association	dataset	threshold value	standardized value
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.82944
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3373
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6868
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3404
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.09577
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8914
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5547
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4488
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4991
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1128
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3216
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4615
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4296
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.8969
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3405
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9263
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.798
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3651
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3192
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.879
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0682
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3622
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7258
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8179
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6865
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1221
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5286
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5569
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6789
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8726
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2874
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1145
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2402
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6842
496100661_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.4045
496100638_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46795
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2338
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5113
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.641
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8396
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1883
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4286
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.829
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8203
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3826
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2475
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2792
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7112
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4104
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0644
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5108
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7743
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6407
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.90513
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0672
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.349
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9474
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7252
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4932
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.263
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5395
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1646
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7202
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4885
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3362
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2622
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0449
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8246
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6368
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2603
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2857
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3397
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9605
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4482
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE84678,GSE93902_3_v_0_bcl11b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4484
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1188
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.59264
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4066
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1299
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0315
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0781
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7601
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9636
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6792
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28777
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1663
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2265
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2435
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9176
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2236
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8442
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6742
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9953
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8423
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8281
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4919
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8558
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7747
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6783
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2385
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7513
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9303
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5532
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9709
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8891
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7405
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.702
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0156
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8323
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6782
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.75862
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8339
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0893
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.99768
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5556
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6076
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0325
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2345
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8698
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0088
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5278
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5391
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7654
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4656
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9911
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6799
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3093
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7332
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2654
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2332
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5161
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5312
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.446
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3191
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0638
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8757
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5054
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5077
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3909
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2251
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.22482
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83297
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5049
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0595
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3178
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6929
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5786
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2212
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6179
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6057
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6504
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.36873
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3235
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2561
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4627
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4831
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9983
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7037
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.247
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0702
496100667_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8618
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7473
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2316
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8211
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5111