association	dataset	threshold value	standardized value
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTPase activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
KIF18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3615
CCP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44553
GSE210662_2_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20818
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47204
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arthrogryposis multiplex congenita-3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18596
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135350_3_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119345_2_v_4_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110580_1_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11621
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03473
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4697
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.138
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02195
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424909
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6548
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98652
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60097
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERRFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33874
Papillary renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
TPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01048
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254112
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7363
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8556
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.888
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1099
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01357
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4396
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12914
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9564
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7295
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.346047
GA-04-SF76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225251
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05393
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.711
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3204
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28441
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01718
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00657
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2878
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01611
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0853
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02715
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5315
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368615
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5632
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.49763
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65437
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33929
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2696
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8530322-pone.0258316.s002.xlsx-GG_778_TH17-AA_778_TH17-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00749
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9821
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4018
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1413
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.383466
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7272
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63007
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0541
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4974
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25131
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33102
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.401227
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8963
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.472645
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7565
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6564
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.707
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66198
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18827
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8174
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.242
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6323
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28716
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01561
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233891
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5071
TAF6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35059
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347594
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
PMC11821528-41588_2024_2050_MOESM12_ESM.xlsx-MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
VCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
Portio vaginalis cervicis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8055
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6528
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13649
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0974
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07482
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8463
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29199
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37588
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00223
Nephridium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8032
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4611
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5176
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LE-40-JW92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33809
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.577205
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.371488
GSE143692_0_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20671
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0125
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05087
WDR45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51635
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14753
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.2887
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5651
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3719
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17169
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26713
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0641
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.779
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9916
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6022
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13965
TLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0618
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36603
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6843
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.149
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16974
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43663
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207742
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209986
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44293
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06961
NRBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54251
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38689
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9832
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4005
Clear cell renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1883
TUBGCP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01712
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267624
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.922436
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57867
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24369
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56827
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329002
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30843
GSE173201_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36063
COA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10489
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28854
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154577_7_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW-48 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.179
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254024
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4472
GSE234043_0_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20386
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
KHNYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27937
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1513
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5675
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1098
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20393
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3409
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0494
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34158
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10712
AXIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09717
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.48828
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4189
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229104
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4652
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Multiple synostoses syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32778
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14146
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7388
WA-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4442
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05685
PMC8530322-pone.0258316.s002.xlsx-GG_776_no-AA_776_no-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50183
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5361
GSE182382_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19896
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1881
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226173
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06811
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249248
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07643
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hodgkin's lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89026
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5036
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79569
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35791
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.475863
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3782
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14591
GSE169205_0_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8867
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22639
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.261
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13617
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7497
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26722
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9424
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34514
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14301
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360255
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4339
GSE121198,GSE129779_0_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10192
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232516
GSE144484_0_v_1_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9852
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.2811
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47388
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.967
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6281
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8344
RTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48882
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05933
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10701
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5875
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04375
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9705
Nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.513
ISCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38008
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1202
PMC8635809-Table_2.xls-LPS-downregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05899
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
THOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61596
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.624959
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9886
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4773
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206956
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226615
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.2
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38912
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7364
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4894
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22937
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0553
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8530322-pone.0258316.s002.xlsx-GG_778_no-AA_778_no-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32647
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3853
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.007
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98962
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19633
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.6082
GSE227592_0_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6694
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.81
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17351
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	1.21906
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44283
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.37511
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6407
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.944
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2952
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.422
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5934
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33621
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spondyloepiphyseal dysplasia tarda	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23258
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9495
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3503
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8499
WiDr cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94622
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03273
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51289
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7365
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290469
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52701
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3999
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.783151
PMC12612227-41523_2025_836_MOESM1_ESM.pdf-43-ZNF699_ZNF699	Rummagene Transcription Factor Associations 2026	1.0	null