association	dataset	threshold value	standardized value
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.317
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4091
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3607
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.36419
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.92052
SNU449	DepMap CRISPR Gene Dependency	1.0	2.20791
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37494
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.434
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00227
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU46	DepMap CRISPR Gene Dependency	1.0	4.1436
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4352
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27895
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.884
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1444
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0025
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8267
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.13811
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2958
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853289
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08702
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-AS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7690-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.38661
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1114
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1539
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885771
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942816
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8856
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1633
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3394
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4828
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2587
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16319
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1669
CTCF	ENCODE Transcription Factor Targets	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46191
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4367
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3929
membrane	GO Cellular Component Annotations 2015	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6929
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.173
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4869
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4788
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906094
MM1S	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50477
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6253
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931364
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14525
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983954
Signaling by GPCR	Reactome Pathways 2014	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A54R-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0856
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.38613
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8598
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0073
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79451
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00562
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.717
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4879
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05037
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8726
EP300_01_297	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.65984
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8221
HUCCT1	DepMap CRISPR Gene Dependency	1.0	2.2992
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0381
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.222
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827145
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	2.06905
MEL-HO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8456
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.195
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8505
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1486
SNU5	DepMap CRISPR Gene Dependency	1.0	2.22748
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850307
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5368
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EV-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02414
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3148
GATA3_01_163	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63248
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18256
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4152
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39929
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2775
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13715
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.934
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3069
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2099
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.02209
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913079
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6981
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.726
OE33	DepMap CRISPR Gene Dependency	1.0	2.66695
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5006
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41279
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83548
MDAMB415	DepMap CRISPR Gene Dependency	1.0	3.53674
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.4186
MPNST724	DepMap CRISPR Gene Dependency	1.0	3.29492
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16319
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48551
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE319	DepMap CRISPR Gene Dependency	1.0	2.72164
PSN1	DepMap CRISPR Gene Dependency	1.0	3.41329
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SKMM2	DepMap CRISPR Gene Dependency	1.0	2.73842
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8705
membrane part	GO Cellular Component Annotations 2015	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.41674
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2597
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17378
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8807
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56709
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.933
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.05
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19223
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19602
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKGII	DepMap CRISPR Gene Dependency	1.0	2.15818
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9253
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3118
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0323
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06241
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6329
MOLM-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67712
HCC1171	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05377
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876824
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7927
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45406
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1504
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05037
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989337
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95034
Olfactory transduction	KEGG Pathways 2026	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85592
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16595
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909822
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TD-01A-51R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39929
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05109
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.022
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2324
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1849
RCM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45643
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	263.414
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2007
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23363
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1037
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2445
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.724
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.4365
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09145
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35942
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7162
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32639
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8199
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45197
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63244
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6069
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3438
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909822
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2861
HCC-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLE	DepMap CRISPR Gene Dependency	1.0	2.00125
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88589
H3K9me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NG-01A-31R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00562
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2832
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7078
L1236	DepMap CRISPR Gene Dependency	1.0	2.85376
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2119
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.52059
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4556
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.41818
RBBP5	ENCODE Transcription Factor Targets	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.50232
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00343
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
D283MED	DepMap CRISPR Gene Dependency	1.0	2.40196
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48829
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3107
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40264
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.1726
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1595
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.24741
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3842
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.79703
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10516
Primary open angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.843313
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34636
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3073
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3370-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8877
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9296
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6867
769P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55195
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05037
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.70431
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.712702
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV644	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10203
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7254
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8637
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6641
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57002
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6158
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3678
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7109
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09792
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60508
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.53931
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32639
H3K9me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9023
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52686
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.35005
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847166
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64806
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4206
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6669
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.32058
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914831
HT1197	DepMap CRISPR Gene Dependency	1.0	13.0313
ML1	CCLE Cell Line Gene CNV Profiles	1.0	1.64047
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3302
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2071
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947677
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.876812
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8113
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.082
SC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980733
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4874
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3149
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64323
127399	DepMap CRISPR Gene Dependency	1.0	7.61941
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6926
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU3F2	ChEA Transcription Factor Targets	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	1.34662
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1948
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7633
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7919
NCI-H2171	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
response to stimulus	GO Biological Process Annotations 2015	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866996
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.042
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH5	DepMap CRISPR Gene Dependency	1.0	2.9234
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7765
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90914
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8157
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56709
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.00859
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9444
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10804
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00562
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00562
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1707
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4862
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.827982
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0011
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.872371
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859631
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2915
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866996
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KNS60	DepMap CRISPR Gene Dependency	1.0	2.09969
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3789
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9735
SUM149PT	DepMap CRISPR Gene Dependency	1.0	5.32261
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51178
H3K9me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3803
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.17235
EFM-192A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00562
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1851
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9624
Signal Transduction	Reactome Pathways 2014	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55334
Prostate adenocarcinoma_PRAD_TCGA-EJ-5526-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.726
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.903778
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1689
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31669
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
RUNX1-22343733-KASUMI1-HUMAN-PERIPHBLOOD-AML	ChEA Transcription Factor Targets 2022	1.0	null
SF172	DepMap CRISPR Gene Dependency	1.0	2.62039
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5647
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08605
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8218
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53934
Pancreatic adenocarcinoma_PAAD_TCGA-RB-A7B8-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4333
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3473
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28287
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.40471
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07159
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4133
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2262
JHOM1	CCLE Cell Line Gene CNV Profiles	1.0	1.59919
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.149
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76837
H3K9me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50066
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04938
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866996
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32569
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.844965
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7201
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34354
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.427
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41913
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08702
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88759
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23237
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941922
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43957
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44463
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03917
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4668
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85452
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4257
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44262
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46191
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3135
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90914
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2713
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84469
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U4-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877661
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933585
TE14	CCLE Cell Line Gene CNV Profiles	1.0	2.152
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09792
Sarcoma_SARC_TCGA-IW-A3M6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7807
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869944
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QI-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6753
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9804
SNU16	CCLE Cell Line Gene CNV Profiles	1.0	1.86632
CHLA57	DepMap CRISPR Gene Dependency	1.0	3.4647
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869944
COLO320	DepMap CRISPR Gene Dependency	1.0	5.03058
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2861
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7962
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854814
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3494
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6334
vagina	GTEx Tissue Gene Expression Profiles	1.0	0.967612
PACADD188	DepMap CRISPR Gene Dependency	1.0	3.68002
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89984
S117	DepMap CRISPR Gene Dependency	1.0	3.13333
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7502
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16207
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5655
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00562
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1344
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15569
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909822
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11373
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31539
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.3253
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0298
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3516
signal transduction	GO Biological Process Annotations 2015	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4538
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.95427
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2696
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14716
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.62192
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866996
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26726
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.826121
SW1710	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46081
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2656
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7837
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23637
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06574
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982216
CHD1	ENCODE Transcription Factor Targets	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.91683
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7285
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A199-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8455
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5492
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05112
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03891
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.185
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.3632
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9802
H3K9me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	1.99093
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60896
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4702
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1321
LN340	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36956
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4563
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05895
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.772806
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	17.1364
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8552
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0567
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7387
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3319
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	2.18218
MM370	DepMap CRISPR Gene Dependency	1.0	2.39151
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68317
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.33284
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06555
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	1.0	1.46555
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11123
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.53977
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90914
CBX3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3117129-mp2010119x5.xls-CRS_Amg-Unnamed_5_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94996
MAC2A	DepMap CRISPR Gene Dependency	1.0	2.31182
NCIH727	DepMap CRISPR Gene Dependency	1.0	2.124
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.62662
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1221
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28099
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16319
HO1U1	DepMap CRISPR Gene Dependency	1.0	2.82275
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09792
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2791
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35871
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0901
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
DNAJC2	ChEA Transcription Factor Targets	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42962
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3706
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40162
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09703
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9586
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14525
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.9684
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.41991
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931364
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96008
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840703
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5529
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53934
CAL27	DepMap CRISPR Gene Dependency	1.0	3.82631
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.022
TRIM28	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34398
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8494
SNU1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48431
cellular_component	GO Cellular Component Annotations 2015	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47855
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.533
KMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3394
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2166
SETDB1	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12381
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9857
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.33525
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06141
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64809
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2658
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43473
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.4376
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30578
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973753
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6495
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2302
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.971
molecular_function	GO Molecular Function Annotations 2015	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5463
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.93429
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23363
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5597
MDAMB157	DepMap CRISPR Gene Dependency	1.0	2.56056
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6761
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3081
CH157MN	DepMap CRISPR Gene Dependency	1.0	2.31836
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0835
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869944
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2337
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9304
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6225
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06241
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00562
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973753
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOP62	DepMap CRISPR Gene Dependency	1.0	2.00693
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	2.60574
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5173-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5399-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8517-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.7811
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5899
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
697	DepMap CRISPR Gene Dependency	1.0	3.00659
SW579	DepMap CRISPR Gene Dependency	1.0	2.01242
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.4737
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0688
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.996
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4793
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6935
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
H3K9me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.794
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.6424
PATU8902	DepMap CRISPR Gene Dependency	1.0	3.77775
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3653
HCA1	DepMap CRISPR Gene Dependency	1.0	3.00609
RB1_KD_GSE50532_654_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
OCIAML3	DepMap CRISPR Gene Dependency	1.0	4.0403
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75357
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4284
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.367
KE37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32448
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93054
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06667
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4511
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4723
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5936
OCIP5X	DepMap CRISPR Gene Dependency	1.0	2.13019
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0886
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3332
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78482
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941922
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4376
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.92088
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887316
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970776
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19387
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JK-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL78	DepMap CRISPR Gene Dependency	1.0	2.20297
CAL-85-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5354
H3K9me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3121
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94252
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.391
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9974
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.915138
3-M syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869944
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6705
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH1	DepMap CRISPR Gene Dependency	1.0	2.78093
SKNFI	DepMap CRISPR Gene Dependency	1.0	4.48868
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAN-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4929
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3861
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.745
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913079
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5369
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2408
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.011
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02535
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HG-A2PA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31669
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1453
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05062
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.52163
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4619
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3958
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7797
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5056
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93602
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73814
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7108
SNU869	CCLE Cell Line Gene CNV Profiles	1.0	1.99409
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.796
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.466
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896755
DOTC24510	DepMap CRISPR Gene Dependency	1.0	2.69326
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.01544
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5759
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8034
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988389
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A824-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866996
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08944
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3606
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18385
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18277
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6038
NCIH2171	CCLE Cell Line Gene CNV Profiles	1.0	3.1659
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.865428
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851879
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4922
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.5768
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0071
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42183
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COGAR359	DepMap CRISPR Gene Dependency	1.0	2.36096
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26671
