association	dataset	threshold value	standardized value
BRD-K35128023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3353
BRD-K49866832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48058
Asthma and major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72549
BRD-K39206254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70254
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88518
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMC18	CCLE Cell Line Gene Expression Profiles	1.0	1.80694
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.1165
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8207
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.66418
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.65382
IBMX	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60552
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.32808
quinidine-5793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	76.6
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0048
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.987478
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28778
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.071071
SKMEL30	DepMap CRISPR Gene Dependency	1.0	5.72765
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7194
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.43284
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0251
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.13585
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900676
BRD-K07368164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18484
BRD-K00233837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.054
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17742
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90157
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11789
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.33245
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1504
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14239
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48563
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M9-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889009
EGR1-19032775-M12-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FU97	CCLE Cell Line Gene Expression Profiles	1.0	2.21685
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06296
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.67795
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0233
BRD-K52921974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5007
BRD-K95152807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34373
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78728
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2443
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7335
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.904
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.72797
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1212
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17502
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97429
tylosin-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09452
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.72065
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28529
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.9391
BRD-K55147629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27332
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23434
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44498
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K84388104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29475
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5994
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.91606
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897519
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.98408
pentoxifylline-2290	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HARA	DepMap CRISPR Gene Dependency	1.0	2.39466
BRD-K97576000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18641
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7812-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37584671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9849
BRD-K20220643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0076
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.021
BRD-K64449549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18803
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.46248
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4810-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72865
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7368
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20846358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30464
BRD-K50191826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30912
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13283
BRD-K62800316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21848
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27394
NCIH1944	DepMap CRISPR Gene Dependency	1.0	2.06586
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1768
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00787
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878964
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89416
BRD-K76951133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92031
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2655-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Airway fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
TR146	DepMap CRISPR Gene Dependency	1.0	2.26236
BRD-K39411863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11843
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8799
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51076
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03454
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04085
BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65909
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5325
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42552
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6135
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5058
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.1598
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4259
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.63881
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1399
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23571
GI1	DepMap CRISPR Gene Dependency	1.0	5.26414
HuCCT1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65906
BRD-K55053106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5432
16081686-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K67556876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22465
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79221
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4701
BRD-K54495109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.1351
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K63487554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98898
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.1925
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19484
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9759
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10123
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01528
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEG-01	GDSC Cell Line Gene Expression Profiles	-1.0	-1.75699
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6655
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88727
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837593
SW948	DepMap CRISPR Gene Dependency	1.0	2.24276
SW954	DepMap CRISPR Gene Dependency	1.0	2.85755
BRD-K58307544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24683
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4986
BRD-K77139764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34775
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.615
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13283
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.659
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39605
CRCGN014_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21789
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	2.94575
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04283
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79009
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.50675
CTCF	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-5	GDSC Cell Line Gene Expression Profiles	1.0	1.47801
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1316
BRD-K10160311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17087
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.0624
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04108
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8231
SKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74822
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.931795
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41252
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848542
PSN1	DepMap CRISPR Gene Dependency	1.0	2.18249
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2969
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.30414
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9565
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.51599
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8695
BRD-K60661821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18611
CRCGN014_HEPG2_3H:C06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13956
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	2.42334
BRD-K21997380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15251
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.85948
BRD-K87449690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27908
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04883
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16206
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5216
PC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SQSTM1_OE_GDS2653_651_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29776
A2058	DepMap CRISPR Gene Dependency	1.0	4.64791
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.34429
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3704
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08434
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.22921
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8238
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837608
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K03213425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11131
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8283
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8471
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GPCRs, Other(Mus musculus)	WikiPathways Pathways 2014	1.0	null
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53383
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11578
REH	GDSC Cell Line Gene Expression Profiles	1.0	1.43102
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4878
GSE254848_9_v_8_ptges_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K09203354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78259
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67969
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.6604
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31348
bretylium tosilate-3057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1022
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	2.0354
BRD-K28991565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43191
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.2945
PF-382	GDSC Cell Line Gene Expression Profiles	1.0	1.70431
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34358
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16172
RMGI	DepMap CRISPR Gene Dependency	1.0	2.8229
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	0.956107
RCC10RGB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63177
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8042
CRCGN012_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2795
ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K25176380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10917
JUN	ChEA Transcription Factor Targets	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31949
BRD-K53224568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46939
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2347
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.317
triphenyl-tin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10596
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.1879
A204	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.861412
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6262
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82634
BRD-K60238549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15381
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3594
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94853
BRD-K48140215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10367
Spear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
IRF1	ENCODE Transcription Factor Targets	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15378
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31055
BRD-K95192796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.788
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82949
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68495
NCI-H2085	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0588
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.40495
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05232
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09834
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99767
biological regulation	GO Biological Process Annotations 2015	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94314
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59208
BRD-K79103937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06022
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19267
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45028
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17988
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8353
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.835
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25075
BRD-K14116382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09951
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4776
PKCTHETA-26484144-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-198-ZNF250_ZNF250	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44115
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.88501
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16404
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.09158
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.325375
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26754
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7888
BRD-A96536816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40294
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22882
STAU1_DELETION_GDS3370_56_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1555
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.12662
BRD-K69661816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9288
NCIH1836	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61808
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.922703
JHUEM1	CCLE Cell Line Gene Expression Profiles	1.0	1.40571
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6438
BRD-K29760532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69267
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62839
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14223
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28088
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OCIAML3	DepMap CRISPR Gene Dependency	1.0	2.44115
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-8.2898
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.83195
BRD-K60188481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35083
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.889211
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34471
BRD-K71283713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06096
BRD-K14055576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1761
BRD-K55345749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34008
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3316
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0605
BRD-K41645779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44857
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7279
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	0.874202
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51825
BRD-K71622214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09733
BRD-K68002543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02749
Platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0041
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K73494324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21306
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12983
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05588
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.731
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.857
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.441
BRD-K79676802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04707
SNU899	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62956
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23434
BRD-K52764062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74382
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.75
BRD-K02548315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.8937
BRD-K59657378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4377
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	0.91294
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KLE	DepMap CRISPR Gene Dependency	1.0	4.15989
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7603
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8333
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89622
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07325
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53413
membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19382
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.85597
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47857
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07653
CRCGN017_MCF10A.WT.HP_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2255
GSE60837_6_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
diphenylpyraline-6061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25565
RT11284	CCLE Cell Line Gene Expression Profiles	1.0	1.99864
BRD-K05050615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41518
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.54201
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62317
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.589
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40573
BRD-K13304927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0144
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9126
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1173
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3148
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9786
BRD-K11612998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48078
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6419
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.30382
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81159
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76533
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K33912919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21801
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20122
BRD-K97805186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0456
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.57814
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1734
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9684
BRD-K47349976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77899
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29386
BRD-K26184956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38326
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.51505
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1316
Lung squamous cell carcinoma_LUSC_TCGA-43-A475-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9774
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.37926
BRD-K59185421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23922
BRD-K37763427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5877
CRCGN008_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55925
GP5D	DepMap CRISPR Gene Dependency	1.0	5.06944
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1802
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8605
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05967
BRD-K91104058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4433
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81375
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19267
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.987478
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49156
BRD-K55642725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0324
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.10136
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3193
NCIH2087	DepMap CRISPR Gene Dependency	1.0	3.17094
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837593
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39524
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2416
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.8353
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45004
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8839
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18657
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.41557
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39846
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
WM115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49528
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46326
CRCGN013_HEPG2_24H:J04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06417
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19152
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	1.63327
SW900	CCLE Cell Line Gene Expression Profiles	1.0	1.74139
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69316
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77157
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991221
BRD-K75900905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60045
Ethanolamine ammonia-lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999593
PATU8988T	CCLE Cell Line Gene Expression Profiles	1.0	1.62531
LPS6	DepMap CRISPR Gene Dependency	1.0	2.07846
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12178
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.455
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.81165
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.15742
BRD-K56595246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74646
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8953
BRD-K28583191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03527
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35471
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46151
BRD-K73210450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52288
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3389
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	3.38447
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60499
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.7067
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02264
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5134
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972527
ICC3	DepMap CRISPR Gene Dependency	1.0	2.7984
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.5121
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1439
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
ESS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84574
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.85124
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.12632
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889009
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885641
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5025
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.21476
Arthritis, Psoriatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42972
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08797
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.69548
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870596
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-8118-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32133
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4085
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4377
BRD-K83395537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17429
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7465
BRD-K88720906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08445
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62019
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33569
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1722
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5889
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944185
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64465
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC44	DepMap CRISPR Gene Dependency	1.0	2.46458
RCHACV	CCLE Cell Line Gene Expression Profiles	1.0	1.3929
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.987478
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16849
BRD-K96063588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07577
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.10299
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29878
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.465
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34595
CRCGN011_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76135
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9771
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02521
BRD-K87530935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.9178
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4321
BRD-K21479004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94306
biological_process	GO Biological Process Annotations 2015	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.33215
furazolidone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-7.14897
IMR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-2.0456
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2854
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.453
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48675
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884896
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0692
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.5379
Interalveolar septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K70276322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32575
BRD-K76350099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1867
BRD-K01978082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.99612
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.08684
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31923
STAT1	ChEA Transcription Factor Targets	1.0	null
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81651
BRD-K34169251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09234
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8773
BRD-K14359826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.2188
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.569
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2487
BRD-K96023136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05248
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.835
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-6545-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	88.2963
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6975
H357	DepMap CRISPR Gene Dependency	1.0	2.17025
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23859
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.42487
BRD-K34556006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18305
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3704
BRD-K89555807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2819
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884896
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26994
BRD-A71880598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14741
GSE213746_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57866
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14935
KPNSI9S	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98346
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23571
HT-1376	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
BRD-K87781745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33941
Lung non-small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.597
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A5ND-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pridinol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02395
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03054
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48496
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.539
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78633
UPMD1	DepMap CRISPR Gene Dependency	1.0	3.7537
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92435
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3891
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06218
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
arthritis	GWASdb SNP-Disease Associations	1.0	0.329882
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837608
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.3824
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.13074
BRD-K36691793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08449
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2737
BRD-K13265046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06274
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884896
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38945
BRD-K35879814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19628
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3361
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869724
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MESSA	CCLE Cell Line Gene Expression Profiles	1.0	1.37958
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56432
bone disease	GWASdb SNP-Disease Associations	1.0	0.160747
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46715415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16226
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	103.148
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.22346
BRD-K60237462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53853
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5598
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4534
BRD-K37269981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47828
BRD-K72738889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50861
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5743
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11188
GSE200446_1_v_2_srsf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7104
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90794
shikonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.91064
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50481
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939364
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32345
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32411
BRD-K56065989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84308
BRD-K61629734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03834
BRD-K25016708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53834
BRD-K11258719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11674
KE39	CCLE Cell Line Gene Expression Profiles	1.0	1.68471
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.78709
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53494
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3549
BRD-K36156445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57892
NCIH23	CCLE Cell Line Gene Expression Profiles	1.0	1.66821
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76533
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	2.60386
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.884
CAOV4	CCLE Cell Line Gene Expression Profiles	1.0	2.00115
BRD-K27911943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39985
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7799
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8987
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4216
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35201
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.2485
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90938
BRD-K39464795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07876
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50892
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.43763
BRD-K58596567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12183
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5669
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.74
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
BRD-K82781769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48577
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7791
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72459
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K14756138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82032
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.945118
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75098
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DANG	DepMap CRISPR Gene Dependency	1.0	3.15907
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.60876
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63082
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.07693
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02563
PMC9860384-mmc2.xlsx-Table_S4-Table_S4_2016_VCF_Shared_Variants_related_to_the_results_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26399271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4354
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885641
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35887
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68748
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63527
KP3	CCLE Cell Line Gene Expression Profiles	1.0	1.35559
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884896
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06975
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12663
SF126	DepMap CRISPR Gene Dependency	1.0	3.12541
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	95.2112
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9659
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01013
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	3.7526
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06606
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE254848_4_v_13_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.094
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2859
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8754
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49473389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40303
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.33219
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.2694
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03054
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.769
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AD-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33703
BRD-K96575636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46759
BRD-K79152256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12007
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K99953989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02653
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.40475
EGR1	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01288
BRD-K11219023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18634
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4192
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.8126
SNU1041	CCLE Cell Line Gene Expression Profiles	1.0	1.84378
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2134
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21196
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6055
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81714
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04139
BRD-K61553906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80816
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36764776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3088
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.5049
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837608
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.025461
NCIH1975	DepMap CRISPR Gene Dependency	1.0	4.01446
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830013
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6322
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25194
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3901
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.5214
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.90818
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1376
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875991
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48684
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28935
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1653
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6303
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3437
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5999
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8201
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K21955896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50595
BRD-K59831227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14595
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15083
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41953
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6351
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chloroxylenol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98282
HEC265	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7293
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.296478
BRD-K32240435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15792
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5691
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18462
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.51811
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5391
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57991
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05692
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04139
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH2	DepMap CRISPR Gene Dependency	1.0	2.03095
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K19516614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38183
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41665
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8016
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95222
NCIH661	DepMap CRISPR Gene Dependency	1.0	4.52593
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
Lung squamous cell carcinoma_LUSC_TCGA-39-5019-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200446_0_v_3_srsf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.429
CH-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
BRD-K48171978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23921
icSARA deltaORF6_48Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.03904
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837608
receptor activity	GO Molecular Function Annotations 2015	1.0	null
SNU1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63652
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.678
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.13495
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07589
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1928
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.2236
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10579
Olfactory transduction	KEGG Pathways 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3231
NCIH1355	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50401
NCIH727	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57689
BRD-K88836117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51259
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6742
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7656
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97374
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3319
HS-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
CRCGN017_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02666
CRCGN012_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02341
Grey cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.79916
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80848
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.429
BRD-K50177531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42591
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0514
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.429
BRD-K58577862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26016
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54545
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67251
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.5925
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973014
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3834
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78994
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.72285
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4361
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884805
BRD-K78961368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69536
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05906
RH30	DepMap CRISPR Gene Dependency	1.0	4.29332
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.62475
BRD-K55640577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89251
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1158
BRD-K26431593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.55127
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.1638
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03744
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.28992
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.247908
BRD-K98190019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27192
Prestwick-674-6034	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999593
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.26327
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9227
Prestwick-675-6042	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867095
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21687
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.827532
PBX1	ChEA Transcription Factor Targets	1.0	null
GSK3B_KD_GDS4305_185_human_U937 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47941
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79213964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64475
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6856
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.08175
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27996
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.4726
P30-OHK	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51321
BRD-K56470219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45329
BRD-K18876264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02699
MONO-MAC-6	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94933
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55475
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860403
BRD-K33350866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14209
CRCGN008_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0034
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955019
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.5898
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.833
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55799
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46682
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41817
BRD-K90702747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29065
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7935
HEC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20122
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.238
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	1.0	1.33759
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14899
BRD-K87967738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06964
BRD-K77591784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42381
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5691
ZR-75-30	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64352
BRD-M31871110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05629
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28366
CRCGN014_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28007
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.8169
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6422
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0032
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38115
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8737
KON	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14210122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03184
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869724
BRD-K68149575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28452
liver	GTEx Tissue Gene Expression Profiles	1.0	1.59752
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.33136
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30445
DKMG	DepMap CRISPR Gene Dependency	1.0	3.12735
tilorone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42177
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.255
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24373
BRD-K00191683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5517
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K52379384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25724
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27922
H3K36me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9462
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6942
BRD-K05057860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02956
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22714
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16968
786	BioGPS Cell Line Gene Expression Profiles	1.0	0.8647
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	8.00283
Tongue epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7342
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32224
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.28787
SK-OV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K76706127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65207
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00251
BRD-K40960913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27711
RBBP5	ENCODE Transcription Factor Targets	1.0	null
IGR-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59093
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rara_21299862_mcf7_lof_human__gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.179399
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61795
PMC9637086-41598_2022_23176_MOESM10_ESM.xlsx-Sheet1-Table_S6_Number_of_chemical_predicted_to_be_active_on_olfactory_receptors_based_on_the_external_set_of_69_chemicals_from_the_DREAM_challenge_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49805
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08662
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9685
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2775
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2447
APP	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03019
HEC1A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92727
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23434
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.429
BRD-K06846146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87053
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.3995
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.48555
BRD-K78959251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05429
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.854
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01948
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.9783
BRD-K82050323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59801
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2482
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K98510376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28449
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01868
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24503
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.54136
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66489
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91542
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884896
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.7841
786O	CCLE Cell Line Gene Expression Profiles	1.0	1.59615
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2015
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837593
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.51585
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.235
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3642
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51813
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52794
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.801
COLO792	DepMap CRISPR Gene Dependency	1.0	2.53423
BRD-K23553911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28455
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11054
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8656
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.1092
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.806
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1903
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87486
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4534
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2053
BRD-K22698363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67862
KYSE150	CCLE Cell Line Gene CNV Profiles	1.0	2.00672
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0549
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0576
response to stimulus	GO Biological Process Annotations 2015	1.0	null
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	2.0552
BRD-K39863565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99385
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.49139
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.01798
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.51549
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02782
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.126259
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.754
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977484
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
BRD-K03070961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67686
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08238
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0905
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.89608
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973014
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.429
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.40123
BRD-K80991460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32738
BRD-K25539387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92885
Platelet alpha granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7721
NCIH1838	CCLE Cell Line Gene Expression Profiles	1.0	1.44063
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47955
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37562
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.36456
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.522
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5172
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00326
CHD1	ENCODE Transcription Factor Targets	1.0	null
NCI-SNU-16	GDSC Cell Line Gene Expression Profiles	1.0	1.62504
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.429
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27605
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33884
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40735
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7555
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.25823
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39591
5g3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
SKNAS	CCLE Cell Line Gene Expression Profiles	1.0	2.53996
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951798
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6243
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
bleomycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04433
BRD-K43192646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0376
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.53783
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71622
BRD-K87167435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03716
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KQ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43108627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49772
BRD-K97263385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97175
PSN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58617
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9889
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.71904
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2484
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.62855
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21708
Androgen insensitivity syndrome_Fibroblast_GSE3871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.50619
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.967104
BRD-K00620786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06356
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1525
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17052
BRD-K10372036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9357
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20845
PANC0327	CCLE Cell Line Gene Expression Profiles	1.0	1.36506
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0937
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80936
chloropyrazine-5750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7415
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18491
BRD-K26231789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32536
BRD-K72194126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26054
GSE226091,GSE226092_3_v_2_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.597
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	72.3034
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11465
BRD-K51296348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3445
HGC27	DepMap CRISPR Gene Dependency	1.0	2.26539
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26183
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37344
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90402
ESRRA_01_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.26611
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49514
SCARA5_Down Expression_GSE32323_611_human_Colorectal Cancer Cell lines	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31321
BRD-K20026212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03306
Daudi	GDSC Cell Line Gene Expression Profiles	1.0	1.56981
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6532
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70295
CL14	CCLE Cell Line Gene Expression Profiles	-1.0	-3.98806
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
benzbromarone-5015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.4081
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2833
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15407
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9391
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96477
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6553
Respiratory mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.752
HSF1_KD_GDS1733_752_human_HeLa cells - 2 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K66993610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53406
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tRNA-intron endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2482
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9535
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78961
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.30893
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K94196749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1332
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9448
CRCGN014_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26003
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39212
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.80082
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4543
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81633
OCI-AML2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49605
EZH2_DEPLETION_GDS2445_117_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HS695T	DepMap CRISPR Gene Dependency	1.0	2.40894
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3626
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.35165
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2488
BRD-K25408656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40426
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42307233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87887
POU3F2	ChEA Transcription Factor Targets	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.39875
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	1.09014
pantothenic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31456
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55875
BRD-K90154335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05948
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07682
BRD-K58232861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74264
GSE166944_1_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05318
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4115
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.38813
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.1041
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9947
JHH7	DepMap CRISPR Gene Dependency	1.0	2.53372
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.665
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7509
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837593
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.699
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906948
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029151
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.429
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28366
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39437
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2085	CCLE Cell Line Gene Expression Profiles	1.0	2.23303
metampicillin-5540	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5134
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52648
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94005
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.11387
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6904
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0626
PECAPJ15	CCLE Cell Line Gene Expression Profiles	1.0	2.6259
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRD-K31757099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98012
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6481
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.425
cis-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
PACADD137	DepMap CRISPR Gene Dependency	1.0	2.82656
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2585
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.0943
GATA1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46298074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60959
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7712
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.30844
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5385
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07519
Signaling by GPCR	Reactome Pathways 2014	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.1099
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50291875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0996
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88767
JAK2_knockdown_192_GSE54645	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.62317
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	135.122
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0372
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3198
BRD-K74568352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82228
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8997
BRD-K82683018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26353
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.12286
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884896
ICC4	DepMap CRISPR Gene Dependency	1.0	2.32788
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83341
ISTMES2	CCLE Cell Line Gene Expression Profiles	1.0	1.48331
BRD-A89947015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23371
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.792
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00823
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.46349
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.8793
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12015
BRD-K64862097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27783
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7836
SW1573	DepMap CRISPR Gene Dependency	1.0	2.10437
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11948
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6985
BRD-K44177046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83457
all	GWASdb SNP-Phenotype Associations	1.0	0.029123
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
metacycline-4143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.129303
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33760911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14363
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9097
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23434
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1908
NHEK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88105
U87MG	DepMap CRISPR Gene Dependency	1.0	3.51155
BRD-K31197843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55738
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905721
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.064048
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04075
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.447
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0004
BRD-K37470774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58162
BRD-K51753035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52454
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11579
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.34743
BRD-K09598619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.94311
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.63425
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926292
ZR751	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51346
BRD-K80469338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25954
BRD-K51157416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04874
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
RB1_KD_GSE50532_593_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.028865
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8158
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22694
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.18549
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1663
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23571
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.043
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.22977
BRD-K21363211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51332
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
BRD-K94889220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02984
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.0661
8MGBA	DepMap CRISPR Gene Dependency	1.0	3.40131
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8568
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6304
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.223
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.82209
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77935
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99884
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12597
BRD-K43435656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16683
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44203
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
foxa1_23539448_lncap_lof_human_gpl10558_gse37314	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.607847
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7486
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1774
BRD-K34161817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41681
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23623
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29335
BRD-K89801935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73169
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4332
BRD-K04875192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09474
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.2023
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78227
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984897
MON	DepMap CRISPR Gene Dependency	1.0	5.90484
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837608
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.194
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32027
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46544
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8707
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837593
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8908
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
thioproperazine-5791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K47555438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93093
BRD-K22481359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05309
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4605
P31-FUJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53137
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	1.36038
BRD-K19527338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65993
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884896
RARA_01_51	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.42561
BRD-K51181201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10103
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5499
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98097
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00171
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17645
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65428
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930245
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2828
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD38	DepMap CRISPR Gene Dependency	1.0	2.97903
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
BRD-K51535480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46834
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9094
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5768
BRD-K60287661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2277
BRD-K19776718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19447
BRD-K40841951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31771
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44481
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45015
BRD-K53752646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2027
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K54872884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13348
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.952
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89825
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74177
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05111
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.03305
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NOZ	DepMap CRISPR Gene Dependency	1.0	2.44123
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.274
pimasertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50195
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23043
BRD-K85917058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11302
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7063
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.213401
GATA1	ENCODE Transcription Factor Targets	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.158
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96465
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5744
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57265
BRD-K23496480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16155
BRD-K98384558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27489
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.404
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5777
Type 1 diabetes (age at diagnosis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	212.152
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.02915
SON_KD_GDS4448_35_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K03884263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15003
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7721
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1588
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39249
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52165
NCIH2122	DepMap CRISPR Gene Dependency	1.0	2.92831
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61521
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00517
Squamous cell carcinoma of lung_Lung Tissue_GSE3268	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.35249
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.8637
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5004
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.66291
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4085
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.3685
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.755771
BRD-K29655991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17124
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11253
BRD-K14723547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28234
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6965
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37221
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40412
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31622
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
Squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.597
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8527
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3522
membrane part	GO Cellular Component Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5709
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0305
icSARS CoV_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.11502
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.94799
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.28675
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28446
EGR1-19032775-M12-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.987478
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	1.04024
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Social communication problems	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.74074
BRD-K62584372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02121
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.60017
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung Injury_Lung Tissue_GSE1541	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.20763
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39761
KYSE140	DepMap CRISPR Gene Dependency	1.0	3.37665
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12843
U118	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.922886
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.49865
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.846439
BRD-K05246869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26295
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.668
BRD-K84775364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18482
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.50264
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4065
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37508
BRD-K66434795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01387
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25381
BRD-K75703503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10409
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.632
BRD-K70648728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31839
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44139185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2076
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65428
BRD-K47995524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32162
Testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.52241
dexamethasone_mus musculus_gpl5137_gse10900	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.18102
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16997
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.70566
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69842
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13048
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.827532
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79965
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.090693
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5265
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34955
JHH7	CCLE Cell Line Gene Expression Profiles	1.0	1.43221
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7443
LNCaP clone FGC	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.025
BRD-K36353158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05654
BRD-K63573625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08755
C99	DepMap CRISPR Gene Dependency	1.0	2.91935
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9967
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61515
BRD-K76477096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40337
cell part	GO Cellular Component Annotations 2015	1.0	null
Fish- and plant-related diet	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75901
BCLAF1_01_214	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.85621
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.00351
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5232
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29994
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34665