association	dataset	threshold value	standardized value
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2127
A549_Resveratrol_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142204
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05433
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.900375
20490655-ST3	GeneSigDB Published Gene Signatures	1.0	null
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
MYOG_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870212
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.26036
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90355
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01534
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844553
RBBP5	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1468	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K30467307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24954
CRCGN015_MCF10A.TP53.M_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82505
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.63064
KM12	CCLE Cell Line Gene Expression Profiles	1.0	1.45489
Perturb_160_KD_Ago2_SRP259987	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.76172
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06375
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10416
KAT2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30078
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.48536
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.973603
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
MRC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509564
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930118
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r2 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00558
DBTRG-05MG	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59481
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526956
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15785
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE185865_0_v_1_celf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_3_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.264
CRCGN013_HEPG2_24H:F06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29567
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.14468
18631401-TableS3	GeneSigDB Published Gene Signatures	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62572662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52648
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440028
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892969
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56485
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40997
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3WB-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53129
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26673
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.73803
wm115	HPA Cell Line Gene Expression Profiles	-1.0	-1.21525
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162269
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8171
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.24236
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51519
BRD-K34595206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05581
Nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.852388
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71756
GTEX-T2IS-0226-SM-32QPH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02252
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21298
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227394
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41563
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44808
GF-46-LK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409361
A549_MLN8054_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172819
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32583
Cancer of prostate_Prostate_GSE1413	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66471
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03533
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89793
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916529
A549_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161662
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.76098
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61149
DA-58-LZ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371072
BRD-K34311186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1314
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1364
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78174
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895572
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18849563-SuppTable5b	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MP-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A61864215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32002
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39751
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.12835
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829757
GSE148269,GSE148273_0_v_1_arid4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217319
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65654
KLF1	ChEA Transcription Factor Targets	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89793
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05898
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03095
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61942
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00118
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559339
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45272
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.36968
18849563-SuppTable5a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K50432649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12162
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85311003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22314
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68847
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.979264
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13141
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.697
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42567
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr10_121928637_A_T_b38	GTEx eQTL 2025	1.0	1.42469
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15899
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61743
regulation of chromosome organization	GO Biological Process Annotations 2025	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903805
Perturb_4615_KD_Mlx_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.48997
GSE199606_1_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07152
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nse4/EID family	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-SNOS-0726-SM-4DM5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934885
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950506
BRD-K14799424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07212
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638943
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37769
Perturb_1018_Mut_Tspan2_SRP285017	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.51633
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42928
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.84098
NANOG	ENCODE Transcription Factor Targets	1.0	null
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09756
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.831987
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.505839
GTEX-XPVG-1326-SM-4B65P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73612
RT4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.76694
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974106
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-46-YF32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252467
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DC-49-EJ23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320584
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.911508
Helper T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.009
GTEX-TMMY-1226-SM-4DXT6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973936
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03438
valproic acid_mus musculus_gpl1261_gds3002	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BL1121 (SMC6)	NURSA Protein Complexes	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
betamethasone-valerate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05366
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.13301
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23106
CRCGN016_MCF10A.TP53.M_24H:H12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05263
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0892
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11018
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2096
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.86169
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59297
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876803
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877504
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68663
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0665
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
15474998-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36642
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.79956
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72255
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
STK33_knockdown_50_GSE15151	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.36136
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96505
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW1	DepMap CRISPR Gene Dependency	1.0	2.07531
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88411
BRD-K13336710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88038
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7214_KD_RC3H1/RC3H2_SRP058191	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.36553
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.36931
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.941747
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28777
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18535662-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640358
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49051
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68072222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32502
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MOLP-8	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.5748
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11298
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00907
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.908139
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2477
JHU011	DepMap CRISPR Gene Dependency	1.0	2.24315
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189599,GSE196004_0_v_1_bend2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.82389
BRD-K87126326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17433
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12227
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15946
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04095185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0516
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.40194
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849738
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73769678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23346
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876105
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2478
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.630062
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.709
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K88881681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42257
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199606_1_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB468	DepMap CRISPR Gene Dependency	1.0	2.03126
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.53077
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534992
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24858
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71937
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZD-78-BS65_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300333
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29628583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.171
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25608
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08185
B-cell chronic lymphocytic leukaemia-small lymphocytic lymphoma_Peripheral blood mononuclear cell_GSE8835	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.43221
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.6556
BC-72-DZ30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213177
NCI-H2227	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.32783
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ADH1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596323
A549_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213648
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955673
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14201
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4628
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862253
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934929
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.33295
BRD-K91094904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59625
BRD-K69826976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62415
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LoVo	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.95421
FOXO1_01_321	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61744
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21914
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13805
Kidney Chromophobe_KICH_TCGA-KL-8326-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TARDBP_02_129	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60196
BRD-A86629089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57482
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57586808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08347
STAT3	ENCODE Transcription Factor Targets	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93737
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19295
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21659
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18637162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22529
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26905
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61089
BRD-K07691486_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34088
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95009
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832684
BRD-A33119430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20583
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21062
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844749
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.11081
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83163
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58562
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9218
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K99131664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01524
NSMCE2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04935
FOXO3	ChEA Transcription Factor Targets	1.0	null
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08964
NR3C1	ENCODE Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4114
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39987
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895572
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
SF3B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697884
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50210179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49593
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34434
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312437
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58946
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15127
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.36417
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20741
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20219
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.79591
BRD-K87947740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36729
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05211
NU-DUL-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.93186
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02581
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34942615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13913
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39508
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376471
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24519
hsa-miR-222	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
BRD-K67336565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22213
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68668
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5829
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30992744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07629
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2415
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH2066	CCLE Cell Line Gene Expression Profiles	1.0	1.39565
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CB-44-RT90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209621
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36223
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.912952
BRD-K02921955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55785
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1259
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.391196
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13491
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54265757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11961
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8253
BRD-K77252933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0881
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17536501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01462
BRD-K04771555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53257
BRD-K36190163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14292
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8841
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49548
GTEX-RU72-0626-SM-46MUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974381
CRCGN015_HEPG2_48H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31487
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chromatin looping	GO Biological Process Annotations 2025	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06157
certolizumab pegol_homo sapiens_gpl570_gse33585	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-28-SS67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213235
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73125
Brain Lower Grade Glioma_LGG_TCGA-DB-A64X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74568359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5742
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05541
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891772
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15424
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75644
MAD2L1BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00442376
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06704
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	1.37012
CRCGN014_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21535
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02649
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.699172
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46806
CRCGN016_MCF10A.TP53.M_24H:B18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05668
NR3C1_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71819
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE62974_1_v_0_epas1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30432
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17683608-TableS2	GeneSigDB Published Gene Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.05298
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0274
MAP2K1_knockdown_105_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.80341
BRD-K49108064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27042
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A470-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09396
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
A549_Zileuton_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0223613
SJRH30	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.55722
bexarotene_homo sapiens_gpl96_gds2777	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SIU7-1326-SM-4BRWW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42905
A549_Panobinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122104
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4755
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9271
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868369
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28595
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922106
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLE	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.1554
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867342
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14813
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24433
BRD-K93788137_PF-431396_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.604387
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.49529
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MST1R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556784
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41504
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.374
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.61806
regulation of telomere maintenance	GO Biological Process Annotations 2023	1.0	null
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21732
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29443
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.637
POLR2AphosphoS5_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09536
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2613_EMC3_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.560731
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30499
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86619
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965574
Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13646706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67501
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82079
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49905
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977624
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68295
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31238
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931535
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-TFDP2_TFDP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199644_3_v_1_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13277
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25039
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.91948
MYBL2	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83953
HMGN3	ENCODE Transcription Factor Targets	1.0	null
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03061
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09297
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38584
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.25059
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.83247
CRCGN015_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.11457
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861088
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37407
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D1_1084_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
INKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33519
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205963_0_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMM1	CCLE Cell Line Gene Expression Profiles	1.0	2.58061
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.36402
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.14336
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965223
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC-20	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.88323
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56036
5659_NGDN_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.647982
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53036
Oligospermia	CTD Gene-Disease Associations	1.0	1.18849
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02145
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21547
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09125
BRD-K22800340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32136
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889749
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	2.09241
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2392
CRCGN015_HEPG2_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82955
A172	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76273
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88773
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99534
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.36443
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38842
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21434
Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79811
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833672
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU213	DepMap CRISPR Gene Dependency	1.0	2.12308
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05618
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895572
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38858
KDM5A	ENCODE Transcription Factor Targets	1.0	null
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6457
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41991
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27017
BRD-K66717300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.019
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828624
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06938
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.41638
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.78974
MOLT4	CCLE Cell Line Gene Expression Profiles	1.0	2.5576
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29514
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46307
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31951
GTEX-R55D-1526-SM-48FEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01813
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	2.14011
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68B-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.87332
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.14351
RERFGC1B	CCLE Cell Line Gene Expression Profiles	1.0	1.70595
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33554
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51369
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A549_Entinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156569
BRD-K69291887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87074
MAGEC2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.896
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11288
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Distal 10q deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.57
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13632
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37491
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971987
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35702
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.33682
BRD-A23345137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11041
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25596
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891381
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62236
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1308
CRCGN014_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39901
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626664
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33606
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21668
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
egr1_20019881_retina_lof_mouse_gpl1261_gds3607	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.042233
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0912
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42917
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pirinixic acid-495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2811
pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
rectum_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.24824
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0572
BRD-K85242441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21737
TOV21G	CCLE Cell Line Gene CNV Profiles	1.0	1.55138
BRD-A08759443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59942
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45823
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08137
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24616
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02003
Inflammation	CTD Gene-Disease Associations	1.0	1.28395
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.11775
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE255680_2_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93664
LS411N_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.57947
SLC25A34	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605298
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08281
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43395
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82081
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.972942
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3267
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3503
esr1_21299862_mcf7_lof_human_gpl570_gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.798458
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02764
S0-EE-Y6Y9_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212779
Nucleoplasmic periphery of the nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
Perturb_8385_KD_USP22_SRP213120	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.15319
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7176
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68056
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39013
BRD-K74918080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24924
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828667
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.64802
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34245
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.55727
Perturb_7785_KD_MTREX_SRP043962	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.31895
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1256
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.91971
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7215_KD_RC3H1/RC3H2_SRP058191	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.00762
TAF1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chromosome, telomeric region	GO Cellular Component Annotations 2015	1.0	null
precommissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0999
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05433
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06435
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900573
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920934
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7583
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3675
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4605
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210885_5_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877135
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06608
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.85445
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-2.70802
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30594
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55158
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14551
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1696
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07735
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	2.19936
BRD-K16268355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0935
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE-78-XD40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255876
CRCGN017_MCF10A.WT.HP_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4335
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46655163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30097
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13757
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36874
dna repair	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1666	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.58153
PMC8045971-Table_3.xlsx-vs_LPS_ctrl-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08097
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52556
COLO792	CCLE Cell Line Gene Expression Profiles	-1.0	-2.61808
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43581
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.422
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.479294
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573871
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10253
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02812
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.895879
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	1.0	1.37044
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54881
BRD-A04258855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17404
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.72025
SNU1066	DepMap CRISPR Gene Dependency	1.0	2.12739
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
biological_process	GO Biological Process Annotations 2015	1.0	null
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4692
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25619
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09604
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.20976
PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-DDR_Genes_AND_HNSCC_HNSCC_DDP_NOT_CCNE2_related_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Metabolism of proteins	Reactome Pathways 2024	1.0	null
nuclear part	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13066
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21004
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41382866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21456
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04957
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30754
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497055
BRD-K95574976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0463
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.9403
CUX1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71391283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06228
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.47023
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	2.07827
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
SW1088	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.8124
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31979
E2F1	ENCODE Transcription Factor Targets	1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hel299	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
A549_Iniparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173944
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.00966
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15374
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08089
NCI-H211	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.26225
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Condensed chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885135
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.11877
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
astrocytes	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.843275
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57818
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	1.25423
BRD-K40558736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09869
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80057
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33992
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69191
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31052
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36112
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01891
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04484
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876524
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein sumoylation	GO Biological Process Annotations 2025	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23184
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0537
HS751T	CCLE Cell Line Gene CNV Profiles	1.0	2.36724
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18835
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
DB-41-IH69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245786
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944691
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35617935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09362
BRD-K47261271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05434
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886264
BRD-K51012353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0872
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.714049
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917023
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03261
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05694
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15355_OE_RUNX1_ERP106519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33385
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.316
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986119
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3963
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08283
BRD-K65445351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8793
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6045
BRD-K03352392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48647
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22065094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12795
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02383
FOXA2	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30393
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67565
T98G	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.25494
Mitochondrial trifunctional protein deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934947
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0779
CRCGN016_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08666
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.28027
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866609
S0-EE-Y79N_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429153
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73016
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43318
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
UACC62	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11829
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14647
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.94679
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.78425
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRS2_KO_GDS1219_304_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mantle zone of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59813
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865357
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38855
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917935
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
response to stress	GO Biological Process Annotations 2015	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36552
Smc5-Smc6 complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68921379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06889
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21796
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826829
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950506
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.902554
Perturb_6589_KO_Zfp708_SRP186171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.75175
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19580273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49789
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273098
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01027
BRD-K93675803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21971
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.08069
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01837
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
double-strand break repair	GO Biological Process Annotations 2025	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
OCIAML3	DepMap CRISPR Gene Dependency	1.0	2.03766
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52098
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18767
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4296
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91831
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.528484
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.35422
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45543
BRD-K23478508_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RecQ family helicase-topoisomerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
BRD-K20906316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75282
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.05022
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887713
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68021
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01336
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.421
BRD-K81925504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31816
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54312
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.469
organelle part	GO Cellular Component Annotations 2015	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CCDC51	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517194
CCK81	CCLE Cell Line Gene Expression Profiles	1.0	1.40052
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73336
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833643
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7001
BRD-K20284960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18457
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07735
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957328
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26581
TF1	CCLE Cell Line Gene Expression Profiles	1.0	1.79184
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98088240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45229
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
MDST8_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	6.27289
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
condensed chromosome	GO Cellular Component Annotations 2025	1.0	null
16651414-Supp3	GeneSigDB Published Gene Signatures	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09861
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68378
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47391428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20036
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07547
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2803	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.17675
CAMKK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471942
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63054
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01278
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A673	DepMap CRISPR Gene Dependency	1.0	2.09852
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08221
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862836
PMC12697342-jem_20250471_tables3.xlsx-large_int_SM-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-WK-A8XX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-800	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.06972
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1872
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71041
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169590_6_v_5_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52466
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898629
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.33877
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998641
CAL33	DepMap CRISPR Gene Dependency	1.0	2.15217
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.554
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.55406
km3	HPA Cell Line Gene Expression Profiles	1.0	1.05817
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13143
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62052
ATF3	ENCODE Transcription Factor Targets	1.0	null
Perturb_14791_KD_SF3A2_SRP191866	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830982
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12306
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	3.31268
GSE116299_6_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72209
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946091
CRCGN008_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74515
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2553
CRCGN015_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59581
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26383
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34484
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06815
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBe1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.11942
MM386	DepMap CRISPR Gene Dependency	1.0	2.34421
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976119
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3909
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PEO1	DepMap CRISPR Gene Dependency	1.0	2.48063
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11825
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41516
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25343
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4761
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.992583
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203434
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.683133
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00655
Lesch-Nyhan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.7777
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-1326-SM-3NB2T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78539
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28165
Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89660028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1295
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12592
BRD-K79904333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04112
SUZ12	ENCODE Transcription Factor Targets	1.0	null
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HS742T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98436
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33101
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50187
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237679
Heart Diseases	CTD Gene-Disease Associations	1.0	1.15391
BRD-K27543887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48926
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14216332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93168
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.32664
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.948884
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42933
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34416
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-487a	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
hsa-let-7b-5p	MiRTarBase microRNA Targets	1.0	null
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45938
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939057
BRD-K82681356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40237
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19518
BRD-K77554584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61955
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.470058
BRD-K59778279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10897
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4224
parahippocampal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91673
LN-405	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.44384
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04763
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908693
Field CA1, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31755
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.8651
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.54712
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.75548
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20399
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_S-Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158698
BRD-K54233340_Dorsomorphin dihydrochloride_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inclusion Body Myositides_Muscle tissue_GSE3112	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.37439
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02423
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07231
BRD-K43390655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71542
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CI-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.12185
GTEX-S3XE-0826-SM-4AD4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36154
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876196
chromosomal part	GO Cellular Component Annotations 2015	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390778
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224312
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.87818
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.860098
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85227
chromosome, telomeric region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31592
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42139
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877504
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.15856
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
chromosomal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ORM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599463
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUMOylation	Reactome Pathways 2024	1.0	null
HLA-DQA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658297
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28834
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	-1.0	-1.22618
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04034
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5381
BRD-A80502530_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.025
NETO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601236
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911101
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30548
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.81639
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83483
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45702
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08635
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06855
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.26845
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
NRF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04721
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-PATZ1_mod_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37871
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56939159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2429
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95146
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.70005
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08323
PEER	CCLE Cell Line Gene Expression Profiles	1.0	1.52983
A549_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166397
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K77023196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00779
Brain Lower Grade Glioma_LGG_TCGA-HT-A614-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05272
RBM48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32881
foxa1_21151129_mcfdash7_lof_human_gpl10558_gse25315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.14868
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
SR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18185
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244832
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29371
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903954
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03694
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17818
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14316
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14991
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7775
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01713
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.3002
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92628
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48562
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.870367
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4878-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836584
BRD-K64434200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11298
PPARA_Deficiency_GDS2934_632_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11187
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.662474
BRD-K43389698_BMS-387032_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4909989-ncomms11840-s3.xlsx-Sheet1-The_overlapped_genes_regulated_by_YAP_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869161
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55347
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCV_8week+IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39844
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78301
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-DREAM_target_genes_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2429	DepMap CRISPR Gene Dependency	1.0	2.29058
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13575
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12295
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5144
BRD-K28093873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01616
BRD-K09074846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25028
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836487
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCUR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00446099
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_2_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17871
Tripartite attachment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.933
HMMR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530283
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831913
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.48374
CRCGN017_MCF10A.WT.HP_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93038
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910815
SARS-dORF6_84Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.63321
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7158
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27534
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RA-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875014
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29172
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.778
8903_TIAL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.570247
response to stimulus	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359792
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.47913
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43282617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07572
GSE189941_1_v_0_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-71-CQ35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331404
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26245
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.14529
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.714125
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SJRH30	CCLE Cell Line Gene CNV Profiles	1.0	1.58839
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.432
RL952	DepMap CRISPR Gene Dependency	1.0	2.41708
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
8288_SOX2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.660475
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146687_2_v_6_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75275329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07928
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1531
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12846
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00252
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK33	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K99221119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54132
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2591
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935274
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	292.46
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OVKATE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76987
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233976
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6573
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21325
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02765
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39775
hsa-miR-548ae	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664484
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59845
NDNL2	Pathway Commons Protein-Protein Interactions	1.0	null
DKMG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75178
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837471
BACH1	ENCODE Transcription Factor Targets	1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.75283
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24353
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39065
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89552
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22828
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10562
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.771
Chronic lymphocytic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
BRD-K84478344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65515
DF-00-BX35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307112
Scheie syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.548026
Brain Lower Grade Glioma_LGG_TCGA-CS-4943-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68465
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE185881,GSE185884_2_v_3_ctcf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2343
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.37724
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.22342
BRD-A67552019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5739
BRD-K44521151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06331
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.22112
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35662
18849563-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
Sarcoma_SARC_TCGA-MB-A5YA-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
SLC25A27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52524
GC-74-QF56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29734
NFKB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04944
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22431
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of DNA metabolic process	GO Biological Process Annotations 2023	1.0	null
PMC10828394-41698_2024_509_MOESM1_ESM.pdf-88-NRL_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835782
pancreas	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
PLK3_knockdown_121_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.8647
SRPK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839391
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5596
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5702
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946963
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952716
CRCGN017_MCF10A.TP53.M_24H:J04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62168
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864077
NSMCE1	Pathway Commons Protein-Protein Interactions	1.0	null
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08826
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	1.0	1.00434
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863474
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42648
RFX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
liminal part of the r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28834
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.42975
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.674
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77468
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5406
TEAD4	ENCODE Transcription Factor Targets	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1419	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50046
REST	ENCODE Transcription Factor Targets	1.0	null
CRCGN011_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4171
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46493
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01989
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3281
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.16664
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of chromosome organization	GO Biological Process Annotations 2023	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2415
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.841
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Endothelial cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.99338
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60982
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10469
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4PP-0726-SM-3NM9S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910446
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19116
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05563
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.88569
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885135
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GZMH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554239
Acute Myeloid Leukemia_LAML_TCGA-AB-2949-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09288
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.494511
KB-77-BA46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213827
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.176747
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9577
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9003
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948093
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60138
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55112
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
GTEX-TKQ1-0526-SM-4DXTG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58395
OB-06-WW76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406552
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.69807
BRD-K13543055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0184
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448988
recombinational repair	GO Biological Process Annotations 2023	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297191
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923423
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bipolar Disorder_Cerebral cortex_GSE12649	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44885
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31055
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.507754
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12065
BRD-K03116744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31975
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952096
PAX3	ChEA Transcription Factor Targets	1.0	null
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31984
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06792
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834155
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2626
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10945
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.884677
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00196
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302189
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15364
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922272
YY1-21170310-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22802
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22626
LN464	DepMap CRISPR Gene Dependency	1.0	2.19567
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90355
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914043
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE126127_2_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.38661
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dna metabolic process	GO Biological Process Annotations 2015	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875838
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28378
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59145
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.46258
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50641
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7048
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00554
Nse4/EID protein, Nse3/MAGE-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.51854
4h_cisplatin vs ctrl_mESC (Mouse) [22006019]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54086
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49051
IE-38-FB31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356078
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922442
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.978618
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09036
hsa-miR-409-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
9687_UTP6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.574688
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.38071
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_5_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286666
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1479
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18836
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35176035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29723
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46232
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40907
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.39412
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06608
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52285
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839593
BRD-K89967940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46207
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21286
hek293	HPA Cell Line Gene Expression Profiles	1.0	0.860177
CRCGN014_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.02529
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9742
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92062
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915794
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70959
CRCGN016_MCF10A.TP53.M_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39193
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.89649
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892919
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23115
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
AF-80-GK24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331598
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957628
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38331
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877831
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
BRD-K46619710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02422
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colon_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.999021
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.586431
GSE213048_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2906
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.90652
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37019305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52886
UOK101	CCLE Cell Line Gene CNV Profiles	1.0	1.39289
SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82888
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10037
hsa-miR-485-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49841
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4818
H3K9me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56106571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69643
CRCGN015_MCF10A_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26248
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85227
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10203
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890753
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60343
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60724
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.879847
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893492
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71125
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25174
BRD-K10704442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27293
E2F4	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smc5-smc6 complex	GO Cellular Component Annotations 2015	1.0	null
CAL27	DepMap CRISPR Gene Dependency	1.0	2.34719
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36764776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30499
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848024
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72638
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0387
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0726-SM-47JY5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960381
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19373
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63992
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27028
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-32 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
AB-02-CF97_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23078
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02785
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85035
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81110981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25
CRCGN016_MCF10A.TP53.M_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62632
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29451
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.76115
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7822
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78574327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14896
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	1.22553
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65059
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60007
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03898
GTEX-Q2AG-1226-SM-4GICA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872701
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922759
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892719
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73827
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530349
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32159
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15994
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15353
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.759809
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04259
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU1J-0526-SM-46MUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847978
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05712
BRD-K74927219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39394
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUMOylation of DNA damage response and repair proteins	Reactome Pathways 2024	1.0	null
BRD-A94756469_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08742
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.41035
BRD-A47963183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08697
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3355
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SK-LU-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.83921
GSE114992,GSE114993_4_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.980194
TLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39403
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30259
PMC3607232-mmc3.xlsx-b_RUNX1_SEM_MLLC_H3K4Me3-x_2_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-S7_Data_List_of_all_genes_that_were_upregulated_in_HEK293DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88O-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6687
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ac	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
GSE223008_4_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.097
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39285
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dinoflagellate epicone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
DOT1L_DELETION_GDS4295_427_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 5 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53365
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-2.06106
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02559
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46447
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K11942486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00708
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36364
A549_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133665
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47334
CCNT2	ENCODE Transcription Factor Targets	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18694
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.0637
Anemia	CTD Gene-Disease Associations	1.0	1.04978
DSCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37384
BRD-K58168959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19867
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33993
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67004
Adrenocortical carcinoma_ACC_TCGA-OR-A5LB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sw837	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04688
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.63609
hsa-miR-548d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70749
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62631
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.39953
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883089
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855815
BRD-K99545815_PF-562271_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29006
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36468
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1256
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of response to stress	GO Biological Process Annotations 2015	1.0	null
purine-pyrimidine metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.78404
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.40579
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84835
POR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599646
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52357
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20075
cell part	GO Cellular Component Annotations 2015	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497383
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02191
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68303
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77629
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22286
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36234
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9426_TUBGCP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.04915
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NC-27-AD53_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287156
20101236-Table2	GeneSigDB Published Gene Signatures	1.0	null
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.766
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57808
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEO4	DepMap CRISPR Gene Dependency	1.0	2.47974
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.714
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.842608
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07399
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAGEB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84761515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66855
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.32536
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.01025
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06821
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05484
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.81404
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.44663
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05433
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935796
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35101
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31751
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836317
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41426
Short chain acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20208
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213845
BRD-K30533903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06402
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94349
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847708
BRD-A46778020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34411
A498	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.27676
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH460	CCLE Cell Line Gene CNV Profiles	1.0	3.1103
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_14_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91485
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979353
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08056
PMC3435504-msb201237-s2.xls-Supp_Table_4c-TFDP2_TFDP2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-1226-SM-48FE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986795
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20476
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41551
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854742
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06253
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0005
cellular response to stress	GO Biological Process Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A7TX-01A-33R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCAS	CCLE Cell Line Gene CNV Profiles	1.0	1.64321
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06466
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32159
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Q7-0926-SM-4AD5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03149
A549_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140775
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.255
SRPK2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18411
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gemcitabine_homo sapiens_gpl96_gse6914	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861787
Ctf18 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274209
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274289
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23318
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944225
BRD-K78217164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5312
TTT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
SI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580811
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45735
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.28149
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51387
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15341710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33856
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18552
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41923
sc11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17893
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04034
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H1_Derived_Mesenchymal_Stem_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03791
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23321
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
BRD-A57594599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01854
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82777
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1569	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50061
A549_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154227
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40455
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04494
Perturb_858_KO_Lrp2_SRP134101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64909
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85967
BRD-K63626200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04877
Vicriviroc	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
BRD-K93374700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34428
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76964
Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smc5-smc6 complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18411
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1358
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K66941670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17615
GMFG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532937
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.67154
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904003
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25814
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosomal region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919558
18625725-TableS1	GeneSigDB Published Gene Signatures	1.0	null
mantle zone of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08137
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00186
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25039
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608577
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11707
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.650772
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	1.35097
CRCGN016_MCF10A.WT.HP_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21596
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6380_KO_Snf5_SRP271283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.2218
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92807
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14225
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.74741
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16993
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29006
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21906
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934641
GATA3	ENCODE Transcription Factor Targets	1.0	null
protein sumoylation	GO Biological Process Annotations 2023	1.0	null
3t6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994026
MOLP8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82902
Pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.3198
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49948
BRD-K88625883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45653
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-96-HO33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349024
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.357
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75094
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28124
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75387
A549_Decitabine_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00975408
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09216
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215916
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE127970_1_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227634,GSE228381_0_v_7_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPARA_KO_GDS2886_484_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7793
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271994
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A13122391_16-HYDROXYTRIPTOLIDE_PC3_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SERPING1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598897
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20286
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4G	ENCODE Transcription Factor Targets	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AKT1_knockout_210_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.71584
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30633507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75744
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918077
STAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575165
chr10_121972215_G_A_b38	GTEx eQTL 2025	1.0	3.25816
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4759
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42905
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54014
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56994
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92316
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11707
CRCGN017_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3298
Micropyle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
BRD-K93774122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20797
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.767
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-548aj	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1472
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01663
CRCGN015_MCF10A_48H:K14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0805
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68465
PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-FigS7d-CTCF_in_promoter_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.25362
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40061713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60252
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05699
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00215
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309207
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21465
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838899
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.4395
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Adrenal gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
BRD-K12411112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32732
BRD-K53198140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8667
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.07342
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	1.1736
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66585
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890679
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859341
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VCAP_PROSTATE	CCLE Cell Line Proteomics	1.0	2.86871
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291406
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31349
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90853
PML	ENCODE Transcription Factor Targets	1.0	null
H3K36me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.59729
C3A	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.31384
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05433
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1814
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17145
BRD-K82774801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05215
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64757
inner SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42345
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08117
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.643712
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2942
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29201
protein-containing complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K74129999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26652
USF1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18801
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.887
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889655
BRD-K11667893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21679
CRCGN008_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35025
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09949
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18849563-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HS834T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12433
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.08065
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13462
ADSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523406
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41295
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71298594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75622
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00276
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03277
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.61093
GTEX-PSDG-1426-SM-48TD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2077
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32838
RS5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67233
AB-04-NN16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236341
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.919712
GSE128333_2_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
molt4	HPA Cell Line Gene Expression Profiles	1.0	0.844998
BRD-K10182289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14921
IE-38-FB31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326324
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21915
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.846905
GSE220520_3_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.29849
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72705
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25169
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630939
GSE90754_0_v_1_foxo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80816
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913879
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844502
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60278
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRCA1	ENCODE Transcription Factor Targets	1.0	null
BRD-A34806832_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05022
HSMM	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.0221
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200205
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454718
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.42946
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272247
mantle zone of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7842
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965119
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2453
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03203
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92626
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAGEA1	Pathway Commons Protein-Protein Interactions	1.0	null
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11234
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61553
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05048
A549_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164407
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.920017
BL1145 (LMO1)	NURSA Protein Complexes	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.44284
Lung transplant rejection_Lung Tissue_GSE2018	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59591
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42285
BRD-K89432538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34496
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38408
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46986
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5217
CDK6_knockdown_93_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.70726
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00778
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903318
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AIFM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579065
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A69950438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42403
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57299
BRD-K64800655_PHA-793887_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07817
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43223
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01557
SW1990	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.27918
r8 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32895
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904863
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914693
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-AAQO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829689
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06329
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963824
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
SPIRE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762637
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A69L-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76755209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43397
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE1551	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.84889
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66482
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.41035
GCIY	DepMap CRISPR Gene Dependency	1.0	2.0217
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267265
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868767
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
BT20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45703
BRD-K58532728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0823
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15363
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUMO-targeted ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
UMUC1	CCLE Cell Line Gene CNV Profiles	1.0	2.59865
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11888
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.97249
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61416283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06389
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841773
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825765
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12295
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RIPK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948927
NCI-H510A	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.5704
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06097
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74611
BB30HNC	DepMap CRISPR Gene Dependency	1.0	2.53841
hif1a_16565084_mcf7_lof_human_gpl2507_gds2761	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.307128
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42243
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75562
BRD-A09975616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64164
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02985
RPL19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00731834
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56096
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.47375
DNA metabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992283
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67918
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19593
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.22721
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460177
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.843434
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82244940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26912
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83481
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24598
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45539
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16325
EGR1	ENCODE Transcription Factor Targets	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.53204
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2553
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37474
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103372_1_v_2_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35365
BRD-K49707067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07878
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09095
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830006
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98298
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_2_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02709
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Dhori Virus_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.18192
BRD-K00808919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17294
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05124
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55875
19962670-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K30025024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73222
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_3_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04278
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09796
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21642
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2664
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40449
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_9_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16789
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.288
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7148
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00183
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29494
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.841
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02538
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914428
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32474
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92937
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
double-strand break repair via homologous recombination	GO Biological Process Annotations 2023	1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Tozasertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.013682
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48305
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.001
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.31686
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1203
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7187
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08368
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18042
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.05282
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.28739
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219176
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24799
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0541
BRD-K73689413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46796
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29479
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b95.8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1131
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12568
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40749
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20635
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17778
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04733
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36945
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38992
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RA-42-CM42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246557
lateral part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7842
BRD-K76885311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38232
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38287
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00702
BRD-K16136897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29901
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96032
ZNF384	ENCODE Transcription Factor Targets	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965574
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11087
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.98845
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6941
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38076
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412356
CRCGN017_MCF10A.WT.HP_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.11363
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38513
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6924
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71959
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1131
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.15416
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
A549_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161366
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39345
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3872
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRAK4	Kinase Library Serine Threonine Kinome Atlas	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63201
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49599
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AE-13-WW30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203026
CRCGN012_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2348
PMC7672319-mmc3.xlsx-DREAM_MSigDB62-FISCHER_DREAM_TARGETS_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
Cytoplasmic periphery of the nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
A498_KIDNEY	CCLE Cell Line Proteomics	1.0	2.05788
BRD-K63364685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61442
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7906
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98175
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36977
double-strand break repair via homologous recombination	GO Biological Process Annotations 2025	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515901
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71871382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0812
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50195
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04102
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02484
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.6017
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07354
ZNF394	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35348
Mifepristone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931351
BRD-K96997646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29693
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.69766
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17445
Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A07870296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98668
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06943
BRD-K66032509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49508
BRD-K40894545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13625
BRD-K54903703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35108
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4099-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.36933
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.33295
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08215
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42134
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	1.48931
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0926-SM-4IHKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10133
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495244
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341887
CRCGN013_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05906
BRD-K16496880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44723
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
ME-54-JY76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234245
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28371
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUMO ligase complex	GO Cellular Component Annotations 2025	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72015
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850106
MDA-MB-157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.92099
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.16
TEAD4_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34281
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.16136
RAD18	Pathway Commons Protein-Protein Interactions	1.0	null
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53376
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32895
TET1	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939778
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18192
BRD-K31748787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58017
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04784
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57127
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.695244
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1826-SM-4E3HV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20098
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888736
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42062
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	212.455
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.02661
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69741
GTEX-S7SF-0626-SM-4AD4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20164
RhoGDIbeta_KD_GDS2864_634_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4275
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8025
A549_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158957
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.83675
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.56392
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931564
BRD-K47658117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44592
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24322
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00269
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893731
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K11331752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29658
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22232
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849578
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.02725
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18505
BRD-K19327124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78664
BRD-K03957217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29987
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74157
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951032
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16876
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.25038
JIMT1	DepMap CRISPR Gene Dependency	1.0	2.0011
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.009
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1205
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05691
Geniculate group, dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31295
vorinostat_homo sapiens_gpl10558_gse35242	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841581
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23159
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPD - Chronic obstructive pulmonary disease_Bronchial epithelium_GSE3320	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.90927
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-1026-SM-48TCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17796
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10366
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03593
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78919
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61348
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00589
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.76045
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.17871
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SUPB15	CCLE Cell Line Gene Expression Profiles	1.0	1.38879
BRD-K43170571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13635
BRD-K12440228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46411
BRD-K64055724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88222
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.915217
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07826
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.631555
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15564
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
LU-134-A	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.35046
5830_NSMCE4A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.592302
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5504
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77004
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849939
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27129
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63327
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08064
15297395-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.76208
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07718
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09068
CRCGN010_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01019
BRD-K64591035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0662
MYOG	ENCODE Transcription Factor Targets	1.0	null
BRD-K18402224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.315
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08437
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45157
BRD-K23166347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53004
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3962
BICR78	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.78053
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0623
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2337
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.65613
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1990	DepMap CRISPR Gene Dependency	1.0	2.34084
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65158
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958405
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13459
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.908806
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.15965
chromosomal region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.006776
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.16739
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH1_LIVER	CCLE Cell Line Proteomics	1.0	2.0053
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59392325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11894
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4521181-oncsis201520x8.pdf-29-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06208
SPIB	JASPAR Predicted Transcription Factor Targets	1.0	null
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67891
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0722
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840778
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249213
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4849-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EA-40-KQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421715
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-66-UB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301883
FOXO1	ChEA Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
recombinational repair	GO Biological Process Annotations 2025	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8775
hsa-miR-653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.91047
Subiculum, ventral part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05399
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08668
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02393
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919126
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endodeoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TE-12	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99773
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00509345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.107
double-strand break repair	GO Biological Process Annotations 2023	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43563
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69908
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28326
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7848
GSE201042_6_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965574
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18827
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.2711
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25328
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3118
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19352
BRD-A93236127_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3156
SLC7A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062865
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.23822
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06296
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876972
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49165
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150833
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38378
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.34498
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10938
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21403
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72371
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30786
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.195957
BRD-K32403948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16468
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.03505
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947665
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38779
PSN1	CCLE Cell Line Gene CNV Profiles	1.0	1.40264
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887123
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.955295
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971326
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
condensed chromosome	GO Cellular Component Annotations 2023	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56161
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.25498
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15686_KO_Stat1_SRP277338	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_84Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45297
A549_EED226_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143322
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K03312699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83469
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05221385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33799
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55664
BRD-K10160311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18279
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3397
Non-structural maintenance of chromosome element 4, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9756
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855553
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BTN3A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513751
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11646
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0093
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872052
BRD-K38861721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18464
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11787
Ezh2_KO_GDS3765_515_mouse_Primary preadipocyte cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
3234_FYTTD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.578929
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02571
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10458
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37628
GSE103372_0_v_3_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.56659
Edema	CTD Gene-Disease Associations	1.0	1.07163
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
MAP2K1_druginhibition_172_GSE39984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.45887
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5403
Learning Disorders	CTD Gene-Disease Associations	1.0	1.11151
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.58557
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05495
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1879
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A42246453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62066
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906065
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69801
Uterine leiomyoma_Uterus_GSE2724	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.97474
H3255	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.60138
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02061146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01479
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE208226,GSE208227_2_v_1_ell3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.253375
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.98156
cellular process	GO Biological Process Annotations 2015	1.0	null
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62068
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.59795
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HQ-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVK18	CCLE Cell Line Gene CNV Profiles	1.0	1.47734
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10776
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7925
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78237
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2405
pyramidal layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15156
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K65265098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11123
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1595
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66295
JD-10-HW02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215051
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169155_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972907
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.02884
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22388
GTEX-S341-0426-SM-4AD5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827817
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.72001
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34687
GOS3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50673
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07375
A549_Streptozotocin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161459
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66124
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65996
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6487
BRD-A25243629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60783
Weight Loss	CTD Gene-Disease Associations	1.0	1.39394
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral lateral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15005
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05484
Elg1 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210885_3_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840212
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37228
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17588
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09555
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.4709
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53135
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3488
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957171
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsf1_17216044_hela_lof_human_gpl571_gds1733	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.400548
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61624
BRD-K91085913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21641
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157282_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.43835
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53808
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67205
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11847
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824243
WDR5-24793694-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AC-80-DI95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291998
BRD-K51754677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41119
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205332_2_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03154735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38103
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.956312
GTEX-XAJ8-0326-SM-47JYI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17523
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.3248
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2405	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.15895
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68668
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29754
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17556
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58708
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K74107343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03851
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832295
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0726-SM-33HBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33487
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39016
SUMO E3 ligases SUMOylate target proteins	Reactome Pathways 2024	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.73633
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895572
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45626
BRD-K14778436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68705
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.23195
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66179
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.10091
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3676
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98932
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6683136-41598_2019_47363_MOESM2_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1-AS1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994026
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12418
CRCGN015_HEPG2_48H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50556
Fatty Liver	CTD Gene-Disease Associations	1.0	1.07696
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31881
STAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557146
GTEX-TKQ1-0426-SM-4DXT4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08769
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Smc5-Smc6 complex	GO Cellular Component Annotations 2025	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42157
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19239
Perturb_12997_KO_rs2431697_ERP121303	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.44367
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6654
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.562441
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.02189
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62618
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963824
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2615_Mut_SF3B1_SRP249914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.9587
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36343
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14048
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26393435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89153
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35746
7522_RPS2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.573477
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.249
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39233
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5235
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60834
BRD-K82409466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01771
CEBPD	ENCODE Transcription Factor Targets	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dna recombination	GO Biological Process Annotations 2015	1.0	null
17150101-TableS1l	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64669
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963824
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.29226
hsa-miR-4529-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-1126-SM-48TZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10474
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58677
RXRA	ENCODE Transcription Factor Targets	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.68127
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0974
regulation of response to dna damage stimulus	GO Biological Process Annotations 2015	1.0	null
A549_WP1066_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186035
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04522
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08324
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.96149
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885769
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05285
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943343
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40714
BRD-K50884475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11139
CRCGN015_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0119
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8171
AA-87-EI21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249941
EWSR1	ChEA Transcription Factor Targets	1.0	null
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
ATM_knockout_75_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.28338
BRD-K35708212_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11011
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94593
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64055457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59416
A-CA-04-2009(H1N1)_4day-RIPK3KO_None_GSE51526	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34321
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921923
NLRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00628584
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FMNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568198
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10351
HASPIN	Kinase Library Serine Threonine Kinome Atlas	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGS	DepMap CRISPR Gene Dependency	1.0	2.12861
BRD-A77941182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23928
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DNA damage response	GO Biological Process Annotations 2023	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61147
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971577
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02047
RMI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060926
Root apex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911154
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1119
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.13868
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.48197
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181749_2_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909303
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LB831-BLC	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.2792
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01567
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287824
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0626-SM-4KL1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971366
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55664
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71183
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33362
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15328
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4824-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23327
Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172058
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10189430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05197
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.69
GTEX-WFJO-0426-SM-4LVM7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1617
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	2.19653
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43023
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68511
BRD-K57315740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22669
CBX3	ENCODE Transcription Factor Targets	1.0	null
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15753
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.1862
A549_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136538
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93615
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
PMC6433297-pbio.3000178.s012.xlsx-DREAM_targets-BUB1B_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870427
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25441
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232944_1_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846902
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82434
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plastid-encoded plastid RNA polymerase complex A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828509
Nuclear envelope adjacent to nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20309
PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TCEAL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479936
BRD-K51287451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46096
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15658
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19325444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20812
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63054
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51755
DNA damage response	GO Biological Process Annotations 2025	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873053
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00232
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.352791
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.829548
MTA3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47273
BRD-K22608982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48671
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950506
A375_SKIN	CCLE Cell Line Proteomics	1.0	6.44277
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SUMO ligase complex	GO Cellular Component Annotations 2023	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LK-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.9554
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.542491
BRD-K16826019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46886
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94974
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43937
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02141
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18321
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R9-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157594_5_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68127
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.3412
BRD-K11219023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02115
BRD-K70052888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56059
GSE131565_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12551
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.84168
BRD-K43782839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01534
Spleen	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.30566
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.841
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53853
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86317
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0761
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A84816049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77516
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60185
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.658
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17775
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
A549_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176267
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.882834
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22789469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1546
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.609
hsa-miR-221	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35733
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04679
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205863
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2543
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14515
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11325
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974507
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.91876
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular response to stress	GO Biological Process Annotations 2015	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273007
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965887
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.72451
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910774
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05258
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925589
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25825
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0012
IRF4	ENCODE Transcription Factor Targets	1.0	null
plastid-encoded plastid RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.116
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917641
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02947
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-10-RFX1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0085
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00652
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.04749
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06549
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1441_CDK7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.62911
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
TUFT1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	1.54494
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19572
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35588
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.394
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.913968
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2156_KO_Tnfaip3_SRP126279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7712
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4166
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.971097
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31117
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73336
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00432
TT2609-C02	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.01513
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2123
Kallmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
PATU8988S	CCLE Cell Line Gene Expression Profiles	1.0	1.55473
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.891707
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52443
FD-35-PQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364989
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28907
BRD-K38097136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14967
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00252
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1145
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03435
WC-67-DI84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45411
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945688
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
12176889-Table1	GeneSigDB Published Gene Signatures	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46292
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23984
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.55186
D423MG	DepMap CRISPR Gene Dependency	1.0	2.13483
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DiFi	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.12723
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832858
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850374
LS411N	CCLE Cell Line Gene Expression Profiles	1.0	1.65186
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03085
CRCGN017_MCF10A.WT.HP_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49725
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91156
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K11812419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00037
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43945
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52927
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25338
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20087
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16876
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76194
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99486
Perturb_16396_KD_Yap1_SRP244345	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.24864
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIT_activemutant_55_GSE17743	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.85895
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22942
Perturb_5676_KD_Kdm5b_SRP362502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.34356
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23234
Parasubthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27201
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26824
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.093
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43041
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS822T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57198
AD-09-MD49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208306
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16795
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04704273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5388
Perturb_4614_KD_Etv5_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.1672
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994353
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN017_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.28687
Pons, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03469
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HECW2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE85302_0_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825248
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25528
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28469
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237528
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMK1G	Kinase Library Serine Threonine Kinome Atlas	1.0	null
BRD-K35469110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12146
G-402	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.11009
Nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
condensed chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.18659
GA-04-JM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.521726
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02139
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15403
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7964
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04757
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K04650671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08449
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35573
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22505
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23608
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38313
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50639228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1193
BRD-K00717406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53122
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6448
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55607
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.923311
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48076
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5853
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07711
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K92826631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40213
Mad-Max complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27762
BRD-K01278504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54089
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24455
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02208
BT-483	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.33495
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531594
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08109
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55884477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50849
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29671
LPS853	DepMap CRISPR Gene Dependency	1.0	2.36644
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3237
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3729
IC-80-CT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21265
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16876
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
A549_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157362
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48427
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.74836
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34816
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8744
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.41
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70717477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0965
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09973
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26114
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38115
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00067
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938353
BRD-A06158172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02701
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08826
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pontine reticular nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28912
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MELK_druginhibition_186_GSE50227	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.16777
protein modification by small protein conjugation	GO Biological Process Annotations 2023	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68386
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1916
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234228
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.04163
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912859
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Eukaryotic translation initiation factor 2B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10913
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8613_KO_Ctcf_SRP078142	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.25916
mantle zone of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01128
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TT-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50924315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94367
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16916
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84246050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62587
MCIXC	DepMap CRISPR Gene Dependency	1.0	2.08239
Weight Gain	CTD Gene-Disease Associations	1.0	1.12495
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.27045
OD-96-OP94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297825
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2519
AE-18-ZM98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205818
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.02263
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.35316
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32159
CRCGN017_MCF10A.WT.HP_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0922
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10115
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55257
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11442
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62011
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.389
BCL3	ENCODE Transcription Factor Targets	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.98821
BRD-K45022385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12847
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240809_0_v_1_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	0.863168
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26023
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1326-SM-4BOO1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03328
NCIH1437_LUNG	CCLE Cell Line Proteomics	1.0	2.79984
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70692
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824243
Necrosis	CTD Gene-Disease Associations	1.0	1.34547
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905707
GSE131649_6_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41946
r3 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96077
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30302
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02966
metabolic process	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2655
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951127
Leaf epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.34
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.39172
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115241
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62205
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.90086
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901578
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827174
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.889465
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45738
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
TEK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00487436
GSE160001,GSE160670_1_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BF-94-CQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329912
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HUH6	CCLE Cell Line Gene Expression Profiles	1.0	1.47922
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4054
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11704
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNSH	DepMap CRISPR Gene Dependency	1.0	2.14951
ATF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00463685
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBFOX2_02_101	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59131
Tassel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03895
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238262
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857652
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09459
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.77758
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18753
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.822733
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926791
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.55458
DNA metabolic process	GO Biological Process Annotations 2023	1.0	null
ARHGAP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37122
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A620-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05744
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.11019
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12313
CDK9_knockdown_104_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.90971
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20606
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01833
CRCGN015_HEPG2_48H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6468
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1-21170310-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96596828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03931
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27256143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42736
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876395
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20792
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
9482_UBA52_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.530869
GTEX-X5EB-1726-SM-4E3J7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85278
chromatin organization	GO Biological Process Annotations 2025	1.0	null
HCT116	CCLE Cell Line Gene CNV Profiles	1.0	1.65623
GTEX-U4B1-1226-SM-4DXT7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07059
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79961
16542501-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04256
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74705
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00821
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11707
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.984588
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972826
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84363
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16913
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44568
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89583
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54436
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37908
GTEX-WFG7-1026-SM-4LMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12128
RBM39_02_151	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59425
BRD-K74198088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12985
SP4	ENCODE Transcription Factor Targets	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K21356734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41691
WF-24-LG17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316026
chromosomal region	GO Cellular Component Annotations 2015	1.0	null
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06015
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDR_knockdown_119_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.41366
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6487
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07483
SYO1	DepMap CRISPR Gene Dependency	1.0	2.15881
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85603
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01621
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38573
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.488
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-39-ED84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340862
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3331
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66675422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07787
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830896
GSE143944_1_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890608
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25172
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.841
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EW16	DepMap CRISPR Gene Dependency	1.0	2.18501
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34463
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRE1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
DTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65342
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09963
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841317
prostate	GTEx Tissue Gene Expression Profiles	1.0	0.964608
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125219,GSE125221_5_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRANTA-519	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.83192
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.130666
GSE150215_1_v_2_etl4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
18849563-SuppTable5c	GeneSigDB Published Gene Signatures	1.0	null
H3K9me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_UNC0631_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188777
BRD-K52973286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98395
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15595
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21675
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548am	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09007
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01534
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0104522
CRCGN017_MCF10A.WT.HP_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4418
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_TGX-221_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192388
BRD-K45091989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09628
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STATH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0071862
BRD-K88802328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25163
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548x	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17858
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21146
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03694
Post-translational protein modification	Reactome Pathways 2024	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2477
CRCGN015_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0855
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0576
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A55574211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49116
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45887
SNU398	CCLE Cell Line Gene Expression Profiles	1.0	1.52852
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28258
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.25214
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.856
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92023
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387228
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81914
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56646
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.924222
CD37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00444778
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32482
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10717
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45569
GSE84175,GSE84176_0_v_1_ctcf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41935
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
S0-EE-XMXE_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30386
CRCGN017_MCF10A.WT.HP_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27475
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86177
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04763
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K20043699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37399
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UC-00-QA88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26469
15297395-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10009
p3hr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.51993
Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12343
HNF4A	ChEA Transcription Factor Targets	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58302
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877643
HS255T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73449
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883929
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853016
Perturb_12009_KD_EmbA_SRP361519	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.5577
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868033
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.831547
nb4	HPA Cell Line Gene Expression Profiles	1.0	0.878315
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KARPAS299	DepMap CRISPR Gene Dependency	1.0	2.39592
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42929
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03524
GSE149359_3_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00722
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PATU8988T_PANCREAS	CCLE Cell Line Proteomics	1.0	2.0371
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63713
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12171
TAF7	ENCODE Transcription Factor Targets	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MAGED2	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
CHAK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02561
BRD-K86008496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14359
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15809
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47883435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07456
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955098
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895809
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.03067
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.620105
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.9996
Nephritis	CTD Gene-Disease Associations	1.0	1.06917
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54046891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16894
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71453
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0422
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841997
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26067
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A78085235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14774
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54186
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65933
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64W-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Roxadustat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143579
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.34019
MFSD10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0040956
DNA repair	GO Biological Process Annotations 2025	1.0	null
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34532
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.12575
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1084
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16983
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
19294737-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35499
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.2639
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51437
rectum	HPA Tissue Protein Expression Profiles	1.0	1.41035
Perturb_17493_KO_Gpr115_SRP275685	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.89591
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.12131
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.82169
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.20961
IRF1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02584
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40119
DNA repair	GO Biological Process Annotations 2023	1.0	null
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64608
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parkinson's Disease_Substantia Nigra_GSE7621	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43325
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18375
Ascites	CTD Gene-Disease Associations	1.0	1.04352
adipose tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K75844518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0577
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.26667
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03266
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01813
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865471
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09007
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08952
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26383
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840009
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SPEG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611063
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61175
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59549
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928709
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73027631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15862
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26251
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_OE_GDS3444_576_mouse_Cultured embryonic stem (ES) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88765
GSE201217_3_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64232
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87331
Xeroderma pigmentosum group D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU520	CCLE Cell Line Gene CNV Profiles	1.0	1.38405
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF9_Deficiency_GDS2703_647_mouse_Jejuna - intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21518
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00683
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.987152
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01371603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29886
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66286
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81719
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02694
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978739
protein modification by small protein conjugation	GO Biological Process Annotations 2025	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01455
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1037
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866691
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00362
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05583
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FCRL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527063
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.996065
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2064
JAK1_activemutant_61_GSE18239	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82692
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24285
BRD-K24263752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49028
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of telomere maintenance	GO Biological Process Annotations 2025	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ChEA Transcription Factor Targets	1.0	null
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02163
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863485
intermediate stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16178
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48691513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24696
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56428170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17554
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903915
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.851106
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00869618
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.05604
A549_Cimetidine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142517
LB2518-MEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.84479
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12849_KO_Rnf114_SRP301146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.34687
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.72379
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18319
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84619
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7634
CRCGN017_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04708
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47181
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02616
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSL24D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669272
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16488
Leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62465
Holliday junction resolvase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25088
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484238
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.702
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9908
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691827
A549_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173048
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_YY1_22210892	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2171	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.43481
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00203
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39536
Roberts syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
GTEX-REY6-1426-SM-48FDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825363
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12107
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.66703
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175062
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21969
chromosome, telomeric region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SNU398	CCLE Cell Line Gene CNV Profiles	1.0	1.43067
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-05-LU10_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207297
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967848
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.818516
H2AC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81899
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212234
BRD-K19310540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81863
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SB-29-ZH97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228993
testosterone_mus musculus_gpl1261_gse17553	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.45258
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K00323141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14833
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00029
TD-69-UA90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393862
ELF1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90232
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.33063
BRD-A34891365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14849
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835917
Hypertension	CTD Gene-Disease Associations	1.0	1.1529
H3K9me3_U2OS_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SRPK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03609
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0904
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCN8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588961
Perturb_4750_KD_CDKN2BAS1_SRP243483	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.48345
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19116
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35272
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.983
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01352
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.302
DNA packaging complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.865
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07584
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
vitamin c_mus musculus_gpl1261_gse37676	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Iniparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146087
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.56524
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83942575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02027
BRD-K37831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19447
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53551
Cisplatin	CTD Gene-Chemical Interactions	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10562
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03497
SARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00436869
SLC22A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48068
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58446
18849563-SuppTable3a	GeneSigDB Published Gene Signatures	1.0	null
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15442833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03073
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67062
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934367
BRD-K44828787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08004
Platysma muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18301
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10572
BRD-K73831263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71933
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18644
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
liminal part of the r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59813
OVMIU	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.61487
peptidyl-lysine modification	GO Biological Process Annotations 2023	1.0	null
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86345
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06608
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09103
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887135
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.62034
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51938
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55075
A549_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198721
CRCGN015_MCF10A.WT.HP_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49635
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.39112
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ctcf_18614575_oocyte_lof_mouse_gpl1261_gse11664	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-2.35895
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63201
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24118
BRD-K52872067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81037
2367_DPY30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.41248
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75882
KDM4A	ENCODE Transcription Factor Targets	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288378
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55664
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PF382	CCLE Cell Line Gene Expression Profiles	1.0	1.45963
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07032
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21624
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K36884445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04952
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.12599
RT11284	DepMap CRISPR Gene Dependency	1.0	2.18012
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871133
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
PAX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21561
A549_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149351
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54565
nucleus	GO Cellular Component Annotations 2025	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02203
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874213
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34563
lateral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46346
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47806
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23437
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.884762
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95114614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0365
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61017
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16736
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24577
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-PATZ1_mod_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63813316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05113
HCC1897	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14855
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HUPT3	DepMap CRISPR Gene Dependency	1.0	2.3415
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27047
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07492
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664768
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-1426-SM-4B668	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61544
BRD-A71459254_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03837
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.87783
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06305
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amyotrophic lateral sclerosis type 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19701
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.59042
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31035
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.693369
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00717
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03277
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.01652
HUNS1	DepMap CRISPR Gene Dependency	1.0	2.31261
Intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78845
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.823616
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1563	CCLE Cell Line Gene Expression Profiles	-1.0	-2.41954
GAMG	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.68243
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54066059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07509
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22626
chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94971
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.797146
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1026-SM-4IHKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28273
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.71607
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
BRD-K37515001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22219
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.14357
NCIH1944_LUNG	CCLE Cell Line Proteomics	1.0	3.18172
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901656
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68507
BRD-K50036850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05135
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3303
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72396
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934473
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36025
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2618
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22866
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34918
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09529
Sarcoma_SARC_TCGA-HB-A3L4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20_vs_D1_815_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.89614
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72833997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37612
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56441
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31353
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17095
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31165
Perturb_1138_KO_Ahr_ERP113014	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.48976
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.354
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01623
SKMEL28	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.06783
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21382
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67189
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45624
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46933
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915734
CRCGN015_HEPG2_48H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.40644
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76906
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1594
ALDH1B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00464302
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL1118 (SMC5)	NURSA Protein Complexes	1.0	null
MDST8	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.00256
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00010082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62103
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15761
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97052218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22651
CRCGN009_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18774
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215696
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43832
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41951
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65195
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1352
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5746_NOP14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.736108
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946091
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
DJM-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.2907
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25649458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17294
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.842463
superficial stratum of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08137
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56521
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7501_RPS13_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.740324
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933838
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.9772
ZR751_BREAST	CCLE Cell Line Proteomics	1.0	8.65413
positive regulation of response to dna damage stimulus	GO Biological Process Annotations 2015	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.88379
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.17084
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88888
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50114736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25055
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304214
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23476
GTEX-U3ZN-1926-SM-4DXSG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08956
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11858
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.46485
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20043
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145388
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A375	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.11807
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Smc5-Smc6 complex	GO Cellular Component Annotations 2023	1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0353
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22599787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42646
BRD-K92776249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.967
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24717
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37874
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27610371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28152
EPCAM_OE_GDS4887_343_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cecum adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00728
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
cellular response to dna damage stimulus	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28722
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19857
layer 4 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02764
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.285
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.00215
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06506
PCI4B	DepMap CRISPR Gene Dependency	1.0	2.27075
SIX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K62577212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22431
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20913
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.15304
MX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522881
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873423
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.012
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26596
NDN	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CF-91-JY05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41024
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3157
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92211
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NP3	DepMap CRISPR Gene Dependency	1.0	2.28995
A549_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197774
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59363
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12343
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1718_KO_Ripk3_SRP226420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.15166
KPL1_BREAST	CCLE Cell Line Proteomics	1.0	2.25361
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.2535
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3824
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAGEH1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06306
C3A	CCLE Cell Line Gene Expression Profiles	1.0	1.39591
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03866
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02283
SNUC5	DepMap CRISPR Gene Dependency	1.0	2.25317
AA-86-YY62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233566
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09863466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14699
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29848
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.78844
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.38423
Fetal Death	CTD Gene-Disease Associations	1.0	1.22436
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4974
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5996
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0734
Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09058
BRD-K81082554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30754
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18535662-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00509183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63748
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV_84Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.56276
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11707
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01455
BT20	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45303
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876009
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0605
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548z	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.80026
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3522
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lmo4_17452977_mcf7_lof_human_gpl570_gds2789	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.040645
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46125
16135788-Table24	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8288
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.34756
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09818
Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246660_1_v_0_lmo3_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.062
NCIH1436	CCLE Cell Line Gene CNV Profiles	1.0	1.35605
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67599
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84916
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858985
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00278
BRD-K19320442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1029
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4148-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41404
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73336
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935191
mantle zone of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46346
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.15383
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0771
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65028
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-338-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974748
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
Perturb_173_KD_Asns_SRP119931	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.8404
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
peptidyl-lysine modification	GO Biological Process Annotations 2025	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40097
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMPSTE24_Deficiency_GDS3775_506_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51984
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29224
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932224
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43423
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.21515
medial part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01128
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486854
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6304
NRL_Deficiency_GDS1693_236_mouse_Photoreceptors cells of retinas at P2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K39099034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94982
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_WHI-P154_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144738
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCLC21H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33202
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11232
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KOSC2	DepMap CRISPR Gene Dependency	1.0	2.04481
BRD-K13637593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20449
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	1.10233
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48434
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05755
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41475
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.296
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17074
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.853314
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC3435504-msb201237-s2.xls-Supp_Table_4a-TFDP2_TFDP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39511
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3W-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916529
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04436
glis3_19805515_embryonic_pancreas_lof_mouse_gpl1261_gds3812	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.15205
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45434
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22132
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17458
A549_MC1568_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022425
NFYA	ENCODE Transcription Factor Targets	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47004
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R7-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866054
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.79994
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.926161
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30324
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07539
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.02151
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14595
CAKI1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.993765
BRD-K73039647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20858
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84092
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905127
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CE-95-YX02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.78741
SETDB1	ENCODE Transcription Factor Targets	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5614
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55153
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312802
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSK3A_knockdown_203_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-3.09611
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55235
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.432
BRD-K26809097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72755
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12543
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.649
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.403
FOXA1	ENCODE Transcription Factor Targets	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08236
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.517411
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886015
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08642
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:G18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01768
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13171
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUM-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.43951
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV5-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912605
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45322
BRD-K75380271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13633
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09035
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24433
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.851697
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.45364
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235085
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20325
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.2053
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3025
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448965
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27372
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0945
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35923
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95831
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.661
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2401
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30582
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NC-27-AD53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.908056
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06608
MAGED4	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24433
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0699
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1078_OE_ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71254
BRD-K41809257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23323
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47538
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97682096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68993
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297703
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67304
PMC2742312-1479-7364-3-3-221-S3.PDF-140-EMX2_EMX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83629
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25347
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60691
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.47291
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17387
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01869
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.47763
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14787
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	2.15649
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.743
A549_CYC116_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153869
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE221932,GSE222115_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49644
BRD-K67591072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11508
BRD-K89121101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08035
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56165
GB1	DepMap CRISPR Gene Dependency	1.0	2.03457
BRD-K88720906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23619
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.839219
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31954
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.12892
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
SMC5	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60555
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28912
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964505
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16176
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94775036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27457
BRD-K88936403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.733
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43425
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31465
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Egg chorion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH524	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94654
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T98G	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05792
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12575
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.19878
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	2.00383
Perturb_7542_KD_CTCF_SRP275505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998613
BRD-K37144511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64574
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866321
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.80258
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV_24Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.82562
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70426100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69858
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683724
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969528
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53909
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02116
CHD7	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.94143
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23227
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of DNA metabolic process	GO Biological Process Annotations 2025	1.0	null
Polyomavirus-associated nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00449
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.04465
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54597
Myocardial Infarction_Myocardial tissue_GSE4105	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51708
BRD-K39435284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03313
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406486
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIMT1_BREAST	CCLE Cell Line Proteomics	1.0	2.97114
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09607752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1811
Perturb_9280_KD_DDX24_SRP153815	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61439
IRAK-1-4 Inhibitor I	DeepCoverMOA Drug Mechanisms of Action	1.0	0.46
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7241
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30353
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35043
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07524
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.239
Adipose tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Catecholaminergic polymorphic ventricular tachycardia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10454