association	dataset	threshold value	standardized value
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91444
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55103
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982263
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05698
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9402
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842617
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00913
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
HCC1937	DepMap CRISPR Gene Dependency	1.0	3.78299
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24665
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0872
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25409
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1238
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4994
UMUC10	DepMap CRISPR Gene Dependency	1.0	2.24258
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.39078
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05162
H3K9me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.773
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.442
496100306_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37877
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27156
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF767	CCLE Cell Line Gene CNV Profiles	1.0	1.40297
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909852
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood clot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.974583
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8948
HHV-8_72Hour_18587055_GSE6489	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.02778
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4054
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.96332
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.64507
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.599994
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30063
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47015
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.828992
signal transduction	GO Biological Process Annotations 2015	1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.8842
cellular_component	GO Cellular Component Annotations 2015	1.0	null
13c4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.664
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	3.41352
Pancreatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	2.212
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7853
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41124
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8344
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.671928
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12029
Coronary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85565
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5848
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07315
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95716
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04953
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
LAN2	DepMap CRISPR Gene Dependency	1.0	3.71436
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905459
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12772
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3737
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0525
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71298
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1758
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.877482
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55548
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8701
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90066
MDAMB231	DepMap CRISPR Gene Dependency	1.0	2.68923
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951184
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42145
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874793
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05133
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35737
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829327
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49977
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7556
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3347
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.01942
BV173	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96329
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963458
FADU	DepMap CRISPR Gene Dependency	1.0	2.95124
congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.460506
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204263
PANC0213	CCLE Cell Line Gene CNV Profiles	1.0	1.38841
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03454
OVMANA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72498
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58308
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885685
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881866
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842617
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28452
TCF4	ChEA Transcription Factor Targets	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8235
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915837
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043312
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3392
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7836-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.18558
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44107
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847783
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.92613
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7364
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNCAPCLONEFGC	DepMap CRISPR Gene Dependency	1.0	3.12267
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27156
JHOS2	DepMap CRISPR Gene Dependency	1.0	2.8911
response to stimulus	GO Biological Process Annotations 2015	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980246
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82558
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8892
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14445
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.947742
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.316456
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7431
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2808
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8472
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56578
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894832
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14199
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041157
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.888146
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93041
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869402
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39232
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66764
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040169
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79423
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039601
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039811
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97588
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8918
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843753
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7546
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853897
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1587
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-2.69277
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.848
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21617
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06067
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.46864
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891897
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4021
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6082
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28469
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050855
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.019
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2461
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967317
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03368
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053318
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849996
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67471
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.78641
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3383
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05547
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921922
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62098
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WQ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.253831
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842529
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63779
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03459
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95846
SKRC31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54491
ME-180	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.75076
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915837
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33673
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
FOXO3_01_267	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.73087
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8164-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0116
SF126	DepMap CRISPR Gene Dependency	1.0	2.87749
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8075
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61981
TFK1	DepMap CRISPR Gene Dependency	1.0	2.40665
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4913
GNE myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3413
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.26081
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.971142
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9256
L428	DepMap CRISPR Gene Dependency	1.0	3.44965
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40314
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842617
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11492
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.28
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.80786
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00913
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.04384
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45207
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93546
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22749
CCFSTTG1	DepMap CRISPR Gene Dependency	1.0	2.27117
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.184863
769P	DepMap CRISPR Gene Dependency	1.0	3.31823
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050855
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14199
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13702
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01826
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69759
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095324
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06639
PMC3878729-1471-2148-13-273-S1.xls-Gene_List-Zfp9_ZNF25	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42689
rheumatic fever	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04209
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949101
ISTMES2	DepMap CRISPR Gene Dependency	1.0	2.95693
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881387
OE19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REH	DepMap CRISPR Gene Dependency	1.0	2.14786
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14419
Kawasaki disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95597
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2859
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.62279
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04689
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03365
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26723
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44348
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.8111
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.826814
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862665
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856468
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94897
PMC3348545-NIHMS263168-supplement-3.pdf-176-ZNF510_ZNF510	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0427
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8303
PMC12116329-CTM2-15-e70302-s002.xlsx-Suppl_Table_1-Supplemental_Table_1_Top_upregulated_and_downregulated_genes_following_MSC_cytotherapy_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03628
GATA3	ENCODE Transcription Factor Targets	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19384
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2337
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84435
TRIM28	ChEA Transcription Factor Targets	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06848
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45207
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.709
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.28084
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904482
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940954
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.33622
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.941986
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8156
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891897
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5508
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CL-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00913
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50564
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5227
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4862-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEL290	DepMap CRISPR Gene Dependency	1.0	2.1724
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.395
Prostate adenocarcinoma_PRAD_TCGA-G9-6361-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5625
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28761
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854855
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1744
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5564
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7549
RERFLCAD1	DepMap CRISPR Gene Dependency	1.0	2.02079
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1641
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2805
COLO678	DepMap CRISPR Gene Dependency	1.0	2.57761
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0142
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46074
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78489
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956057
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3392
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-497-ZNF295_ZBTB21	Rummagene Transcription Factor Associations 2026	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41363
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4823
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.03813
KMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60807
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24196
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844282
COLO679	DepMap CRISPR Gene Dependency	1.0	3.88312
core of nucleus accumbens	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897435
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873566
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47745
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3249
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6077
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.087
Choreaacanthocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91888
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.55264
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26193
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.17116
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.762916
NFIA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957644
NCIH1793	CCLE Cell Line Gene CNV Profiles	1.0	1.45578
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44178
UBLC1	DepMap CRISPR Gene Dependency	1.0	2.1936
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55191
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6099
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85565
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
H3K9me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ICC9	DepMap CRISPR Gene Dependency	1.0	3.00868
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29373
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1212
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5933
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5192-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06025
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10437
HCAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.467
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44348
CLASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58445
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33886
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891118
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
HCC366	DepMap CRISPR Gene Dependency	1.0	3.43813
PMC3708595-NIHMS474972-supplement-1.pdf-8-MYB_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.949759
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5645
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861305
TE14	CCLE Cell Line Gene CNV Profiles	1.0	3.01694
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31565
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35757
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
C32	DepMap CRISPR Gene Dependency	1.0	2.09882
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051447
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835949
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845333
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4983
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.39773
SAP30	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.39036
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62106
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48621
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96713
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.811032
SLR23	DepMap CRISPR Gene Dependency	1.0	2.73765
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904031
MEK_INHIBITION_GDS5029_279_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.12823
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CL-40	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.02018
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D341Med	DepMap CRISPR Gene Dependency	1.0	2.36316
Cogan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	4.18122
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22749
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8229
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01556
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6904
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27156
SNU620	CCLE Cell Line Gene CNV Profiles	1.0	1.43194
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864093
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8319
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	2.56449
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2819
STAT3	ENCODE Transcription Factor Targets	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.28084
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.35692
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8455
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.93381
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63402
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19492
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21793
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8407
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16229
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042335
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06504
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.69149
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0051
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88048
Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC549	DepMap CRISPR Gene Dependency	1.0	3.06411
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.40462
HCC2429	DepMap CRISPR Gene Dependency	1.0	2.65506
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RH18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43766
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20437
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.611
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.941623
MAP2K1_knockdown_134_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44896
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5265
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0503
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5397
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869872
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946909
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-11A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6767-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7584
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7744
DMS53	DepMap CRISPR Gene Dependency	1.0	3.57562
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52645
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980246
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7227
HCC202	DepMap CRISPR Gene Dependency	1.0	2.4183
SKMEL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35287
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.1936
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54365
pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280082
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1915	DepMap CRISPR Gene Dependency	1.0	6.15514
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902534
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
BICR16	CCLE Cell Line Gene CNV Profiles	1.0	1.48447
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5619
59M	CCLE Cell Line Gene CNV Profiles	1.0	2.17149
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21879
NCIH2030	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5433
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3887
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81637
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0504
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90904
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27156
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6049
C10	DepMap CRISPR Gene Dependency	1.0	3.09041
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0608
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40952
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27156
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90178
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPM2	DepMap CRISPR Gene Dependency	1.0	3.01203
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0018
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81389
A253	DepMap CRISPR Gene Dependency	1.0	2.84342
BC3C	CCLE Cell Line Gene CNV Profiles	1.0	1.50508
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02392
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.765
lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01456
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6806
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06018
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03633
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853897
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36837
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22491
occipito-temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.962949
SNCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33172
ZFX_KD_GSE43021_130_human_NOMO1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.385
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3352-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDQ-P1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.79577
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33882
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.565666
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06957
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053819
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30238
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5085
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07318
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.38025
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.005
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5631
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10437
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980246
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79046
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95846
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1569
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911815
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050968
EM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65725
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26783
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11296
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21549
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2659
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17199
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.877911
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.99054
SK-N-DZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.238
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
FBXL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83599
CTCF	ENCODE Transcription Factor Targets	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853897
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27187
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12116
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6054
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05429
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1827
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893552
KNS42	CCLE Cell Line Gene CNV Profiles	1.0	1.58221
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24412
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46336
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927871
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02529
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.972
Fanconi anaemia nuclear complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2081
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.618478
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06279
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03215
LU65	DepMap CRISPR Gene Dependency	1.0	5.6442
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06848
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.85697
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05906
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	4.58492
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894626
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985773
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28452
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3594
cell part	GO Cellular Component Annotations 2015	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8669
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8381
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0354
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78362
496100583_PCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1961
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50431
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GU-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47636
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909282
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00229
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60895
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6039
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35788
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05944
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6026
MM127	DepMap CRISPR Gene Dependency	1.0	2.07162
APH1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46543
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24231
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.40741
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS27	DepMap CRISPR Gene Dependency	1.0	4.04265
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8848
SNU349	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34344
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL989 (PDS5A)	NURSA Protein Complexes	1.0	null
Oblique facial clefting 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.326
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6371
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34195
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00913
Brain Lower Grade Glioma_LGG_TCGA-CS-5397-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26402
SKGT2	DepMap CRISPR Gene Dependency	1.0	4.73143
postcentral gyrus, left, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04065
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21225
SNU489	CCLE Cell Line Gene CNV Profiles	1.0	1.35996
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59402
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4512
molecular_function	GO Molecular Function Annotations 2015	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.292
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.79143
left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.974583
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40226
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02395
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04138
CASKI	DepMap CRISPR Gene Dependency	1.0	2.56104
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4964
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7298-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03459
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054535
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.02266
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4352
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3178
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860078
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832517
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.06057
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.513
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PM-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.940978
MERO25	DepMap CRISPR Gene Dependency	1.0	3.19553
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.832998
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
EZH2	ENCODE Transcription Factor Targets	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08751
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52677
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11191
SKCO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34205
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31321
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7593
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.43516
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436438
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925087
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35257
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.18621
DAOY	CCLE Cell Line Gene CNV Profiles	1.0	1.48997
G361	CCLE Cell Line Gene CNV Profiles	1.0	1.40575
SKES1	CCLE Cell Line Gene CNV Profiles	1.0	2.15435
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.299
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851405
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.5557
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944838
MCC142	DepMap CRISPR Gene Dependency	1.0	2.10271
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87887
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0329
Teebi hypertelorism syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75111
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1834
WM3772F	DepMap CRISPR Gene Dependency	1.0	3.90077
CDK7_knockdown_138_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.57021
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26141
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039921
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26007
Signaling by GPCR	Reactome Pathways 2014	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43589
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942162
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
MSTO211H	DepMap CRISPR Gene Dependency	1.0	2.8472
Neuroacanthocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05569
Supraspliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.107
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06848
postcentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.833081
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF295	DepMap CRISPR Gene Dependency	1.0	2.19478
EOL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10927
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35517
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5975
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03498
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827826
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.977664
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49801
ICC8	DepMap CRISPR Gene Dependency	1.0	3.40801
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10383
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.107
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49689
biological regulation	GO Biological Process Annotations 2015	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28452
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5007-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49592
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.40178
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05944
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14199
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999489
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	2.13261
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Y79	DepMap CRISPR Gene Dependency	1.0	2.5922
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79493
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13964
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70756
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891118
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLVL	DepMap CRISPR Gene Dependency	1.0	3.96968
Olfactory transduction	KEGG Pathways 2026	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902333
biological_process	GO Biological Process Annotations 2015	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.57752
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5423
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0771
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07614
Teebi hypertelorism syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.075
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15162
atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.758673
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19917