association	dataset	threshold value	standardized value
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.69142
59M	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88242
EW-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9211
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00712
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.787
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21535
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.708
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941401
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9886
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43439
Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0325
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63786
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59617
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKRC31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74112
KSR2_knockout_60_GSE17923	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.09692
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67483
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58583
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00797
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97157
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.13113
496100476_TCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11445
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77018
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.17169
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.11323
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50933
biological_process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGALS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
PPARA_Deficiency_GDS2934_632_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5988
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881771
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	1.50999
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3658
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0152
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59097
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7449
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2348
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48057
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.79004
E2F4	ENCODE Transcription Factor Targets	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941401
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3075
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8486
Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7406
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40595
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05982
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868612
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81418
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9521
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19074
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.950703
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4271
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828351
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54772
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40806
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907786
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79382
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14592
HT1080	CCLE Cell Line Gene Expression Profiles	1.0	2.17317
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.901577
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5907
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5902
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0851
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9666
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215653
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12647
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
JHU-011	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A843-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7435
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72464
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemoglobinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44648
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8051
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139540_0_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02895
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68904
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8943
PMC4905481-oncotarget-07-11397-s002.xlsx-CtBP1_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8987
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27449
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.175
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882311
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.8364
Prostate adenocarcinoma_PRAD_TCGA-CH-5789-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.270819
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84589
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00427
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8558
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7508
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.42838
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10742
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.675
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1772
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.989054
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881771
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.72771
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1824
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06878
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862831
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898965
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
CEBPB	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926962
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36833
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5212
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38749
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.637755
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8535
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02937
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF268	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100341_TCx_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39405
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89811
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.064202
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HN-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07758
ALG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52304
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.924606
GSE178714_6_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14592
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.994885
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75242
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95654
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYLK_knockdown_48_GSE14525	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66893
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4624
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02895
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86096
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.39193
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7429-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1	JASPAR Predicted Transcription Factor Targets	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6154
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Supplementary_Table_2B_Contrast_ATF4-def_DMSO_2h_vs_HCT116_DMSO_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6714
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1723
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	0.908346
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921576
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05346
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.15587
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8554
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45302
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80476
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
TECPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20374
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7968
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9164
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73556
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868473
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89997
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914859
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.051
thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.760639
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3374
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4794	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3913
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991553
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9058
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23462
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0577
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.705692
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7631
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6332-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02997
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8257-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.269
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9413
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
496100481_PCx_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3059
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52828
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLD1	CCLE Cell Line Gene CNV Profiles	1.0	1.44886
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.953145
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5297
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828351
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.61617
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.68902
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6693
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49596
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85148
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05982
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2761
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4913
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88062
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A7U6-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3585
HT115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7758
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4902
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83497
Brain Lower Grade Glioma_LGG_TCGA-DU-7011-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58537
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.59701
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06878
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.94594
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914859
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858676
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4299
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3587
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9639
MAFF	ENCODE Transcription Factor Targets	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87796
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.74914
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881771
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.82582
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76554
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Supplementary_Table_2F_Contrast_ATF4-def_IGG_8h_vs_HCT116_IGG_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.37502
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9729
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21255
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2251
ETV7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7622
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.946
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10198
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27865
TNS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74201
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828994
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4167
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44761
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914859
GATA1	ChEA Transcription Factor Targets	1.0	null
ARNT_01_315	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.61123
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8808
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41656
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1477
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6111
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.482
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35636
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRF_KO_GDS3732_148_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868612
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6346
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04125
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6093
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7086
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95175
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22901
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56421
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907786
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97251
Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2796
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.39598
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4729
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562	CCLE Cell Line Gene Expression Profiles	1.0	1.79707
496100360_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15827
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.11283
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88489
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67094
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56534
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34703
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2499
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02776
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7775
GCIY	CCLE Cell Line Gene Expression Profiles	1.0	1.90206
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7476
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881771
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	2.64415
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5541
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
HCT116	CCLE Cell Line Gene Expression Profiles	1.0	3.40793
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hand, foot and mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967663
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991553
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882084
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85829
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Olfactory transduction	KEGG Pathways 2026	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56402
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.65367
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38321
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21933
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67084
hsa-miR-654-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Logical memory (delayed recall) in normal cognition	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12647
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100345_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22898
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.13666
GSE206729_3_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	1.48004
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MR-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981132
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.35822
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21761
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.33806
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.800225
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.644
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05703
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8192
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69453
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.79339
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53_01_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60198
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48027
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7804
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9571
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.747
OVMIU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88062
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.08677
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4	CCLE Cell Line Gene Expression Profiles	1.0	2.29101
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.52762
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3431-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15727
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5796
CTCF	ENCODE Transcription Factor Targets	1.0	null
beta-thalassemia intermedia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7373
klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.156502
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857042
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
CORL23	CCLE Cell Line Gene Expression Profiles	1.0	2.31326
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.42155
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8633
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990966
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11128
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8929
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90822
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02776
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.657976
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03868
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96808
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55003
GSE157894_2_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856273
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53596
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36833
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889836
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5044
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9798
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831554
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93915
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04413
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0782
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.946
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90394
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.787
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03561
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18578
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99349
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IGF1R_druginhibition_47_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.86603
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_01_347	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6062
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05982
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.37271
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77944
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18532
Weibel-Palade body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1192
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33694
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14592
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9346
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39016
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48333
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2692
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868612
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28251
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.81775
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.868
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52737
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
MCAS	CCLE Cell Line Gene Expression Profiles	1.0	1.59763
Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2458
NCIH647	CCLE Cell Line Gene Expression Profiles	1.0	1.45285
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03997
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18736
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28738
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MN-01A-22R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4673
FOXP2	ChEA Transcription Factor Targets	1.0	null
496100583_PCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.23356
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14977
EPHA4_knockout_227_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5594
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0474
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Malignant tumor of pancreas_saliva_GSE14245	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53323
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4332-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6589
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.14877
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFRP5_KO_GDS4988_27_mouse_gonadal white adipose tissue HFD	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.89635
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991553
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.51436
ALK_druginhibition_187_GSE50803	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.41269
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_0Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.07353
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.89778
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22331
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90798
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08747
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05031
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1929
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8074
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0835
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.36353
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04436
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.972711
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68674
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
EI24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66064
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.51892
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50616
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.997977
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872964
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.65126
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.38087
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64515
Response to SSRI (symptom remission)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5447
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20438
all	GWASdb SNP-Phenotype Associations	1.0	0.028713
CORL105	CCLE Cell Line Gene Expression Profiles	1.0	1.84194
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB361	CCLE Cell Line Gene Expression Profiles	1.0	1.53682
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9508
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4999-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGFR_druginhibition_83_GSE27640	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.06881
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8553
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04187
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07598
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41032
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8188
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4868-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.483272
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4181
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70539
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20884
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
E2F2_KD_GDS4094_447_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.93552
Brain Lower Grade Glioma_LGG_TCGA-HT-8111-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_6734_KO_TOP3B_SRP345494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.29179
Prostate adenocarcinoma_PRAD_TCGA-KK-A8II-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62399
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8281
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6487
BHT101	CCLE Cell Line Gene Expression Profiles	1.0	1.57862
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1687
response to stimulus	GO Biological Process Annotations 2015	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.20795
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98989
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02476
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23164
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_5_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.189
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0821
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.62865
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12647
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953663
SERINC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01383
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28494
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10249
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32608
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74726
Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATOH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25892
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92954
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.97395
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3043
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
496100599_TCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89211
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8326
NCI-H460	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1723
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24576
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0585
Fra-1_KO_GDS5078_402_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1729
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5024
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17833
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29965
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4113-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68645
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6655
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.33913
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12534
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MK-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8639
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3436-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4171
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64366
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59326
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Supplementary_Table_2A_Contrast_ATF4-def_control_vs_HCT116_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47901
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49306
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95245
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12766
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2244
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.36059
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.258417
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29269
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.847
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
HCC2814	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06743
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.049543
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36833
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4488
cSARS Bat SRBD_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.65002
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARA_KO_GDS2886_484_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1563
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3376
MKN28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
beta thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.938289
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14653
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.643
CDK8_knockdown_161_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.68538
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7919-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189859,GSE189861_1_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5581
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-2.27211
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36983
GATA1	ENCODE Transcription Factor Targets	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1542
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881771
Alpha thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52893
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1221
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0434
receptor activity	GO Molecular Function Annotations 2015	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7156
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2512
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29251
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953663
Lung squamous cell carcinoma_LUSC_TCGA-77-8139-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924579
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952336
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17068
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6997
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11736
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32496
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95311
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88581
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1685
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3604
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.99918
sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.13628
MYC	ENCODE Transcription Factor Targets	1.0	null
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8883
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64699
signal transduction	GO Biological Process Annotations 2015	1.0	null
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68419
MAFK	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905054
icSARS CoV_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.82597
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75335
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51534
Lung squamous cell carcinoma_LUSC_TCGA-85-8354-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1976
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.27797
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WQ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57689
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02776
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18041
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73072
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4667
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.65247
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0432
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4863
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96339
Response to antidepressants (symptom remission)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
PRKCA_KO_GDS2141_300_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24607
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2323
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03397
Beta thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.809818
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21933
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07858
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04708
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868612
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6303
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952962
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8159
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08865
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91449
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DV90	CCLE Cell Line Gene Expression Profiles	1.0	1.95414
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36519
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.3407
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028737
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
Signaling by GPCR	Reactome Pathways 2014	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14572
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.50982
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06878
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.029
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953663
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86597
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAF1_activemutant_219_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.00745
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.029
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63014
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0457
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6996
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29808
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7828
HLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	1.38586
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6454
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871016
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.80604
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41391
membrane part	GO Cellular Component Annotations 2015	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2772
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36719
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03181
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EM-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7907
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.045164
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9227
METTL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84721
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59097
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5923
Brain Lower Grade Glioma_LGG_TCGA-TM-A84T-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76627
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3277
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18041
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-0.871048
ZFP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90916
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20438
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02936
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15456
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14653
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1522
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0537
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172201_1_v_0_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.754896
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5831
Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.33106
RERFGC1B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45404
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28494
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.895
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79986
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80577
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8049
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.217
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33886
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GN-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PVR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6928
Brain Lower Grade Glioma_LGG_TCGA-DU-7298-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18532
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.273436
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I8-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.91323
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4872
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6542
NCIH747	CCLE Cell Line Gene Expression Profiles	1.0	1.46731
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NL-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41481
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48022
SNU601	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79257
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040265
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.008155
disease	GWASdb SNP-Disease Associations	1.0	0.024768