association	dataset	threshold value	standardized value
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01302
Perturb_5550_KO_FBXO11_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.34735
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934026
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58468
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82835
KATOIII	DepMap CRISPR Gene Dependency	1.0	3.05587
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0288
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04599
Perturb_9923_KD_PTBP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.8115
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855355
Perturb_637_KO_SOX4_ERP117895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.60565
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10165_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.83386
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0435
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6296
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4071
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.920858
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH810	CCLE Cell Line Gene CNV Profiles	1.0	1.51461
MDAMB436	DepMap CRISPR Gene Dependency	1.0	2.11075
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4976
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483986
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.12703
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.34941
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6115
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
Perturb_9902_KD_RPS10_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.33492
ECC12	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3196
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.43972
MOLP8	CCLE Cell Line Gene CNV Profiles	1.0	1.64024
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	2.71528
SPI1	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10048_KD_NONO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61825
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07417
KOSC2	DepMap CRISPR Gene Dependency	1.0	2.3362
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82703
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-2.7169
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5826
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.105
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.783
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9883_KD_CPEB4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.30449
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08775
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93079
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9857_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.75914
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9850_KO_PTPN2_SRP214323	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.56518
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863201
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
MEL270	DepMap CRISPR Gene Dependency	1.0	2.64456
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5926
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27459
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8309
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.828096
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_10138_KO_PRPF40B_SRP197235	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.01264
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865432
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051093
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07917
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.98979
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941476
MMAC	DepMap CRISPR Gene Dependency	1.0	3.90442
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863201
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11784
Perturb_10027_KD_APOBEC3C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.85532
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6473
Perturb_9926_KD_SRSF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.69613
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9647
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	2.00812
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.920713
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040202
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92477
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9171
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.965501
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34198
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10095_KD_AGO2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.90489
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4364
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6984
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
C32	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7017
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10007_KD_HNRNPA1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.3604
Perturb_9903_KD_SLTM_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38342
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7844
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6849
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9887
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0822
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.122
LN443	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39376
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992902
E2F4	ENCODE Transcription Factor Targets	1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855355
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21727
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34065
membrane part	GO Cellular Component Annotations 2015	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.58204
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_10116_KD_PAPOLA_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.84389
SNU410	DepMap CRISPR Gene Dependency	1.0	2.81077
Perturb_9854_KD_LUC7L3_ERP124746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.24197
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.382
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4006
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18271
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4218
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886907
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.862887
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Mean spheric corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
Prp19 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2786
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5374
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2141
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3295
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44504
Perturb_9867_Mut|KD_SRSF2_SRP368113	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.06991
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875871
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987912
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41336
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00385
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32943
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07417
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.876891
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.38618
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.379
Narcolepsy	HuGE Navigator Gene-Phenotype Associations	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66769
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0777
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13487
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11784
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884361
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6789
Red Blood Cell Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871738
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6869-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8577
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.750388
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9079
H3K36me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NZM42	DepMap CRISPR Gene Dependency	1.0	3.59641
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2076
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20086
Perturb_10672_KO_Gata2_SRP212686	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039496
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1111
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6494
Perturb_3253_KD_RPS19_SRP092068	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.22649
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0563
NKX3-1	JASPAR Predicted Transcription Factor Targets	1.0	null
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60267
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OE21	DepMap CRISPR Gene Dependency	1.0	3.1492
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4878-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8856
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6296
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
cd4.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.12495
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00045
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75837
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8705
Mushroom body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34376
immune system disease	GWASdb SNP-Disease Associations	1.0	0.159187
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3408
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1876	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20224
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.996454
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6836
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2091
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3709
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pulmonary edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74641
molecular_function	GO Molecular Function Annotations 2015	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
LPS6	DepMap CRISPR Gene Dependency	1.0	3.04869
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1335
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2965
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.21
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03283
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.25669
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01936
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051011
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2277
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9182
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.044066
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65383
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.2
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4911
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3262_KO_VHL_SRP337931	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.40379
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5093
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12883
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13263
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.50086
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887315
Perturb_16602_KO_Alkbh5_SRP125927	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74494
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	1.51935
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9872
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	1.84571
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.832332
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894661
Perturb_9970_KD_WDR43_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.82
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59218
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21865
Perturb_10039_KD_UBE2L3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.09824
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0381
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1652
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06425
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE139455_4_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93141
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10130_KD_GATA1_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.19525
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73885
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.19994
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6561
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8938
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61723
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5666
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990731
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84377
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2843
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10002_KD_FTO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.12391
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3317
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09181
Perturb_10119_KD_TAF15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.7985
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_10129_KD_eHDAC6_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.08153
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3579
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	2.43125
icSARA deltaORF6_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.5597
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46367
KDM4A	ENCODE Transcription Factor Targets	1.0	null
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.99952
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	1.76127
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74927
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034209
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.12703
Signal Transduction	Reactome Pathways 2014	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60267
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
RH4	DepMap CRISPR Gene Dependency	1.0	2.03431
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20203
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.32785
SNU213	DepMap CRISPR Gene Dependency	1.0	2.90545
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3126
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3997_KO_HIC2_SRP317427	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.41922
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27459
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13396
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3819
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6591
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29303
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0481
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5516
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60397
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03758
Whipple's Disease_macrophage_GSE16180	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.32425
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8501
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3662
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970965
Perturb_5551_KO_FBXO11_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mean reticulocyte volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00969
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07298
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.879
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.36041
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53288
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65367
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T98G	DepMap CRISPR Gene Dependency	1.0	2.21129
IST-SL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10168_KO_TOP2A_SRP297586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5503
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4192
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3589
Perturb_631_KO_SOX4_ERP117895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.13312
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2328
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7541
Sensory Perception	Reactome Pathways 2024	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06568
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21924
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1327
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05558
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6612
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OPM2	CCLE Cell Line Gene CNV Profiles	1.0	1.98558
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.983
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68243
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65035
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
peripheral vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.12703
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4611
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SKMM2	DepMap CRISPR Gene Dependency	1.0	3.22
SNU620	DepMap CRISPR Gene Dependency	1.0	4.92913
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.049901
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.049901
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
deltaEF1	MotifMap Predicted Transcription Factor Targets	1.0	null
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846414
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893479
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2344
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09329
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0079
Perturb_9907_KD_EIF2S2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2352
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3031
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.4706
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864311
MJ	DepMap CRISPR Gene Dependency	1.0	2.41232
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60988
GSE131649_4_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7695
Spleen volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.12218
RL	DepMap CRISPR Gene Dependency	1.0	3.68572
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894055
TGFBR2_knockout_294_GSE36778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.74805
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54849
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09482
Prostate adenocarcinoma_PRAD_TCGA-CH-5791-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5664
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3733
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3809
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07417
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.034125
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45634
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
170MGBA	DepMap CRISPR Gene Dependency	1.0	2.22815
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4884
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.03678
EOL1	DepMap CRISPR Gene Dependency	1.0	2.49791
Perturb_635_KO_SOX4_ERP117895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.37166
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55152
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9884_KD_DDX47_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8132
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847222
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04599
SNU46	DepMap CRISPR Gene Dependency	1.0	2.4246
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-526-POU2F1_POU2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3002
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65659
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20086
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2218
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5975
GAMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35024
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0541
REH	DepMap CRISPR Gene Dependency	1.0	4.86298
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Perturb_9967_KD_SRPK2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.96942
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54802
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20986
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2468
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8357
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8838_OE_MLLAF4_SRP293797	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.88843
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1619
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.28151
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2589
Perturb_9892_KD_PPIG_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.66995
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_625_KD_IGF2BP3_SRP068523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.6412
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.971
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00045
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3022
Perturb_9922_KD_PCBP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2987
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7114
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.5743
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.02797
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.54185
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5493
COV644	DepMap CRISPR Gene Dependency	1.0	2.9327
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.897113
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055404
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8407
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93849
Bone_Marrow-erythrocyte	Tabula Sapiens Gene-Cell Associations	1.0	1.39865
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886907
ME-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	2.5771
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2335
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.911
Perturb_9972_KD_BCLAF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.6379
TM31	DepMap CRISPR Gene Dependency	1.0	2.86557
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4396
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932517
Perturb_10034_KD_PUF60_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.50247
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85845
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5603
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.727
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37824
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_14615_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.15221
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	2.28406
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4141
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.894
Perturb_9858_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.41784
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44692
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60815
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Signaling by GPCR	Reactome Pathways 2014	1.0	null
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.2738
narcolepsy	GAD Gene-Disease Associations	1.0	null
Perturb_10044_KD_EFTUD2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.59378
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855062
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.11844
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21877
Red blood cell traits	GWAS Catalog SNP-Phenotype Associations	1.0	0.881997
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4402
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938543
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14372
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-2.09994
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68077
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5241
Perturb_1424_KD_RUNX3_SRP159180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.7759
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8763
Perturb_5552_KO|KD_FBXO11|BAHD1_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.94689
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.407
Perturb_9865_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.09797
Perturb_9969_KD_WDR3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.86543
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78498
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932849
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1908
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1448
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6921
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.856814
GSE68156_3_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58291
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2778
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14372
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07298
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.65771
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2685
NCI-SNU-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01613
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
BCPAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94808
OCIMY7	CCLE Cell Line Gene CNV Profiles	1.0	1.34754
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863201
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10043_KD_EEF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.68868
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2731
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_9986_KD_U2AF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.90011
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8289
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.2943
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47009
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.976243
response to stimulus	GO Biological Process Annotations 2015	1.0	null
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932517
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.63887
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978941
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3911
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3489
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3597
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849826
AMO1	CCLE Cell Line Gene CNV Profiles	1.0	1.90622
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.37041
LP1	CCLE Cell Line Gene CNV Profiles	1.0	1.58948
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9271
Corpuscular Hemoglobin Concentration Mean	DisGeNET Gene-Phenotype Associations	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85669
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3835
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15044_KD_PTBP1_SRP124244	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LS-1034	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9235
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31642
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1835
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.2
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0247
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2172
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
HS944T	DepMap CRISPR Gene Dependency	1.0	2.69988
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5194
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.9008
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_9891_KD_HSPD1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.47749
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.42954
HUH6	DepMap CRISPR Gene Dependency	1.0	2.43993
GATA3	ENCODE Transcription Factor Targets	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39622
JM1	DepMap CRISPR Gene Dependency	1.0	2.14065
Perturb_10031_KD_MSI2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.43369
Perturb_9862_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.93826
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.69926
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0653
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6511
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892033
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.92366
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9424
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BHY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37499
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.6183
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20674
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04096
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52529
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1836
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43188
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03884
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76434
Perturb_9860_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.73229
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.12703
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.025
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.147291
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58186
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.301615
PECAPJ49	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14611
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Perturb_8383_KO_LSD1_DRP006351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.46749
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1708
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BHY	DepMap CRISPR Gene Dependency	1.0	3.39124
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975264
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10131_KD_GATA1_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.12391
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0637
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5043
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.76454
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.92
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7913
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47009
disease	GWASdb SNP-Disease Associations	1.0	0.033952
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.71984
JHH2	DepMap CRISPR Gene Dependency	1.0	2.14903
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Red blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48213
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.387201
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4385
C84	DepMap CRISPR Gene Dependency	1.0	3.36298
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3527
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36572
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863201
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932517
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79008
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1877
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.049879
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1885
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.55771
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0599
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857768
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84719
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50382
H3K36me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36168
SAP30	ENCODE Transcription Factor Targets	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.36313
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.54657
Perturb_9849_KO_PTPN2_SRP214323	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.85042
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7851
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6934
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.00664
NB1	CCLE Cell Line Gene CNV Profiles	1.0	1.53852
Perturb_14613_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.29771
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41545
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15415
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5438
SKMEL31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93865
Brain Lower Grade Glioma_LGG_TCGA-HT-7472-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1463	DepMap CRISPR Gene Dependency	1.0	2.05136
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22252
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.7213
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11784
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053945
Perturb_9864_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.45938
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2414
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72582
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71118
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5318
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9922
IGR39	DepMap CRISPR Gene Dependency	1.0	2.88074
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.3097
Mean Corpuscular Volume (Result)	DisGeNET Gene-Phenotype Associations	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47686
HOTHC	DepMap CRISPR Gene Dependency	1.0	2.17668
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84491
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.145
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852131
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00268
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23
Perturb_9939_KD_KIF1C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.8643
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9968_KD_UPF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.79255
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0949
OACP4C	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5279
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0237
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9935_KD_ATP5F1C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.62942
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4639-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.975988
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14823
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05769
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863201
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00385
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855062
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1121_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.88868
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SF295	DepMap CRISPR Gene Dependency	1.0	3.02953
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3248_OE_DDIT3_SRP335446	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.49547
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35003
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	1.0	1.63611
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10021_KD_PHF6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.92739
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ocellus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.748546
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9484
membrane	GO Cellular Component Annotations 2015	1.0	null
Perturb_10128_KD_eHDAC6_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.77732
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1254
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DOTC24510	DepMap CRISPR Gene Dependency	1.0	3.08411
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933204
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72582
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933661
SNU5	DepMap CRISPR Gene Dependency	1.0	2.48502
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_10005_KD_METAP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.13531
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSS	DepMap CRISPR Gene Dependency	1.0	2.6053
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6574
Perturb_10030_KD_EIF4G2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.26574
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5319
BICR16	DepMap CRISPR Gene Dependency	1.0	2.39072
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857768
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86468
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29576
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.921
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8416
OPM1	CCLE Cell Line Gene CNV Profiles	1.0	1.49357
Perturb_5735_KD_NAP1L3_SRP121475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.07011
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36372
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.68084
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1341
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.929777
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36372
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5654
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Perturb_11938_KO_SPI1_ERP119419	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.25816
Perturb_9975_KD_CKAP4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.96378
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7467
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0033
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
OCUM1	DepMap CRISPR Gene Dependency	1.0	2.80482
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX5	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Red blood cell traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.53979
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KALS1	DepMap CRISPR Gene Dependency	1.0	3.25868
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3611
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.790012
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9216
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MM370	DepMap CRISPR Gene Dependency	1.0	3.52056
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28783
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62633
Perturb_9944_KD_RBM15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.65608
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01723
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9097
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
Perturb_12017_KD_miR200b/a_SRP215447	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50154
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1518
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969915
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1744
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.12703
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
SF126	DepMap CRISPR Gene Dependency	1.0	2.29162
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08771
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8341
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_10001_KD_FMR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.09849
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
639V	DepMap CRISPR Gene Dependency	1.0	2.54739
Perturb_10045_KD_EIF3D_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.60794
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7288
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.45882
Perturb_10172_KO_TOX4_SRP300474	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.56446
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892033
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.91149
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0305
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_9856_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26954
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.35184
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75918
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.40625
pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.624927
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30786
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6875
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07298
biological regulation	GO Biological Process Annotations 2015	1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9777
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.89884
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6786
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.3329
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09181
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0526
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.828
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.69967
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9672
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5522
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07298
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930278
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847222
OV-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896023
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4976
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16352
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35059
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3717
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.68461
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1051
SNU407	CCLE Cell Line Gene CNV Profiles	1.0	1.39576
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05732
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9933_KD_AKAP8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.03921
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6896
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.65926
POLR2A	ENCODE Transcription Factor Targets	1.0	null
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298011
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.1761
Mean corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.82218
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.44943
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
HS683	DepMap CRISPR Gene Dependency	1.0	2.89175
Perturb_10036_KD_PUM2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.9666
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2152
Olfactory transduction	KEGG Pathways 2026	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5853
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90837
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.76454
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932849
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0254
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_9861_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.35317
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_10154_KD_ZRSR2_SRP265290	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.71763
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1828
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854689
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969453
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphocyte percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050779
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1296
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24087
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8249
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15549
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_1122_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.86888
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863201
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0596
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10053_KD_RRP9_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.42371
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2205
RBBP5	ENCODE Transcription Factor Targets	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5679