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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.12152 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.5156 TE-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08037 PRXL2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5807 ENDOU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82452 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 ZNF512B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60523 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23037 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null signaling receptor activity GO Molecular Function Annotations 2015 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34167 SMYD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32446 SKMEL2 DepMap CRISPR Gene Dependency 1.0 3.1249 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.7729 detection of chemical stimulus GO Biological Process Annotations 2015 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35942 HCC1319 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830455 RB1_KD_GSE50532_641_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SREBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15328 TRPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51952 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null ASPC1 DepMap CRISPR Gene Dependency 1.0 2.16526 TMEM229A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75062 Olfactory receptor InterPro Predicted Protein Domain Annotations 1.0 null BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MC1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19267 GSE119978,GSE180930_0_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE135350_3_v_7_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null ACY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54119 NUCB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37619 CCIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85855 ZNF646 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78416 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null ZNF501 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56112 ANHX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25832 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82794 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2559 SPRED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90627 PRR14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67217 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66784 HKA1 DepMap CRISPR Gene Dependency 1.0 2.05994 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.14893 CDX2-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZZEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0377 CHEK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18123 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles 1.0 1.47237 RNF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9765 PMS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9132 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.41027 SFRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60063 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE217132_0_v_1_pfkfb4_human RummaGEO Gene Perturbation Signatures -1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.947781 SW 620 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4375 OKAJIMA Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984614 NOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9819 TMEM185A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60615 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66866 SFMBT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15126 DNAJC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51474 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null UACC893 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.676968 ABCA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95994 DLD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63467 ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6362 PITX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4526 NOP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01264 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874351 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8684 TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30212 Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STXBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78572 KIRREL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95846 RERF-GC-1B COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.866586 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0949 MPST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16066 ADAM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80357 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51856 EKVX Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22692 olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0392 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.928738 EIF1AY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31995 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.44658 RFX7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4693 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49677 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.960385 ventral posterior medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.836227 EMC-BAC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8544 MDA-MB-134-VI Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928634 Brain Lower Grade Glioma_LGG_TCGA-DU-6542-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A496-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23412 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13968 RAD18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99636 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.73207 GPR153 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82721 CORL105 CCLE Cell Line Gene CNV Profiles -1.0 -1.58451 YIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98854 HECTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94301 biological regulation GO Biological Process Annotations 2015 1.0 null NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.51489 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.0016 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28914 Saphenous vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.75 RPL22L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77984 inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.950243 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35833 ZNF219 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22365 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE140997_4_v_7_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null IQCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87015 LTC4S CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11108 TM31 CCLE Cell Line Gene CNV Profiles 1.0 1.45787 B4GALT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12086 FOXR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82707 GGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13893 PLS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35146 TACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29384 SDR39U1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52272 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28523 NR4A1_02_84 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 5.80735 SLC27A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83132 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SP-01A-31R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4863 CSRNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99177 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859237 TRMT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93588 AR ChEA Transcription Factor Targets 1.0 null SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0818 TMEM74B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7395 TM7SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76846 MED13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83956 CNTRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85191 SLITRK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9333 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6726 SGSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88706 RBPMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8037 Olfactory transduction KEGG Pathways 2026 1.0 null BEND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4728 GSE143406_1_v_0_carfilzomib_human RummaGEO Drug Perturbation Signatures 1.0 null POLR2AphosphoS2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16014 ZNF443 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67201 ADAM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24819 PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PRMT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01492 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.87407 DLX1_02_55 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.89885 DACH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25179 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.98786 ACBD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71977 NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3125 GBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22331 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles 1.0 0.828962 Perturb_625_KD_IGF2BP3_SRP068523 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.96078 C1orf115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76829 neuro2a BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.0595 TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H727 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DAB2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52695 ZNF705B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89438 SKGII DepMap CRISPR Gene Dependency 1.0 2.01273 primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05405 GSE171180,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null membrane GO Cellular Component Annotations 2015 1.0 null ZFP36L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.28271 WM-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01188 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.65298 GPATCH11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86556 BACH1_02_17 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.0 SHMAC5 DepMap CRISPR Gene Dependency 1.0 2.13023 MDA-MB-157 COSMIC Cell Line Gene Mutation Profiles 1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06899 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58004 ventral posterior inferior nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00754 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.07132 Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0905 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5193 Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DHX58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5791 DUXB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93697 SKMEL28 CCLE Cell Line Gene CNV Profiles -1.0 -1.63906 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874351 Pineal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.236 FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2927 MEG-01 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87154 detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null TMEM138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18894 NCIH716 CCLE Cell Line Gene CNV Profiles -1.0 -2.2959 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2174 RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23693 mainolfactoryepithelium.MOE. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66784 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MSH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25366 anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927503 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30834 NPIPB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60409 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15366 ZNF316 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23651 WM983B CCLE Cell Line Gene CNV Profiles -1.0 -2.31387 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0905 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25301 B3GALT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87603 EMSY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53081 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Chediak-Higashi syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.257 NFE2L1_02_32 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 5.45396 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4828 PRDX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4375 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.01 CREBZF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65516 HMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57361 HCC1187 COSMIC Cell Line Gene Mutation Profiles 1.0 null JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9314 KLF5-20875108-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55867 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.824385 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8914 FLVCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8669 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18287 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41691 ARL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33912 ADPRS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20588 TP53_01_68 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.68404 ZNF280D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13373 SET CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8673 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.79569 ZNF333 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19761 A253 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 104.597 ZNF730 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0564 SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null CAMSAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07204 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 130.592 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0273 olfactory receptor activity GO Molecular Function Annotations 2015 1.0 null SMAD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28488 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65059 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.978799 NFYB_02_24 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.32193 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.923416 Lung adenocarcinoma_LUAD_TCGA-49-4505-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EEF1AKMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30515 Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08557 receptor activity GO Molecular Function Annotations 2015 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61495 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.43136 ABHD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17397 EZH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82215 RVH421 DepMap CRISPR Gene Dependency 1.0 2.47863 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28914 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.964965 TMEM126B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67292 DB DepMap CRISPR Gene Dependency 1.0 2.53234 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.5763 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5617 regulation of biological process GO Biological Process Annotations 2015 1.0 null ZNF217-24962896-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78903 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.79688 LLPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64776 TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.37467 RND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02787 LYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29617 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874351 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01884 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78645 hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.94058 XYLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84754 DOK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54633 Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null B4GAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67524 ACOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06413 OE21 CCLE Cell Line Gene CNV Profiles -1.0 -1.33705 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22597 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL285 DepMap CRISPR Gene Dependency 1.0 2.39763 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.06477 PCTP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42512 EP300 ENCODE Transcription Factor Targets 1.0 null SEL1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11768 detection of stimulus GO Biological Process Annotations 2015 1.0 null TPRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8272 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4629 GSE140997_4_v_8_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null ALDH18A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70625 TNRC6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42013 HEC265 DepMap CRISPR Gene Dependency 1.0 2.20402 ZGRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70889 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.0878 SAFB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86909 FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18287 HOXD11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9651 PHF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82433 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GP-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14469 JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27775 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70774 FOXM1_02_37 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.45943 E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KCTD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47706 KU812 CCLE Cell Line Gene CNV Profiles 1.0 1.34832 HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.69942 H2AC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00805 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDGFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30705 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58141 Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04163 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.969564 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0377 ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8248 DUSP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48641 GSE135350_3_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5198 NOCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07674 Brain Lower Grade Glioma_LGG_TCGA-P5-A781-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34475 inner CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.891961 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22213 mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05221 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28914 LPS27 DepMap CRISPR Gene Dependency 1.0 2.96848 SMPD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93305 ERCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44698 GATA3-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OTX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1563 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.82856 TCF4-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73A-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null QSOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34031 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5441-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYA_02_76 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 6.65583 DDX19A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81524 ARL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05259 KLHDC7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63323 UNCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03863 SHROOM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86217 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.61287 ISOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62987 NIPA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68454 PRKACB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76862 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8128 496100426_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.08533 ICC10 DepMap CRISPR Gene Dependency 1.0 3.5472 FOXH1-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TE10 CCLE Cell Line Gene CNV Profiles 1.0 1.44029 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.976058 SLR24 DepMap CRISPR Gene Dependency 1.0 2.30263 ZNF728 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44209 KP3 DepMap CRISPR Gene Dependency 1.0 2.58613 SMIM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61262 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2015 1.0 null MYF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94761 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12787 MKN1 COSMIC Cell Line Gene Mutation Profiles 1.0 null mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.897555 H2AFZ ENCODE Transcription Factor Targets 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.22225 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31127 RUNX2 ChEA Transcription Factor Targets 1.0 null NUTM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9786 RNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68672 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28523 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A762-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZR751 CCLE Cell Line Gene CNV Profiles -1.0 -1.52374 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05424 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.49379 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 86.9576 SCN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1155 SCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.44358 ERI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15483 GLUD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10469 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.245 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.208 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.5878 SPAG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38639 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9203 GSTCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97284 amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.964965 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29164 IGR39 CCLE Cell Line Gene CNV Profiles 1.0 1.83417 ZNF347 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93872 Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871776 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT5A_02_72 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.70966 PMC4051124-1471-2164-15-256-S11.XLSX-WES_MSMD-STAT1-Target_STAT1 Rummagene Transcription Factor Associations 2026 1.0 null FEM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62015 BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.6737 plasma membrane GO Cellular Component Annotations 2015 1.0 null ZNF614 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 TRUB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.44171 TRIM56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86008 orbital frontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27031 EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.12099 layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35774 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28914 JHH5 CCLE Cell Line Gene CNV Profiles 1.0 2.29376 ELF5 ChEA Transcription Factor Targets 1.0 null SP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.866789 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10811 ZNF414 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12029 kidney GTEx Tissue Gene Expression Profiles -1.0 -0.98892 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.8134 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A2780 COSMIC Cell Line Gene Mutation Profiles 1.0 null TSN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96735 GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1647 NEMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9128 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02961 496100667_TCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 13.9473 DIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96377 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.846371 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24941 PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null LDB1_02_35 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.66297 PURG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96995 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10194 POM121C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48315 NANOG ChEA Transcription Factor Targets 1.0 null ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.2321 substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.53755 NDUFAF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63265 Expression and translocation of olfactory receptors Reactome Pathways 2024 1.0 null KPL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.47619 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EVX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16297 MCCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72661 Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04244 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.51263 TMEM258 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29118 WIPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23241 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10588 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null MOLT-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null INSR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39571 LRRFIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61744 USF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80094 UBN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66564 NCOA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46834 FIS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22744 DUSP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57228 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.19606 TRAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49006 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PRDM14-20953172-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ETFBKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87905 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3653 hippocampus (hippocampal formation)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29547 CIDEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46264 NKX2-5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.43 CYP26A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09472 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29087 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0072 TXNDC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56768 CHD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37094 PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.827667 ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.39463 RBM48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34538 BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0197 ventrolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13341 NEU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5921 basolateral nucleus (basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12733 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.1684 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5293 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3117 AGPAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.371 lung GTEx Tissue Gene Expression Profiles -1.0 -0.98892 rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916621 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05473 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MATK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77796 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962901 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF217-24962896-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null F12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67726 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0853 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3069 CHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4215 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66784 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49341 PMC12882460-12943_2025_2548_MOESM1_ESM.xlsx-Table_S3-T1_RGS1_CREM_CREM Rummagene Transcription Factor Associations 2026 1.0 null PCYOX1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83569 transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null TBCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2548 SAP18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6787 CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TDG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61602 ZNF462 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65597 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0265 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KIAA0753 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38255 ERGIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75805 inner CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.982339 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.925731 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.969564 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.43894 Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF816 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22715 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4718 PRKCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52157 NCIH2073 CCLE Cell Line Gene CNV Profiles -1.0 -2.04412 C15orf39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00018 H3-5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89653 WHSC1_02_66 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.22239 TRIP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06019 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47942 OCIMY5 DepMap CRISPR Gene Dependency 1.0 2.83538 ZNF23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96848 GSE182680,GSE182683_7_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null ITLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.363 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3587 AR-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE140997_4_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null NCIH2052 CCLE Cell Line Gene CNV Profiles 1.0 1.47 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1428 DepMap CRISPR Gene Dependency 1.0 2.13666 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.7151 CXCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44312 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0219 PSIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90579 USP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62768 ELF5-23300383-T47D-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HMX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16468 BFTC-905 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZEB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4742 TWSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53597 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7795 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15298 PCDHB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17975 MOSPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.55949 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15074 GTF2I CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04458 HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83864 NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.784 TBPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98994 H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STARD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63437 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70717 membrane LOCATE Predicted Protein Localization Annotations 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16066 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984614 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.8309 C1QTNF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76628 BT474 CCLE Cell Line Gene CNV Profiles 1.0 1.7992 FOXA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05467 dorsolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.901041 SEMA3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90969 vomeralnasalorgan.VMO. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.915006 LEMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5146 GSE182680,GSE182683_5_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null NFYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1069 MYOCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3963 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXD3_02_83 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.70044 ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15539 PTPN14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36695 Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13877 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2342 CASTOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01382 ENTPD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85437 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202744_1_v_3_toyocamycin_human RummaGEO Drug Perturbation Signatures 1.0 null FOXA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15006 BLOC1S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68749 PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1 Rummagene Transcription Factor Associations 2026 1.0 null NELFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52347 NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null TRIM27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6881 MALME3M CCLE Cell Line Gene CNV Profiles -1.0 -1.57717 DMS114 CCLE Cell Line Gene CNV Profiles -1.0 -1.36322 ATOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48649 SUM102PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.03802 ZFPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51232 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9802 SNU182 CCLE Cell Line Gene CNV Profiles 1.0 2.66634 integral component of membrane GO Cellular Component Annotations 2015 1.0 null SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7279 signal transduction GO Biological Process Annotations 2015 1.0 null KP4 DepMap CRISPR Gene Dependency 1.0 2.47016 CALU-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null ST14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6085 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7052 MBOAT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72352 NMRAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7098 CAL-29 COSMIC Cell Line Gene Mutation Profiles 1.0 null Obstructive hydrocephalus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.338 THEM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88385 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87294 TLE2_02_53 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 5.77259 A498 CCLE Cell Line Gene CNV Profiles -1.0 -1.44275 KRT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99671 CORL311 DepMap CRISPR Gene Dependency 1.0 2.02307 H3K27me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARRDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7842 DNASE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93324 PTPRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45267 SLVL DepMap CRISPR Gene Dependency 1.0 2.10165 NRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86407 TASOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37885 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COL9A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57669 PRKAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18095 HAL-01 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26316 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERLIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42523 G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null E2F4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11386 GSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0296 EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10893 PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null MRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47498 496100466_PCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1047 rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46496 SUP-HD1 COSMIC Cell Line Gene Mutation Profiles 1.0 null A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962901 ADGRL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69737 membrane part GO Cellular Component Annotations 2015 1.0 null medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23898 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SNU478 DepMap CRISPR Gene Dependency 1.0 2.26798 dorsolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.964965 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30466 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF Rummagene Transcription Factor Associations 2026 1.0 null DCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65705 CDK11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72158 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30624 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.71361 PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null MCTS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80843 KLF5-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null IRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88158 GTF3C5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36185 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.04447 FNDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88077 SLVL COSMIC Cell Line Gene Mutation Profiles 1.0 null CSTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15832 LC-1-SQ COSMIC Cell Line Gene Mutation Profiles 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874351 SNU738 DepMap CRISPR Gene Dependency 1.0 2.32588 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20183 Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DPH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44535 PLEKHG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35389 GSE139455_7_v_3_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE135350_2_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.74922 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 97.3924 regulation of cellular process GO Biological Process Annotations 2015 1.0 null PRNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37635 UBXN2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54147 STEEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31272 MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.706962 FHIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29821 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20C-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.972264 MORF4L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82037 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.840627 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59736 bladder GTEx Tissue Gene Expression Profiles 1.0 1.64442 RAB11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40808 TNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48036 ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3311 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.06477 MYC ChEA Transcription Factor Targets 1.0 null striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58207 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46767 NEIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06388 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.16954 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.92952 HOXB4_02_64 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.11548 G130 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874351 embryoday10.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.98067 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14038 ADSS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78001 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.0285 PLEKHA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4233 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18553 USO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13832 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8801 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87294 USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3704 FLI1 ChEA Transcription Factor Targets 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.45 TE11 CCLE Cell Line Gene CNV Profiles 1.0 1.89392 anteroventral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910806 PRCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08832 outer SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11463 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null PANC0504 DepMap CRISPR Gene Dependency 1.0 3.01181 DDX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30875 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06952 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26787 SEC24A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87207 ZNF217 ChEA Transcription Factor Targets 1.0 null COLO678 CCLE Cell Line Gene CNV Profiles -1.0 -1.92656 Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20453 PACSIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15032 SIGIRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71598 ETV3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90449 59M DepMap CRISPR Gene Dependency 1.0 3.03234 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28523 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.6725 PANC0813 CCLE Cell Line Gene CNV Profiles 1.0 1.56465 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null KU1919 CCLE Cell Line Gene CNV Profiles -1.0 -1.42318 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.6686 GSE135350_2_v_7_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null USP31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33971 GSE150895,GSE150896_0_v_1_kif15_human RummaGEO Gene Perturbation Signatures -1.0 null DIABLO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2478 EZH2 ENCODE Transcription Factor Targets 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ADPRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63399 SLC48A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21165 ZNF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7203 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927503 Prostate adenocarcinoma_PRAD_TCGA-EJ-7788-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54457 KLF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27464 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57491 SN12C COSMIC Cell Line Gene Mutation Profiles 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null NCIH1693 DepMap CRISPR Gene Dependency 1.0 3.30599 PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null RAB1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61611 VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.838943 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate-t cell Tabula Sapiens Gene-Cell Associations 1.0 0.541607 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null ARHGEF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19592 RASSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02015 mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.87483 GSE150895,GSE150896_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null PNMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95078 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.92952 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.827392 KCTD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57171 BOLA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48403 SNX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56141 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30325 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.509 C1RL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5375 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.52004 NCIH322 CCLE Cell Line Gene CNV Profiles -1.0 -2.04518 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0476 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.922244 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1843 INTS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25995 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.30993 Pinealocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.822 NUDT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79688 SOX12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9587 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27536 ZBED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40533 Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.31447 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 RTL8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40874 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6232 TBL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43888 ZNF284 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96833 GSE134986_2_v_8_oma1_human RummaGEO Gene Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22714 SF295 CCLE Cell Line Gene CNV Profiles -1.0 -1.55117 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0034 RDES CCLE Cell Line Gene CNV Profiles 1.0 1.49407 RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GCHFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35845 NCIH520 DepMap CRISPR Gene Dependency 1.0 3.18423 GARIN5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33132 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40096 signal transducer activity GO Molecular Function Annotations 2015 1.0 null Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875015 ZNF121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55748 anterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08074 MYB-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H1648 COSMIC Cell Line Gene Mutation Profiles 1.0 null TMEM17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882 Olfactory Signaling Pathway Reactome Pathways 2014 1.0 null H3K27me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5938 DOCK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41912 TBC1D2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50245 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.856364 GSC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2033 AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null BCL6-25482012-CML-JURL-MK1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF283 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91539 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.76562 ACCMESO1 DepMap CRISPR Gene Dependency 1.0 2.71882 HSC3 CCLE Cell Line Gene CNV Profiles -1.0 -2.42752 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 CTRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56373 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.948682 TAL1-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null DNTTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16287 H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37482 RNF2_02_68 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 6.06967 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84542 MICAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76119 TEX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18246 MYC-18940864-HL60-human ChEA Transcription Factor Binding Site Profiles 1.0 null MEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54711 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.82734 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.771096 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2992 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20789 DNAJC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55534 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45977 Epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.17 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DRAXIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67487 SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962901 PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.42085 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null olfactory receptor activity GO Molecular Function Annotations 2025 1.0 null ILVBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04153 DHRS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60279 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51811 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.09477 Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAPKAPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61766 KMT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96041 PHF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56336 UQCR11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6181 MED15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7141 ERG ChEA Transcription Factor Targets 1.0 null DYNLT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45842 IL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21692 G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996959 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24776 PDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00675 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0265 EEF1AKMT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73797 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.932039 GSE182680,GSE182683_7_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null VPS33A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31214 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0576 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -0.98892 GSE189336_1_v_0_nitric oxide_human RummaGEO Drug Perturbation Signatures -1.0 null SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.595307 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.900362 SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.5755 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0715 STRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03989 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13968 Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69344 YMB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.54455 GLYR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46262 SPSB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07183 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17853 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Signal Transduction Reactome Pathways 2014 1.0 null FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9958 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51811 KDM3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19628 primary motor-sensory cortex (samples)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.899805 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.47502 TRRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24293 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67887 TRIM28 ChEA Transcription Factor Targets 1.0 null RNF19B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5644 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40096 PIP4K2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35204 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6417 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66852 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.0843 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1503 SH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.858082 NGLY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69444 GSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38134 HSFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88967 CRMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61004 TE5 CCLE Cell Line Gene CNV Profiles 1.0 2.8676 SF539 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24013 PCNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74889 ANO8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7162 GLRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24258 MOSPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08974 Signaling by GPCR Reactome Pathways 2014 1.0 null CTSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52113 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.98787 VCPKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84921 FIBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36174 USP9X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50642 P3H3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40424 IL17RE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69124 CMTM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75634 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1881 HNF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92223 NDUFS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37688 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.989601 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15539 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SFR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78699 HOXC10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2864 TCEA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28581 HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.604091 C6orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84766 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.60982 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0529 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.9427 NKX6-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76716 Silicosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 ZNF180 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87332 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35096 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1935 LMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65476 UNC5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83447 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRPF38A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90368 SMC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61191 KCTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69071 POLH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22551 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.832773 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18449