association dataset threshold value standardized value Nobox JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 43.1842 Signaling by GPCR Reactome Pathways 2014 1.0 null NR1I2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7046 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.016 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08903 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE193351_4_v_0_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31707 SNU1079 DepMap CRISPR Gene Dependency 1.0 2.61521 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UOK101 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.49939 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.28844 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8964 496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18698 GSE119345_0_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures 1.0 null HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1477 TP53BP1_KD_GSE54268_670_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.591518 OVOL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2288 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0028 OVSAHO CCLE Cell Line Gene CNV Profiles 1.0 1.47597 A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903625 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848602 PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2423 THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.4341 U251MG DepMap CRISPR Gene Dependency 1.0 2.25658 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.29218 THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.98554 THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.8605 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7386 SKCO1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.8702 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.969018 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14919 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3364 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4986 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0599 lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54706 M059J Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42241 Coronary artery smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.94 Dengue shock syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.6622 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 92.8934 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.9051 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.9816 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 118.641 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3544 TFEC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0791 LS513 DepMap CRISPR Gene Dependency 1.0 5.44333 Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 227.957 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8531 Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.9764 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.608 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stereocilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.789 Prostate adenocarcinoma_PRAD_TCGA-EJ-8468-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 115.397 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IU-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8264-01B-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84G-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9767 Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 64.457 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9533 CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02185 GSE193351_4_v_2_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A878-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7831 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44511 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 78.797 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.4656 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6369 molecular transducer activity GO Molecular Function Annotations 2015 1.0 null ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0527 signaling receptor activity GO Molecular Function Annotations 2015 1.0 null Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.0724 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9198 Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 61.7513 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 70.1814 GSE193351_1_v_0_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6444 MM253 DepMap CRISPR Gene Dependency 1.0 3.77394 SNU46 CCLE Cell Line Gene CNV Profiles 1.0 1.57978 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2301 MV411 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.0395 DBTRG05MG Achilles Cell Line Gene Essentiality Profiles -1.0 -1.59702 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5853 MOLM13 Achilles Cell Line Gene Essentiality Profiles 1.0 1.06557 Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RXRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.7453 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.3046 CREM JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.678 CA SKI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68857 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.932334 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.862201 Creb3l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.8955 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.5598 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4428 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 135.179 NCIH2452 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.12295 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5414 GSE155031_5_v_1_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 59.6172 Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3923 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GL-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4102-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YKG1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.28321 cellular_component GO Cellular Component Annotations 2015 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.3158 GSE186647,GSE217287_1_v_3_hnrnpc_human RummaGEO Gene Perturbation Signatures 1.0 null Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 64.8989 Golgi membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.282 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28188 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5928 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3622 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5676 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9667 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5138 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4917 Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9862 precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12972 CAOV3 Achilles Cell Line Gene Essentiality Profiles 1.0 1.04272 BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8598 Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 85.4561 ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1682 JM1 CCLE Cell Line Gene CNV Profiles 1.0 1.4012 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.072 Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30853 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.860572 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3413 ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8713 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 89.5717 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.3129 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00211 Lung adenocarcinoma_LUAD_TCGA-44-7661-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.968456 FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.463 CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7215 HPAFII Achilles Cell Line Gene Essentiality Profiles -1.0 -1.43519 TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3636 CAOV4 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3326-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ikzf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 107.757 QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08202 cingulate gyrus, frontal part, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.916773 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.903 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null OCIAML2 DepMap CRISPR Gene Dependency 1.0 3.74706 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.987 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7909 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02185 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04287 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.855912 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.842647 GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.35162 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.819 MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1911 septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.831049 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0017 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.1667 Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1062 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.3901 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.552 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.7451 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.4186 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0922 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 104.201 Prdm14 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.3558 Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.3729 PC3 CCLE Cell Line Gene CNV Profiles 1.0 1.68493 Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 68.4362 496100446_TCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0314 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.994034 RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2589 CAL120 CCLE Cell Line Gene CNV Profiles -1.0 -1.60907 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872954 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08903 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.2203 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8126 receptor activity GO Molecular Function Annotations 2015 1.0 null RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.3043 WSU-FSCCL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.905035 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.934067 Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06669 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null Expression and translocation of olfactory receptors Reactome Pathways 2024 1.0 null icSARS CoV_48Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.37849 Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.1652 KMS26 CCLE Cell Line Gene CNV Profiles -1.0 -1.36843 Brain Lower Grade Glioma_LGG_TCGA-DU-5853-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null IGROV1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.08575 SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5446 SF126 DepMap CRISPR Gene Dependency 1.0 4.65159 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25887 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7178 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 93.9199 BL3720 (KDM4B) NURSA Protein Complexes 1.0 null KE37 DepMap CRISPR Gene Dependency 1.0 3.13268 MON DepMap CRISPR Gene Dependency 1.0 3.5127 AMO1 DepMap CRISPR Gene Dependency 1.0 2.1415 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6706 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.996873 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44927 Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07996 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.6961 Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 82.3093 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5555 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.9412 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.661655 CHD1-26751641-CHIP-SEQ-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CAL78 CCLE Cell Line Gene CNV Profiles -1.0 -1.98345 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.544 PMC11652211-Table1.docx-0-SMYD3_SMYD3 Rummagene Transcription Factor Associations 2026 1.0 null POU2F2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.0628 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25887 OLIG3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9828 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.13776 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9092 K029AX DepMap CRISPR Gene Dependency 1.0 3.59191 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6623 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.5283 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 69.5773 Luteal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.794 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6847 Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 84.4167 small-subunit processome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.19 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 122.305 olfactory receptor activity GO Molecular Function Annotations 2025 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 107.814 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.860572 GCM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9496 Creb5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 63.5546 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00459 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKMM2 Achilles Cell Line Gene Essentiality Profiles 1.0 1.35063 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.968912 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3261 CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null BSX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3334 NCIH2342 CCLE Cell Line Gene CNV Profiles 1.0 1.42865 Lung adenocarcinoma_LUAD_TCGA-99-8032-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3416 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74723 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27473 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 54.5499 Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 102.475 DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.832 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5843-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1 DepMap CRISPR Gene Dependency 1.0 6.23299 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2905 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.8536 RARB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0483 MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -2.58042 Crx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.6829 JHOM1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.50012 FOXG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9929 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.167 ACHN Achilles Cell Line Gene Essentiality Profiles -1.0 -1.14716 REST JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.1029 Npas4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.9127 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.922173 PL18 COSMIC Cell Line Gene Mutation Profiles 1.0 null PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7153 496100336_TCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.1276 H2731 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hoxa11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.4257 pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46189 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 163.741 K562 DepMap CRISPR Gene Dependency 1.0 3.49099 Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G402 DepMap CRISPR Gene Dependency 1.0 2.77986 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8923 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19678 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7575 Isl1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 47.893 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0603 OVISE CCLE Cell Line Gene CNV Profiles -1.0 -1.78174 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0712 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.17878 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 64.2458 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3231 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2964 KARPAS1718 DepMap CRISPR Gene Dependency 1.0 2.44846 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3237 DEL DepMap CRISPR Gene Dependency 1.0 2.76767 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null 496100546_TCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.51585 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3324 Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 105.918 Syntrophin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.651 GATA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5313 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9037 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38001 dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.962021 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 80.4444 GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null SW480 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.49053 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.1819 GB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.7232 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.81988 Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1686 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9613 Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.8538 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2133 HEC59 CCLE Cell Line Gene CNV Profiles -1.0 -1.51061 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9928 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MEIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6417 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00016 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74312 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.905035 transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null NCI-H596 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48414 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.870549 signal transduction GO Biological Process Annotations 2015 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19678 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4724 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9378 HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5721 KMS27 CCLE Cell Line Gene CNV Profiles 1.0 1.66971 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.1605 Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 103.116 VMRC-LCD COSMIC Cell Line Gene Mutation Profiles 1.0 null MONOMAC6 Achilles Cell Line Gene Essentiality Profiles 1.0 1.90954 llcmk2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.127 Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2881-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UMRC3 DepMap CRISPR Gene Dependency 1.0 6.09162 Dlx5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.1187 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.947251 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08578 OLIG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7703 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7245 EN2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2079 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.70755 Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9492 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE160817_7_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.16796 RMGI DepMap CRISPR Gene Dependency 1.0 2.35773 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 425.646 cingulate gyrus, parietal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.961773 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52658 RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7964 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4848-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.59333 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.788 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE193351_4_v_3_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE193351_1_v_2_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6157 temporal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26054 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3657 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.94229 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848602 plasma membrane GO Cellular Component Annotations 2015 1.0 null TT2609-C02 COSMIC Cell Line Gene Mutation Profiles 1.0 null PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.013 DU4475 CCLE Cell Line Gene CNV Profiles 1.0 1.78126 Lung adenocarcinoma_LUAD_TCGA-55-A48X-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7675 G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848602 Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 96.2967 JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.999729 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.637 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.1278 Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BDCM CCLE Cell Line Gene CNV Profiles -1.0 -1.79616 Signal Transduction Reactome Pathways 2014 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2428 SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6326 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5251 SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6355 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.1424 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5715 MDAMB453 CCLE Cell Line Gene CNV Profiles 1.0 1.40362 NCIH1568 CCLE Cell Line Gene CNV Profiles -1.0 -1.75716 NB7 COSMIC Cell Line Gene Mutation Profiles 1.0 null S117 CCLE Cell Line Gene CNV Profiles 1.0 1.97246 TOV21G DepMap CRISPR Gene Dependency 1.0 2.44007 Olig2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.4041 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.804 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.9824 SNU407 CCLE Cell Line Gene CNV Profiles 1.0 1.64673 Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848602 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.7406 Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 105.804 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1444 Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 111.27 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 236.801 Sox3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 55.1117 Brain Lower Grade Glioma_LGG_TCGA-HT-A616-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50504 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6293 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0343 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05752 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.48087 Erg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 136.839 NCIH660 Achilles Cell Line Gene Essentiality Profiles 1.0 1.13873 lateral hypothalamic area, mammillary region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26014 inferior frontal gyrus, opercular part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.942997 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.618 KYSE510 DepMap CRISPR Gene Dependency 1.0 2.3739 ONS-76 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE130401_4_v_3_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4403 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5854-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02965 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 74.3894 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.947251 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.0733 HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6201 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.002 Brain Lower Grade Glioma_LGG_TCGA-HT-7481-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2087 central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.884591 gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.95812 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.922173 Lung adenocarcinoma_LUAD_TCGA-55-8619-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dlx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.6484 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5271 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.0632 Lung adenocarcinoma_LUAD_TCGA-69-7974-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL285 DepMap CRISPR Gene Dependency 1.0 2.32695 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0487 Lhx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 55.8767 Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.381 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3415 SKNFI CCLE Cell Line Gene CNV Profiles -1.0 -1.94959 CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.36131 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Arntl JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.3814 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921348 RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4426 Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 68.6651 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44432 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7286 ventral tegmental area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.37954 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A774-01A-21R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04107 RVH421SKINFV1 DepMap CRISPR Gene Dependency 1.0 3.03293 CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 1.55903 Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 71.6778 GSE135030_3_v_0_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null Arid5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 60.3367 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.14791 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5344 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7514 OACP4C COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 496100661_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.91051 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04287 HCC1500 CCLE Cell Line Gene CNV Profiles 1.0 1.5989 OCI-AML5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.996873 supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.960806 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3705 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.2843 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2049 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0814 ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8173 TEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9451 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 57.539 globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.904602 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.4651 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40539 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 70.7617 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cornelia de Lange syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.121 Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 97.4132 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.8016 POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.7398 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2015 1.0 null GSE211425_1_v_0_mettl3_human RummaGEO Gene Perturbation Signatures -1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44739 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25504 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0826 SOX13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3623 Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 61.1126 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.90792 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 69.9925 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1965 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.60448 membrane LOCATE Predicted Protein Localization Annotations 1.0 null medial parabrachial nucleus,right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02789 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 128.25 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.9037 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4134 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6364 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8202 496100326_TCx_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.41949 preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.9603 Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.939315 NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77453 MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8926 Neurod2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 162.009 regulation of cellular process GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 102.216 CAL148 CCLE Cell Line Gene CNV Profiles 1.0 1.38444 biological_process GO Biological Process Annotations 2015 1.0 null NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0534 response to stimulus GO Biological Process Annotations 2015 1.0 null CAL51 DepMap CRISPR Gene Dependency 1.0 2.0628 ONDA9 DepMap CRISPR Gene Dependency 1.0 2.28174 Sarcoma_SARC_TCGA-VT-A80G-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100379_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.256 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.9565 Lung adenocarcinoma_LUAD_TCGA-55-7574-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OLIG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8434 NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 2.4653 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0022 RD CCLE Cell Line Gene CNV Profiles -1.0 -2.35567 SW1088 DepMap CRISPR Gene Dependency 1.0 2.27251 Alx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 92.2523 496100563_PCx_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42367 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 143.384 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 188.225 Nr5a2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.941 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20612 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5345 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.947251 Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 88.1658 Zic3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 115.463 LN235 Achilles Cell Line Gene Essentiality Profiles 1.0 1.4626 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14741 ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.667 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5768 HDQP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.59267 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2025 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.91675 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3496 Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00103 496100368_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.10554 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.999729 Sebocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.839 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2889 Foxf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 64.8832 regulation of biological process GO Biological Process Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3736 SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.2929 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.46797 KATOIII CCLE Cell Line Gene CNV Profiles -1.0 -1.59515 Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 114.553 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.886013 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6198 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.7759 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.9678 496100371_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.83268 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.861856 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48414 detection of chemical stimulus GO Biological Process Annotations 2015 1.0 null POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.6167 SOX14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4975 Plagl1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.0426 SW1271 CCLE Cell Line Gene CNV Profiles 1.0 2.42484 molecular_function GO Molecular Function Annotations 2015 1.0 null HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.939315 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5553-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05801 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848602 GSE149359_2_v_1_asap2_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-7944-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rhox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.4123 C4II DepMap CRISPR Gene Dependency 1.0 2.8535 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 68.6275 Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 76.9113 ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.9812 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.18363 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31707 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 86.2208 Thyroid GTEx Tissue Gene Expression Profiles 2023 1.0 7.21239 Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.2414 YMB1 CCLE Cell Line Gene CNV Profiles 1.0 1.75501 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5257 PSN1 DepMap CRISPR Gene Dependency 1.0 2.01615 sirolimus_homo sapiens_gpl6244_gse15703 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5057 PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7492 496100408_PCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.23478 GPCR downstream signaling Reactome Pathways 2014 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6297 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27264 KIJK DepMap CRISPR Gene Dependency 1.0 5.16193 NCIH2171 Achilles Cell Line Gene Essentiality Profiles 1.0 1.33707 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.3011 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6133 olfactory receptor activity GO Molecular Function Annotations 2015 1.0 null HOXC10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2874 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.4628 detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chromosome, subtelomeric region COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.618 integral component of membrane GO Cellular Component Annotations 2015 1.0 null Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 47.8706 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3343-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8313 NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.996526 Olfactory Signaling Pathway Reactome Pathways 2024 1.0 null Amastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.708 OPM2 DepMap CRISPR Gene Dependency 1.0 2.47617 HCC78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893343 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5404 septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.879102 cell part GO Cellular Component Annotations 2015 1.0 null Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 102.257 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20612 PMC11015551-12915_2024_1879_MOESM8_ESM.xlsx-depmap_predictability_data_REST-feature_REST Rummagene Transcription Factor Associations 2026 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54795 G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9024 Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 133.028 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921348 Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE410 DepMap CRISPR Gene Dependency 1.0 2.26648 kidney GTEx Tissue Gene Expression Profiles 1.0 1.31319 Sensory Perception Reactome Pathways 2024 1.0 null Lhx8 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0847 Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Preribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.899 BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1361 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19067 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2889 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6802 HSC2 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38001 FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1336 Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.4786 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.4098 NCO2 CCLE Cell Line Gene CNV Profiles -1.0 -1.50964 P2URK562 DepMap CRISPR Gene Dependency 1.0 2.67964 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5311 NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8059 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848602 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39274 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2023 1.0 null superior rostral gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.894225 Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2176 ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8498 BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8034 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.99348 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3143 496100544_PCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43856 IRX1_01_227 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60864 SNU349 CCLE Cell Line Gene CNV Profiles -1.0 -1.58897 Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sox6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 66.2249 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null Foxn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.7456 Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.391 BHLHE41 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4204 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21431 sensory perception of smell GO Biological Process Annotations 2023 1.0 null NCIH2087 DepMap CRISPR Gene Dependency 1.0 2.43024 blood GTEx Tissue Gene Expression Profiles 1.0 1.36855 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 73.0956 ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.15 TFEB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9763 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25887 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JD-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 85.6449 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0816 SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.729308 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 63.0682 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6024 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1441 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 95.2553 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2025 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2779 HCC2218 CCLE Cell Line Gene CNV Profiles 1.0 1.67229 Lhx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.9905 Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 116.607 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dystrophin-associated glycoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.241 MDAMB453 Achilles Cell Line Gene Essentiality Profiles 1.0 1.47361 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.861856 ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9829 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8291 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE193351_1_v_3_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74499 Lung adenocarcinoma_LUAD_TCGA-44-A47G-01A-21R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7719 Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 98.9755 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.940666 WM3772F DepMap CRISPR Gene Dependency 1.0 2.51703 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04297 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.1725 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13892 Olfactory Signaling Pathway Reactome Pathways 2014 1.0 null LN229 DepMap CRISPR Gene Dependency 1.0 3.1671 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.922173 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 301.763 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03195 Coronary artery smooth muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.954 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04195 Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9397 HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4126 NCIN87 Achilles Cell Line Gene Essentiality Profiles 1.0 1.05207 nucleus of the diagonal band, left, horizontal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30419 Brain Lower Grade Glioma_LGG_TCGA-P5-A730-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7959 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8779 CALU1 Achilles Cell Line Gene Essentiality Profiles -1.0 -2.1204 CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872127 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9934 M07E DepMap CRISPR Gene Dependency 1.0 2.86976 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.4261 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Elf5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 191.481 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.8719 dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.925996 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7314 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.870549 Lung adenocarcinoma_LUAD_TCGA-86-8054-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 75.4511 Six3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.2022 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 145.157 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848602 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6417 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04446 PSN1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.17714 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.624 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.554 nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.85357 TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 66.7945 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.601 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.6791 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5045 JHH6 CCLE Cell Line Gene CNV Profiles 1.0 1.48332 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1885 HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6464 Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 58.5021 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MM383 DepMap CRISPR Gene Dependency 1.0 2.40012 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9761 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tfcp2l1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 43.5416 MOLP2 CCLE Cell Line Gene CNV Profiles -1.0 -2.09395 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8158 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6308 NALM6 DepMap CRISPR Gene Dependency 1.0 2.07115 Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87J-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PECAPJ15 DepMap CRISPR Gene Dependency 1.0 2.19109 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.81502 BHY CCLE Cell Line Gene CNV Profiles -1.0 -1.47617 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5848 Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 111.402 H157 DepMap CRISPR Gene Dependency 1.0 2.24939 SUDHL4 CCLE Cell Line Gene CNV Profiles -1.0 -1.44125 Olfactory receptor InterPro Predicted Protein Domain Annotations 1.0 null OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09628 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.931 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.3996 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.2644 Lung adenocarcinoma_LUAD_TCGA-49-4505-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 117.119 Nr1h2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.4358 Hypopharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.776 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44432 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3309 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2997 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8904 CAOV-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28107 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1044 signal transducer activity GO Molecular Function Annotations 2015 1.0 null PITX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8118 sensory perception of smell GO Biological Process Annotations 2025 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3454-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6385 HCC1143 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.854659 496100414_TCx_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.86515 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1623 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3497 Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.283 Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.273 membrane GO Cellular Component Annotations 2015 1.0 null FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8595 JHESOAD1 DepMap CRISPR Gene Dependency 1.0 2.12838 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.7642 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.074 HSQ89 DepMap CRISPR Gene Dependency 1.0 2.07983 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 58.7163 MYC_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Keratin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.887 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 77.691 SK-MM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null NEUROG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0359 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10983 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 526.689 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9151 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6159 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7858 Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Npas2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.2769 U343 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.07137 GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null SW1271 COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4701-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 135.966 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28043 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.97254 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2023 1.0 null NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9014 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35684 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 150.85 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2331 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5153 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMRC20 CCLE Cell Line Gene CNV Profiles -1.0 -1.44025 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.5006 ZNF768 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9244 COR-L321 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH1975 DepMap CRISPR Gene Dependency 1.0 3.59329 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4702 Zbtb2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0599 POU2F2 ENCODE Transcription Factor Targets 1.0 null CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.909931 Lung adenocarcinoma_LUAD_TCGA-55-8510-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.6868 MYC ENCODE Transcription Factor Targets 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Longissimus thoracis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.765 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3022 WM88 DepMap CRISPR Gene Dependency 1.0 5.05825 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2121 Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.5758 Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.9396 Autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0846 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3621 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8316 STS-0421 COSMIC Cell Line Gene Mutation Profiles 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15746 NCIH1666 DepMap CRISPR Gene Dependency 1.0 2.22969 subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19067 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2441 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.977 Dmbx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 52.1205 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HS-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7994-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 74.4335 TE6 CCLE Cell Line Gene CNV Profiles -1.0 -1.44159 ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.596 HCC202 CCLE Cell Line Gene CNV Profiles 1.0 1.51954 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66675 D341Med DepMap CRISPR Gene Dependency 1.0 3.20963 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.4881 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4643 ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8862 HCC202 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.730206 EOL1 DepMap CRISPR Gene Dependency 1.0 3.13223 ETV7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8138 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5462 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 JVE015 DepMap CRISPR Gene Dependency 1.0 2.49038 Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 50.3106 Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8111 motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.867752 HCC2157 COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1197 SNU449 DepMap CRISPR Gene Dependency 1.0 2.32615 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0246 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.7452 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5675-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4061 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 86.4172 NCIH1869 CCLE Cell Line Gene CNV Profiles 1.0 1.37352 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0359 Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null SKNO1 CCLE Cell Line Gene CNV Profiles 1.0 1.49395 SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.32877 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1065 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9773 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.24625 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.82082 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.0555 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5784 CTCF ENCODE Transcription Factor Targets 1.0 null HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.78287 HS821T CCLE Cell Line Gene CNV Profiles -1.0 -1.4168 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.89937 detection of stimulus GO Biological Process Annotations 2015 1.0 null DMRTA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4702 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.10985 Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 47.5424 ZSCAN29 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6161 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 109.981 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15746 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE450 CCLE Cell Line Gene CNV Profiles -1.0 -2.194 POLR2A ENCODE Transcription Factor Targets 1.0 null Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 120.345 Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.0308 Aedesaegypti TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.156 BARX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9274 UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.687831 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88452 ASPC1 DepMap CRISPR Gene Dependency 1.0 3.71147 PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3619 Trypomastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.882 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02263 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 92.7936 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1717 SLR26 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.22371 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5686-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100366_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.71674 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZE-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null olfactory receptor activity GO Molecular Function Annotations 2023 1.0 null ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7864 Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory transduction KEGG Pathways 2026 1.0 null NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.0107 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 144.222 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78P-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 144.228 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5326 Zic1::Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 83.4625 HLF Achilles Cell Line Gene Essentiality Profiles -1.0 -1.02417 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.3949 Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.9327 membrane part GO Cellular Component Annotations 2015 1.0 null Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 96.0439 TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3464 ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0625 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.8971 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0263 g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null Twist2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.5946 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.88586 KMH-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.4478 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.7996 MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0336 496100430_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.0898 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.798104 Smad4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.116 NB5 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7056-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hoxa13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 121.133 Nkx3-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.5022 DEL CCLE Cell Line Gene CNV Profiles 1.0 2.03616