZH2|HOTAIR_SRP062995	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.59082
Perturb_4922_KD_WTAP_ERP019668	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.9074
GGPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27174
Colonic epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
p22phox	GeneRIF Biological Term Annotations	1.0	null
primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.083556
Perturb_13518_KD_ILF2_SRP077068	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.36625
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.89059
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.31036
Perturb_13863_KD_TBX2/MYCN_ERP107244	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.83954
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06297
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.989101
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2110	DepMap CRISPR Gene Dependency	1.0	2.01095
spliced	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal head movements	MPO Gene-Phenotype Associations	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7039-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS411N	CCLE Cell Line Gene Expression Profiles	1.0	1.47458
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17617_KO_TIP60_SRP386872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.5725
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
leading	GeneRIF Biological Term Annotations	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45906
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.12085
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35759
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cor pulmonale	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
CHUK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0418
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59256
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
promotes	GeneRIF Biological Term Annotations	1.0	null
Perturb_7321_KD_METTL14_SRP064870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.1321