association	dataset	threshold value	standardized value
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2076
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1166
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80481
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21424
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01354
BRD-K74299234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15528
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.29525
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67662
BRD-K51753035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63001
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.325699
hsa-miR-765	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K75224334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10044
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9581
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9051
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WI-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
BRD-K72161690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84589
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3524
BRD-K09641927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67085
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07547
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3455
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9038
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.984
infection	GAD High Level Gene-Disease Associations	1.0	0.293278
hsa-miR-4506	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11869
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.290358
BRD-A05956997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00542
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08806
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3925
ONE58	DepMap CRISPR Gene Dependency	1.0	2.07145
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	0.949614
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84229
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26416
BRD-K15111910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05104
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HLF	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29404
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.15497
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47172
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826459
HS944T	DepMap CRISPR Gene Dependency	1.0	2.46002
BRD-K60848736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72367
NCIH28	CCLE Cell Line Gene Expression Profiles	1.0	2.12019
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13185
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.08877
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4684
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870737
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20629
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20456
indometacin-452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K79932545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31163
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.61098
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00525
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74735
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7S9-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.8467
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50915
BRD-K69375224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01795
TE10	CCLE Cell Line Gene Expression Profiles	1.0	1.61957
BRD-K32974773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16035
Placenta	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42659
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40833
Central sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14555
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6155
suxibuzone-2503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metrifonate-7287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2566
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL60	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.15607
non-small cell lung carcinoma	GWASdb SNP-Disease Associations	1.0	0.484105
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6758
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9756
BRD-K75626008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8924
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
nalidixic acid-7367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2486
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94758
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3047
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00313
BRD-K42478751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08656
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.04331
THP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0911
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.08575
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60177
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08973
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K48019220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88724
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31409
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975914
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FGFR3_KD_GSE41035_77_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36306
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956841
GM133	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.980028
UPCISCC026	DepMap CRISPR Gene Dependency	1.0	2.17836
SMC3	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.52423
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5012
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.19232
hsa-miR-2053	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
human immunodeficiency virus infectious disease	GWASdb SNP-Disease Associations	1.0	1.07307
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36612
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35513
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29352
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.40674
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8828
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9338
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.345983
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39572
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3112
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.63587
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.88266
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991646
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05367
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28084
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868534
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11884
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41839
BRD-K72531838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02658
boldine-4004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.63
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31316
CALU3	CCLE Cell Line Gene Expression Profiles	1.0	1.61553
BRD-K51654114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08679
SP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47811
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70108
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6386
S-117	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K16971439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46755
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7072
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.441
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.03502
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2012
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45047
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5158
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.63
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34449
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989963
BRD-K32132728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06717
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.46811
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
BRD-K87230984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03946
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19227
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57385
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100314_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.84438
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.15323
639-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47484
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74035
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.19554
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33612
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.997
BRD-K91773518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47375
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.17769
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09208
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	1.2516
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920558
BRD-K69097792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32679
BRD-K94540403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.063
BRD-K05645732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07508
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88015
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22911
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9372
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.8046
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24802
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889083
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73992
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77852
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20875
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18368
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.48451
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7151
BRD-K78697404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55552
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0402
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IST-SL1	GDSC Cell Line Gene Expression Profiles	1.0	1.82089
TRIM28_knockout_302_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.32712
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6901
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.54071
BRD-K81082554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76171
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.447
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
C84	DepMap CRISPR Gene Dependency	1.0	10.3754
Esophageal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.169
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K81644801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41677
BRD-K86961579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11668
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11827
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1208
signal transduction	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3145-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31736
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K78106941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46749
BRD-K57756744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.01789
FARAGE	DepMap CRISPR Gene Dependency	1.0	2.46694
BRD-K89447678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45456
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1347
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1917
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86065
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05575
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02936
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950243
BRD-K76492619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44746
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0222
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72034944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12109
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.982224
17711579-Figure1	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969308
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2802
Uric Acid Measurement (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K04635516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25323
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2961
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K10684867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35417
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33147
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985953
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89832379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01957
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6288
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20456
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05698
MDA-MB-453	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51439
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0743
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.996951
ioxaglic acid-3528	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0154
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69835
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32049
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19403
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28878
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7896
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88813
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.449
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0096
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18248
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19741
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.045
BRD-K64509231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7759
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09093
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.87845
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0408
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35623
IGR39	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.19243
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.41633
BRD-K10481024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72572
BRD-K98010525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32359
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K24070365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30055
arthritis	GWASdb SNP-Disease Associations	1.0	0.377678
SU8686	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5422
KM12	CCLE Cell Line Gene Expression Profiles	1.0	1.57725
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39248
enilconazole-6518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24831
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09064
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.16697
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
C32	DepMap CRISPR Gene Dependency	1.0	6.3167
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00093
WM2664	CCLE Cell Line Gene Expression Profiles	-1.0	-2.4674
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1061
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23871
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.169
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855814
BRD-K98164803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36978
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K48056188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43549
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.75886
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.64165
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02409
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	10.9819
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BPH1	DepMap CRISPR Gene Dependency	1.0	2.671
BRD-K62957665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39356
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98337
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32155
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889083
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5131
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.38021
fenspiride-2269	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60287661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3825
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52093
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.08204
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4256
BRD-K69505608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38731
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850156
A2780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01512
BRD-K43026564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78411
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5852
gentamicin-7237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K65729622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04816
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7779
BRD-K15380626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01067
BRD-K69922285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21212
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67155
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	1.15652
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63008
Arthritis, Psoriatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K75746738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0253
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40060703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06116
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4023
TP63_01_200	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.8864
BRD-K22694382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.523
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.069435
LAMA84	Achilles Cell Line Gene Essentiality Profiles	1.0	2.47578
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9682
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6135
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984694
BRD-K40452322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00919
CFPAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.41944
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908415
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07217
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99849
Body Mass Index Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54495109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04199
Esophageal cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
NCI-H596	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63101
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09922
CRCGN017_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00971
RAD21	ENCODE Transcription Factor Targets	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44622
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K03840522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78964
BRD-K04873321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16135
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06619
BRD-K62795540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15377
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81351
BRD-K66538269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00586
BRD-K78337983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63875
hsa-miR-19b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intelligence	DisGeNET Gene-Phenotype Associations	1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.63
GSE243491_1_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57315740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19329
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9249
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.969536
BRD-K71345532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62724
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27174
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93197
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10621121-40101_2023_341_MOESM1_ESM.docx-0-L3MBTL4_L3MBTL4	Rummagene Transcription Factor Associations 2026	1.0	null
Clove	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.363
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4953
CLDN18_KO_GSE48443_44_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K25876174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08573
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.15147
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00093
BRD-K30548577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53495
RPMI7951	DepMap CRISPR Gene Dependency	1.0	4.31523
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
MV411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39092
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
OCUM1	DepMap CRISPR Gene Dependency	1.0	2.32152
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46915
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.15385
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1294
BRD-K96663576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24626
BRD-K86002795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12346
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47279
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
Finding Of Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56965
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03105
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43184
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Pulmonary Function	DisGeNET Gene-Phenotype Associations	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889083
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20838
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88259
BRD-A35430844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02976
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73895
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K92431275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09577
BRD-K33217094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72887
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.276935
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K35122752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57769
BRD-K95457967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33864
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2064
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24622
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26682
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29843
SARS-CoV MA15_Day7-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.49358
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906967
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96536
BRD-K20071915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18492
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00301
santonin-4531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6245
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25222
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3862
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24551
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17379
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.5462
BRD-K12513721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69307
BRD-K22002407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04538
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
BRD-K51237617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56359
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889083
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847442
BRD-K12705251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64045
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OSRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.3992
BRD-K33380066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37906
immune system disease	GWASdb SNP-Disease Associations	1.0	0.076564
BRD-K33177501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49649
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7097
BRD-K41790019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18912
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.5715
BRD-K35208671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22255
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18620798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.477
serotonin-5633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COV504	DepMap CRISPR Gene Dependency	1.0	2.78796
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.07582
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04956
CRCGN015_MCF10A.TP53.M_24H:H12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05815
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.7637
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9467
tanespimycin-5958	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2911
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01816
EB1	CCLE Cell Line Gene Expression Profiles	1.0	1.82111
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEK_INHIBITION_GDS5029_279_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA1_DEPLETION_GDS3791_38_human_Hela	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Barrett Esophagus	DisGeNET Gene-Disease Associations	1.0	null
Benign epilepsy with centrotemporal spikes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63646
KYSE150	CCLE Cell Line Gene CNV Profiles	1.0	2.00728
LIVF001-028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37013
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8992
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74128
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30984
lung adenocarcinoma	GWASdb SNP-Disease Associations	1.0	1.1395
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15923
RKO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.15387
BRD-K27692586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25458
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3156
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57288
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.8002
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59807
BRD-K83180232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75423
SW620	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.10544
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.097792
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12874
hsa-miR-573	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.3165
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4798
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.18424
BRD-K61565464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06631
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989963
BRD-K50943704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6035
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46735
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87516
BRD-K35193502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2252
BRD-K39824708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66052
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965198
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03105
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Multiple synapse bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
BRD-K68118416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03316
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUSA	DepMap CRISPR Gene Dependency	1.0	2.85827
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.02047
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41511
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6877
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.92111
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BRD-K27723822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09455
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79104
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923454
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.072128
adipiodone-5085	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JVM-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69603
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.6271
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06448
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49355
Dorsal claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00595
CHLA90	DepMap CRISPR Gene Dependency	1.0	5.24693
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90477
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1541
DLD1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.89467
disease	GWASdb SNP-Disease Associations	1.0	0.053552
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49754
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.05495
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41055
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17312
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5411
HCT15	BioGPS Cell Line Gene Expression Profiles	1.0	0.837616
hsa-miR-676	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887978
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04439
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34952
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	2.57661
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87424
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6763
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
253J	CCLE Cell Line Gene Expression Profiles	1.0	1.56253
DOTC24510	DepMap CRISPR Gene Dependency	1.0	2.34683
PLB985	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.80437
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.851361
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.041059
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.968
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.295
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.081796
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8864
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.71983
BRD-K15690866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13062
NCI-H1792	GDSC Cell Line Gene Expression Profiles	-1.0	-1.99882
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4316
BRD-K68383485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08803
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	1.09604
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87735
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31337
EW-22	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87024
U178	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.33311
BRD-K98535230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72568
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	2.95203
Signal Transduction	Reactome Pathways 2014	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39848
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26364
Corpuscular Hemoglobin Concentration Mean	DisGeNET Gene-Phenotype Associations	1.0	null
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.77971
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Glomerular Filtration Rate	DisGeNET Gene-Phenotype Associations	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2468
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19709
BRD-K34595206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60879
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889817
ZR75_1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44762
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01239
hsa-miR-922	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82538
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78939
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0683
BRD-K72463020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21679
G402	DepMap CRISPR Gene Dependency	1.0	2.23841
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.158
FOXP2	ChEA Transcription Factor Targets	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41984
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.21885
eticlopride-4634	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918394
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.8012
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98667932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20004
SKUT1	DepMap CRISPR Gene Dependency	1.0	3.55943
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0501
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7605
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5181
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.088026
A704	CCLE Cell Line Gene Expression Profiles	1.0	1.57513
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.251187
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985953
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	2.05826
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881556
PMC5865663-oncotarget-09-14193-s002.docx-0-Supplementary_Table_S2_Somatic_mutation_Genes_which_are_high_frequency_in_TP53_signature_MT_TCGA_data_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77697725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05248
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25057
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72339
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
labetalol-3167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.63
BRD-K70945620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01841
BRD-K40694355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25748
SOX2_Deficiency_GDS4853_321_human_AZ-521 gastric cancer (GC) cell line - 18 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2171	GDSC Cell Line Gene Expression Profiles	1.0	1.90411
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05197
BRD-K34620971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16251
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17138
BRD-K28795679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07352
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3668
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2843
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825001
BRD-K66802550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44887
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.3646
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08359
hsa-miR-4777-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	2.03928
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23389
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15785
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889083
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931036
BRD-K29908513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30482
BRD-K75620843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76759
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5796
cell part	GO Cellular Component Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57565
SW579	DepMap CRISPR Gene Dependency	1.0	3.20736
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54088
BRD-K05127596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59086
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1047
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849559
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.098105
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8738
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.66
COLO-679	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45369
BRD-K94685656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46149
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86696
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23615
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03017
CRCGN011_HEPG2_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00895
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.304118
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855814
BRD-K12017137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53912
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27237
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0425
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9821
BRD-K10655148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18269
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.03915
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9015
BRD-K47078472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25974
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9357
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34389
BRD-K88539660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61822
estrone-6647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0017
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4948
BRD-K38481376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04212
dr9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54026
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18725
BRD-K59185421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13721
BRD-K38131403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33092
BRD-K81189877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02135
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49402
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3214
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33972
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	2.60401
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.12761
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06397
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83254798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57208
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10096
Familial combined hyperlipidaemia_Blood monocyte_GSE11393	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.32447
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4985
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24321
NCI-H460	GDSC Cell Line Gene Expression Profiles	-1.0	-2.84559
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	1.31031
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40459
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59237
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02314
BRD-K77221872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01029
BRD-K79213964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08761
hsa-miR-3679-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33379
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.42733
BRD-K32240435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34193
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24967
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52185
CP50-MEL-B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K31503053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06405
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84023
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39439
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8492
bisoprolol-6748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3776
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974317
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HTK	CCLE Cell Line Gene Expression Profiles	-1.0	-2.45677
BRD-K75842461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25443
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8144
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
BRD-K22139757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08969
immune	GAD High Level Gene-Disease Associations	1.0	0.298214
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acenocoumarol-2240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8848
COLO849	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46287
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844662
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39063
BRD-K28700379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03239
BRD-K63579322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16875
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.5736
BRD-K57017252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2494
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.59187
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73494
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38254
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.57417
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12641
BRD-K11667893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30642
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00302
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22827
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84432
hsa-miR-374b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4903
hsa-miR-1185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hsa-miR-4511	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
DBTRG05MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.53656
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.866292
BRD-K68160857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56873
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31065
BRD-K72765192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22311
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05885
BRD-K83567669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21967
BRD-K17549032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21483
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3094
BRD-K26526202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69962
CLDN18_KO_GDS4961_28_mouse_whole lung tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K25149224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45637
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.174309
AGS	GDSC Cell Line Gene Expression Profiles	1.0	1.43653
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25855
UACC-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.9146
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.55295
BRD-K58932103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51856
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03193
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889817
BRD-K43798660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75531
BRD-K64183190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28595
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5638
ES4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IPC298	DepMap CRISPR Gene Dependency	1.0	3.50801
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2349
tocainide-4256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77480803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26809
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4372
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53433
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12869
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09108485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54914
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24433
BRD-K00767817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14205
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919938
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.2962
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4848
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8799
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96577
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5965
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.890578
HEC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
NCIH1666	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82448
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27957
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7592-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.13685
U87MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01134
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38371
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65876
BRD-K76173551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18955
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31216
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.17156
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61416
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.21454
BRD-K77203880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30893
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8625
CRCGN017_MCF10A.WT.HP_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00621
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7245
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	1.14772
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7733
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86503
BRD-K64567083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08721
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855814
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838166
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26556
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2058
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75938
estradiol-6718	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22586
hsa-miR-1276	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3653
MCAS	DepMap CRISPR Gene Dependency	1.0	2.44882
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.44516
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K84145110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3615
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AX-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22907310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3185
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K63500288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51509
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_15603_KO_CypD_SRP298064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5726
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2158
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.03978
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YD38	CCLE Cell Line Gene Expression Profiles	1.0	1.39365
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K37763427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31553
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2605
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.27213
BRD-K12633506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30048
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.087736
BRD-K87967738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3072
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10516
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06789
PBX1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4536	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11719
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.36621
BRD-K96389533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17142
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.33245
BRD-K64663625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38409
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5338
BRD-K65959331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31891
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23135
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.8344
BRD-K47804666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00126
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23927
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0276
A204	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.15224
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hiv infections; [x]human immunodeficiency virus disease	GAD Gene-Disease Associations	1.0	null
BRD-K12841150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09286
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95187
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
cellular_component	GO Cellular Component Annotations 2015	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84229
BRD-K16207499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.077
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12474
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
PTHrP_KD_GDS1664_438_human_MDA-MB-231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH2170	DepMap CRISPR Gene Dependency	1.0	2.31517
Chronic obstructive pulmonary disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16297
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1089
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.41073
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.0025
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2339
BRD-K32451879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13633
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.41306
Asthma	DisGeNET Gene-Disease Associations	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
Fish- and plant-related diet	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25429
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24577
BRD-K78847404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96968
hsa-miR-660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3807
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46878
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67773
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13066
BRD-K48541282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05327
BRD-K69668461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48103
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.6908
Forced Expiratory Volume Function	DisGeNET Gene-Phenotype Associations	1.0	null
Barrett's esophagus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.169
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80917
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27519
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15769
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.470127
CRCGN012_HEPG2_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15129
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26074
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.59317
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52852
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.0707
BRD-K47618355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37888
BRD-K67525206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12588
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04313
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81911
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07572
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3541
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139966_4_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.41549
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29367
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC1A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92756
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19833
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34974
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32479
multiple sclerosis	GAD Gene-Disease Associations	1.0	null
BRD-K65438558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90721
BRD-K08971733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44173
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.723
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15217
ethosuximide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13649
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.42287
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03193
Sensory Perception	Reactome Pathways 2024	1.0	null
Periodic limb movement disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
CAKI-1	GDSC Cell Line Gene Expression Profiles	1.0	2.53602
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.17197
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.03671
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889083
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4538
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50675
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906967
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5442-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139948_3_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.20936
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1298
EWSR1_KD_GDS4962_465_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K70751829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15162
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84229
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09623
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6881
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
pravadoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12543
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46361
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.65841
BRD-K87781745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06108
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96664
hsa-miR-4443	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
immunodeficiency	GWASdb SNP-Phenotype Associations	1.0	1.09148
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8214
Multiple Sclerosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K61934967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36975
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18072
NCIN87	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37696
BRD-K76431854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97994
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.49091
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83681
hsa-miR-3611	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
rotenone-5915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77181307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5463
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21634
receptor activity	GO Molecular Function Annotations 2015	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98944
BRD-K63754039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0462
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5469
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5649
BRD-K74794014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88958
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9582
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0742
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16414
GCIY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K91241684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61559
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.301385
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86687
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33221810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21884
SP3_01_290	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.67015
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.14593
TC32	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1013
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73485
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0551
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K45495870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0451
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6629
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87487
Prostate adenocarcinoma_PRAD_TCGA-V1-A8X3-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39345
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33719
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18377
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42815
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02472
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37904
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.51549
PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0467
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51517
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18377
BRD-K69515345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7416
hsa-miR-3074-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K60430317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94611
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.18385
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66381
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81896
BRD-K50367303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09661
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6699
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.7173
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05314
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.186
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0726
BRD-K05261220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39289
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
BRD-K69482343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08241
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2836
Glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24446
HMC18	CCLE Cell Line Gene Expression Profiles	1.0	1.49775
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36023
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15953
BRD-K79437066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39473
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	85.6
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75206
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.36181
LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DKMG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.64009
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.70514
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923676
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZW-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76878
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12574
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09941
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.7538
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34768
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33371
MCC13	DepMap CRISPR Gene Dependency	1.0	2.48088
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28267
Respiratory Function Tests	DisGeNET Gene-Phenotype Associations	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7651
hsa-miR-3682-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13181
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8663
PECAPJ41CLONED2	CCLE Cell Line Gene Expression Profiles	1.0	1.47815
BCPAP	DepMap CRISPR Gene Dependency	1.0	2.14362
KOSC-2	GDSC Cell Line Gene Expression Profiles	1.0	1.57211
WM115	DepMap CRISPR Gene Dependency	1.0	2.3058
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894708
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970814
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08007
RDES	CCLE Cell Line Gene Expression Profiles	1.0	1.52298
hsa-miR-19a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.602
BRD-K89624539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46251
BRD-K63436783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14592
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8878
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2991
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20345
BRD-K46549154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01986
BRD-K90660470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79318
BRD-K76892938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37957
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9931
GSE139948_3_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3233
BRD-K41410736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72976
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1669
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7623
hsa-miR-370	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87049
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.98441
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957807
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24577
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05741
BRD-K91945291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16866
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42265
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10739
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00881
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15332
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7086-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961352
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868214
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960568
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957636
SNU1327	DepMap CRISPR Gene Dependency	1.0	3.32892
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
BRD-K22599787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26108
Olfactory transduction	KEGG Pathways 2026	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0408
NCIH661	DepMap CRISPR Gene Dependency	1.0	2.05442
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.70115
BRD-K11474067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03088
GSE194358,GSE194361_0_v_1_kdm5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K29519734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20039
COGAR359	DepMap CRISPR Gene Dependency	1.0	2.18789
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29381
HCC1143	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13551
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.64877
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70286
thioproperazine-2236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64027
BRD-K69942587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77657
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5021
BRD-K43909206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47651
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81469
lung cancer	GWASdb SNP-Disease Associations	1.0	1.30364
18722011-SuppTable2l	GeneSigDB Published Gene Signatures	1.0	null
BRD-K86872145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29937
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18756
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981773
biperiden-5644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K22743786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53088
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0108
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
Lupus Erythematosus, Systemic	dbGAP Gene-Trait Associations	1.0	0.774296
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.26835
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.63
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K83619973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4528
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25408
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40210962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5032
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.12422
interleukin-4 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1495
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58014
ST486	CCLE Cell Line Gene Expression Profiles	1.0	2.33524
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.066661
BRD-K04731905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29692
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.1387
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	2.22627
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.475
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2727
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8809
BRD-K49830011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1371
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4016
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.41423
BRD-K46588240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23814
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5317
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2239
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22911
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7326
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
flunisolide-3747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30549
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.41117
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41984
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9174
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41968
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3684
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887978
Sarcoidosis	DisGeNET Gene-Disease Associations	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.63
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
aztreonam-2282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AGS	DepMap CRISPR Gene Dependency	1.0	2.90688
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	1.91871
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.8163
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K77832645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49033
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.765
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18756
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58998
BRD-K66907139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22156
BRD-K78015598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02596
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9773
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79982586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34767
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3717
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2645
Anxiety disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.403
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2823
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9935
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42975
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855814
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K73213708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33881
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45734366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38896
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0163
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42471
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56218
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.84277
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24446
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5102
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23038
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43842
tanespimycin-450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15419
HT-1376	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7227
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.51365
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43087
BRD-K75074041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0448
BRD-K17180926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69905
ketoconazole-4624	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46532
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27455
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K48501991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1915
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26082
BRD-K08205503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.82637
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04109
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855814
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10009
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acquired immunodeficiency syndrome	GWASdb SNP-Disease Associations	1.0	1.2461
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	1.0	2.53212
CH157MN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76428
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49879
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23076
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4438
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5181
all	GWASdb SNP-Phenotype Associations	1.0	0.047026
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Hemoglobin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.7699
BRD-K39921641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12315
Platelet alpha granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
clobutinol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32278
cancer	GWASdb SNP-Disease Associations	1.0	0.09009
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41511
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18306
biological regulation	GO Biological Process Annotations 2015	1.0	null
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3755
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8998
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K66016089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23383
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0915
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201042_6_v_0_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919018
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	1.15652
Lung Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-4715-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10234
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6191
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.3985
hsa-miR-3685	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
calcium pantothenate-4189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7742
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinopathy in non-diabetics	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.078255
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.98148
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838912
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.04325
altizide-2527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nisoxetine-6496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5967331-41467_2018_4384_MOESM4_ESM.xlsx-Sup_data1_with_CCF_txt-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65891102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39275
BRD-K30198800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48335
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Asthma and major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7915
JHH2	DepMap CRISPR Gene Dependency	1.0	5.21775
BRD-K76154866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41863
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0461
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_8400_KD_Srrm2_SRP195765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.0518
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9681
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75832
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3558
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.168
Daytime sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.17765
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83874
BRD-K35702939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38382
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K34136030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12127
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1143
HCC827GR5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15396
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74439
BRD-K60429174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7141
prednisolone-5101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5295
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.359234
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.21745
HOXC6_01_333	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.9208
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3319
BRD-K42576592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86182
altretamine-4627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9178
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.01569
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47089
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4036
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5452
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.77265
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0855
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.975666
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42815
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5648
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6739
BRD-K93894185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52113
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894128
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.042
BRD-A02501536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6573
cobalt chloride-383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0218
BRD-K86953192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1138
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K37696710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54777
BRD-K30625175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00443
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21767
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.7432
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.22723
BRD-K62000282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44129
BRD-K85359245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0475
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	1.35922
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MM370	DepMap CRISPR Gene Dependency	1.0	2.43535
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.93907
BRD-K91795767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02106
Signaling by GPCR	Reactome Pathways 2014	1.0	null
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	1.0	1.37137
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49475
LY-294002-401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2071
Social communication problems	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-890	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
strychnine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19681
HT29	Achilles Cell Line Gene Essentiality Profiles	1.0	1.50847
Prestwick-1080-3796	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25012
BRD-K76966915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0399
Carbohydrate metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
BRD-K20347026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21935
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1485
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894708
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.79871
doxorubicin-5671	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870306
hsa-miR-4474-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K66838288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81407
M040416	DepMap CRISPR Gene Dependency	1.0	12.6888
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33116
BRD-K86937728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36043
bone disease	GWASdb SNP-Disease Associations	1.0	0.196115
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5526
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.34589
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69438
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4122
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1603
BRD-K02630367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37764
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	1.17942
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99137
OVCAR3	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.858468
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.156852
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4672	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.91586
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0587
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2564
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.859
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Esophagus adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
NCIH1299	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03138
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47267
lung carcinoma	GWASdb SNP-Disease Associations	1.0	0.429581
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1444
SF126	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22549
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84229
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00775
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	1.38195
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9407
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.258
post-traumatic stress disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.403
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7344
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866969
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2708
BRD-K89949395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18335
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01148
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.92699
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.63
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94862
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	0.998548
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.855283
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02185
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871507
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943476
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.210277
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.05502
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41313
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6399
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16243
BRD-K01973494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74414
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04378
BRD-K70856965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66298
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0618
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6979
K562	CCLE Cell Line Gene Expression Profiles	1.0	1.59031
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53107
BRD-K69238239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36865
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0566
BRD-K95651150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18753
BRD-K71169857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5774
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58180017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54438
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93245
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2924
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00313
SNU1196	DepMap CRISPR Gene Dependency	1.0	2.69092
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2934
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15686
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899269
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09672
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84229
hsa-miR-3616-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.07792
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.871
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.91041
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894319
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92792
BRD-K73858940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10216
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31215
membrane	GO Cellular Component Annotations 2015	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30903
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01618
membrane part	GO Cellular Component Annotations 2015	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
BRD-K62072978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59647
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913185
SJSA1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.01373
ciclosporin-261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26074
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.47449
BRD-K16605233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23958
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
tanespimycin-381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8628
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9455
NCI-H2030	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K64665523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55479
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14129
BRD-K66973998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07776
BRD-K80150641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52744
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0795
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.651
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.139108
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33913
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	1.14151
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9259
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.210277
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906488
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXP1_01_208	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32029
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16491
imatinib-366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.41
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889083
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.73548
BRD-K62152527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20893
BRD-K34433706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17179
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K42506600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92315
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4887
BRD-K22718400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78809
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8472
tyloxapol-5672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82185
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46337
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.96
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24454
Pulmonary Function (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03994
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18069
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15365
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55668
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74439
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14132
NB13	GDSC Cell Line Gene Expression Profiles	-1.0	-2.20993
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69826976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14022
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.17899
hsa-miR-320e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63231
BRD-K98586629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9889
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.53875
hsa-miR-4260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.757
hsa-miR-4272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05285
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60177
BRD-K96807219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44283
VMRCRCW	DepMap CRISPR Gene Dependency	1.0	5.94061
BRD-K08715020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10893
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5052
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
HCC515	DepMap CRISPR Gene Dependency	1.0	2.20444
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6588
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.114349
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82725
viral infectious disease	GWASdb SNP-Disease Associations	1.0	0.410796
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2671
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910307
BRD-K14925361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35532
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3168
Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.0
myricetin-4090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27833
BRD-K51017127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29459
Esophageal carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.104