association dataset threshold value standardized value primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.54347 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.69818 ETS2_KD_GDS5040_9_human_H441 lung cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Idiopathic generalized epilepsy 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.01 GSE102467_1_v_0_pazopanib_human RummaGEO Drug Perturbation Signatures -1.0 null SKRC20 CCLE Cell Line Gene Expression Profiles -1.0 -1.62841 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21542 GSE128054_1_v_0_myt1_human RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.982727 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07797 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06683 Anterior cingulate area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01313 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF217-24962896-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE149035_2_v_0_hepacam_human RummaGEO Gene Perturbation Signatures -1.0 null FGFR3_knockdown_34_GDS4454 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.23662 EBF1-22473956-BONE-MARROW-MOUSE ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.80329 RL DepMap CRISPR Gene Dependency 1.0 2.60119 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null E2F6_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7063-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.35636 preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16647 PLIN5_OE_GSE44192_482_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null liminal part of r2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09296 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF217 ChEA Transcription Factor Targets 1.0 null PMC12582692-medi-104-e45093-s001.xlsx-Table_S1-Table_S1_Genetic_instruments_of_plasma_proteins_for_MR_analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null C3A CCLE Cell Line Gene CNV Profiles 1.0 1.3821 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15838 NCIH1693 CCLE Cell Line Gene Expression Profiles 1.0 1.70999 GSE214931_2_v_5_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.940608 GSE184902_4_v_1_adiponectin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03147 RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28543 GSE157555,GSE157556_3_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.67079 lateral dorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19008 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null E2F1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1 Rummagene Transcription Factor Associations 2026 1.0 null NH6 CCLE Cell Line Gene Expression Profiles 1.0 1.60181 CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.27706 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15985 H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142232,GSE142234_0_v_3_gcgr_mouse RummaGEO Gene Perturbation Signatures -1.0 null medial amygdala, posterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27992 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07971 abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.105113 HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46991 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.062745 Rce TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.579 USP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34607 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.91546 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null C5orf22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07882 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02437 H3K27me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2854-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16 Rummagene Transcription Factor Associations 2026 1.0 null GSE218727_2_v_1_zkscan3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE102505_1_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null recurrent infections GWASdb SNP-Phenotype Associations 1.0 0.306163 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.29565 autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.639463 Anterior cingulate area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26755 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KMS11 CCLE Cell Line Gene CNV Profiles -1.0 -1.33166 GSE210101,GSE210114_8_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null SP in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21396 RAJI COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210101,GSE210114_2_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null TRIM24_Deficiency_GDS3087_609_mouse_Hepatocellular carcinoma (HCC) tumors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-4713-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 hsa-miR-16-5p MiRTarBase microRNA Targets 1.0 null GSE152699,GSE152723_0_v_2_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00589 Parabrachial nucleus, medial division, external medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10366 GSE261563_6_v_1_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null BARHL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43048 anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.50204 r2 part of superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74172 GSE235066_7_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ETS2_KD_GDS5040_129_human_H441 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TDRKH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05879 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88238 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41006 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.862315 Parkin_OE_GDS4476_55_human_U87MG GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null layer III of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01492 neuropeptide signaling pathway GO Biological Process Annotations 2025 1.0 null H3K27me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09296 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8667 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.843591 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17638 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.926219 Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.67255 PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC Rummagene Transcription Factor Associations 2026 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49468 liminal part of alar r1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01484 SLITRK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64407 TEAD4 ENCODE Transcription Factor Targets 1.0 null medial amygdala, anterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38027 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00201 Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.3601 OCUM1 DepMap CRISPR Gene Dependency 1.0 2.104 ERICH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28606 neuropeptide signaling pathway GO Biological Process Annotations 2023 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF7 ENCODE Transcription Factor Targets 1.0 null NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887862 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00421 GSE190316,GSE190324_10_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null TC71 CCLE Cell Line Gene Expression Profiles 1.0 2.40872 TRIM28 ChEA Transcription Factor Targets 1.0 null MAX::MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4286 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13284 Lung squamous cell carcinoma_LUSC_TCGA-85-8277-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08454 mRNA cap methyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.965 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 hsa-miR-4504 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GSE197850_4_v_3_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ES8 DepMap CRISPR Gene Dependency 1.0 3.08561 HES1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2926 P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Gut wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.109 496100430_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02664 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23664 MYCN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1793 GAMG CCLE Cell Line Gene Expression Profiles -1.0 -1.95499 SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4672 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 SUPT20H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02135 JHH2 CCLE Cell Line Gene Expression Profiles -1.0 -2.07587 tamoxifen_homo sapiens_gpl570_gds4095 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_5768_KO_Sip1/Nkx21_SRP010804 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.5264 Kidney BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.940602 EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4487 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 CTCF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 182.013 FOXA1-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GATA3-20176728-TSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mantle zone of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09648 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03813 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE202603_3_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -5.9248 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null r2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15313 GSE216273,GSE216292_0_v_8_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41328 BCAT-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22929 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H23 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE111247_0_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null L363 DepMap CRISPR Gene Dependency 1.0 2.41358 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35604 SLC8B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55444 GSE190316,GSE190324_5_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null HT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72438 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.1825 Basket cell_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tubular endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.594 NCIH838 CCLE Cell Line Gene CNV Profiles 1.0 1.35734 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01319 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57267 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.852643 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.599368 GSE101239_3_v_0_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR3-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91848 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.861369 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE195559_3_v_9_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null pontine nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.97714 CTDK-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.549 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.45512 GSE210101,GSE210114_6_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE195568_2_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LOUNH91 CCLE Cell Line Gene Expression Profiles 1.0 1.68366 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5217 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06286 GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE226249_5_v_8_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null A_CA_04_2009_4dayMOI-10^3_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.59598 GSE239844_7_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD Rummagene Transcription Factor Associations 2026 1.0 null reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.918346 KNS81 CCLE Cell Line Gene Expression Profiles 1.0 1.39668 GSE242333_0_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34581 Perturb_8459_KO_SOX9_SRP399992 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3925-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Parabrachial nucleus, lateral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02719 GSE216274,GSE216292_4_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148193_1_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-509-3-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Central amygdalar nucleus, capsular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46802 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.04822 GSE120463_1_v_0_tcf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.335664 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.4199 cellular_component GO Cellular Component Annotations 2015 1.0 null primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.34598 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 647V CCLE Cell Line Gene CNV Profiles -1.0 -2.53849 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3158-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21651 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.96802 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.89805 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05532 Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32993 Anterior cingulate area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94323 hsa-miR-1236 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE239844_11_v_12_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 2.19171 PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51573 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18978 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PU1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE163240_2_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null ERMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78755 KDM4A ENCODE Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4022 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NDUFB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12758 arcuate nucleus of medulla, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.21655 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.352227 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828988 EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5757 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83888 SUM185PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.80144 RNF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37687 reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 mantle zone of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10366 hsa-miR-578 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 all GWASdb SNP-Phenotype Associations 1.0 0.042513 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.841472 Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lysosome LOCATE Predicted Protein Localization Annotations 1.0 null 496100326_TCx_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.47131 NHLH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.5593 superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31225 striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19692 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.995191 PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null WNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48939 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null FIH_Deficiency_GDS3769_511_mouse_Immortalized embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05926 Pyloric cecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.689 HCT116 CCLE Cell Line Gene CNV Profiles 1.0 1.89817 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13515 H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.62267 body height GAD Gene-Disease Associations 1.0 null GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures -1.0 null KMS26 CCLE Cell Line Gene CNV Profiles -1.0 -1.44245 ventrolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.88747 Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142232,GSE142234_0_v_2_gcgr_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE210101,GSE210114_2_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908344 ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.313 Papillary glioneuronal tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.672 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null heart disease GWASdb SNP-Disease Associations 1.0 0.166127 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Accessory olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.549 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31061 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.26753 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.972396 intercalated amygdaloid nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12302 OSC-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE205687_1_v_0_mta1_human RummaGEO Gene Perturbation Signatures -1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87932 CALCOCO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55875 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216988,GSE216989_0_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null DDX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04555 GFOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21385 reticular nucleus of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.49837 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01528 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE111247_0_v_13_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null HS840T CCLE Cell Line Gene Expression Profiles -1.0 -1.45608 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE101239_5_v_0_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null CYP2D6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10062 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.050533 signal transduction GO Biological Process Annotations 2015 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null PDS5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39502 GSE111660_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984509 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887862 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.921248 PMC12754469-ab-25-0159-Supplementary-1.pdf-37-TBX18_TBX18 Rummagene Transcription Factor Associations 2026 1.0 null Brain_CT2_DLNP 93 HuBMAP ASCT+B Augmented with RNA-seq Coexpression 1.0 null PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null RNF146 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70286 Lung adenocarcinoma_LUAD_TCGA-93-A4JO-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-200a TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958818 THY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16057 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.845589 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLEKHG4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72371 CHD2 ENCODE Transcription Factor Targets 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null hsa-miR-3156-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 NCIH2023 CCLE Cell Line Gene CNV Profiles 1.0 1.7366 PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149359_2_v_1_asap2_human RummaGEO Gene Perturbation Signatures 1.0 null LP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.34845 superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8056 OVCA420 DepMap CRISPR Gene Dependency 1.0 2.2034 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.89805 ZBTB11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1286 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE216273,GSE216292_0_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC70 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.98962 GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures 1.0 null Wt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 62.0296 NUDT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10755 Nephronophthisis DisGeNET Gene-Disease Associations 1.0 null OCIM2 DepMap CRISPR Gene Dependency 1.0 10.067 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07561 Perturb_8833_KO_RING1A_SRP345831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19102 L540 CCLE Cell Line Gene CNV Profiles 1.0 1.58086 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.90857 Medial amygdalar nucleus, posterodorsal part, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1618 H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.2618 Orbital area, medial part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37024 ETS2_KD_GSE43459_687_human_H441 lung cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-338-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.32519 lateral septal nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02802 POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4715 organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14947 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null striatal septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1028 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-509-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 UPCISCC111 DepMap CRISPR Gene Dependency 1.0 2.1065 r4 part of lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38951 G402 CCLE Cell Line Gene Expression Profiles 1.0 1.98703 lateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0211 GSE202434,GSE202438_10_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7246 accumbens nucleus, core domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10027 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.01502 Heart Failure dbGAP Gene-Trait Associations 1.0 0.007255 r4 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25102 Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23059 hsa-miR-4263 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE134375_0_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null r1 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77323 H3K27me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HT55 CCLE Cell Line Gene Expression Profiles -1.0 -1.47079 GSE122425_1_v_0_nsun2_human RummaGEO Gene Perturbation Signatures -1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.956125 EPHB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00905 E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE195568_2_v_4_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.864375 ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3286 GSE213410_2_v_3_calcitriol_human RummaGEO Drug Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.954815 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37053 r1 part of vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40123 Ovarian Neoplasm DisGeNET Gene-Disease Associations 1.0 null disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 hypertension GWASdb SNP-Phenotype Associations 1.0 0.65006 Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1379 ventrolateral prefrontal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21304 Functional gastric disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.263 substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.942156 SUM102PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.910056 GSE202434,GSE202438_15_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE111247_0_v_6_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38951 IK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15656 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58595 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.99574 496100432_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18757 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null metabolic GAD High Level Gene-Disease Associations 1.0 0.300704 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.03415 cell part LOCATE Predicted Protein Localization Annotations 1.0 null male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 mantle zone of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84234 RTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89972 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Functional diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.649 SLR25 CCLE Cell Line Gene Expression Profiles -1.0 -1.57987 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Male infertility GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.604576 H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE213228_2_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17497 RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09602 TEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02301 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r5Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14119 disease GWASdb SNP-Disease Associations 1.0 0.040655 GSE202434,GSE202438_9_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.995684 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46103 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null GSE175787_4_v_7_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null 496100408_PCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.55692 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16908 MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19102 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24405 periventricular stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08247 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null GATA6-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11058 GSE111247_2_v_7_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53 Rummagene Transcription Factor Associations 2026 1.0 null RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5302 female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.180937 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32491 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06578 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20661 intermediate stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49484 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.095076 PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13 Rummagene Transcription Factor Associations 2026 1.0 null Anterior cingulate area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28914 HCA-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80357 MRPL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16564 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE202434,GSE202438_8_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.57318 icSARS-Cov_Day1_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.93075 Periventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00589 GSE150055_0_v_1_melphalan_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_3_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13853 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53163 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908344 superficial stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38951 r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58906 Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24063 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.76593 neuroblastoma GAD Gene-Disease Associations 1.0 null superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30497 KDM5B_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung disease GWASdb SNP-Disease Associations 1.0 0.598248 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Banded collagen fibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.839 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.10813 FOXH1-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OTUD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09199 H3K4me1_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null isthmic vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14504 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.26665 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88103 hsa-miR-4753-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ZNF217-24962896-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE242083,GSE242098_2_v_4_med1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE111247_14_v_10_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIB1_KO_GDS2944_555_mouse_Macrophages GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PCSK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0004 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844468 Posterior amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.041 MRRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23491 Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38808 PMC11295044-pnas.2403331121.sapp.pdf-216-ZNF33B_ZNF33B Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOSPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03508 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.829817 hsa-miR-484 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.858087 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03427 PKCTHETA-26484144-CHIP-SEQ-BREAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Ovarian Cysts DisGeNET Gene-Disease Associations 1.0 null PCGF4-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887862 EA-18-FP00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.241027 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06683 GSE157282_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8822763-13293_2022_415_MOESM3_ESM.xlsx-ML_MR_DEG-Gene_name_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null SUM149PT DepMap CRISPR Gene Dependency 1.0 5.32574 Parabrachial nucleus, medial division, medial medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21972 H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null subthalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61157 PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC Rummagene Transcription Factor Associations 2026 1.0 null PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ChIP_SUZ12_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05324 npBAF complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.751 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.1586 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain disease GWASdb SNP-Disease Associations 1.0 0.168537 496100335_PCx_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.90278 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02054 amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11634 FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null male infertility GAD Gene-Disease Associations 1.0 null GSE180185_7_v_1_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_3684_KD_MEX3A_SRP321087 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SW948 DepMap CRISPR Gene Dependency 1.0 3.45332 Rett Syndrome_frontal cortex_GSE6955 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.45507 KYSE70 CCLE Cell Line Gene CNV Profiles -1.0 -1.50531 hsa-miR-4699-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.404082 globus pallidus, external segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45777 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47959 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74172 CHD7 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null fasciola cinerea Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6764 r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.98548 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX11-23321250-Z138-A519-JVM2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null mantle zone of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06599 Central amygdalar nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48875 precentral gyrus, right, superior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.949603 subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.984456 GSE219195_4_v_5_rbm12_human RummaGEO Gene Perturbation Signatures -1.0 null NCIH446 CCLE Cell Line Gene Expression Profiles 1.0 1.90694 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62592 PARP16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40293 NCIH2106 CCLE Cell Line Gene CNV Profiles -1.0 -1.34831 BEN CCLE Cell Line Gene CNV Profiles 1.0 1.9571 K562 DepMap CRISPR Gene Dependency 1.0 3.48895 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02951 GSE121824,GSE121826_0_v_6_scaf8_human RummaGEO Gene Perturbation Signatures -1.0 null GSE181513_2_v_1_usp7_human RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.06383 RARRES1_KD_GDS4818_314_human_SUM149 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null IGROV1 DepMap CRISPR Gene Dependency 1.0 8.05941 rhombomere 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0827 lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.20146 GSE214382,GSE214383_5_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null 22RV1 CCLE Cell Line Gene CNV Profiles -1.0 -1.98898 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.83207 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27956 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.895015 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEF2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1659 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02951 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.0554 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12159 mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1312 Gastric outlet obstruction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.505 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195743_3_v_2_lhx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null SUZ12-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02868 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38951 P300-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCIH2227 CCLE Cell Line Gene Expression Profiles 1.0 1.35977 extracellular region GO Cellular Component Annotations 2015 1.0 null superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39757 superficial stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08618 Perturb_17213_OE_EWSFLI_SRP261076 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.97197 anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07005 Dystroglycan complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.984 PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1 Rummagene Transcription Factor Associations 2026 1.0 null ACHN CCLE Cell Line Gene Expression Profiles 1.0 1.41611 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12056 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4425_KO_Eed_SRP172483 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.4013 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.902905 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12905 GSE202434,GSE202438_15_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5593 mantle zone of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21562 Omphalocele DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.243 principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16761 CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null prion disease GWASdb SNP-Disease Associations 1.0 0.794936 snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.47409 GSE175787_13_v_2_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null r5 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14119 GSE128076_1_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null GNPAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18926 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07971 GSE182770,GSE182784_0_v_1_chd2_human RummaGEO Gene Perturbation Signatures 1.0 null LATS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32614 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.94358 TMEM109 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36795 Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of the basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08283 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33333 H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158743_1_v_2_nfkbia_human RummaGEO Gene Perturbation Signatures -1.0 null PMC4521181-oncsis201520x8.pdf-205-MLXIPL_MLXIPL Rummagene Transcription Factor Associations 2026 1.0 null GSE111247_2_v_6_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null Juvenile absence epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 ATF2 MSigDB Cancer Gene Co-expression Modules 1.0 null GATA3-20176728-TROPHOBLAST STEM CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Ecthyma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.057 intermediate part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84147 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.275181 TAF15-26573619-CHIP-SEQ-HEK293-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OTUD6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26271 Mouse - Motor Cortex - Cross-Species Cluster - Sst+ GABAergic neuron_7 HuBMAP Azimuth Cell Type Annotations 1.0 null TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887862 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.6149 GSE111247_0_v_8_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null LN235 DepMap CRISPR Gene Dependency 1.0 3.19853 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06683 ventral part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03653 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828988 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8964 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02152 Perireunensis nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23606 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62653 r3 part of lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31407 periventricular stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77323 basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17607 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.961439 retropontine reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29885 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.809986 SPG21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5187 GSE205163,GSE205164_3_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02629 GSE235066_4_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null MATK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18347 GSE214382,GSE214383_4_v_2_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null ovarian cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.287235 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.986544 TTC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64935 RWDD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06235 GSE261563_9_v_4_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09718 AR-22383394-PROSTATE-CANCER-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE193258,GSE193259_5_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63 Rummagene Transcription Factor Associations 2026 1.0 null USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.91319 SPRING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03518 GSE111247_0_v_7_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null respiratory system disease GWASdb SNP-Disease Associations 1.0 0.182881 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13559 MYC ChEA Transcription Factor Targets 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43081 NLGN4Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78852 endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46627 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null LC-1-SQ COSMIC Cell Line Gene Mutation Profiles 1.0 null r2 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20222 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null GSE202434,GSE202438_3_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null r2 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75208 congestive heart failure GWASdb SNP-Phenotype Associations 1.0 0.442008 ISTMEL1 DepMap CRISPR Gene Dependency 1.0 7.48344 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.872378 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cancer GAD High Level Gene-Disease Associations 1.0 0.293278 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16996 SOX11 ChEA Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE233647_4_v_6_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null GSE146612_1_v_3_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null Lateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3736 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A0TN-01A-21R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.873049 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59665 RT112 CCLE Cell Line Gene CNV Profiles -1.0 -1.85116 PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null PAPOLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57262 GSE118816_0_v_1_myo1c_human RummaGEO Gene Perturbation Signatures 1.0 null GSE155031_5_v_1_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.886522 GSE210101,GSE210114_4_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GSE111660_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null PAK1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97385 OC314 DepMap CRISPR Gene Dependency 1.0 5.60993 mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.980141 GSE202434,GSE202438_13_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE175787_13_v_6_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE210101,GSE210114_6_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null IL17RD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11588 IRF2BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62422 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null hsa-miR-940 TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 Colon transversum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.607 p4 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.64 layer 3 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2114 ZFP57 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0516 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null prepontine hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04637 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DEAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1946 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.1384 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17762 artery disease GWASdb SNP-Disease Associations 1.0 0.115564 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039602 hsa-miR-542-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 MOLP8 CCLE Cell Line Gene Expression Profiles 1.0 1.64619 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07971 reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045625 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2786 hsa-miR-4643 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.42223 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12942 DDX50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50786 Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01411 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56227 ETV1-20927104-GIST48-HUMAN ChEA Transcription Factor Targets 2022 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05675 GSE138001_0_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.983394 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959507 NCIH2052 DepMap CRISPR Gene Dependency 1.0 2.31012 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.100547 REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828988 H2AFZ ENCODE Transcription Factor Targets 1.0 null KYM1 CCLE Cell Line Gene Expression Profiles 1.0 2.13604 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE242083,GSE242098_3_v_0_med1_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-520d-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.17031 globus pallidus, internal segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36372 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null AR ChEA Transcription Factor Targets 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18739 medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1312 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.287235 GSE111247_2_v_13_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null CAL148 CCLE Cell Line Gene CNV Profiles -1.0 -2.07361 heart failure GAD Gene-Disease Associations 1.0 null H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46338 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3192 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.49198 primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2025 hsa-miR-3169 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10312 Skin - Not Sun Exposed (Suprapubic) GTEx Tissue Gene Expression Profiles 2023 1.0 3.58405 PHETA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61593 ZNF322 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08339 Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_2_v_0_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51496 REC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.38105 NLRP6 inflammasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.532 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548s TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GSE197850_4_v_0_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12056 FOXA2-19822575-HEPG2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28152 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE118816_2_v_3_myo1c_human RummaGEO Gene Perturbation Signatures -1.0 null JAR DepMap CRISPR Gene Dependency 1.0 3.36922 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.3751 SOX2-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE193258,GSE193259_5_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-4789-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950832 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.907977 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE195568_2_v_10_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null NEPRO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1491 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.961176 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34748 extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 STX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04923 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31061 COLO-829 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-188-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 REST-18959480-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE142684_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 MHHES1 CCLE Cell Line Gene Expression Profiles 1.0 1.82516 Neurexophilin InterPro Predicted Protein Domain Annotations 1.0 null brain HPA Tissue Gene Expression Profiles 1.0 1.06165 Interposed nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2154 Femur bone mineral density x serum urate levels interaction GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.830103 r3 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35076 septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59653 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04943 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42369 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-141 TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 SUOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42041 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05629 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r6 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44105 primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21025 ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.829447 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47173 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33756 GSE94814_2_v_3_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NKX2-3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23643 NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SIRT6 ENCODE Transcription Factor Targets 1.0 null Lateral septal nucleus, rostral (rostroventral) part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84456 HMGB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11454 mantle zone of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03653 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.23625 SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08693 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18916 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202434,GSE202438_2_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.60675 GSE159728,GSE159730_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE195743_1_v_4_lhx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null SF767 CCLE Cell Line Gene Expression Profiles -1.0 -1.50939 IM95 CCLE Cell Line Gene Expression Profiles -1.0 -2.74804 LTBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25102 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.53098 Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null intermediate part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09684 NCIH146 CCLE Cell Line Gene CNV Profiles 1.0 1.49367 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.827098 Glomerular filtration rate in chronic kidney disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 r6 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23527 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null subpallial septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65529 ventrolateral prefrontal cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00925 Asthma and eczema GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45458 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02203 PCYOX1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.601 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.878164 F36P CCLE Cell Line Gene CNV Profiles -1.0 -1.79061 RCOR3 ChEA Transcription Factor Targets 1.0 null H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Body Height dbGAP Gene-Trait Associations 1.0 0.913242 GSE164505,GSE164506_3_v_1_indisulam_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HLA-A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54458 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GSE216413_1_v_0_gata3_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBF1-22473956-LYMPHODE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.9106 NF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1402 Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43066 Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3B ChEA Transcription Factor Targets 1.0 null SNU840 CCLE Cell Line Gene Expression Profiles -1.0 -1.61368 SUZ12 ENCODE Transcription Factor Targets 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.01969 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null chemdependency GAD High Level Gene-Disease Associations 1.0 0.293278 PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null hypertension GWASdb SNP-Disease Associations 1.0 0.75112 GSE210101,GSE210114_1_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2996-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain_CT2_DLNP 93 HuBMAP ASCT+B Annotations 1.0 null IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0497 H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870177 PIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23001 TT CCLE Cell Line Gene CNV Profiles 1.0 2.75264 GSE134375_6_v_5_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57267 ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.810392 striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.936627 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.908618 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60491 Mouse - Motor Cortex - Cluster - Pou3f2+ Layer 6 glutamatergic neuron, corticothalamic-projecting HuBMAP Azimuth Cell Type Annotations 1.0 null primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28869 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19114 SBC5 CCLE Cell Line Gene CNV Profiles 1.0 2.09374 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6764 ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7218 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.916235 KYSE150 DepMap CRISPR Gene Dependency 1.0 2.06403 pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.67919 r5 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15313 SW900 CCLE Cell Line Gene CNV Profiles 1.0 1.43969 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.890458 H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HEY DepMap CRISPR Gene Dependency 1.0 3.00775 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.89805 Brain_CT2_Splat 380 HuBMAP ASCT+B Annotations 1.0 null CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.92364 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.847 Muscular dystrophy-dystroglycanopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.336 r6 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09648 HT CCLE Cell Line Gene CNV Profiles -1.0 -2.16502 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16302 496100320_PCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19735 GSE239844_11_v_2_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.920439 GSE224969,GSE224971_0_v_5_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.830839 thoracic cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01327 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23657 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null PIK3CA_mutant_27_GDS4053 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.76663 rostral group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26254 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.59022 intermediate stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12834 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.863492 GSE235066_4_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.71344 MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.914949 Anterior horn cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.525 orbital frontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.929692 HEC1A CCLE Cell Line Gene CNV Profiles 1.0 1.41027 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050557 GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950832 GSE210101,GSE210114_8_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC Rummagene Transcription Factor Associations 2026 1.0 null WDR5-24793694-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null nucleus of the diagonal band, left, vertical division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.52706 hsa-miR-1288 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 granular layer of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09081 GSE195513_0_v_3_cpeb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null r1 part of the 'mesencephalic' trigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38951 Perturb_17214_KD_TRIM8_SRP261076 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.42088 PMC6814198-NIHMS1538462-supplement-2.xlsx-Transitory_415genes-SNAI2_SNAI2 Rummagene Transcription Factor Associations 2026 1.0 null SW900 COSMIC Cell Line Gene Mutation Profiles 1.0 null IGF2BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20298 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.63703 mantle zone of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46174 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.906288 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE216273,GSE216292_0_v_6_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null OVMANA CCLE Cell Line Gene CNV Profiles 1.0 1.82887 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null CTBP2 ENCODE Transcription Factor Targets 1.0 null Human - Motor Cortex - Subclass - Layer 5-6 glutamatergic neuron, near-projecting HuBMAP Azimuth Cell Type Annotations 1.0 null TUHR10TKB DepMap CRISPR Gene Dependency 1.0 3.82289 Contagious pustular dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138001_5_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null ChIP_SUZ12_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ESS1 CCLE Cell Line Gene Expression Profiles 1.0 1.54437 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null GSE148263_6_v_9_trim3_human RummaGEO Gene Perturbation Signatures 1.0 null Semimembranosus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.525 GSE128076_2_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.06916 cardiovascular GAD High Level Gene-Disease Associations 1.0 0.298214 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05608 AP5M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82543 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null G402 CCLE Cell Line Gene CNV Profiles 1.0 1.55991 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050849 NAAA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32005 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22067 GSE216238,GSE216241_0_v_1_tonsl_human RummaGEO Gene Perturbation Signatures 1.0 null primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.35355 PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null Nucleus of the trapezoid body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0965 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.3427 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PFSK1 DepMap CRISPR Gene Dependency 1.0 2.23911 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.39104 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09126 CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050431 parvicellular part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15709 hsa-miR-4662a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 LU65 DepMap CRISPR Gene Dependency 1.0 2.13589 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908344 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01115 plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H2BK20ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE210101,GSE210114_5_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76739 Ovarian Cysts CTD Gene-Disease Associations 1.0 2.88009 GSE153871_1_v_2_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null HCC1143 DepMap CRISPR Gene Dependency 1.0 2.38622 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12232 SLC44A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90578 A_CA_04_2009_4dayMOI-10^4_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.83222 TBP ENCODE Transcription Factor Targets 1.0 null H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.6181 MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.10966 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.975551 MAX_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22847 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14914 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Medial septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15612 Alcohol dependence GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.509691 NCIH1581 CCLE Cell Line Gene CNV Profiles 1.0 1.61948 Perturb_15803_KO_PCM1_SRP170956 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.93462 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-378g TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 TASK1 DepMap CRISPR Gene Dependency 1.0 2.37234 Meier-Gorlin syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.192 KURAMOCHI CCLE Cell Line Gene Expression Profiles 1.0 3.40745 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.01062 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GATA4-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null FARSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34618 lateral habenular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40165 LC4-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXA2 ChEA Transcription Factor Targets 1.0 null RAB3GAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58578 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE174701_1_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Dermal dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.831 SMAD3-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BL70 CCLE Cell Line Gene CNV Profiles -1.0 -1.74845 mood disorder GWASdb SNP-Disease Associations 1.0 0.301086 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.884015 H3K27me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.04572 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32425 Lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51496 YY1 ENCODE Transcription Factor Targets 1.0 null PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null GSE176008_8_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null SPO11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04295 Cervix - Endocervix GTEx Tissue Gene Expression Profiles 2023 1.0 2.47145 GSE142210_4_v_5_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7887-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5044-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOB1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00167 Central amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32082 DACH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45958 hsa-miR-377 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 MYC-19915707-AK7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.866887 G0S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3924 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.44271 U2OS CCLE Cell Line Gene Expression Profiles 1.0 1.46499 hsa-miR-576-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15884 GSE138863_3_v_0_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.67255 GSE126127_0_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null neuropeptide signaling pathway GO Biological Process Annotations 2015 1.0 null 143B CCLE Cell Line Gene Expression Profiles 1.0 1.49923 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LEF1_LEF1 Rummagene Transcription Factor Associations 2026 1.0 null mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20974 19168792-TableS3 GeneSigDB Published Gene Signatures 1.0 null GR MotifMap Predicted Transcription Factor Targets 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.04078 AKIRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05098 stratum oriens of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05117 GSE111660_1_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3061 KDM5B ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.58411 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63 Rummagene Transcription Factor Associations 2026 1.0 null BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE137954_4_v_2_smyd3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3 ChEA Transcription Factor Targets 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04004 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138863_2_v_0_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.330552 cSARS Bat SRBD_48Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.57293 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.666845 HCC1897 CCLE Cell Line Gene Expression Profiles -1.0 -1.92102 H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.854828 Human - Motor Cortex - Cross-Species Cluster - Lamp5+ GABAergic neuron_2 HuBMAP Azimuth Cell Type Annotations 1.0 null NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40532 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GW-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA2, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11566 RUNX2 ChEA Transcription Factor Targets 1.0 null GSE142684_3_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051786 NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.43476 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01484 hsa-miR-3713 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 PIAS1-25552417-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30406 specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.328105 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null SCC4 DepMap CRISPR Gene Dependency 1.0 2.51417 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66095 Metabolite levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIRT6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null kidney GTEx Tissue Gene Expression Profiles 1.0 1.03614 KLF4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE138001_2_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039922 BT549 CCLE Cell Line Gene Expression Profiles 1.0 1.43469 GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039812 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE111247_2_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE195568_1_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40471 Carcinoma, Ovarian Epithelial DisGeNET Gene-Disease Associations 1.0 null H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE174701_1_v_2_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.103222 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 78.3733 Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM200C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65397 GSE221742,GSE221743_1_v_0_sipa1_human RummaGEO Gene Perturbation Signatures 1.0 null pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50188 Perturb_6371_KD_FOXF1_SRP124661 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.02396 Nauplius TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.824 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22228 hsa-miR-4471 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 PEX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17068 ChIP_SUZ12_16625203 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2279 CCLE Cell Line Gene Expression Profiles 1.0 1.80846 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052199 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33972 r1 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61286 H2BK12ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7148 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00589 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.726687 GSE128333_4_v_0_tcf4_human RummaGEO Gene Perturbation Signatures 1.0 null GSE202434,GSE202438_13_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Medial amygdalar nucleus, posterodorsal part, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35288 Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.837066 r6 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1132 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6116 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10479 163 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.848 ELF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2971 GSE193258,GSE193259_2_v_3_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null periventricular stratum of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36184 spleen GTEx Tissue Gene Expression Profiles -1.0 -0.948843 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050507 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.96593 midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15088 H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE111247_14_v_3_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST-18959480-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null striatal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21602 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.880551 ACCMESO1 CCLE Cell Line Gene Expression Profiles 1.0 2.02999 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null GSE205163,GSE205164_2_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.52446 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.867945 GSE139016_0_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null GSE210101,GSE210114_2_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PMC10679662-mmc2.xlsx-NC-D3-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null TSC22D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19865 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1311 GSE129241_4_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Parabrachial nucleus, lateral division, dorsal lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31407 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MET_knockout_248_GDS3148 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.80211 mania GWASdb SNP-Phenotype Associations 1.0 0.509159 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.570703 FOXM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04869 EARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67214 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9846 DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -2.37133 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19081 Enteric plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.266 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE187006_3_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null NANOG-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE163240_3_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null pontine reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27104 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49694 GSE190316,GSE190324_6_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null lateral medullary reticular group, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63821 GI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64119 Perturb_8659_KO_TP53_SRP251281 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Primary somatosensory area, barrel field, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05068 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63489 nBAF complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.669 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51581 Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36184 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.65792 PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8 Rummagene Transcription Factor Associations 2026 1.0 null CDC25C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42861 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.040651 mantle zone of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67725 regulation of cellular process GO Biological Process Annotations 2015 1.0 null orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12241 primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.48877 PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0325 Primary somatosensory area, barrel field Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08966 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RCOR3-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null amygdaloid complex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10398 H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.23625 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26684 GSE205163,GSE205164_1_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.956646 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.861509 624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46519 Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Chagas disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.046 CMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null intermediate part of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37252 Perturb_8992_KD_PAX9_SRP407074 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.1409 NSMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09133 Perturb_8481_KD_DAP5_SRP073613 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.99914 POLR2AphosphoS5_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TIMM10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31829 Dinoflagellate cingulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.903 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.66609 reticular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.26283 PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null Lateral septal nucleus, caudal (caudodorsal) part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24457 GSE142210_4_v_6_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null HCC1937 CCLE Cell Line Gene Expression Profiles -1.0 -2.46766 SIN3A ENCODE Transcription Factor Targets 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain - Amygdala GTEx Tissue Gene Expression Profiles 2023 1.0 2.71568 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.62032 SAP30 ENCODE Transcription Factor Targets 1.0 null FBH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5136 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29889 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02939 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43215 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.993902 inferior frontal gyrus, orbital part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.870495 Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null throat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.328262 COGN305 DepMap CRISPR Gene Dependency 1.0 2.06144 Perturb_14539_KO_Kras_SRP311976 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.43512 GSE148263_6_v_0_trim3_human RummaGEO Gene Perturbation Signatures 1.0 null 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.74755 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.82839 HEC1B DepMap CRISPR Gene Dependency 1.0 4.19765 PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3625 ZBTB7B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9528 GA-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T2-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCFL5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.1484 intermedioposterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02311 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.35202 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06903 Cystic Fibrosis_Lung_GSE3100 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.41767 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Megacolon DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.298 RBBP5 ENCODE Transcription Factor Targets 1.0 null abnormality of cardiovascular system physiology GWASdb SNP-Phenotype Associations 1.0 0.136179 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.92097 GSE233647_2_v_3_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.7256 MHHES1 CCLE Cell Line Gene CNV Profiles 1.0 1.40501 YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CIAO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16835 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950832 CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2939 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950832 hsa-miR-3919 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.132926 H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34088 MYC ENCODE Transcription Factor Targets 1.0 null GSE213228_1_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null rostral group of intralaminar nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01257 CENPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12943 Pyloric stenosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.657 TE1 CCLE Cell Line Gene Expression Profiles -1.0 -1.65104 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.808506 ZBED2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.67 GSE111247_2_v_8_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null pontine nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.874019 Lung adenocarcinoma_LUAD_TCGA-93-A4JN-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular part of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85291 hsa-miR-3647-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 SUZ12-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE202434,GSE202438_7_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null RGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3164 Lateral septal complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60587 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.958872 dorsal peduncular cortex, periventricular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08213 Prelimbic area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03693 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23291 H2803 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NHEJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0555 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00881 cerebellar cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.68957 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04066 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08882 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22623 Corpus Luteum Cyst DisGeNET Gene-Disease Associations 1.0 null Catecholaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.118 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28243 GSE102675_3_v_0_atf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61E-01A-22R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE248045,GSE248046_4_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dolichol-phosphate-mannose synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.063 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.13725 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.16156 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.878356 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60607 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17294 H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE125862_2_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73132 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A3U7-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -2.41601 hsa-miR-4501 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 POLR2A ENCODE Transcription Factor Targets 1.0 null Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.825216 hsa-miR-466 TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 EFE184 DepMap CRISPR Gene Dependency 1.0 3.92677 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28468 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.5004 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8326-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUZ12-16625203-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE210101,GSE210114_8_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null STAT3-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-3155b TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 GTF2F1 ENCODE Transcription Factor Targets 1.0 null ChIP_K27me3_17603471_mouseNPC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null intermediate stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63651 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.37079 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.7184 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908344 NMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-4330 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.85501 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.83162 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MAFK_MAFK Rummagene Transcription Factor Associations 2026 1.0 null Alloimmunization response to pregnancy (HLA class I) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 DRGX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40953 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE175787_5_v_6_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.27358 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10861 callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87035 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23664 induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80734 H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE221742,GSE221743_1_v_2_sipa1_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.44267 PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null PRICKLE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24739 BACH1 ENCODE Transcription Factor Targets 1.0 null LU-139 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR Rummagene Transcription Factor Associations 2026 1.0 null parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.920514 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.82705 Perturb_6199_KO_Elp3_SRP065804 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.25843 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00201 r1 part of superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50143 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1219 cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 TAF1 ENCODE Transcription Factor Targets 1.0 null abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35092 anteroventral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.987812 HDAC2 ENCODE Transcription Factor Targets 1.0 null FGFR3_knockdown_173_GSE41035 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.23657 hsa-miR-323b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 r3 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.5279 P300-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Subceruleus nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21972 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.457864 nervous system disease GWASdb SNP-Disease Associations 1.0 0.055692 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19778 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.69069 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC3898078-1471-2164-15-40-S1.pdf-59-NR2F1_NR2F1 Rummagene Transcription Factor Associations 2026 1.0 null BRCA1 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE156923_2_v_3_rbmx_human RummaGEO Gene Perturbation Signatures -1.0 null PRC_Partial Depletion_GDS3531_563_human_U2OS cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null depression GWASdb SNP-Phenotype Associations 1.0 0.36466 Lung adenocarcinoma_LUAD_TCGA-MP-A4TC-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138001_0_v_3_rorb_mouse RummaGEO Gene Perturbation Signatures -1.0 null Autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.122 TRIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25765 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null SUM52PE DepMap CRISPR Gene Dependency 1.0 3.16272 pallidal septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46174 GSE101112_0_v_4_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.98548 hsa-miR-577 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205730,GSE205731_2_v_3_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null male infertility DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202434,GSE202438_6_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RERFLCSQ1 DepMap CRISPR Gene Dependency 1.0 7.65682 Lateral septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66121 TCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06986 HDAC1_KO_GDS2294_67_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40532 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00951 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.062558 medial mammillary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.837717 r2 part of the ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16908 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60962 H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4418 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.29565 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE162015_2_v_0_nfkb1_human RummaGEO Gene Perturbation Signatures 1.0 null Pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.102 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5706 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.89805 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40344 GSE158458_2_v_3_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.26594 NCIH1838 CCLE Cell Line Gene CNV Profiles -1.0 -1.74768 CMK COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE146612_1_v_0_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13284 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908344 superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28109 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6385-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.58433 Hypertrophic pyloric stenosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.828 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100393_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01471 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6384-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neuroblastoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Anterior cingulate area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48959 developmental GAD High Level Gene-Disease Associations 1.0 0.293278 GSE121824,GSE121826_0_v_3_scaf8_human RummaGEO Gene Perturbation Signatures -1.0 null neck TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.280364 GSE231648_0_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE202434,GSE202438_12_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null TBC1D20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36407 GSE175787_13_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-1 MiRTarBase microRNA Targets 1.0 null Neuroblastoma dbGAP Gene-Trait Associations 1.0 0.576793 GSE142684_2_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Anterior cingulate area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26236 BMPR1A_knockout_222_GSE48092 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -0.94307 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3155 TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 GSE175787_5_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78452 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sepsis_Splenocyte_GSE4479 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.41505 GSE163240_3_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null Neurotoxicity Syndromes CTD Gene-Disease Associations 1.0 1.03084 ZNF143 ENCODE Transcription Factor Targets 1.0 null H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CCT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15969 H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.980657 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52894 Cell surface furrow COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.886 SNU626 CCLE Cell Line Gene Expression Profiles 1.0 2.25262 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39714 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63792 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.66312 parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.79694 HPAFII DepMap CRISPR Gene Dependency 1.0 5.4363 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47008 H3K27me3_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RT11284 CCLE Cell Line Gene CNV Profiles -1.0 -1.4737 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5845 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.055828 Sarcoma_SARC_TCGA-KD-A5QS-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TOV112D DepMap CRISPR Gene Dependency 1.0 2.90512 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16903 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null medial part of r1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06599 HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Nemaline myopathy 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.24 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUZ12-16625203-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41241 mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13202 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null STK11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10151 496100316_TCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.9781 mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80472 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.51056 nerve GTEx Tissue Gene Expression Profiles -1.0 -1.5599 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.58528 ZMPSTE24_Deficiency_GDS3775_506_mouse_Embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.06705 posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.913928 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80292 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039984 ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35627 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12162 A172 DepMap CRISPR Gene Dependency 1.0 6.84035 Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Enteric nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.988 GSE158458_2_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K56ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFYC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26457 GSE111660_1_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100305_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03088 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.13457 Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26868 WASHC2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21047 GSE101239_4_v_1_valproic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null BICR16 DepMap CRISPR Gene Dependency 1.0 2.51985 GSE102505_1_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null HDAC6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE235066_7_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null A-CA-04-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.45081 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.997 H3K4me1_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NDUFV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14901 hsa-miR-513a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE226249_5_v_4_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null lateral septal nucleus, intermediate part, periventricular Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06467 dorsolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08782 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC38 DepMap CRISPR Gene Dependency 1.0 3.70349 Perturb_4414_KO_Eed_SRP172483 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.63455 LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.934268 GSE181513_0_v_1_usp7_human RummaGEO Gene Perturbation Signatures -1.0 null PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6741 Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 1.0435 LIPE_KO_GDS1318_501_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null orbital frontal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.941534 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6873-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.01163 hsa-miR-1276 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE193258,GSE193259_9_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null PATU8988T DepMap CRISPR Gene Dependency 1.0 2.86195 Esophagus - Muscularis GTEx Tissue Gene Expression Profiles 2023 1.0 4.2082 H2BK20ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EW22 DepMap CRISPR Gene Dependency 1.0 2.20117 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17762 Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF4A ChEA Transcription Factor Targets 1.0 null SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FAM236B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07104 posterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06926 lytic vacuole LOCATE Predicted Protein Localization Annotations 1.0 null A172 CCLE Cell Line Gene Expression Profiles 1.0 2.65489 SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.867433 cingulate gyrus, parietal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.857496 Anterior cingulate area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20986 intermediate stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08283 19168792-TableS2 GeneSigDB Published Gene Signatures 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.24859 MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null mammarygland.lact. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23055 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.917382 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19786 H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15631 biological_process GO Biological Process Annotations 2015 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11816 PBX1 ChEA Transcription Factor Targets 1.0 null mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62805 hsa-miR-625 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Neuroblastoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KATOIII CCLE Cell Line Gene CNV Profiles -1.0 -1.48135 IPO7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99898 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ovary HPA Tissue Gene Expression Profiles 1.0 1.54038 MIDEAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40287 hsa-miR-548m TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE157555,GSE157556_4_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZMAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22907 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.901427 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TEAD4_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.997055 vascular disease GWASdb SNP-Disease Associations 1.0 0.082962 SUZ12-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Dorsal premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09856 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08494 mantle zone of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09296 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88033 PL4 DepMap CRISPR Gene Dependency 1.0 5.68659 r4 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19212 r3 part of magnocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00589 urinary bladder HPA Tissue Protein Expression Profiles 1.0 1.33703 KYSE270 CCLE Cell Line Gene CNV Profiles 1.0 1.79817 H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28477 congestive heart failure GWASdb SNP-Disease Associations 1.0 0.51817 pontine reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1428 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE180185_9_v_10_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE202434,GSE202438_3_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Supplemental somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15484 Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.8514 CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 1.47257 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null FU97 COSMIC Cell Line Gene Mutation Profiles 1.0 null E2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7471 Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral septal nucleus, intermedio-intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66964 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Medial cortex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.661 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.953918 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55366 GSE214382,GSE214383_6_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.588 H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CLCN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14328 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A460-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04636 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23331 periventricular stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10097 ZBTB14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6081 SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE231648_0_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1105 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63792 SUZ12 ChEA Transcription Factor Targets 1.0 null PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-3117-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mantle zone of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25102 Hydroxykynureninuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.708 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.56277 SDR39U1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03966 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844468 hsa-miR-3177-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 Grm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.506 CP in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.854692 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.33978 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH211 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE184902_4_v_1_adipor1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE138863_2_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null GSE203308_9_v_10_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Vestibular nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02404 GSE149760_3_v_1_elof1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE195568_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null breast cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.4973 SNU119 CCLE Cell Line Gene CNV Profiles 1.0 2.14646 hsa-miR-1248 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839923 posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64999 Primary somatosensory area, barrel field, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04576 SENP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26871 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25931 GSE239844_11_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.980858 H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE210101,GSE210114_4_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CFTR_Deficiency_GDS1843_191_mouse_Lungs - Animals examined at 3 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3525 GSE163240_2_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-3154 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19676 MRPL53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06895 bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.509159 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70169 JL1 CCLE Cell Line Gene Expression Profiles 1.0 1.75465 AMOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07831 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4277 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35076 H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null raphe nuclei of medulla Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.924963 USF2 ENCODE Transcription Factor Targets 1.0 null METTL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08327 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1622 disease of mental health GWASdb SNP-Disease Associations 1.0 0.043955 Nucleus x Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90549 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.79896 Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX11-23321250-Z138-A519-JVM2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10591879-NIHMS1933918-supplement-2.xlsx-Down_in_NMR_OPC_differentiation-EGR1_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3327 reproduction GAD High Level Gene-Disease Associations 1.0 0.295739 MON DepMap CRISPR Gene Dependency 1.0 8.55414 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JDP2_JDP2 Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35947 MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05629 CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14538_KO_Ehmt2_SRP311976 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.51939 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.89805 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.836966 Kidney_CT1_Connecting Tubule Intercalated Cell Type A HuBMAP ASCT+B Annotations 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38762 JMSU1 CCLE Cell Line Gene CNV Profiles 1.0 1.84898 WM88 CCLE Cell Line Gene CNV Profiles 1.0 1.66597 GSE200502_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE125862_2_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null E2F6 ENCODE Transcription Factor Targets 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44372 Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE102675_2_v_1_atf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null intermediate stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00299 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SOX2 ChEA Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null p2190 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.522 MOGGCCM CCLE Cell Line Gene Expression Profiles 1.0 1.42869 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02954 GSE101239_4_v_6_valproic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30385 THOC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3286 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9247951__F3 PFOCR Pathway Figure Associations 2024 1.0 null posteroventral (inferior) parietal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.01811 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV362 CCLE Cell Line Gene Expression Profiles 1.0 1.38519 GSE195568_1_v_10_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null NFKB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38388 mantle zone of p1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10366 Lung adenocarcinoma_LUAD_TCGA-55-7726-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAP3K1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90093 GSE146687_2_v_5_eribulin_human RummaGEO Drug Perturbation Signatures -1.0 null mediodorsal nucleus of thalamus_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.869744 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_15083_KD_Nsd1_SRP354984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.9381 doxorubicin_homo sapiens_gpl6947_gse25741 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9397 Brain_CT2_Splat 380 HuBMAP ASCT+B Augmented with RNA-seq Coexpression 1.0 null HEC1 DepMap CRISPR Gene Dependency 1.0 2.93128 Emphysema annual change measurement in smokers (percent low attenuation area) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.704576 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.59878 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.938774 Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1028 lateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1 ChIP_RCOR3_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null kidney HPA Tissue Gene Expression Profiles 1.0 1.19273 Achalasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.313 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.837922 SUZ12-18974828-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.845717 STAT3 ChEA Transcription Factor Targets 1.0 null FOXA1-25552417-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null YT COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828988 GSE235066_4_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null digits BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.964397 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_H3K27me3_17603471_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.14044 REST ChEA Transcription Factor Targets 1.0 null psn1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.601 TAF7_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD4-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null r2 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18513 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93189 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null CHAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51287 GSE149901_2_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.59045 hsa-miR-4768-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53621 outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29099 FGF23_OE_GDS3361_493_mouse_kidney GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1808 amygdaloid complex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31132 HARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02445 RPS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52788 r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23098 Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00006 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.05416 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.04004 amygdalo-striatal transition Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35906 SUZ12-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22625 H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VG-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gastroparesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.307 Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4851 SLC25A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88864 RNF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18944 PMC5259899-13287_2016_455_MOESM2_ESM.xlsx-Down-regulated-Supplementary_Table_S2_Down-reguated_genes_expression_in_MESP1_negative_cells_MESP1 Rummagene Transcription Factor Associations 2026 1.0 null GSE153871_1_v_3_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19952 ZNF883 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00394 JL1 CCLE Cell Line Gene CNV Profiles 1.0 1.57222 dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.76291 Kidney_CT1_Connecting Tubule Intercalated Cell Type A HuBMAP ASCT+B Augmented with RNA-seq Coexpression 1.0 null i10 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.237 496100334_PCx_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12807 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78452 GSE148494,GSE182513_1_v_0_hoxd13_human RummaGEO Gene Perturbation Signatures -1.0 null Neurexophilin/NXPE InterPro Predicted Protein Domain Annotations 1.0 null NCIH2227 CCLE Cell Line Gene CNV Profiles 1.0 2.28156 planum temporale, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.830269 ChIP_EZH2_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HUH7 DepMap CRISPR Gene Dependency 1.0 3.92588 H3K9me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE126345_9_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null Anterior cingulate area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29396 Parabrachial nucleus, lateral division, ventral lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26035 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06437 H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840203 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48108 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GSE70935_2_v_4_cyfip1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.50393 cd8.Tcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.984568 CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.901087 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2079 mantle zone of r5Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15313 posterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02659 hsa-miR-1245b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42211 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_9_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02868 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.81681 SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.855142 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09857 lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14689 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3988 lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24378 15985538-TableS1 GeneSigDB Published Gene Signatures 1.0 null SF126 CCLE Cell Line Gene CNV Profiles -1.0 -1.62296 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE149901_3_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-524-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 H4K91ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null embryonic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.557661 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06825 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7831-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3714 TargetScan Predicted Conserved microRNA Targets 1.0 0.389112 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2BK120ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.993743 SRF_KO_GDS3732_148_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE231648_1_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null PECAPJ34CLONEC12 CCLE Cell Line Gene Expression Profiles -1.0 -2.27014 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null subthalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06713 GSE142210_4_v_10_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42231 496100338_HIP_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.61118 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69719 hsa-miR-3692 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887862 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic delta cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.771 superficial stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31407 Lung adenocarcinoma_LUAD_TCGA-91-6829-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.8285 H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.856606 CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null r6 part of ventral gigangocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80075 Primary somatosensory area, barrel field, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34588 DSTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30184 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KIF13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18431 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE195743_3_v_4_lhx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE210101,GSE210114_6_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.974924 FOXA1 ENCODE Transcription Factor Targets 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43664 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31354 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null posteroventral (inferior) parietal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927787 PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-443-ZNF280B_ZNF280B Rummagene Transcription Factor Associations 2026 1.0 null alar part of terminal hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1 MIR34_OE_GDS2755_645_human_HCT116 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OCT4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H345 COSMIC Cell Line Gene Mutation Profiles 1.0 null JMSU1 CCLE Cell Line Gene Expression Profiles 1.0 1.55531 superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2791 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22501 TRAPPC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11806 GSE233647_4_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null UBE2E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12001 Parabrachial nucleus, medial division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34509 g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null hsa-miR-4540 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Anterior olfactory nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22672 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21098 ovary GTEx Tissue Gene Expression Profiles 1.0 1.56846 superficial stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14119 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5858 vacuole LOCATE Predicted Protein Localization Annotations 1.0 null GSE176008_0_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80472 GSE239844_11_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null substance-related disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 intermediate stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44228 TRAPPC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04592 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050507 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66308 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE190316,GSE190324_1_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-335 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE175787_5_v_2_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27959 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.52999 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.83678 NUDT12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09379 arcuate nucleus of medulla, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.69275 Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Myenteric plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.276 AGAP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60411 IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2237 SKES1 CCLE Cell Line Gene Expression Profiles 1.0 1.55571 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30457 POU2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03724 Neuronal dense core vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.297 MED7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46885 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.868157 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r6 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14119 GSE112714_2_v_3_ctnnb1_human RummaGEO Gene Perturbation Signatures -1.0 null lateral septal nucleus, intermedio-dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37107 layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27833 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.508244 r8 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08963 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA2-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.066 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lissencephaly 9 with complex brainstem malformation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.35 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.07368 recurrent viral infections GWASdb SNP-Phenotype Associations 1.0 0.691208 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24883 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887862 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null ChIP_REST_18959480 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Hirschsprung's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.359 Bimiralisib_A-172 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0173744