association	dataset	threshold value	standardized value
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.4822
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.128752
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.4461
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.17575
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82433
ZNF839	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6601
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19315
KPL1	CCLE Cell Line Gene CNV Profiles	1.0	1.84093
Brain Lower Grade Glioma_LGG_TCGA-DU-8166-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8995
KKU100	DepMap CRISPR Gene Dependency	1.0	2.76311
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10606
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41895
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.83306
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12249
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2115
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11032
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.92036
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13238
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49776
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976411
RMG-I	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
A549	DepMap CRISPR Gene Dependency	1.0	2.6959
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83135
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43313
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.75826
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7219
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23122
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6299
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08196
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6213
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2972
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.01497
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76985
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95255
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14275
Prostate adenocarcinoma_PRAD_TCGA-CH-5765-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1161
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-1.17459
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	3.81119
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18394
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13339
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8123
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8494
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88386
HT144	DepMap CRISPR Gene Dependency	1.0	2.38013
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13011
C8166	DepMap CRISPR Gene Dependency	1.0	2.15834
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82431
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	2.12029
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	2.35243
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.14866
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32398
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.0337
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18394
GALK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31622
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7169
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01401
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1227
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4051
GP5D	DepMap CRISPR Gene Dependency	1.0	3.2621
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6944
NR2F2_01_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.9677
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866043
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65181
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9403
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826989
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.819
MYC	ENCODE Transcription Factor Targets	1.0	null
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.63222
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13672
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882452
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4029819-pone.0098069.s006.xlsx-Sheet1-Table_S5_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_metastases_p-value_0_01_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9382
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.694
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38003
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02846
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0612
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18861
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.68081
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.5038
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37914
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44635
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23438
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02406
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.99956
HT3	DepMap CRISPR Gene Dependency	1.0	2.65793
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.916403
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MUTZ8	DepMap CRISPR Gene Dependency	1.0	3.403
H413	DepMap CRISPR Gene Dependency	1.0	2.10469
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49608
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2292
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19589
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18281
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04748
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876814
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.58599
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.781
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78612
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00752
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857912
Signaling by GPCR	Reactome Pathways 2014	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SW1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21219
HCC1937	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3477
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.943
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3933
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827856
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.2048
Brain Lower Grade Glioma_LGG_TCGA-DU-6401-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21844
mRNA_DPPA5A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91583
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATAD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45112
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.34694
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4852-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4171
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56017
postcentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866789
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02512
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6915
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.2431
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840441
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4516
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21668
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.713352
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67467
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5881
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67298
CP66-MEL	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.949156
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45807
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02168
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.47468
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917741
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844586
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5022
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870447
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13339
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49182
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948456
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2188
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7718
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903315
HMGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64025
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72444
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2721
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
RAB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54239
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28256
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C32	DepMap CRISPR Gene Dependency	1.0	2.12085
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56888
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32561
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17331
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8289
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.30586
TXNDC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42981
SNU685	CCLE Cell Line Gene CNV Profiles	1.0	1.63469
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6884
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5553
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9329
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0837
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867684
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
MCF7	DepMap CRISPR Gene Dependency	1.0	3.88165
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00366
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20579
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10716
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04443
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.9474
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2541
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC4	DepMap CRISPR Gene Dependency	1.0	2.67107
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.993403
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9014
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30301
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09983
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.791496
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837225
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52389
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.894418
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71048
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2666
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07343
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.907277
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51073
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57952
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825289
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0527
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13928
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36402
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69329
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9898
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07831
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18394
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835002
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.46009
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	2.01906
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28765
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915312
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.852
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911171
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935142
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0582
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87709
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57186
RBCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33605
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.08922
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
MC-CAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88381
TTC642	DepMap CRISPR Gene Dependency	1.0	3.73112
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9526
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39904
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.643
planum polare, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852437
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947522
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.46332
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967961
HN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32191
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2561
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20596
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MIR222_KD_GDS4054_456_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939758
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26968
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62422
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06821
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32401
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	3.59519
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55933
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
RERFLCAI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92855
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29932
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28043
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81711
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP212	DepMap CRISPR Gene Dependency	1.0	2.31076
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81406
membrane	GO Cellular Component Annotations 2015	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.58648
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1506
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948456
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964703
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55864
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5252
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.23293
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20796
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01128
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70673
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34991
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893802
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0158
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
EP300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9591
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HD-01B-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
CAKI1	CCLE Cell Line Gene CNV Profiles	1.0	1.57399
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6696
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65407
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4alpha_DEPLETION_GDS4798_91_human_HepG2 hepatocellular carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.958779
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.50892
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2486
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842608
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	2.21657
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0514
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.2648
Olfactory transduction	KEGG Pathways 2026	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70991
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3515
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8157
496100342_PCx_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01974
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910406
496100669_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79531
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966711
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22462
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9885
ZSCAN26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11785
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825289
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837225
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06593
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29127
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46154
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9133
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04887
PSN1	DepMap CRISPR Gene Dependency	1.0	2.26913
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49648
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
MKN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32903
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36832
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3919509-NIHMS471461-supplement-3.xls-Table_S1-ZNF33A_ZNF33A	Rummagene Transcription Factor Associations 2026	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22333
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9174
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914681
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.081
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.8554
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9527
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17287
SNU475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35275
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948456
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30657
PATU8988S	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44088
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.71884
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83899
SPIB	JASPAR Predicted Transcription Factor Targets	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0061
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.988227
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.66444
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.41992
AKT1_knockout_214_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44178
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854097
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840441
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11743
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861844
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0563
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9104
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962768
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN464	DepMap CRISPR Gene Dependency	1.0	2.01133
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81101
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894671
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8353
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36901
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3985
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.25299
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863508
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM983B	DepMap CRISPR Gene Dependency	1.0	2.96938
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1532
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16179
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8558
MCIDAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48644
membrane part	GO Cellular Component Annotations 2015	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867684
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6161
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13672
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1766
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37331
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77409
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90896
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29187
ZFP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14469
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991882
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1293
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2839
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRY	JASPAR Predicted Transcription Factor Targets	1.0	null
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.47898
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24767
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832437
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32661
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33827
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04908
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2701
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896765
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.37115
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90896
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1534
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.93507
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44539
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0667
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17494
NOTCH_INHIBITION_GDS2794_61_human_MOLT4 (T-cell acute lymphoblast leukemia) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00667
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.14316
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.5015
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894671
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18917
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887869
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9467
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1079
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836683
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2541
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.31158
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2788
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11504
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.304
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06608
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896783
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BICR16	DepMap CRISPR Gene Dependency	1.0	2.27637
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07209
Sarcoma_SARC_TCGA-IE-A6BZ-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47544
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02972
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5444
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.95813
BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980303
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67736
Kidney Chromophobe_KICH_TCGA-KM-8442-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27265
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867684
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.17459
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57521
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35294
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892327
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899128
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11494
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80096
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.17342
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948456
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5824
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10772
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0638
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.2419
Brain Lower Grade Glioma_LGG_TCGA-HT-7858-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49648
HNF4A_KD_GDS4798_550_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PCI-4B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.44566
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950458
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6869-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8514
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	94.2998
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80601
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65296
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1676
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.575
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58215
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
DENND4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95117
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912989
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.57706
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
Signal Transduction	Reactome Pathways 2014	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59853
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837225
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09543
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.40685
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904577
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61569
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90385
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3574
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V3-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0554
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07209
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867684
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8751
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.962705
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878054
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.50513
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52851
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75907
IMR32	CCLE Cell Line Gene CNV Profiles	1.0	1.77428
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7969
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5862
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839725
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57537
CDCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2292
COV504	CCLE Cell Line Gene CNV Profiles	1.0	1.54073
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38704
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21914
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48643
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83396
VDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73972
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2988
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914681
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
PANC0203	DepMap CRISPR Gene Dependency	1.0	3.01323
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72926
signal transduction	GO Biological Process Annotations 2015	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6989
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.81215
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4468
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99277
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06921
Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3918
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867351
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4101-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.959171
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25883
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69108
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12525
Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7907
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67626
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24411
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40122
CD83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7158
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59853
Sensory Perception	Reactome Pathways 2024	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.59857
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01773
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92736
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11091
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.719642
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8072-01A-31R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1278
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8331
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08333
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06531
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859588
TYMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68373
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.57951
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2621
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.833571
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9475
SKPNDW	DepMap CRISPR Gene Dependency	1.0	2.41265
NCIH3122	DepMap CRISPR Gene Dependency	1.0	3.70074
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06943
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46486
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95805
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87293
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36528
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880269
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9329
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65093
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61746
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18394
CTV1DM	DepMap CRISPR Gene Dependency	1.0	3.14106
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8113
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.4557
MKN45	DepMap CRISPR Gene Dependency	1.0	2.0861
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4414
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90326
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08695
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33166
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51854
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.841774
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9929
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838893
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79688
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32661
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9522
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80532
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7579
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6182
ZNF570	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58983
TC106	DepMap CRISPR Gene Dependency	1.0	4.06672
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22601
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57167
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.753582
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28765
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948456
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1801
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07498
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28361
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47651
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1887
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46616
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9375
C99	DepMap CRISPR Gene Dependency	1.0	2.56996
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1073
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873167
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.56624
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C80	DepMap CRISPR Gene Dependency	1.0	3.18397
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4349
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16721
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911171
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35068
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88468
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89443
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.75279
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.855836
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8486
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.399
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42149
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.60349
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8349
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840441
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
TRIM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6881
G-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFE319	DepMap CRISPR Gene Dependency	1.0	2.56341
UOK101	DepMap CRISPR Gene Dependency	1.0	3.97085
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55688
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JAK2_activemutant_178_GSE44961	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.60248
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1189
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62472
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04517
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25471
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02378
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6545
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.8965
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8555
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90987
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1609
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.996386
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6085
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08343
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02715
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927777
SKG-IIIA	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
HNF4A_KD_GSE29084_694_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPECC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73963
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15255
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.152
Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11743
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1666
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97193
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15748
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89667
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.4177
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52685
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IZ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2461
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38576
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.853797
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891198
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867684
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52785
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910147
Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53_01_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.56131
CAPAN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4588
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1683
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03447
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15392
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.987165
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.152
Dystocia	CTD Gene-Disease Associations	1.0	1.01437
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13109
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14359
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07855
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34003
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
ZNF248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61044
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.01082
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CHP126	CCLE Cell Line Gene CNV Profiles	1.0	1.75376
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24684
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.984281
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22077
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32751
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04144
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25471
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59726
PCGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90308
JTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84568
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40556
DEL	DepMap CRISPR Gene Dependency	1.0	2.79433
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74386
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867684
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12742
OE21	DepMap CRISPR Gene Dependency	1.0	2.0576
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6839
U2OS	CCLE Cell Line Gene CNV Profiles	1.0	1.57947
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18291
STAT1	ChEA Transcription Factor Targets	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03254
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.8764
PMC3607232-mmc3.xlsx-RUNX1_targets_in_K562_and_SEM-x_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973465
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
COLO201	DepMap CRISPR Gene Dependency	1.0	3.20646
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55584
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0741
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.6091
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31613
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2199
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.5832
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57343
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29522
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08812
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4753
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11032
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03709
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8597
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17331
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.64153
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52575
SW48	DepMap CRISPR Gene Dependency	1.0	2.2698
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59366
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6619
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_10_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7244
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3362
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.950837
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0146
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.302
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843269
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828962
SNU61	DepMap CRISPR Gene Dependency	1.0	2.35032
496100511_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.43892
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
COLO792	DepMap CRISPR Gene Dependency	1.0	2.96907
MEL270	DepMap CRISPR Gene Dependency	1.0	2.51986
HDAC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1341
MHHNB11	DepMap CRISPR Gene Dependency	1.0	3.08016
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13339
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1832
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859123
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22138
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5886
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0556
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26442
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18284
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
MRTFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94999
RCOR1	ChEA Transcription Factor Targets	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.945684
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.45484
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5909
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847656
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864539
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.437563
biological_process	GO Biological Process Annotations 2015	1.0	null
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	1.4369
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.94248
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.00082
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96411
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2891-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866104
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.40705
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.86
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7281
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.84663
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92524
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0648
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2489
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	1.82433
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.843543
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32845
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8647
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.83771
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46726
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	3.26445
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867684
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.6794
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3564
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38262
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04458
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.76859
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1807
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892905
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1221
Acute Myeloid Leukemia_LAML_TCGA-AB-2915-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90654
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61004
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44361
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	2.60069
cebpa_22442349_pbmc_lof_human_gpl570_gds4407	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.858269
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43972
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10194
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8217
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839725
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.913964
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02715
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
ZR-75-30	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7565
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2333
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.920485
KU812	DepMap CRISPR Gene Dependency	1.0	2.16205
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3305
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1475
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51886
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.16534
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68677
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2593
YUHOIN0650	DepMap CRISPR Gene Dependency	1.0	3.15021
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46414
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947522
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.874982
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11968
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07716
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5274
CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89566
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0228
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4047
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.04473
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4001
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.999599
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01267
Lung squamous cell carcinoma_LUSC_TCGA-66-2763-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32589
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8326
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38258
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81637
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.4905
CAL29	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45341
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4866
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850933
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5371
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03271
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92686
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5449
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.41454
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5641
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39605
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.734161
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71734
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29646
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8289
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4642
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.32542
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64284
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20159
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09298
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986921
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.17743
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36186
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09946
WM1799	DepMap CRISPR Gene Dependency	1.0	2.49035
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.1939
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27764
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901012
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963202
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54075
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-2.88365
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28461
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2292
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1155
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934178
ELP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69778
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.17459
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3777
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03953
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07063
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.09105
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06921
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
SIMA	DepMap CRISPR Gene Dependency	1.0	3.46632
SIMA	CCLE Cell Line Gene CNV Profiles	1.0	1.39412
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.98929
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07063
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2484
RCC-ER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36528