association	dataset	threshold value	standardized value
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.59189
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1189
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16322
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.6124
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.14851
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
ER membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948753
MAF_01_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60065
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895848
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EW8	DepMap CRISPR Gene Dependency	1.0	3.01496
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5903
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.873638
PA1	DepMap CRISPR Gene Dependency	1.0	5.38472
Childhood disintegrative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3417
A673	DepMap CRISPR Gene Dependency	1.0	2.65693
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0882
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931237
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2971
MORCPR	CCLE Cell Line Gene CNV Profiles	1.0	1.76903
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3336
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948753
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6396
WM1799	CCLE Cell Line Gene CNV Profiles	1.0	1.76519
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7585-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834414
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00471
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.969744
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27485
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	1.33822
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999069
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2854-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62352
MKN45	DepMap CRISPR Gene Dependency	1.0	2.15313
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.2318
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9977
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47585
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BEN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	1.40366
PADI4	ChEA Transcription Factor Targets	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37574
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77959
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27575
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.0789
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7905
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8165
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7552
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46449
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.731752
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61674
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99074
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4815
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0981
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07771
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.963649
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.941
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-1.17303
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19877
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08879
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU449	DepMap CRISPR Gene Dependency	1.0	2.04596
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
697	DepMap CRISPR Gene Dependency	1.0	5.95203
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1161
Olfactory transduction	KEGG Pathways 2026	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0332
JUND	ENCODE Transcription Factor Targets	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07841
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7859
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06772
EFE184	DepMap CRISPR Gene Dependency	1.0	3.05124
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9968
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2653
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1769
cellular_component	GO Cellular Component Annotations 2015	1.0	null
PMC3919509-NIHMS471461-supplement-3.xls-Table_S1-ZNF33A_ZNF33A	Rummagene Transcription Factor Associations 2026	1.0	null
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
JHH1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41332
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0032
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.54147
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3885
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1645
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05427
D-263MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0621
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82155
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.0471
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3478
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0578
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6711
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931808
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94422
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.275
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4219
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86188
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46001
EFE184	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36828
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24205
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NL-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.653
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.40762
RHJT	DepMap CRISPR Gene Dependency	1.0	2.04594
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COLO679	DepMap CRISPR Gene Dependency	1.0	2.49491
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7883
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7108
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18927
OE21	DepMap CRISPR Gene Dependency	1.0	3.58233
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1806
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.53281
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
HS936T	DepMap CRISPR Gene Dependency	1.0	2.24665
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.1174
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9458
FADU	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18486
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2543
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.484
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89367
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.993188
CTCF	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837032
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76339
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1501
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.461
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80082
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.66286
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0332
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29615
ELF5	ChEA Transcription Factor Targets	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1855
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F6-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0161
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Lung squamous cell carcinoma_LUSC_TCGA-46-3767-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL120	DepMap CRISPR Gene Dependency	1.0	2.70681
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.22213
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.02548
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.870148
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.43125
SAOS-2	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02989
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895848
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5476
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896877
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9358
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SF126	DepMap CRISPR Gene Dependency	1.0	4.21106
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19351
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCFSTTG1	DepMap CRISPR Gene Dependency	1.0	4.62126
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0332
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980016
Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6822
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875102
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47845
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.817
496100447_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.96925
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.51382
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6396
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29511
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824994
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23047
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.54706
KYSE510	CCLE Cell Line Gene CNV Profiles	1.0	1.42649
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83869
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948303
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0909
BICR16	DepMap CRISPR Gene Dependency	1.0	2.46811
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13269
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8785
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2663
Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19097
SNU601	DepMap CRISPR Gene Dependency	1.0	2.98358
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.11581
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ICC15	DepMap CRISPR Gene Dependency	1.0	2.3841
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.547
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.88033
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6847
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1836
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23101
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHD1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6766
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3449
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67367
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0003
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24718
Sarcoma_SARC_TCGA-PC-A5DL-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43865
BXPC3	DepMap CRISPR Gene Dependency	1.0	3.68077
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36811
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5607
GI1	DepMap CRISPR Gene Dependency	1.0	2.93355
DEL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51916
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0003
IALM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07192
LNZ308	DepMap CRISPR Gene Dependency	1.0	2.29149
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18991
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1959
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61297
KG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89501
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17652
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10135
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896877
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0226
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.98293
U2904	DepMap CRISPR Gene Dependency	1.0	4.86641
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4013
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72247
PK1	CCLE Cell Line Gene CNV Profiles	1.0	2.01451
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6127
Signal Transduction	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5035
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02928
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78127
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37926
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27613
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.144
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	2.35138
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.88189
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.451
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1286
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26483
NCIN87	DepMap CRISPR Gene Dependency	1.0	3.29188
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6863
membrane part	GO Cellular Component Annotations 2015	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1159
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0311
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58785
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4668
Acute Myeloid Leukemia_LAML_TCGA-AB-3001-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.66686
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73972
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27575
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75885
NCIH1436	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13217
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13634
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897414
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7614
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.853541
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03903
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81289
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00471
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97081
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22821
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962792
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.13531
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6678
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5055
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44108
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9777
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8403
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89501
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5616
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7106
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.37175
MDA-MB-175-VII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962792
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.872477
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9237
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GP5D	DepMap CRISPR Gene Dependency	1.0	3.41191
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3799
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03663
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.947953
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4417
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.275
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0224
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.4932
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9969
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK20ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3626
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15748
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.997383
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8396
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5174
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
253J	DepMap CRISPR Gene Dependency	1.0	4.03209
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27698
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889297
SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.50462
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0332
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	90.45
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862137
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1395
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3366
HS729	DepMap CRISPR Gene Dependency	1.0	2.1847
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4428
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5148
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4997
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.058
Acute Myeloid Leukemia_LAML_TCGA-AB-2844-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44108
Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8178
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7187
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC7	DepMap CRISPR Gene Dependency	1.0	2.29505
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875102
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-2.33227
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15441
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889297
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976995
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21992
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999069
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24944
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.9998
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC205	DepMap CRISPR Gene Dependency	1.0	2.80846
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0215
biological_process	GO Biological Process Annotations 2015	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44031
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3322-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.976
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08879
UMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40277
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20888
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07428
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5589
U-CH2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9448
Lung squamous cell carcinoma_LUSC_TCGA-60-2704-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4758
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.17303
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9963
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23047
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62315
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3727
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4103
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0078
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9749
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1836
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58034
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0598
PSN1	DepMap CRISPR Gene Dependency	1.0	3.96716
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76269
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27024
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36394
SKNFI	DepMap CRISPR Gene Dependency	1.0	2.60409
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43865
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.906732
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72289
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962792
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.85112
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100306_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15082
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46744
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68031
ECC4	DepMap CRISPR Gene Dependency	1.0	2.66839
ST486	CCLE Cell Line Gene CNV Profiles	1.0	2.12969
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	5.22955
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2416
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86265
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862137
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04387
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.414
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9045
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0737
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6463
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2402
H3K9me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.39474
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11611
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37906
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.01784
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903998
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.87
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.849
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05473
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.89307
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61492
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.58799
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01067
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39103
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.970036
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2658
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947575
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44411
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0062
KIJK	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50036
U937	CCLE Cell Line Gene CNV Profiles	1.0	2.59981
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09253
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.813184
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4326
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.036
PAX6	ChEA Transcription Factor Targets	1.0	null
JUND_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	3.34865
SCC4	DepMap CRISPR Gene Dependency	1.0	3.54336
RD	DepMap CRISPR Gene Dependency	1.0	3.19297
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2199
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BEN	CCLE Cell Line Gene CNV Profiles	1.0	2.01562
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861189
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.438
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIAML3	DepMap CRISPR Gene Dependency	1.0	7.19095
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19033
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.97
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8537
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0853
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46449
JHH2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20028
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35535
EZH2	ENCODE Transcription Factor Targets	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01657
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876526
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4521
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16413
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8287
CAL62	CCLE Cell Line Gene CNV Profiles	1.0	1.4285
SAP30	ENCODE Transcription Factor Targets	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.962344
CORL105	CCLE Cell Line Gene CNV Profiles	1.0	2.05074
GCIY	DepMap CRISPR Gene Dependency	1.0	2.84743
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48944
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01782
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29979
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.166
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6145-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6446
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6922
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2521
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895848
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961669
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5477
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922922
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3902
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.08
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1574
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
RUNX3	ENCODE Transcription Factor Targets	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7285
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16256
Acute Myeloid Leukemia_LAML_TCGA-AB-2949-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2074
Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1105	DepMap CRISPR Gene Dependency	1.0	6.97776
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	2.8227
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4425
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10666
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.068
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35479
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3843
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4207
496100606_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.83722
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843055
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2952
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.858434
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2906
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895848
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.16055
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4805
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4687
NMC-G1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.99074
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V6-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837032
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0443
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1836
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8062
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14228
H2369	COSMIC Cell Line Gene Mutation Profiles	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.17303
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A2C7-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48944
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843226
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.63183
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7595
KYSE450	CCLE Cell Line Gene CNV Profiles	1.0	1.53308
LS	DepMap CRISPR Gene Dependency	1.0	2.61389
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.889
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3561
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.952154
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9752
H3K36me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87522
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5097
COLO320	DepMap CRISPR Gene Dependency	1.0	3.45886
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74413
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902963
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962792
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9594
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37021
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990497
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889297
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.656
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7457
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.292
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0738
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.42754
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04012
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.94241
EVSA-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5931
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.4319
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8561
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2879
SPI1	ENCODE Transcription Factor Targets	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964409
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.494
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8109
KYSE510	DepMap CRISPR Gene Dependency	1.0	2.24979
VMRCRCW	DepMap CRISPR Gene Dependency	1.0	2.47736
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1241
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962792
TUR	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
SIRT1_KO_GDS3666_295_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862137
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4021
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977159
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0879
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08879
cyclophosphamide_homo sapiens_gpl5104_gse27930	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21992
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	ChEA Transcription Factor Targets	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.51086
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3668
GB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Oxoglutarate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1233
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73972
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.264
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0312
Signaling by GPCR	Reactome Pathways 2014	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01152
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63663
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4909
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.75314
SUM185PE	DepMap CRISPR Gene Dependency	1.0	3.59798
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864877
NCIH661	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3932
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06215
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70849
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5305
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYO1	DepMap CRISPR Gene Dependency	1.0	2.78478
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11008
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0709
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1ED-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30679
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2457
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.46841
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9964
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896877
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39726
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64052
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02989
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5198
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8266
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3248
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42979
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902963
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8478
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926716
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YH13	DepMap CRISPR Gene Dependency	1.0	3.40599
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.305
Acute Myeloid Leukemia_LAML_TCGA-AB-2805-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4187
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.296
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872308
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2015
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3326-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4595
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0535
RMUGS	CCLE Cell Line Gene CNV Profiles	1.0	1.49512
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.3857
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15039
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6273