association	dataset	threshold value	standardized value
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.73485
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.57995
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4759
Coats disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0
GSE115542_2_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Diffuse midline glioma, H3 K27M-mutant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9375
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
GTEx AdiposeTissue 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	4.55633
CENP-A recruiting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.354
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_I-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Shigellosis	KEGG Pathways 2026	1.0	null
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.006
Facioscapulohumeral muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1792
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
Neutrophil extracellular trap formation	KEGG Pathways 2026	1.0	null
Extravillous trophoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anus benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
Transcriptional misregulation in cancer	KEGG Pathways 2026	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.878
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.635
nucleus	GO Cellular Component Annotations 2025	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9299
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
Alpha thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
PMC5446900-NIHMS72240-supplement-Table_S1.xlsx-Table_S1-Table_S1_Genes_differentially_expressed_in_human_primary_myoblasts_upon_ectopic_expression_of_DUX4_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.315
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5624
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.13
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3679
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.761
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0594
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1213
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5007
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.988
Histone mutated tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
Facioscapulohumeral muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.075
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
h4s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
chromosome, centromeric core domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.627
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8579
Floating-Harbor syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9974
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
Musculoskeletal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5693
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2454
Trophoblast stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
KLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_UCEC_NOT_CESC_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
MutSalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
U7 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.842
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4643
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0377
PMC10800016-table_s5_20230913_ddad186.xlsx-FvsC_-_DUX4_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_4_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.692
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Systemic lupus erythematosus	KEGG Pathways 2026	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zika virus congenital syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
496100664_HIP_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.79238
CENP-A containing nucleosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.646
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.492
GSE221101_1_v_0_hopx_human	RummaGEO Gene Perturbation Signatures	1.0	null
INO80-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.058
Germinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	12.494
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleosomal DNA binding	GO Molecular Function Annotations 2025	1.0	null
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S23_LF_C1_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Facioscapulohumeral muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.13
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8355
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CENP-A containing chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.627
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.5028
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.901
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Swr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.168
Helsmoortel-Van Der Aa Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Alcoholism	KEGG Pathways 2026	1.0	null
FACT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.512
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.8207
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6961
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0357
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3196
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6141
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3111
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
Chondroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.787
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
senescence-associated heterochromatin focus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0425
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03659
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Ino80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2565
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.567
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5976
Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
h4ii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
alpha-thalassemia myelodysplasia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
Alpha thalassemia-X-linked intellectual disability syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
PMC11216401-Supplemental_figures.pdf-11-KLF17_KLF17	Rummagene Transcription Factor Associations 2026	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5131
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Connective tissue benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
TOM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.874
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9992
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.636
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3461
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.962
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1781
PMC11216401-Supplemental_figures.pdf-4-KLF17_KLF17	Rummagene Transcription Factor Associations 2026	1.0	null
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chondroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.05
Methylosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
b18	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4674
G-401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.696
Lsm1-7-Pat1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.002