association	dataset	threshold value	standardized value
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38419
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42485
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1585
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49761
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14931
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86636
CRIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30102
Prostate adenocarcinoma_PRAD_TCGA-VP-A878-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25151
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91011
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850381
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40928
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-0.898225
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57161
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89636
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2568
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.388
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854883
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53963
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07869
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940977
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86265
OCI-LY7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.1389
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12685
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30798
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E7-01A-31R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.25
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40121
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07713
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99347
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59115
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48824
signal transduction	GO Biological Process Annotations 2015	1.0	null
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51445
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47877
EZH2	ENCODE Transcription Factor Targets	1.0	null
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18577
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11645
MEL270	DepMap CRISPR Gene Dependency	1.0	3.40392
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-2.83306
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64829
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.497
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14031
cellular_component	GO Cellular Component Annotations 2015	1.0	null
ERG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23452
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77652
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55636
G361	CCLE Cell Line Gene CNV Profiles	1.0	1.38419
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17048
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56171
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72596
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34438
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48651
RFX5	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19958
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92992
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3763
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.34145
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9263
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3322-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15643
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902849
biological regulation	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3265
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886965
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88962
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36879
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47176
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31616
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21551
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18821
RIGI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08943
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847973
Signal Transduction	Reactome Pathways 2014	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34834
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42907
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52842
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00586
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05014
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86252
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0145
CAS1	DepMap CRISPR Gene Dependency	1.0	2.99198
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59904
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74072
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68891
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7339
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17143
PHF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38712
Olfactory transduction	KEGG Pathways 2026	1.0	null
ECC4	DepMap CRISPR Gene Dependency	1.0	2.12988
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16408
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1105
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.90269
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31329
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22749
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1363
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36369
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23775
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74371
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7588
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
HO1U1	DepMap CRISPR Gene Dependency	1.0	3.51096
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89974
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92993
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.48713
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77019
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55863
FOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82811
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
VARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70785
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.812
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95344
CEPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12015
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63911
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4972-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68107
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01231
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847973
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960508
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06451
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56062
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66199
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3767
E2F4	ENCODE Transcription Factor Targets	1.0	null
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62606
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19334
KDM5B	ENCODE Transcription Factor Targets	1.0	null
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5977
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
HS578T	DepMap CRISPR Gene Dependency	1.0	2.00227
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11723
UMUC9	DepMap CRISPR Gene Dependency	1.0	9.14782
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.53
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37451
PLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1215
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2894
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7717
CLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17059
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2883
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8684
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37009
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928904
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.735
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841172
LRRC4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19367
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96804
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41216
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5710-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7891
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
CORL23	DepMap CRISPR Gene Dependency	1.0	8.17107
HUNS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83899
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4073
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8673
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4329-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18881
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74478
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31764
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78138
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34438
GSE147669_2_v_1_tram2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM171A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69833
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918163
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1986
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16545
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.623
FOXRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79371
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15062
ZNF786	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48806
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8933
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27004
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83821
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
EXOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19712
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35208
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01231
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00763
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.57656
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13384
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18269
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893442
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.851376
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61301
ONS-76	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
Kidney Chromophobe_KICH_TCGA-KL-8332-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3059
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34315
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8102
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26724
DENR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43861
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90498
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05015
JAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61152
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08357
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40846
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96034
MYBPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53955
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3641
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12466
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.03216
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08072
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1781
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17981
Sensory Perception	Reactome Pathways 2024	1.0	null
ZBTB33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66627
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66409
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62402
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5888
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49132
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40249
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66024
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14948
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8655
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70242
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00593
HBEGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09511
biological_process	GO Biological Process Annotations 2015	1.0	null
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
Aicardi-Goutieres syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
FTC133	CCLE Cell Line Gene CNV Profiles	1.0	1.47248
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QM-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92291
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57806
Testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.277
NOMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83938
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03214
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23463
Rectum adenocarcinoma_READ_TCGA-AG-3742-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1525
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.39167
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5556
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59519
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15305
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0392
HDAC2	ENCODE Transcription Factor Targets	1.0	null
NCI-H2171	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6377
SNU626	DepMap CRISPR Gene Dependency	1.0	5.05885
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87154
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.961524
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64328
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63492
SW1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20366
SKMEL24	DepMap CRISPR Gene Dependency	1.0	2.24496
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.727
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73823
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14169
JHH1	DepMap CRISPR Gene Dependency	1.0	3.33442
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7452
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888995
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2557
Lung adenocarcinoma_LUAD_TCGA-MP-A4TK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83704
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9125
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6296
PECAPJ49	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44696
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97484
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74285
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90531
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.372
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.733
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74401
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8063
CHCHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24474
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8809
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6474
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80365
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02105
ZNF507	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59557
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
EBF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48589
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0931
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87555
inferior frontal gyrus, opercular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952631
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837159
Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41691
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.969005
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89022
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23273
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46852
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBE2Q2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40836
Acute Myeloid Leukemia_LAML_TCGA-AB-2976-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05996
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958123
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.861971
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0449
GSE123105,GSE124556_0_v_3_pcf11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
GSE146840,GSE146842_1_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5669
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14025
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38642
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845822
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27635
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32551
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.05074
H3K9me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81174
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1691
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38063
CHD1	ENCODE Transcription Factor Targets	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2095
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01407
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17411
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
TTC30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847973
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30552
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45815
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83647
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67965
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48403
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55809
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40305
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10093
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18551
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2903
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56466
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1376
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39691
KMRC20	CCLE Cell Line Gene CNV Profiles	1.0	1.58677
CL11	CCLE Cell Line Gene CNV Profiles	1.0	1.72216
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35755
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899333
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31101
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6219-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902849
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0949
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8147
SLC27A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77792
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41507
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83335
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43601
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68436
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6521
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
TRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76422
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4870-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892209
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97056
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19775
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33538
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34766
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13815
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62359
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
CNPPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52577
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45735
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840798
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76973
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3145
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32101
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98114
KCNF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58051
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17454
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.20138
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3856
NCI-H441	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00763
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62194
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.585824
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9697
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55319
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936891
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62359
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9938
TO14	DepMap CRISPR Gene Dependency	1.0	3.49378
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33301
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39955
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.21755
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2021
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5207
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.60812
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38424
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.3351
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902849
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03903
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05439
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927228
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39426
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11086
SNU886	DepMap CRISPR Gene Dependency	1.0	2.22344
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60871
H1-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99308
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8523
SENP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5584
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94115
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04964
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
HCC1428	DepMap CRISPR Gene Dependency	1.0	2.60137
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04707
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94036
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.81559
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8261
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.898225
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65557
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2854-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27857
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.12861
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97484
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4355
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10557
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.48687
Lung adenocarcinoma_LUAD_TCGA-44-8117-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4636-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05685
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.04662
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18441
Ribonuclease H2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954319
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36612
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
BL3752 (CBX8)	NURSA Protein Complexes	1.0	null
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.5887
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0133
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
SNU626	CCLE Cell Line Gene CNV Profiles	1.0	1.48407
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56974
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98339
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05082
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74356
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61743
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5568-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70354
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41739
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.961
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51169
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9518
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80627
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81958
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43879
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75712
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56067
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97769
Lung adenocarcinoma_LUAD_TCGA-75-7027-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.37853
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.338
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36633
PKNOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01818
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80316
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2585
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28053
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
JAK2_knockout_79_GSE26188	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.59203
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99352
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27981
ZNF440	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33234
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40803
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06838
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8952
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32845
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94713
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6044
KLF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58137
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02269
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41691
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24325
C32	DepMap CRISPR Gene Dependency	1.0	2.55916
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.462
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MH-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74979
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F3-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.898225
ZNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7902
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26411
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.61
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15221
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.941871
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19589
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6604
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.931581
NLRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04034
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00034
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88962
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0579
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869759
cis-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.478
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69841
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19802
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9505
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888416
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38131
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46343
HD-MY-Z	COSMIC Cell Line Gene Mutation Profiles	1.0	null
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27235
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61083
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98105
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2426
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6804
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902849
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55069
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0417
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59968
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00712
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.945415
RCOR1	ChEA Transcription Factor Targets	1.0	null
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49157
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903734
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43419
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906385
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5929
ZNF433	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44264
ESCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61561
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854883
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.525
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2454
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24906
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42411
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954319
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.06792
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51013
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36893
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0255
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29694
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84546
H103	DepMap CRISPR Gene Dependency	1.0	2.2802
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10834
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889078
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03845
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34871
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50446
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46511
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69613
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07193
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77246
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87073
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33951
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1147
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5110-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5737
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847973
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2013
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69278
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NB-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.84853
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73404
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57167
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HY-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6072
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94482
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48705
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71026
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64408
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33848
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58287
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79044
C99	DepMap CRISPR Gene Dependency	1.0	3.4117
LS	DepMap CRISPR Gene Dependency	1.0	8.33302
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954319
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6277
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87661
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3042
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00234
SARS-CoV MA15_Day2-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.11273
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69278
HPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78332
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29553
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
Lung adenocarcinoma_LUAD_TCGA-55-6543-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22453
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J3-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL2587 (NCOR2)	NURSA Protein Complexes	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88593
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51284
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0734
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17335
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0147
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64137
planum polare, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860974
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847973
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9338
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.35715
Perturb_7481_KD_PCDHA4_SRP150629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.65653
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04469
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37026
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11086
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09945
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963514
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.85565
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06314
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04608
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32815
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
SNU16	DepMap CRISPR Gene Dependency	1.0	7.94114
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97484
Arsenic	CTD Gene-Chemical Interactions	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LCLC97TM1	DepMap CRISPR Gene Dependency	1.0	2.14408
FAM86B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1689
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6226
ZNF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96848
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04964
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30862
chr7_144076286_T_TATA_b38	GTEx eQTL 2025	1.0	1.17632
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08153
ZNF326	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33991
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03721
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
Gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61087
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864059
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883663
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79384
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4702
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856843
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03613
PRR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22388
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873004
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47735
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15066
COLO-320-HSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11002
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19446
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2268
cell part	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864059
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04817
Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	3.50257
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1954
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.38669
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18763
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96098
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.932999
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13659
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33047
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48634
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883657
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.660042
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99758
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99902
MIXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31527
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47188
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.602743
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65768
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4865
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7567-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02265
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.28391
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88962
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08073
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21906
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35157
496100408_PCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14464
ANKRD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27075
THEMIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41002
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60729
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01371
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22557
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3574
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13964
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78083
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968392
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.49862
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986108
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65213
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15324
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5766-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70509
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56416
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02105
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29162
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954319
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6888
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6344
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26091
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66259
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77645
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9586
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09848
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95441
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83057
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07042
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871713
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.40343
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9606
LPIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71251
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.727353
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48369
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4854-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52378
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1522
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00435
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58285
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904426
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57999
HCC1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4701
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77E-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11191
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05685
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3223
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
TC71	DepMap CRISPR Gene Dependency	1.0	4.90853
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59692
STARD3NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17705
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01365
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0103
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
TKKK	DepMap CRISPR Gene Dependency	1.0	2.55841
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.553952
PSS008	DepMap CRISPR Gene Dependency	1.0	2.26718
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44277
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884392
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92802
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8608
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00008
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70892
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12097
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12984
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1074
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67982
TFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39496
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0331
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.869963
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70781
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906385
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05685
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918409
ENTREP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67309
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87721
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66955
RAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50784
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58854
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20481
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53968
Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49999
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43855
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2033
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.71893
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.706
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840798
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1931
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853992
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.853731
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-0.898225
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26018
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50446
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.865257
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94111
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05981
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97015
DHTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44952
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
HOS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76787
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30735
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.59008
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908472
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22749
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60559
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.30055
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36931
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3986
membrane part	GO Cellular Component Annotations 2015	1.0	null
UBR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78125
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903605
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64949
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45021
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86611
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14861
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.74418
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839234
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16163
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65687
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5738
RBBP5	ENCODE Transcription Factor Targets	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.85599
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1295
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12159
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23071
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05633
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6101
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2199
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3289
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20286
Fruit consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.31812
HDAC1	ENCODE Transcription Factor Targets	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89023
RPMI-8402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31623
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.00836
Endoplasmic reticulum-Golgi intermediate compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8024
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4044
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52522
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98209
Lung adenocarcinoma_LUAD_TCGA-44-7662-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889078
A101D	CCLE Cell Line Gene CNV Profiles	1.0	2.14168
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05109
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55233
PIFO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66907
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.57144
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE186647,GSE217288_2_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03903
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11086
CDKN2AIPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27139
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0417
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92531
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
C4I	DepMap CRISPR Gene Dependency	1.0	2.0502
TE14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37469
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903233
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9286
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
PPP1R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83704
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94151
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60581
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
RC3H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55941
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65945
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.3834
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZL-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915451
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5815
posterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94978
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32671
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
RPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73186
Perturb_6746_KO|KD_UPF3B|UPF3A_SRP327782	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02454
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
PRPF38A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90368
VPS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98919
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.9919
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6442
MEG-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03845
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35225
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60923
Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24479
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63409
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89092
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7840-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04964
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0592
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.898225
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89472
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1895
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48749
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52528
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5207
Lung adenocarcinoma_LUAD_TCGA-55-8621-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33222
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.09395
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23855
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3776
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87854
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91569
Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A101D	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.84507
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4899-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.995986
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22699
DTX3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84199
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5364
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.1888
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72244
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33284
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81921
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38912
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857345
ZNF808	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05247
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19765
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40753
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14796
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96271
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8191
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.72363
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50167
LN464	DepMap CRISPR Gene Dependency	1.0	2.99582
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17999
Signaling by GPCR	Reactome Pathways 2014	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847973
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5364-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65408
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15273
IFI16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87871
RAB3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25259
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30285
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.871363
OVCAR5	CCLE Cell Line Gene CNV Profiles	1.0	2.42253
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66943
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15516
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11348
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68672
CDIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78014
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41441
receptor activity	GO Molecular Function Annotations 2015	1.0	null
KLHL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22185
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98866
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4415
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889078
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21707
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A0TN-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870735
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889784
UQCRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88453
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60271
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3316-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIM2	DepMap CRISPR Gene Dependency	1.0	2.74939
NFIA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
KO52	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2575
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66097
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03237
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25403
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59672
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21519
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5359
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.464
SKOV3	DepMap CRISPR Gene Dependency	1.0	2.95438
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62546
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6273
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2472
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6716
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25153
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HT1376	DepMap CRISPR Gene Dependency	1.0	2.35021
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52296
SNU601	DepMap CRISPR Gene Dependency	1.0	4.67225
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.471
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29373
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23078
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49974
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17892
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4269
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21777
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4963-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0292
AXIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39929
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05944
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6272
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15938
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20732
chr7_144171477_G_A_b38	GTEx eQTL 2025	1.0	2.62218
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90637
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17636
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.93957
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54768
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46839
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08998
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93684
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6822
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4872-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28438
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3437
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91713
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27147
Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23107
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4768-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.2793
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18472
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15378
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96072
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16067
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28399
COLO829	CCLE Cell Line Gene CNV Profiles	1.0	1.41138
RFX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48439
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843285
GLI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63514
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53233
S117	DepMap CRISPR Gene Dependency	1.0	3.00154
PL18	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
HEYA8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44372
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98298
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5184-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27374
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2685
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19797
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827504
NCIH727	DepMap CRISPR Gene Dependency	1.0	2.3261
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	1.68233
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20685
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50985
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02125
CARD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49425
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07397
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77217
PRPF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49453
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.111
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05471
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37625
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30406
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11554
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21237
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4019
BEST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72096
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67451
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86359
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61736
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57181
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.575
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8356
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7397-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG63	DepMap CRISPR Gene Dependency	1.0	2.38517
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.98889
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3804
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04548
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57224
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	2.23921
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0918
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8438
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84754
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01711
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
SW948	DepMap CRISPR Gene Dependency	1.0	2.32546
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5718
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.905256
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27464
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6046
KNS81	DepMap CRISPR Gene Dependency	1.0	2.32697
PPP1R13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36815
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86946
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69238
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08352
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04935
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11732
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.913754
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24583
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9305
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.11927
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35212
HIC1_01_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.94718
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7925-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1166
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06297
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47521
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
KRBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24491
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-83-5908-01A-21R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07439
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39783
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48455
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00344
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50445
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10236
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93358
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JX-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69522
LMNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52991
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917552
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7947
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44125
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36837
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956108
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32228
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.82708
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89092
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38467
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98737
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57176
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01023
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01788
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74852
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71U-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.956
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93944
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.52376
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8802
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19608
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01798
Prostate adenocarcinoma_PRAD_TCGA-CH-5738-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.986697
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50359
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.587
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12937
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96176
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
response to stimulus	GO Biological Process Annotations 2015	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.418
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.28025
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
AMO1	DepMap CRISPR Gene Dependency	1.0	2.53684
MERO14	DepMap CRISPR Gene Dependency	1.0	5.0772
PBX1	ChEA Transcription Factor Targets	1.0	null
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40553
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36528
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25121
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9006
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.75132
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3173
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86941
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4924
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44454
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64979
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39246
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73741
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70325
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44312
ZNF100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91008
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3109
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71068
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05957
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64407
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0306
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17636
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74845
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.3593
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30309
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.15
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30176
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00234
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5635-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33828
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902849
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP92	CCLE Cell Line Gene CNV Profiles	1.0	2.13757
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30935
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36155
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46841
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6523
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04241
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.74361
ESO26	DepMap CRISPR Gene Dependency	1.0	3.99577
NCIH1563	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61606
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20715
C32	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872621
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.38632
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956436
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23943
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68753
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86162
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.6175
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78984
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
HNF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36517
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99775
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.946562
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91087
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900004
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
CREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94741
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857166
NCIH1339	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5756
ZSCAN16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08375
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59716
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31149
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03452
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52113
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26776
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8493
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3823
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.941045
TE-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.07583
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72697
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07299
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35836
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89838
NR2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88045
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02523
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57359
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93812
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84174
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2407
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69398
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14211
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52129
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6981-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
SW872	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63168
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93126
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09419
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05867
TBRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47612
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.264
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0662
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
Kidney Chromophobe_KICH_TCGA-KL-8325-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98891
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.965256
NCIH3122	DepMap CRISPR Gene Dependency	1.0	2.70806
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69613
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83204
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981264
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0927
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1649
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54569
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982086
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.7649
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7018
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62359
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77621
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4047
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0