association	dataset	threshold value	standardized value
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7388-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17539
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
NCIH838	Achilles Cell Line Gene Essentiality Profiles	1.0	1.6003
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23278
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07224
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33541
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
786O	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04559
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	1.4369
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863502
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5389
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68582
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-1.01384
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18328
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.67577
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.185
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06962
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44717
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15717
DBTRG05MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.38787
OAZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98409
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.668211
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COL18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68596
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.464
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7833
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37094
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77795
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42179
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.998637
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44734
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09194
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.459
SAP30	ENCODE Transcription Factor Targets	1.0	null
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2992
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory perception	GO Biological Process Annotations 2015	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.964723
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
CORL88	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00365
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3027
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46071
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73913
Lymph_Node-innate lymphoid cell	Tabula Sapiens Gene-Cell Associations	1.0	0.342146
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2087
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	2.25908
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0835
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19069
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6342-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.04453
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0157
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1779
CAKI1	CCLE Cell Line Gene CNV Profiles	1.0	1.57399
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100661_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39338
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15226
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.736861
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TOP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35777
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04054
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70314
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive congenital ichthyosis 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Lymph_Node-cd4-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.87099
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RASSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03654
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32589
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89274
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.50892
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24036
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72317
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96508
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31935
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48691
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05165
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2171	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05197
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47385
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7639
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77485
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35106
PAQR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13585
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88077
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57896
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05967
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17868
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950858
NFATC3_01_166	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59366
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18676
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58853
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77803
Blood-cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	4.58893
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8506
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1701
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40769
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21958
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23454
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11266694-41698_2024_651_MOESM1_ESM.pdf-2-ZNF469_ZNF469	Rummagene Transcription Factor Associations 2026	1.0	null
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21074
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93461
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	2.21657
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04317
single-organism process	GO Biological Process Annotations 2015	1.0	null
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944168
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00911
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0657
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05032
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64525
REST	ChEA Transcription Factor Targets	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.991699
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.01384
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0162
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.375
FU97	DepMap CRISPR Gene Dependency	1.0	2.73901
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74304
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34724
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.42341
Brain Lower Grade Glioma_LGG_TCGA-HT-7689-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7774
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49628
EGI1	DepMap CRISPR Gene Dependency	1.0	2.25791
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47429
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889604
CREBZF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21609
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55624
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889885
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	3.20107
Brain Lower Grade Glioma_LGG_TCGA-W9-A837-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7100-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0104
PLD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32517
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06962
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12623
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36654
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1705
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	2.62766
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01504
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58469
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29306
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944168
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08607
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.63222
k1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3961
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72051
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39326
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.12604
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79289
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17041
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51244
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2505
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2626
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33872
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02011
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9618
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87484
Olfactory transduction	KEGG Pathways 2026	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06432
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0253
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7547
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23789
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
Salivary_Gland-cd4-positive helper t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.02163
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33987
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16149
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979325
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1105	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.51547
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97788
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.849876
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8145-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	2.24157
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62697
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02014
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57614
HKA1	DepMap CRISPR Gene Dependency	1.0	3.02778
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5939
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27446
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9274
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
WM983B	DepMap CRISPR Gene Dependency	1.0	2.94061
SCC4	DepMap CRISPR Gene Dependency	1.0	2.38405
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77547
BRI3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59069
GYPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32851
GSE233679_12_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09255
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5392
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51518
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81442
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8002
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22136
RSV-A2_24Hour-KO_RSV_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.11719
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22011
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69185
KP2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01605
SUV39H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85478
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943236
HICS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7918
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.140749
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02117
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45716
HT1197	CCLE Cell Line Gene Expression Profiles	1.0	1.56546
ZNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41481
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24141
YUHOIN0650	DepMap CRISPR Gene Dependency	1.0	4.24663
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00306
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89823
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41327
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20678
FLI1	ChEA Transcription Factor Targets	1.0	null
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0336
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7552
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56692
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23449
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.29277
SMAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87791
SKGIIIA	DepMap CRISPR Gene Dependency	1.0	3.26823
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.0044
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34279
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.823975
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.40685
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7377
Bonemarrow	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.940986
ZNF143	ENCODE Transcription Factor Targets	1.0	null
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	1.38806
MAFK_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12311
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.03988
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42311
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3436
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35422
ADAMTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64456
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0427
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41557
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83576
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19056
YAPC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76718
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69029
UOK101	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.03661
GATA3	ENCODE Transcription Factor Targets	1.0	null
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32921
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86271
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06701
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89918
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67025
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60628
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850052
membrane	GO Cellular Component Annotations 2015	1.0	null
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45807
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7226
CAPAN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48287
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29784
SHMAC5	DepMap CRISPR Gene Dependency	1.0	2.07248
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90473
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.576
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G6-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19813
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.47536
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8006
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29545
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45716
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34655
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0814
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1047
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2357
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.267
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.78376
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42568
CREB1	ENCODE Transcription Factor Targets	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18126
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
BMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44319
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44875
Prostate adenocarcinoma_PRAD_TCGA-CH-5771-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7955
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3361
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13458
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV362	CCLE Cell Line Gene Expression Profiles	1.0	1.7742
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1847
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1472
A253	DepMap CRISPR Gene Dependency	1.0	2.46602
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2739
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4508
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34555
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88989
NMCG1	DepMap CRISPR Gene Dependency	1.0	4.55403
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36168
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5805
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67571
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79128
cellular_component	GO Cellular Component Annotations 2015	1.0	null
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2359
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.29481
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944168
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825093
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64006
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7738
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23299
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1551
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02713
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68864
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1709
SNU685	CCLE Cell Line Gene CNV Profiles	1.0	1.63469
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36387
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7492
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09474
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35851
DAOY	CCLE Cell Line Gene Expression Profiles	1.0	1.9159
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78624
Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11954
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58331
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2716
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32581
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HI-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9111
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	2.04466
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HE-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29829
Lung adenocarcinoma_LUAD_TCGA-95-8039-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9989
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5405
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
SAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895641
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920257
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81249
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77914
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1794
D-247MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCHY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72165
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1231
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.73
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4405
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
HSC-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53765
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61743
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890657
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35015
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
SNU61	DepMap CRISPR Gene Dependency	1.0	2.78639
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9298
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30878
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00911
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859769
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16578
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40147
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12833
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35272
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03441
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47616
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53603
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84132
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4441
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53422
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.854507
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16959
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6010-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40767
SW480	CCLE Cell Line Gene Expression Profiles	-1.0	-2.91459
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.559
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63618
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84021
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78972
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6774
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03843
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
Klippel-Feil syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829288
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03921
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6605
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91713
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20654
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.53
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05032
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28593
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2076
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933199
Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nthy-ori 3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
CDKN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18954
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.81081
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894464
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05929
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35466
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.6378
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40465
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47689
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1554
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13381
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64125
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61383
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	2.87884
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32897
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50511
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74538
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FTC-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58853
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929707
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47244
PMC11358472-41467_2024_51851_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_4_gene_expression_levels_for_323_genes_connected_to_EWS-WT1_in_JN-DSRCT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83817
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1032
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	2.35243
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11745
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57479
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14179
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NE-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.837
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1934
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23949
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04935
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17758
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33351
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2738
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887003
YD8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62665
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymus-dn3 thymocyte	Tabula Sapiens Gene-Cell Associations	1.0	4.16425
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4564
Lung adenocarcinoma_LUAD_TCGA-69-8453-01A-12R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59927
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.54522
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5348
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17985
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1341	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71109
Lung adenocarcinoma_LUAD_TCGA-62-8402-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.865857
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27883
Lung adenocarcinoma_LUAD_TCGA-97-8175-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63001
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36919
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.44566
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2318
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2735
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
SCC-25	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15125
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17868
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.971955
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34673
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1458
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27299
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9975
CADM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44047
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25639
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5902
KYM1	DepMap CRISPR Gene Dependency	1.0	3.30047
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957829
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.937798
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MQ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863502
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41549
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22626
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	2.01906
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903727
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17046
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983813
SPATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04915
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98682
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.71467
HEC59	CCLE Cell Line Gene Expression Profiles	1.0	1.35726
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943681
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7481
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12843
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9698
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLR25	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66939
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7344
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14922
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.446
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38681
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS513	CCLE Cell Line Gene Expression Profiles	1.0	2.17224
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0349
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8347
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944168
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2911
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53646
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	1.42861
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7013
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.222
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1061
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
TDRD3-21172665-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Setleis syndrome_Skin fibroblast_GSE16524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.958172
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95839
ADD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73701
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51333
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.977433
Clove	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63289
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
SUSA	DepMap CRISPR Gene Dependency	1.0	2.37272
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30907
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32026
SAOS2	DepMap CRISPR Gene Dependency	1.0	2.03074
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90405
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.923
PMC10679662-mmc3.xlsx-NC-D3-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
Senior-Loken syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71059
MKN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34633
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75134
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49188
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34114
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66043
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.746
RCOR3	ChEA Transcription Factor Targets	1.0	null
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0659
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.823975
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
MXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27723
KYSE450	DepMap CRISPR Gene Dependency	1.0	2.13476
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831774
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49C-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1079	DepMap CRISPR Gene Dependency	1.0	3.52176
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24249
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863502
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20566
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.823975
signal transduction	GO Biological Process Annotations 2015	1.0	null
FAM8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87953
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44432
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47137
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50984
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1538
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835559
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94809
HS751T	CCLE Cell Line Gene Expression Profiles	1.0	1.89202
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14504
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23619
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888709
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6775
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10291
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878123
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46391
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
HT3	DepMap CRISPR Gene Dependency	1.0	2.84967
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.316
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32026
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01037
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31615
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42179
ACTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59903
PHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.267
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.46157
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29215
response to stimulus	GO Biological Process Annotations 2015	1.0	null
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74739
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5527
2313287	DepMap CRISPR Gene Dependency	1.0	2.82626
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894464
SIMA	CCLE Cell Line Gene CNV Profiles	1.0	1.39412
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6883
TMEM104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94861
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72402
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.98929
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05865
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.54713
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896657
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.491704
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
LOUCY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46247
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55953
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944168
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.0178
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5072
P3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1853
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32203
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48925
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00239
KASUMI1	CCLE Cell Line Gene Expression Profiles	1.0	1.58466
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHL1DM	DepMap CRISPR Gene Dependency	1.0	2.29219
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.01384
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.3008
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9012
HCC2814	Achilles Cell Line Gene Essentiality Profiles	1.0	2.76858
ST486	CCLE Cell Line Gene Expression Profiles	1.0	1.50111
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15135
Cecum cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.12939
GSE145249_0_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46526
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03407
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3845
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1898
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6719
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Signaling by GPCR	Reactome Pathways 2014	1.0	null
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.23013
NUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32777
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4266
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39933
MKN45	DepMap CRISPR Gene Dependency	1.0	3.44915
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69478
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3357
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
PSMB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7255
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4275
AGS	CCLE Cell Line Gene Expression Profiles	1.0	1.5216
C8orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77473
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.71884
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88463
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5905
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8709
Prostate adenocarcinoma_PRAD_TCGA-CH-5738-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2634
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30496
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09836
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19056
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8991
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R4-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3333
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS19BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76854
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970453
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1181
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-3.5264
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.905564
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80709
ZR-75-30	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64463
Blood-cd8-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.257211
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17868
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.978354
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3182
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.8121
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0885
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17224
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11448
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38263
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19889
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863502
OPM2	DepMap CRISPR Gene Dependency	1.0	2.46472
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79501
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Donnai-Barrow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO792	CCLE Cell Line Gene Expression Profiles	1.0	1.57579
Lung adenocarcinoma_LUAD_TCGA-50-5941-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943681
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.81215
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05036
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10727
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	2.60069
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827149
OCIMY5	DepMap CRISPR Gene Dependency	1.0	3.91766
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8364
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7874
ABITRAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36638
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAC2A	DepMap CRISPR Gene Dependency	1.0	2.36549
KPNYN	DepMap CRISPR Gene Dependency	1.0	3.43384
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
COV504	CCLE Cell Line Gene CNV Profiles	1.0	1.54073
Brain Lower Grade Glioma_LGG_TCGA-HT-7601-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2947
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43739
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29567
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91786
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.603785
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.0191
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.237401
A172	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12981
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
EGR1	ENCODE Transcription Factor Targets	1.0	null
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
NAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92782
GATA1	ChEA Transcription Factor Targets	1.0	null
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9469
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62891
ZNF701	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63261
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2409
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72022
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08766
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08685
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.291787
MM370	DepMap CRISPR Gene Dependency	1.0	2.81245
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41699
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.0799
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9921
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.849896
SNU475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3708
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53066
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96946
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8286
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040382
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.5744
Brain Lower Grade Glioma_LGG_TCGA-DU-5849-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FP-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87307
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70678
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	1.82433
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1896
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5428
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959216
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7286
TAL1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.302
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890474
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFRSF10D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46858
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77427
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46976
SIN3B	ChEA Transcription Factor Targets	1.0	null
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5308
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896657
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4271
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842971
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07334
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935218
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16583
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
IGR37	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4886
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95107
FGFR1OP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84381
ZNF256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54893
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7478
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58066
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.46009
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.020485
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27222
SF126	DepMap CRISPR Gene Dependency	1.0	5.07438
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7401-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45256
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2255
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28075
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9304
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97073
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94947
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31636
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2488
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9164
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07118
G protein-coupled receptor homodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.489
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHP126	CCLE Cell Line Gene CNV Profiles	1.0	1.75376
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22942
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.96048
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73707
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22408
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1762
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53731
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7765
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26086
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8924
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13817
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82427
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83496
FHOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37771
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50759
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5926
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8276
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59896
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834729
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.25
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77459
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2015
RERFGC1B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74175
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92469
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42523
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06453
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
CAL29	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47719
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9826
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53453
Lung adenocarcinoma_LUAD_TCGA-49-6744-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72703
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47616
membrane part	GO Cellular Component Annotations 2015	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33954
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30918
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_01_164	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59839
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9374
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARHGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37029
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25683
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.6798
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.23932
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
Spleen-naive thymus-derived cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.512017
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6969
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13458
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48585
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67266
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05165
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	3.26445
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01364
Signal Transduction	Reactome Pathways 2014	1.0	null
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.876939
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32608
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7079
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2329
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.43127
ZNF100_01_124	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60988
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23871
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
HSD3B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27286
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12833
CEP131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24867
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863502
496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45087
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18705
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11576
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59878
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12833
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.488
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39453
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2495
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95307
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.95269
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RB-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
U87MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0652
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8667
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1169
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870565
MAF_01_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58903
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2414
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26383
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77589
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55711
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23083
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2429
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A180-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22959
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34249
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99844
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23107
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0464
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60382
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6258
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827149
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37152
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68669
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49942
RERFLCAI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92867
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51328
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4642
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00805
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08403
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47017
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43866
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22819
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23512
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35307
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52313
SLR24	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00899
Prostate adenocarcinoma_PRAD_TCGA-HC-7742-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53214
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88645
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863986
COV504	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.40531
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.01384
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.291787
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864815
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05339
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890474
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
CAOV3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.41284
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92748
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
PEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75753
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33901
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14224
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10533
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22726
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77485
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08607
Blood-cd4-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0825318
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93762
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2657-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8655
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77718
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8105
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8505
biological_process	GO Biological Process Annotations 2015	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5012
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.49827
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29235
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936654
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43145
C19orf84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00858
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87836
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15831
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73172
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55735
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53723
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46303
SNU626	CCLE Cell Line Gene Expression Profiles	1.0	1.67241
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31397
GSE180468_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0834
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11053
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0245
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00403
HS343T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58185
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0422
EP300	ENCODE Transcription Factor Targets	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863502
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2314
MERO48A	DepMap CRISPR Gene Dependency	1.0	2.12076
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.64166
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23333
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07276
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58555
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58727
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43203
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63428
NCI-H716 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22264
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12321
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.897099
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29356
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33564
RUNX-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.4905
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7028
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42573
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96098
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NHEK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15684
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42594
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979325
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61879
Portio vaginalis cervicis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
TE1	DepMap CRISPR Gene Dependency	1.0	2.0888
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.33328
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45716
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92927
HSC2	DepMap CRISPR Gene Dependency	1.0	2.97705
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0567
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79696
SUV39H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35853
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.929978
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.2111
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84866
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58298
Prostate adenocarcinoma_PRAD_TCGA-HC-7231-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24505
ftc238	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3038
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9426
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78853
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01738
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-14_CD7_CD1a-_L-IC_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3022
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U2OS	CCLE Cell Line Gene CNV Profiles	1.0	1.57947
C10	DepMap CRISPR Gene Dependency	1.0	2.06355
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878123
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872229
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6282
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39252
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35851
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834729
PRR14L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
TE9	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32785
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
NUDT21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80526
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52986
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2744
RMG-I	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863502
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7075
neurological system process	GO Biological Process Annotations 2015	1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5911
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30218
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16929
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73556
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21547
RCC-JW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A86F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1188
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27973
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5233
SNU16	DepMap CRISPR Gene Dependency	1.0	2.43072
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vastus lateralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
VPS52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0079
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835559
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3924
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67D-01A-31R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55539
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46681
SKG-IIIA	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	ChEA Transcription Factor Targets	1.0	null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10S-01A-22R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.518
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27069
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.105834
HCC2935	DepMap CRISPR Gene Dependency	1.0	3.45855
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42339
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043275
Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-2.88365
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPL1	CCLE Cell Line Gene CNV Profiles	1.0	1.84093
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.80364
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17985
receptor activity	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7634-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1921
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3725
ARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82131
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06151
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06453
RMUGS	DepMap CRISPR Gene Dependency	1.0	3.37667
PJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22983
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040178
COV434	CCLE Cell Line Gene Expression Profiles	1.0	2.0227
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.5111
CHD2	ENCODE Transcription Factor Targets	1.0	null
LC1SQSF	CCLE Cell Line Gene Expression Profiles	1.0	1.43343
A673	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57262
Prostate adenocarcinoma_PRAD_TCGA-HC-7818-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8656035-40001_2021_613_MOESM2_ESM.docx-34-FOXN1_FOXN1	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827149
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37955
COLO818	CCLE Cell Line Gene Expression Profiles	1.0	1.72551
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.513
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48496
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61584
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90473
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.804
A2058	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23832
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02014
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28259
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DBNDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19493
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4737
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13641
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0512
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67575
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2266
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.533
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9638
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42741
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9559
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV_12Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.3553
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2111
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2414
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GN-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39215
BT20	Achilles Cell Line Gene Essentiality Profiles	1.0	1.5361
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05108
KURAMOCHI	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14444
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07234
PRKACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78584
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10395
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0581
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09801
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30338
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928834
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11576
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TC106	DepMap CRISPR Gene Dependency	1.0	2.08701
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66598
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7869
CP66-MEL	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
BT-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SJSA1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63098
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06354
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1273
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943236
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2851
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1464
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28552
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00319
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
MYC	ENCODE Transcription Factor Targets	1.0	null
CEP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12064
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41001
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7924
A253	CCLE Cell Line Gene Expression Profiles	1.0	1.51784
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.903
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
biological regulation	GO Biological Process Annotations 2015	1.0	null
SLC45A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70849
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8889
BL70	DepMap CRISPR Gene Dependency	1.0	2.30831
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8376
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74285
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91268
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55177
IMR32	CCLE Cell Line Gene CNV Profiles	1.0	1.77428
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8998
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.165
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09255
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JT-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58096
SKRC20	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.46146
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50904
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1923
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76378
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4663
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1333
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2248
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35684
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2619
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01824
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17868
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06531
TFAP2A	ChEA Transcription Factor Targets	1.0	null
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98002
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4783
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.887219
NCIH2110	CCLE Cell Line Gene Expression Profiles	1.0	2.55783
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08607
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55354
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37631
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94933
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3838
HARA	DepMap CRISPR Gene Dependency	1.0	3.06693
MAFK	ENCODE Transcription Factor Targets	1.0	null
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83305
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.970558
Adrenocortical carcinoma_ACC_TCGA-OR-A5LR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXK2_02_31	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62149
NCIH2172	CCLE Cell Line Gene Expression Profiles	1.0	1.9483
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27133
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32845
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.975004
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Intestinal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HA-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH4	DepMap CRISPR Gene Dependency	1.0	2.6066
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4491
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
K562	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11229
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16319
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64114
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2488
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1215
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4167
TEX45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47651
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10933
LCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57418
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COGN278	DepMap CRISPR Gene Dependency	1.0	3.19837
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60835
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0248
RCM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33199
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86489
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39407
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35469
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.74031
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23988
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF708_01_130	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.89095
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47116
Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1632
HT29	DepMap CRISPR Gene Dependency	1.0	3.05867
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27956
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47244
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68468
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8638
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65873
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCNB1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24763
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16784
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PA1	DepMap CRISPR Gene Dependency	1.0	2.74593
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61347
Lymph_Node-naive thymus-derived cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	2.63541
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4952
PATU8988S	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4639
HS852T	DepMap CRISPR Gene Dependency	1.0	2.03183
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30818
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCF12	ENCODE Transcription Factor Targets	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20796
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PCTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37199
Prostate adenocarcinoma_PRAD_TCGA-HC-A631-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296