association	dataset	threshold value	standardized value
neurological system process	GO Biological Process Annotations 2015	1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Oily fish consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
Lung squamous cell carcinoma_LUSC_TCGA-21-1077-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.4963
ICC15	DepMap CRISPR Gene Dependency	1.0	2.38169
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.874245
NCIH1694	DepMap CRISPR Gene Dependency	1.0	2.50236
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.7892
Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6015
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.77261
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2003
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	156.0
ZNF33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01079
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0655
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3152
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17244
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08851
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IC-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.4797
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.47222
Signaling by GPCR	Reactome Pathways 2014	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13021
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1676
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1458
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SNU620	DepMap CRISPR Gene Dependency	1.0	5.48907
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	107.906
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72907
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6166
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12248
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74936
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	187.667
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0824
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.28037
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.059
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.27435
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.860038
IRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17794
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-11A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	91.9413
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	2.03402
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1299
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0029
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08715
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3588
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19228
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56147
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40803
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01128
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
HEC116	DepMap CRISPR Gene Dependency	1.0	3.33583
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.6846
ZNF471	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49761
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.99227
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14261
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE185872_0_v_2_methotrexate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Auditory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.394
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.693656
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44895
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	1.33595
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.097
RL952	CCLE Cell Line Gene Expression Profiles	-1.0	-1.473
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47984
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64078
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856476
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	88.9389
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74307
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	86.4141
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3129
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9324
RERFLCAI	CCLE Cell Line Gene CNV Profiles	1.0	1.41832
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.39884
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22038
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07657
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.8171
MALME3M	CCLE Cell Line Gene Expression Profiles	1.0	1.37712
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.1327
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	2.81327
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6861
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839029
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00598
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4262
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	103.378
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9539
MTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45037
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5956
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49457
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2254
HT1197	DepMap CRISPR Gene Dependency	1.0	2.89688
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0036
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76304
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30701
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916952
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.255
TENT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07044
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
LAMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25895
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5263
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25967
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8735
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	184.066
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8329-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836188
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90893
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9231
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17473
breast	GTEx Tissue Gene Expression Profiles	1.0	0.893393
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216702,GSE216718_0_v_1_trex1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62084
sensory perception	GO Biological Process Annotations 2015	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83865
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.0435
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33614
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.317
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.400453
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.85721
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
Allergic contact dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5583
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54937
Atopic dermatitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1699
ZNF791	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77529
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24654
Contact dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931419
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6645
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMES1	DepMap CRISPR Gene Dependency	1.0	2.3016
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	218.248
Inner ear disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.394
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6236
MAFK	ENCODE Transcription Factor Targets	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17401
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE246983_1_v_0_cdk12_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1751
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16054
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.00767
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.73774
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4301
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FU-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC103H	DepMap CRISPR Gene Dependency	1.0	2.04757
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9415
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08715
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88028
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0605
H9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.429
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Y-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	147.294
SKRC31	DepMap CRISPR Gene Dependency	1.0	2.04345
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0188
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52464
CILK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.82461
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.355
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893282
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9478
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	17.2719
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82866
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.997944
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PRKAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64943
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89936
ESO51	DepMap CRISPR Gene Dependency	1.0	4.57771
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1577
496100544_PCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.70746
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11307
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4268
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900031
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.1404
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14288
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5317
Transcription export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.409
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836188
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82451
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9346
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LN443	CCLE Cell Line Gene CNV Profiles	1.0	1.35092
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95517
icSARS CoV_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.51465
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.40344
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.45312
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64791
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58671
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49457
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.9562
Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25967
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.2279
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10751
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.07506
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06923
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69729
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92209
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.8945
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89607
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30356
Lung adenocarcinoma_LUAD_TCGA-55-6983-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19199
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6003-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medium chain acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.36988
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	84.6964
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11423
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	108.73
Pork consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1372
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.84188
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51371
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.73746
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6436
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	72.7099
ARHGAP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2901
SNU1077	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83799
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.7297
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75412
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7405
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	86.395
KKU100	DepMap CRISPR Gene Dependency	1.0	2.20093
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61153
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7182
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836116
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.35092
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07274
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3214
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.293265
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.53021
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2658
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962717
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.5308
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37513
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53728
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.36311
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96251
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85513
EPHA4_knockout_227_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.31498
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6770-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	165.054
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8588
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90975
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	83.5616
NCIH838	DepMap CRISPR Gene Dependency	1.0	2.62511
BABAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23655
MIR221_KD_GDS4054_455_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2773
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00598
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6745
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39137
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.9213
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5449
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39614
integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.46288
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.7558
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44003
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925342
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1862
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.2193
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040595
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.394
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74698
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05182
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42932
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04558
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
SW1463	CCLE Cell Line Gene Expression Profiles	-1.0	-3.10955
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2205
CHLA57	DepMap CRISPR Gene Dependency	1.0	5.05824
PBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61513
interleukin-4 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF172	DepMap CRISPR Gene Dependency	1.0	2.13201
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2295
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.6267
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.342
Dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23083
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7487
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-358-ONECUT3_ONECUT3	Rummagene Transcription Factor Associations 2026	1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C32	CCLE Cell Line Gene Expression Profiles	1.0	1.36504
YD38	CCLE Cell Line Gene Expression Profiles	1.0	1.49496
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3882
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.0144
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6595
MOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44572
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5251
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	95.4438
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8438
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SISO	DepMap CRISPR Gene Dependency	1.0	2.53194
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4121
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89462
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0615
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Embryonic stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88158
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5025
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2127
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13213
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7912
GSE140714,GSE140716_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45426
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842422
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.04363
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19412
atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.865502
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.96473
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23616
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	89.6657
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55239
HCC2450	DepMap CRISPR Gene Dependency	1.0	2.33661
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1278
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4569
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8535
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	92.5458
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37547
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dermatitis, Atopic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.5812
biological regulation	GO Biological Process Annotations 2015	1.0	null
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83498
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.50951
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
External male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60148
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9773
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00598
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAN2	DepMap CRISPR Gene Dependency	1.0	2.62396
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	159.727
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928442
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29185
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-228-ZNF214_ZNF214	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0732
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7648
Kidney Chromophobe_KICH_TCGA-KN-8427-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6957
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8938
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1488
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.9014
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.897
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56558
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9704
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0587
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.6003
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-1.15709
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71152
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894837
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2612
KDM4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37813
Lung adenocarcinoma_LUAD_TCGA-69-7980-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VP229	DepMap CRISPR Gene Dependency	1.0	2.36207
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.9767
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.42869
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19347
KALS1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13798
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10081
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Atf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.8103
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.55799
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.70469
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12536
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7572
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.286
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
59M	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74152
SKMM2	DepMap CRISPR Gene Dependency	1.0	2.02114
PBX1	ChEA Transcription Factor Targets	1.0	null
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3626
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32838
Shrimp allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53031
MYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87699
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15653
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.11413
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
SLC39A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69703
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12114
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.59308
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.507
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	85.2485
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19199
PTGIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84222
EFO21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79317
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936143
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38861
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45462
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6453
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.6907
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35092
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83498
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
19192944-table2	GeneSigDB Published Gene Signatures	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-677-ENSG00000149050_ZNF214	Rummagene Transcription Factor Associations 2026	1.0	null
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4285
ERVMER34-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96823
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WI-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-6545-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
TP53_01_37	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59699
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61987
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9491
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37874
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	105.213
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	138.07
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VDR-20736230-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69858
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93697
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	76.8374
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.1493
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WA-07 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
RHJT	DepMap CRISPR Gene Dependency	1.0	2.74271
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
membrane	GO Cellular Component Annotations 2015	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1682
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.1674
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.925346
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9798
MC116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
atopic dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.46288
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9978
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80959
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3982
Acute Myeloid Leukemia_LAML_TCGA-AB-2854-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233183,GSE233187_2_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83498
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46034
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08851
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	143.588
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18732
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59009
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	3.13859
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.06
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955246
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67A-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A51X-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936143
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.14558
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79202
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.25887
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.5066
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AV-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51873
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12248
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9664
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Shellfish allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
HS839T	CCLE Cell Line Gene Expression Profiles	1.0	3.4059
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887012
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7627
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0547
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925264
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	123.299
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834165
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7789
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.523
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5003
H3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09588
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.328
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22685
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17397
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.970644
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02084
nfe2l2_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.17817
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G292CLONEA141B1	DepMap CRISPR Gene Dependency	1.0	3.26025
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92651
Perturb_4857_OE_KLF4_SRP194102	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.43027
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE168797_2_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27828
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7794
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.46288
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6333
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.84153
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.096
NB1643	DepMap CRISPR Gene Dependency	1.0	4.21798
SCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21811
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	82.3348
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52244
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3739
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32966
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7562
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69641
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7504
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0605
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6784
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2684
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12465
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LC4-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHLA266	DepMap CRISPR Gene Dependency	1.0	4.04621
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4636
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07215
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48226
CBFA2T3_KD_GDS4045_458_human_Non-Hodgkin's lymphoma Reh cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3452
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60296
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896378
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.4273
skin	GTEx Tissue Gene Expression Profiles	1.0	1.15608
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.387423
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1865
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.394
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peach allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60027
COLO792	CCLE Cell Line Gene Expression Profiles	1.0	1.64063
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	1.64399
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.650663
thyroid	GTEx Tissue Gene Expression Profiles	-1.0	-1.15709
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38843
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.5987
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4693
CAL62	DepMap CRISPR Gene Dependency	1.0	5.21543
dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.46288
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.4566
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8982
DPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55239
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	2.55527
Rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.988579
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87378
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36752
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory transduction	KEGG Pathways 2026	1.0	null
TNIK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12203
ELF1	ChEA Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
Prostate adenocarcinoma_PRAD_TCGA-HC-8259-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42522
NUDHL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45274
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5378-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9114
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HS-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.612
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	96.7275
ADCY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65374
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.486
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2544
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1727
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	129.693
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1025
mRNA_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8351
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7793
BACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79532
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-509-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1615
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8837
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5625
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8464
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36282
Prepuce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2235
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8185
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.9901
Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60164
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78441
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0515
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.60286
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.42138
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11423
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.71616
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.6854
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
MYC	ENCODE Transcription Factor Targets	1.0	null
TGBC18TKB	DepMap CRISPR Gene Dependency	1.0	2.14719
SNU398	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71882
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26518
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3429
Bladder Urothelial Carcinoma_BLCA_TCGA-LC-A66R-01A-41R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	103.338
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17928
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92651
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848768
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882194
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846497
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8499
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30763
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905428
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39075
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0008
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.43411
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14235
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.1259
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69499
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0013
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.3852
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4543
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	364.928
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5111
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841761
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16817
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936143
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.746
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17567
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915999
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19897
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963614
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49457
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0102
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	98.6751
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	115.662
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1844
Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.9994
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74393
EOL1	DepMap CRISPR Gene Dependency	1.0	4.08296
GLC82	CCLE Cell Line Gene CNV Profiles	1.0	1.36269
MOLM13	CCLE Cell Line Gene Expression Profiles	1.0	1.39183
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90888
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1614
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82367
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3857
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84846
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50022
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10241
CAVIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13457
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27512
Foreskin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71744
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.924327
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927096
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05182
Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18161
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26807
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29409
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	93.9977
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92651
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A627-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54859
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46821
PANC1	CCLE Cell Line Gene Expression Profiles	1.0	1.74008
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46694
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.841262
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63255
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Crustacean allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	111.915
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5U8-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.255
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30023
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.2851
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.7778
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1296
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73836
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842422
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	2.60647
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20645
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.12454
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855692
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.2034
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12248
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.8454
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847717
Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7012
CLDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50966
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08764
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.9543
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01556
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912061
Food allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.5312
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.1667
Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.85
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79397
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0288
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.8938
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48778
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60475
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48455
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.94256
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.8095
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	95.3469
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	88.7985
OV56	CCLE Cell Line Gene Expression Profiles	1.0	1.93802
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.47338
Sensorineural hearing loss	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.394
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14431
LU135	DepMap CRISPR Gene Dependency	1.0	2.09861
Sensory Perception	Reactome Pathways 2024	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BBX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43136
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5763
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.92132
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISTMES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05759
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DKMG	DepMap CRISPR Gene Dependency	1.0	3.24917
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.0984
Penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.233
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9846
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
DRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72037
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.1513
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-J1-A4AH-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIMA	DepMap CRISPR Gene Dependency	1.0	2.48826
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.0881
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4564
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.2598
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8262
CHSA8926	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.1511
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MM-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.7637
MRPL50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64013
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38843
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19255
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	145.813
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843899
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.78643
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89137
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.45312
ESS1	DepMap CRISPR Gene Dependency	1.0	3.69529
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20241
KDM5A	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C16orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00585
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-1.15709
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5231
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1072
TFPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56228
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20241
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gastrointestinal allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.3957
SGF29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3686
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2741
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50818
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5147
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6804
skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.46288
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05685
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05182
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FSCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83757
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6672
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89731
DNAAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88968
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.0833
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	2.02193
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.52797
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.4681
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37134
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.80147
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.46288
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
Allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17518
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76846
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SN-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00533
Perturb_12318_KD_NRDE2_SRP161520	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.42172
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9435
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87542
Kindler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
TE6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82767
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13462
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973773
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49629
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6689
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-WK-A8XZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185872_0_v_1_methotrexate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5862
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	2.98041
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
MYC	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896378
Lung squamous cell carcinoma_LUSC_TCGA-66-2783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1864
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925264
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	111.628
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846335
OCIMY7	DepMap CRISPR Gene Dependency	1.0	2.90558
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.8792
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2698
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846335
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75355
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58456
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.67139
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	88.9387
ICC4	DepMap CRISPR Gene Dependency	1.0	2.22857
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.83981
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6002
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.54968
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0405
S117	CCLE Cell Line Gene Expression Profiles	1.0	1.49711
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.951983
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35581
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75823
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41977
NCIH2172	DepMap CRISPR Gene Dependency	1.0	2.47157
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6769
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8222
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5215
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07426
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.574
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0525
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9316
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	218.017
HLFA	CCLE Cell Line Gene Expression Profiles	1.0	2.12099
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1907
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.8838
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92651
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.084
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9893
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846497
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15867
H3K27me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8588
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OMM25	DepMap CRISPR Gene Dependency	1.0	3.4701
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.533
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.838046
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10886
HEP3B217	CCLE Cell Line Gene CNV Profiles	1.0	1.33678
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.82437
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.394
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02518
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7369
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9924
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100499_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.95102
TMEM201	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67941
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9563
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5473
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81774
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28345
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35089
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178292_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	2.35233
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.1927
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97546
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7630-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	1.47461
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27345
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25888
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82477
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0884
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1692
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20384
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162015_1_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POMC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34934
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.27284
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50772
Atopic dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4148
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.052728
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6542
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34673
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834281
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87164
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7765
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.0728
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2578
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4102
Nut allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960543
EZH2	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44394
ZNF845	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96376
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980799
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	99.7825
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.41432
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08049
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1202
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS695T	CCLE Cell Line Gene Expression Profiles	1.0	1.87084
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4988
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4177-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.99227
RCOR1	ChEA Transcription Factor Targets	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9154
ST486	CCLE Cell Line Gene Expression Profiles	1.0	2.3129
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.7057
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XI-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5531
NRBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36633
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.56409
DLD1	CCLE Cell Line Gene CNV Profiles	1.0	1.37031
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20241
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HS766T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Npas4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6744
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33332
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99376
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62404
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.54943
ADPGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0636
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPARA_agonist activation_GSE17251_474_human_Isolated hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.806
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.61918
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.4626
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99414
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98693
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9477
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991439
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1365
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43285
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	2.15672
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039676
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32561
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.3302
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.8072
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82451
cell part	GO Cellular Component Annotations 2015	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	172.2
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.908
NCIH520	CCLE Cell Line Gene Expression Profiles	1.0	1.5642
786O	CCLE Cell Line Gene Expression Profiles	1.0	1.93792
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01632
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5684-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39556
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1399
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48509
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	99.4454
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.76
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.994477
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2012
MAFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05193
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69898
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05754
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4972
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.30613
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.1824
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0262
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2095
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.35627
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLR24	DepMap CRISPR Gene Dependency	1.0	3.48973
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1911
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.14271
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.7661
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N5-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.937
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.46479
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983804
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2235
IKBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96488
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A541-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39453
JHUEM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64537
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	3.03725
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
FGFR3_knockdown_174_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.81969
ATF1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7266
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35581
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1499
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.679261
COLGALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8327
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1975	DepMap CRISPR Gene Dependency	1.0	2.05348
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921519
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.79833
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3067
signal transduction	GO Biological Process Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73799
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53015
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69288
single-organism process	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38033
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92651
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.24447
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9204
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66443
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741