association	dataset	threshold value	standardized value
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
la4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
Neuropsychological Tests	HuGE Navigator Gene-Phenotype Associations	1.0	null
sensory perception	GO Biological Process Annotations 2015	1.0	null
SW982	DepMap CRISPR Gene Dependency	1.0	3.30224
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15681
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0806
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55847
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BB65-RCC	GDSC Cell Line Gene Expression Profiles	1.0	2.49121
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23162
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77433
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50364
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34657
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33538
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27015
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3948
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL-41 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
CRCGN016_MCF10A.WT.HP_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13406
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07219
SKMM2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29855
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46923
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKLMS1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.53877
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
BRD-K98451611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87979
Venom gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
MM160113	DepMap CRISPR Gene Dependency	1.0	4.37326
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.643009
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sm-like protein family complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.765
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
NEUROTENSIN	DGIdb Drug Targets 2026	1.0	3.78086
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859539
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.90526
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6906
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914626
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1434
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60867
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40584
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849997
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.122157
GSE203131_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
BRD-K60161601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02487
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	1.56517
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93943
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829619
BHLHE23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35739
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17753
BRD-K44139682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30032
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.64367
NANOG	ENCODE Transcription Factor Targets	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87614
HMGN3	ENCODE Transcription Factor Targets	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17709
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25859
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K64474460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47119
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
Small intestine mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07117
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888374
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81949
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41033271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67435
BRD-K57969466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32508
PMC5434854__F2	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K37062347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30798
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73135
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06838
GATA2_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20376
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65616
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12125
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.985
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
BRD-K45282766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16709
JMV457	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BRD-K37510443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29456
GSE207914_2_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42971210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24477
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.93311
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37902
OS252	DepMap CRISPR Gene Dependency	1.0	2.81955
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17179
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14455
MYOG	ENCODE Transcription Factor Targets	1.0	null
Diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.925
TP53	ChEA Transcription Factor Targets	1.0	null
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.284
Perturb_14003_OE_Kcna2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15473
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13044
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935866
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	212.0
ERBB2_druginhibition_6_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.02585
PHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03024
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175188
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21732
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91433
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
BRD-K09596790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06791
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.51506
ZNF655	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68124
TIA1_KO_GSE54418_267_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21205
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_16507_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K12347309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27764
abnormal prepulse inhibition	MPO Gene-Phenotype Associations	1.0	null
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934593
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A	ChEA Transcription Factor Targets	1.0	null
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10806
OVCA420	DepMap CRISPR Gene Dependency	1.0	5.54314
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4436
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.06044
NFKB1_01_167	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60378
REST	ChEA Transcription Factor Targets	1.0	null
POLR3A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.59155
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.553286
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.54325
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81493
Superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25493
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18297
Dot1l_DELETION_GDS4295_426_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 3 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01954
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38123
Signaling by GPCR	Reactome Pathways 2014	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3069
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04284
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Senescence_frontal cortex_GSE1572	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.63301
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.180339
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921663
Thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	0.974052
Levocabastine	DrugBank Drug Targets	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4274
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76903
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27591
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.583397
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49761
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895355
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856106
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95734
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05236
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.178563
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52694
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07422
Perturb_14988_KO_Phf8_SRP093797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.63918
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96876
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34253
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36167
r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00999
receptor activity	GO Molecular Function Annotations 2015	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.14865
BRD-K21412601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37407
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82198
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
NUAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24952
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964836
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5078
Fibrolamellar carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTB_KO_GDS5089_486_mouse_Cerebellum and granule neurons	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235748
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07598
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19757
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.11429
ZNF160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13897
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.253291
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.529113
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.067
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65860773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19863
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52801
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97138361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1434
BRD-K31758107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20526
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17148
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32679
BRD-K45498945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95762
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865152
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44582497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52025
BRD-K36314834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4036
BRD-K63587749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50832
Disease Models, Animal	HuGE Navigator Gene-Phenotype Associations	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41147
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69445
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96452
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63357
HSD11B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2762
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16879
PMC6938365-pone.0226733.s018.txt--ZNF217_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98395
Paraventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7983
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22124
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00486
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01747
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75965
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0952
BACH1	ChEA Transcription Factor Targets	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14964
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9868
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2212
ARID3A	ENCODE Transcription Factor Targets	1.0	null
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03824
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H358 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328994
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41535
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ACHE_OE_GDS891_241_mouse_Prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957909
BRD-K23591737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09892
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58685
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4499
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08201
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.74263
TC138	DepMap CRISPR Gene Dependency	1.0	2.21148
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03777
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33262
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15869
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849762
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27266
PMC4496795-srep12063-s2.xls-STAT1_subnetwork-Gene_symbol_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35306
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55682
NCIH28	CCLE Cell Line Gene Expression Profiles	1.0	1.70432
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7007
CRCGN017_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79728
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48991
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2075
BRD-K59843356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18994
BRD-K06614664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62858
G alpha (q) signalling events	Reactome Pathways 2014	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51331
Perturb_1112_KO_Vcan_SRP167386	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.56426
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.985
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33068
L33	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07842
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
SKCO1	Achilles Cell Line Gene Essentiality Profiles	1.0	2.03747
BRD-K96945247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21781
BRD-K23430426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16992
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.45554
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271952
BRD-K18515345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23161
Brain Lower Grade Glioma_LGG_TCGA-HT-A614-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82039
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33701
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88017
PANC1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15613
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75897
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862886
Luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
Nigrostriatal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14958
NOS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.61764
SW620	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69719
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ethinyl estradiol_oryzias latipes_gpl16266_gse44859	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16508_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrin-CREB signalling pathway via PKC and MAPK	Reactome Pathways 2014	1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12648
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.20814
BRD-K91241684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06067
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
membrane	Phosphosite Textmining Biological Term Annotations	1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
Infantile neuronal ceroid lipofuscinosis_Brain_GSE6678	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49928
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
Kidney Chromophobe_KICH_TCGA-KM-8441-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00844
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27816
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	151.595
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54317642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00758
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.869916
BRD-K31024887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41987
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834879
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8054
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22418
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
SF295	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74668
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20470077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9688
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANPR-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.42
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
Spliceosomal snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.878
BRD-K68890376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86893
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05301
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11162
UT7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7089
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0239
Neostriatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
BRD-K38932508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10886
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2357
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8560_KO_Kpna1_SRP124160	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.73104
BRD-K68705041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16661
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70183558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80351
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41535
BRD-K86593041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11916
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.629506
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02901
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3299
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11193
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3104
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02266
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35699
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76462
Spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.037
COMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.48794
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19516
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Presynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
neurotensin NT79	CTD Gene-Chemical Interactions	1.0	null
BRD-K83459401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35119
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057482
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041741
Sleeping sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32949
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98452
Spinocerebellar ataxia type 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
NCIH1573	CCLE Cell Line Gene Expression Profiles	1.0	1.70142
pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110523
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82746
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04966
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
KNS42	DepMap CRISPR Gene Dependency	1.0	2.73317
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64206
BRD-A32018906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27942
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72448
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40896
DUS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52379
BRD-K13074426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65604
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased	GeneRIF Biological Term Annotations	1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Raji	GDSC Cell Line Gene Expression Profiles	1.0	1.80119
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33538
determined	GeneRIF Biological Term Annotations	1.0	null
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50492
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
SLC12A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82785
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K68495784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76629
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055225
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.25291
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
LEVOCABASTINE	DGIdb Drug Targets 2026	1.0	3.78086
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96659
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1726
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870326
Pancreatic adenocarcinoma_PAAD_TCGA-RB-A7B8-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06142
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K90594901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20064
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11768
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thr<sup>10</sup>contulakin-G	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BRD-K35852282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01853
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
hsa-miR-4733-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
USF1	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.495
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78763
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.828
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02021
GATA2	ENCODE Transcription Factor Targets	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34835
BRD-K65969715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29748
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05406
G protein-coupled neurotensin receptor activity	GO Molecular Function Annotations 2023	1.0	null
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47337
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29735
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29615
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
SBC5	CCLE Cell Line Gene CNV Profiles	1.0	1.39953
BRD-K63912037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67867
ATF2	ENCODE Transcription Factor Targets	1.0	null
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	Reactome Pathways 2014	1.0	null
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33349
SUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50538
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.005516
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01831
Neuroactive ligand-receptor interaction	KEGG Pathways 2026	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87341
PMC6823153-NIHMS1535502-supplement-3.xlsx-LSD1_SupplData1-Supplementary_Data_1_Potential_common_target_genes_of_LSD1_and_GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1178	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060399
BDP1	ENCODE Transcription Factor Targets	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11818
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17148
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14292
LC-1-SQ	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
Neurotensin type 2 receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.829637
NR2F2	ENCODE Transcription Factor Targets	1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1119
aromatic	GeneRIF Biological Term Annotations	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059995
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3077
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05445
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82707
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947072
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04243
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3146_KO_Mrfta/Mrtfb/Myocd_SRP388810	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.89941
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13478
extracellular	GeneRIF Biological Term Annotations	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CFPAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.57111
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2891
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36308
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42385
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.923745
leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181111
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09154
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15869
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	1.40163
PHF8	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04284
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081603
Catalytic step 1 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.1
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.750405
hsa-miR-922	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K30013099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03703
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K15602285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95739
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.457
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.87159
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SKNBE2	CCLE Cell Line Gene CNV Profiles	1.0	1.42398
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04635
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25597
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08143
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880565
AML-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12375
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01251
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30678
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04242
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10447
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919685
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041629
BRD-K69903018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22241
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915904
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89705
ZSCAN26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10153
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.72866
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30234
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63495
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11003
astroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083047
normal	GeneRIF Biological Term Annotations	1.0	null
BRD-K58963469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10072
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46126513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0747
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516104
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K35128023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26811
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10715
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11626
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27531
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8655
BRD-K38737333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18042
Perturb_12086_OE_Esr1_SRP050547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.89893
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0873
BRD-K71561082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07734
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38934
protein-transport	Phosphosite Textmining Biological Term Annotations	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.266
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36828
REST_01_211	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.14329
BRD-K39081386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18498
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.242
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.57776
BRD-K09405682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05865
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86097
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40630587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68522
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2058
PPRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68047
OUMS23	DepMap CRISPR Gene Dependency	1.0	3.55402
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972302
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AC-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01187
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.28731
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37671
Nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
BRD-K89820077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3404
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07313
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11125
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.8
647V	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
BRD-K88395026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08674
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42926
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865388
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10293
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31332
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43223
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K11630986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04178
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13912
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06732
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0476
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
KYSE510	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.99092
overexpressed	GeneRIF Biological Term Annotations	1.0	null
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
BRD-K26758344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37789
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05631
H3K27me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neuroendocrine tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
BL2032 (RFWD2)	NURSA Protein Complexes	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41857
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964779
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93543
BRD-K52340217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5281
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067544
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35552
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.587054
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33875
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31332
CHD1	ENCODE Transcription Factor Targets	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	3.52572
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
Perturb_4721_KO_Setd5_SRP117752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.6737
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271952
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15759
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.662
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.985
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32706
HCC1195	CCLE Cell Line Gene Expression Profiles	1.0	2.46859
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76258
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05237
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC3	CCLE Cell Line Gene CNV Profiles	1.0	1.39772
hypoalgesia	MPO Gene-Phenotype Associations	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1207-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32179
MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN009_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2839
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7631
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K56890200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7752
BCP1	CCLE Cell Line Gene CNV Profiles	1.0	1.36142
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7166
COPA	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920838
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09085
FGF23_OE_GDS3361_493_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26175
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14823
BRD-K02614439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74145
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38189
muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.345308
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.5575
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23082
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03897
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7475
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.202818
signal transduction	GO Biological Process Annotations 2015	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24255
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182153
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
A_CA_04_2009_4dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79307
CAV1_Deficiency_GDS3551_559_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Mood Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1005
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33459
TIA1_KO_GSE54418_264_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
Uterine benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34542210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18342
U1 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27245
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11399565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54422
BRD-K07820537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47408
19074878-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K26786741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01154
cysteine	Phosphosite Textmining Biological Term Annotations	1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13444
BRD-K68949590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02082
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17932
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95917
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4365
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47821
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Dehydration_Hypothalamus_GSE3110	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.61969
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863406
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11573
Muscle-fast muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44956
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19636
pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287092
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09096
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
diagonal band	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439123
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.885
CI1	CCLE Cell Line Gene Expression Profiles	1.0	1.91561
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.12758
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40119
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62054
COGN305	DepMap CRISPR Gene Dependency	1.0	8.87257
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09914
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92712
BRD-K70305913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30837
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2014	1.0	null
neuropeptide signaling pathway	GO Biological Process Annotations 2015	1.0	null
TFIP11	Hub Proteins Protein-Protein Interactions	1.0	null
G protein-coupled receptor heterodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
EMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12962
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27739
Peptide GPCRs(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91357
CES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87037
BRD-K67602895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31008
CASP2	MSigDB Cancer Gene Co-expression Modules	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
g-protein coupled neurotensin receptor activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47897
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842091
stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7146
EFO21	Achilles Cell Line Gene Essentiality Profiles	1.0	2.39883
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5244
BRD-K02535446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37211
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.967
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8059
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965044
BRD-K94506829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5658
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
DPP3_OE_GDS2653_650_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K16915521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22313
BRD-K81751970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04551
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
EPLC272H	CCLE Cell Line Gene Expression Profiles	1.0	1.96211
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.61279
BRD-K01329192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49233
BRD-K65836113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29123
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74301
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08144
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.58116
EZH2	ENCODE Transcription Factor Targets	1.0	null
trans-Golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92172
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.278654
SF268	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12339
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A05956997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31799
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-905	GDSC Cell Line Gene Expression Profiles	-1.0	-2.04177
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5434854__F2	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K60080002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0614
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cos-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4155
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
BRD-K78574327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35796
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5917
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12169
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74626943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72157
BRD-K94427708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84181
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1133
BRD-K26373865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53019
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982639
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861595
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825483
neuroactive ligand receptor interaction	KEGG Pathways	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain_CT2_Oligo 48	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76183
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14674
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06033
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.687
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
Infralimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
astroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.601283
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0594
BRD-K37213205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08872
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95434
SIN3A	ENCODE Transcription Factor Targets	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838986
BRD-K03506285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32353
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
BRD-K57228212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49806
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27923
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62603
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33491
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06242
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947208
CRCGN014_HEPG2_3H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19411
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09061
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57727
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65416
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26485
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918272
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19934
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K54143708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72304
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
U4 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.268
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047978
CSTB_KO_GDS5089_565_mouse_cerebellum and granule neurons	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JMV431	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRL_Deficiency_GDS2936_631_mouse_Retinas - 2 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K47237224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43607
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27894
PC-14	GDSC Cell Line Gene Expression Profiles	1.0	1.80031
increased prepulse inhibition	MPO Gene-Phenotype Associations	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00312
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
BRD-K42964587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04975
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86186
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
BRD-K57226763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51684
Scintillon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66439
leukemia	GeneRIF Biological Term Annotations	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19142
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8012
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K99755021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12631
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338177
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6001
ZNF672	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0802
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09857
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54572
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nephridium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
TMEM89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94709
neurotensin 69L	CTD Gene-Chemical Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.5711
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.719357
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919642
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIR34_OE_GDS2755_645_human_HCT116 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K48260102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37961
CDK19_knockdown_164_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.34091
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19729
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948168
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76133
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02032
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28542
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48983
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01784
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7059
SCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17639
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4170_KO_Atp1a2_SRP248220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.84959
BRD-K02517738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42913
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7586
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11647
abnormal startle reflex	MPO Gene-Phenotype Associations	1.0	null
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07241
skeletal muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.421016
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03355
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935207
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31223
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21345
BRD-K58757743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18848
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920603
BRD-K93875187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.068
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.113
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
BRD-K39566424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58031
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37619
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11981
ins-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270561
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06553
RCOR1	ENCODE Transcription Factor Targets	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	4.19177
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866562
BRD-K67856917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69752
NCI-H1694	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
PMC8511326__F4	PFOCR Pathway Figure Associations 2024	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937669
OCT4_KD_GDS1824_135_mouse_embryonic stem (ES)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
meclinertant	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88644
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859121
BRD-K45576113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37807
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41642
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29495
BRD-K27302831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27462
BRD-A59449038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69868
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6598
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
MTF2	ChEA Transcription Factor Targets	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873601
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00628863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08532
Neurofilament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.470375
Calcium	HMDB Metabolites of Enzymes	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56801
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Stress, Psychological	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K59970200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33044
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36826
JMV2004	DGIdb Drug Targets 2026	1.0	3.78086
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22855
JHH6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21565
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2024	1.0	null
BRD-K39489370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05438
BRD-K14116382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00487
DMD_Deficiency_GDS2996_613_mouse_Cardiac muscles from 8-week (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Alexander Disease_CNS - Brain - Olfactory Bulb (MMHCC)_GSE977	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.82912
NFIC	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21382
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26941844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27712
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1516
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68499
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23323
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16737
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46511
Lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.601
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
SUIT2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80374
BRD-K58310485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0386
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.084
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
BRD-K95963125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72842
Posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.12
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06156
BRD-K39961819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86235
BRD-K82175530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22375
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06543
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846947
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00783
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45984211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22202
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13764
BRD-K55286508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01025
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6073
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.8565
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
upregulated	GeneRIF Biological Term Annotations	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
BRD-K47309161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42347
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859121
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alveolar soft part sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08695
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17672
pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105936
BRD-K05902089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31622
detected	GeneRIF Biological Term Annotations	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4158
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88017
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
TRIM28	ChEA Transcription Factor Targets	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896274
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39917
Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15071_OE_Fezf2_SRP041818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.48321
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02572
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65596
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12437
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968676
BRD-A77292814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26272
A_CA_04_2009_4dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.14111
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868177
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A27C-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.340017
Perturb_12589_KO_Eed_SRP379883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.39276
SAMD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59913
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02319
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23536
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.32507
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35538
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59745
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37831
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23464
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05267
Neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
LN-308 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
ZR7530	Achilles Cell Line Gene Essentiality Profiles	1.0	1.80546
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01281780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81134
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06375
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02604
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62924
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49761
HDAC2	ENCODE Transcription Factor Targets	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21713
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.28553
BRD-K87418410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6354
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30721
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60619
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74464
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848613
ACCMESO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79949
CRCGN012_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49638
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37547
signal	Phosphosite Textmining Biological Term Annotations	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p22 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17079
CTNNB1_Inactivation_GDS2984_628_mouse_Intestinal crypts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42269
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06213
r2 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18032
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	2.15919
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994576
wi26va4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49393
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850326
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14617
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53993775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62661
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBB_KO_GDS3906_492_mouse_Testis -  14 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2886
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934593
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42960858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16992
mantle zone of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17943
NTS	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096176
BRD-K11008696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99366
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894541
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4257
CHD1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81144230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84457
VCAP	DepMap CRISPR Gene Dependency	1.0	6.14258
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MDCK-MDR1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22052
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45995
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neurotransmitter receptor activity	GO Molecular Function Annotations 2015	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09843
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05322
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46149271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58194
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37331547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07688
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K72278003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28855
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.79275
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23699
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96735
A2058	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.73126
BRD-K41809155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.508
H-1299	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29149
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.58349
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05131
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.71787
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K59046641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20793
extracellular	Phosphosite Textmining Biological Term Annotations	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Mouse - Motor Cortex - Cross-Species Cluster - Astrocyte_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
estradiol_rattus norvegicus_gpl85_gds2311	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ncih727	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14073
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49978
inner CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961047
[D-Trp<sup>11</sup>]neurotensin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BRD-K96377358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6933
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18282
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2138
Disease	Reactome Pathways 2014	1.0	null
BRD-K89532826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01475
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063076
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A817-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RS11846	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.987627
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79965790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05965
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.608643
BRD-K48188521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17748
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.32868
increased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12308
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51672
Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49064
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
BXPC3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27539
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05406
BRD-K72183943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61145
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00118
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851707
BRD-K09328667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77065
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	2.03789
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32201
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848118
BRD-K22474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74517
BRD-K03697080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09168
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39087168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48985
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07241
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K63188051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72004
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.71231
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00666
Dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24933
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95034
BRD-K26472648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01701
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33531
BRD-K25056189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29415
BRD-K67406305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41184
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39906
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13492
medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402901
BRD-K67126097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16981
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857976
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.9224
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830035
SKUT1	DepMap CRISPR Gene Dependency	1.0	2.88502
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97153
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0YX-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87154
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769855
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
BRD-K69826976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02981
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IT-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2240_KO_L2hgdh_SRP093280	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.56332
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15443
BRD-K23292451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12691
BRD-K15523383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46977
JMV458	DGIdb Drug Targets 2026	1.0	3.78086
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE103297_1_v_0_glis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37619154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46697
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01498
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7458
YAMATO	DepMap CRISPR Gene Dependency	1.0	6.26788
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30196
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18325
G protein-coupled neurotensin receptor activity	GO Molecular Function Annotations 2025	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.11119
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19443
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40236
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0044
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.091
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72961
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GPCR ligand binding	Reactome Pathways 2024	1.0	null
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91172
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19341
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K05090634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.04491
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7851
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19298
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_3_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03176
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01333
BRD-K21196859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06541
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.88194
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Conduct Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A95683194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02603
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22519
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4116
BRD-K02882086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01665
Endometriosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.985
BRD-K87209752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06768
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37902
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47318
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10575
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5801
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17609
Trypanosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
YY1	ENCODE Transcription Factor Targets	1.0	null
BRD-K16935435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51564
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24491
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05487
Alzheimer's disease 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TMEM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77881
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18648
MUTZ8	DepMap CRISPR Gene Dependency	1.0	2.30888
REST_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.805213
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08727
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30739
BRD-K28926538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13013
BRD-K30269093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14576
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31413
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844844
BRD-K30563122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11379
depends	GeneRIF Biological Term Annotations	1.0	null
cluster	GeneRIF Biological Term Annotations	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31219
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.337751
MG-63	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14639
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89123
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02471501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4659
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968096
BRD-K65705295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26878
BRD-K91738126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39745
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.38295
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33915
HT-29 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92297
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948168
BRD-K61742182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02133
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63645840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.81796
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12919
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222224
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38324
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03257
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48612
pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224398
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
ACSS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2007
SREBF1	ChEA Transcription Factor Targets	1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.568025
Astrocyte_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-44-MYT1L_MYT1L	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89135
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.578416
CDK9_druginhibition_183_GSE48258	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.215984
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.14781
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17304
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8737
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25079
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08213
BRD-K09258973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43867
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47849061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25198
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.82637
BPGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62144
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63505
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21023
BRD-K43468685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13477
STAT1	ChEA Transcription Factor Targets	1.0	null
REST_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47028303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24982
neuropeptide signaling pathway	GO Biological Process Annotations 2025	1.0	null
BRD-K87951090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68031
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14923
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.985
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25598
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72626
BRD-K31222955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92818
SKNBE2	DepMap CRISPR Gene Dependency	1.0	5.05905
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01747
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.559652
BRD-K23857235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19501
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24128
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
brain	GTEx Tissue Gene Expression Profiles	1.0	2.18987
OC-314	GDSC Cell Line Gene Expression Profiles	-1.0	-2.37697
YY1	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
rhombomere 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58521
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26375
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08812
Substance-Related Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47649
BRD-K94697940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37285
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
SEPTIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90206
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0294
Perturb_15775_OE_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.37832
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01532
BRD-K62541003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7163
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.827
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105936
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842863
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21786
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100288_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10584
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01045
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66389
BRD-K72439355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32603
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.940451
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866176
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454512
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2991
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71279
Anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
layer 4 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19643
BRD-K85821758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27548
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075789
pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692493
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856106
pontomedullary hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35477
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
hsa-miR-4742-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49745
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98889
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35745
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01518
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70519
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A06840811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36462
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01722
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44169
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257572
IGROV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.89054
neuropeptide receptor activity	GO Molecular Function Annotations 2023	1.0	null
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PCGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90308
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53731
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05101
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11373
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41972460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53626
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75073
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057844
BRD-K69528787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2954
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17536
plasma	Phosphosite Textmining Biological Term Annotations	1.0	null
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08427
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
ATOH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56848
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7474
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77038
REST_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02315
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16193
BRD-K06489778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43528
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34762
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89614
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10494
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35535
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-604	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
phenotype	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1953
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31665
BRD-K00877314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70855
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83436
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Neurotensin receptor	InterPro Predicted Protein Domain Annotations	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66456
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574017
BRD-K37830990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41021
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31332
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74621
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH526	DepMap CRISPR Gene Dependency	1.0	4.07963
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	3.62434
SKNBE2	CCLE Cell Line Gene Expression Profiles	1.0	1.70236
Alcoholism	HuGE Navigator Gene-Phenotype Associations	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10805
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82688
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.973766
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13704
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79293
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10455
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052137
HS746T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48719
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92139
olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.582019
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887031
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875972
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71722
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39016
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07409
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32482
BRD-K48276655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4065
Prp19 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.03
Trp<sup>11</sup>-neurotensin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.576
increased thermal nociceptive threshold	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89243
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01364
496100450_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01184
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36236
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23252
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24255
BRD-K52473839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33145
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17881
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
DNAJC2	Hub Proteins Protein-Protein Interactions	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902151
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.5576
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.76517
BRD-K44509164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37053
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057583
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49659
BICR22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7461
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4097
alveolar soft part sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00035
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36267
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
CAV1_KO_GDS3551_366_mouse_mouse heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26078
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.379
BRD-K44260904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33671
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
post-traumatic stress disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
Commitment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.559254
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.655024
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28278
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71748
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55453160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06039
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02668
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1202
JMV431	DGIdb Drug Targets 2026	1.0	3.78086
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98484
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89491
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08556
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58685
PECAPJ49	CCLE Cell Line Gene Expression Profiles	1.0	1.60559
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49561
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04344
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1196
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958237
abnormal thermal nociception	MPO Gene-Phenotype Associations	1.0	null
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94929
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22273
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934593
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881394
neurotensin	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08142
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.48254
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
DB	DepMap CRISPR Gene Dependency	1.0	5.89663
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5736
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74728
BRD-K74285424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68442
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
BRD-K92239253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22049
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
CRCGN012_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28305
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70099
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70566
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83141
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
BRD-K05417183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59245
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21524
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00793
BRD-K45378289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38561
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4494
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72334
N1E-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
Brain Lower Grade Glioma_LGG_TCGA-QH-A6XA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_1_vs_3_NOT_Group_2_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal cns synaptic transmission	MPO Gene-Phenotype Associations	1.0	null
BRD-K66526269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22767
SNU1196	CCLE Cell Line Gene Expression Profiles	1.0	1.44136
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81614
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68777
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12227
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057118
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K77797589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18808
BICR16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56992
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85965830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25745
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63791
Leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
GPCRs, Class A Rhodopsin-like(Mus musculus)	WikiPathways Pathways 2014	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950383
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66951
HCC2429	DepMap CRISPR Gene Dependency	1.0	2.58283
BDP1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055013
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173836
Anterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
ntr1	GeneRIF Biological Term Annotations	1.0	null
BRD-K60662039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11255
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85074
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10909
EW-22	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43819
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062832
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1432
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08915
BRD-K58300049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08876
BRD-K45516283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32258
BRD-K15378071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39673
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
LPS510	DepMap CRISPR Gene Dependency	1.0	2.33359
hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18561
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80887
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00994
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.860126
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986636
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14264
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.865
BRD-K06718330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08155
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC27A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964138
BRD-K54751614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91392
embryonic neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252261
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16767
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40124
CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55231
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Multiple benign melanocytic nevi_Epidermis_GSE3189	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.96373
BRD-K82477786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66646
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
496100331_TCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54653
pituitary	GeneRIF Biological Term Annotations	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	2.36415
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48187
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27827
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JMV2004	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
VARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70785
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25883
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38131
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BL1475 (PNKP)	NURSA Protein Complexes	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.7642
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6134
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
g-protein coupled peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
TC205	DepMap CRISPR Gene Dependency	1.0	2.66435
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45142
SUZ12	ENCODE Transcription Factor Targets	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51468
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04843
Diisocyanate-induced asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.635
Perichromatin fibrils	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76655
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08342
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mental Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
CHP-212	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.558
MAZ	ENCODE Transcription Factor Targets	1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K34489843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17764
RBM8A	MSigDB Cancer Gene Co-expression Modules	1.0	null
CENPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05935
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.25
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
19061838-TableS14	GeneSigDB Published Gene Signatures	1.0	null
agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.919261
BRD-K48861177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53058
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26636241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24687
Carcinoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.64793
BRD-K62650632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28133
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33142
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28276
BRD-K76336129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96613
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.86181
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.764
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04925
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82433
BRD-K97487406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26557
Pedal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02616
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.84803
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39906
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69742
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	2.7444
BRD-K69132276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0366
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of membrane potential	GO Biological Process Annotations 2015	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.340017
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HS-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6384
ONECUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76787
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88209
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.987415
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44665
BRD-K09304381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51909
BRD-K13087600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.221
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45869
BRD-K59232896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19367
JMV457	DGIdb Drug Targets 2026	1.0	3.78086
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49408
BRD-K06251362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17329
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
compared	GeneRIF Biological Term Annotations	1.0	null
BRD-K71737889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55354
BRD-K06816455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47373
Type 2 diabetes mellitus_Hepatic Tissue_GSE2899	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.41194
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ability	GeneRIF Biological Term Annotations	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48487
BRD-K78965436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92103
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02214
Quiescent neural stem cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63105
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96176
ins-1e cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26039
SREBP1-19666523-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Chagas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EN	CCLE Cell Line Gene Expression Profiles	1.0	2.47906
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68588
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37355
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888359
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923688
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06675
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62055
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68501
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74162
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40367360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68415
NB1	DepMap CRISPR Gene Dependency	1.0	2.09573
TKKK	DepMap CRISPR Gene Dependency	1.0	2.32048
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.594
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-506-MAFA_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23220745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40826
PFSK1	DepMap CRISPR Gene Dependency	1.0	5.32934
vii	GeneRIF Biological Term Annotations	1.0	null
Organ system benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02025
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102078
TBP	ENCODE Transcription Factor Targets	1.0	null
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3987
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.24138
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46423
hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187856
BRD-K29028138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80256
T3M4	CCLE Cell Line Gene Expression Profiles	1.0	1.62947
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.06576
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
BRD-K88351048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14743
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07365
BRD-K71644199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2998
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904713
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29596
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
BRD-K01371603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23783
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
MECLINERTANT	DGIdb Drug Targets 2026	1.0	3.78086
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2627
FAM234A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8363
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2226
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59268
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44267
pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.536229
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48006
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37782
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32598
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_Panc1_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00856
BRD-K69744558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0441
biological_process	GO Biological Process Annotations 2015	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K62803063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13279
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K18768055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18493
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65239
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Peptide ligand-binding receptors	Reactome Pathways 2014	1.0	null
genistein	Phosphosite Textmining Biological Term Annotations	1.0	null
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15565
Uterine fibroid	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31503053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09717
Adhesive extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.273
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12959
MZT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTB_KO_GDS5090_198_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K43418395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05486
BRD-K37527826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43319
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain_CT2_COP 41	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ntr3	GeneRIF Biological Term Annotations	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98441254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90424
[<sup>125</sup>I]neurotensin (human  mouse  rat)	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.08699
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37619
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
recycling	GeneRIF Biological Term Annotations	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
CRCGN013_HEPG2_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0023
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08307
tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.62991
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22526
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25672
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61864
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19229
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.46482
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48736
MYBL2	ENCODE Transcription Factor Targets	1.0	null
B-Cell Malignancy, Low-Grade	DisGeNET Gene-Disease Associations	1.0	null
abnormal gait	MPO Gene-Phenotype Associations	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71094
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13369
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978988
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K80535598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.048
Proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925497
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10596
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36575696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33695
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15431
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
BRD-K73182084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7045
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3953
B3GNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00777
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900765
BRD-K96249452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.041
BRD-K80210288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27297
BRD-K25931705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13569
PMC3930188-813067.f1.pdf-97-NR0B1_NR0B1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71496240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97803
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30585
ZNF500	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88737
Cues	HuGE Navigator Gene-Phenotype Associations	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34696
BRD-K29420358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57687
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09368
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
BRD-K02159857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31803
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06113
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80983
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9047
CREB1	ENCODE Transcription Factor Targets	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57184137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66563
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86979
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75062
CHD7	ENCODE Transcription Factor Targets	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
BRD-K08259535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02561
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57821544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44625
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8291
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92257
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06562
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00372
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.60406
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847461
SKMEL24	DepMap CRISPR Gene Dependency	1.0	2.00545
BRD-K90230495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14149
CAL-85-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.09115
BRD-K73582217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35965
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5236
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.625924
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14157
icSARS CoV_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.12192
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10877
Perturb_3482_KO_Mcph1_SRP401970	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.65229
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18045
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6886
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910784
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.276158
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44056
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05884
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18501
astroglial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.613764
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02568
BRD-K28640166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06334
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5783
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R5-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828479
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43541
BRD-K25312635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30997
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244199,GSE244200_0_v_1_chmp5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate gland smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33294
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23792
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Female reproductive organ benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.69879
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7951
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.48013
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9186
BRD-K32856496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15931
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46185
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921663
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.6125
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05301
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ISCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36115
proposes	GeneRIF Biological Term Annotations	1.0	null
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33925
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452584
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29347
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45959
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05572
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.77123
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50921
BRD-K04358482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25395
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.625
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11839
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966115
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
BRD-K39046749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1958
TCF3	ChEA Transcription Factor Targets	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01943
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03365
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29391
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03403
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45924
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46451
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04733
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41081
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-493-ENSG00000186487_MYT1L	Rummagene Transcription Factor Associations 2026	1.0	null
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1105
c83	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18292
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719524
rhombomere 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2054
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98431828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26173
Chronic lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78469924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19219
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85888
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U4/U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39029546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67557
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ELF1	ChEA Transcription Factor Targets	1.0	null
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39338
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26599
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937666
BRD-K11423211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01228
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.550106
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
SREK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.52506
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12622
STK31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2712
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75073
SCLY	ChEA Transcription Factor Targets	1.0	null
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3422
BRD-K69229416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37073
BRD-K86750448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11602
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30857
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8264
BRD-K26214026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03942
BRD-K86158100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43417
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43879
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09679
697	CCLE Cell Line Gene Expression Profiles	1.0	1.55205
Bloodstream form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
abnormal locomotor coordination	MPO Gene-Phenotype Associations	1.0	null
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38068
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430695
SIRT3_KO_GDS4817_416_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	2.11011
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180518
BRD-K43192646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03784
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94119
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26915
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8674
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7824
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55484
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
BRD-K19103068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30322
MYC	ENCODE Transcription Factor Targets	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881593
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86482
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03641
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
BRD-K83586473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14064
Eye_CT1_glial cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
r5 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26784
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08616
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53337
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26682
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40119
BRD-K83229680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07988
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888696
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01108
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16509
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04635
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03756
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Brain Lower Grade Glioma_LGG_TCGA-TM-A84S-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
Recognition 	HuGE Navigator Gene-Phenotype Associations	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5324
TCF12	ENCODE Transcription Factor Targets	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966115
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02049
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atherosclerosis_Aorta Smooth Muscle Tissue_GSE420	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53123
BRD-K78983822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30807
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479312
Senescence_CNS - Brain - Hippocampus (MMHCC)_GSE5078	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.54993
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14338
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96527
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX11	ChEA Transcription Factor Targets	1.0	null
BJ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K46311453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77682
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36493118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19508
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.171149
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05976
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12029
POLR3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15341
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59028365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55114
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.04978
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07409
BRD-K91511557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22334
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01662
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65653
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78441
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.736
Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.75617
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054103
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45667
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49969
BRD-K23197669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28023
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60249
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00057
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
either	GeneRIF Biological Term Annotations	1.0	null
BRD-K40145790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87504
ATM_knockout_16_GDS1544	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.4752
BRD-K81206010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09889
BRD-K25269762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27654
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.35771
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584022
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14909
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40335
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-373MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04243
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	2.19113
Central amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
KDM5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29246
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89181
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.104
BRD-K13301506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33923
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6012
BRD-K86805916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51881
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04832
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828545
BRD-K92632379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07433
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H630	GDSC Cell Line Gene Expression Profiles	1.0	1.82343
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Venom duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52816
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31332
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.422
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07627
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64553072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54876
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95479
NB(TU)1-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58118393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21327
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.315586
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11073
BRD-K67859584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2647
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33337
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861531
BRD-K12399715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10781
BRD-K84143716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57453
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
BRD-K50004365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44782
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30492
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01836
Inflammation	CTD Gene-Disease Associations	1.0	1.05648
mouse	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K73637411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1054
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.257
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9112
BRD-K28357534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13776
BIN67	DepMap CRISPR Gene Dependency	1.0	4.29535
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44281
BRD-K52423731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53808
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20989
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.179752
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36619
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943057
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12932
abnormal touch/ nociception	MPO Gene-Phenotype Associations	1.0	null
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08513
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33538
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0372
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29934
Signal Transduction	Reactome Pathways 2024	1.0	null
Splenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44955
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ghrelin	GeneRIF Biological Term Annotations	1.0	null
Cerebral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25995
BRD-K75429775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53682
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94638
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-2.1002
hsa-miR-3975	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08897
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28483134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4692
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06223
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55408
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.868658
TAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21137
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849946
BRD-K42296822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01323
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.379
BRD-K46951445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57012
Perturb_12084_KO_Brca1_SRP050547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12506
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959206
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412391
MCAD_KO_GDS4546_423_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
BRD-K30973947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36482
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77661
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15425
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6458
BRD-K53354260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29582
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K37906141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09146
ZNF124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75582
BRD-K51577639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30579
BRD-K87383650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11351
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04283
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12227
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37148
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17343
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841662
BRD-K81471597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10243
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21142
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16637_KO_Drd2m_SRP377988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6436
BRD-K77814566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23485
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.73463
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive organ benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933768
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
healthy	GeneRIF Biological Term Annotations	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2357
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
KM-12C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45392
PML	MSigDB Cancer Gene Co-expression Modules	1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32322
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42165
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02403
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37313
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4175
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	2.01119
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01877
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05912
isoflurane_rattus norvegicus_gpl341_fear_gds2037	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
levetiracetam_rattus norvegicus_gpl1355_brainstem_gds1864	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60056
BRD-K98529522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44204
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
BRD-K44722328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3065
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38043
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
95C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8088
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00097
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08092
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
intermediate stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18297
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40236
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07545
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22123
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880278
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AAR2	Hub Proteins Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.66071
GMCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81351
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13174
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26186
BRD-K50045741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45662
Rhomboid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.94877
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Radula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02293
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16733
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3024
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96965
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.295739
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.67253
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.49124
LMSU	CCLE Cell Line Gene Expression Profiles	-1.0	-2.67045
meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092231
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91202
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98139
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03913
residue	GeneRIF Biological Term Annotations	1.0	null
BRD-K71544970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13139
BRD-A20208638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49401
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25376
Visceral leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74971
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.2776
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5992
BRD-K00950228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33498
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29051
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58584
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934593
BRD-K90562751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04945
BRD-K33897007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19665
Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1712
BRD-K95863777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39629
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8125
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01618
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08384
Rett Syndrome_frontal cortex_GSE6955	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.65812
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
HS729	CCLE Cell Line Gene CNV Profiles	-1.0	-1.448
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33593
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930738
BRD-K86086888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5226
BRD-K58680513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14011
g-protein-coupled	Phosphosite Textmining Biological Term Annotations	1.0	null
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18913
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	2.12422
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888623
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07534
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77889
BRD-K28522188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25401
sensory perception	GO Biological Process Annotations 2023	1.0	null
BRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79091
BRD-K30628727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01844
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68004
dbr95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.91
adenomas	GeneRIF Biological Term Annotations	1.0	null
BRD-K54364215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02188
MUTZ5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62283
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38969
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10013
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neural stem cell_Hypothalamus_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17743
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
BRD-K86978618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36414
BRD-K80622681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22208
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2307
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LTK	MSigDB Cancer Gene Co-expression Modules	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.252
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
BRD-K44743425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36587
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047802
decreased startle reflex	MPO Gene-Phenotype Associations	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.741
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03223
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23461
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.70471
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3684
BRD-K23243038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48393
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81719
T3M4	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20471
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39161
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83302
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49815
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56251
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4474-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8737
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44249
Perturb_13979_KO_Dnmt3a_SRP168393	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.3897
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-2.74179
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16437
TC32	DepMap CRISPR Gene Dependency	1.0	3.10762
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77621
BRD-K96510191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97734
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14434
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11187
abnormal synaptic transmission	MPO Gene-Phenotype Associations	1.0	null
Perturb_14004_OE_Kcnj2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K48325920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42661
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05972
substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.406051
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.81392
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00749
r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37046
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Checkpoint clamp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21878
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845127
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06859
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00748
ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58322
amino-acid-substitution	Phosphosite Textmining Biological Term Annotations	1.0	null
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.838252
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ntsr1	GeneRIF Biological Term Annotations	1.0	null
BRD-K19264579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1643
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	172.991
BRD-K27680690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32235
Lymphatic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
HS343T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99319
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03101
PANC0813	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13353
BRD-K63730594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09467
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962559
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.781
MEL270	DepMap CRISPR Gene Dependency	1.0	3.13172
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
contulakin-G	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824496
UBE2L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68787
IGROV1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00249
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041086
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11112
BRD-K40964045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03387
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38189
BRD-K80483148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.268
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05919
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03233
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06435
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
BRD-K02675272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.015
P4HB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09887
MAN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89868
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4186
enzyme-inhibitors	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K12099407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23271
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842514
RBPJ	ChEA Transcription Factor Targets	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIMA	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17194
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956253
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
sensory perception	GO Biological Process Annotations 2025	1.0	null
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8479
BRD-K33863933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0152
USF2	ENCODE Transcription Factor Targets	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small nuclear ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07197
phospholipase c-activating g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33326
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	0.862935
Precatalytic spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.728
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07753
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE216538_5_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42966
GSE93309_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
Basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961959
Hip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067822
CRCGN008_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0625
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54259
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1926
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Levocabastine	HMDB Metabolites of Enzymes	1.0	null
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53594
BRD-K94442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20403
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0498
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39208
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08078
RRM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8246
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17887
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977369
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13058
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Get-1_Deficiency_GDS2629_161_mouse_embryonic skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97589
Isolated growth hormone deficiency type IB	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
Midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.724
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44223
BRD-K01358985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04774
neuropeptide signaling pathway	GO Biological Process Annotations 2023	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23023
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36274
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.65056
anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.697808
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915139
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35827
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38137
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05483
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
constitutive	GeneRIF Biological Term Annotations	1.0	null
BRD-K99944747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07632
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10475
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03855
hsa-miR-1202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K51858914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12935
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8409
BRD-K94728263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01322
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03078
BRD-K45361857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12819
NDUFB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47722
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74532
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20407
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89491
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82544
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98879
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 2 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1481
BRD-K34851865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31227
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
rat	Phosphosite Textmining Biological Term Annotations	1.0	null
496100287_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.62785
TTC642	DepMap CRISPR Gene Dependency	1.0	4.71338
BRD-K64904523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19242
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
BRD-K92018859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56022
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
Perturb_15083_KD_Nsd1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.2412
PCM6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60948
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G protein-coupled receptor activity	GO Molecular Function Annotations 2023	1.0	null
communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.890488
neurological system process	GO Biological Process Annotations 2015	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12622
BRD-K26844643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42613
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51092
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915428
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
hsa-miR-3972	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.694979
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041619
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94333
Non-odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47065
NCIH660	Achilles Cell Line Gene Essentiality Profiles	1.0	1.18903
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34984
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.59951
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85231
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23854
BRD-K69471644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6565
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855872
BRD-K92884779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10772
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
BRD-K48059443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13431
pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.924626
K562	CCLE Cell Line Gene Expression Profiles	1.0	2.26005
BRD-K44521151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1163
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0647
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0444
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839423
BRD-K23905877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11471
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21284
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
penta-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70784
BRD-A63590986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12417
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70707
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	1.51941
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3488
luminal	GeneRIF Biological Term Annotations	1.0	null
JMV458	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
CAKI2	DepMap CRISPR Gene Dependency	1.0	3.99093
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06619
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510992
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13202
Rectum adenocarcinoma_READ_TCGA-F5-6864-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07393
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22437
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67881
corpus callosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428783
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867013
Pauciarticular juvenile arthritis_Peripheral blood mononuclear cell_GSE1402	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.88587
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0028
BRD-K93590856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20267
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU840	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33618
BRD-K33573676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32823
MEC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12294
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32863
Peptide ligand-binding receptors	Reactome Pathways 2024	1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34703146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59086
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827104
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966848
r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2438
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14395
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2702
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.688
Perturb_5526_KO_Crtc1_SRP279598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32849
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959583
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.2347
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40119
NFIA_Deficiency_GDS2775_640_mouse_Postnatal brains (at P16)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K47998973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09269
bcells	GeneRIF Biological Term Annotations	1.0	null
rhombomere 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02902
BRD-K00537235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53125
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45784
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03835
SJSA1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.355
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72053
BRD-K14907323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10373
NMB	DepMap CRISPR Gene Dependency	1.0	2.75878
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965675
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89105
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.39585
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45215
system process	GO Biological Process Annotations 2015	1.0	null
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47007
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868177
neuropeptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50396
BRD-K42435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70846
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
BRD-K10784927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53961
CRCGN017_MCF10A.WT.HP_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0758
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41459
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7888-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.58
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055635
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20781
GSE101239_3_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826623
BRD-K18307373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30375
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
BRD-K38571893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14201
BRD-K07576726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6671
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.44322
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22052
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49003
degree	GeneRIF Biological Term Annotations	1.0	null
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922378
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06249
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48708
REST_Panc1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
BRD-K54100199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28626
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00833
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12889
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08202
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36978
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34577
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46714
Anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
SARS-BatSRBD_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43906
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05607
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43586
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23899
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.58987
BRD-K03461876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1733
BRD-K50291875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41127
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042244
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.69259
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXO1	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.840518
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Obesity_Adipose tissue_GSE4692	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.64504
Plant scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-545	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43605
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05543852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32705
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32812
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06362
FOXP1	ChEA Transcription Factor Targets	1.0	null
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80071
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86269
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0926
NCI-H720	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65833
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.76573
Signaling by GPCR	Reactome Pathways 2024	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879981
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5396
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35661
levocabastine	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411251
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384013
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14392329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08276
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GPCR ligand binding	Reactome Pathways 2014	1.0	null
CLPB	Hub Proteins Protein-Protein Interactions	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79347939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01016
BRD-K90052868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19556
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12235
Cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.518
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61536
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41557
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24383
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.2886
NB7	GDSC Cell Line Gene Expression Profiles	1.0	1.6174
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24707
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21356
697 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37343
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
increased thermal nociceptive threshold	MPO Gene-Phenotype Associations	1.0	null
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ntr2	GeneRIF Biological Term Annotations	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67553
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948168
Trypomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
BRD-A43164341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13441
PABPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91396
CRCGN011_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0038
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0227
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08843
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852671
astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.620621
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834253
BRD-K26217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29173
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82598
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63133
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13424
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.43255
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09875
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59196
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80443
BRD-K57786028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18961
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05036
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25322420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25171
ZFP36L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28271
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
BRD-K66619295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.25705
UMUC7	DepMap CRISPR Gene Dependency	1.0	3.27075
BRD-K06166879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71847
KDM4A	ENCODE Transcription Factor Targets	1.0	null
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24836
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15303
Alcohol use disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.651777
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082417
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11922
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ebolavirus(ZEBOV)_6hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.04277
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K67337799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28653
BRD-K81544427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15577
BRD-K84663394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92692
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951597
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
left colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329727
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5716
BRD-K65005311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30393
substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452584
BRD-K34798837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50875
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tyrosine	GeneRIF Biological Term Annotations	1.0	null
BRD-K76353834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01662
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NTS	Pathway Commons Protein-Protein Interactions	1.0	null
EB1	CCLE Cell Line Gene Expression Profiles	1.0	2.15856
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81716
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18205
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.95014
BRD-K48195722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35922
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23126
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G alpha (q) signalling events	Reactome Pathways 2024	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29891
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72507
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37816
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3587
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
17533364-Table2	GeneSigDB Published Gene Signatures	1.0	null
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24709
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Peptide GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41678
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55784
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
BRD-K07420629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54024
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980219
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
display	GeneRIF Biological Term Annotations	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07688551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28076
SARS-CoV MA15_Day4-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.784243
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00486
single	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09362
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362646
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
ntsr2	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87896
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72494
BRD-K56120807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04137
BRD-K94777797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86971
FAHD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.029
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40647
BCP1	CCLE Cell Line Gene Expression Profiles	1.0	3.40797
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.0812
face	GeneRIF Biological Term Annotations	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97133
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.5301
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42513
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5476
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01662
BRD-K41620124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46747
tcf3_20154672_cd4pos_cd8pos_thymocytes_thymus_lof_mouse_gpl6246_gse19923	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.24799
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962697
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867968
BRD-K04092807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77317
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
several psychiatric disorders	GAD Gene-Disease Associations	1.0	null
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04517
BRD-K27653895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07974
KNS42	CCLE Cell Line Gene CNV Profiles	1.0	1.62946
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063118
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
JURKAT	DepMap CRISPR Gene Dependency	1.0	5.2574
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85984
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16424
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832623
BRD-K39074860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50719
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16118
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052235
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.288
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920603
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56366
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10801
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13429
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23932
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45317
BRD-K71755056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36545
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35727
BRD-K09378334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17551
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62963
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42859
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61516
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.44139
receptors	Phosphosite Textmining Biological Term Annotations	1.0	null
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
Neuroendocrine tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907281
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27055
BACH1	ENCODE Transcription Factor Targets	1.0	null
BRD-K87712055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68957
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.757432
Benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.203
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46399
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05031
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03491
Diagonal band	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
Cardiac stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5888
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03365
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29376
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957149
BRD-K31408750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34994
BRD-K42253676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86558
BRD-A20477000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40944
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63892
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828852
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
MRK-nu-1	GDSC Cell Line Gene Expression Profiles	1.0	1.84624
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47798
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0356
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81994
ADSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29625
RABGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66804
SW156	DepMap CRISPR Gene Dependency	1.0	7.37272
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.6618
BRD-K54549319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41403
ORMDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43218
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02747732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16993
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38668
BRD-K63030320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06578
PAXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18825
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01831
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_CT2_Oligo L5-6 OPALIN LDLRAP1	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42198
abnormal gait	MGI Mouse Phenotype Associations 2023	1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17895004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10666
Exocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871554
BRD-K50201262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17839
GSE223008_7_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE138228,GSE138230_2_v_1_cdkn1c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33940145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38999
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1726
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896607
S117	DepMap CRISPR Gene Dependency	1.0	7.71798
BRD-K03254663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18836
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0519
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22983
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
BRD-K49467822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.754
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
BRD-K29200961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10202
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17359
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84732
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895343
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29320859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69097
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87515
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B6-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56488838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08707
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
BRD-K38574421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00754
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
A7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
BRD-K49345010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83779
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58907
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.382884
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13901
BRD-K58863944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04625
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
SIMA	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85458
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.87691
BRD-K41355409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72977
abnormal pain threshold	MPO Gene-Phenotype Associations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57425
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12443
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09551
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19932
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28963
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80478
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54151
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33103
MDAMB415	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38298
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.772
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72681425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93113
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61407677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76128
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5051
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE230263,GSE230265_6_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Reservosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
Perturb_5524_KO_Trpm7_SRP409200	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17141
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A80010944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19553
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33678
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
EOL-1-CELL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K46607226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41846
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU-4475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
CSTB_KO_GDS5089_169_mouse_Cerebrellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HIV - Human immunodeficiency virus infection_T lymphocyte_GSE2504	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.796971
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.025
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	3.50928
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61199074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00061
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
HCC1419	GDSC Cell Line Gene Expression Profiles	1.0	1.86144
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38543
Neurotensin	CTD Gene-Chemical Interactions	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66441
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.784997
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900765
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09467
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20535
MOB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89679
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23583
NALM16	DepMap CRISPR Gene Dependency	1.0	3.08715
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059685
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51927648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14068
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTB_KO_GSE47516_677_mouse_mouse cerebellum P7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Conduct disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Schizophrenia 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
BRD-K15708264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63399
Venom apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848945
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72328
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17136
INS-1E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057647
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851233
cercopithecus-aethiops	Phosphosite Textmining Biological Term Annotations	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31549
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9226
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71187
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ends	GeneRIF Biological Term Annotations	1.0	null
BRD-K93755725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90048
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053167
MRPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44433
BRD-K53191200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30825
tms	GeneRIF Biological Term Annotations	1.0	null
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.319
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28101
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29263
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85158
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22518
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50147
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60958
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00912
Globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89866
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079193
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.562441
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.167
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43904
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05603
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.388
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40126
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913261
ZNF277	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983561
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.59913
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88927
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26386
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01416
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46639
SKNO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05851
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05393
LU-134-A	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
Ventral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
cytokeratin	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12648
BRD-K64183190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00938
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57846
NCIH1734	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86703
496100429_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05771
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.37691
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74262
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6179
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61228
PHGDH_KO_GDS2874_125_mouse_embryonic head tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A50913845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27743
BRD-K64730761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16236
BRD-K56801250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1805
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86828
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate	GeneRIF Biological Term Annotations	1.0	null
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00463
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30067
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50973
Becker	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46518
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K76251351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16057
NRF1	ENCODE Transcription Factor Targets	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	3.09782
BRD-K30727702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01071
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07478
neuropeptide receptor activity	GO Molecular Function Annotations 2025	1.0	null
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K85649685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24871
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827434
H4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48127
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
BRD-K30221348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96409
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.73364
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56533
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33717
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	1.34591
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32497
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03995
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00259
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38123
HMGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80898
BRD-K38538662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51736
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14123
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052059
U2 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56419
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449886
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissue	GeneRIF Biological Term Annotations	1.0	null
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.WT.HP_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15431
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921663
testosterone_rattus norvegicus_gpl1355_gse15243	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.638809
BRD-K82667180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00711
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86163
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K07486034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32967
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
BRD-K60509482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0353
RCOR3	ChEA Transcription Factor Targets	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
NCI-H1581	COSMIC Cell Line Gene Mutation Profiles	1.0	null
alcoholism	GAD Gene-Disease Associations	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10245
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.825053
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	3.25793
Chronic lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51735
BRD-K54839019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40179
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47304
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33622
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08307
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932962
BRD-K68968009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78573
IRX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09264
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.383
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969585
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_4473_KO_Prdm12_SRP304476	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.4203
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36141
Perturb_16629_KO_Kir4.1_SRP133512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.00805
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9058
sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180652
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08859
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77791
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26224
EFE184	DepMap CRISPR Gene Dependency	1.0	2.20739
BRD-K08659289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55734
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5524
BRD-K97086564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21124
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981428
unusually	GeneRIF Biological Term Annotations	1.0	null
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22304
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38949
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49602
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.968
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09818
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04237
NQO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29608
BRD-K32380923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0881
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43921
BRD-K79204912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22685
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31735
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77733
BRD-K21420222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72531
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22871
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30875
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
B-cell chronic lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90574
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898284
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27311
Arcuate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6159
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11003
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48167
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24679
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947296
Brain Lower Grade Glioma_LGG_TCGA-HT-7474-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858083
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
gpr39	GeneRIF Biological Term Annotations	1.0	null
BRD-K91467861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59876
membrane part	GO Cellular Component Annotations 2015	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921088
496100629_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30911
BRD-K33702515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35792
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888063
SCS214	DepMap CRISPR Gene Dependency	1.0	4.15419
BRD-K61139423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19711
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47173
r2 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18385
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546136
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04567
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2695
GSE138024_2_v_3_rgs4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	1.62737
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.704
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
Mesenteric adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4909
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4243
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14411
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12091
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.5083
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86586
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857869
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4462
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
CORL47	DepMap CRISPR Gene Dependency	1.0	2.01692
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-33	GDSC Cell Line Gene Expression Profiles	1.0	1.85533
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13964
BL4485 (KDM5C)	NURSA Protein Complexes	1.0	null
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
dihydroergotamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43904
BRD-K31992830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52558
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98061543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90333
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09019
GSE224877_3_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34452
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75997
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57832
ST486	CCLE Cell Line Gene Expression Profiles	1.0	1.36239
el2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01913
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus preopticus medianus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.176
Perturb_8513_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06316
BRD-K01296372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28258
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
BRD-K20271744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0403