association	dataset	threshold value	standardized value
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
BRD-K06685815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15487
BRD-K03467766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0174
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71527
NCIH2126	DepMap CRISPR Gene Dependency	1.0	3.42939
BRD-K19142902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56633
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27612
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.43
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05905
FDX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497616
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OLR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00741311
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61644
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05679
BRD-K51320582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66082
BRD-K16330310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09408
BRD-K81821040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07133
8719_TBC1D3_ENST00000537432.1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.532694
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	150.71
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29305
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
increased circulating alanine transaminase level	IMPC Knockout Mouse Phenotypes	1.0	null
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0412
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07487
LIVF001-012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52594
BRD-K31222955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42687
TINAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07308
BRD-K06002536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2919
HDGFL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00400291
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14349
BRD-K12460934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5645
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.28621
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0052
PMC11459127-pnas.2406837121.sd04.xlsx-Sheet1-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57833824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01127
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plastid envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
BRD-K35001076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10594
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4531
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97122937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01656
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7446
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91866516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37816
BRD-K77535986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76436
BRD-K52532740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69366
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.98073
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.33
PMC10769395-media-8.xlsx-S8E_ETS1_ETS1-ChIP_down-Unnamed_1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45271289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12706
BRD-K64770897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34798
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76114616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36646
BRD-K62698674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01558
HUPT4	DepMap CRISPR Gene Dependency	1.0	4.90798
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.93948
PMC5056720-pone.0164535.s001.xlsx-AR-DE_genes_with_KSC_p-val_05-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CKS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00405586
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09867
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8876
HSC4_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.93955
BRD-K27372445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03466
BRD-K65108634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88135
BRD-K81999794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0681
SFTPD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561123
BRD-K50961262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04856
chr8_123423151_G_A_b38	GTEx eQTL 2025	1.0	3.21326
BRD-K18268126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11927
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4586
NOXO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058041
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31919
2122_DDX46_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510098
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AML-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
BRD-K80336250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46767
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.2566
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75229
BRD-K33151492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05255
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17904
A549_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164497
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1376
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46561246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64008
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	2.07212
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58853
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45055
BRD-K81318113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01299
BRD-K89089981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78986
BRD-K81916372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40472
MEWO_SKIN	CCLE Cell Line Proteomics	1.0	2.65858
LS123	DepMap CRISPR Gene Dependency	1.0	8.55328
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7369
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K85977570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64059
BRD-K76734722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23695
BRD-K40674409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97842
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16319
BRD-K52319351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29724
MB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644205
PMC3371315-NIHMS350140-supplement-12.xls-MCF7-T47D-SK-453_Down_Common_xl-Supplementary_Table_5_Luminal_Signature_Genes_decreased_in_all_four_cell_lines_MCF7_T47D_MB-453_SKBR3_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97470305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29631
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23453
BRD-K66470464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63669
BRD-K02334683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06777
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58674
PMC10859382-41392_2024_1740_MOESM3_ESM.pdf-60-ZNF461_ZNF461	Rummagene Transcription Factor Associations 2026	1.0	null
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07609
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8032
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.74986
ST8SIA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518502
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.5773
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94936556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6615
CRCGN017_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39025
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.88059
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96981233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51721
BRD-K99404845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05515
BRD-K64531863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33494
BRD-K16231990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15876
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1648
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44696459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89336
PMC8052288-mmc4.xlsx-PAF-DREAM-Lung_Poor_Survival-Unnamed_5_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A06149038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02218
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.9418
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57613
BRD-K92356128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82397
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.129
BRD-K34942615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63255
BRD-K63908919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3629
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47724892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6542
BRD-K29366596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16813
chr8_123451843_A_C_b38	GTEx eQTL 2025	1.0	1.14536
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.875
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KIF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27838
BRD-K02802091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00908
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.312
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34666
RPE1SS77	DepMap CRISPR Gene Dependency	1.0	2.54557
Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85456600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10107
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29944
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00795
BRD-K32802965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37345
BRD-K89040444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25201
SCH	DepMap CRISPR Gene Dependency	1.0	2.86615
CSF3R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530118
BRD-K28656917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06978
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35124958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15056
BRD-K44856541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23307
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0217
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ALK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495896
BPH1	DepMap CRISPR Gene Dependency	1.0	2.82981
BRD-K01351858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26049
BRD-K69569958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05077
Intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.236
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K08829593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04048
BRD-K96164740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61413
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
NDUFA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00423491
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OSC19	DepMap CRISPR Gene Dependency	1.0	2.16939
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51524
CYBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490493
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2471
BRD-K39291909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00118
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17314
BRD-K65005022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25118
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44652223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04974
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58756877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91825
BRD-A89237309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75753
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07351191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14024
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K60952519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58105
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64173373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09305
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92825272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19064
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12286
BECKER	DepMap CRISPR Gene Dependency	1.0	4.71938
BRD-K36961619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43743
BRD-K64692525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01231
BRD-K43981353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31309
BRD-K73479560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09173
BRD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00483094
BRD-K54576503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92235
BRD-K58876832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13215
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE184884_6_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86208187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02376
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.44899
BRD-K37625653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30839
BRD-K97348029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00371
BRD-K90571714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6643
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.15797
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.0495
K562_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146169
BRD-K82314391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15389
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.024
BRD-K20798215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36263
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K67905771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44999
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12709183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25523
BRD-K22606370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08345
BRD-K99728124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03182
BRD-K29745629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25345
GSE249544,GSE249637_9_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15643
K562_Entacapone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156524
CRCGN013_HEPG2_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0321
BRD-A16827030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37226
BRD-K52492854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07061
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18128277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11755
TLR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618821
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158347
BRD-K02180800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13288
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8404
Cell septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9124
BRD-K96417480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05744
CRCGN014_HEPG2_3H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00066
APBB1IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633254
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NatA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.49
BRD-K42943023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31353
BRD-K59571728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13361
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.80109
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08126
ADCY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65374
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06801
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80763723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56546
BRD-K70148902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2026
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1284
BRD-K96491664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24632
BRD-K97421379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26471
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26105
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17325
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26166
BRD-K74870161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60716
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC38A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12361
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39501
BRD-K19764912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13212
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.15
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23243
BRD-K33179234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12782
BRD-K38424085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32982
NUDHL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	6.61645
BRD-K65432867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4268
BRD-K53095870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18299
EP300	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511123
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76263570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03578
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.92912
BRD-K00667983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44703
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.606
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.16666
GSE147613_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24387453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00658
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57972271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23699
BRD-K12531686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08704
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14863829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69447
BRD-K73452131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45945
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28236
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61087440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84469
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90447
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77884956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1619
chr8_123447345_C_T_b38	GTEx eQTL 2025	1.0	1.25859
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chloroplast ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.10645
BRD-K84815485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42327
BRD-K58643762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28362
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40424
PMC7356051__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62975
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01971
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K84551755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40161
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4467679-12967_2015_546_MOESM3_ESM.csv--TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02337960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92014
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9522
BRD-K72843176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53834
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
K562_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142992
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6639
BRD-K97595801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72416
BRD-K70721203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41746
BRD-K02946901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02331
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
TIPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574552
BRD-K57045425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07294
BRD-K14534138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2863
FHF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.686
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18714
EVSAT	DepMap CRISPR Gene Dependency	1.0	3.35822
OCIMY5	DepMap CRISPR Gene Dependency	1.0	3.17324
BRD-K22683888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36682
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39925250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.157
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11396
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0493
BRD-K57404319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51473
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5354
BRD-K32759631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14186
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20668
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76166595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02387
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.633645
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lufenuron	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0776
BRD-K46322281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18443
BRD-A07952294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09695
BRD-K07836769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72743
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41004
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K60862683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04692
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18378
CRCGN011_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06385
10478_ZNF585A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.67026
BRD-K92544320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20586
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.43044
A549_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176094
PCI15A	DepMap CRISPR Gene Dependency	1.0	4.96893
PMC9314667-Table_1.xlsx-Regulons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45959036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67716
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NRG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00911737
BRD-K40724407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07315
BRD-K88179337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19345
BRD-K32082369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32357
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34259
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190384,GSE190386_3_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K52833964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34524
BRD-K86159732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40917
MCF7_Fedratinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0105939
BRD-K78818514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34361
BRD-K82805160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47971
BRD-K82284644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06814
BRD-K50604515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72304
CRCGN015_MCF10A_48H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33645
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
1165_CAMKK2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.53283
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53151
BRD-K97562463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72803
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68162101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34007
nucleus	GO Cellular Component Annotations 2025	1.0	null
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25073
BRD-K62853937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18544
BRD-K86986621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30968
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.776624
SELPLG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488584
BRD-K73459389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96209
BRD-K11674021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13272
BRD-K80895505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1322
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1973
HEYA8	DepMap CRISPR Gene Dependency	1.0	2.03115
BRD-K90962922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4897
BRD-K38617061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90077
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1942
DB	DepMap CRISPR Gene Dependency	1.0	2.24686
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21995
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6775
BRD-K77108448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18386
BRD-K87930002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20667
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
RAJI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18703
BRD-K41241300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06824
BRD-K01960204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17441
BRD-K73841784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51847
BRD-K25645002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41638
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92565319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64038
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5977
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00364932
BRD-K09168812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70666
GSE128076_2_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12431811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05209
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.624
BRD-K63383299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0649
BRD-K01266518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02322
BRD-K92212152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57602
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04156
PTK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00329472
BRD-K02548315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93116
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6711
7607_RUVBL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.52296
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5768
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7916
HT115_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	6.32226
BRD-K46805838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0731
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.4272
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24171
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr8_123450077_T_C_b38	GTEx eQTL 2025	1.0	2.03964
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7302877-elife-57679-supp3.xls-HuRI_ZNF165_interactors-Gene_Name_ZNF165	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Tranylcypromine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146081
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7373
BRD-K68060538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22576
BRD-K94273044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4506
TUBA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00782446
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Unnamed_4_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
ATXN7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79699
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20184
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25991
CRCGN015_MCF10A.WT.HP_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05755
GaMG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
BRD-A90462498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06692
BRD-K28139946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13779
BRD-K08174111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27041
BRD-K70530990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07116
BRD-K70289438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18119
BRD-K39546571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44777
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74173779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32765
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.236
Proteasome storage granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
SLC39A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0068506
YD8	DepMap CRISPR Gene Dependency	1.0	9.53825
BRD-K31720099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94185
BRD-K23956364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31526
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11373733-ABR-13-34_Suppl1.pdf-227-ZBTB9_ZBTB9	Rummagene Transcription Factor Associations 2026	1.0	null
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K59522787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3314
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_up-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38343532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17814
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_PD98059_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122967
K562_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152683
Protein storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
BRD-K39223685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17745
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50941200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10037
BRD-K11782435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00595
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UFSP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560951
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76698
MCF7_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123651
CRCGN015_MCF10A.WT.HP_24H:M18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06091
BRD-K36643302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78041
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
BHT101	DepMap CRISPR Gene Dependency	1.0	5.94182
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31538
BRD-K40760168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69132
BRD-K60543885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04032
BRD-K92712225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1554
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29707
SAP30	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585357
BRD-K11297155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47929
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Divalproex Sodium_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118043
pridinol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41513
BRD-K61027868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12517
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59644
BRD-K31479652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43329
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38729
Hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1009
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2093
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45193
BRD-K45348630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17187
GSE214823,GSE214824_0_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36382446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7768
BRD-K67572910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77593
PRPS1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617345
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.618864
MCF7_Divalproex Sodium_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139656
SCN4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552385
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5082
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87465930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42143
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
RIOK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00666313
BRD-K97537859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00276
MYO9B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605475
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061302
1535_CFH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.571276
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37506332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05284
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1338
macromolecule modification	GO Biological Process Annotations 2023	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154307
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thyroid follicular epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
BRD-K12376164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46201
BRD-A50837272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27929
BRD-K81131499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48925
BRD-K47164766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06007
BRD-K59006776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09707
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2653
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86605
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.668
BRD-K23299829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11079
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22875065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23335
BRD-K40804250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13307
SKBR3	DepMap CRISPR Gene Dependency	1.0	6.00034
BRD-K26941844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79338
BRD-K73775927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68037
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0556
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4461
BRD-K92524632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55013
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MYCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0346
BRD-K60850201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43891
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32958
TMPRSS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605952
BRD-K89805365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49961
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.597
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00062
SIRPG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689748
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
BRD-A89471191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17939
MCF7_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136745
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4054
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65959331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12147
PMC10769395-media-8.xlsx-S8G_ETS1_ETS1_bound_siFLI1_down-Unnamed_6_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01279
BRD-K55853030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6573
BRD-K70042405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00374
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159815
BRD-K70717477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06708
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46137
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4516
PLEKHJ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00391996
CRCGN008_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1356
8305C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5232
decreased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUBGCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17338
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06519744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08131
NatB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.881
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83371
PLS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640371
BRD-K09100418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08997
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47878187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3635
BRD-K27476515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92278
BRD-K69154646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83016
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6623
BRD-K36848506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61406
BRD-K64567246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33267
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0193
BRD-K57969360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44617
BRD-K87268607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41367
macromolecule modification	GO Biological Process Annotations 2025	1.0	null
BRD-K98941192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62409
K562_BMS-265246_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140542
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	166.807
BRD-K95485901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90144
PMC12164972-FSB2-39-e70689-s001.pdf-2-LOC105369212_NR2F2-AS1_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38970027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99706
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.708
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
chr8_123440963_C_T_b38	GTEx eQTL 2025	1.0	2.92761
sbc7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.419
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1229
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.94213
BRD-K39476596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07544
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
L-428 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23611
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.91683
BRD-K88590066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07905
VCP-NPL4-UFD1 AAA ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
BRD-K11003742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59534
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67164
BRD-K80803211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97766
TAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570931
BRD-K77324165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41502
MCF7_Raltitrexed_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115406
BRD-K06439119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10283
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8667
BRD-K78907463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56327
chr8_123425560_G_A_b38	GTEx eQTL 2025	1.0	2.50283
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28111
Storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76885311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93896
Cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.315
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1038
BRD-K44027058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11767
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1112
FADU	DepMap CRISPR Gene Dependency	1.0	2.3628
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.717
PCDHB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19599
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30305
BRD-K52428486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0642
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15876355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12983
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16879
PMC9314667-Table_1.xlsx-Regulons-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5682
GSE206729_3_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71177762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20963
BRD-K31844308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32133
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.744
PMC6433297-pbio.3000178.s012.xlsx-DREAM_targets-BUB1B_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.236
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6286
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05262
BRD-K85901675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45902
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.336
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A61778798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05899
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3547
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22921
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77548697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02751
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22043
BRD-K58932103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22367
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-461-ZBTB46_ZBTB46	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169848
BRD-K49207204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05448
BRD-K03194507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16957
BRD-K58242935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29196
GSE118532_0_v_1_rnf168_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chr8_123417155_A_G_b38	GTEx eQTL 2025	1.0	6.18808
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30812
PMC10274745-media-4.xlsx-S3A-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54138
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68313
chr8_123463387_G_C_b38	GTEx eQTL 2025	1.0	1.39556
BRD-K83569804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08953
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.632
protein modification process	GO Biological Process Annotations 2023	1.0	null
BRD-K42457027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48826
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16502264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95535
BRD-K49409924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66784
BRD-K92484282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01573
BRD-K88820027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50328
BRD-K33503286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2918
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.23446
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7523
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43175
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06105
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4707
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46641
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AMHR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537054
BRD-K94082609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24426
CRCGN015_MCF10A.WT.HP_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36268
BRD-K31678817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20781
BRD-K16888026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04243
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77417197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04357
BRD-A63704386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1227
BRD-K48102350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85542
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10539
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.52022
MOLM14	DepMap CRISPR Gene Dependency	1.0	2.79031
BRD-K56783915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.74384
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12372887-sciadv.adx2434_sm.pdf-55-HHEX_HHEX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88941096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17587
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.236
CRCGN015_HEPG2_48H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18839
BRD-K96258717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72692
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07388
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.6705
BRD-K76350099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4184
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183996
BRD-K87593103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31369
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
skein-like inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0181
BRD-A59391763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39741
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr8_123439435_C_T_b38	GTEx eQTL 2025	1.0	6.51912
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.61
BRD-K27838482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36916
CRCGN017_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.977
GSE218171_1_v_0_foxn3_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr8_123442830_A_G_b38	GTEx eQTL 2025	1.0	1.06592
BRD-A09961470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40457
MCF7_EED226_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139966
K562_WP1066_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156758
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017016
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0988
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	2.00599
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35108166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15618
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29615
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL62	DepMap CRISPR Gene Dependency	1.0	2.96102
BRD-K82930531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23801
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33277
BRD-K53508363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95522
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2046
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32916996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19401
BRD-K16518464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73492
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0042
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45112
DOK	DepMap CRISPR Gene Dependency	1.0	2.842
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31759
Chloroplast thylakoid membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48188521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29213
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.335
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.11945
BRD-K86587289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10056
GSE223334_1_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7521
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0435
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.525086
CRCGN015_MCF10A_48H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09966
BRD-K02403042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48294
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.721
BRD-K95213130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17976
BRD-K43926323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16616
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48604
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30664
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36722
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	188.945
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
USP19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00416881
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52492
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2077
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4474
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8232
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94582694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22793
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.247
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24636
BRD-K31393518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04809
BRD-K43295075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54524
BRD-K71460915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42871
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06901
ES8	DepMap CRISPR Gene Dependency	1.0	2.23831
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26879
CRCGN013_HEPG2_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5975
CRCGN011_HEPG2_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05475
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38245
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52972
BRD-K93534327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28319
BRD-K70886325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47794
CRCGN012_HEPG2_24H:P07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02942
Glycoprotein network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
BRD-K14732815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31789
PMC10769395-media-8.xlsx-S8G_ETS1_ETS1_bound_siFLI1_down-Unnamed_11_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11116544-41698_2024_606_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_4_Significantly_differentially_expressed_genes_between_TCGA-HNSC_patients_carrying_amplified_MYC_and_wild-type_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11781871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50817
BRD-K72651085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23628
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47085
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.299
BRD-K01577807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11461
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0082059
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4367
BRD-K76738405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56218
BRD-K87853964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8987
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH441	DepMap CRISPR Gene Dependency	1.0	15.3578
BRD-K20331065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25318
BRD-K17514980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17592
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
BRD-K30964167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4543
BRD-K39752756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35893
BRD-A84867566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10928
PLCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504611
OCUM1_STOMACH	CCLE Cell Line Proteomics	1.0	6.54036
BRD-K42232544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21864
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
3336_GEMIN5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.655492
D283MED	DepMap CRISPR Gene Dependency	1.0	2.91032
GSE146687_2_v_1_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K75649446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01838
PMC12397405-42003_2025_8738_MOESM4_ESM.xlsx-Supplementary_Data_5-MR_Exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.72522
BRD-K22471908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75538
BRD-K41396351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69893
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K71251432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06377
NCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79733
GSE211286_4_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53936012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6007
K562_Altretamine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014813
BRD-K44684577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72178
chr8_123418223_G_A_b38	GTEx eQTL 2025	1.0	1.99727
PMC12211054-spectrum.00100-25-s0002.pdf-69-NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5488
PMC6377303-NIHMS1504983-supplement-2.xlsx-AR_signature-To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
F36P	DepMap CRISPR Gene Dependency	1.0	2.07056
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03746
BRD-K58208155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84844
CHRNA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557742
BRD-K47108422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40088
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.367
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132657
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5533
BRD-K52876244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21576
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A92490200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12289
PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
chr8_123424174_G_T_b38	GTEx eQTL 2025	1.0	1.25183
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBR1-RAD6 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.405
MCF7_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115212
PIP4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04782
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7814
USF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12627
BRD-K85271599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24756
PMC10769395-media-8.xlsx-S8G_ETS1_ETS1_bound_siFLI1_down-Unnamed_1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94962552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51392
BRD-K03851221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09803
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.243
chr8_123460842_G_T_b38	GTEx eQTL 2025	1.0	1.68678
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5599
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85362541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44322
MAP3K2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00658867
4148_INTS3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.549079
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71594
Chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.367
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3168
BRD-K39815998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41465
PMC11955568-41467_2025_57429_MOESM9_ESM.xlsx-Data_S7-CEBPB_OEKO_Huggins2013_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68134791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07891
MOLT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35462157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63698
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51358
BRD-K23617623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30984
BRD-K69922285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2299
BRD-K75821161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64174
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11966
BRD-K81647747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07477
7979_SLC22A23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.599178
SLC25A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557385
BRD-K78363521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04389
BRD-A73559168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87636
CRCGN015_MCF10A.TP53.M_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31039
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52859120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38627
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.76204
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.716
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cystocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCILY19	DepMap CRISPR Gene Dependency	1.0	9.53586
GSE126219_0_v_1_haloperidol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.22292
BRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613717
BRD-K34425773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14382
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.174
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28919392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59781
ITGAV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00446413
BRD-K59535072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47517
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K09842906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64532
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1592
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.091
BRD-A84913188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3063
BRD-K54453373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16535
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8895
MCF7_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183459
Apical hook	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
BRD-K34414758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07911
BRD-K07861364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30317
BRD-K41700289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79223
BRD-K24700188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12404
PDXP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525467
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.57585
BRD-K71574401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80943
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K00411149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36962
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76215709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07122
BRD-K13113551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48775
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55332
BRD-K00378498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48727
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.89295
BRD-K71644199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41582
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OAS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664573
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	186.909
CRCGN015_MCF10A_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5382
TNFRSF10D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561997
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02652
SLC29A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056671
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43069
LK2_LUNG	CCLE Cell Line Proteomics	1.0	5.34871
monolayer-surrounded lipid storage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03057797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6929
BRD-K11844860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41368
BRD-K67980010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00639
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8119
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8573
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.800247
GSE190384,GSE190386_2_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69705285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05998
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02837259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22495
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81465091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78733
BRD-K61698250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87845
BRD-K83697352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67326
STK19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554658
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.25102
PIP5KL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006305
BRD-K39328339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36003
NPHP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513986
BRD-K24337237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2892
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94071
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2443
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.91651
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2566
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07336866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73173
BRD-K98535708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7897
BRD-K03089783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21448
BRD-K58892587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29227
BRD-K47821225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34916
CRCGN011_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41175
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41024
BRD-K71247208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19314
BRD-K75224334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08324
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46496
BRD-K86104966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21721
BRD-K46400317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15813
BRD-K21327356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38728
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8137
BRD-K15099225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38291
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72549552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76737
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051231
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59118
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82052
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.9028
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10486
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1269
BRD-K91011325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44416
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
protein modification process	GO Biological Process Annotations 2025	1.0	null
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22026
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7579
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4644
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55277
BRD-K45472595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47047
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27092
BRD-K78493876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08291
SKN3	DepMap CRISPR Gene Dependency	1.0	2.09275
KLF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21275
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CETP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.008202
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8477
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71674
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27759
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13785
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35691
chr8_123463782_A_G_b38	GTEx eQTL 2025	1.0	1.23431
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1196
BRD-K45134469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21191
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124782
GSE210662_2_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70684
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136465
BRD-K28619632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34022
BRD-K16670438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02011
BRD-K28349636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44798
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13756
BRD-K87982677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72469
BRD-K86073842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21321
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05517
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42855618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12671
BRD-K74040368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67579
BRD-K12867546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03275
YY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517368
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00895
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Appendicular lean mass	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.23979
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0471
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.8355
BRD-K17895004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29722
BRD-K27671601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3728
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
BRD-K24385654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49702
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.503227
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.5944
BRD-K85554193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24989
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K56086519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26081
BRD-K27092365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68348
GSE127916_1_v_3_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K89364982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1903
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr8_123426642_G_C_b38	GTEx eQTL 2025	1.0	5.99589
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.361
BRD-K91897530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81713
PMC7672319-mmc3.xlsx-DREAM_MSigDB62-FISCHER_DREAM_TARGETS_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79347397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61694
HSF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514497
increased leukocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K71758378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09309
BRD-K42016545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15881
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03276
BRD-K84606053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61414
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160001,GSE160670_1_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_GSK-LSD1 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135745
A549_AG-490_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129726
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18468
BRD-K95048194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82147
BRD-K17040651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3417
BRD-K83898111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14811
Metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
decreased mean corpuscular volume	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.08026
BRD-K71521842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28396
BRD-K07624584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90352
PARG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677926
decreased mean corpuscular hemoglobin	IMPC Knockout Mouse Phenotypes	1.0	null
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3527701__F2	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.24272
BRD-K83115645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09054
PMC10769395-media-8.xlsx-S8E_ETS1_ETS1-ChIP_down-Unnamed_6_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01751
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2424
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16931
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1069
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A81260764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35803
HSPA1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00700112
BRD-K99331577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26619
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36317
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193993_4_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77697725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12358
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.236
BRD-K36104357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76544
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150673
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9574
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
chr8_123422545_G_A_b38	GTEx eQTL 2025	1.0	1.17442
SNUC5_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.05424
BRD-K66605600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0031
GSE161170,GSE161268_0_v_2_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68547601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45867
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59523233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76291
PADI6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048506
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1103
BRD-K09721867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43203
TPRKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00376266
BRD-K80424876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51315
BRD-K29143088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03117
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.63772
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42529194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26481
BRD-K98880643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02956
BRD-K97934318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17679
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02312
8218_SNRNP27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.537227
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14359826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32627
KURAMOCHI_OVARY	CCLE Cell Line Proteomics	1.0	2.0849
BRD-K67666705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18172
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYT11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053154
BRD-K25408656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08223
GSE214823,GSE214824_6_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A26640795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16208
BRD-K87044635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09722
VEGFC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507197
BRD-K56650430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36159
PMC8346999__F1	PFOCR Pathway Figure Associations 2024	1.0	null
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09695
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57272
BRD-K04036799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4453
BRD-K70941721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24054
BRD-K15775306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28425
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4264
BRD-K01166365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25911
SLC22A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00402988
BRD-K24838542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03259
BRD-K33037101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29886
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29086754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07497
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
3570_GTF2E2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510624
BRD-K92433763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24876
BRD-K97485863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02863
BRD-K03440991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14591
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56055
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S6-Synteny-Syntenic_Analysis_for_29_HSF1-CanSig_8q_Genes_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37517
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36225
PMC8494348-pone.0257161.s002.xlsx-D20-OXT_ext_D20-OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
NatC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.391
PRRG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00797543
GSE223008_9_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34875
BRD-K38980456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11665
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88924
BRD-K75243062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04188
chr8_123448513_T_A_b38	GTEx eQTL 2025	1.0	3.55107
BRD-K81619018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48477
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.37441
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0313
BRD-K46985581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05932
BRD-K64066545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23354
BRD-K27645251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32161
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1793
BRD-K44956383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84456
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28194
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Regorafenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143182
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6384
BRD-K32925057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77097
GSE193258,GSE193259_9_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A46317335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00766
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02152
BRD-K72317601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23169
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
GSE173307,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K25649596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50658
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7902
BRD-K60454544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03302
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17039
BRD-K34721572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59892
BRD-K96958073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25858
CRCGN015_MCF10A_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28577
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09328
Cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07308
PHOSPHO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551899
BRD-K26423054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3779
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51635
MAX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00872172
impaired pupillary reflex	IMPC Knockout Mouse Phenotypes	1.0	null
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60291
A549_TMP195_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185879
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.9879
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14522
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11651170-pt4c00533_si_002.pdf-70-ZNF490_ZNF490	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98538
BRD-K94014790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54097
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K56943789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04891
BRD-K58220566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37207
DMRTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28312
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.92541
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33891642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07335
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11517
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.47155
L3MBTL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636265
BRD-K19378563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60702
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.28679
6795_PRPF38B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.528432
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01644
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76924
PMC10769395-media-8.xlsx-S8E_ETS1_ETS1-ChIP_down-Ebegboni_et_al_Supplemental_Table_S8E_Genes_decreased_following_the_ectopic_expression_of_ETS1_and_bound_by_ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29082
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.586
GSE190384,GSE190386_1_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60781525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49536
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01256
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.644117
BRD-K87412446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1977
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4324
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9326
BRD-K95854766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02362
BRD-K71801719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3087
BRD-K07361992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31859
chr8_123432512_G_A_b38	GTEx eQTL 2025	1.0	6.10971
BRD-K54250149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50948
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21743
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5892724-fj.201700693R.st1.xlsx-si-CLOCK_vs_scrambled__ZT44-Unnamed_1_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11708
chr8_123442726_C_T_b38	GTEx eQTL 2025	1.0	1.05057
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12731
BRD-K15282657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46411
GSE146070_1_v_0_edem3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99638698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68082
BRD-K12397820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26139
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.739502
PIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517033
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-DREAM_target_genes_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97393725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8947
chr8_123425775_C_T_b38	GTEx eQTL 2025	1.0	2.69407
BRD-K76389813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40283
K562_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147362
10442_ZNF554_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.622107
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7160301-Data_Sheet_1.xlsx-Sup_Table_9-Not_interacting_with_APP_or_NRF1_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7824
BRD-K85823016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07487
BRD-K76450447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04821
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76976010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26095
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79299080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32685
BRD-K36134264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45633
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73830970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03558
decreased mean corpuscular volume	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K59272984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09049
BRD-K76812105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12489
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04046
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08281
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
chr8_123442339_C_T_b38	GTEx eQTL 2025	1.0	1.55661
BRD-K52551495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94664
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61021741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64516
BRD-K04192407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10344
BRD-K75915595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24467
CRCGN008_HEPG2_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06055
BRD-K22173206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58823
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50389
GSE190384,GSE190386_6_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24622
ESR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05489
CHRND	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00629983
BRD-K95651150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43107
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39338
AXIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504804
CRCGN011_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1323
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56283394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85212
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55043
BRD-K59913416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37914
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
increased leukocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
impaired pupillary reflex	MGI Mouse Phenotype Associations 2023	1.0	null
PMC11699013-12672_2024_1699_MOESM1_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_The_association_between_proteins_and_CLL_in_the_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18211442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30208
BRD-K10221669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00268
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
RKO_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.92371
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3371
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65969
BRD-K25328765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09275
BRD-K68379391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05967
abnormal behavior	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K19573822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69756
BRD-K02625776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76961
BRD-K61821542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17271
BRD-K66762690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53211
CRCGN016_MCF10A.TP53.M_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11865
increased circulating alanine transaminase level	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K87532481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1264
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46433
BRD-K24977393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82011
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61943321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2683
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6544
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35635
BRD-K59046641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0218
IL12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00670737
BRD-K26866198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27621
BRD-K62372121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76657
BRD-A94740628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19724
BRD-K96623405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27819
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99942
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.82998
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2289
BRD-K02050740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3259
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.2485
BRD-K78902613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17566
chr8_123435948_G_A_b38	GTEx eQTL 2025	1.0	2.4762
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A59009217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48383
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4205
BRD-K14589361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26902
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75232
BRD-K79997957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36671
BRD-K06678077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28809
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14394756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18357
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35625946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04477
BRD-K65184008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42675
BRD-K25933460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22421
BRD-K71138333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19494
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02393180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06067
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6819
BRD-K93503664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79439
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37595074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15614
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3068
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75220555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17066
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3493
NDFIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0031953
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29395
BRD-K54370483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13973
MCF7_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139145
BRD-K77869482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19345
BRD-K67563379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06152
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
B3GNT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619785
BRD-K28165728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41286
BRD-K37398853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25479
PPARD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00339857
BRD-K99452971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85914
BRD-K86232678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14442
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAOV4	DepMap CRISPR Gene Dependency	1.0	4.53404
BRD-K91225366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73467
BRD-K92344227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07201
BRD-K18031793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11028
PMC12769604-13402_2025_1147_MOESM6_ESM.xlsx-Table_S4_3_Venn-Tumor_AND_Prognosis_NOT_Scissor_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12260399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59222
TBX2-35687133-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K63960902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34602
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14417813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11771
GSE120336_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79887921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71259
BRD-K53971345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18344
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6455_PLK4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.54697
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21108
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22219
decreased mean corpuscular hemoglobin	MGI Mouse Phenotype Associations 2023	1.0	null
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36607
BRD-K41829399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99855
BRD-K59957885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12385
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78697404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17606
HCC366	DepMap CRISPR Gene Dependency	1.0	2.36038
PMC10534007-Table_2.xlsx-S1_overlap_MSC_up_B_V-438_common_elements_in_BFTC905_MSC_up_and_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
B4GALT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548312
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84306
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86546
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86964464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05247
BRD-K57516590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26372
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0205181
BRD-K91399333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13301
BRD-K38955287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30607
OXER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647124
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96605
BRD-K95171874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54175
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.796
BRD-K35963610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47458
Hepatoma HLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.819
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.41437
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50528
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4484
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7302877-elife-57679-supp3.xls-HuRI_ZNF165_interactors-Ensembl_ID_ZNF165	Rummagene Transcription Factor Associations 2026	1.0	null
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08022
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.89425
BRD-K37956279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97444
nucleus	GO Cellular Component Annotations 2023	1.0	null
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09012
BRD-K61796560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37629
BRD-K98601267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07481
PMC12754461-ab-25-0268-Supplementary-3.pdf-21-SOX13_SOX13	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MUC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496209
chr8_123440463_G_A_b38	GTEx eQTL 2025	1.0	1.30317
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10689
BRD-K02361314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58729
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9548
A549_Filgotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122498
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03305
SNU1327	DepMap CRISPR Gene Dependency	1.0	7.30984
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.74409