association dataset threshold value standardized value PRPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05201 Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GPRC5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82693 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5291 JHH6 CCLE Cell Line Gene CNV Profiles 1.0 1.92164 GPR62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22346 LTF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91972 FUOV1 CCLE Cell Line Gene CNV Profiles 1.0 2.02216 LIPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85294 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.960728 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2023 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100342_PCx_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.38805 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.2628 RPS6KA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.254 TUBB4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69499 H1-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17819 ALOX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85915 ZNF487 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65937 ESRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62265 bladder GTEx Tissue Gene Expression Profiles 1.0 1.0084 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32352 Sarcoma_SARC_TCGA-DX-A3U8-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.881247 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.106 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892315 CSGALNACT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25121 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20222 POU2F1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null MPZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65865 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02381 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988902 Prostate adenocarcinoma_PRAD_TCGA-J4-A67T-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.4927 Oily fish consumption GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 ADAM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24819 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.948179 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06033 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31245 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38354 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.966299 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3446 Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr11_7938026_A_G_b38 GTEx eQTL 2025 1.0 1.10175 External side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.848 CDC42EP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28326 SLC43A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77258 IHH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null TUBB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7536 plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 8.63156 outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37211 SZ in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03632 UROD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66679 CSTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47677 IFT140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60121 PLEKHG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35389 LRP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44991 STAT3 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68924 CEBPB ENCODE Transcription Factor Targets 1.0 null PRPF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28571 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.933167 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-677-ENSG00000149050_ZNF214 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.03936 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYDGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01638 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00395 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -2.00726 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.17762 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01394 PANC1 CCLE Cell Line Gene CNV Profiles 1.0 2.20362 membrane LOCATE Curated Protein Localization Annotations 1.0 null SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.4881 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3087 PGM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00267 KNS-42 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory receptor InterPro Predicted Protein Domain Annotations 1.0 null NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0086 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989742 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.48049 signal transduction GO Biological Process Annotations 2015 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-69-7980-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.827333 TRIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01051 PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925066 PIWIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84481 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1117 CBX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33491 Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.462 KLHL26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50175 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.347 Nasal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.018 HSCC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.479 dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.830419 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55476 MT-ATP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8797 Prostate adenocarcinoma_PRAD_TCGA-EJ-5495-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.874338 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875036 Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGFBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60842 NAALADL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47151 XYLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84754 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.995297 YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.64606 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.47934 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29802 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6366 ZNF669 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50924 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.977817 FOXN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86141 GSE171572_3_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54707 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.7972 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38649 detection of stimulus GO Biological Process Annotations 2015 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.2445 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09194 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28691 primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.00494 Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FUT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74353 EOGT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44711 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6777 RPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92319 TE1 CCLE Cell Line Gene CNV Profiles -1.0 -2.26621 Prostate adenocarcinoma_PRAD_TCGA-HC-7737-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRARP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5292 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19869 HS-68 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.349 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875036 IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5391 c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.06119 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46785 VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66834 JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19706 NH-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null JMY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57921 fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.888128 RNPEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.587 C19orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3997 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.22184 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Pork consumption GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 all GWASdb SNP-Phenotype Associations 1.0 0.028784 cd8.Tcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.869784 Foreskin fibroblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.085 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29716 Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.848 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4123 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 BGC823 CCLE Cell Line Gene CNV Profiles 1.0 1.35113 CCDC160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30343 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5776 RAB3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43274 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0702 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.937025 GSE205332_1_v_0_queuine_human RummaGEO Drug Perturbation Signatures 1.0 null LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5933 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.01105 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69066 rnf2_21051595_92dot1_lof_human_gpl10558_gse24896 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.661953 substance abuse GWASdb SNP-Disease Associations 1.0 0.344986 CYP2A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7242 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81552 CMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41909 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHLDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88702 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925066 IDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67982 BAIAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18498 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.58204 ZNF436 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14298 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.945339 DGKQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57589 Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPP2R5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48554 SDHAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57387 HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1613 bed nucleus of stria terminalis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.834518 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74624 RIPK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35865 MEOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80627 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90005 Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null salivary gland GTEx Tissue Gene Expression Profiles -1.0 -0.972765 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925066 Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FU-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CKAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06772 TRIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05181 GPCR downstream signaling Reactome Pathways 2014 1.0 null SORBS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87988 Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4479 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5489 PGBD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36273 ELOVL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02999 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31924 HOXC11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7365 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54714 496100341_TCx_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.56488 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.892336 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cornified envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.259 inner CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.963511 ZNF473 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64148 PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null SKMEL28 CCLE Cell Line Gene CNV Profiles 1.0 1.4146 NCIH1355 CCLE Cell Line Gene CNV Profiles -1.0 -2.14292 HCC2814 CCLE Cell Line Gene CNV Profiles 1.0 1.59355 Lung squamous cell carcinoma_LUSC_TCGA-56-5897-01A-11R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.30777 COV318 CCLE Cell Line Gene CNV Profiles -1.0 -1.49149 FH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09584 TLR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18674 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.6135 SLC27A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8402 SEPTIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69655 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5893 SLC35B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3541 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6995-01A-31R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00324 C1QBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92318 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64485 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16868 MFAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30664 MOTN1 CCLE Cell Line Gene CNV Profiles -1.0 -1.41461 H3K9me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.834713 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4685 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.834097 stratum pyramidale of rostral CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46428 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0832 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00324 POM121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20954 Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6353 inner SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.956352 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null CENPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17561 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853142 GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2025 1.0 null Perturb_4894_KD_ZBTB12_SRP158631 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.66344 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9365 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.33394 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intestinal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.529 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4188 496100559_FWM_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.46533 DUSP26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56904 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null ARHGEF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59209 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847321 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.786 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.26719 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23706 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Leading edge membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.266 g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null AAAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9856 CD37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77802 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHU-022 COSMIC Cell Line Gene Mutation Profiles 1.0 null ATF3 ENCODE Transcription Factor Targets 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925066 GTF2F1 ENCODE Transcription Factor Targets 1.0 null amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.7749 KYSE-520 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.94537 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.815 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MON2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74867 CSPG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05001 CCDC88B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52977 MPV17L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68554 MZT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74508 ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.830419 CEBPB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 NUCKS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.316 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7373 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55349 Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8889 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.8304 Cecum cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.635 JIMT1 CCLE Cell Line Gene CNV Profiles -1.0 -2.63569 DNAJB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21288 ATP11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41444 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82719 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.04218 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX3X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86359 GAPDHS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46245 HOXA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92764 MAP3K9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62736 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5195 Signaling by GPCR Reactome Pathways 2014 1.0 null DNAJC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20519 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13293 SNU-C1 COSMIC Cell Line Gene Mutation Profiles 1.0 null g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.4375 SSH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38294 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.78672 H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5641 NNT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48938 MYH9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30811 Allergic contact dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0854 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9634 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911091 GSE77108_8_v_1_saha_human RummaGEO Drug Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gastrointestinal endocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.019 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null RUVBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48033 Perturb_12225_KD_PRMT6_SRP131294 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.28645 PRORP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84699 H2AB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8037 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREB3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86677 alcohol dependence GWASdb SNP-Disease Associations 1.0 0.851323 DHX36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56982 Swim bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.572 MYB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42898 S100A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76555 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.896243 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980596 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30545 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.91648 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9936 TYSND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63663 ZNRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82246 TMEM92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7817 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.857526 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20266 GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null NEUROD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01735 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3464 TEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9951 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26202 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4881-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16933 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ZBTB40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42044 olfactory receptor activity GO Molecular Function Annotations 2023 1.0 null NHEK cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.354 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 NARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60528 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRA_01_115 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.74982 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.54085 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null molecular transducer activity GO Molecular Function Annotations 2015 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988902 BAZ2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16259 CPZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39658 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5384 GSE209698_0_v_1_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null Smoking initiation (ever regular vs never regular) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 PMC9727756-media-2.pdf-76-DMTF1_DMTF1 Rummagene Transcription Factor Associations 2026 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 1.0 5.90982 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2699 FSTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08894 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16404 substance-related disorder GWASdb SNP-Disease Associations 1.0 0.270024 orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00318 ZNF488 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80461 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.65 NDC80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18948 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.6245 DNMT3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80589 GLC82 CCLE Cell Line Gene CNV Profiles 1.0 1.3629 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5892 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.834713 DDT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04809 MDAMB453 CCLE Cell Line Gene CNV Profiles -1.0 -1.87389 35 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.144 PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.86342 Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.657 Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4742-01A-02R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0813 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.49034 HUG1N CCLE Cell Line Gene CNV Profiles -1.0 -2.87434 dorsolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44875 TBK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13388 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44875 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ARMCX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06714 RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5184 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24295 MAD2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.4586 FHL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18539 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O7-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IER3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24723 RT11284 CCLE Cell Line Gene CNV Profiles -1.0 -1.43597 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.313 SAP30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87156 CNFN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04028 Lung adenocarcinoma_LUAD_TCGA-55-6983-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS6KA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96038 AAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26333 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.906486 MEIOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52313 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.873156 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178340_1_v_3_carfilzomib_human RummaGEO Drug Perturbation Signatures 1.0 null DRAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63368 regulation of cellular process GO Biological Process Annotations 2015 1.0 null MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8605 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8505 HTR1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1147 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.973636 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67038 ZBTB45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17395 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.38923 FEZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52078 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16909 Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.985883 Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N5-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1954 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.10636 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3427 MGST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5133 NDUFA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26757 GJC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98627 GAS2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91852 MAP7D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88292 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.824027 HEP3B217 CCLE Cell Line Gene CNV Profiles 1.0 1.33696 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846115 PKP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46936 Lung adenocarcinoma_LUAD_TCGA-50-5941-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXD11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8337 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Contact dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.844512 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09667 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.864108 HSC3 CCLE Cell Line Gene CNV Profiles 1.0 1.36332 RAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17238 INTS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33066 membrane GO Cellular Component Annotations 2015 1.0 null LN443 CCLE Cell Line Gene CNV Profiles 1.0 1.35113 ATF7IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03589 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9576445-IJG2022-9264555.nxml--Potential_targets_of_hsa-miR-15b-5p_AND_hsa-miR-184_NOT_hsa-miR-16-5p_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.27501 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.68589 SLC1A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36409 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.859125 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0992 biological regulation GO Biological Process Annotations 2015 1.0 null HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.70414 GSE120216_3_v_0_cbfb_human RummaGEO Gene Perturbation Signatures -1.0 null NECAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60317 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.051 APUD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.021 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.25 RBM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84485 PMC10247733-41408_2023_863_MOESM2_ESM.pdf-358-ONECUT3_ONECUT3 Rummagene Transcription Factor Associations 2026 1.0 null stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.98927 H3K27me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAB3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89972 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62478 layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41121 osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.37559 ZNF844 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64766 JUN_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29913 embryoday7.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.981916 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.8052 BOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95923 JSC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90005 ADM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18578 PDE12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98161 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 496100583_PCx_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.75036 ATP5PF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46193 LYSMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07034 DCAF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47879 POLR1F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3381 SF268 CCLE Cell Line Gene CNV Profiles 1.0 1.78688 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH2286 CCLE Cell Line Gene CNV Profiles 1.0 1.3991 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26927 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36642 UWB1_289 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8146-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6971-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gas bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.567 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45018 EOLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04831 POR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73268 sensory perception of smell GO Biological Process Annotations 2025 1.0 null SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04461 UGT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07234 Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.98 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3315 HCC202 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.880299 GPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62564 TMEM86B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53277 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19727 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09623 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NKX2-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12046 INPP5F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93482 GBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53496 Sarcoma_SARC_TCGA-WK-A8XZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.977817 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68764 VPS39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98919 amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.845888 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.94537 Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0832 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54707 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null outer SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.928728 Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8616 HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.03682 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5710-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38347 TRIM45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33965 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28534 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45197 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5554 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHFPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12934 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19727 Olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.531 SP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07916 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5834 VAV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45258 A-431 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.928 Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2-25802403-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 BRCA1 ENCODE Transcription Factor Targets 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00324 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.016 Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.497 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74334 HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.678098 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null spleen GTEx Tissue Gene Expression Profiles -1.0 -0.972765 pyramidal cells of rostral CA4 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.8751 BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5928 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06033 RGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10075 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.60729 SRSF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9166 Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN7 CCLE Cell Line Gene CNV Profiles 1.0 2.7166 Expression and translocation of olfactory receptors Reactome Pathways 2024 1.0 null QKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83771 HDAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61598 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.261 primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21047 receptor activity GO Molecular Function Annotations 2015 1.0 null laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.962414 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6277 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 81.5786 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4557 FOS ENCODE Transcription Factor Targets 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null ARF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56127 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.14289 Respiratory mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.424 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158834_12_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1611 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.953327 POU2AF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09754 CALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51855 NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99932 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.918129 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Honey TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.073 PDE6D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85547 JUN ENCODE Transcription Factor Targets 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28893 RHOB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92174 Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX3-2 JASPAR Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory Signaling Pathway Reactome Pathways 2024 1.0 null PAQR9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50302 Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.087133 IZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.957069 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1352 PDHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41955 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.88788 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.581 GSE85880,GSE85881_4_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null FARP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43595 CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2082 MDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65925 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07164 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2023 1.0 null MESP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13206 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.4286 OR2B6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85325 HECTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84278 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.55151 ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.8022 BAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54388 FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27057 Prostate adenocarcinoma_PRAD_TCGA-XJ-A83H-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF491 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11643 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.80684 TGFBR3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85664 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.943526 DLD-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846115 TRMT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.93359 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48948 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.936453 posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38165 PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC Rummagene Transcription Factor Associations 2026 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67A-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.888791 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.12002 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925066 MRPL45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95001 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.832 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9619 RNF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7738 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83591 ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8177 PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.06078 OUMS-23 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS27 CCLE Cell Line Gene CNV Profiles 1.0 1.37011 ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2458 KCTD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50772 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.9714 RBL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47228 ACTMAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15255 ACSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47254 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38165 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19727 ZSWIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41537 integral component of membrane GO Cellular Component Annotations 2015 1.0 null Ruffle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.232 PNPLA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01115 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48948 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.07984 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22865 ventrolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15496 MEF2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71949 GSE205332_2_v_0_queuine_human RummaGEO Drug Perturbation Signatures 1.0 null CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7293 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GPR107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25223 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A89H-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8413 RARB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25133 plasma membrane GO Cellular Component Annotations 2015 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0832 RELCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2816 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null ABCA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42927 Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7630-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null cell part LOCATE Curated Protein Localization Annotations 1.0 null KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.44709 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE133763_0_v_1_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null IZUMO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20174 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39875 PANC0203 CCLE Cell Line Gene CNV Profiles 1.0 2.46505 GRHPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64351 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37741 PRDM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32539 JURLMK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.62305 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50648 BCAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27404 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45061 ATP1B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66956 ASPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53386 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28791 MAP4K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40374 SLC25A39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15243 TDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00016 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.973636 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15784 mammarygland.lact. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.840985 Brain - Hippocampus GTEx Tissue Gene Expression Profiles 2023 1.0 3.86673 ASNSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66937 RER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58459 PIK3C2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81232 Ruffle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.05 USP16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21003 DLD1 CCLE Cell Line Gene CNV Profiles 1.0 1.37053 STAT3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16524 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911545 CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0439 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.945129 Myopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 COLO-680N COSMIC Cell Line Gene Mutation Profiles 1.0 null ASB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80041 MGAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5328 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3579 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.60798 olfactory receptor activity GO Molecular Function Annotations 2025 1.0 null lateral hypothalamic area, tuberal part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.842557 Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PFKFB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43935 hippocampus (hippocampal formation)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.936453 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.847092 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26045 hippocampus (hippocampal formation)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06434 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7858 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1681-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LNCaP clone FGC TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.146 ZNF500 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88737 496100597_HIP_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.90433 FAM3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41126 NUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7888 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38165 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.47655 HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.79876 ARID3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95479 C2orf68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9282 Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48948 CFAP97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43278 Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WFDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54207 ATF1 ENCODE Transcription Factor Targets 1.0 null AKAP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93167 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSPA1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30301 TMEM254 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91999 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.830419 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47237 NCIH1703 CCLE Cell Line Gene CNV Profiles -1.0 -2.07166 Lung squamous cell carcinoma_LUSC_TCGA-J1-A4AH-01A-31R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0686 posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51594 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13293 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.51124 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FXR MotifMap Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6DY-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3C7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19464 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04155 Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH5 CCLE Cell Line Gene CNV Profiles 1.0 1.56454 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARHGEF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90776 Olfactory transduction KEGG Pathways 2026 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32093 NR1H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57946 HCC1806 CCLE Cell Line Gene CNV Profiles -1.0 -1.96369 BARX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06207 SH3PXD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2961 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.926652 ZNF101 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58361 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.6081 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05829 cell part GO Cellular Component Annotations 2015 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837072 JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1263 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Clove TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.567 Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21811 SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6038 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05159 GSE171572_0_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -0.972765 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22133 Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.046111 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39627 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Medium chain acyl-CoA dehydrogenase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 COX5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47355 ZNF839 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6601 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09505 NUDT22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46131 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05201 GSE106661,GSE106665_0_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CD164L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04168 SARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58551 Lung squamous cell carcinoma_LUSC_TCGA-56-8305-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PKP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85391 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.82535 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.702 detection of chemical stimulus GO Biological Process Annotations 2015 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837072 Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL-JUSO COSMIC Cell Line Gene Mutation Profiles 1.0 null SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03362 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08454 CST6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91073 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08454 dorsolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00848 FOSB::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9139 NFATC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10041 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82026 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37104 Sensory Perception Reactome Pathways 2024 1.0 null GALR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00574 CCRF-CEM COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.745419 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.10276 Lung adenocarcinoma_LUAD_TCGA-MP-A4T9-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14124 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24022 Dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 stratum oriens of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.873538 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05201 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51506 Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C4orf3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61582 anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15496 TRIM41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89181 CEP72 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05569 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028809 Bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.521 HOP-92 COSMIC Cell Line Gene Mutation Profiles 1.0 null ASMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44095 SMC1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88292 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIK3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67045 ZSCAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72208 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08904 TP63 ChEA Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-A5DI-01A-31R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05201 FZD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56835 Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHRDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24296 Olfactory Signaling Pathway Reactome Pathways 2014 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A627-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.831648 NEURL1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66833 HNRNPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45877 TEPSIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89934 MTMR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62397 ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15496 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP1R16B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00698 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.13139 TOB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3018 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13492 SJSA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52663 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALKBH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00212 PMC9860384-mmc2.xlsx-Table_S4-Table_S4_2016_VCF_Shared_Variants_related_to_the_results_TBX1 Rummagene Transcription Factor Associations 2026 1.0 null PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2179 Signal Transduction Reactome Pathways 2014 1.0 null JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF813 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42297 Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.86484 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.5882 STC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52319 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14313 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1584 GULP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25546 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.245 Smoking initiation GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.804576 BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4265 KIF3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65538 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.856103 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16524 orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.920574 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7502 Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null alcohol abuse GWASdb SNP-Disease Associations 1.0 0.851323 LUZP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61949 IFNAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30471 SKIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44809 membrane LOCATE Predicted Protein Localization Annotations 1.0 null TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1295 MRPL28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6369 AZI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3671 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.45343 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989742 NEURL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87683 NR5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.42502 BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9002 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12538 PSKH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55992 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38165 Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15496 CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.27524 SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.59616 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2015 1.0 null TPRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.804 inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.936453 cell part LOCATE Predicted Protein Localization Annotations 1.0 null POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2072 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.936453 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06033 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22603 G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null MBIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1744 VSX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32345 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925644 CHMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28634 Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.941 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83591 UMPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76695 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1427 RERFLCAI CCLE Cell Line Gene CNV Profiles 1.0 1.4186 THBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17429 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96903 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988902 primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.830419 SOX2 ChEA Transcription Factor Targets 1.0 null JUN_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UHMK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27615 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.900781 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.92 SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 1.45343 POLD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35854 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38354 SAMD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19323 anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.915139 H3K27me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.678 primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31924 CUL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23198 SOCS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00165 DHDDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83184 Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.98926 GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null TGM2_KD_GSE23702_715_human_NB4 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null signaling receptor activity GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr11_7967634_A_G_b38 GTEx eQTL 2025 1.0 1.09641 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.6454 GSE171837_0_v_3_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null Intestinal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.607 SNTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21893 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55492 PNMA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37753 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20801 ZNF664 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47219 CTCF-21964334-BJAB-B-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.7022 Pia mater TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.503 LKAAEAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52222 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.89408 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5106 SLC20A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23619 RFX5 ENCODE Transcription Factor Targets 1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.36122 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.934935 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.35362 PIP4K2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35204 CAND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89167 WHAMM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77615 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14211 GSE173394_1_v_0_nfatc2_human RummaGEO Gene Perturbation Signatures 1.0 null skin GTEx Tissue Gene Expression Profiles 1.0 1.47494 ACAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74478 ZBTB39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88537 SMARCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88841 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45263 IGF2R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73669 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2025 1.0 null FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3403 SYNGR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42307 NCIH1650 CCLE Cell Line Gene CNV Profiles -1.0 -1.67729 Bladder Urothelial Carcinoma_BLCA_TCGA-LC-A66R-01A-41R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCL11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15988 GSE158834_2_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.965 H2AFZ ENCODE Transcription Factor Targets 1.0 null TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HECTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94301 BEND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4728 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.903473 ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7131 EIF5AL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60724 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4378 FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8447 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4733 Atopic dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.593 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null ZNF318 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93801 PTAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5048 THEM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88385 RIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64541 PARK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83236 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.839806 Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4814-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.347 Skin fibroblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.992 Brain Lower Grade Glioma_LGG_TCGA-HW-8321-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ethmoid bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.555 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38525 ZNF460 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81345 response to stimulus GO Biological Process Annotations 2015 1.0 null ZNF131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10552 disease GWASdb SNP-Disease Associations 1.0 0.028772 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-228-ZNF214_ZNF214 Rummagene Transcription Factor Associations 2026 1.0 null H3-3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95405 CENPK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09777 H3K9me3_U2OS_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.920117 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.908 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5108 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15496 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 sensory perception of smell GO Biological Process Annotations 2023 1.0 null SLC8B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71178 ST14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59268 H3K27me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.88933 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6389 IRS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42324 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43024 NSMCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74991 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.919209 SNU761 CCLE Cell Line Gene CNV Profiles 1.0 1.33614 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36324 Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Enteroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.023 UBTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79492 Allergic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 ATF3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 5g3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.97 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05201 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875036 CP in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13485 DTX3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84199 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84748 MTMR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89212 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2393 PYCR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1783 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.4011 NCOA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4769 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.27901 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77852 CLDN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93902 SU-DHL-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04268 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.875179 ASPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10596 KCNJ14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37215 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886129 Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0523 RDH14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32214 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2819 RNF227 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92939 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07293 cellular_component GO Cellular Component Annotations 2015 1.0 null C2CD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10494 Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67512 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC1A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10554 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34846 PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null NCIH292 CCLE Cell Line Gene CNV Profiles 1.0 1.45692 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1819 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43588 VMRC-MELG COSMIC Cell Line Gene Mutation Profiles 1.0 null BON-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.755 Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7298-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9065 BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9100_KD_Tfpi_SRP312891 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.63949 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.39422 NCI-H716 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.00494 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49643 Lung adenocarcinoma_LUAD_TCGA-44-6776-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27305 Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 EIF4G1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91695 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QZ-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8412 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0421 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5533 Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.937 KP-N-RT-BM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null TMEM25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28275 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.915654 EP300 ENCODE Transcription Factor Targets 1.0 null MACO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24527 SLC30A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43313 RTN4RL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36192 transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Malaria GWAS Catalog SNP-Phenotype Associations 2025 1.0 6.83979 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.06534 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923839 ZNF433 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44264 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20222 Olfactory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.441 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923839 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5993 Cribriform plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.572 SNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0911 NR1D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08645 IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887957 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.862 NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7283 olfactory receptor activity GO Molecular Function Annotations 2015 1.0 null GSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38134 RMND5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71812 amygdaloid complex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.864108 spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.835088 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3436-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GMPPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74294 ZNF566 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48042 HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.06837 Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.31289 CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8635 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.9198 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5361 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALDH5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13697 HOXC9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0533 ARHGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55757 TSPAN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02196 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -0.972765 C15orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88678 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.53 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3888 ETNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33914 TMEM151A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26996 GSE193541_0_v_3_nifurtimox_human RummaGEO Drug Perturbation Signatures -1.0 null BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2959 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.6622 SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.949349 substance dependence GWASdb SNP-Disease Associations 1.0 0.270024 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81552 EP300_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ICAM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83792 ZNF827 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75965 membrane part GO Cellular Component Annotations 2015 1.0 null TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5287 ABHD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92412 LMNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25907 CAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51978 Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null signal transducer activity GO Molecular Function Annotations 2015 1.0 null LRRC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56517 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90005 RPH3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53027 NPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81711 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0003 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4598 ATP2B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55269 MOLM-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10434_KO_PPFIA1_SRP127326 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96593 CSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41016 NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.42159 COLO-741 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.81515 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.72893 TOP3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6302 TRIM13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57568 COBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7293 Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.910833 Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46339 NDUFB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48778 PEDS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65268 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HES1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12083 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.977817 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34579 JUND ENCODE Transcription Factor Targets 1.0 null IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.866782 GYPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32851 ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.872637 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56334 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.977817 anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00919 Pancreatic adenocarcinoma_PAAD_TCGA-RB-A7B8-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15177 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.89588 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.608 ATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1584 SCC-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.9267 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837685 AGPAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80033 amygdaloid complex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90005 Keratinocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.023