association dataset threshold value standardized value KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.90503 NCIH2106 CCLE Cell Line Gene Expression Profiles -1.0 -2.48092 H3K79me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Adenohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.469 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphnode BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.12473 GPCR ligand binding Reactome Pathways 2024 1.0 null MDA-MB-436 COSMIC Cell Line Gene Mutation Profiles 1.0 null TOP2B_drug inhibition_GSE1417_341_human_HeLa GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC7029484-13041_2020_561_MOESM3_ESM.xlsx-Table_S8-Table_S8_The_extracted_upregulated_genes_in_SBMA-MNs_in_GSEA_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K59130962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.03276 cell part LOCATE Curated Protein Localization Annotations 1.0 null BRD-K28429328 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.05969 CRCGN017_MCF10A.WT.HP_24H:K23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.7577 BRD-K75745696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40706 CRCGN017_MCF10A.WT.HP_24H:H07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.0858 Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCGB3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72848 BRD-K04875192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.9397 Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN014_HEPG2_24H:A20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.487 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.344079 H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null BRD-K41025232 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30998 BRD-K24848743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3013 TOLEDO CCLE Cell Line Gene Expression Profiles 1.0 1.40959 BRD-K23430114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06643 BRD-K94088690 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00568 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00523 BRD-K83645749 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06641 H2BK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K34604637 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35825 BRD-K09454191 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43749 BRD-K86884344 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26223 BRD-K04631545 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6927 peripheral GeneRIF Biological Term Annotations 1.0 null BRD-K94903598 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44318 Habenular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.71 CRCGN012_HEPG2_24H:O03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.62897 neuropeptide GeneRIF Biological Term Annotations 1.0 null CRCGN016_MCF10A.TP53.M_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.72372 BRD-K78596805 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04644 GSE193258,GSE193259_5_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4277 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20I-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.075879 496100501_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05868 BRD-K65932559 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08575 pretectal region Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40105 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU668 CCLE Cell Line Gene Expression Profiles -1.0 -1.85692 SYK_knockdown_191_GSE54065 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.54175 NCIH1618 CCLE Cell Line Gene Expression Profiles -1.0 -1.45627 RERFLCKJ CCLE Cell Line Gene Expression Profiles 1.0 1.40205 BRD-K92928918 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35807 CRCGN014_HEPG2_3H:H05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.79774 RBBP5 ENCODE Transcription Factor Targets 1.0 null BRD-K22405104 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42041 BRD-K59188100 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00803 CRCGN009_HEPG2_24H:O03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.49285 CRCGN014_HEPG2_24H:J15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.75175 HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.94917 brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07577 BRD-K57404319 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10938 CRCGN014_HEPG2_24H:N09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.16853 KRAS.AMP.LUNG_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null CLDN1_OE_GDS3510_393_human_CL1-5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CRCGN014_HEPG2_24H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.16806 Dentin sensitivity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.332 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.17026 calvarium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.423054 BRD-K80575072 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.91661 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28479 Inhibin B complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.889 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.089392 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.280717 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K43364707 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18951 Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEL CCLE Cell Line Gene CNV Profiles -1.0 -1.33565 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15938 E2F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6218 CBX8 ENCODE Transcription Factor Targets 1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.2418 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K06772291 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08611 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980409 integral component of membrane GO Cellular Component Annotations 2015 1.0 null NCIH1734 CCLE Cell Line Gene CNV Profiles -1.0 -1.36566 Myelencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.429 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07405 BRD-K87658102 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01958 KDM2B-26808549-CHIP-SEQ-DND41-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CRCGN015_HEPG2_48H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.7473 496100481_PCx_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43224 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.851589 GSE193258,GSE193259_2_v_4_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null CRCGN015_HEPG2_48H:K07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.94935 CRCGN010_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.88785 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38321 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null synaptic transmission GO Biological Process Annotations 2015 1.0 null g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null BRD-K93491540 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12098 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19743 NCIH28 CCLE Cell Line Gene Expression Profiles 1.0 1.43538 BRD-K60937893 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.41812 external segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.922703 AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888412 GCIY CCLE Cell Line Gene CNV Profiles -1.0 -1.72095 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07922 BRD-K53662389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.39483 BRD-K89687419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47668 BRD-K09721867 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81899 CRCGN015_HEPG2_48H:O11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.01205 signaling GO Biological Process Annotations 2015 1.0 null CRCGN017_MCF10A.TP53.M_24H:A13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.07264 SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32017 BRD-K68364310 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.09132 CRCGN014_HEPG2_24H:A03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.56357 BRD-K22487336 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.02914 BRD-K76350099 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15416 BRD-K62807053 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37474 receptor activity GO Molecular Function Annotations 2015 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null BRD-K50004365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0008 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null KYSE140 CCLE Cell Line Gene CNV Profiles -1.0 -1.57766 GABRD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48147 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927452 SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.993982 BRD-K57517066 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.69711 HCC89 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63564 BRD-K10481024 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1203 HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.02162 glomerulosa GeneRIF Biological Term Annotations 1.0 null HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33569 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.74966 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.951 CRCGN009_HEPG2_24H:F20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.4119 CRCGN009_HEPG2_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.02073 Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.2 E2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0385 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46658 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14338 BRD-K07336866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23756 midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.367876 CRCGN009_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.95675 gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.59404 plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null cortex GeneRIF Biological Term Annotations 1.0 null ZNF384 ENCODE Transcription Factor Targets 1.0 null SKBR3 DepMap CRISPR Gene Dependency 1.0 2.71412 BRD-K40419401 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24786 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.957483 OCUM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K37865854 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44095 SNUC1 DepMap CRISPR Gene Dependency 1.0 4.90859 H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KMS28BM CCLE Cell Line Gene Expression Profiles 1.0 2.2529 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN012_HEPG2_24H:D07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5398 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055399 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46138 BRD-K44834268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12538 GPCRs class A rhodopsin like WikiPathways Pathways 2024 1.0 null TM31 CCLE Cell Line Gene CNV Profiles -1.0 -1.72173 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050428 ventrolateral prefrontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06788 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2241 CCLFUPGI0005T DepMap CRISPR Gene Dependency 1.0 2.02951 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03442 outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49721 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.995572 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K75869048 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09865 CRCGN012_HEPG2_24H:D08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.05957 MALME 3M BioGPS Cell Line Gene Expression Profiles 1.0 1.23874 NPW Pathway Commons Protein-Protein Interactions 1.0 null preoptic area TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.248361 Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.342 regulation of biological process GO Biological Process Annotations 2015 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13181 CRCGN014_HEPG2_24H:L13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.10843 plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043346 KMS11 CCLE Cell Line Gene Expression Profiles -1.0 -1.68687 BRD-K37931645 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18019 MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29277 Breast - Mammary Tissue GTEx Tissue Gene Expression Profiles 2023 1.0 2.92832 GSE140937,GSE140938_0_v_2_slfn11_human RummaGEO Gene Perturbation Signatures 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33569 BRD-K77875023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02417 EZH2 ENCODE Transcription Factor Targets 1.0 null BRD-K52634604 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.952 CRCGN009_HEPG2_24H:L08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.0138 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.83814 PMC3751638__F3 PFOCR Pathway Figure Associations 2023 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OC315 CCLE Cell Line Gene Expression Profiles -1.0 -2.40592 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neuronal cell body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.252 BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.02438 496100499_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.5978 A704 COSMIC Cell Line Gene Mutation Profiles 1.0 null Heart disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.03 regulation of cellular process GO Biological Process Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K42873980 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31565 Signal Transduction Reactome Pathways 2014 1.0 null BRD-K37803976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45054 BRD-K90548911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38378 GPCR ligand binding Reactome Pathways 2014 1.0 null A3-KAW COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN017_MCF10A.TP53.M_24H:H08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.37378 CRCGN014_HEPG2_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.12883 BRD-K94196749 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67137 BRD-K91506006 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.18074 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.935616 outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.824234 CRCGN014_HEPG2_24H:K13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.7311 BRD-K12313989 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18929 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.922971 membrane GO Cellular Component Annotations 2015 1.0 null BRD-K61053165 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24871 CRCGN013_HEPG2_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.0899 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.6008 CRCGN016_MCF10A.TP53.M_24H:F14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8518 Peptide ligand-binding receptors Reactome Pathways 2024 1.0 null CRCGN016_MCF10A.WT.HP_24H:F05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.91191 avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.735559 axon terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.174635 BRD-K43136464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03401 CRCGN012_HEPG2_24H:L03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.37445 BRD-K97569931 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30779 cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04934 HT-144 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 BRD-K12239796 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46337 MY-M12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.939 Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Reactome Pathways 2014 1.0 null Anterior lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.451 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K06956443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50143 HCC1428 CCLE Cell Line Gene CNV Profiles 1.0 1.61195 BRD-K17060750 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07137 MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5869 [125I]NPW-23 (human) Guide to Pharmacology Chemical Ligands of Receptors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K93339508 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76086 BRD-K50961262 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.92556 CRCGN016_MCF10A.TP53.M_24H:C18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.28152 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36074 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRCGN015_MCF10A_48H:J16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.3557 BRD-K72050003 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14452 CRCGN016_MCF10A.TP53.M_24H:E20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.21644 BRD-K13204142 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81333 CRCGN011_HEPG2_24H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.9627 adrenal GeneRIF Biological Term Annotations 1.0 null NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K57468571 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08312 CRCGN016_MCF10A.WT.HP_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.94797 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056959 GCM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4763 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XK-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN016_MCF10A.WT.HP_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.73065 CRCGN017_MCF10A.TP53.M_24H:L22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.41833 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4871-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SQ1 CCLE Cell Line Gene Expression Profiles 1.0 1.78311 SPI1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K86228587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35163 BRD-K86911380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22187 BRD-K11596967 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69656 NPB Guide to Pharmacology Protein Ligands of Receptors 1.0 null G alpha (i) signalling events Reactome Pathways 2014 1.0 null MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888412 Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K84478344 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00716 Amelogenesis imperfecta type 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 neuropeptide binding GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.323144 MDA MB435 BioGPS Cell Line Gene Expression Profiles 1.0 1.4988 binding GO Molecular Function Annotations 2015 1.0 null ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01549 BRD-K45833502 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.08118 ZIC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.8791 BRD-K03304013 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1572 BRD-K11577431 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.07497 NCI-H661 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K69854611 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.89042 BRD-K06431647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.0279 GSE193258,GSE193259_2_v_1_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null CRCGN015_HEPG2_48H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.86837 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61058 Leydig cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.422 CRCGN016_MCF10A.WT.HP_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.7633 BRD-K44797534 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85885 CRCGN015_HEPG2_48H:P04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.23646 supporting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213112 CRCGN012_HEPG2_24H:D09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.49697 BRD-K32522318 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04818 SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K32930844 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2825 NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6963 RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27629 496100343_TCx_possible Alzheimer's disease_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.54222 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49577 SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5026 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39097 tissues GeneRIF Biological Term Annotations 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.322 CRCGN017_MCF10A.WT.HP_24H:P19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3971 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.951 BRD-K67931592 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06421 Hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.018 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5711 CRCGN016_MCF10A.TP53.M_24H:P14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.91699 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04221 BRD-K20897375 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21003 amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.747927 KLE COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null precursor GeneRIF Biological Term Annotations 1.0 null cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07032 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900406 NPW Guide to Pharmacology Protein Ligands of Receptors 1.0 null EFM19 CCLE Cell Line Gene CNV Profiles 1.0 2.12369 BRD-K14309706 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.31659 Parathyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.373118 BRD-K75806288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1671 G protein-coupled opioid receptor activity GO Molecular Function Annotations 2023 1.0 null Amygdala BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.0771 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.874979 BRD-K18070214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88025 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100588_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18047 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.79042 Autosomal dominant disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.865 PK59 CCLE Cell Line Gene CNV Profiles 1.0 1.91838 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25009 BRD-K75657700 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39202 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5981 CRCGN011_HEPG2_24H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.2817 Peptic ulcer disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.764 BRD-K17840858 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75201 Li TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.372 Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.532 Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.9717 NCIH28 DepMap CRISPR Gene Dependency 1.0 2.85431 CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10299 Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN009_HEPG2_24H:I13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.00369 membrane LOCATE Curated Protein Localization Annotations 1.0 null BRD-K00909602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45706 CRCGN014_HEPG2_24H:F17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0555 BRD-K63626200 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.74594 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23138 median nucleus of thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.253248 Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.894922 BRD-K62800316 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00629 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60398 BRD-K71538933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38821 gyrus rectus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02221 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE193258,GSE193259_5_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5478 BRD-K53186055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15531 membrane part GO Cellular Component Annotations 2015 1.0 null CRCGN017_MCF10A.TP53.M_24H:N16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.77705 HDAC6 ENCODE Transcription Factor Targets 1.0 null CRCGN017_MCF10A.TP53.M_24H:K03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.57847 BRD-K28774883 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05896 NEUROPEPTIDE W-30 DGIdb Drug Targets 2026 1.0 5.2932 system GeneRIF Biological Term Annotations 1.0 null neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050825 CRCGN009_HEPG2_24H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.81102 496100473_TCx_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.66263 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24319 Median nucleus of thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.473 CFPAC-1 GDSC Cell Line Gene Expression Profiles -1.0 -1.45177 59M DepMap CRISPR Gene Dependency 1.0 2.11298 KYSE410 DepMap CRISPR Gene Dependency 1.0 2.75158 BRD-K91022335 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4436 molecular transducer activity GO Molecular Function Annotations 2015 1.0 null GSE219195_4_v_2_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null Inhibin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.664 SHSY5Y DepMap CRISPR Gene Dependency 1.0 2.48275 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055201 BRD-K26709432 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.56419 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.7225 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24716 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931488 BRD-K81001899 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34074 Counting factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.267 BRD-K74568352 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.29551 GMS-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN016_MCF10A.WT.HP_24H:P22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.32575 BRD-K60030763 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49649 SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.75339 ETV3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0306 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042095 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14338 biological regulation GO Biological Process Annotations 2015 1.0 null BRD-K01512588 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01121 BRD-K56034970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61396 Zona incerta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.503 Alevin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.524 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.44148 gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068454 SHSYSY-RA BioGPS Cell Line Gene Expression Profiles -1.0 -0.921595 H3K36me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K94506829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61262 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFE280 CCLE Cell Line Gene Expression Profiles -1.0 -1.80674 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K82432417 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.506 ARNT-22903824-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K45495792 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14002 BRD-K76706127 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.85795 BRD-K82785545 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.18385 GSE111247_14_v_10_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.635572 INS-1E cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.032 JIMT-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.354826 H4K20me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null interstitial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.229568 SP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18641 GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Adrenal cortex cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.309 CRCGN017_MCF10A.TP53.M_24H:N02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.4128 GPCR downstream signaling Reactome Pathways 2014 1.0 null CRCGN010_HEPG2_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2974 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077307 Metabolic disorders of biological oxidation enzymes Reactome Pathways 2014 1.0 null NCIH510 CCLE Cell Line Gene CNV Profiles -1.0 -1.77358 BRD-K22591777 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13853 Paraventricular nucleus of hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.273 CRCGN016_MCF10A.WT.HP_24H:O09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.04215 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.63029 NH12 DepMap CRISPR Gene Dependency 1.0 2.35384 CRCGN015_HEPG2_48H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.95877 Parathyroid hormone secreting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.807 intrinsic component of plasma membrane GO Cellular Component Annotations 2015 1.0 null BRD-K10398797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.78925 CRCGN015_MCF10A.WT.HP_24H:F16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.6003 FAM156B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02947 CRCGN015_MCF10A_48H:P04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.25705 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0251 SMC3 ENCODE Transcription Factor Targets 1.0 null Preoptic area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.345 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.4586 imatinib_homo sapiens_gpl96_gds3043 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K69521416 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42017 BRD-K85917058 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82742 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.33536 CRCGN015_HEPG2_48H:M16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.03759 CRCGN015_MCF10A_48H:G05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.0535 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K84517695 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21477 Abdominal obesity-metabolic syndrome 1 DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.865 TBK1_druginhibition_188_GSE53658 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.17285 Eating disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.276 BRD-K79067166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39372 sertoli cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23781 BRD-K27610371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17132 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.88087 MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7382 arsenic trioxide_homo sapiens_gpl201_gse48441 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K52956006 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35226 KYSE-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null la7 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.651 CRCGN015_HEPG2_48H:M17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.07364 PSN1 CCLE Cell Line Gene CNV Profiles 1.0 1.34279 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cell projection GO Cellular Component Annotations 2015 1.0 null BRD-K07390518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44039 BRD-K26074237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48677 BRD-K03886176 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63557 BRD-K10748141 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27884 CRCGN016_MCF10A.TP53.M_24H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.2682 A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.81638 BRD-K01787291 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.37955 CRCGN010_HEPG2_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.82429 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34258 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cell communication GO Biological Process Annotations 2015 1.0 null POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K41026056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.74369 BRD-K65888165 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26208 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRCGN015_MCF10A_48H:H22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.76033 FGFR1_knockdown_94_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.86065 MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1584 BRD-K61555339 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19181 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K75869095 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65282 GSE224096_1_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A6S3-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05898 SKG-IIIA COSMIC Cell Line Gene Mutation Profiles 1.0 null Neuropeptide B/W receptor family InterPro Predicted Protein Domain Annotations 1.0 null primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.60882 GSE153871_1_v_2_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K86050213 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16435 CRCGN013_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.19474 Adrenocortical carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.314 fasciculatareticularis GeneRIF Biological Term Annotations 1.0 null CRCGN016_MCF10A.TP53.M_24H:F11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.13902 cell-cell signaling GO Biological Process Annotations 2015 1.0 null H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K77820593 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12073 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24813 BRD-K90877053 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04169 BRD-K99116119 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33029 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null BRD-K51525251 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.9763 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K04272258 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08637 DAUDI CCLE Cell Line Gene Expression Profiles 1.0 2.0432 PMC3751638__F3 PFOCR Pathway Figure Associations 2024 1.0 null CRCGN015_MCF10A.TP53.M_24H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.6492 ERF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4003 female germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.445672 496100323_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.20795 BRD-K09337184 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.53923 BRD-K90460185 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75006 striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896051 GSE131660_2_v_0_piperlongumine_human RummaGEO Drug Perturbation Signatures -1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.957471 CRCGN011_HEPG2_24H:O03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.9681 Zona fasciculata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.51 SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.10424 Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K84391462 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25349 BRD-K95922469 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87177 CRCGN010_HEPG2_24H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4528 SW1116 DepMap CRISPR Gene Dependency 1.0 2.17373 SUM149PT DepMap CRISPR Gene Dependency 1.0 2.87187 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889643 MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.866138 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.5579 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K18313650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23445 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039567 BRD-K10820981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.78281 BRD-K96604397 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00717 FOXI1-33610681-GES1-HUMAN-GASTRIC-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30682 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.28504 CRCGN014_HEPG2_24H:H09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.2665 CRCGN011_HEPG2_24H:O04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.47005 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A.TP53.M_24H:B17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0427 posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.7647 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.931319 hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.253908 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.07527 NRARP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5292 cell part GO Cellular Component Annotations 2015 1.0 null Mesothelioma_MESO_TCGA-TS-A7OY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN013_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.1782 BRD-K33102216 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43894 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.886412 HS2ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69716 BRD-A69097282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.47001 BRD-K89837874 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08849 H4 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K50127933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24924 BRD-K18084996 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62153 GSE193258,GSE193259_2_v_0_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null Fetallung BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.55241 A-VN-1203-2004(H5N1)_Day7-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.55549 BRD-K17553044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05433 TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K80940089 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30256 Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.764 Adrenal cortex disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.225 Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RS11846 BioGPS Cell Line Gene Expression Profiles 1.0 2.41625 distribution GeneRIF Biological Term Annotations 1.0 null CRCGN015_MCF10A_48H:G01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.9642 CRCGN014_HEPG2_3H:N02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.40511 axon part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.059678 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25009 cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.438739 CRCGN013_HEPG2_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.42337 NCI-H2444 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900406 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9228 BRD-K86192746 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.088 CRCGN016_MCF10A.WT.HP_24H:M01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.23218 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null BRD-K17765399 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68576 Calvarium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.965 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.856115 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0341 HS936T CCLE Cell Line Gene Expression Profiles -1.0 -2.2351 CGTH-W-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K78866450 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59987 MYC ENCODE Transcription Factor Targets 1.0 null neurotransmitter receptor activity GO Molecular Function Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null AIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06675 stria terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.922055 KYSE520 DepMap CRISPR Gene Dependency 1.0 2.22412 253J CCLE Cell Line Gene Expression Profiles 1.0 1.65305 Parkin_OE_GDS4476_55_human_U87MG GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ZNF384_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04033 cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.847579 CRCGN009_HEPG2_24H:K13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.2289 PIANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17717 NEUROPEPTIDE W-23 DGIdb Drug Targets 2026 1.0 5.2932 LXF289 CCLE Cell Line Gene CNV Profiles -1.0 -1.49865 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63662 plicamycin LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.25811 cranium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.135274 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.28213 WSUDLCL2 CCLE Cell Line Gene Expression Profiles 1.0 2.86999 G protein-coupled receptor activity GO Molecular Function Annotations 2025 1.0 null Caudate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.897 MKN7 CCLE Cell Line Gene CNV Profiles 1.0 1.65626 BRD-K72194126 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.30415 BRD-K89324382 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.71837 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 CRCGN015_MCF10A.WT.HP_24H:H08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.16385 BRD-K14124956 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41636 SW13 COSMIC Cell Line Gene Mutation Profiles 1.0 null stomach GTEx Tissue Gene Expression Profiles -1.0 -1.36246 parolfactory gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13662 striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.947447 KYSE-520 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7498 A172 BioGPS Cell Line Gene Expression Profiles -1.0 -0.832269 BRD-K94442101 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20962 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5913 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.983 HTC-C3 GDSC Cell Line Gene Expression Profiles 1.0 1.41939 Intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.698 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTV1DM DepMap CRISPR Gene Dependency 1.0 3.80583 BRD-K74811560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.98319 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.057017 BRD-K70851916 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34951 SARS-CoV MA15_Day4-PFU-10^5_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.18768 CRCGN017_MCF10A.TP53.M_24H:K23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.2257 BRD-K01827055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54707 NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.20154 SPI1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K38345640 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18658 Phosphoglycerate kinase 1 deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.193 MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.02076 ACHN BioGPS Cell Line Gene Expression Profiles 1.0 0.910036 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84782 BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HT29 BioGPS Cell Line Gene Expression Profiles 1.0 1.58049 BRD-K27888332 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22509 BRD-A26343863 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06667 CRCGN016_MCF10A.TP53.M_24H:P20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.3457 BRD-K36726853 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10615 CRCGN015_MCF10A.TP53.M_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.0977 BFTC-905 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN015_HEPG2_48H:J17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.70906 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A818-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K21139023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04481 HOP92 BioGPS Cell Line Gene Expression Profiles -1.0 -0.988757 BRD-K39223744 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09311 Reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.179 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.37572 CRCGN008_HEPG2_24H:O06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.56745 neuropeptide signaling pathway GO Biological Process Annotations 2023 1.0 null TE8 DepMap CRISPR Gene Dependency 1.0 2.33954 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27741 NCIH520 CCLE Cell Line Gene Expression Profiles 1.0 1.35441 Autosomal genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.865 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.895642 LNZTA3WT4 DepMap CRISPR Gene Dependency 1.0 2.17195 BRD-K91268803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82971 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null g-protein coupled peptide receptor activity GO Molecular Function Annotations 2015 1.0 null BRD-K05357297 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01017 ZFP57 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.311 SNU1544 DepMap CRISPR Gene Dependency 1.0 6.43693 molecular_function GO Molecular Function Annotations 2015 1.0 null RPMI 8226 BioGPS Cell Line Gene Expression Profiles 1.0 0.871544 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SO-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10204296-13578_2023_1034_MOESM16_ESM.xlsx-Black-ZNF671_ZNF671 Rummagene Transcription Factor Associations 2026 1.0 null striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.96097 BRD-K54272776 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52229 BRD-K56373119 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09652 Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.1602 KP2 DepMap CRISPR Gene Dependency 1.0 2.8651 BRD-K52973286 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44343 LOXIMVI COSMIC Cell Line Gene Mutation Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0711 BRD-K46620987 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67983 HDAC1 ENCODE Transcription Factor Targets 1.0 null Hypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.685 Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K79829201 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2453 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH3255 CCLE Cell Line Gene Expression Profiles -1.0 -2.2139 CRCGN016_MCF10A.TP53.M_24H:L11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.41407 MXI1 ENCODE Transcription Factor Targets 1.0 null 18801183-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null H4K20me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TE8 CCLE Cell Line Gene CNV Profiles 1.0 1.50126 WM115 DepMap CRISPR Gene Dependency 1.0 4.00678 BRD-K86817746 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08189 SKNFI CCLE Cell Line Gene Expression Profiles 1.0 2.56822 Second instar larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.537 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K57228212 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18225 BRD-K17482709 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.33365 NVT complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.812 Peptide ligand-binding receptors Reactome Pathways 2014 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KT-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04261 BRD-K11672894 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04852 BRD-K87530935 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69892 MJ CCLE Cell Line Gene Expression Profiles 1.0 1.51526 GPCR downstream signalling Reactome Pathways 2024 1.0 null BRD-K52335877 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.99148 NB7 DepMap CRISPR Gene Dependency 1.0 2.51993 BRD-K07525144 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10843 BRD-K92432769 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.94212 SPI1 ChEA Transcription Factor Targets 1.0 null NB6 DepMap CRISPR Gene Dependency 1.0 2.96352 CRCGN016_MCF10A.TP53.M_24H:L10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.98949 CRCGN015_HEPG2_48H:C22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.8293 neuron projection terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.181524 CRCGN012_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.5161 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -1.36246 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.7953 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14727 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A6-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K84636055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46325 BRD-K05639803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.25829 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66197 BRD-K52731672 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.14795 UNC13B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74371 BRD-K38111331 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37097 outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07738 CRCGN017_MCF10A.TP53.M_24H:M04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.46156 BRD-K19474742 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09068 BRD-K08388529 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05007 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9933 Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K03554945 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35766 PHOX2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02817 Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Periventricular nucleus of hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.24 CRCGN015_HEPG2_48H:J16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.20095 BRD-K16852474 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.90014 Luteal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.87 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05089 Stria terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.537 LMAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57896 BRD-K80239721 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.78921 BRD-K00620786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.88282 BRD-K21635266 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69021 CRCGN014_HEPG2_3H:M21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.49245 H4K20me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Vomeronasal organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.584 CRCGN009_HEPG2_24H:F19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.81175 Cryptorchidism DisGeNET Gene-Disease Associations 1.0 null BRD-K90702609 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30068 ERG_01_17 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.89401 BRD-K25226763 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00972 BRD-K05846874 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.65366 IM9 DepMap CRISPR Gene Dependency 1.0 3.91924 Germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.88 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08536 OAW-28 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K59159023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60378 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4065 GSE190316,GSE190324_10_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07563 Zona glomerulosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.301 Signaling by GPCR Reactome Pathways 2024 1.0 null central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.947622 HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05218 Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null BRD-K10696228 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50436 BRD-K02681754 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36473 HSC3 CCLE Cell Line Gene Expression Profiles 1.0 1.51093 HS229T CCLE Cell Line Gene Expression Profiles -1.0 -1.71963 NCIH1836 DepMap CRISPR Gene Dependency 1.0 3.8964 CRCGN015_HEPG2_48H:E13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.5675 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42369 thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062134 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.5577 CRCGN010_HEPG2_24H:K13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.9034 SPI1_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K18307373 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01718 superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44853 FMN reductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.02 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null BRD-K97373334 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3175 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K55800245 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0443 BRD-K60052521 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55008 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.359664 middle frontal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17567 CBX8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO201 DepMap CRISPR Gene Dependency 1.0 3.05173 BRD-K15800236 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.91663 BRD-K78007953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22678 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.31676 SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.186 BRD-K64698045 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54075 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CRCGN016_MCF10A.WT.HP_24H:D04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.8777 opioid receptor activity GO Molecular Function Annotations 2015 1.0 null TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3676 COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45308 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K46269666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57087 BRD-K73462370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48145 BRD-K35588268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61676 CRCGN016_MCF10A.TP53.M_24H:K05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 10.0 PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3 Rummagene Transcription Factor Associations 2026 1.0 null SW620 BioGPS Cell Line Gene Expression Profiles 1.0 0.88638 BRD-K73357447 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70403 T3M4 BioGPS Cell Line Gene Expression Profiles 1.0 1.05963 BRD-K52152765 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09039 opioid receptor signaling pathway GO Biological Process Annotations 2015 1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null precentral gyrus, right, superior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00515 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Actomyosin contractile ring COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.84 PL45 CCLE Cell Line Gene Expression Profiles 1.0 1.99616 BRD-K84974041 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04084 cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946553 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10096 BRD-K78003637 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20941 CRCGN015_MCF10A.WT.HP_24H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.59156 BRD-K47541706 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22321 CRCGN017_MCF10A.WT.HP_24H:K22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.7851 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.98274 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.877429 G protein-coupled receptor homodimeric complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.058 Habenula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.851 RMGI DepMap CRISPR Gene Dependency 1.0 2.21496 Olfactory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.942 Nucleus preopticus lateralis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.881 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57601 Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K28351377 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37453 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuron projection GO Cellular Component Annotations 2023 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954758 Rapp-Hodgkin syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825145 BRD-K61363662 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.385 BRD-K43918582 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58696 BRD-K72146456 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.22532 BRD-K25954314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04695 Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955794 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.869688 Rectum adenocarcinoma_READ_TCGA-EI-6506-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.6514 Cryptorchidism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.535 CRCGN014_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.78195 ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00866 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.71418 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.893763 GSE193258,GSE193259_5_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null Germinal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.913 neuroactive ligand receptor interaction KEGG Pathways 1.0 null BRD-K17420784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59912 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5108-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K93023309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33387 H3K27me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARNT ChEA Transcription Factor Targets 1.0 null BRD-K68980973 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15752 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 SR786 CCLE Cell Line Gene CNV Profiles 1.0 1.59309 MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.8927 CRCGN015_HEPG2_48H:O10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.73178 BRD-K71414336 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7699 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17689 caudal subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.13449 UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.11958 BRD-K44298652 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00391 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.885479 CAOV-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 BRD-K30628727 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.25145 BRD-K87537204 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35804 CRCGN012_HEPG2_24H:M13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.59161 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.992326 CRCGN011_HEPG2_24H:L03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.9576 NCIH716 CCLE Cell Line Gene CNV Profiles 1.0 1.44339 Adrenocortical cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.693 E2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4332 orbital frontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24604 BRD-K31081052 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74031 Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 BRD-K07959057 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42142 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.90204 BRD-K50716325 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23162 CRCGN010_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.7663 BRD-K11054031 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44132 CHD1 ENCODE Transcription Factor Targets 1.0 null ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Tegmentum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.217 BRD-K64132098 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.88013 BRD-K81035073 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.18997 CRCGN008_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.1076 Labial palp TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.594 RARA_KD_GDS4065_42_human_MCF-7 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Abdominal obesity-metabolic syndrome DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.865 Habenular trigone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.71 SPI1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K48145537 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5987 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5581 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.466 BRD-K49529874 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0632 BRD-K43901257 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14912 EGR1 ChEA Transcription Factor Targets 1.0 null Class A/1 (Rhodopsin-like receptors) Reactome Pathways 2014 1.0 null BRD-K48171978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.68491 BRD-K56699877 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56342 CRCGN012_HEPG2_24H:O04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.66854 mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38697 BRD-K04367224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17947 Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.03 Tectum mesencephali TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86 CRCGN013_HEPG2_24H:O06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8327 l45 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.029 BRD-K52202153 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16425 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K95218317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87663 BRD-K58300049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21206 Fallopian Tube GTEx Tissue Gene Expression Profiles 2023 1.0 2.6079 CLDN1_OE_GDS3510_31_human_CL1-5 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KO52 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN013_HEPG2_24H:O05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.84058 COLO-783 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN015_HEPG2_48H:B11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.79279 CRCGN015_HEPG2_48H:D17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.72349 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4976-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40814 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-01A-21R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KPNYS DepMap CRISPR Gene Dependency 1.0 4.02162 BRD-K93176491 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.70816 BRD-K98953346 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4982 BRD-K57262525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16765 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.903107 Monogenic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.865 characterization GeneRIF Biological Term Annotations 1.0 null Restless legs syndrome DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.951 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.369747 RH30 CCLE Cell Line Gene CNV Profiles -1.0 -1.42131 Agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 BRD-K56776985 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26273 BRD-K99119142 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11172 BRD-K98510376 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17145 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K77032979 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79835 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN015_MCF10A.TP53.M_24H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.521 primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03206 PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K09819684 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04026 BRD-K02839126 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3869 BRD-K51054234 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28954 BRD-K90644597 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77757 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24195 membrane LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K37929710 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58203 BRD-K73994499 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.91425 Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cryptorchidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.50623 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K11113009 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43744 paracentral lobule, anterior part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.826137 HS766T CCLE Cell Line Gene CNV Profiles 1.0 2.00555 SW1417 CCLE Cell Line Gene CNV Profiles 1.0 1.49225 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.787092 ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0911 CRCGN012_HEPG2_24H:K01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.2796 Lateral habenular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.621 CRCGN016_MCF10A.WT.HP_24H:N15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.61465 0317956-0000-3774 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K96567801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02106 UACC893 CCLE Cell Line Gene CNV Profiles 1.0 1.40731 HEL9217 CCLE Cell Line Gene CNV Profiles -1.0 -1.71022 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.15776 neuropeptide signaling pathway GO Biological Process Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16549 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.141343 H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K66841501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58761 BRD-K75426080 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39224 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03608 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.098007 INSM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0417 PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON Rummagene Transcription Factor Associations 2026 1.0 null KDM2B-26808549-CHIP-SEQ-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K79me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K90741031 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42812 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02562 sulfamethoxazole-2296 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K90103010 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26326 SK-MES-1 GDSC Cell Line Gene Expression Profiles 1.0 1.67021 BRD-K56716645 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46435 germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.438542 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K96623405 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.22717 BHLHE40 ENCODE Transcription Factor Targets 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles -1.0 -3.02596 AHR ChEA Transcription Factor Targets 1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05131 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.961328 BRD-K58491882 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27022 BRD-K73475697 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1015 Signal Transduction Reactome Pathways 2024 1.0 null CEMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6056 BRD-K47555438 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.6642 BRD-K09972656 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14552 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54592 signaling receptor activity GO Molecular Function Annotations 2015 1.0 null head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.372369 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.245 C99 DepMap CRISPR Gene Dependency 1.0 4.90618 CRCGN011_HEPG2_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.4862 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.29278 GPCRs, Class A Rhodopsin-like(Homo sapiens) WikiPathways Pathways 2014 1.0 null BRD-K50721666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75666 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K05940224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04379 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN016_MCF10A.TP53.M_24H:P24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.30555 ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.6793 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39305 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null clidinium LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28478 primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61883 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K27991961 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16422 CRCGN011_HEPG2_24H:O02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.9222 SPI1 ENCODE Transcription Factor Targets 1.0 null NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.0641 BRD-K63145472 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06868 Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.351 CRCGN015_HEPG2_48H:F16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.3073 BRD-K28916436 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29292 BRD-A08820802 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4739 MYC_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052514 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OCUM1 CCLE Cell Line Gene Expression Profiles 1.0 1.84965 neuropeptide binding GO Molecular Function Annotations 2023 1.0 null A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.55834 BRD-K58270905 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15338 BRD-K57498440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35141 BRD-K94088431 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81384 BRD-K85401814 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49084 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 HCC1187 CCLE Cell Line Gene CNV Profiles -1.0 -1.41805 BRD-K29039402 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.78018 CRCGN008_HEPG2_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.5898 cell part LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82448 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06068 H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K10638173 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24946 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.099762 BRD-K66253165 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.1188 CRCGN017_MCF10A.TP53.M_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.64052 BRD-K06958718 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20364 BRD-K01894374 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48315 HES7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1575 PMC9170129__F10 PFOCR Pathway Figure Associations 2024 1.0 null MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.94359 TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1716 precuneus, right, superior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.954733 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09321 neuron part GO Cellular Component Annotations 2015 1.0 null BRD-K64353626 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12004 BRD-K58779593 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50438 basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.439507 EP300 ENCODE Transcription Factor Targets 1.0 null GSE163275_1_v_0_irf8_human RummaGEO Gene Perturbation Signatures 1.0 null primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.906474 BRD-K29519734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15188 temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0899 CRCGN017_MCF10A.WT.HP_24H:E04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.53712 IZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08952 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amide binding GO Molecular Function Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7086-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN011_HEPG2_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2022 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.056642 lingual gyrus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28252 BRD-K44643967 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77508 CRCGN014_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.967 BRD-K21284411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0387 UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K35639494 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03355 Gastric antrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.235 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.83228 G-protein beta/gamma-subunit complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.834 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01549 outer SZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06795 BRD-A16760970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36388 seminiferous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.601283 CL-34 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.913942 single-organism cellular process GO Biological Process Annotations 2015 1.0 null ROS50 DepMap CRISPR Gene Dependency 1.0 5.13277 CRCGN015_HEPG2_48H:J22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.02545 BRD-K98637033 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7665 GSE193258,GSE193259_2_v_8_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K69879051 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34039 Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.951 superior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33692 EBC1 DepMap CRISPR Gene Dependency 1.0 3.58748 Optic lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.148 BRD-K73792260 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32652 PPARD ChEA Transcription Factor Targets 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02267 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.529826 BRD-K01793276 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17875 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04961 BRD-K32444429 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61832 HL60 BioGPS Cell Line Gene Expression Profiles -1.0 -1.97664 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN014_HEPG2_24H:D01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.86276 Fibrochondrogenesis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.472 496100492_TCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19573 BRD-K53257307 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54862 CRCGN012_HEPG2_24H:G05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.07536 RERFLCAD2 CCLE Cell Line Gene Expression Profiles -1.0 -1.67284 CRCGN012_HEPG2_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.51701 NCIH1385 CCLE Cell Line Gene Expression Profiles -1.0 -1.50159 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61222 CAL12T CCLE Cell Line Gene Expression Profiles -1.0 -1.45288 PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX1-sequence_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_HEPG2_48H:P06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.27337 signal transducer activity GO Molecular Function Annotations 2015 1.0 null BRD-K85567359 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57936 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 BRD-K28545166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52626 BRD-K73874262 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.8524 Fissured tongue DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K36393312 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08656 496100449_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.21527 BRD-K46623934 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.28814 SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.683 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21132 H2AFZ ENCODE Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.21006 SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.54325 BRD-K28853245 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15281 NCIH2023 CCLE Cell Line Gene Expression Profiles -1.0 -2.28745 BRD-K60918542 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56669 CRCGN009_HEPG2_24H:D11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.1468 BRD-K58333451 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64753 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50512 SkeletalMuscle BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.844118 H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K47410882 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37378 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.48373 paraventricular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.254239 BRD-K03765511 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23188 MAN1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82251 hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.764882 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.923056 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.848902 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.01229 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN009_HEPG2_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.84065 temporal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.26009 CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K01995700 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.7108 JHUEM1 DepMap CRISPR Gene Dependency 1.0 2.45168 dorsolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.901533 neuron projection GO Cellular Component Annotations 2015 1.0 null AHR-22903824-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K35441510 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1876 BRD-K40143134 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03804 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.523588 CRCGN015_HEPG2_48H:G05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.36693 Disorder of sexual development DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.303 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00836 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AGS DepMap CRISPR Gene Dependency 1.0 2.13834 AHR-22903824-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CRCGN009_HEPG2_24H:K01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.15138 SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null seminiferous tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.187722 PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_HEPG2_48H:G06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.84875 NCIH1373 CCLE Cell Line Gene CNV Profiles -1.0 -1.35767 proteincoupled GeneRIF Biological Term Annotations 1.0 null Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 BRD-A30962679 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.04491 BRD-K26543702 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01981 Pain agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 DIDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77842 CP67-MEL GDSC Cell Line Gene Expression Profiles -1.0 -1.47489 ABL1_knockdown_137_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.57606 BRD-K87277021 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15583 BRD-K22564762 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17043 HSF1_KD_GDS1733_752_human_HeLa cells - 2 Hour by siHSF1_1 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K01951210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18327 ELF1 ENCODE Transcription Factor Targets 1.0 null MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes_Muscle - Striated (Skeletal) (MMHCC)_GSE1462 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.7361 CRCGN009_HEPG2_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.16367 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19611 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68014 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.30123 BRD-K24076516 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60847 BRD-K38118226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.51007 Body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.509691 CRCGN012_HEPG2_24H:G07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4661 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31771 CRCGN011_HEPG2_24H:O06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.91895 germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236332 BRD-K27823380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16181 Olfactory tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.74 BRD-K16468319 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51425 NCIH854 CCLE Cell Line Gene CNV Profiles 1.0 1.63139 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K76175734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09548 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K21467089 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09518 family GeneRIF Biological Term Annotations 1.0 null BRD-K66865641 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.03366 BRD-K73227372 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79525 PAK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13253 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NFYB_01_238 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.81737 BRD-K38035271 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50352 Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null SNU308 CCLE Cell Line Gene CNV Profiles -1.0 -1.70866 BRD-K39206254 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06843 SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.900254 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Anal fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.228 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.868227 BRD-K05090634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44285 CRCGN014_HEPG2_24H:G24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.02396 plasma membrane GO Cellular Component Annotations 2015 1.0 null CRCGN017_MCF10A.TP53.M_24H:O21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.37574 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.919375 BRD-K11247495 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11933 G cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.115 BRD-K03221986 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.50199 CRCGN014_HEPG2_24H:D13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.96576 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25009 single-organism process GO Biological Process Annotations 2015 1.0 null BRD-K83815065 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5627 transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null BRD-K74789550 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07039 NCI-H1688 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null IALM CCLE Cell Line Gene Expression Profiles 1.0 1.72347 BRD-K74677971 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29591 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CRCGN017_MCF10A.TP53.M_24H:I10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.53856 anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54277 H2AK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CRCGN015_HEPG2_48H:G01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.7623 angular gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.51239 ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NMCG1 CCLE Cell Line Gene Expression Profiles -1.0 -2.11184 BRD-K15930345 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33048 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12591 NEUROPEPTIDE B-29 DGIdb Drug Targets 2026 1.0 5.2932 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.899211 CRCGN014_HEPG2_24H:F03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.53845 BRD-K89232006 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60202 Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Asthma_Epithelial Cell_GSE4302 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.4829 BRD-K22534934 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55578 BRD-K96713984 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30648 BRD-K13781734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05391 BRD-K97263385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10906 BRD-K54939987 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0191 BRD-K56950366 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52623 Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K09960817 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67559 BRD-K29936219 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43609 CRCGN014_HEPG2_24H:F21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.78805 GRM CCLE Cell Line Gene Expression Profiles -1.0 -1.56295 CRCGN017_MCF10A.WT.HP_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.72215 basal nucleus of meynert, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32592 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K88344082 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09762 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049485 BRD-K59667434 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49326 CRCGN014_HEPG2_3H:H09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.5016 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31183 CRCGN015_MCF10A.WT.HP_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.76415 BRD-K72721410 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43116 HUH1 CCLE Cell Line Gene Expression Profiles 1.0 1.60831 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.966368 BRD-K99048639 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1523 CRCGN009_HEPG2_24H:O19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.9117 RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04996 496100394_TCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19898 BRD-K57830670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.77898 Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K19536737 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75113 BRD-K19734887 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.268 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.953813 testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.136965 BRD-A20242387 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45265 BRD-K27137352 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0943 BRD-K68836091 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33413 Interstitial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.25 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65491 GSE193258,GSE193259_5_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null CRCGN016_MCF10A.TP53.M_24H:O20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.11531 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.409351 PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null substantia innominata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30591 BRD-K36156445 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34316 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7886-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3348545-NIHMS263168-supplement-3.pdf-15-ZGPAT_ZGPAT Rummagene Transcription Factor Associations 2026 1.0 null primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.719 BRD-K46126513 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62567 BRD-K26708780 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40796 BRD-K11093795 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09356 Paraventricular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.475 KURAMOCHI COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH1793 DepMap CRISPR Gene Dependency 1.0 4.29762 Duodenal ulcer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.764 CRCGN013_HEPG2_24H:O02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.16827 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.12757 Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K86722849 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4965 CRCGN013_HEPG2_24H:K13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.99212 Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 Spore wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.184 outer CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21292 g-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO Biological Process Annotations 2015 1.0 null BRD-K87053028 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1046 Cornelia de Lange syndrome 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.289 BRD-K13844473 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18038 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7502 cerebral gray matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236332 A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.91115 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.82734 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN016_MCF10A.WT.HP_24H:D07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.2374 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.97881 craniofacial region TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.124007 H3K27me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K94580242 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56378 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.34963 BRD-K60948317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32006 Supraoptic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.056 CRCGN015_MCF10A.TP53.M_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4091 CRCGN013_HEPG2_24H:B07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.59012 CRCGN016_MCF10A.WT.HP_24H:N14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.3872 fusiform gyrus, left, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00189 BRD-K91490997 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15273 NCIH82 DepMap CRISPR Gene Dependency 1.0 2.04788 BRD-K19139070 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25724 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.276145 Neuropeptide B/W receptor 2 InterPro Predicted Protein Domain Annotations 1.0 null H3K4ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CRCGN015_MCF10A_48H:O11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.4052 BRD-K77591784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.39118 Cell septum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.542 BRD-K45909830 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.9246 integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.26385 CRCGN009_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.94792 SPI1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE221577_1_v_0_pik3r1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE129241_1_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.319328 gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.128455 BRD-K65107903 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.79994 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.00448 BRD-K21483524 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.12238 BRD-K27885385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12014 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041611 639-V GDSC Cell Line Gene Expression Profiles -1.0 -1.49512 BRD-A71962374 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06703 BRD-K47707657 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.10808 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10875 BRD-K29331543 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62675 BRD-K62226454 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01706 CHL1 CCLE Cell Line Gene CNV Profiles -1.0 -2.14613 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.76278 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NPB Pathway Commons Protein-Protein Interactions 1.0 null OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09624 CRCGN017_MCF10A.TP53.M_24H:K20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.9938 A-VN-1203-2004(H5N1)_Day4-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.55812 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null RBE DepMap CRISPR Gene Dependency 1.0 2.79312 CRCGN013_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.96465 CRCGN017_MCF10A.TP53.M_24H:G11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.33826 BRD-K31010207 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.4424 CRCGN009_HEPG2_24H:O04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.20382 Suprachiasmatic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.923 Neuroactive ligand-receptor interaction KEGG Pathways 2026 1.0 null PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_HEPG2_48H:P05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.51986 BRD-K53617314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57854 NCIH647 CCLE Cell Line Gene CNV Profiles 1.0 1.56138 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38921 HT144 CCLE Cell Line Gene CNV Profiles 1.0 1.64208 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BK-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K91467755 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45985 Cell body fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.512 JEG3 DepMap CRISPR Gene Dependency 1.0 4.55269 subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.95991 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K55835264 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33978 HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.63183 CRCGN008_HEPG2_24H:G24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.4534 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.88995 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04785 CRCGN011_HEPG2_24H:L12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.2818 CRCGN016_MCF10A.WT.HP_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.67397 posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39164 CHD2 ENCODE Transcription Factor Targets 1.0 null GSE145249_0_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null CRCGN015_MCF10A_48H:P06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.60149 BRD-K09863466 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30611 CRCGN013_HEPG2_24H:K01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.44045 CRCGN016_MCF10A.WT.HP_24H:K20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2556 spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065273 BCAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27404 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K11227160 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58831 ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954758 SNU8 DepMap CRISPR Gene Dependency 1.0 2.11455 H3K36me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COLO775 CCLE Cell Line Gene CNV Profiles -1.0 -1.49142 SU-DHL-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null imatinib_homo sapiens_gpl96_gds3044 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K13888422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.04043 BRD-K25982056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15093 CAL29 CCLE Cell Line Gene CNV Profiles 1.0 1.42689 496100292_PCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12937 cingulate gyrus, parietal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18329 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K01980291 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87931 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -2.38974 CRCGN015_HEPG2_48H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.36636 outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26641 MCF7 CCLE Cell Line Gene CNV Profiles 1.0 1.64208 BRD-K09521953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44655 CRCGN009_HEPG2_24H:O06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.50101 CRCGN014_HEPG2_24H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.27165 BRD-K94476572 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1943 MAFK ENCODE Transcription Factor Targets 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.993982 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066753 BRD-K22957824 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03412 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.865 CRCGN015_HEPG2_48H:G13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.58039 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55481 BRD-K98117883 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.43368 NB13 DepMap CRISPR Gene Dependency 1.0 8.20759 BRD-K64451058 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02411 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null BRD-A14803952 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19796 PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K50623282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01728 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43166 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48206 Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE1 CCLE Cell Line Gene CNV Profiles 1.0 1.38914 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.930682 midbrain central gray TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.579617 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.129872 BRD-K98731550 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00243 Adrenal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.603 BRD-K15690866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02318 BRD-K80921954 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61051 BRD-K75440064 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67014 BRD-K25236390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33329 planum polare, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01611 NCVADR RES BioGPS Cell Line Gene Expression Profiles -1.0 -0.921595 BRD-K40745976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08267 EFO-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852879 HCC1419 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 BRD-K97949309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.96693 BRD-K59587063 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27206 Brain Lower Grade Glioma_LGG_TCGA-HT-7467-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRCGN011_HEPG2_24H:C24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.216 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.988987 KINGS1 DepMap CRISPR Gene Dependency 1.0 2.78334 BRD-K46715415 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.07304 ZSCAN31 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.6948 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059973 NCIH1666 CCLE Cell Line Gene Expression Profiles -1.0 -1.49349 Acute Myeloid Leukemia_LAML_TCGA-AB-2865-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G alpha (i) signalling events Reactome Pathways 2024 1.0 null ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.847 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.83336 spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.319328 BICR56 DepMap CRISPR Gene Dependency 1.0 2.07702 CRCGN017_MCF10A.TP53.M_24H:P24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.93288 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45308 Oliva TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.13 plant-type cell wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.185 Adrenal gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 CRCGN015_HEPG2_48H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.09161 Avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.439 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GS-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IL-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04128 MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K84062787 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.25189 GSE85880,GSE85881_4_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null plasma membrane part GO Cellular Component Annotations 2015 1.0 null SW1463 DepMap CRISPR Gene Dependency 1.0 2.79621 BRD-K48528697 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01123 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07405 CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.56808 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058514 CRCGN017_MCF10A.WT.HP_24H:N09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.57195 AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.898073 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069168 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056285 BRD-K55505527 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12631 CRCGN015_MCF10A_48H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.34636 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43166 CRCGN009_HEPG2_24H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.32784 H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K76755163 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18213 BRD-K28140275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00948 BRD-K23440419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.92372 Medulla oblongata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.435 CRCGN015_HEPG2_48H:K09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.10317 BRD-K90806964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.74952 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.830936 A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888412 BRD-K98601267 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28548 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75712 Root hair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.916 Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.08678 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.28213 BRD-K87602457 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21361 posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.41376 Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.52082 HDAC2 ENCODE Transcription Factor Targets 1.0 null germinal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.445672 Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN011_HEPG2_24H:M13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8011 JIMT1 CCLE Cell Line Gene CNV Profiles 1.0 1.50658 BRD-K18562847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64035 NEUROPEPTIDE B-23 DGIdb Drug Targets 2026 1.0 10.5864 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28569 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.891586 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12604 BRD-K82504878 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.63151 HCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.97284 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49945 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K07460436 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34292 Corpus luteum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.883 brain GTEx Tissue Gene Expression Profiles 1.0 1.19091 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852879 BRD-K34445094 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.60061 MAFF ENCODE Transcription Factor Targets 1.0 null CRCGN011_HEPG2_24H:D11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.0113 BRD-K92767663 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15493 BRD-K10459972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25431 BRD-K46641047 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53671 pioglitazone_mus musculus_gpl2897_gse8806 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CRCGN014_HEPG2_3H:N09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.7746 BRD-K83684822 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01178 HKA1 DepMap CRISPR Gene Dependency 1.0 3.83802 Anorexia nervosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.382 temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.481259 BRD-K52657580 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06098 BRD-K02329600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85322 496100327_PCx_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.81114 WM2664 CCLE Cell Line Gene Expression Profiles -1.0 -1.59871 signal transduction GO Biological Process Annotations 2015 1.0 null BRD-K81779733 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80161 CRCGN015_HEPG2_48H:J23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.17587 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83172 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34905 CRCGN016_MCF10A.WT.HP_24H:O24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.10373 HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00289 G protein-coupled opioid receptor activity GO Molecular Function Annotations 2025 1.0 null SF295 GDSC Cell Line Gene Expression Profiles -1.0 -1.71389 ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0487 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Medication use (agents acting on the renin-angiotensin system) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.03979 BRD-K90230495 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16304 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051945 BACH1 ENCODE Transcription Factor Targets 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null leydig cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.321685 Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.358 BRD-A68842442 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72361 OVCAR3 BioGPS Cell Line Gene Expression Profiles 1.0 1.17262 CRCGN010_HEPG2_24H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4882 GDAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66327 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00878 SKN COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 Cerebrospinal AB1-42 levels in normal cognition GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.652288 short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.828513 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81W-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.882207 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28655 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34897 BRD-K15647573 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41053 KDM5A ENCODE Transcription Factor Targets 1.0 null CRCGN016_MCF10A.TP53.M_24H:H08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.2269 BRD-K62102480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17498 BRD-K44921931 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22388 BRD-K18887540 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27521 mammary gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.097435 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null Amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.452 IGROV1 CCLE Cell Line Gene Expression Profiles 1.0 1.64998 CRCGN017_MCF10A.WT.HP_24H:O19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.437 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.78512 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85477 cellular_component GO Cellular Component Annotations 2015 1.0 null Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.262 BRD-K96389533 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52066 GSE216273,GSE216292_0_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null neuropeptide signaling pathway GO Biological Process Annotations 2025 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25009 GSE193258,GSE193259_9_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25009 JVM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.64363 CRCGN017_MCF10A.TP53.M_24H:H07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.5116 BRD-K71563254 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26201 BRD-K57650037 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.32544 Corticotropic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.977 POLR2A ENCODE Transcription Factor Targets 1.0 null Syndrome DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.865 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54018 ligands GeneRIF Biological Term Annotations 1.0 null CD19+_BCells(neg._sel.) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.42638 nipple TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.719524 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09485 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.74036 BRD-K86371068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17075 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09018 BRD-K83966071 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53426 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.68577 CCRF-CEM COSMIC Cell Line Gene Mutation Profiles 1.0 null g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.369 MC116 CCLE Cell Line Gene Expression Profiles 1.0 2.51388 CRCGN008_HEPG2_24H:G17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.36515 BRD-K33597325 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33208 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.86376 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975607 Antral mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.095 CRCGN015_MCF10A.TP53.M_24H:K11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.25965 CRCGN014_HEPG2_24H:P01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.25971 EKVX COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K89638177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06209 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null BRD-K54478142 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30663 Hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.458 G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null Breast Cancer_Mammary Gland Tissue_GSE3744 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.78699 BRD-K99416393 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07699 H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.984543 KMS21BM CCLE Cell Line Gene CNV Profiles -1.0 -2.57442 Signaling by GPCR Reactome Pathways 2014 1.0 null HES2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4429 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42438 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.86587 NCIH446 DepMap CRISPR Gene Dependency 1.0 2.27442 CRCGN010_HEPG2_24H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.40264 PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3 Rummagene Transcription Factor Associations 2026 1.0 null NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.99625 CRCGN015_HEPG2_48H:L01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.74071 BRD-K13317726 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36372 CRCGN015_HEPG2_48H:F01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.6345 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.59603 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3955 Skin - Not Sun Exposed (Suprapubic) GTEx Tissue Gene Expression Profiles 2023 1.0 5.81214 Melanophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.839 BRD-K75584297 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08862 CRCGN015_MCF10A.WT.HP_24H:M16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.4484 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14056 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.814214 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.130443 HCC70 CCLE Cell Line Gene Expression Profiles -1.0 -1.97071 CRCGN015_MCF10A_48H:P13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.18402 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDK2_knockdown_132_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.3883 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFE-296 GDSC Cell Line Gene Expression Profiles -1.0 -1.97681 BRD-K18178356 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67429 BRD-A63503250 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21796 CTCFL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.8371 BRD-K68470956 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.07507 HMCB CCLE Cell Line Gene CNV Profiles -1.0 -1.97126 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null BRD-K74198088 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32125 CRCGN015_HEPG2_48H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.73962 neuropeptide receptor activity GO Molecular Function Annotations 2015 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871059 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.11886 Dorsal raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.392 BRD-K53224741 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.58644 BRD-K72842159 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1532 HCaRG_OE_GDS2426_711_human_HEK293 kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.70276 BRD-K19712135 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06997 neuron projection GO Cellular Component Annotations 2025 1.0 null Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.343 CRCGN015_HEPG2_48H:H01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.92638 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11975 CRCGN014_HEPG2_24H:B08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.1782 BRD-K75007044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.95322 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9979 SNU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04413 BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 JHH7 CCLE Cell Line Gene Expression Profiles 1.0 1.8002 CRCGN009_HEPG2_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.19498 BRD-K55852567 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18516 Central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.951 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16494 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 Subfornical organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.124 PHF8 ENCODE Transcription Factor Targets 1.0 null BRD-K24170552 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6264 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27915 BRD-K23118252 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00155 BRD-K11573765 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39395 BRD-K89260735 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15152 peptide binding GO Molecular Function Annotations 2015 1.0 null zona GeneRIF Biological Term Annotations 1.0 null Arcuate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.108 AN3CA CCLE Cell Line Gene Expression Profiles 1.0 1.67195 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03185 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19543 BRD-K73524144 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.10569 BRD-K64767126 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6258 single organism signaling GO Biological Process Annotations 2015 1.0 null peptides GeneRIF Biological Term Annotations 1.0 null BRD-K33637419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3091 CRCGN014_HEPG2_3H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4485 IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68811 Female germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.913 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21377 BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1336 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.38447 BRD-K57643011 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24513 peptide receptor activity GO Molecular Function Annotations 2015 1.0 null BRD-K42976515 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77978 CRCGN013_HEPG2_24H:J04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.02087 UACC-62 GDSC Cell Line Gene Expression Profiles -1.0 -1.61238 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.936225 central GeneRIF Biological Term Annotations 1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25009 BRD-K56283394 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23537 ZBTB7A ENCODE Transcription Factor Targets 1.0 null NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33665 HCC1419 DepMap CRISPR Gene Dependency 1.0 9.34282 BRD-K23203419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31017 W chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.546 PAX5 ENCODE Transcription Factor Targets 1.0 null cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2561 BRD-K21081985 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00786 BRD-K76691746 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72397 U20S BioGPS Cell Line Gene Expression Profiles -1.0 -1.45292 Adrenal gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.268 JMSU1 DepMap CRISPR Gene Dependency 1.0 2.20233 BRD-K89089981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1999 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -2.35612 496100404_PCx_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.22651 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37401 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45308 BRD-K88720906 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38994 A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.02888 BRD-K45893504 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.13513 NCI-H295 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.665 Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28479 NR1H4::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9437 Class A/1 (Rhodopsin-like receptors) Reactome Pathways 2024 1.0 null BRD-K32918816 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03233 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06196 BRD-K69074358 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35242 SKUT1 CCLE Cell Line Gene Expression Profiles 1.0 1.90673 BRD-K24514314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19075 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15428 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.8555 MZ in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.918652 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1584 COLO679 DepMap CRISPR Gene Dependency 1.0 6.17517 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.13864 BRD-K26063034 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.56816 BRD-K91895574 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.97639 BRD-K58028568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73146 GSE142210_11_v_8_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32218 CTCF ENCODE Transcription Factor Targets 1.0 null CRCGN011_HEPG2_24H:A09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.1692 Neuron projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855685 TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ARNT-22903824-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K43306617 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12156 amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844641 BRD-K66623602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11344 Midbrain central gray TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.456 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055751 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 integral component of plasma membrane GO Cellular Component Annotations 2015 1.0 null physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.89541 precentral gyrus, right, bank of the central sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30671 BRD-K41604824 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.88327 BRD-K51787437 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48623 P30-OHK GDSC Cell Line Gene Expression Profiles -1.0 -2.12722 BRD-A77164655 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60986 Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RDES CCLE Cell Line Gene Expression Profiles 1.0 1.5576 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38455 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65719 BRD-K06058625 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38025 G protein-coupled receptor activity GO Molecular Function Annotations 2023 1.0 null 786O CCLE Cell Line Gene Expression Profiles 1.0 1.36117 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0451 ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45806 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908156 BRD-K96239538 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.78776 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K48691065 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55127 CRCGN009_HEPG2_24H:L13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 10.0 CRCGN015_HEPG2_48H:G04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.59134 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7093 Disease Reactome Pathways 2014 1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17689 CRCGN011_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.4122 BRD-K13646706 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3397 Antropyloric mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.09 PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02807 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1168 Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.692493 BRD-K90255725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13936 CRCGN015_HEPG2_48H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.27832 endogenous GeneRIF Biological Term Annotations 1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K80945184 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21419 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.827735 BRD-K56591923 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.71127 CRCGN012_HEPG2_24H:I13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.03314 BRD-K84143716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66339 BRD-K72636868 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17904 CRCGN014_HEPG2_24H:D11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.7827 KRAS.PROSTATE_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null ELK3-25401928-HUVEC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZY-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K57724549 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3279 CRCGN016_MCF10A.TP53.M_24H:F05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.6027 BRD-K01360791 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.15072 TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.35456 nervous GeneRIF Biological Term Annotations 1.0 null CRCGN008_HEPG2_24H:G16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.5621 HS695T CCLE Cell Line Gene CNV Profiles 1.0 1.48161 8-MG-BA COSMIC Cell Line Gene Mutation Profiles 1.0 null KKU100 DepMap CRISPR Gene Dependency 1.0 3.12526 CRCGN009_HEPG2_24H:O05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.389 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8248 posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.848378 temporal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1308 BRD-K74056311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81093 hippocampus (hippocampal formation)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.9255 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43339 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YH-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K36099605 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69367 GSE145249_0_v_2_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K73479560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08905 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE193258,GSE193259_2_v_3_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-A82976259 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.9892 BRD-K09468701 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.8233 CHML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37986 UMUC14 DepMap CRISPR Gene Dependency 1.0 2.13582 SUIT2 DepMap CRISPR Gene Dependency 1.0 2.67178 UPCISCC152 DepMap CRISPR Gene Dependency 1.0 2.68933 superior parietal lobule, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.8706 [125I]NPW-23 (HUMAN) DGIdb Drug Targets 2026 1.0 5.2932 BRD-K23694339 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08911 intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.108067 CRCGN015_HEPG2_48H:K08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.76058 CRCGN010_HEPG2_24H:G16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.37155 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43273 SPI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH520 CCLE Cell Line Gene CNV Profiles -1.0 -1.41705 CRCGN012_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.9849 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.94331 k1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.816 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39172 Ventromedial hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.362 CRCGN011_HEPG2_24H:O05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.86615 BRD-K80724972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53129 RKN CCLE Cell Line Gene CNV Profiles 1.0 1.35397 PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX2-sequence_name_MSX2 Rummagene Transcription Factor Associations 2026 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 CRCGN014_HEPG2_24H:L18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.48594 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61218 breast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065685 NB10 GDSC Cell Line Gene Expression Profiles 1.0 1.52056 BRD-K66912462 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48233 Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K93223696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23578 BRD-K06403738 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00453 BRD-K32760954 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01899 BRD-K51779559 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01438 BRD-K13076765 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1917