association	dataset	threshold value	standardized value
Exudative vitreoretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06657
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76977
Amelogenesis imperfecta type 1G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ameloblastic layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.638
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.586356
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85458
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50642
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8566
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10008
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19185
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28941
FAM86B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23723
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68669
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0711
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98686
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83768
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
DNAAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65061
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71508
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05967
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28035
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39692
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
HGF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3149
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4352
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9902
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10606
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85374
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
enlarged thymus	IMPC Knockout Mouse Phenotypes	1.0	null
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
USP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94783
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93778
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96336
Ameloblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
Mucopolysaccharidosis IVA	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.239
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3318
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
Jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
Mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79533
GSE249146_2_v_1_dusp6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79176
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9709
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of biomineral tissue development	GO Biological Process Annotations 2025	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
Junctional epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.092
ZC3H12D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61274
PMC8530322-pone.0258316.s002.xlsx-GG_778_TH17-AA_778_TH17-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61083
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.64
SERPINF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33778
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77615
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tooth ankylosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
Dental pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48831
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1313
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9318
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32813
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03175
BABAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23655
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46264
Inner dental epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174383_6_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
EVX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94143
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23241
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97295
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50494
NCOA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59186
Tooth agenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18736
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24834
ARID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11085
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.978747
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.231
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2192
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42339
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94046
Oral epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39032
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90418
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90259
positive regulation of developmental process	GO Biological Process Annotations 2025	1.0	null
Dental enamel hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.768
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305858
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79085
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00867
ENSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95037
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73878
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78715
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02985
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54041
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17454
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49745
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54086
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tooth disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
B3GNT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79999
Linear skin defects with multiple congenital anomalies 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
Gingival overgrowth	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cementum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23411
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93849
JAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02177
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01986
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8973
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81917
increased circulating alkaline phosphatase level	IMPC Knockout Mouse Phenotypes	1.0	null
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38803
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8519
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
GSE101336_1_v_2_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232564,GSE232566_3_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91832
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8924
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69398
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95509
HYCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
SEC16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97598
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36481
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
Stratum intermedium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.514
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88849
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.747
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41985
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80409
KLC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85579
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82402
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38198
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
Amelogenesis imperfecta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.758
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52389
chr4_75562025_C_T_b38	GTEx eQTL 2025	1.0	3.53976
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91819
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53761
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33124
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
positive regulation of biomineral tissue development	GO Biological Process Annotations 2025	1.0	null
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.89
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25405
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3954
Dentin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.234
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03287
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01107
RHBDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29851
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
Dental enamel hypoplasia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08695
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9362
Geleophysic dysplasia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48315
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
NSDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02573
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00749
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31981
TOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11769
Lens epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96322
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24027
UBALD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87046
ZNF415	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93936
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4481
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
GSE210718_1_v_0_shmt2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2307
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56531
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92297
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62004
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.3213
IFITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60253
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74122
Periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4616
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28264
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0558
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
CPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92287
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2239
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8836
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
MTMR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84291
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Heimler syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23508
Mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.162
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
Df	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
Periodontal ligament cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5714
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01003
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50213
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3311
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30539
PMC12496171-mmc4.xlsx-STable3_CDX1_motif_methylation--Symbol_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10443
Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.66
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
Laminin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.412
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64845
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93614
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE73628_1_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08599
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
PAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64186
Periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5595
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26374
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97339
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
abnormal spleen morphology	IMPC Knockout Mouse Phenotypes	1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233902
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2693
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6887
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86404
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9647
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02736
CUL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33766
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98406
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of tooth mineralization	GO Biological Process Annotations 2025	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4326
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26922
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-03-PW00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202435
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20752
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30859
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17029
HNF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92223
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8697
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dentin dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07312
TM7SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76279
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
Chondrogenic MCT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.259
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16806
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34926
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01492
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32525
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38815
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2992
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94119
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98278
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91033
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23616
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2033
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76832
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18218
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
CREM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28156
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90828
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69721
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tooth bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15243
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8018
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.827141
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83439
Gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76293
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90685
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2045
GSE196259_1_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39741
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99414
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44585
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54736
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98126
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4404
PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-TF_Activity_Genesets-Chu_GATA3__UP_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80208
GSE241847_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20854
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05386
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5372
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9209
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	1.82149
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.30307
Lens epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77238
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
GSE201239_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38826
SLC2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47509
BRI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44594
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42218
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARL2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67186
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22601
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	3.14581
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Testicular germ cell cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01083
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.916
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21536
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63333
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05459
Colonic mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72762
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09568
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.133
GSE163884_1_v_0_sumo2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9188
Gingival fibromatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63981
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9802
PAX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00512
Tooth germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.558
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88537
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
SNU-182 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9171
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26855
CTDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15524
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27646
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1377
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2944
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5025
Mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5644
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88272
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dental pulp disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
Inner medullary collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50364
Amelogenesis imperfecta hypomaturation type 2A3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.882
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.682
Gingival cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67732
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58192
GSE174383_6_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.448
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
Amelogenesis imperfecta type 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.182
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9638
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7718
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9041
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92764
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
Alveolar bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.406
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.827141
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0145
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29155
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8066
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
KCNF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59989
C9orf72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85933
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
Amelogenesis imperfecta type 1J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.745
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
abnormal tooth morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91655
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01197
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28421
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5595
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9323
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.33992
Nance-Horan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
HLE-B3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
Intestinal mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11228
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
Gingival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2082
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71279
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6983
Parkinson's disease (motor and cognition)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39567
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74349
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3195
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Amelogenesis imperfecta	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Enamel epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.847
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53035
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05289
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCWH syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
HEXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26687
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9167
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7983
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43065
Trichodontoosseous syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.262
IDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88101
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18147
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98643
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1826
Developmental and epileptic encephalopathy 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
Gingival fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85074
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6282
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48574
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30624
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94682
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1925
Exudative vitreoretinopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.144
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79567
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60161
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06846
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9437
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
Amelogenesis imperfecta hypomaturation type 2A2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
STAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31086
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70632
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314255
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Vitamin D-dependent rickets type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
NA-16-OJ70_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313551
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2003
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48622
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.33992
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43507
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89388
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1772
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68763
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.586356
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94831
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0803
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
abnormal skin morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22108
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24293
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.33992
Vesiculobullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34906
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0208
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08641
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22616
FAM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85509
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20991
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99536
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30763
RXRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.278
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2086
Dentin sensitivity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
Epibranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24077
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96023
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19424
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
MLS syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
RPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32931
Outer dental epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3729
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kohlschutter-Tonz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.808
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9073
PRMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05195
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17944
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
ZNF570	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58983
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48277
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50904
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5781
Dentinogenesis imperfecta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
Immunodeficiency 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.355
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64818
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12496171-mmc4.xlsx-STable3_CDX1_motif_methylation--GeneID_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93094
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39605
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
GPX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4158
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59519
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03698
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92254
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
GSE96641_5_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5039
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08002
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68554
BB-44-SX65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232067
ARAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14169
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91791
PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58128
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.087
ART5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40507
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79688
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.827141
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0037
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44784
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0963
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61871
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24605
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7311
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69657
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
ZZEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0377
chr4_75559326_G_A_b38	GTEx eQTL 2025	1.0	1.12299
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85922
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5366
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6068
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04796
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8269
AGFG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37219
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2647
AGPAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80033
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0547
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7551
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65078
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206385
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
GPR27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61901
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98051
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6947
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.985
GRB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63242
SYNCRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98161
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0977
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
ZFPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22927
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98339
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07547
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Teeth hard tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
Osteogenesis imperfecta type 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89746
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14911
STAMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16019
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12077596-NIHMS2076735-supplement-3.xlsx-ATAC_RNA_SFPQ_TFE3-WT_dn-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
Gonadal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.62336
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45626
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
HOXD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61483
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06658
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9295
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55441
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary hypomagnesemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
Periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
ARHGAP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2901
C4orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63872
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73527
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.827141
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
ATP5MK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1848
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32364
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
Developmental and epileptic encephalopathy 93	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9594
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
GSE211177,GSE211178_8_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36396
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16829
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88499
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34126
PRRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03815
Dental follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43353
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69278
Incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.173
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67445
Amelogenesis imperfecta type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223564
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93669
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77982
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08096
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54616
SLC27A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
MAPK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4306
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92715
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47949
HMGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80898
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70863
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61421
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06672
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238712
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07526
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
C2orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9282
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2239
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30471
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61263
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Split hand-foot malformation 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
abnormal thymus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3641
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33987
Amelogenesis imperfecta type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.673
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.884
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0844
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72303
Dental pulp calcification	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99969
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83834
Renal hypomagnesemia 5 with ocular involvement	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
Teeth hard tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.695
Dental plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32192
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.89251
Immunodeficiency 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63647
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45258
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3007
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78639
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26807
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61813
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71403
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.285
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1016
PDXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5207
APPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13722
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.09
Mandibular incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.26
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.184
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17244
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95573
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72461
NDUFV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47421
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83122
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
abnormal digit morphology	IMPC Knockout Mouse Phenotypes	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7511
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83335
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5633
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56087
Ectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Loeys-Dietz syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SFXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97555
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44875
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11101
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46821
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GDPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.66328
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11529
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18763
RETREG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51505
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14585
GSE201042_2_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3677
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6137
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77508
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
TST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67769
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56106
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95018
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20717
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37874
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37152
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80627
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8757
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
Dental papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
PMC10879698-mmc1.pdf-4-FOXO4_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73135
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79059
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22128
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39246
STMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32284
GSE205913_1_v_0_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
INTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33066
ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
GSE192663_1_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24042
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98488
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5608
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46028
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81752
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3147
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48908
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31037
GSE181431_0_v_1_calr_human	RummaGEO Gene Perturbation Signatures	1.0	null
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94082
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2959
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
PPP1R14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61701
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31087
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
ZNF528	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60452
positive regulation of enamel mineralization	GO Biological Process Annotations 2025	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.605
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85145
CARHSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15493
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73681
AP3M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44075
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6809
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46343
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28438
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
EYA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91784
PHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27313
g.8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
TRUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89187
LCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76563
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83656
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-45-AA67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221119
SNU-398 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0583
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.945
Tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.43
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
ACSM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13837
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62038
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.285
regulation of enamel mineralization	GO Biological Process Annotations 2025	1.0	null
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92717
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4422
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15535
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4509
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44223
Dental fluorosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
T cell and NK cell immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7472
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98975
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53493
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94864
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75306
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88456
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95296
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79293
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.586356
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7337
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2411
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08196
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04598
Acn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fissured tongue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59395
Gingivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1475
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93785
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83135
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70836
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54051
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90457
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27793
Invertebrate mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.244
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23769
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2363
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47886
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
NFE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44945
KPNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.257
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86281
Odontoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.762
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27519
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82867
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51082
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69499
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9343
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3575
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22136
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
MMP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88593
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
Testicular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TXNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78441
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36677
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39932
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NPIPB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31099
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9932
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4537
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75402
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70376
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1939
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8119
NQO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80167
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26915
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7331
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9643
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6417
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32962
Oculodentodigital dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
FAHD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.029
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96584
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21566
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56702
Stellate reticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11486
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7444
MXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40061
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65157
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82255
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92973
SPATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99387
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66477
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32092
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61215
PWWP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60301
Jalili syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.313
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.827141
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44342
Mouth disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.75
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37544
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48078
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67524
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36244
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0715
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5748
HSFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88967
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54858
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39461
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7683
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27414
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0215
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.063
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89707
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
HK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81977
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12685
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.971
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78605
Mucopolysaccharidosis IV	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
GSE173201_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18045
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70752
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary failure of tooth eruption	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290104
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76724
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brachyolmia-amelogenesis imperfecta syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60687
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66024
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56874
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220753
SEPTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9302
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63321
TEX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41595
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
GSE212074_0_v_1_pus1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dental caries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5134
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6905
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66414
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80217
GSE174383_4_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7486
Atf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6727
Amelogenesis imperfecta hypomaturation type 2A5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.044
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60224
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4586
NUDT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70398
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49197
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58168
Rapp-Hodgkin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44053
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7622
NKAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47414
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.58071
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
HFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70783
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44212
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
Subjective response to lithium treatment in bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
ADAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93869
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88793
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32644
TDRD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16568
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
Chondrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
Testicular cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.379
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56861