association	dataset	threshold value	standardized value
BRD-K76640951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68957
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8052
BRD-K75007044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64524
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9841
receptor activity	GO Molecular Function Annotations 2015	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9511
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99849
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0266
Parasubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63582
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4417
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979322
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88213
Prestwick-692-2165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.82541
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41968
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39572
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K72125659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03939
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65807
BRD-K65166009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16557
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32458
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16317
Entorhinal area, medial part, dorsal zone, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45064
BRD-K66700691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87067
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.1449
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5896
Pancreatic adenocarcinoma_PAAD_TCGA-US-A774-01A-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
SF126	DepMap CRISPR Gene Dependency	1.0	2.37214
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.938683
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42328
BRD-K12411112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16136
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08574
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7355
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.51549
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01194
BRD-A68842442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89295
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN011_HEPG2_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09785
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21561
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2792
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934359
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7007
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18784
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
BRD-K40011635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81336
BRD-K07530355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76267
BRD-K05118964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27449
gramine-3999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluphenazine-3194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02190643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37642
BRD-K64770897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44455
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08916
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30684
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0067
BRD-K16355056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25198
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.88932
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84073439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35683
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.28099
FOSL1_KO_GSE43695_681_mouse_lung, bleomycin treated	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K26063034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34789
BRD-K12492021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35072
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66276
BRD-K26765362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32258
BRD-K31187110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14873
Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fenbufen-4743	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
prednicarbate-5544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83775
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1489
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88307
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986821
MORCPR	DepMap CRISPR Gene Dependency	1.0	2.17028
BRD-K62979806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36482
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12619
BRD-K01910220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1136
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K09819684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43196
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07495
PMC11554977-40199_2024_523_MOESM2_ESM.xlsx-Sheet1-Supplement_2_Metformin_Drug_Sensitivity_and_Damaging_Mutation_by_using_PRISM_Repurposing_Primary_Screen_and_Damaging_Mutation_in_DepMap_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87144
BRD-K01009153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78934
BRD-K40494117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28378
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17568
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52928
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K28029070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03769
BRD-K24191730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18626
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5153
HT-1376	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
BRD-K10284009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22805
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98107
Esophageal carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
hydrocortisone_homo sapiens_gpl201_gse21909	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65715
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.46622
BRD-K04834648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60459
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38279
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98364
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7522
BRD-K74811560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39707
tyloxapol-5672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
CRCGN016_MCF10A.TP53.M_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00137
BRD-K20053005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19893
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3918
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1303
BRD-K07981644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14421
DLD1	CCLE Cell Line Gene Expression Profiles	1.0	1.40082
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7866-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6101
streptozocin-6098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3958
CRCGN010_HEPG2_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05663
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927274
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8543
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07644
mantle zone of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25468
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
labetalol-3167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K46949676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16431
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9768
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02674
SARS-dORF6_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58719
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20649
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922552
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07802542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20922
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11607
tonzonium bromide-5678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47410882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46165
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47902
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7207
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.442
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09645
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.732158
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50043
CRCGN014_HEPG2_24H:M11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08276
LU65	DepMap CRISPR Gene Dependency	1.0	3.00473
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.14475
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1981
BRD-K46839342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37812
SOX11_DEPLETION_GDS4801_326_human_Z138 mantle cell lymphoma (MCL) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887987
BRD-K61039403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4756
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.40349
BRD-K92985620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08988
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K61486072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50645
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4459
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55064
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34389
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K43624274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23968
FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K67484361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80307
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
BRD-K15714104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78003
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866638
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30684
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8796
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88059
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05074
biological_process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ICC9	DepMap CRISPR Gene Dependency	1.0	2.75767
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954327
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21077
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84062787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90558
BRD-K91268803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28213
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1614
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941115
CRCGN014_HEPG2_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76096
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.75384
BRD-K59392325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55251
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9512
diclofenac-7215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	2.55086
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35199
KYSE-450	GDSC Cell Line Gene Expression Profiles	-1.0	-1.92535
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21325
BRD-K36084688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59695
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49757
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38655
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874093
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1637
BRD-K24133768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06277
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4407
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1134
BRD-K80724972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74456
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26951
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32993
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90389
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.72424
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6503
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5772
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.37232
cellular_component	GO Cellular Component Annotations 2015	1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1661
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02674
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.968452
CORL47	DepMap CRISPR Gene Dependency	1.0	2.01563
BRD-K58044926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01636
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5966
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02997
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K08835142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62426
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902105
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K75807882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03252
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01377
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44448
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25464
BRD-K23749313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42413
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45989
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13142
BRD-K02070226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28891
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24839
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30563
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25859
BRD-K40318276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6444
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7476
MS751	DepMap CRISPR Gene Dependency	1.0	2.20404
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Olfactory Perception	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.61109
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14178
NCI H226	BioGPS Cell Line Gene Expression Profiles	1.0	0.875024
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC15	DepMap CRISPR Gene Dependency	1.0	2.12991
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.58041
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.047
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.65843
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902945
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09883
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1258
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1052
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8496
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.36332
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.57868
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08301
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45298
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6586
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15817
sirolimus-6927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07357
HSC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91573
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11162
BRD-K19474742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14521
BRD-K37658621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48251
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.954893
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.98441
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14309706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38791
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21956
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.1514
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30857
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53937
BRD-K48113109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32691
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08473
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6905
NCI-H292	GDSC Cell Line Gene Expression Profiles	1.0	1.82316
BRD-K78866450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33863
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.334
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0948
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.12422
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.766
LS123	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64671
oxprenolol-5871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.98123
BRD-K61494613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20406
BRD-K28429328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6743
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07181
BRD-K28305165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51633
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18612
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13181
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0034
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61725
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9004
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
BRD-K52261313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4431
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3755
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVK18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91244
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81467
A_CA_04_2009_7dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.66112
SKUT1	CCLE Cell Line Gene Expression Profiles	1.0	1.54044
Adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
EBC1	DepMap CRISPR Gene Dependency	1.0	2.31355
BRD-K90702609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11615
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85229
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8804
BRD-K52152765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30283
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18469
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37055068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30118
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02875
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27826
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8911
Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10727
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1227
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10456
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53433
vagina	HPA Tissue Protein Expression Profiles	1.0	1.46622
breast	HPA Tissue Protein Expression Profiles	-1.0	-0.732158
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868491
Meningococcal infection_Umbilical vein_GSE4646	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48722
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15538
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08473
POLR2AphosphoS5_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.851902
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869013
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3988
BRD-K17420784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33107
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25464
BRD-K08311368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06601
Ishikawa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.037
Lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2349
BRD-K74363294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79677
BRD-K41603100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88447
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69806
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986019
NCIH358	DepMap CRISPR Gene Dependency	1.0	2.09111
novobiocin-2990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K00046588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45968
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31648
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TO175T	CCLE Cell Line Gene Expression Profiles	1.0	2.0753
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0091
BRD-K45612428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6868
BRD-K68364310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72274
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19096
BRD-K47593849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10207
BRD-K37872081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15729
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40573
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17188
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.79
BRD-K68985225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07205
Skin Cutaneous Melanoma_SKCM_TCGA-OD-A75X-06A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16317
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3821
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-A57285050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02604
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16047442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22858
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92424
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04283
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.54785
BRD-K64992851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04628
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45459
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5111
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8664
PTHrP_KD_GDS1664_438_human_MDA-MB-231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07358
BRD-K53814023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50945
BRD-K34501072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0139
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15395
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1694
Fra-1_KO_GDS5078_403_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84698
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
BRD-K41876347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59779
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2136
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2837
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02607
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0723
Signal Transduction	Reactome Pathways 2014	1.0	null
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44021
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42253
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58896
BRD-K12281552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43096
Uterine corpus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
mantle zone of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04047
BRD-K36393312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03484
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07932
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04497
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65719
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
BRD-K68618340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42495
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.94303
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82957
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93489
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07495
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	2.95203
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04349
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.514
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	2.84725
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2681
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6159
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOTO	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56337
NB69	GDSC Cell Line Gene Expression Profiles	1.0	1.50028
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3371
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24976
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976709
BRD-K05357297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7467
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53496
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15936
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	2.04823
PMC10290283-biol-2022-0622-sm3.pdf-492-FOXI2_FOXI2	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7177
BRD-K92655427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11476
WM-115	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53526
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5111
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20861
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.72148
HNMPA-(AM)3-583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19227
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14569
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21639
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2915
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69835
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66119
signal transduction	GO Biological Process Annotations 2015	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5926
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.30751
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95385525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35979
tanespimycin-221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27539
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09595
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5558-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.373
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3545
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.7221
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18283
BRD-K32506050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01734
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91814
BRD-K02329600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3639
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69649
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K58333451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66776
BRD-K34318928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67132
BRD-K04087396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2383
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.851731
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3647
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75884
BRD-K06174863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29478
testosterone-4676	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K37029442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02382
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59237
GSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88383
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
lateral terminal nucleus of the accessory optic tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49657
female preferences for male odors	GAD Gene-Disease Associations	1.0	null
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883152
BRD-K66039243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22213
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20433
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68928
lasalocid-3021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64684
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57357304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22691
BRD-K51787437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19062
BRD-K26161397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10793
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6037
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K51779559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04366
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6447
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.01375
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63582
D-502MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02045
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922552
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33913
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10947
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10117
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6542
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2957
PF-00539745-00-5974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2392
BRD-K01067435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1495
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61171
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3008
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08463
gibberellic acid-4234	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4734
BRD-K37047627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19036
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7984
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18346873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24983
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57861
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0675
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13142
GLI3T_Lipofectamine transfection_GDS4346_616_human_Panc-1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.66575
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9053
N-acetyl-L-leucine-5683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.79871
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4162-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10526
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17476
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16033
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65719
Esophagus adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18432
LN235	CCLE Cell Line Gene Expression Profiles	1.0	1.62964
BRD-K79355381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0326
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7712
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24188
HH	CCLE Cell Line Gene Expression Profiles	1.0	1.82891
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15807
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62747
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23295
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9544
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.897
BRD-K26257310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0544
Cutaneous lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
BRD-K41875112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25854
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.69952
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77221872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07812
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881707
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02736
BRD-K01669916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23877
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28828
BRD-K29469525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5262
BRD-K57778236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27517
SKMEL30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60366
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2498
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SKGI	DepMap CRISPR Gene Dependency	1.0	2.29991
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33399
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19171
BRD-K37033753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32974
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.015
GSK3B_knockdown_206_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.3322
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2755
CRCGN013_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20775
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81661
BRD-K56022813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09623
phenindione-5991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.868643
BRD-K74873856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33071
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.59207
ZR75_1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.75384
BRD-K05799189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13173
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.884721
alpha-ergocryptine-4374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60238606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44137
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881543
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06628
BRD-K23204014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16518
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
BRD-K25187028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13756
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47145
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90454
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09899
BRD-A80035237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13178
BRD-K51697562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24377
bromopride-4741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K80296876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22397
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58014
BRD-K20377072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27666
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28307
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10206
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45152
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62298
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60894
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55935
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06343
BRD-K32520360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74488
fenbufen-2308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59955
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2396
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.71983
CAS1	DepMap CRISPR Gene Dependency	1.0	2.20978
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45168
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
AML193	DepMap CRISPR Gene Dependency	1.0	2.45675
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941115
BRD-K69624346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80058
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
nipecotic acid-7296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
intermediate stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14828
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
HTK	CCLE Cell Line Gene Expression Profiles	-1.0	-2.41563
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70074
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.18305
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
altizide-2527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
Olfactory transduction	KEGG Pathways 2026	1.0	null
roxithromycin-4778	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11113
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99372
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8834
BRD-K45947503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29347
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51704
pioglitazone-5972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20303
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10117
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21728
BRD-K84693638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79364
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.8221
HEC1A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92756
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prestwick-857-3016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56988
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15001
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26196
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08301
BRD-K42976515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81524
BRD-K76755163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61469
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.05
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23177
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.93907
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08792
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07664
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0777
Brain Lower Grade Glioma_LGG_TCGA-DU-6542-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13275816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01712
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97826
BRD-K90625628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49363
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59382
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827217
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03868
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K67931592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32638
496100314_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2666
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Esophageal cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7579
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
RDES	DepMap CRISPR Gene Dependency	1.0	2.01457
BRD-K05950670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31975
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.44
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30519
CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCIH716	DepMap CRISPR Gene Dependency	1.0	2.86283
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3369
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09374
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
BRD-K34737616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33573
BRD-K56563145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12138
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03852
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3371
BRD-K78337983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42759
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1459
BRD-K90686530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64167
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0081
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.442
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.78
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7019
TE-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1341	CCLE Cell Line Gene Expression Profiles	1.0	1.46753
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K77316284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05622
BRD-K61934967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21467
BRD-K27888332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66448
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1092
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13461
BRD-K36064145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32789
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50915
MDAMB415	DepMap CRISPR Gene Dependency	1.0	2.32881
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17855
BRD-K82785545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17232
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5785
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5386
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3126
BRD-K37454185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44829
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8214
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89516
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07299
BRD-K11016405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9876
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989418
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.3388
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30208
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4779
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77872
BRD-A22502911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46342
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859143
BRD-K14375485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60465
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28828
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38464
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
BRD-K59045095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89369
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61431
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K27137352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54227
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00804
BRD-K72842159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77217
BRD-K82827604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91629
r4 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04047
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06323
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	1.0	1.37729
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40799
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9174176-41467_2022_30924_MOESM5_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0254
BRD-K09689420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38462
BRD-K46620987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11203
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4925
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
BRD-K54134201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23074
AdrenalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.944951
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0991
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01621
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	1.36555
BRD-K82681356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33084
SUPB15	CCLE Cell Line Gene Expression Profiles	1.0	1.98126
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03723
CRCGN015_MCF10A_48H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21758
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3674
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7129
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61171
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59065
superficial stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49551
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2116
KYSE150	CCLE Cell Line Gene CNV Profiles	1.0	2.00728
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43607
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23621
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K74896637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22557
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76581
PMC12003903-41531_2025_933_MOESM1_ESM.pdf-19-ZNF184_ZNF184	Rummagene Transcription Factor Associations 2026	1.0	null
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.51083
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	0.916325
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87487
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4404
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.26303
BRD-K54939987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32625
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.86052
BRD-K13090434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24184
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38508
BRD-K12708839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02108
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36786
benperidol-4781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1702
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2195
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04241
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89775
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46269666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05113
CRCGN015_MCF10A.WT.HP_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13445
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78939
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924923
BRD-K52657580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25442
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10216
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31648
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93325
Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20382
CRCGN013_HEPG2_24H:L24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03759
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58069
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K28184331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29276
P2URK562	DepMap CRISPR Gene Dependency	1.0	2.37324
BRD-K76980944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08453
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.32366
BRD-K53379620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01523
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41311678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.348
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82353
monorden-449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SHP77	CCLE Cell Line Gene Expression Profiles	1.0	2.5419
Fish- and plant-related diet	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21476
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4142
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48822
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05547
BRD-K74537058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34406
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.47052
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12957
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40165
BRD-K05616059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63701
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50475
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45657
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1573
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56139
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62487
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.30565
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3395
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89189
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11368
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61646
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-2.02319
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86847
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.98164
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23496
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03263
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41547
BRD-K43261169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1705
hexestrol-6077	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HS616T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.45876
BRD-K33787033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10351
BRD-K60758969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16722
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2285
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898994
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13004
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8516
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.981439
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26957
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13373
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57285
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8705
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80059
BRD-K03935681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97161
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985046
BRD-K11610091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20582
CRCGN014_HEPG2_3H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27427
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6884
pentetic acid-3049	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.01375
ICC12	DepMap CRISPR Gene Dependency	1.0	2.90681
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.03493
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.302
SW48	DepMap CRISPR Gene Dependency	1.0	2.6112
BRD-K16891407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05638
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93868
paromomycin-4420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869013
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13883
BRD-K87929769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05461
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31473
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46802
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1209
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02476
Umbilical cord blood cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.99797
EGR4_01_132	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.08298
naftopidil-4193	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02987495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64596
BRD-K05509844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63195
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06466
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18169
CREB1_01_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.26279
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08301
BRD-K61807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24171
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45775
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0565
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875098
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10117
BRD-K30594227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11328
BRD-K09583061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63799
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8314
tomelukast-222	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93187
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61065
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4497
BRD-K84052780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23318
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1958
BRD-K29138092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88792
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1852
KMBC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96213
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902945
Signaling by GPCR	Reactome Pathways 2014	1.0	null
BRD-K87080934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10728
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889458
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3187
VCAP	DepMap CRISPR Gene Dependency	1.0	2.07119
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7417
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4322
BRD-K07276273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26644
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5116-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58386
SK-MEL-24	GDSC Cell Line Gene Expression Profiles	1.0	1.58946
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2256
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35015
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1002
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924923
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K18101782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3886
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.05504
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.732158
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55912
BRD-K69087429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06645
BRD-K79067166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20038
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4448
BRD-K59865704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25103
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20965
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.169
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.533
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14269
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11024
BRD-K11672894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34439
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869013
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26604
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1656
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.990853
BRD-K60337438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75804
BRD-K96637326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35737
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23069
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36988
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q1-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56106
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53496
BRD-K01297681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75136
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31585
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21077
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20326
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09468701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98598
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72611
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11544
BRD-K87259147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32577
BRD-K75869095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57566
BRD-K03937692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50265
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78612514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3213
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2416
BRD-K01787291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40618
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8058
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4643
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08037
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.24327
BRD-K29183384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72338
BRD-K86584551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23766
BRD-K98444789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04367
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.2962
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
BRD-K54478142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21337
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08544
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5354
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85365
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K54042694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19141
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22154
Barrett's esophagus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.169
nabumetone-5428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Entorhinal area, medial part, dorsal zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41918
BRD-K17904341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53892
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19227646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2571
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0568
BRD-K25236390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7181
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97806
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07959057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40673
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25881
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10123
2,6-dimethylpiperidine-4543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K85912419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08497
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88059
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16238
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62146
JJN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K91575768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46776
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.91586
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32355
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66406
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3031
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02997
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38476
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02
BRD-K73692505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26194
BRD-K09919985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88725
PMC3464266__F3	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K61335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42861
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07221
BRD-K57115335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29921
skin	HPA Tissue Protein Expression Profiles	1.0	1.46622
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.90055
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21908
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45928581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24327
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67244
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03516
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80917
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44598
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4321
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.24655
BRD-K58762810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2125
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42873980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85984
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.905
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.66008
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25137
RUNX2	ChEA Transcription Factor Targets	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03575
Brain Lower Grade Glioma_LGG_TCGA-FG-8186-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20982
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31656
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.36806
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934359
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HJ-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04497
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K92144896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38537
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869013
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3031
BRD-K86077185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68362
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-1.01375
BRD-K45969405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39126
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1478
BRD-K97962579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40983
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26211
BRD-K09842906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26578
cell part	GO Cellular Component Annotations 2015	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4007
RI1	DepMap CRISPR Gene Dependency	1.0	2.6838
BRD-K22380421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22659
BRD-K02230174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69103
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16759
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2194
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5271
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2195
BRD-K86237035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10963
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.157
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999655
BRD-K98264372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5112
BRD-K64742599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2241
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0081
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11162
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3521
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66458
Bipolar Disorder_frontal cortex_GSE5389	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68669
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88059
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2458
BRD-K38111331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6507
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.14789
AU565	CCLE Cell Line Gene Expression Profiles	1.0	1.53589
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4158
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13531
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.74389
BRD-K11188962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30982
BRD-K76350099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05826
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K20415826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05282
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34974
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07221
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
BRD-K97943226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18328
BRD-K37724316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57956
2-iodomelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93572
GSE211744_2_v_0_gdf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9301
Esophageal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.169
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.01375
SKHEP1	DepMap CRISPR Gene Dependency	1.0	3.1014
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45493
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36996
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09733
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.442
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00037
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42067
BRD-K54837058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41257
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23932
BRD-K89232006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19664
BRD-K78866630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30339
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.22461
BRD-K15930345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03944
BRD-K92794990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.047
acetylsalicylic acid-5564	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39534157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55061
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8798
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2602
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES2	CCLE Cell Line Gene Expression Profiles	1.0	1.67731
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05344
Parkin_OE_GDS4476_55_human_U87MG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4101-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04283
LS-513	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59577
BRD-K18094884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62218
BRD-K98301999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28949
BRD-K34018387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76949
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04497
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5746
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05408
ATF2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JV-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89805341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23382
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8658
SW620	DepMap CRISPR Gene Dependency	1.0	2.32887
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35068
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.3723
BRD-K23064726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61121
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9232
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71841
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.02319
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
BRD-K55835264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45054
meglumine-6685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
diclofenac_oncorhynchus mykiss_gpl10704_gse23053	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K07496812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36105
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52185
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	1.0	1.46622
HGC27	DepMap CRISPR Gene Dependency	1.0	2.29184
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09979
BRD-K92399035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0042
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25769
BRD-K32491833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21115
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30684
BRD-K75453159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1831
BRD-K68223954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20266
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77733130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05967
BRD-K88156935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5858
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5993
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18978449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19419
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82035
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52649
BRD-K95860374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19299
CRCGN015_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4708
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K69854611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38532
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75685
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56428170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06499
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3483
BRD-K09903493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33227
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.6754
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.07048
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56139
Uterine corpus endometrial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
placenta	HPA Tissue Protein Expression Profiles	-1.0	-0.990853
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40087
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8971
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06947
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08858
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56395
methyl-salicylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66804
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.829
KYSE450	DepMap CRISPR Gene Dependency	1.0	2.4587
BL-41	GDSC Cell Line Gene Expression Profiles	1.0	1.96195
BRD-K60759770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22721
BRD-K93176491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06547
BRD-K27323347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26561
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3324
BRD-K13567350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32752
first (dorsal) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25811
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64113
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9898
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
GSE220520_3_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88059
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6271
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.42065
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06343
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48757
BRD-K11247495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88221
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09866
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7707
BRD-K15975627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30258
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21213
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83095019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38272
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49827
SARS-CoV MA15_Day4_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77066
BRD-K97733472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37993
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1059
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01125
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8082
BRD-K08715132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27305
BRD-K41993678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10259
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-358-ONECUT3_ONECUT3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-198-ZNF250_ZNF250	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12162
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.19717
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46919
BRD-K64904523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56594
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36847
MJ	CCLE Cell Line Gene Expression Profiles	1.0	1.44189
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06209
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69543
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850343
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01828
BRD-K45508763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07825
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.6322
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38289
BRD-K75038114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06914
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41679
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K18142082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43626
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3064
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5693
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25559116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17087
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.906
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	2.60401
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45064
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9351
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29498
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12399
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09428
IZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995341
BRD-K34980742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09589
BRD-K32965188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30661
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4655
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11189
BRD-K76713298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80647
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.940553
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89388
BRD-K37000177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14877
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28275
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04809
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08914
TC71	CCLE Cell Line Gene Expression Profiles	1.0	1.53212
BRD-K63864310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62043
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60239
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01214
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0029
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44203030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0891
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.859
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0095
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5187
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63656
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97342
BRD-K41538715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27839
BRD-K98793503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68154
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869013
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857035
BRD-K20906316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01657
BRD-K62318087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07215
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62742
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9468
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.6637
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46161
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36679
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23342
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02778
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
diflorasone-4158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0316
BRD-K43298189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26339
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62620616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07478
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3393
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00494
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6104
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33304
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K41433616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53819
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59511
BRD-K24178822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07276
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10368
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K20454972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18514
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51663
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.54145
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8934
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69481
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23064
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54396
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
BRD-K66577743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00312
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.442
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5617
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	1.51552
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88355
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12891
BRD-K80575072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21776
BRD-K09149805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30416
Entorhinal area, medial part, dorsal zone, layer 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39601
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69649
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860745
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32862
BRD-K49424866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55901
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6587
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4009
ECGI10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54791
BRD-K74198088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07437
BRD-K35222206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18135
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	1.02833
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7082
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37865854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4703
IOSE80	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01214
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68345
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02334
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4027
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.4927
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3121
BRD-K44062658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01804
PF382	DepMap CRISPR Gene Dependency	1.0	2.54968
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99456
BRD-K15202679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06436
BRD-K14823121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04023
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831907
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08376
FTC238	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28924
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.56961
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01618
BRD-K52232548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43571
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49232
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2801
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14793
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8197
GSE220520_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88355
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.72712
BRD-K25176380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13742
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07853
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.33973
mephentermine-4707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49745983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12501
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.547
BRD-K35122752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09461
BRD-K33597325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46284
BRD-K26399271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16278
BRD-K92891227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00969
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45908
BRD-K72602058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34957
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8951
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.195
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19444
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13745
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50822
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3226
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6627
BRD-K12665145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29331
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.39749
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36436
BRD-K98117883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25298
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2915
BRD-K16800391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33005
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39601
BRD-K95218317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03204
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09903
BRD-K10580455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00076
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12866
Brain Lower Grade Glioma_LGG_TCGA-F6-A8O3-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUT78	CCLE Cell Line Gene Expression Profiles	1.0	1.70812
BRD-K28512751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18865
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72995
NUGC3	CCLE Cell Line Gene Expression Profiles	1.0	1.47036
BRD-K31721388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90268
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0846
BRD-K28349636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10773
Retrohippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35199
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5219
BRD-K74116035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67756
dehydrocholic acid-5681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30857
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
epivincamine-6838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927657
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5621
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30653
BRD-K87277021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71376
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69445
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0387
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15198
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43555
BRD-K99116119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56168
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.442
monorden-2679	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12702054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05146
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31648
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5988
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07316
HEPG2	DepMap CRISPR Gene Dependency	1.0	2.06499
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32449
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
paclitaxel_rattus norvegicus_gpl890_gse5337	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58832
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862329
KPL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62301
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2	ChEA Transcription Factor Targets	1.0	null
SW620	CCLE Cell Line Gene Expression Profiles	1.0	2.43805
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.46622
BRD-K38493972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18901
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00179
pyrantel-5088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
U-2-OS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64924
BRD-K61438422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82927
BRD-K65054381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07243
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93554
BRD-K53489056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30828
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57591
BRD-K44858727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44622
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63023
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.63592
BRD-K66179451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15899
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04497
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62388
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3823
BRD-K36952018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06755
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04626
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57288
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.52738
Glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30123
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97094
INA6	DepMap CRISPR Gene Dependency	1.0	3.63064
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eldeline-3750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04409515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25287
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4623
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.45018
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25464
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1118
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17521
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3294
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14702
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1969
BRD-K32853527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56477
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23559
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02926
BRD-K14250524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69208
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10536
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4035
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6699
BRD-K99690279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18558
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
Field CA1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13962
BRD-K30551445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39632
PMC12003903-41531_2025_933_MOESM1_ESM.pdf-19-ENSG00000096654_ZNF184	Rummagene Transcription Factor Associations 2026	1.0	null
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09979
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30857
BRD-K61053165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37764
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70286
BRD-K05057860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04771
BRD-K28268716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52153
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.65646
scopolamine N-oxide-5436	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1393
BRD-K36627718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23017
BRD-K93990956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.154
BRD-K96615474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24086
dosulepin-5986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59311
BRD-K57173429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01235
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.8242
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1215
NCIH322	CCLE Cell Line Gene Expression Profiles	1.0	2.07812
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1176
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11805
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13142
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74566
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09428
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.54609
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57053
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36433
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K21125528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34572
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11377
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ATF2_S_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6667-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78898
CRCGN014_HEPG2_24H:F08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15081
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3315
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1628
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06308
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0587
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25321
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.406
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23496
BRD-K24727463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86252
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23764
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85292767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62312
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32049
BRD-K20368781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1877
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7148
PMC3464266__F3	PFOCR Pathway Figure Associations 2023	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4308
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.98299
SNB75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09605
SNU1079	DepMap CRISPR Gene Dependency	1.0	3.20019
BRD-K08212599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11874
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38952
BRD-K74677971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95505
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4556
BRD-K27028848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14837
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03032
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03263
PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07357
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51600962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04949
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25468
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60909
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898002
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77792
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934359
Asthma and major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4107
BRD-K99331577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36892
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48324
BRD-K44643967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86109
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8592
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94214
Carbohydrate metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.09214
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94163
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2634
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957815
Jacobsen Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17045
IGR1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56734
TYKNU	CCLE Cell Line Gene Expression Profiles	1.0	1.59269
BRD-K97263385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12489
BRD-K99302735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52634
BRD-K65196043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08806
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39563
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.442
BRD-K86722849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71097
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23342
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33223
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10117
Sensory Perception	Reactome Pathways 2024	1.0	null
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50307
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00606
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54431
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
BRD-K73678117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02114
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967031
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K05462252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19755
GSE217982,GSE217983_2_v_3_hgfac_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985046
LS-411N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61862
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00713
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45047
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.877
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.92485
SKGT2	DepMap CRISPR Gene Dependency	1.0	2.17287
BRD-K55896279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19353
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37542
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
COLO-320-HSR	GDSC Cell Line Gene Expression Profiles	1.0	1.53947
Field CA1, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13373
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8889
BRD-K22670776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90817
BRD-K78196882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12551
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51156
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1668
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10117
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46314
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62873
SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58882
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7216
CRCGN008_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13025
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K39223744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23628
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9169
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16838
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	0.969923
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985046
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02092
BRD-K80945184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02145
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22154
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893967
PANC-08-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A2780	DepMap CRISPR Gene Dependency	1.0	2.21689
BRD-K39664334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17252
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29708
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26804
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08631
BRD-K36021765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10377
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26859
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985046
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41964
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A68123879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27895
BRD-K37271110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0756
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63101
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5456
BRD-K72770355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1685
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36271521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80365
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3258
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K69872823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30865
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.18788
OC-314	GDSC Cell Line Gene Expression Profiles	-1.0	-1.92805
BRD-K82927098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89717
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4316
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38205
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02854
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51744
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18427
BRD-K71005143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63745
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2532
Field CA1, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09979
BRD-K94862255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25084
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6296
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10206
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837507
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K37479727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54823
Subceruleus nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31847
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01214
nicotine_myzus persicae_gpl9470_gse18658	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9575
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75532
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25668
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957938
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29846
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.33142
propidium iodide-2541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1135