association	dataset	threshold value	standardized value
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859643
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053036
PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8203
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5931
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-8501-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42048
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91154
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41175
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.936496
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	1.56471
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3688
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7943
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.906976
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.971607
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985334
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966053
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13586
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53795
RB1_KD_GSE50532_657_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44524
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901769
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21741
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.876
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863627
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862779
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4533
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.1043
Reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.65229
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875609
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35369
Supraspliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.951754
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.14902
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19133
496100449_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07627
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05437
Prostate adenocarcinoma_PRAD_TCGA-G9-6377-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899398
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0379
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HPAC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052157
JHUEM7	DepMap CRISPR Gene Dependency	1.0	2.52742
MHHES1	DepMap CRISPR Gene Dependency	1.0	3.87663
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35659
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4756
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34346
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06869
SNU761	DepMap CRISPR Gene Dependency	1.0	5.15118
GATA2	ENCODE Transcription Factor Targets	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9597
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909079
Perturb_4387_KO_STAG2_SRP348449	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.5229
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950625
MIR222_KD_GDS4054_456_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.892
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22009
CAOV4	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02483
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43405
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834738
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.10705
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41318
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052882
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.495309
SNU182	DepMap CRISPR Gene Dependency	1.0	5.12096
mv1lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PD-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.964028
STK33_SKM	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6952-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU201	DepMap CRISPR Gene Dependency	1.0	3.31703
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.904
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0126
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907391
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1923
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42321
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.636785
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94556
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.82623
KURAMOCHI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6871
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883944
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883582
TASK1	DepMap CRISPR Gene Dependency	1.0	2.40461
SW1271	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999213
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8357
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95437
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HS729	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57301
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70D-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11632
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7115
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890556
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866991
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.52331
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25704
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56515
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13986
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.51454
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17588
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18269
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.7381
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.60458
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.88974
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	6.72409
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922852
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26968
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6923
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4603
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868422
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39268
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4928
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.49657
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.916881
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5558-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31791
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62527
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053561
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.2593
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	2.40252
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908077
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979209
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2571
Signal Transduction	Reactome Pathways 2014	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9487
ventrolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941123
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35627
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02699
Sarcoma_SARC_TCGA-DX-A8BP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870869
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06357
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.293
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.6651
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12123
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36348
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.98444
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20568
CAS1	DepMap CRISPR Gene Dependency	1.0	2.49726
POU3F2	ChEA Transcription Factor Targets	1.0	null
PMC11525193-41588_2024_1913_MOESM3_ESM.xlsx-ST12_Non_lead_PPI_0_9-Unnamed_16_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847434
Red cell distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.15229
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857803
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
ncih727	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21927
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2326
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31783
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.96222
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1334
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2915-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1271	CCLE Cell Line Gene CNV Profiles	1.0	2.25753
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08234
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.32166
HCC95	DepMap CRISPR Gene Dependency	1.0	2.17317
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4375
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952019
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929086
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85687
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38945
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
SNU407	CCLE Cell Line Gene CNV Profiles	1.0	1.61386
Prostate adenocarcinoma_PRAD_TCGA-HC-7742-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48537
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3531
FTC-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	79.407
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44656
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.926
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955023
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01522
496100482_PCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7079
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836839
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
SUDHL4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.64115
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21213
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02785
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR7-List_of_differentially_expressed_genes_in_AR11_vs_AR7_Negative_value_means_down-regulation_in_AR11_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00147
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5515-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.63871
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.88359
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863404
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7782
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71029
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7099-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01317
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0321
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68198
NCI-H820	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81838
Sensory Perception	Reactome Pathways 2024	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.956261
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47673
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42124
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.488
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53097
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24422
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76156
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905683
KMS20	DepMap CRISPR Gene Dependency	1.0	2.30932
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948979
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5652
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923921
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.96636
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93853
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18742
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5504
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29675
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38895
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28419
PMC11525193-41588_2024_1913_MOESM3_ESM.xlsx-ST12_Non_lead_PPI_0_9-Unnamed_10_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7373-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33277
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41085
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03948
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IRF1	ChEA Transcription Factor Targets	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07907
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903818
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847434
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2801
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21213
PCI-4B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02705
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.428
Prostate adenocarcinoma_PRAD_TCGA-G9-7521-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87J-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56879
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9163
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A266-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50758
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0931
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43335
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9038
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91241
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858044
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44746
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08409
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898553
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
496100493_TCx_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15581
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241438
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270561
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08869
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860989
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083554
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10918
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25257
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.3486
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9649
PC3	DepMap CRISPR Gene Dependency	1.0	4.79894
496100422_TCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0124
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
Adrenocortical carcinoma_ACC_TCGA-P6-A5OF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	1.36691
PANC-08-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828565
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
MEC1	DepMap CRISPR Gene Dependency	1.0	2.21262
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62283
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10506
GSE196117_1_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947429
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03742
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884001
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01082
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2696
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.10388
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6322
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06407
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4409
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.997489
chr1_247895453_A_G_b38	GTEx eQTL 2025	1.0	1.99184
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059367
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Blood-erythrocyte	Tabula Sapiens Gene-Cell Associations	1.0	1.37542
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7618
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42518
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881292
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14942
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19223
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5893-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881273
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841926
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06377
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8844
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824024
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49969
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977465
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847434
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.935325
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68986
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69693
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920949
signal transduction	GO Biological Process Annotations 2015	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0143
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881184
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.3467
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7825356-8844261.f3.docx-33-ZNF695_ZNF695	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93853
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
GATA1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08134
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13462
Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969776
Meconium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89525
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.9719
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3694
Follicular thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956709
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6858
SHI1	DepMap CRISPR Gene Dependency	1.0	4.52924
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847434
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3909
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3842
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4633
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34534
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07752
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3709
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9339
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25993
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25345
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Platelet alpha granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6373
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83222
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57608
Signaling by GPCR	Reactome Pathways 2014	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I8-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	1.0	1.45769
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3636
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923064
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833237
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11239
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35795
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118104
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.997465
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78511
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.3766
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92897
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926242
rituximab_homo sapiens_gpl570_gds3829	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4625
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5744
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4285
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.27282
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KASUMI1	DepMap CRISPR Gene Dependency	1.0	7.66401
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.0323
ONDA7	DepMap CRISPR Gene Dependency	1.0	3.33458
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1113
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83222
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2023	1.0	null
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00517
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25615
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.44704
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29347
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.373
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72195
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0382
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1041
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.24365
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76581
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05915
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.9827
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988629
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83175
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09008
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65061
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847434
JURKAT	DepMap CRISPR Gene Dependency	1.0	3.50571
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72655
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938644
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8729
biological regulation	GO Biological Process Annotations 2015	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17888
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.7417
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28181
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937166
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05432
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995322
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6603
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.28569
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
Nthy-ori 3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18194
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60249
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37109
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05157
PMC3708595-NIHMS474972-supplement-1.pdf-8-MYB_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59473
HCC202	CCLE Cell Line Gene CNV Profiles	1.0	1.483
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0365
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53346
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051128
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051538
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3022
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66308
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1669
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901898
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.732
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2156
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35923
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925085
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36455
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59809
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15427
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1315
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08851
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31301
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6185
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973812
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88789
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35111
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086126
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00763
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24179
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q0-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896468
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891327
Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-2.25464
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.682693
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.453
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01271
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TD-01A-51R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19133
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2017
GSE146247_0_v_1_sirt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Male infertility	WikiPathways Pathways 2024	1.0	null
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40268
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5622
Brain Lower Grade Glioma_LGG_TCGA-HT-7475-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.67069
KCL22	DepMap CRISPR Gene Dependency	1.0	5.19838
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.85
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9702
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16423
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30308
Lung squamous cell carcinoma_LUSC_TCGA-34-5236-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11246
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
Umbilical vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.22252
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94183
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18264
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.867804
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13046
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831046
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-42-ZBTB2_ZBTB2	Rummagene Transcription Factor Associations 2026	1.0	null
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52489
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26898
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901898
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.4192
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3855
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970138
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68831
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856786
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61842
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PEA1	DepMap CRISPR Gene Dependency	1.0	3.8383
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991771
SNU46	CCLE Cell Line Gene CNV Profiles	1.0	1.54484
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939992
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07533
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61W-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
LN235	DepMap CRISPR Gene Dependency	1.0	2.52246
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871882
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987733
Brain glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03989
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1761
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941563
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8993
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946793
PMC12956708-DataSheet1.xlsx-Supplementary_Table_6-Supplementary_Table_5_The_DEGs_from_sea_level_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.7479
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9805
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899589
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59643
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0552
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995421
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089598
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37577
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63876
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837516
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0554
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
GSE195559_3_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08384
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10469
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70572
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9723
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49826
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.75025
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9898
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86905
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GATA1	ChEA Transcription Factor Targets	1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4351
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00127
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2385
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NZOV9	DepMap CRISPR Gene Dependency	1.0	4.72128
GSE64642_0_v_1_sirt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5023
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0599
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08606
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4493
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85261
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	2.29076
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4607
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37577
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36446
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.666
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2208
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833837
MELHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4964
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984332
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30134
GATA2_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30562
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.75672
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.988
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34518
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993523
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.80987
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267102
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75632
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26398
Adenosquamous prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38895
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93624
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DW-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908883
ESCRT IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71118
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0216
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5330-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17839
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993759
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894576
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052758
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993759
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847434
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-KLF1_mod_KLF1	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936404
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.910555
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38617
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056941
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28497
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48987
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6411
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847434
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992369
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22559
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07038
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69518
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859447
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856821
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7668088__F9	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905563
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	114.995
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06498
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2446
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNFI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.86693
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45466
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28494
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12168
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75914
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71029
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.834332
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05809
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07034
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1033
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0292
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAOV-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45311
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11491
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12646
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25945
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055193
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051603
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.1859
Tea consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Skmes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
PMC11525193-41588_2024_1913_MOESM3_ESM.xlsx-ST12_Non_lead_PPI_0_9-Unnamed_13_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
e21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.48928
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43335
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7026
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3166
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85831
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88926
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923921
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18958
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32262
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11728
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72818
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929918
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978994
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870242
all	GWASdb SNP-Phenotype Associations	1.0	0.028994
Infertility, Male	HuGE Navigator Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2356
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56073
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.954357
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27182
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962317
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38028
KYSE270	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32607
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76015
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8845
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28418
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4481
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7411-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5757
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83083
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27881
BT474	CCLE Cell Line Gene CNV Profiles	1.0	2.59977
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12509
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4852-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7504
kidney	HPA Tissue Gene Expression Profiles	-1.0	-0.858363
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303919
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27067
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48831
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
SAM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989488
LP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51521
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94407
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870242
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HU-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5705
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91337
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056323
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05651
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6645
chr1_247857254_G_C_b38	GTEx eQTL 2025	1.0	1.561
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057311
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50426
SNU423	DepMap CRISPR Gene Dependency	1.0	2.36493
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24483
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84993
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8CQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144484_0_v_3_mllt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80562
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1888
HUNS1	DepMap CRISPR Gene Dependency	1.0	4.11255
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08538
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51704
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
Olfactory transduction	KEGG Pathways 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87669
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16423
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901898
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923921
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.188
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.981313
olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.990639
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.64154
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32231
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949308
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.972276
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872206
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05058
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5455
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99059
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.398
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45R-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.346
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949308
Large cell neuroendocrine carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6DY-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32064
azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0324
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15448
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96246
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4643
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00513
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995327
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984615
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923064
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05562
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.5052
GATA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24562
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28188
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974393
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14643
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48802
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.152
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5741
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835373
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.885062
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05471
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	3.53915
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07391
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5801
NCIH1975	DepMap CRISPR Gene Dependency	1.0	3.42577
18318837-TableS2	GeneSigDB Published Gene Signatures	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.839
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63679
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0581
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21562
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7386-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2861
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GJ-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894212
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.504
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0837
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.523
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39711
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.764741
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0413
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058634
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2712-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22691
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17312329-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860989
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9165
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872742
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935191
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10318
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60652
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889004
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5024
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-KLF1_mod_KLF1	Rummagene Transcription Factor Associations 2026	1.0	null
Bonemarrow	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05789
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631527
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1934
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832696
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5228
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995316
PMC7680901-Table_6.xlsx-both_up_GSE117165-SETBP1_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7973
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384013
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.794
Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1656
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46147
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90719
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A64Z-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63014
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51407
capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28213
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02675
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59437
496100557_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19996
Oligospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4444
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10679
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26262
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50449
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04792
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040093
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38383
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57725
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.39115
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11656
blood	GTEx Tissue Gene Expression Profiles	1.0	1.70861
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.0957
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68216
membrane part	GO Cellular Component Annotations 2015	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-0.858363
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79081
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867622
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CDKN2AIPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51918
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.664
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7102-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12287
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0415
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-176-HOXC10_HOXC10	Rummagene Transcription Factor Associations 2026	1.0	null
HT1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52023
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929012
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.904
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7256
BRAF_knockdown_193_GSE5481	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.81111
H3K9me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7990_KD_GPRC5C_ERP125638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.2041
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08027
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19738
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.731381
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7751
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87032
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
OACP4C	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57629
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925322
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.42124
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76015
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052881
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.988816
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09043
SET2	DepMap CRISPR Gene Dependency	1.0	8.39642
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943492
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.8285
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42753
icSARS CoV_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.601633
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43708
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.2338
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6825-01A-21R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08187
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882447
LIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8098
DHRS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14567
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	1.0	2.83017
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1533
PMC7339813-Supplementary_Data2.docx-51-ZNF883_ZNF883	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01271
MEL-HO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01305
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12772
NCI-H2009 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12696
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	1.22598
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082517
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37898
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06879
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.819
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29767
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056196
C4II	DepMap CRISPR Gene Dependency	1.0	3.09982
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829914
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15296
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32951
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98427
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901825
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7996
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
ACCMESO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61892
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CL-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7668088__F9	PFOCR Pathway Figure Associations 2024	1.0	null
MDA-MB-468	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956829
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30598
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04076
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24422
PMC11518656-ADHM-13-0-s002.pdf-86-EGR2_EGR2	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BU-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5403
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9767
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18612
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.65522
GSE144484_0_v_1_mllt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.12109
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B-CPAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00193
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75379
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.960056
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19212
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81298
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085312
biological_process	GO Biological Process Annotations 2015	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64402
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
Mean corpuscular hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7699
S-117	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RB1_KD_GSE50532_624_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29438
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
HBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7169
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.43956
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58363
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A5QV-01A-22R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38898
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.6899
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.85108
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05053
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09963
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063351
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YX-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15011
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52396
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33103
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VR-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947034
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Blood metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.50458
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901898
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51735
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.412199
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868936
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.15
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7427-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11438
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8965
Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1707
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
Prostate adenocarcinoma_PRAD_TCGA-EJ-7318-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.907
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51211
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997641
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6947
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RO-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243918
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846804
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5115-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38987
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6208
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05688
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924442
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25198
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71029
Lung squamous cell carcinoma_LUSC_TCGA-21-1077-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECGI10	DepMap CRISPR Gene Dependency	1.0	2.23612
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63857
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3544
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17236
SW48	DepMap CRISPR Gene Dependency	1.0	2.64249
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5918
HS821T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94554
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.55356
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31072
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2329
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11446
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45T-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08373
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.45744
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.726
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19316
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21226
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6515-01A-21R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61363
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81973
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.39953
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865538
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.56135
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12765
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875294
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06397
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02705
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055999
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7268
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5369-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0196
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999213
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05131
KGN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.997288
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.73325
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71543
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968064
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04484
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6535
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11482
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.933527
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U2904	DepMap CRISPR Gene Dependency	1.0	2.08905
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31932
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88955
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19906
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.55957
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.742976
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.656
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56569
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3778
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85898
LN382	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56237
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44088
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MM1S	DepMap CRISPR Gene Dependency	1.0	2.63151
Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IJ-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7263
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
Reticulocyte fraction of red cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6699
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13077
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0382
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112953
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05688
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39844
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38767
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73814
FOXA2	ENCODE Transcription Factor Targets	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9944
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847424
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.7416
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21073
DPAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16035
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93349
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70768
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.885569
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1727
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884008
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7133
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50J-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053014
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.941332
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06808
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20953
Azoospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903289
LS	DepMap CRISPR Gene Dependency	1.0	2.36882
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986129
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848749
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894212
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19133
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A69P-06A-21R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DEL	CCLE Cell Line Gene CNV Profiles	1.0	1.9906
HDQ-P1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11433
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.3646
KYSE520	DepMap CRISPR Gene Dependency	1.0	4.45029
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	6.53904
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34382
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.918635
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0763
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8569
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0295
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U251MG	DepMap CRISPR Gene Dependency	1.0	3.50535
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68494
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057005
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00555
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22178
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.47408
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07496
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8011
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30129
Prostate adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21204
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83926
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
HSC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68324
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.3236
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60931
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900971
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cis-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.8695
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33078
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205163,GSE205164_3_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0579
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.981377
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06846
pb88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.019
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.847889
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mean platelet volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.9699
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TARDBP_02_80	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58658
RNF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57431
CH157MN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63066
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979179
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.651
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90954
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955155
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05637
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.01736
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4877
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.90594
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
M07E	DepMap CRISPR Gene Dependency	1.0	4.91211
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.8862
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05074
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
KMS27	DepMap CRISPR Gene Dependency	1.0	2.69123
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.9187
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
SNU1105	DepMap CRISPR Gene Dependency	1.0	3.17892
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99731
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894533
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6121
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57057
Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2955
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2025	1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0352
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.995
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	1.61307
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KON	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	1.0	1.7551
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835006
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07371
OPM2	CCLE Cell Line Gene CNV Profiles	1.0	1.68228
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13586
Perturb_15802_KD_METTL3_SRP373116	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5035
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82626
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.415773
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952019
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1146
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.758
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928854