association	dataset	threshold value	standardized value
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7364
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.575986
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.575986
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Signaling by GPCR	Reactome Pathways 2014	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7803
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.87906
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.00529
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2789
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.989
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34296
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4128
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2777
PMC11625982-AJH-100-10-s001.pdf-71-ZNF709_ZNF709	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57368
Prostate-t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.986764
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7545
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7425
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
496100345_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47559
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0569
496100571_FWM_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17852
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1731
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7863
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.604
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.575986
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5294
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.10669
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8891
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61253
496100544_PCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42399
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8497
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9684
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6621
Sensory Perception	Reactome Pathways 2024	1.0	null
496100424_FWM_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22089
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.03019
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3448
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03147
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73315
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3462
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6449
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1743
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0962
Signal Transduction	Reactome Pathways 2014	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6179
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70006
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.38559
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2012
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9937
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.83882
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2386
496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08263
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4225
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5332
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02508
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01772
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	3.93173
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2491
Olfactory transduction	KEGG Pathways 2026	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.575986
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9811
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0954
496100526_TCx_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.61586
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5747
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.37002
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43154
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7827
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4871
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.82162
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0942
496100613_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.71373
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183327,GSE183328_3_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9225
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9071
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3409
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4312
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5613
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7408
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-AsPC1_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
496100550_TCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27032
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2439
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_AsPC1-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57869
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100533_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76291
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6646
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.575986
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1245
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1966
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4658
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9234
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3384
