association dataset threshold value standardized value ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13229 GSE119978,GSE180930_0_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Fra-1_KO_GDS5078_402_mouse_Lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63 Rummagene Transcription Factor Associations 2026 1.0 null K562 BioGPS Cell Line Gene Expression Profiles 1.0 2.41625 laudanosine-1741 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DU145 CCLE Cell Line Gene Expression Profiles -1.0 -1.65345 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K87889654 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.34319 macelignan LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01147 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.93587 BRD-K71251432 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59469 CRCGN014_HEPG2_24H:D03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.02567 PIMREG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78559 BRD-K80424876 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.25979 GSE140997_4_v_7_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null BRD-K63779242 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53866 TERF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59294 ventrolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29045 HES7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.78 GSE140997_4_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.968313 CRCGN011_HEPG2_24H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.94385 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.8156 SKM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.87195 BRD-K31672963 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05513 BRD-K16304302 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.73707 BRD-K04969760 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.90243 TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K71941064 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24532 BRD-K45732260 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33863 BRD-K69922285 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67749 ADSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29625 A172 BioGPS Cell Line Gene Expression Profiles -1.0 -1.08378 BRD-K44103530 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0429 BRD-K01478290 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20811 Uroepithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.171 CRCGN015_MCF10A_48H:J06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.08276 BRD-K46560430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22889 HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01761 CRCGN012_HEPG2_24H:G13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.65385 HCC1187 CCLE Cell Line Gene Expression Profiles -1.0 -2.53854 GSE225869_2_v_0_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null SNU668 CCLE Cell Line Gene CNV Profiles 1.0 1.80834 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20502 CRCGN015_MCF10A.WT.HP_24H:G06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.46215 etiocholanolone-3742 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.737746 BRD-K82791632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51801 BRD-K33951208 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87264 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03334 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870802 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851623 BRD-K49681465 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20984 CGTHW1 CCLE Cell Line Gene CNV Profiles 1.0 3.27866 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30331 BRD-K63579322 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22692 BRD-K83115645 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01515 BRD-K26184956 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05849 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85477 Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K25539387 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15833 KMS27 CCLE Cell Line Gene CNV Profiles 1.0 1.34792 OVMANA CCLE Cell Line Gene Expression Profiles 1.0 1.85026 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K49042040 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00697 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49G-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null ITK_defectivemutant_125_GSE28200 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.64812 NCIH727 CCLE Cell Line Gene CNV Profiles 1.0 1.64318 BRD-K83272071 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02104 PANC0327 CCLE Cell Line Gene CNV Profiles 1.0 1.48972 cellular_component GO Cellular Component Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82526 temporal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.91673 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.32109 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19909 BRD-K20253608 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32032 LEFTY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49751 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4899 NB13 GDSC Cell Line Gene Expression Profiles -1.0 -1.54219 BRD-K00263786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80377 RASA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81222 CRCGN013_HEPG2_24H:G02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.56513 BCAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27404 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46369 Bladder wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.999 BRD-K26163290 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47914 PK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52123 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.09769 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975841 BRD-K94277689 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43486 BRD-K69080049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.49807 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41696 BRD-K73355908 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01985 U251 GDSC Cell Line Gene Expression Profiles -1.0 -1.43355 BRD-K63813316 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04114 ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.898 CRCGN016_MCF10A.TP53.M_24H:O20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.19847 BRD-K57620855 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32468 Lung squamous cell carcinoma_LUSC_TCGA-85-8666-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F1 ChEA Transcription Factor Targets 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59233 BRD-K13146924 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58668 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1851 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN009_HEPG2_24H:F20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.9565 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K82562625 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24578 FOXQ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87314 CRCGN015_MCF10A.TP53.M_24H:M08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8202 CRCGN017_MCF10A.WT.HP_24H:P06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.28985 BRD-K25773863 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84055 CRCGN015_MCF10A.TP53.M_24H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.0247 Lung squamous cell carcinoma_LUSC_TCGA-85-8048-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NDUFS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37688 Anal canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.53 ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.36774 LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.791748 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.61911 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K64665523 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87515 BRD-K45044525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57542 precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11161 CRCGN016_MCF10A.TP53.M_24H:H08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.86985 regulation of cellular process GO Biological Process Annotations 2015 1.0 null BRD-K82774801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12173 Olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.421 BRD-K39179354 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05166 HARA DepMap CRISPR Gene Dependency 1.0 3.39121 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06006 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K85362541 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.14658 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03584 MEG01 CCLE Cell Line Gene CNV Profiles 1.0 1.34335 scopoletin-3131 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN014_HEPG2_24H:D01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.00154 Lung squamous cell carcinoma_LUSC_TCGA-22-0944-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2347 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2777-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C75 DepMap CRISPR Gene Dependency 1.0 3.49787 BRD-K34640380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17867 IRF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30023 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4636-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K42966513 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27994 BRD-K89121101 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37929 outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.890704 iohexol-5704 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K76154866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31416 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.90158 BRD-K07438795 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35192 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5647 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.835649 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 BRD-A55574211 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31117 BRD-K19225848 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.9535 BRD-K30361950 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01508 Retinitis pigmentosa 11 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.372 CRCGN016_MCF10A.WT.HP_24H:A22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.32582 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.0183 Lung adenocarcinoma_LUAD_TCGA-44-7662-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K30071505 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23881 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33727 MERO25 DepMap CRISPR Gene Dependency 1.0 5.50372 sirolimus-5602 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48432 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K85554193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51327 Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4878 Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K18494310 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28124 SLC7A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02931 BRD-K67042874 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05093 blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.933991 NCI-H2009 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.188 Urinary bladder cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.582 embryoday7.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.14619 CRCGN015_MCF10A.WT.HP_24H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.92546 BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9847 Epitheloid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.532 adrenosterone-3107 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00318 KYSE410 DepMap CRISPR Gene Dependency 1.0 2.7032 lobeline-1770 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SNU1196 DepMap CRISPR Gene Dependency 1.0 5.55664 BRD-K73430970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20057 Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN013_HEPG2_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.0514 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45793 EEF1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47438 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10719 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.536 Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-M39894156 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04717 HGC27 CCLE Cell Line Gene CNV Profiles 1.0 1.49734 Respiratory smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.13 TGIF2LY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75684 BRD-K56106571 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03645 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.70519 SW780 CCLE Cell Line Gene CNV Profiles -1.0 -1.57706 imatinib_homo sapiens_gpl96_gds3042 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K51490301 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52702 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.29285 prostate GTEx Tissue Gene Expression Profiles 1.0 1.16732 orbital frontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35661 BRD-K68162101 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2171 nadolol-4021 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE182680,GSE182683_5_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.17889 regulation of biological process GO Biological Process Annotations 2015 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1428 CCLE Cell Line Gene CNV Profiles -1.0 -1.50377 GCT COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K67096761 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75617 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04331 BRD-K37625653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19143 A4FUK CCLE Cell Line Gene CNV Profiles -1.0 -1.43149 NCIH322 CCLE Cell Line Gene Expression Profiles 1.0 1.94137 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38632 BRD-K13271778 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36652 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1194 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 D341Med DepMap CRISPR Gene Dependency 1.0 3.44477 YWHAE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79824 FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 103.648 Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A47Z-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.584 DECR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39099 myosmine-2199 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K66838288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03495 OVCAR3 BioGPS Cell Line Gene Expression Profiles 1.0 0.955165 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.63782 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.82451 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K63436783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44774 COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 NCIH82 DepMap CRISPR Gene Dependency 1.0 2.64302 BRD-K83189379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.07837 BRD-K40057256 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07288 C3A CCLE Cell Line Gene Expression Profiles 1.0 1.49491 Kidney Chromophobe_KICH_TCGA-KM-8441-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30306 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.26883 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.871269 MOLM13 DepMap CRISPR Gene Dependency 1.0 3.75037 BRD-K69505608 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25837 NCO2 DepMap CRISPR Gene Dependency 1.0 4.48409 BRD-K36134264 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69237 orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.932347 SOCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13741 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1792 DepMap CRISPR Gene Dependency 1.0 3.4011 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K67082570 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25774 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.106 CRCGN016_MCF10A.WT.HP_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.05177 HEK 293 T-rex BioGPS Cell Line Gene Expression Profiles 1.0 1.53844 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB468 DepMap CRISPR Gene Dependency 1.0 2.44537 BRD-K60531990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00079 BRD-K80819226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6059 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06186 fulvestrant-367 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null azacyclonol-2020 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12536 Lung squamous cell carcinoma_LUSC_TCGA-22-4609-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K31602464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20529 septal organ BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 BRD-K06537903 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29104 Nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.453 Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K44946060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20579 KELLY CCLE Cell Line Gene Expression Profiles 1.0 1.37808 Prostate adenocarcinoma_PRAD_TCGA-G9-6499-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT483 CCLE Cell Line Gene CNV Profiles -1.0 -1.56459 nrf1_22586274_liver_lof_mouse_gpl4134_gse35124 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.043506 BRD-K50053371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59014 BRD-K69960043 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51582 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.952534 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82899 PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN017_MCF10A.WT.HP_24H:O14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.297 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2023 1.0 null INO80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02775 orbital frontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.919119 BRD-K16554464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11882 membrane LOCATE Predicted Protein Localization Annotations 1.0 null GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1513 fludroxycortide-2184 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K97595801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25631 BRD-K39029679 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10669 chrysophanic-acid LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.183 MYC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23895 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35673 BRD-K02637547 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.05383 FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3935 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851623 BRD-A69786436 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23623 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30726 BRD-K66973998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43596 LIVF001-009 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71916 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16619 Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.974203 dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null olfactory receptor activity GO Molecular Function Annotations 2015 1.0 null RALDH2_KO_GSE43578_6_mouse_head (rostral or posterior) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K95428783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33048 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03022 BRD-K97537859 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89922 BRD-K23553911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10722 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3Z-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2948 posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89344 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38828 BRD-K88086273 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2018 Lung squamous cell carcinoma_LUSC_TCGA-21-1070-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.60614 BRD-K96106084 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47943 LRIG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81322 Signaling by GPCR Reactome Pathways 2014 1.0 null santonin-3877 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE146612_2_v_0_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE140997_4_v_3_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null SUPM2 CCLE Cell Line Gene Expression Profiles 1.0 2.53633 biological_process GO Biological Process Annotations 2015 1.0 null Sarcoma_SARC_TCGA-DX-A7EL-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 FEZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2415 NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15096 callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03378 BRD-K01022714 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03884 TNFRSF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28211 HUT78 CCLE Cell Line Gene CNV Profiles -1.0 -1.85242 Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ursodeoxycholic acid-3105 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50462 BRD-K45537529 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04424 estradiol_oncorhynchus mykiss_gpl2096_gse5643 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HGC27 CCLE Cell Line Gene Expression Profiles 1.0 1.41852 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.10156 planum temporale, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12169 RMUGS CCLE Cell Line Gene CNV Profiles -1.0 -1.72359 YD8 CCLE Cell Line Gene Expression Profiles -1.0 -2.3142 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.859473 BRD-K73497584 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00648 CRCGN014_HEPG2_24H:C01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.60437 pheniramine-4012 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HS934T CCLE Cell Line Gene Expression Profiles -1.0 -1.61066 chr19_15816246_T_A_b38 GTEx eQTL 2025 1.0 4.47933 CRCGN011_HEPG2_24H:L04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.13505 CRCGN017_MCF10A.WT.HP_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.12465 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35673 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4824-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K29418729 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6154 cefalotin-6079 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BT474 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.770071 IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.76566 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66407 glibenclamide-1546 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null sensory perception of smell GO Biological Process Annotations 2023 1.0 null FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8117 HCT15 BioGPS Cell Line Gene Expression Profiles -1.0 -1.48393 GSE140997_2_v_7_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.40457 CFAP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3485 BRD-K95153427 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10522 TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4582 dacarbazine-4480 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MCF7 CCLE Cell Line Gene Expression Profiles -1.0 -1.4882 sparteine-4568 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ECC10 COSMIC Cell Line Gene Mutation Profiles 1.0 null ganciclovir-3368 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_HEPG2_48H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.06636 BRD-K02190643 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.73324 BRD-K35304243 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4712 TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10783 PF-01378883-00-6368 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K68134791 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4057 NCI-H2087 GDSC Cell Line Gene Expression Profiles 1.0 1.89394 GSE244710_1_v_2_srsf1_human RummaGEO Gene Perturbation Signatures 1.0 null G141 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02386 BRD-K74794014 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76559 HCC1806 COSMIC Cell Line Gene Mutation Profiles 1.0 null cimetidine-1884 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SEKI DepMap CRISPR Gene Dependency 1.0 2.32284 CRCGN017_MCF10A.TP53.M_24H:D22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.04045 BRD-K17885598 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30788 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04525 VRK1_knockout_64_GSE19329 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.65093 CRCGN015_HEPG2_48H:E22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.19601 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.846638 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC78 CCLE Cell Line Gene Expression Profiles 1.0 1.87612 BRD-K08759542 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01979 CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.787837 Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K36795325 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17665 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null signaling receptor activity GO Molecular Function Annotations 2015 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15248 TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.57402 RP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1202 SHSYSY+RA BioGPS Cell Line Gene Expression Profiles -1.0 -0.913992 BRD-A60487173 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07892 LOX-1_OE_GDS4262_433_human_HAECT - aortic endothelial cell line - 6 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null 496100392_HIP_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.22672 GLUL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22583 UT7 CCLE Cell Line Gene CNV Profiles 1.0 1.80141 CRCGN011_HEPG2_24H:L13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.769 MDAMB436 CCLE Cell Line Gene Expression Profiles -1.0 -1.68432 GSE140997_4_v_5_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null CRCGN016_MCF10A.TP53.M_24H:F14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.22927 HCC1569 CCLE Cell Line Gene Expression Profiles -1.0 -2.84482 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRCGN017_MCF10A.WT.HP_24H:P05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.60034 CRCGN016_MCF10A.TP53.M_24H:P16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.30158 OVCAR8 BioGPS Cell Line Gene Expression Profiles -1.0 -0.993272 TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5 primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.992754 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.85378 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IB-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03285 CRCGN015_MCF10A.WT.HP_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.05354 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5261-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K70050144 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21178 GFER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47354 PMC3348545-NIHMS263168-supplement-3.pdf-381-RFX1_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null BHLHE41 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9144 Intestinal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.505 Uroepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.811 BRD-K08929846 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04118 detection of stimulus GO Biological Process Annotations 2015 1.0 null Urinary bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.404 BRD-K79355381 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.86654 CRCGN016_MCF10A.TP53.M_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.113 BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4328 F36P CCLE Cell Line Gene CNV Profiles -1.0 -2.7968 UMUC7 DepMap CRISPR Gene Dependency 1.0 2.39542 BRD-K34957967 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5492 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1573 DepMap CRISPR Gene Dependency 1.0 3.0805 CRCGN008_HEPG2_24H:N20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0007 SNUC4 DepMap CRISPR Gene Dependency 1.0 4.51129 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU878 CCLE Cell Line Gene Expression Profiles 1.0 2.28938 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42944 SLR25 CCLE Cell Line Gene Expression Profiles -1.0 -1.67375 outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980981 BRD-K28764680 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41712 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97896 striatum_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09612 BRD-K88559334 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15743 isometheptene-5082 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K57894545 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.27718 UROtsa cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.506 Lung squamous cell carcinoma_LUSC_TCGA-66-2767-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K63364685 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1386 BRD-K07928699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6914 KCL22 DepMap CRISPR Gene Dependency 1.0 3.24873 BRD-K43341819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52016 imatinib_homo sapiens_gpl96_gds3043 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE131649_4_v_11_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null CRCGN015_MCF10A.WT.HP_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.92641 BRD-K77417197 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35402 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2626 levopropoxyphene-5083 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CRCGN012_HEPG2_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.01264 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14394 KMRC20 CCLE Cell Line Gene CNV Profiles -1.0 -1.62182 BRD-K45022385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84912 SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1584 CRCGN017_MCF10A.TP53.M_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.27891 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.892771 ACY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54119 JEG3 DepMap CRISPR Gene Dependency 1.0 2.15768 BRD-K07009788 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.91231 CRCGN016_MCF10A.TP53.M_24H:P12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.96927 BRD-K53104784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4911 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7427-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K02361314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.30281 BRD-K12132610 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29366 H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5323-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K05501176 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45223 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7485 signal transducer activity GO Molecular Function Annotations 2015 1.0 null CRCGN015_MCF10A.WT.HP_24H:C22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.09409 CRCGN015_MCF10A_48H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.30468 PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2003 JURKAT BioGPS Cell Line Gene Expression Profiles 1.0 0.863363 CRCGN013_HEPG2_24H:I13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.48993 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26298 BRD-K20895937 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45335 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EKVX BioGPS Cell Line Gene Expression Profiles -1.0 -1.87383 Wholebrain BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.24501 BRD-K49094605 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73712 NCVADR RES BioGPS Cell Line Gene Expression Profiles -1.0 -0.911659 16207381-Table1Sb GeneSigDB Published Gene Signatures 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20019 DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.73685 CRCGN016_MCF10A.WT.HP_24H:K10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.37305 CRCGN017_MCF10A.WT.HP_24H:N17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4707 TP53 ChEA Transcription Factor Targets 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.93209 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN016_MCF10A.WT.HP_24H:K11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.75891 LRFN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56189 HT29 CCLE Cell Line Gene Expression Profiles -1.0 -1.56896 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.919119 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26687 NALOXONAZINE-2HCL LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57478 NCI-H23 COSMIC Cell Line Gene Mutation Profiles 1.0 null Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.78812 BRD-K07825644 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0585 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04989 Prostate adenocarcinoma_PRAD_TCGA-G9-6333-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K84241565 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27074 U251 BioGPS Cell Line Gene Expression Profiles 1.0 1.15335 Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.147 PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR Rummagene Transcription Factor Associations 2026 1.0 null SNU245 CCLE Cell Line Gene CNV Profiles -1.0 -1.47932 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.835803 BRD-K30792491 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64628 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13081 Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20019 RTN4RL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36192 epitiostanol-4204 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K43700313 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27292 olfactory receptor activity GO Molecular Function Annotations 2025 1.0 null ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 125.11 dorsolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11554 Olfactory Signaling Pathway Reactome Pathways 2014 1.0 null H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851623 BRD-K34506374 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15167 clorsulon-1735 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE89729_0_v_1_ppard_human RummaGEO Gene Perturbation Signatures 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.87807 BRD-K76664579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22409 PK59 CCLE Cell Line Gene CNV Profiles 1.0 2.01878 HL-60 GDSC Cell Line Gene Expression Profiles -1.0 -1.57857 MALME 3M BioGPS Cell Line Gene Expression Profiles 1.0 1.271 GSPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22108 Grm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.586 demeclocycline-4267 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K01096898 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13966 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.875583 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.80325 sirolimus-5932 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null flufenamic acid-316 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PMC11923433-BLOOD_BLD-2024-025618-mmc2.xlsx-S3_Specific_genes_in_CEBPA-dm-Supplemental_Table_3_The_subtype-specific_enriched_marker_genes_in_CEBPA-dm_subtype_patients_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SFRP5_KO_GDS4988_27_mouse_gonadal white adipose tissue HFD GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SNU840 CCLE Cell Line Gene Expression Profiles -1.0 -1.95444 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100644_HIP_probable Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.69738 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BGC823 CCLE Cell Line Gene CNV Profiles 1.0 1.33876 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26458 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.952373 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.850733 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 BRD-K55142307 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79458 BRD-K91387865 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53659 SW579 CCLE Cell Line Gene CNV Profiles 1.0 1.94271 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.913466 Cecum cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.533 HT COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K44121468 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.03118 Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE119978,GSE180930_3_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null receptor activity GO Molecular Function Annotations 2015 1.0 null CRCGN014_HEPG2_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.90399 BRD-K15028515 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19906 CRCGN014_HEPG2_3H:J22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.5017 Prestwick-967-4250 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null TAL1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K36074653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09077 GSE140997_4_v_6_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null PA-TU-8902 COSMIC Cell Line Gene Mutation Profiles 1.0 null TIMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45018 SNRPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56577 MET_knockout_258_GSE25583 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.44392 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21072 NCIH2172 CCLE Cell Line Gene Expression Profiles 1.0 1.35638 Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09879 response to stimulus GO Biological Process Annotations 2015 1.0 null Glomus cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.62 CRCGN015_MCF10A_48H:P19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.69491 BRD-K28165728 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.95716 Bladder urothelial carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 BRD-K16093370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45608 Brain Lower Grade Glioma_LGG_TCGA-DU-8167-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K18452866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28398 hydroxyprogesterone LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26513 BRD-K72774661 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45241 outer CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19264 Aortic body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.593 BRD-K99807388 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.64694 EGR1 ChEA Transcription Factor Targets 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.912741 H4 DepMap CRISPR Gene Dependency 1.0 4.23742 icSARS-Cov_Day7_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.84355 BRD-K17020860 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43444 CRCGN015_MCF10A.WT.HP_24H:K10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.95205 Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A_48H:L01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.1529 SLC27A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8402 NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.4832 fulvestrant-2698 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K76176797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06037 MMP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17802 CRCGN016_MCF10A.TP53.M_24H:P20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.2065 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46706 BRD-K50884475 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04846 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -2.07535 L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34256 plicamycin LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3212 NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -1.55317 BRD-K71758378 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37248 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34758 GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0604 BRD-K14394756 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39054 GSE182680,GSE182683_7_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null 2,6-dimethylpiperidine-4363 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CRCGN015_MCF10A_48H:P13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.29982 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2025 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K42333498 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.76244 BRD-K69918256 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08324 Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RP-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FU97 CCLE Cell Line Gene CNV Profiles 1.0 2.19722 Iris smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.999 BRD-K85271599 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16453 BRD-K70042405 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68285 U-87-MG GDSC Cell Line Gene Expression Profiles -1.0 -1.59239 naringin-2425 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55711 BRD-K51681402 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.34171 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17803 NCIH292 CCLE Cell Line Gene Expression Profiles 1.0 1.51637 BRD-K66802550 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57666 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null naltrexone-5765 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CCDC142 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54606 ampyrone-1402 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874648 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN008_HEPG2_24H:J18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0728 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.86697 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50205 NCIH1623 CCLE Cell Line Gene Expression Profiles 1.0 1.61183 Ovarian surface epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.792 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06542 Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K56149020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27031 (+/-)-catechin-4255 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38672 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28921 BRD-K98432726 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41817 estradiol_mus musculus_gpl4134_gse23241 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K60932633 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0923 CRCGN016_MCF10A.TP53.M_24H:E19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.16495 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.963966 GSE187006_3_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03299 PBX1 ChEA Transcription Factor Targets 1.0 null LBH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77006 BRD-K78697404 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61504 ASCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66053 ZNF343 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.7484 dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44843 Detrusor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.128 SNU1196 CCLE Cell Line Gene CNV Profiles -1.0 -1.34631 NSA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25395 pallidohypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33928 GSE169617_1_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K45519638 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0614 BRD-K36697652 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.70483 BRD-K71622214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6584 496100526_TCx_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.49238 Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K61868194 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.9757 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.937093 SNU719 CCLE Cell Line Gene Expression Profiles 1.0 1.62759 TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.93655 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58324 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7276 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72614 Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K46619710 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64357 CRCGN015_HEPG2_48H:G19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3849 CRCGN012_HEPG2_24H:D09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.44728 BICR6 CCLE Cell Line Gene Expression Profiles 1.0 2.01923 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3461-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DLX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98905 TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.11929 icSARA deltaORF6_72Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.42432 JHUEM1 CCLE Cell Line Gene Expression Profiles -1.0 -2.07271 BRD-K73479560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14418 guanfacine-5621 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81G-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null APOBEC3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0602 molecular_function GO Molecular Function Annotations 2015 1.0 null CRCGN016_MCF10A.TP53.M_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3887 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.899932 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06294 superior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.826797 BRD-K17979415 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.3996 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9249 CRCGN015_HEPG2_48H:F04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.46224 Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A07861932 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06436 CRCGN015_HEPG2_48H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.91329 Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Macula densa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.033 mexiletine-4338 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OAW-28 COSMIC Cell Line Gene Mutation Profiles 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K38170103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0229 BRD-K72060858 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44256 Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K89194869 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00675 H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CCRT CEM BioGPS Cell Line Gene Expression Profiles 1.0 0.870484 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00084 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.21551 quinethazone-3793 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE119978,GSE180930_2_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47993 BRD-K36778976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30975 BRD-K03440991 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00743 ALEXANDERCELLS CCLE Cell Line Gene Expression Profiles 1.0 1.4467 TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0508 BRD-K57507729 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.01843 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08057 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.93734 BRD-K59263278 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38109 BRD-K44328896 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53155 dimethadione-3367 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HT-1376 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.194 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10973 BRD-K37780492 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.72115 H2AFZ ENCODE Transcription Factor Targets 1.0 null CRCGN016_MCF10A.TP53.M_24H:O13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.56175 tetraethylenepentamine-574 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CRCGN015_MCF10A.TP53.M_24H:N17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.3053 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.968942 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cyclobenzaprine-4252 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50536 FOXA1 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K33891642 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79604 JMURTK2 DepMap CRISPR Gene Dependency 1.0 2.01045 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8343 PMC9534852-41598_2022_20572_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_S4_Transcriptomic_data_related_to_AHR_function_considered_for_metabolic_reconstruction_model_generation_AHR Rummagene Transcription Factor Associations 2026 1.0 null SW837 CCLE Cell Line Gene CNV Profiles -1.0 -2.06756 seneciphylline-4238 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE218060_7_v_0_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.0 posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19713 CRCGN016_MCF10A.TP53.M_24H:C22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.26292 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN014_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.4431 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.927779 olfactory receptor activity GO Molecular Function Annotations 2023 1.0 null BRD-K36643302 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.32126 lomefloxacin-3723 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K94790210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53874 BRD-K40494117 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01994 MYCN-19997598-NEUROBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K80196706 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.93112 Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144 HES6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7863 ATF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16754 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58173 BRD-K58193973 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07465 BRD-K83143868 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05318 cell part LOCATE Predicted Protein Localization Annotations 1.0 null cisplatin_homo sapiens_gpl570_gse23553 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06294 GPCR downstream signaling Reactome Pathways 2014 1.0 null BRD-K12864860 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.37046 BRD-A40010674 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19643 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13426 sulfachlorpyridazine-2191 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TFE3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.375 CRCGN015_MCF10A.WT.HP_24H:P13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.33845 ONS76 DepMap CRISPR Gene Dependency 1.0 2.63557 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.956374 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6684 BRD-K25147028 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73249 MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5664 primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16757 EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.29046 MJ CCLE Cell Line Gene Expression Profiles -1.0 -1.83185 bladder GTEx Tissue Gene Expression Profiles 1.0 2.12745 BRD-K39692099 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12516 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tropine-5790 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SkeletalMuscle BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.18289 MFH-INO COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN015_MCF10A.TP53.M_24H:K10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4708 BRD-K32906083 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73468 HCC366 CCLE Cell Line Gene Expression Profiles 1.0 1.56147 RNF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81902 GSE243879_1_v_0_elapor1_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF135 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89956 RAB11FIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.433 Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN017_MCF10A.TP53.M_24H:K07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.52652 Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DUXA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89598 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null fursultiamine-2929 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.88285 ncih727 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.79 PMC9404532-NIHMS1788564-supplement-Supplementary_Tables_1-8.xlsx-Supp_Table_6-MYC_UP_V1_UP_MYC Rummagene Transcription Factor Associations 2026 1.0 null BRD-K30145193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82187 USF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6266 DLD1 DepMap CRISPR Gene Dependency 1.0 3.66614 BRD-K59535072 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3765 CITED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0504 H3K9me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYCN ChEA Transcription Factor Targets 1.0 null HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.880804 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06186 WM3772F DepMap CRISPR Gene Dependency 1.0 2.03945 BRD-K98408574 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88945 BRD-K69987634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07465 Lung adenocarcinoma_LUAD_TCGA-05-4250-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN017_MCF10A.WT.HP_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8933 MYCN-19997598-NEUROBLASTOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null TE14 CCLE Cell Line Gene Expression Profiles -1.0 -1.5244 SCARA5_Down Expression_GSE32323_611_human_Colorectal Cancer Cell lines GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.790609 BRD-K78612514 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3451 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43126 Olfactory transduction KEGG Pathways 2026 1.0 null Aspartate aminotransferase levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3024 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 thioproperazine-5791 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null WM983B CCLE Cell Line Gene Expression Profiles 1.0 2.08408 BRD-K16502264 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.87772 BRD-K46298622 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09666 C8166 DepMap CRISPR Gene Dependency 1.0 2.41689 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.9637 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.901581 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45P-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K74870161 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15261 BRD-K80225716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07382 SW1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.7843 TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3587 BRD-K97707303 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46358 BRD-K26734305 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43858 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE119978,GSE180930_6_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Small intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.113 Oral cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.767 GSE182680,GSE182683_5_v_12_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Retinitis pigmentosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.142 SLC30A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61338 496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01834 BRD-K02337960 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.48312 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.198 CRCGN015_MCF10A.WT.HP_24H:K11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.14219 GSE239844_1_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K81293413 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26985 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8ML-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K42799692 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04026 BRD-K24554824 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66325 BRD-K22069962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5531 BRD-K57786075 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34774 BRD-K71499752 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06099 CRCGN015_MCF10A.WT.HP_24H:D24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.30774 HN CCLE Cell Line Gene CNV Profiles 1.0 2.51556 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.835326 NB6 COSMIC Cell Line Gene Mutation Profiles 1.0 null YAPC DepMap CRISPR Gene Dependency 1.0 2.68976 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.911406 postcentral gyrus, left, bank of the posterior central sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17264 TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.9174 nitrendipine-6304 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.862245 BRD-K81757081 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84656 BRD-K20071915 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.94149 BRD-K41746201 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03466 UMC-11 GDSC Cell Line Gene Expression Profiles 1.0 1.54225 SNU16 DepMap CRISPR Gene Dependency 1.0 3.11779 H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09879 BRD-K67229323 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54985 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31753 BRD-K50726251 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.19431 CRCGN015_MCF10A_48H:M22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.07851 Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K66659401 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16421 BRD-K98510376 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57393 BRD-K34158806 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15053 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE80537_0_v_2_adhfe1_human RummaGEO Gene Perturbation Signatures 1.0 null Prestwick-674-2179 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996376 CD14+_Monocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.890449 etifenin-3998 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SFRP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52761 BRD-K41829399 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38352 BRD-K03141963 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64357 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2023 1.0 null BRD-K17514980 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4735 MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0845 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MF-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null CRCGN016_MCF10A.TP53.M_24H:I11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.57475 496100475_TCx_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.79071 Uterine Carcinosarcoma_UCS_TCGA-NF-A5CP-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A63704386 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33809 H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC2814 CCLE Cell Line Gene Expression Profiles 1.0 1.40196 OV90 CCLE Cell Line Gene CNV Profiles -1.0 -1.59028 BRD-A02612852 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.8894 BRD-K34858602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12288 BRD-K53889798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0345 Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precuneus, left, superior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.841333 CRCGN017_MCF10A.WT.HP_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.66055 BRD-K72717797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00248 BRD-K64537490 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35569 Psmb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.701 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48115 BRD-K41307047 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5071 496100516_FWM_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.49515 BRD-A24524033 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07304 G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null Appendix BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.00298 BRD-K50443235 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.08803 Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ciclacillin-3882 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CRCGN014_HEPG2_3H:P04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.58764 PLCPRF5 DepMap CRISPR Gene Dependency 1.0 2.34035 Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A.TP53.M_24H:K08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.16815 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.5163 HCC1937 CCLE Cell Line Gene CNV Profiles 1.0 1.43604 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.825509 MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2227 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70955 BRD-K27458941 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63909 BRD-K81925504 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13281 BRD-K96449536 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.65117 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11637 altretamine-5688 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CRCGN011_HEPG2_24H:C24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.55395 EW-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-A08191729 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64527 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35219 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0977 BRD-K68605096 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31278 CRCGN017_MCF10A.WT.HP_24H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.8317 BRD-K11804865 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24733 BRD-K81660107 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13715 Ethanolamine ammonia-lyase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.926 cuneus, left, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.916245 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16753 BRD-K56283394 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3638 BRD-K97445906 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.85925 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.602 Iris sphincter muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.133 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12464 CRCGN015_HEPG2_48H:H13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.7752 SUM159PT DepMap CRISPR Gene Dependency 1.0 2.23299 hydrochlorothiazide-6625 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K18709210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01573 BRD-K34456337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10512 BRD-K35978846 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2161 CREB3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86677 BRD-K89325755 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29106 BRWD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67141 dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.002 BRD-K90255725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18541 Skmes TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.98 JAR DepMap CRISPR Gene Dependency 1.0 2.42333 Olfactory Signaling Pathway Reactome Pathways 2024 1.0 null BRD-K77594363 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34124 H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 2,6-dimethylpiperidine-3806 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K67905771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42941 BRD-K79329532 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.14949 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K23836639 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07165 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null BRD-K01314849 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17712 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K87080069 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52468 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958393 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.55325 BRD-K66963616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19308 Lung adenocarcinoma_LUAD_TCGA-50-6593-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THBD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50735 CRCGN016_MCF10A.TP53.M_24H:P18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.62292 BRD-K54066059 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20343 BRD-K21201014 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21617 BRD-K31883758 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00234 CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 496100467_FWM_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 9.70486 NCI-H64 GDSC Cell Line Gene Expression Profiles 1.0 1.87202 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06131 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4709 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A89554862 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2229 Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K11730256 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.15972 Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K92444813 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14204 SKLU1 CCLE Cell Line Gene Expression Profiles -1.0 -1.56412 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null plasma membrane GO Cellular Component Annotations 2015 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46842 Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.103 CRCGN014_HEPG2_24H:K13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.6515 Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09879 BRD-K06614363 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11979 DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null MCF7 DepMap CRISPR Gene Dependency 1.0 2.15774 BCAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04989 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1721 naftifine-7032 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ZNF280B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68408 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.7387 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nialamide-3871 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LMSU CCLE Cell Line Gene Expression Profiles -1.0 -1.63557 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-MYC_UP_V1_UP-Ensemble_gene_ID_MYC Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100621_TCx_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.63074 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945788 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.83996 GSE188458_2_v_1_hydrogen peroxide_human RummaGEO Drug Perturbation Signatures 1.0 null SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.907018 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4956 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29736 OCIM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.55195 Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K21927299 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72463 H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2087 DepMap CRISPR Gene Dependency 1.0 3.03757 Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN017_MCF10A.WT.HP_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.5697 FREM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45262 CRCGN011_HEPG2_24H:J02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.03075 molecular transducer activity GO Molecular Function Annotations 2015 1.0 null BRD-K13461720 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35401 Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN016_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.80822 KATOIII CCLE Cell Line Gene CNV Profiles -1.0 -1.85395 Lung GTEx Tissue Gene Expression Profiles 2023 1.0 1.52871 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MG-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K54362440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09816 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5493 496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.2785 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.47241 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.93523 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.857402 H4 CCLE Cell Line Gene CNV Profiles 1.0 1.67281 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.968313 CRCGN015_MCF10A_48H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.757 INMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27823 Ovarian surface epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.044 CRCGN015_MCF10A.TP53.M_24H:C23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.597 BRD-K60907484 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0008 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22994 BB30-HNC GDSC Cell Line Gene Expression Profiles -1.0 -1.73755 BRD-K11942486 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79071 SAMHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9993 BRD-K18268126 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66683 BRD-K24719325 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27226 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.01094 BRD-K98961458 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.3356 USF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19076 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12604 stomach BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.846443 Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.70652 Transitional cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.201 BRD-K17405621 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03285 Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3144 ZM-226600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48269 torasemide-5057 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K89364982 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1671 MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0496 SNU869 CCLE Cell Line Gene Expression Profiles 1.0 1.64376 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10875 CRCGN008_HEPG2_24H:I06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0227 GSE135350_3_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.945149 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.11421 CTAGE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61345 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.3183 erastin-6369 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4787-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.74775 Chemoreceptor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.578 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.41 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.3299 KLM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.14704 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.969695 BRD-K77150932 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18481 BRD-K78712486 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01562 SGTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65792 ZNF235 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43123 arsenic trioxide_homo sapiens_gpl201_gse48441 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tubocurarine chloride-1738 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PF-00875133-00-5928 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PMC4905481-oncotarget-07-11397-s003.xlsx-Pinin_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null GPCRs, Class A Rhodopsin-like(Homo sapiens) WikiPathways Pathways 2014 1.0 null CRCGN017_MCF10A.TP53.M_24H:K23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.2288 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.968313 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MR-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3678 rifamycin-sv LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23287 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MGMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00767 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35673 BRD-K69564473 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27484 RI1 DepMap CRISPR Gene Dependency 1.0 2.00763 BRD-K54650634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35464 BRD-K87595216 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39775 GSE148200_4_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null RS11846 BioGPS Cell Line Gene Expression Profiles 1.0 0.889231 PMC10709143-41556_2023_1271_MOESM10_ESM.xls-Up_hPSC_PAX7-Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null SLC45A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70849 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31751 CRCGN010_HEPG2_24H:B11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.14524 CRCGN015_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.76744 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.62522 valproic acid-4433 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE239844_7_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE225869_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null CD151 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07706 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53588 496100670_TCx_probable Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.30923 TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3264 BRD-K69375224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41757 Sensory Perception Reactome Pathways 2024 1.0 null plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null GSE94849_7_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7911-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN017_MCF10A.WT.HP_24H:O19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.2195 BRD-K95651150 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13412 MDAMB415 CCLE Cell Line Gene CNV Profiles -1.0 -1.34828 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.912741 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 Dhori Virus_48Hour_20090954_GSE17400 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.23834 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1516 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.893166 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 alpha-yohimbine-5800 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GNPTAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64582 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 lithocholic acid-3816 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Urethra TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.113 Sarcoma_SARC_TCGA-DX-A6YZ-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RELA_01_80 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.63554 GSE223893_4_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.37279 JSC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSK3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57889 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8308 496100647_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.91914 Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.85536 Prostate adenocarcinoma_PRAD_TCGA-HC-7817-01B-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A28153253 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21122 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.25583 EBLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43944 CRCGN015_HEPG2_48H:J24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.47098 NB12 GDSC Cell Line Gene Expression Profiles -1.0 -1.85127 A375SKINCJ1 DepMap CRISPR Gene Dependency 1.0 3.11094 CRCGN015_HEPG2_48H:H19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.16306 BRD-K68463857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04598 CRCGN017_MCF10A.WT.HP_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.48525 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66277 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.958321 DYNLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49745 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22312 precentral gyrus, right, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.934996 OSR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8216 ZNF750 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91298 SPIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33099 superior parietal lobule, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.828206 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42229 oxyphenbutazone-6160 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8305-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH82 CCLE Cell Line Gene CNV Profiles 1.0 1.33511 NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.625 CD105+_Endothelial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.836501 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 BRD-K76173551 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10032 BRD-K17062413 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.14075 BRD-K60848736 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01276 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59233 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66322 BRD-K07762528 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00306 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-4J-AA1J-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18839 BRD-A17687311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11031 trichostatin A-5802 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K35124958 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16949 Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LB2241-RCC GDSC Cell Line Gene Expression Profiles -1.0 -2.17265 HCC70 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.6842 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58324 BRD-K12612468 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73205 LLPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64776 BRD-K60781525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14997 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30993 CRCGN016_MCF10A.TP53.M_24H:K10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.10612 ARHGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55757 precentral gyrus, right, bank of the central sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913691 CRCGN017_MCF10A.TP53.M_24H:E09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3918 BRD-K73025859 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05727 Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A42536341 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67285 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02689 MV411 DepMap CRISPR Gene Dependency 1.0 3.16814 valproic acid-6181 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88995 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80349 BRD-K28159131 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08493 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28365 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.08565 BRD-K63584084 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3409 C2orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92296 superior temporal gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.902245 PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null BRD-K50367303 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15748 NCIH1581 DepMap CRISPR Gene Dependency 1.0 2.74743 Nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.352 BRD-K25649596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20723 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27116 BRD-K70856965 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97865 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.97483 methacholine chloride-5773 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CAL33 CCLE Cell Line Gene Expression Profiles 1.0 1.66664 BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.859597 KASUMI1 DepMap CRISPR Gene Dependency 1.0 3.52466 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843178 BRD-K31297909 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1011 BRD-K52731958 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33465 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851623 CRCGN016_MCF10A.TP53.M_24H:H09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.80063 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57477 BRD-K62152527 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20976 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K52932858 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.50944 CRCGN016_MCF10A.TP53.M_24H:M12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.32393 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55522 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09879 Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K72936860 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24281 RIOK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75027 BRD-A16313205 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15883 COLO-783 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K95688447 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32746 Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE140997_4_v_8_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.909882 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6936 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null Signal Transduction Reactome Pathways 2014 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0061 CRCGN015_MCF10A.WT.HP_24H:C24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.66151 Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_HEPG2_48H:O10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.64028 HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.89762 BRD-K45713337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35286 BRD-K92891227 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11299 BRD-K18888894 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1436 Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09467 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08878 J82 GDSC Cell Line Gene Expression Profiles -1.0 -1.46275 CLOCK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0579 hsa-miR-26b-5p MiRTarBase microRNA Targets 1.0 null BRD-A64523751 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39502 BRD-K91421454 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07962 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.77533 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null clopamide-1605 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.900302 BRD-K68160857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54466 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.5241 BRD-K16063772 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2744 Sarcoma_SARC_TCGA-K1-A42W-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K74515526 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.8676 FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 104.271 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.912741 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05196 lorglumide-6456 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06186 CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEXB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.3704 ACHN BioGPS Cell Line Gene Expression Profiles -1.0 -1.47069 OVSAHO CCLE Cell Line Gene CNV Profiles 1.0 1.89801 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13363 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38434 BRD-K91897530 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14982 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.74245 SP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936473 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58324 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01489 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00234 Lung squamous cell carcinoma_LUSC_TCGA-52-7811-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892545 HEL9217 CCLE Cell Line Gene Expression Profiles -1.0 -2.05885 BRD-K07740919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45255 BRD-K33869336 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01766 BRD-K51461946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23325 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4892-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K17570530 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16957 ESR1 JASPAR Predicted Transcription Factor Targets 1.0 null NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 BRD-K16518464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17651 CRCGN017_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.98395 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2051 NCI-H1944 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.865261 KHM1B CCLE Cell Line Gene CNV Profiles 1.0 1.38176 letrozole-4240 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CRCGN013_HEPG2_24H:M13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.12037 BRD-K65320638 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79226 BRD-K62148271 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25691 496100448_TCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.1036 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.05969 BRD-K71213946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25821 BRD-K91361836 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22076 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14073 EPHB2_drugactivation_228_GSE26523 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.85352 Olfactory nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.934 g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null HCC2450 DepMap CRISPR Gene Dependency 1.0 2.54657 santonin-4353 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-3614-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 BRD-K16673836 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.1099 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K62318087 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.44584 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.952716 BRD-K45343543 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08101 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.62848 Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMSB4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83614 CRCGN015_MCF10A.TP53.M_24H:C22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.2067 CRCGN016_MCF10A.WT.HP_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.67161 BRD-K58932103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31208 BRD-K14207150 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81 probenecid-2825 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null striatum_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.20252 BRD-K47878187 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59926 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.49216 BRD-K83553001 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28558 ML1 CCLE Cell Line Gene Expression Profiles -1.0 -1.46712 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927838 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27013 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20843 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null BRD-K81181894 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46272 NCI-H716 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.686 frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.90955 YY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78275 P31FUJ DepMap CRISPR Gene Dependency 1.0 2.61865 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01438 SNU1076 CCLE Cell Line Gene CNV Profiles -1.0 -2.30907 Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory receptor InterPro Predicted Protein Domain Annotations 1.0 null BRD-K97421379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69021 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E8-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K21753319 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05677 BRD-K38350115 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35676 BRD-K70594121 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30393 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.968313 GSE148200_0_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null bupropion-5782 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Nucleus solitarius TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.522 BRD-K61485947 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79294 CORL47 CCLE Cell Line Gene Expression Profiles 1.0 1.79161 sensory perception of smell GO Biological Process Annotations 2025 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5748-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3045 BRD-K95591629 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01762 BRD-K37584517 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0292 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3201 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SH2B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82362 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.71203 BRD-K57357721 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13558 PHF21B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20959 COLO-824 COSMIC Cell Line Gene Mutation Profiles 1.0 null amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.892404 Bladder disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.562 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A.TP53.M_24H:G06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.508 CD71+_EarlyErythroid BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.01996 CRCGN016_MCF10A.TP53.M_24H:C18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.58649 CRCGN016_MCF10A.TP53.M_24H:O15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.82931 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K41207293 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14935 CRCGN015_MCF10A_48H:K11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.1701 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.24507 GSE148200_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.973836 dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.67983 BRD-K27849471 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07143 BRD-K08534346 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2674 HUPT3 CCLE Cell Line Gene CNV Profiles 1.0 1.71716 Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KQ-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.26602 BRD-K89376690 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46716 BRD-K34254821 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03186 Urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.387 outer CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.836461 medial intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.996882 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IPC298 CCLE Cell Line Gene CNV Profiles 1.0 1.60686 GSE223908,GSE223909_1_v_3_serpinb3_human RummaGEO Gene Perturbation Signatures -1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19909 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3157 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65899 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03023 HUPT3 CCLE Cell Line Gene Expression Profiles 1.0 3.18243 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.950157 BRD-K00620786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.20111 TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7362 ANAPC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03596 BRD-K90092568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21702 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06294 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.908188 BRD-K02747732 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03129 CRCGN017_MCF10A.TP53.M_24H:G12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.96626 BRD-K90361987 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10019 REH DepMap CRISPR Gene Dependency 1.0 3.00964 SNU1076 DepMap CRISPR Gene Dependency 1.0 2.7388 E2F1-17053090-MCF7-human ChEA Transcription Factor Binding Site Profiles 1.0 null BON-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.653 HK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26619 BT-20 GDSC Cell Line Gene Expression Profiles -1.0 -1.42706 BRD-K19830171 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03604 Iris TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.865 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.41727 cell part GO Cellular Component Annotations 2015 1.0 null TMEM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14844 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996376 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844015 Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null (-)-isoprenaline-4495 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ONDA9 DepMap CRISPR Gene Dependency 1.0 2.72045 CRCGN011_HEPG2_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.136 2313287 DepMap CRISPR Gene Dependency 1.0 2.77446 BRD-K69942587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40256 BRD-K07588901 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45518 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6083 CRCGN015_MCF10A.WT.HP_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.14163 COLO-704 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08554 Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.437 basal nucleus of Meynert Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11374 membrane GO Cellular Component Annotations 2015 1.0 null P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K16802067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42005 PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9037 BRD-A19962819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21133 BRD-K92022897 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40326 detection of chemical stimulus GO Biological Process Annotations 2015 1.0 null BRD-K69491845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42739 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN016_MCF10A.TP53.M_24H:E17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.02638 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.850645 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.6082 BRD-K28656917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72639 Olfactory tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.932 CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.44318 Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855196 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58153 BRD-K71420819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24199 BRD-K77697725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08027 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.84711 BRD-K01577807 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13016 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.967283 valproic acid-5569 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DFCI024 CCLE Cell Line Gene Expression Profiles 1.0 2.43983 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86138 XRCC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77053 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26113 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-11A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K68916730 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87134 GSE158969_1_v_2_trastuzumab_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K38282015 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44173 hydroxytoluic-acid LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28571 496100586_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57207 Lung squamous cell carcinoma_LUSC_TCGA-43-8118-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN012_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.2552 BRD-K02393180 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.77485 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.902293 NCIH2405 CCLE Cell Line Gene CNV Profiles -1.0 -1.48376 propofol-3048 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K98976117 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20754 GSE245778_1_v_0_runx1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE94849_1_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Urinary bladder cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.29 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.012 BRD-K03713632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06512 BRD-K90316899 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14106 BRD-K22584556 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.28852 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K89436979 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.53093 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.00588 GSE178340_7_v_2_carfilzomib_human RummaGEO Drug Perturbation Signatures -1.0 null folic acid-1790 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K47164766 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27471 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K75143842 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.90764 Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K15898103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14744 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.56738 BRD-K61278167 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67335 integral component of membrane GO Cellular Component Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5767-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.984402 BRD-K83895653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89551 CRCGN010_HEPG2_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.48556 Apical cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.733 cingulate gyrus, retrosplenial part, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.837927 BRD-K40432489 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58793 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.968313 BRD-K14909006 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05111 BRD-K38211037 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00055 BRD-K82570855 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53251 NCIH520 DepMap CRISPR Gene Dependency 1.0 3.08739 CRCGN016_MCF10A.TP53.M_24H:E20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.03522 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K71177762 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24626 MYC_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null MG63 CCLE Cell Line Gene CNV Profiles 1.0 1.68239 BRD-K60905390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7434 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8315-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9391 BRD-K26435104 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13838 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.93304 BRD-K38984040 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16139 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K15775306 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65069 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.7233 GCM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9328 JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 1.67526 MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3731 inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12928 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.899133 BRD-K63058274 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08073 CRCGN015_MCF10A.TP53.M_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.6817 BRD-K82460510 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57009 BRD-K91624805 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68215 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29683 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VB-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A_48H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.45553 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03285 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03937 quercetin-4264 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null TRUB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.44171 CRCGN015_HEPG2_48H:P19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.12453 X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17952 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null BRD-K20733942 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53849 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4281 primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.932628 posterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.878045 membrane part GO Cellular Component Annotations 2015 1.0 null A204 BioGPS Cell Line Gene Expression Profiles 1.0 1.01647 BRD-K82784817 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.78968 CABLES1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9927 BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9947 BRD-K05475322 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01834 ECC10 CCLE Cell Line Gene Expression Profiles -1.0 -2.61697 CRCGN015_MCF10A.TP53.M_24H:P20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.01665 RELA_DN.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null SLR20 CCLE Cell Line Gene CNV Profiles 1.0 1.41143 Expression and translocation of olfactory receptors Reactome Pathways 2024 1.0 null SNU46 CCLE Cell Line Gene Expression Profiles -1.0 -1.56237 BRD-K69093885 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3309 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0404 CRCGN016_MCF10A.WT.HP_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.80245 GSE80537_3_v_2_adhfe1_human RummaGEO Gene Perturbation Signatures 1.0 null BRD-K61912055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33878 PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-MYC_UP_V1_UP-Gene_name_MYC Rummagene Transcription Factor Associations 2026 1.0 null BRD-K64836560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10457 MESOV DepMap CRISPR Gene Dependency 1.0 2.64663 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BC-3 GDSC Cell Line Gene Expression Profiles 1.0 1.88823 3-nitropropionic acid-6372 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE221386_2_v_0_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null Bladder carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.03 KMS26 DepMap CRISPR Gene Dependency 1.0 3.92173 CRCGN015_HEPG2_48H:D17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.51294 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K61753872 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14931 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UG-01A-32R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3014 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26113 BRD-K35717699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1692 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 CRCGN015_HEPG2_48H:J23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.51683 PWWP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7444 BRD-K20454972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23374 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null BRD-K63997411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24246 CRCGN016_MCF10A.TP53.M_24H:K12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.46924 CRCGN016_MCF10A.TP53.M_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.6539 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null wortmannin-2703 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.63003 T3M10 CCLE Cell Line Gene CNV Profiles 1.0 1.46378 RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8109 TAL1 ENCODE Transcription Factor Targets 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940875 CTIP_DN.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Melanophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.505 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4881-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN016_MCF10A.TP53.M_24H:P14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.53408 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null CRCGN012_HEPG2_24H:D07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.6552 BRD-K26904107 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12998 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40071 STAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32101 Acute Myeloid Leukemia_LAML_TCGA-AB-3008-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50536 GPCRs class A rhodopsin like WikiPathways Pathways 2024 1.0 null NCIH28 CCLE Cell Line Gene Expression Profiles -1.0 -1.79759 TGBC24TKB GDSC Cell Line Gene Expression Profiles 1.0 2.0734 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null nipecotic acid-3121 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K85633971 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20507 Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57234 signal transduction GO Biological Process Annotations 2015 1.0 null BRD-K01100412 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09506 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.826921 Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TANOUE DepMap CRISPR Gene Dependency 1.0 2.14443 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_7Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.13448 flucloxacillin-6507 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K05127596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00894 H3-3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00118 subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00464 E2F1-17053090-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K16079077 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52606 CRCGN016_MCF10A.TP53.M_24H:C10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.11889 LB2518-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN014_HEPG2_24H:D07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.6648 BRD-A63759745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43585 BRD-K02837259 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.54707 Perturb_3935_KO_TFAP2A_SRP273704 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2025 1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.946 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46913 BRD-A01717111 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21575 BRD-K26863838 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.13545 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.866 HEP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.826921 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K35422614 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50739 LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1437 BRD-K74289419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20926 Lung squamous cell carcinoma_LUSC_TCGA-58-8393-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K67200393 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00938 BRD-K86638309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29816 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851623 Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1944 CCLE Cell Line Gene CNV Profiles -1.0 -2.43152 LM-1685-253 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF Rummagene Transcription Factor Associations 2026 1.0 null primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18503 KIJK DepMap CRISPR Gene Dependency 1.0 2.24068 anterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.63219 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07945 BRD-K73357447 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1162 UterusCorpus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.904924 LIVF001-019 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.35856 FGF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17104 BRD-K65438558 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13932 BRD-K21059010 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27539 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7891-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.869423 FARAGE DepMap CRISPR Gene Dependency 1.0 3.82979 BRD-K36104357 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59911 PCI-30 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT DepMap CRISPR Gene Dependency 1.0 2.9407 Leukemia_promyelocytic-HL-60 BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.830662 BRD-K86855109 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20728 MG63 DepMap CRISPR Gene Dependency 1.0 2.11321 BRD-K60430317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02358 MLH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72213 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 BRD-K65733046 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02544 EVSA-T COSMIC Cell Line Gene Mutation Profiles 1.0 null outer CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.868951 ICAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89788 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4323 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles -1.0 -1.54267 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09452 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 FBXW8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69278 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.0247 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61865 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.826921 EZH2 ENCODE Transcription Factor Targets 1.0 null BRD-K06237859 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7185 BRD-K80462316 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30301 JJN3 DepMap CRISPR Gene Dependency 1.0 2.82245 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975841 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5195 CRCGN015_HEPG2_48H:C01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.69384 PMC10247733-41408_2023_863_MOESM2_ESM.pdf-358-ONECUT3_ONECUT3 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K77343050 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58523 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_12Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.67132 BRD-K02934881 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16278 BRD-K40509138 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.3422 Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K69791255 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58437 OVTOKO COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN014_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.0365 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.74252 CRCGN014_HEPG2_24H:L18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.59104 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6561 H3K27me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K04614055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05788 BRD-K87879912 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24416 Lung adenocarcinoma_LUAD_TCGA-MP-A4T9-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WM793B COSMIC Cell Line Gene Mutation Profiles 1.0 null MV-4-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.936729 OCI-AML5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65961 CRCGN015_MCF10A.WT.HP_24H:P22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.29541 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.982281 BRD-K77203880 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46534 BRD-K97468369 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42095 SLVL DepMap CRISPR Gene Dependency 1.0 3.91866