association	dataset	threshold value	standardized value
GATA1_erythroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.72748
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1691
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9565
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1616
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
PACADD161	DepMap CRISPR Gene Dependency	1.0	5.1645
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.566
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22099
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
Perturb_9749_KO_ORF45_SRP352758	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61777
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.925844
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4828
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44436
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54739
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0521
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1561
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847075
response to stimulus	GO Biological Process Annotations 2015	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Supplementary_Table_2F_Contrast_ATF4-def_IGG_8h_vs_HCT116_IGG_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942566
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	2.87423
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848786
NCI-H146	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6315
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
GSE172201_1_v_0_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882742
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49307
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skmes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2175
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884587
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7429-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44764
MCAS	CCLE Cell Line Gene Expression Profiles	1.0	1.88411
EFO21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89739
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69808
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2376
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1793	CCLE Cell Line Gene Expression Profiles	1.0	1.4737
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54999
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.698
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07876
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6949
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3537
Sensory Perception	Reactome Pathways 2024	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5295
sensory perception	GO Biological Process Annotations 2015	1.0	null
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29787
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
cSARS Bat SRBD_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.42807
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8531
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5007-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999549
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66009
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.816
GSE179138_4_v_1_lama4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9715
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88487
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00155
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52592
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.9312
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.32299
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882742
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03691
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998967
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.89606
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3519
NCIH1568	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46582
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39105
E2F1	ChEA Transcription Factor Targets	1.0	null
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921224
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874955
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.53918
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2122	CCLE Cell Line Gene Expression Profiles	-1.0	-2.51948
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day4_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.55158
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39105
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20879
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03164
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
F36P	DepMap CRISPR Gene Dependency	1.0	7.75315
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.887
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20661
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5391
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.67623
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00291
biological regulation	GO Biological Process Annotations 2015	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.956609
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.757
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32493
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61439
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868831
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75866
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02828
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5879
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GCIY	CCLE Cell Line Gene Expression Profiles	1.0	2.2853
HS683	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06155
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978469
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.61596
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.52288
ECGI10	CCLE Cell Line Gene Expression Profiles	1.0	1.43303
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UROtsa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.32299
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2621
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43109
GSE229973_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03536
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6983
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HTK	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79674
Lung squamous cell carcinoma_LUSC_TCGA-85-8354-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14478
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCAS	DepMap CRISPR Gene Dependency	1.0	3.25939
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-409-SOX18_SOX18	Rummagene Transcription Factor Associations 2026	1.0	null
HCC70	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63728
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4629
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84974
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.7873
Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11089
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76357
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28896
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13986
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.74214
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8688_KD_FAT1_SRP358313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.82954
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845457
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29018
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.88
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03691
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1386
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.37632
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4283
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100454_FWM_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04968
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54516
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Supplementary_Table_2A_Contrast_ATF4-def_control_vs_HCT116_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8724
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7213
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0934
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF1	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3093
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6844-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2149
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3372-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6446
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.958577
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2712
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33467
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.747
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45571
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93817
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY7	DepMap CRISPR Gene Dependency	1.0	5.16015
Breast invasive ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8484
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-79-5596-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5346
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13686_KD_LDB1_SRP398635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Olfactory transduction	KEGG Pathways 2026	1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-ZNF205_ZNF205	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62721
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916668
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.78718
JHUEM2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.6523
oaw28	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2085
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976066
GSE221932,GSE222115_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6734_KO_TOP3B_SRP345494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.41498
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
VMRCLCD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46247
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83212
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76622
system process	GO Biological Process Annotations 2015	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03512
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48059
NCI-H716 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.26083
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60766
GATA2	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3598
HS688AT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56509
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882846
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24129
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.83458
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1964
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7626
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8754
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.7819
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81421
POLR2A	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925174
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAKI1	CCLE Cell Line Gene Expression Profiles	1.0	2.28511
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06573
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8507
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884032
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB231	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64188
SH-EP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5307
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0789
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.548
PMC4905481-oncotarget-07-11397-s002.xlsx-CtBP1_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.08688
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11149
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11089
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43423
Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
CCLFPEDS0008T	DepMap CRISPR Gene Dependency	1.0	2.15904
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Signaling by GPCR	Reactome Pathways 2014	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12267
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.41037
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Response to antidepressants (symptom remission)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Malaria	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9549
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.2778
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.75038
JJN3	DepMap CRISPR Gene Dependency	1.0	3.10201
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56416
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1673
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884032
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT1080	CCLE Cell Line Gene Expression Profiles	1.0	1.54355
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03512
EP300	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	2.21051
CMK115	DepMap CRISPR Gene Dependency	1.0	2.02145
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE203158_0_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.203712
GSE125219,GSE125221_5_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00917
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Supplementary_Table_2B_Contrast_ATF4-def_DMSO_2h_vs_HCT116_DMSO_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Iris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2542
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6755
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14478
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.65226
Perturb_16449_KO_MIR22_SRP277508	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.56239
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.37432
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Iris smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18263
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.35339
HMY1	DepMap CRISPR Gene Dependency	1.0	3.23211
KP2	DepMap CRISPR Gene Dependency	1.0	2.01692
SNU213	DepMap CRISPR Gene Dependency	1.0	2.93358
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09944
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1_01_354	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.06585
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.730598
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834538
biological_process	GO Biological Process Annotations 2015	1.0	null
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27922
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
D458	DepMap CRISPR Gene Dependency	1.0	2.39795
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.652352
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C10	DepMap CRISPR Gene Dependency	1.0	4.08799
TE9	DepMap CRISPR Gene Dependency	1.0	2.03035
Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH209	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47913
H3K36me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6973
DLD1	CCLE Cell Line Gene CNV Profiles	1.0	1.44846
496100603_PCx_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.33351
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884032
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18263
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHOS2	DepMap CRISPR Gene Dependency	1.0	2.34916
Parasitic infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Colo-201 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV MA15_Day1-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.50892
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71018
membrane	GO Cellular Component Annotations 2015	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17738
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986209
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6873
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0026
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
NCI-H2009 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	2.19694
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1512
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.03053
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.98144
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48576
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884032
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60946
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04218
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37615
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1386
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65938
Brain Lower Grade Glioma_LGG_TCGA-HT-8111-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41323
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38323
H3K27me3_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.840017
signal transduction	GO Biological Process Annotations 2015	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9545
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.05685
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41436
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.79619
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2023
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2373
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904199
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7223
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1391
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50834
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15527
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC151	CCLE Cell Line Gene Expression Profiles	1.0	1.49771
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951272
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945554
Perturb_3787_KD_GLI1_SRP042158	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
KS1	CCLE Cell Line Gene Expression Profiles	1.0	1.38881
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48632
PL4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11721
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9672
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3323-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9291
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.74767
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A7TX-01A-33R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0887
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22778
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.54613
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07255
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8346
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03536
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-B_ATF4-def_vs_HCT116_DMSO2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
HEC6	DepMap CRISPR Gene Dependency	1.0	2.02287
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05811
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8654
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882846
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7086-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.36277
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE62843,GSE64370_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-F_ATF4-def_vs_HCT116_IGG8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962619
AM38	CCLE Cell Line Gene Expression Profiles	1.0	1.96677
HT55	DepMap CRISPR Gene Dependency	1.0	4.07318
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91384
Perturb_12628_KD_CYGB_SRP388176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.36247
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903809
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00766
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6907
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CORL105	CCLE Cell Line Gene Expression Profiles	1.0	1.87582
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42068
cSARS Bat SRBD_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.20592
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
RC-K8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.67872
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5376
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02828
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GCT	DepMap CRISPR Gene Dependency	1.0	2.0884
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17717
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK19_knockdown_162_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.45594
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.930273
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.66648
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30493
HUCCT1	DepMap CRISPR Gene Dependency	1.0	2.07479
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.50954
FOS	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7057
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
ZBTB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142588_2_v_3_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0571
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-5.51085
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8216
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
DLX5_Deficiency_GDS4443_355_mouse_E10 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SKLMS1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34252
CAKI2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0751
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.006
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992485
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24617
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201239_6_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07054
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42932
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	1.0	3.95679
Neuroendocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81906
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-OVOL2_OVOL2	Rummagene Transcription Factor Associations 2026	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.05214
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32711
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.414
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10165318-MCO2-4-e258-s001.docx-0-Up_PRP3-KD_vs_PRP3-wt_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39105
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MN-01A-22R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
Fibrillar center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.33009
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1915	DepMap CRISPR Gene Dependency	1.0	2.64718
CORL23	CCLE Cell Line Gene Expression Profiles	1.0	2.03991
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9164
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50064
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884032
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH322	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12281
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8109-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.11298
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2649
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5178
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6798
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.57018
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.70778
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870326
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1484
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92432
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11149
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852823
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4073
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03691
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS746T	DepMap CRISPR Gene Dependency	1.0	3.24896
ncih727	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.647
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HN-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139540_0_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7609-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04258
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2538
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE116299_0_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Parasitic protozoa infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153484_2_v_0_foxp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52461
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2685
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6435
CHLA06ATRT	DepMap CRISPR Gene Dependency	1.0	2.23676
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9274
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Y-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC3	CCLE Cell Line Gene Expression Profiles	1.0	1.61299
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962619
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
developmental	GAD High Level Gene-Disease Associations	1.0	0.293278
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50616
JHH4	CCLE Cell Line Gene Expression Profiles	1.0	1.63586
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79511
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5211
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02828
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.36414
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8116
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Clove	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825603
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.85972
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U8-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7889
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.995
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2997
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5652
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9412
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42812
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33373
TRPV4_DEPLETION_GDS4851_89_mouse_3T3-F442A adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9135
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.372
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.46
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.351
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48928
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4191
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8189
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91158
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0639
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18662
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2174
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03636
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.28859
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845457
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845457
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.7497
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.19605
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.22124
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K029AX	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57999
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2801
SLR21	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08058
GSE209928_0_v_1_kmt2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5_OE_GDS4978_548_human_L428-PAX5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3525
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37302
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845457
SF172	DepMap CRISPR Gene Dependency	1.0	2.18837
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.65347
Inflammation	CTD Gene-Disease Associations	1.0	1.09297
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54954
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01128
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.58491
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.17147
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LI7	DepMap CRISPR Gene Dependency	1.0	4.10613
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958251
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLR23	DepMap CRISPR Gene Dependency	1.0	3.13863
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958251
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22099
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14584
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32651
ATF3_01_33	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6009
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.951812
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75612
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44302
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6709
SW1353	CCLE Cell Line Gene Expression Profiles	1.0	1.73668
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133683_1_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FN-7833-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43672
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36984
cell part	GO Cellular Component Annotations 2015	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.14241
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53423
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.19367
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07396
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.62844
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.9768
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6742
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8962
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
A-Netherlands-602-2009(H1N1)_18Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.13708
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.81745
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.35981
K562	CCLE Cell Line Gene Expression Profiles	1.0	3.40793
sp3_17923686_e12dot5_heart_lof_mouse_gpl1261_gds3058	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.023534
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH358	CCLE Cell Line Gene Expression Profiles	1.0	1.38411
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.05407
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.36819
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00639
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962619
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HCT116	CCLE Cell Line Gene Expression Profiles	1.0	2.19879
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100415_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07219
PANC0203	DepMap CRISPR Gene Dependency	1.0	5.15952
HDAC2	ENCODE Transcription Factor Targets	1.0	null
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7915
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09771
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1473
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.68881
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.80166
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.05
TP63	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Small intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.56
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43191
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7916
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5196-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3325
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88579
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00602
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.59802
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958251
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0636
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980003
9505BIK	DepMap CRISPR Gene Dependency	1.0	2.15373
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4076
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1653
Response to SSRI (symptom remission)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1386
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6471
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.63989
ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71027
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Iris sphincter muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.058
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A	ChEA Transcription Factor Targets	1.0	null
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.7489
TIA1_KO_GSE54418_261_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.69122
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_1_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.869
Foreskin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4994
OE33	DepMap CRISPR Gene Dependency	1.0	4.0071
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6704
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21486
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0369
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93906
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4166
GSE147626_2_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7538
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18662
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03636
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77849
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4999
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.98144
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6647
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2768
LS180	DepMap CRISPR Gene Dependency	1.0	2.19796
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.38004
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.806642
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.36537
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.652352
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0682
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911241
Delta beta-thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
EP300	ENCODE Transcription Factor Targets	1.0	null
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.01432
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.710205
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56893
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
CAKI1	DepMap CRISPR Gene Dependency	1.0	2.89006
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Supraspliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.173
GSE206516,GSE206518_2_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A375	CCLE Cell Line Gene Expression Profiles	1.0	1.56089
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03512
GSE189859,GSE189861_1_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.65106
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1408
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86097
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5055
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867302
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.835
TYK-NU	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2889
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYNCRIP_OE_GDS3186_84_mouse_wild type 129 mouse retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.538
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27902
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12546
20407444-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35636
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09565
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMES1	DepMap CRISPR Gene Dependency	1.0	2.2437
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35135
FOXP3_ABLATION_GDS2525_64_mouse_mature regulatory T cells (Treg)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03204
Epitheloid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67992
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1792
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7469
EZH2	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab10_KDM5C-KD-up-DKD-rescued-Table_10_Up-regulated_genes_in_KDM5C-KD_and_rescued_genes_in_DKD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82772
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945554
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
R1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
SW1271	DepMap CRISPR Gene Dependency	1.0	2.84526
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3093
GATA2	ChEA Transcription Factor Targets	1.0	null
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEYA8	DepMap CRISPR Gene Dependency	1.0	2.12495
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57204
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.413
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35661
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4286
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5418
LCLC103H	DepMap CRISPR Gene Dependency	1.0	3.22172
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11089
PWR-1E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNFI	DepMap CRISPR Gene Dependency	1.0	2.01082
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.861
Logical memory (delayed recall) in normal cognition	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TALL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82661
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0816
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.554
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3403
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19254
efm19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
HLE	CCLE Cell Line Gene Expression Profiles	1.0	1.35886
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0756
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52091
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5630028-supp_gr.220533.117_Supplemental_File_S2_Total_RNAseq_data.xlsx-HCT116_TP53_KO-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37593
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33659
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67472
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1425
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34806
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C5-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47799
H4	CCLE Cell Line Gene Expression Profiles	1.0	1.72975
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76041
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.33822
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30493
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
SCLY	ChEA Transcription Factor Targets	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.03604
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11344
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59318
Mammary ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.925244
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20513
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.696648
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30745
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.51411
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12074
Signal Transduction	Reactome Pathways 2014	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SE-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4189
SARS-CoV MA15_Day2-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.12327
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41704
EFO21	DepMap CRISPR Gene Dependency	1.0	2.02707
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.43555
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02828
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968404
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null