association	dataset	threshold value	standardized value
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.57639
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.612
Adipocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8413
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57549
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14425
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5597
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993135
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2511
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01055
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9106
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49194
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4963-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.7819
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88731
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0659
MOLM6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.63595
Sec61 translocon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
biological regulation	GO Biological Process Annotations 2015	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2467
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.656
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.6566
CH157MN	DepMap CRISPR Gene Dependency	1.0	2.92118
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5467
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54443
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6554
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7402
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5097
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8632
WRL-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0799
HMC18	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03576
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4271
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	157.5
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345928
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1875
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856831
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6936
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.81146
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4988
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827221
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0794
LN340	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69821
TE11	CCLE Cell Line Gene CNV Profiles	1.0	1.49837
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Mitochondrial inner membrane assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5449
ML-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8571
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.049831
Hypopharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3731
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5242
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15088
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03377
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2546
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88731
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.6982
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2675
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3237
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957815
Transverse colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3635
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01055
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.988
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7824
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1807
LN18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54922
CORL105	DepMap CRISPR Gene Dependency	1.0	2.55196
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4851
SNU719	DepMap CRISPR Gene Dependency	1.0	2.0534
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4899-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6755
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.343
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0412
SKHEP1	CCLE Cell Line Gene CNV Profiles	1.0	1.57863
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77007
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.69
Reading disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.2059
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	1.35859
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6786
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3875
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60708
cellular_component	GO Cellular Component Annotations 2015	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10282
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881048
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
JHUEM7	DepMap CRISPR Gene Dependency	1.0	2.87459
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934193
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9049
496100667_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	16.191
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4796
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1886
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837198
SNU475	CCLE Cell Line Gene CNV Profiles	1.0	1.91362
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.75
MEC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84649
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7429
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5174
SNU16	DepMap CRISPR Gene Dependency	1.0	2.06332
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0215
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.31485
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-LGG_MYB_L1_deletions-Unnamed_2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17396
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49584
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.05405
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Synovial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12799
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.46505
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIAML3	DepMap CRISPR Gene Dependency	1.0	2.01478
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.632282
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.081
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.86914
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1012
HS729	DepMap CRISPR Gene Dependency	1.0	2.20359
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859899
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11585
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85029
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051184
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
MM386	DepMap CRISPR Gene Dependency	1.0	6.04503
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3808
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26099
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03172
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.515
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.2916
697	DepMap CRISPR Gene Dependency	1.0	3.972
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8738
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5963
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867313
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6242
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28344
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
CAKI2	DepMap CRISPR Gene Dependency	1.0	2.04131
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0339
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.15326
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14516
icSARS CoV_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.561762
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.818
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5967
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902572
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972319
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908767
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Choriodecidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.6681
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.331
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.4275
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3585
KNS81	DepMap CRISPR Gene Dependency	1.0	3.86553
A_CA_04_2009_7dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41279
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.8678
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5472
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2087
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4035
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874178
SKMEL2	DepMap CRISPR Gene Dependency	1.0	2.11785
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6569
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.372
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884672
Koolen de Vries syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8973
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.1549
NP8	DepMap CRISPR Gene Dependency	1.0	3.16245
Olfactory transduction	KEGG Pathways 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53453
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.42048
CAL33	DepMap CRISPR Gene Dependency	1.0	4.77238
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15897
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91876
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944663
Sensory Perception	Reactome Pathways 2024	1.0	null
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Photoreceptor proximal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6751
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
SNU869	CCLE Cell Line Gene CNV Profiles	1.0	1.33451
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2024
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34782
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5082
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993073
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.488
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.785
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900301
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74475
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7856
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5192
membrane part	GO Cellular Component Annotations 2015	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08751
NCIH2172	DepMap CRISPR Gene Dependency	1.0	3.51934
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7318
TC106	DepMap CRISPR Gene Dependency	1.0	2.66225
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.5308
ADAM10	Pathway Commons Protein-Protein Interactions	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9487
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2052
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.35549
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8555
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06907
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8691
Mixed gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872006
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8488
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838908
Intraocular pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972402
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971971
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884672
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970196
496100660_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.58371
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1088
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06854
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4051
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7752
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01373
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20471
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30916
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68642
MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7365
PITX2_01_54	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.78741
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26375
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.429
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08251
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3812
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832651
receptor activity	GO Molecular Function Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20984
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7893
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827221
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69782
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8705
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8354
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08976
EW-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6108
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3108
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2398
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96722
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940512
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837032
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.568
signal transduction	GO Biological Process Annotations 2015	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957815
C80	DepMap CRISPR Gene Dependency	1.0	4.13922
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5056
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.3103
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.122
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19W-06A-41R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.523
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.84961
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.3116
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3579
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31918
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3726
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9978
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.81565
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8982
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80012
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.656
Nucleolar chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7718
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.111
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6427
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6418
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940512
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1284
SW1463	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06234
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9506
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03269
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17492
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92393
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92795
Familial partial lipodystrophy type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
MFM223	DepMap CRISPR Gene Dependency	1.0	2.48674
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14516
5g3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2394
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1071
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0616
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17065
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.1218
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5627
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.7407
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1746
NZOV9	DepMap CRISPR Gene Dependency	1.0	4.30222
Glycogen storage disease III	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5699
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5834
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72535
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1286
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3529
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65231
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
TC71	DepMap CRISPR Gene Dependency	1.0	5.37243
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.8551
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CJ-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM1S	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14425
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4422
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12897
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31781
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.529
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.0848
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2842
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1284
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.639575
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.8725
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993135
SU8686	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39234
NCIH841	CCLE Cell Line Gene CNV Profiles	1.0	1.64464
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03096
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18626
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7228
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62014
MLMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856831
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.2289
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01055
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9038
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3591
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0829
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00947
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61357
POLR2A	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33405
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20469
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77906
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959706
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.7368
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983788
LS1034	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49799
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.3138
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4881
TE5	CCLE Cell Line Gene CNV Profiles	1.0	2.83641
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76551
IGR37	CCLE Cell Line Gene CNV Profiles	1.0	1.60043
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43504
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64159
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.897932
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90417
SCABER	CCLE Cell Line Gene CNV Profiles	1.0	1.49183
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
MKN74	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57252
SARS-BatSRBD_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64218
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.49373
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.46135
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879296
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9749
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37246
Signaling by GPCR	Reactome Pathways 2014	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8132
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.83252
MZ1-PC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4885
Nucleolus organizer region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947828
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3049
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4007
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5715
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9562
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6124
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26099
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8558
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1265
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2433
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.9803
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.4311
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03934
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1515
WEHI-3B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2752
NCIH510	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36394
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0744
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	110.908
COLO320	DepMap CRISPR Gene Dependency	1.0	5.91858
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.41764
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7744
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
IRF1	ChEA Transcription Factor Targets	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18161
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9936
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13561
HO1U1	DepMap CRISPR Gene Dependency	1.0	2.96037
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5725
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9071
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0819
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959706
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.667647
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4998-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9511
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35126
LS1034	DepMap CRISPR Gene Dependency	1.0	3.03187
496100415_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.43717
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1373
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958653
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10902
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.46421
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54295
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71743
127399	DepMap CRISPR Gene Dependency	1.0	2.78177
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20471
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8479
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4018
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2618
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.0634
LNCaP clone FGC	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885032
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92393
NEDD8	Pathway Commons Protein-Protein Interactions	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0413
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5848
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.42717
EP300	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975042
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.44779
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1539
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7144
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
MEHMO syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7004
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.849
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7837
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900544
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.236
Preterm premature rupture of the membranes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	2.02631
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.336
ICC2	DepMap CRISPR Gene Dependency	1.0	5.09263
K029AX	DepMap CRISPR Gene Dependency	1.0	2.83764
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4086
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959706
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.626
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.707
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5877
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31918
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.89923
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.67417
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.43019
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.5185
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.91677
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.729252
93T449	DepMap CRISPR Gene Dependency	1.0	2.00361
COGN305	DepMap CRISPR Gene Dependency	1.0	3.23525
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.523
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2265
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4844
ACHN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74519
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923371
NCIH2110	DepMap CRISPR Gene Dependency	1.0	2.97625
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.58487
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1061
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
response to stimulus	GO Biological Process Annotations 2015	1.0	null
LB831-BLC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2525
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9199
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9831
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9792
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.3064
Chromosome 2p16.1-p15 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
JHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.4965
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9477
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36524
Olfactory glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.1122
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62014
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03963
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58721
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.12129
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Unnamed_6_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10282
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3763
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6127
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01373
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6884
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3876
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2187
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6599
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83459
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3869
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0531
NSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
SF126	DepMap CRISPR Gene Dependency	1.0	2.04154
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885601
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19054
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.98838
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14516
LPS141	DepMap CRISPR Gene Dependency	1.0	2.25683
Chromosome 2q37 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12799
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26953
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.941
TE4	CCLE Cell Line Gene CNV Profiles	1.0	2.03995
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9583
Parkin_OE_GDS4476_55_human_U87MG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72302
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	2.22936
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WERIRB1	DepMap CRISPR Gene Dependency	1.0	2.88736
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4968-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3319
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872006
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4973-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.469
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.946954
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9046
Borjeson-Forssman-Lehmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.4536
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18735
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.4855
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7633
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_3_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4772
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2239
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957242
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.6687
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.900909
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7799
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.994571
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8656
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25992
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856459
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MPP89	DepMap CRISPR Gene Dependency	1.0	2.35089
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.06002
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.6972
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.7059
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.995448
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.4278
BICR56	DepMap CRISPR Gene Dependency	1.0	3.05298
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59708
SNU46	DepMap CRISPR Gene Dependency	1.0	2.26281
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940512
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25058
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.72923
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.521
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8646
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08751
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4884
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
RT-112	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3587
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06907
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
SBC5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35886
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863932
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.124
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3629
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.4489
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5943
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.174
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6757
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2244
GP5D	DepMap CRISPR Gene Dependency	1.0	9.86931
BICR10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
MM485	DepMap CRISPR Gene Dependency	1.0	2.87732
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2706
membrane	GO Cellular Component Annotations 2015	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9148
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7504
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0227
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.858591
JAK1_knockdown_160_GSE37012	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.06712
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950661
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.76194
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857773
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	2.31041
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01487
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.7803
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4534
TE4	DepMap CRISPR Gene Dependency	1.0	4.39815
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.507
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.8317
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8563
Dyslexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	2.27099
NDUFS6	Pathway Commons Protein-Protein Interactions	1.0	null
YAMATO	DepMap CRISPR Gene Dependency	1.0	3.09626
CH-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15589
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.33943
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
SCABER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938992
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36739
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11662
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9799
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.386
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47404
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827221
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.8528
