association	dataset	threshold value	standardized value
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.112
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6929
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3314
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06558
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5366
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.549
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7456
496100547_HIP_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84065
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.559
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0102
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2143
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2326
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9606
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1148
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1041
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7866
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4488
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9394
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8052
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.533
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8948
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2306
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4549
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0149
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4293
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9914
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8369
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0987
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.50671
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4695
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.766
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.452
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6454
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7243
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3169
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6658
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8921
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9177
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6841
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3245
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7268
496100314_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.52613
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0431
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.686
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6155
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7097
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.7101
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8962
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9704
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.53
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8849
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6395
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6383
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4297
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1395
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9703
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4384
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5283
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18742
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1444
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5393
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5622
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8273
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.087
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0976
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5141
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1725
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1386
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3515
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.1923
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7635
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7405
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6889
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1216
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.31
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8055
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7298
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8959
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5296
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6872
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.17
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6823
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6048
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76173
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1076
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.44
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4702
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9522
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100450_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82317
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6501
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8196
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5226
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3047
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.84031
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91506
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7046
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0898
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8529
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0747
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1993
Olfactory transduction	KEGG Pathways 2026	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2455
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10365
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8158
brain	GTEx Tissue Gene Expression Profiles	1.0	1.1669
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1021
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7651
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9153
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8312
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3082
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	2.14344
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9168
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32724
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.782
Diisocyanate-induced asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6809
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3761
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9208
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5757
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75946
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0528
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1263
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65929
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78209
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8862
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6165
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6283
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6345
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1723
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5623
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.49596
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.0632
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8094
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1305
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3634
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6546
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.356
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1949
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3493
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7502
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.7793
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0337
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3554
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9771
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.393
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8277
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19274
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1206
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8002
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0491
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6155
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9444
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2893
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8182
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7519
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25806
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0081
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8674
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0366
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.439
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4493
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3222
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6153
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.77
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2478
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1913