association	dataset	threshold value	standardized value
PMC7029484-13041_2020_561_MOESM3_ESM.xlsx-Table_S8-Table_S8_The_extracted_upregulated_genes_in_SBMA-MNs_in_GSEA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71654
BRD-K68072222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10442
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882304
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39507
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88188
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
androstenone	GeneRIF Biological Term Annotations	1.0	null
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30884
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6042
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1368
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4744
myocardial infarction	GWASdb SNP-Disease Associations	1.0	0.961144
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.43745
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9342
BRD-K16267084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08924
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0315
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.197
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09038
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.722
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9724
L33	DepMap CRISPR Gene Dependency	1.0	2.47168
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.37415
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0164
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2714
RERFLCAI	CCLE Cell Line Gene CNV Profiles	1.0	1.36699
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K26766547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33141
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931144
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23665
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01006
CAL-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53848
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.167208
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35522
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7259_KD_EP300_SRP193326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6031-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10130686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10429
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58070604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32503
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.181
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.10706
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872851
Lymph node carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
NET1_KD_GDS4196_436_human_AGS - gastric adenocarcinoma cells - (63 shRNA Knock-Down)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15218
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00358
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.980143
GSE209601_2_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878804
Mild age-related type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939411
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225647
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8301
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3114
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.65031
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25193
BRD-K42605555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54242
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K68562280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10633
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3752
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07427
receptor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33935
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.6326
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79347397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04253
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2821
abnormality of the biliary system	GWASdb SNP-Phenotype Associations	1.0	0.225826
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.322
ligands	GeneRIF Biological Term Annotations	1.0	null
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0573
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supraspliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
andor	GeneRIF Biological Term Annotations	1.0	null
Prostate epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31105
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
icSARS-Cov_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.60676
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072435
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03724
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.70856
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
malaria	GWASdb SNP-Disease Associations	1.0	1.00221
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4088
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13915
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
preoperative	GeneRIF Biological Term Annotations	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65449
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095927
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29606
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09501
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39843
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K04757670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72156
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5524
cellular response to fatty acid	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3927	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skmes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
arthralgia	GWASdb SNP-Phenotype Associations	1.0	0.881393
KYSE410	DepMap CRISPR Gene Dependency	1.0	6.0775
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6919
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8694
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.97178
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.038
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0029
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.45607
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79826
OV-90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59837
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2159
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5106
BRD-K51298794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24464
BRD-K75853175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1261
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
BRD-K93491540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42706
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7602
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular response to fatty acid	GO Biological Process Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4976
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
early endosome	GO Cellular Component Annotations 2023	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1579
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6354
relative	GeneRIF Biological Term Annotations	1.0	null
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44881
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0599
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2137
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00682
BACH1	ChEA Transcription Factor Targets	1.0	null
positive regulation of blood pressure	GO Biological Process Annotations 2015	1.0	null
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.236
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC8384902-mmc5.xlsx-H889_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47433
BRD-K06116445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10984
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6072
Perturb_5535_KO_GOLGB1_ERP022243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hsa-miR-181a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of blood pressure	GO Biological Process Annotations 2015	1.0	null
BRD-K47510632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28964
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21011
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5008-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A61864215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39661
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.066728
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35315
HCC1395	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61367
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8812
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.58536
GTEX-X4EP-0826-SM-3P5YK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03807
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3163
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K77873562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49378
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
dihydroergotamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93367
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71483
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
vascular disease	GWASdb SNP-Disease Associations	1.0	0.095991
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956885
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.299
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88649
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838826
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE139948_3_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.63036
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30746
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86076
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.099971
CP-319743-7532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05999
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9688
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.60344
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9709
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
hsa-miR-181d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	3.92534
jaundice	GWASdb SNP-Phenotype Associations	1.0	0.881393
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
level	GeneRIF Biological Term Annotations	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870111
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4679
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95347
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852648
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K23333192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45808
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47141
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.311
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21647
DMS-53	GDSC Cell Line Gene Expression Profiles	1.0	1.65964
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3308-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SQ-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.968
NCIN87	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80508
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44424
DB	DepMap CRISPR Gene Dependency	1.0	2.33154
BRD-K87290989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01227
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
nausea	GWASdb SNP-Phenotype Associations	1.0	0.881393
MCAS	DepMap CRISPR Gene Dependency	1.0	2.23053
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10204296-13578_2023_1034_MOESM16_ESM.xlsx-Black-ZNF671_ZNF671	Rummagene Transcription Factor Associations 2026	1.0	null
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14107
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11447
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.45641
BRD-K06725890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00736
BRD-K47998973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16215
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71449
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48052
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42481
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053499
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.411218
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850015
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32715
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27748
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X0-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91459693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44532
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45683
RBM22_02_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.90689
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34239
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3978
positive regulation of renin secretion into blood stream	GO Biological Process Annotations 2023	1.0	null
Prostate gland epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.3218
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01907
hsa-miR-3915	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90676
positive regulation of blood circulation	GO Biological Process Annotations 2015	1.0	null
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1731
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49249
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLD1	CCLE Cell Line Gene CNV Profiles	1.0	1.44433
BRD-K47572485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60309
hsa-miR-3158-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1664
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05677
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.109032
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945894
BRD-K20024676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00546
BRD-K05229696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6196
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075766
BRD-K01717817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09796
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11261
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.773
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K98005735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61713
BRD-K25710391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04297
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Chemical And Drug Induced Liver Injury	DisGeNET Gene-Disease Associations	1.0	null
SKRC31	CCLE Cell Line Gene Expression Profiles	-1.0	-3.02767
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K37071891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00516
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45442
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21789048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47128
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5455
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3336
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911168
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49513
BRD-K45380779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39711
CRCGN015_MCF10A_48H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25777
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34626
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8107
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7376
BRD-K48782834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07897
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.005
Ground meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
BRD-K93339508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02068
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5336
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17208
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15417
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968819
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975526
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25196
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20142
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6066
while	GeneRIF Biological Term Annotations	1.0	null
BRD-K26631178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16852
CRCGN015_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51801
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5383
Huh-7.5.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
hsa-miR-4262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Perturb_17454_KO_Insr/Igf1r_SRP091479	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.64263
HS255T	CCLE Cell Line Gene Expression Profiles	1.0	1.42992
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16258
BRD-K95023134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29326
MAFK	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51252
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.14431
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40101
RCOR1	ChEA Transcription Factor Targets	1.0	null
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3429
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039551
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89477
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	4.89999
BRD-K65934178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16422
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.75352
COLO-320-HSR	GDSC Cell Line Gene Expression Profiles	1.0	1.42154
BRD-K24838542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20187
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4768-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.895351
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6545
BRD-K97784715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85652
abnormal telencephalon morphology	MPO Gene-Phenotype Associations	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
retinal coloboma	GWASdb SNP-Phenotype Associations	1.0	0.881393
Embryonic germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.26419
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.02171
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRD-K62708569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2079
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VO-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
malaria	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
BRD-K91796483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35288
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	2.55005
ikarugamycin-918	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN011_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02495
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.120414
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14485
colon_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.09582
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87568
early endosome	GO Cellular Component Annotations 2025	1.0	null
BRD-K60578515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01642
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.73248
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59634
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.071215
SHP77	CCLE Cell Line Gene Expression Profiles	1.0	2.25276
BRD-K87666020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02489
higher	GeneRIF Biological Term Annotations	1.0	null
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17958
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17601
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15476
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.962718
hsa-miR-514b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08187
BRD-K66621600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08484
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.324
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5654
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.37112
ADNP_Deficiency - NULL MUTATION_GDS2540_692_mouse_E9 embryos - Homozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A94366206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31298
prostate epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.97935
Prostate adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.314
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0505
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00301
hemoglobinuria	GWASdb SNP-Phenotype Associations	1.0	0.881393
blood vessel	GTEx Tissue Gene Expression Profiles	1.0	1.00392
anemia	GWASdb SNP-Phenotype Associations	1.0	1.33719
BRD-K41809257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09165
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070992
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
regulate	GeneRIF Biological Term Annotations	1.0	null
SUM149PT	DepMap CRISPR Gene Dependency	1.0	2.23976
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.69583
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5902
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65245206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65053
positive regulation of blood pressure	GO Biological Process Annotations 2025	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.66274
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	4.54879
hsa-miR-3692	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K11331752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39914
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09585
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.111675
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.290652
hsa-miR-1303	MiRTarBase microRNA Targets	1.0	null
positive regulation of renin secretion into blood stream	GO Biological Process Annotations 2015	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.048913
BRD-K03925537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14721
GTEX-NFK9-2026-SM-3LK5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31606
NCIH2081	CCLE Cell Line Gene Expression Profiles	1.0	1.52397
regulation of renal system process	GO Biological Process Annotations 2015	1.0	null
BRD-K13852343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26885
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2686
hsa-miR-4691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.0799
LAN2	DepMap CRISPR Gene Dependency	1.0	5.94788
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
YY2_KD_GDS3788_490_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18051
MDAMB361	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47678
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-K63743653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37191
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.12
EZH2	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57292
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1088
ACLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0040549
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01224
BLUE1	DepMap CRISPR Gene Dependency	1.0	6.14381
regulation of system process	GO Biological Process Annotations 2015	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1277
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.866
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0993
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K95018971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13193
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.8418
BRD-K91202220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54582
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94946
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.98847
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1586
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59403
BRD-K00010082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34331
BRD-A15798299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49318
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.862037
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.69962
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	3.77638
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03342
Perturb_17775_OE_Tgfb1_SRP325964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70241
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.994554
EPHA4_drugactivation_229_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.48442
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5581
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.746
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35471
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31713
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059872
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.535796
BRD-K51364219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07887
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4789-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25538
HOXC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97333
EGR-1_KO_GDS3607_525_mouse_Retina - 30 Days (POST-NATAL)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K03554945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6553
BRD-K45888106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41511
BRD-K59744424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58379
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.10706
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17601
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35887
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1263	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45889
HCC1937	DepMap CRISPR Gene Dependency	1.0	2.54307
Early endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47894
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-WL-A834-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60085
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.577
lung	GTEx Tissue Gene Expression Profiles	-1.0	-0.844911
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.025
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cases	GeneRIF Biological Term Annotations	1.0	null
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32911
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	2.29696
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0191
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.831895
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
BRD-K27161987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17432
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833806
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8065
Prostate adenocarcinoma_PRAD_TCGA-EJ-7218-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12967
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14859
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
Low Grade Prostatic Intraepithelial Neoplasia	DisGeNET Gene-Disease Associations	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Drug-Induced Liver Disease	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32575
Perturb_7001_KO_Acadl_SRP323582	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.1271
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8101
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.561004
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9738
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.068488
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43443
regulation of cellular localization	GO Biological Process Annotations 2015	1.0	null
Prostatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
Signaling by GPCR	Reactome Pathways 2014	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2862
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.577615
BRD-K30799912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54197
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5313
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7043
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2044
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88188
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
prostate gland epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
regulation of establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K90821428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21892
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM278	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01039
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6585
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MGA_MGA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963697
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24505
cellular response to organic substance	GO Biological Process Annotations 2015	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06225
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04293
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858354
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.278
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.62385
DU-145 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09493
parasitic protozoa infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21653
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13989
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
anemia due to reduced life span of red cells	GWASdb SNP-Phenotype Associations	1.0	0.403982
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041318
hsa-miR-4672	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9274
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
regulation of secretion	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29527
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616183
headache	GWASdb SNP-Phenotype Associations	1.0	0.881393
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953505
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6178
BRD-K53647637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3065
Prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.932
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.37598
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4146
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043095
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19978
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-A96791331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16344
GSE255432_7_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4862
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893105
MFE-280	GDSC Cell Line Gene Expression Profiles	-1.0	-2.24721
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70678
transcriptional	GeneRIF Biological Term Annotations	1.0	null
VCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22819
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K69089961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30521
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16263
MHHES1	DepMap CRISPR Gene Dependency	1.0	2.95387
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38349
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WH7G-1326-SM-4LVMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16431
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K75331656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26193
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57433
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.965
membrane	GO Cellular Component Annotations 2015	1.0	null
GSE119978,GSE180930_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4675
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5204
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
BRD-K56161792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01576
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
coloboma	GWASdb SNP-Phenotype Associations	1.0	0.881393
BRD-K89397494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09687
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14833
hsa-miR-4540	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SNU16	DepMap CRISPR Gene Dependency	1.0	4.18059
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36253
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.24115
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.042
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392309
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040457
ACC3	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.939592
PACADD188	DepMap CRISPR Gene Dependency	1.0	3.68305
BRD-K58220566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18237
BRD-K14359826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32264
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K33734659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44816
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849232
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8503
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.194
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Floral meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07653
Prostatic Intraepithelial Neoplasias	DisGeNET Gene-Disease Associations	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.9608
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4685
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.139
NCI-H2452	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43323
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5144
gabexate-4220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain_CT2_Exc L3-5 FEZF2 ASGR2	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51375
CRCGN008_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1915
colon	GTEx Tissue Gene Expression Profiles	1.0	1.06804
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.846692
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3459
SYK_KD_GDS3609_440_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-XAJ8-0326-SM-47JYI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827036
BRD-K87875370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04543
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824419
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
elevated	GeneRIF Biological Term Annotations	1.0	null
response to chemical	GO Biological Process Annotations 2015	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
EC-GI-10	GDSC Cell Line Gene Expression Profiles	1.0	1.46188
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DUSP1_KO_GDS1606_775_mouse_Spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VERO C1008 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
stage	GeneRIF Biological Term Annotations	1.0	null
abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.128145
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47509
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0011
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
steroid hormone mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10985
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.19475
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5836
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
prostate	GTEx Tissue Gene Expression Profiles	1.0	1.94274
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071877
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51552
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7518
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29277
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.487
regulation of protein secretion	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59997
Prostate epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.81
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9679
prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.55712
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4227
hsa-miR-4676-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0427
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884042
BRD-K44624253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30774
BRD-K89232006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1661
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69372
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24918
normocytic anemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.602429
Sympodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
abnormality of the liver	GWASdb SNP-Phenotype Associations	1.0	0.134151
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944365
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05228
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60536
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.095841
some	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20075
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS-445	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.65
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87554792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14196
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.40611
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
IRF4	ENCODE Transcription Factor Targets	1.0	null
BEN	CCLE Cell Line Gene Expression Profiles	1.0	3.40927
NCIH810	CCLE Cell Line Gene Expression Profiles	1.0	1.38096
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903949
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.06156
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26961
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83125173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06877
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.34225
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1926-SM-4BOP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11862
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22636
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052095
NCI-H2029	GDSC Cell Line Gene Expression Profiles	1.0	2.00883
Prostate adenocarcinoma_PRAD_TCGA-HC-7075-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.141009
BRD-K64483847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01283
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
cellular response to lipid	GO Biological Process Annotations 2015	1.0	null
BRD-K87268607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49901
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.989306
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34572
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71777
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38685
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071441
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7206
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36099
positive regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
CD24_Reduced expression_GDS1392_93_human_Bone Marrow	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K73769678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06138
Huh-7.5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892775
Ec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90055
genetic disease	GWASdb SNP-Disease Associations	1.0	0.453875
BRD-K19817946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4187
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838391
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44793
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.36241
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7591
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21156
ACHE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00416563
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.18474
pathologic	GeneRIF Biological Term Annotations	1.0	null
endosome membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-XBED-2426-SM-4AT4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02193
signal transduction	GO Biological Process Annotations 2015	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FTC133	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46974
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Cirrhosis, Experimental	DisGeNET Gene-Disease Associations	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949734
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07379
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.331025
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18801
hsa-miR-579	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.230478
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.602429
abnormal olfactory bulb development	MPO Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_3H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02208
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3019
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10794
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9733
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2023	1.0	null
OP-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
BRD-K84738609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30667
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.867263
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
steroid hormone receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580017
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.769164
BRD-K38358574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11595
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41874
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387027
BRD-K25161864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23557
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.594
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98378
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950634
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0154
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1883
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.012
olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.930621
BRD-K71574401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72529
BRD-K44133102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63499
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.13316
EFE184	DepMap CRISPR Gene Dependency	1.0	7.40545
abnormal olfactory bulb morphology	MPO Gene-Phenotype Associations	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.14054
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
GTEX-R55G-0426-SM-48FDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00893
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7421
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965579
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74037
hsa-miR-3690	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MM160113	DepMap CRISPR Gene Dependency	1.0	3.08923
BRD-K45941986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02288
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078689
Internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.108
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.161484
APEH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883969
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
psgr	GeneRIF Biological Term Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6556
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3661
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01516
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
early endosome membrane	GO Cellular Component Annotations 2023	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30557
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
QGP1	CCLE Cell Line Gene Expression Profiles	1.0	1.8548
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.51422
rectum_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.937102
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43304
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61468
Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.913698
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.069847
erythroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.427636
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-PCa-2b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02313
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24483
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9705
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76294510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.422
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8766
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33543
BRD-K56658444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56825
BRD-K71357636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11526
kidney disease	GWASdb SNP-Disease Associations	1.0	1.11485
anemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.602429
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.306
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4905-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05563
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52967
prostate	HPA Tissue Gene Expression Profiles	1.0	2.06641
BRD-K68758594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02408
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32057
NCIH1618	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15064
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03629
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.122
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.750656
GSE144796_1_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9764
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61226
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864311
BRD-K07414059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.436
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17097
Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39065
17177833-Table2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K46936325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07671
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61484
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18051
cancers	GeneRIF Biological Term Annotations	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5187
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.509
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.13472
GTEX-XAJ8-0726-SM-47JY5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883311
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35307
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946788
BRD-K64194889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1913
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02408
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.57882
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.913
Drug-Induced Acute Liver Injury	DisGeNET Gene-Disease Associations	1.0	null
SNU1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90811
BRD-K90366266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17086
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5245
il6	GeneRIF Biological Term Annotations	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0424
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24992
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07388
SNU201	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95592
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040851
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
NCIH2227	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97895
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36341
Olfactory placode cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6677
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30557
BRD-K09432998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10212
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07308
GSE178255_2_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
serum	GeneRIF Biological Term Annotations	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01039
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2167
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88148
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44416
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12046
KARPAS-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H510A	GDSC Cell Line Gene Expression Profiles	1.0	2.66461
VMRCLCD	CCLE Cell Line Gene Expression Profiles	1.0	1.75518
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03926
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04774
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1359
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5174
BRD-K67980271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22701
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4915
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23825
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.225826
hsa-miR-3140-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Bipolar Disorder_frontal cortex_GSE5389	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53233
ICC2	DepMap CRISPR Gene Dependency	1.0	4.33735
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03342
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950634
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F2	ChEA Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26336
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.411218
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07329
gastrointestinal inflammation	GWASdb SNP-Phenotype Associations	1.0	0.881393
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3821
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61078510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05245
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995021
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82773
BRD-K81199760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23169
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879979
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6072
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42571
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939865
Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMC-11	GDSC Cell Line Gene Expression Profiles	1.0	2.40441
Chemically-Induced Liver Toxicity	DisGeNET Gene-Disease Associations	1.0	null
abnormal olfactory bulb development	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-3938	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Z8-0726-SM-4GICB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934626
hsa-miR-3152-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
15342375-Table1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_9742_KO_Fxr_SRP241086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.47225
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1_KD_GDS4962_465_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PDE7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91809
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9281
hsa-miR-181c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal recessive disease	GWASdb SNP-Disease Associations	1.0	1.17176
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57427
response to organic substance	GO Biological Process Annotations 2015	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.2846
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45828
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.04317
colonrectum_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.996955
PC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.321
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10965
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21624
RB1_KD_GSE50532_627_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE246195,GSE246305_4_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Perturb_15395_KD_RB1_SRP271262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
chr11_4672440_C_T_b38	GTEx eQTL 2025	1.0	1.02351
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935872
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.050211
most	GeneRIF Biological Term Annotations	1.0	null
T84	DepMap CRISPR Gene Dependency	1.0	3.2187
PMC8786145__F2	PFOCR Pathway Figure Associations 2024	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935093
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52368
PPARA_agonist activation_GSE17250_475_mouse_Isolated hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8612
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5766-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201042_6_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17821
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Floral primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836238
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33497830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21612
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03878
regulation of protein localization	GO Biological Process Annotations 2015	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular response to steroid hormone stimulus	GO Biological Process Annotations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0769
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
BRD-K27256143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12687
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981315
BRD-K22915992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15137
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5715
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05192
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0266
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72439
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11204
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854353
D283MED	DepMap CRISPR Gene Dependency	1.0	3.43523
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7686
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bolting stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908363
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5121-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K42400758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43831
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23038
regulation of protein transport	GO Biological Process Annotations 2015	1.0	null
WICH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00177
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14073
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6558
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.6086
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	2.3892
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57304
CRCGN016_MCF10A.TP53.M_24H:N06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14386
BRD-K48350747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25528
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4907-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4726-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
regulation of blood circulation	GO Biological Process Annotations 2015	1.0	null
nuclear steroid receptor activity	GO Molecular Function Annotations 2025	1.0	null
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7227
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18051
BRD-K32205799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11288
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.172121
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
functional abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.244318
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01143
Intestinal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.27536
KNS60	CCLE Cell Line Gene Expression Profiles	1.0	1.38278
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01978
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-382	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.023
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
BRD-K23316938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59168
BRD-K03371288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07254
Human - Motor Cortex - Cluster - FEZF2+ LINC01107+ Layer 3-5 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
positive regulation of blood pressure	GO Biological Process Annotations 2023	1.0	null
GTEX-RVPU-1526-SM-47JXQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916959
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.901305
Glycated hemoglobin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
496100670_TCx_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32348
Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
ONDA9	DepMap CRISPR Gene Dependency	1.0	2.85939
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-1326-SM-48U1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91146
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951385
BRD-K48764596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0039
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054509
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
cholestasis	GWASdb SNP-Phenotype Associations	1.0	0.881393
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3073
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9683
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32575
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
generalized abnormality of skin	GWASdb SNP-Phenotype Associations	1.0	0.164748
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4999-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994302
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01143
BRD-K98216700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37844
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MPP89	DepMap CRISPR Gene Dependency	1.0	4.71475
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39675
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5312
SHI1	DepMap CRISPR Gene Dependency	1.0	3.55555
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.51
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41765
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2163
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2518
FMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544203
regulation of renin secretion into blood stream	GO Biological Process Annotations 2015	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14484
LAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
BRD-K35347834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31672
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.564
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63663384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14578
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81927
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36579
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4553
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26409
NCIH69	CCLE Cell Line Gene Expression Profiles	1.0	1.55033
BRD-K87176777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22427
BRD-K22564762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14874
Flower stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975244
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4182
side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.141921
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07056
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08018
hsa-miR-380	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56301
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23053
BRD-K41009039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4091
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.794
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.79509
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57595
BRD-K37949240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49431
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09086
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nausea and vomiting	GWASdb SNP-Phenotype Associations	1.0	0.486267
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7354
Human - Motor Cortex - Cross-Species Cluster - Layer 5 glutamatergic neuron, extratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88188
Sarcoma_SARC_TCGA-DX-A3U9-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18935
BRD-K95615652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26355
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02072
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68615
BRD-K88812688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24733
Perturb_12548_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.41614
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7974
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71207
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885628
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2053
RAGE_knockout_269_GSE22873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53078
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052421
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1299	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53773
GSE109285_3_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7939
Sarcoma_SARC_TCGA-KD-A5QU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.698
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11935
hsa-miR-670	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K26291134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50625
GSE110038,GSE133995_3_v_0_hic1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211744_8_v_5_gdf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94275706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01313
NCI-H716 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
CMK	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32352
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904909
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Leaf primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
KARPAS299	CCLE Cell Line Gene Expression Profiles	1.0	1.41262
BEN	GDSC Cell Line Gene Expression Profiles	1.0	1.93797
syncope	GWASdb SNP-Phenotype Associations	1.0	0.881393
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833806
abnormality of urine homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.881393
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6631
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60048
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abdominal symptom	GWASdb SNP-Phenotype Associations	1.0	0.380171
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75146
hsa-miR-4780	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
NCI-H345	GDSC Cell Line Gene Expression Profiles	1.0	1.85734
HT29	DepMap CRISPR Gene Dependency	1.0	2.09572
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.64089
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72585
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7105
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897956
BRD-K95815724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34674
BRD-K08416880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75702
GSE211744_8_v_0_gdf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25862
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.44625
hsa-miR-181b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7818
overexpression	GeneRIF Biological Term Annotations	1.0	null
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05534
prostate gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1744
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-513b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24228
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63712
NU-DUL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87929769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50061
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94372
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64206
BRD-K16826019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19996
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846864
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K66823946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18294
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18134
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040554
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6848
abnormal pulmonary respiratory rate	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_MCF10A.TP53.M_24H:H20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06255
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24918
dermatological manifestations of systemic disorders	GWASdb SNP-Phenotype Associations	1.0	0.881393
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.720345
BRD-K48691513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13424
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836111
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.141009
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	1.40246
PMC11769652-EHF2-12-250-s001.xlsx-Sheet1-ZEB1_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.979951
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46545
cellular response to acid chemical	GO Biological Process Annotations 2015	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.052756
hsa-miR-4685-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8236
NCIH526	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52752
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911533
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.541217
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2496
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ncnc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4068
Neuroendocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24342
Slime layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3218
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4659
BRD-K56939159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87161
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50044
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836335
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11598
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898414
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22819
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.80198
cellular response to oxygen-containing compound	GO Biological Process Annotations 2025	1.0	null
NCIH1755	CCLE Cell Line Gene Expression Profiles	1.0	1.35355
CBX2	ENCODE Transcription Factor Targets	1.0	null
BRD-K36941678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05121
substantially	GeneRIF Biological Term Annotations	1.0	null
HCC44	DepMap CRISPR Gene Dependency	1.0	2.00901
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.100976
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
melanocyte differentiation	GO Biological Process Annotations 2025	1.0	null
BRD-K39668479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23214
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.222
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9884
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
abnormal olfactory lobe morphology	MPO Gene-Phenotype Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0867
Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29969800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39545
BRD-K88357881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64882
DMS53	CCLE Cell Line Gene Expression Profiles	1.0	1.68014
extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.346829
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48429
cellular response to chemical stimulus	GO Biological Process Annotations 2015	1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
OC-314	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46051
ESO51	DepMap CRISPR Gene Dependency	1.0	2.67613
ncih727	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8317
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09332
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91529
percentage	GeneRIF Biological Term Annotations	1.0	null
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3159
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.313
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29831
BRD-K48528697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39912
CRCGN015_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.871
Prostate adenocarcinoma_PRAD_TCGA-HC-8259-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41015
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971005
cellular response to steroid hormone stimulus	GO Biological Process Annotations 2025	1.0	null
hsa-miR-3924	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NCIH157DM	DepMap CRISPR Gene Dependency	1.0	3.22332
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21968
early endosome membrane	GO Cellular Component Annotations 2025	1.0	null
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.184
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13359
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TT-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
Perturb_16364_KO_Cryab/Hspb2_SRP055864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93453
CRCGN013_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4745
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.058037
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3313
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34124
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64635
response to fatty acid	GO Biological Process Annotations 2023	1.0	null
hsa-miR-4501	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
BRD-K33986892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87401
positive regulation of protein secretion	GO Biological Process Annotations 2023	1.0	null
prostatespecific	GeneRIF Biological Term Annotations	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJWN-0626-SM-3NMAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98388
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216672
BRD-K21000135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30616
BRD-K29028138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30906
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7634
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884695
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the urinary system physiology	GWASdb SNP-Phenotype Associations	1.0	0.244318
celiac disease	GWASdb SNP-Disease Associations	1.0	0.601018
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03245
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89054
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71357
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02696
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28636
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09093
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4039
response to fatty acid	GO Biological Process Annotations 2025	1.0	null
hsa-miR-190b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.252
P31-FUJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48299
PACADD165	DepMap CRISPR Gene Dependency	1.0	3.50088
regulation of cAMP-mediated signaling	GO Biological Process Annotations 2023	1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.29053
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Human - Motor Cortex - Cluster - FEZF2+ ASGR2+ Layer 3-5 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1104
BRD-K65135171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01646
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.73649
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.37029
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18031793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05045
BRD-K91271834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40546
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08201
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834348
BRD-K68036990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07509
Prostate-luminal cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	6.47579
GTEX-S3XE-1326-SM-4AD4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29081
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.143
vomiting	GWASdb SNP-Phenotype Associations	1.0	0.881393
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42986
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7522
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K87742870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09205
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0447
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21259
Seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912407
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062592
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892349
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03342
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37538
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1135
Prostate adenocarcinoma_PRAD_TCGA-VP-A87J-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01278504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14343
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5041
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068612
Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-2.36519
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22711
BRD-K80945184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76044
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3187
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.6551
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973617
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880841
regulation of endocrine process	GO Biological Process Annotations 2015	1.0	null
BRD-K72821236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09211
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-190	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K89459607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14389
melanocyte proliferation	GO Biological Process Annotations 2025	1.0	null
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.553
PMC12756533-mmc1.pdf-39-PROX1-AS1_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89679
Acute Myeloid Leukemia_LAML_TCGA-AB-2940-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.415
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5568-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
positive regulation of protein secretion	GO Biological Process Annotations 2025	1.0	null
regulation of renin secretion into blood stream	GO Biological Process Annotations 2025	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
KASUMI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32412
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.07478
GTEX-XUYS-0426-SM-47JX3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15352
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950634
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9995
BRD-A58803929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47892
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.3048
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
BRD-K79213964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0235
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00564
RERF-LC-AI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91905
BRD-K63616423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17715
496100296_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18385
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fetal Hemoglobin Determination	DisGeNET Gene-Phenotype Associations	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.421
SARS-CoV_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64309
abnormal forebrain morphology	MPO Gene-Phenotype Associations	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	1.0	2.65488
PMC9509630__F1	PFOCR Pathway Figure Associations 2024	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82884
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9506
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38598
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76969
PMC4872073-supp_gkv1528_nar-02930-x-2015-File004.xlsx-Table_S2C-CREB1_FoxA1_Target_Genes_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-2926-SM-4B66G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957853
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845299
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.837795
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37245
HS571T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85914
response to fatty acid	GO Biological Process Annotations 2015	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.6461
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09392
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.706812
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01696
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895284
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43984
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6464
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.210472
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.21328
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5112
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07985
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
Type III polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
cellular response to lipid	GO Biological Process Annotations 2023	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10197
Rosette leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of renin secretion into blood stream	GO Biological Process Annotations 2025	1.0	null
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.5
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63431
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8881
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9409
GSE193993_5_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82836
BRD-K13336710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02325
BRD-K00717406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51561
BRD-K45231869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0425
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5748-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.75227
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614167
BRD-K38615358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10856
BRD-K04928505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81128
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06267
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.602429
derivatives	GeneRIF Biological Term Annotations	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81318
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5721
BRD-K20355073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61067
19265129-Table1	GeneSigDB Published Gene Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
BRD-K24443173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04041
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9557
BRD-K85112460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34089
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate	GeneRIF Biological Term Annotations	1.0	null
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7212
positive regulation of secretion	GO Biological Process Annotations 2015	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
SNB75	DepMap CRISPR Gene Dependency	1.0	3.29279
SUSA	DepMap CRISPR Gene Dependency	1.0	2.49475
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917894
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71265
GTEX-OHPL-1826-SM-2YUN8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955616
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14865
HEC-1-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.063008
abnormal nervous system development	MPO Gene-Phenotype Associations	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870777
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GTEX-TKQ1-1226-SM-4GICJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989634
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831095
hsa-miR-194	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:H12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08845
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03835
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E8-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827115
BRD-K52391588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.06031
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89212
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9194
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49895
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.126581
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate gland intraepithelial neoplasia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.71
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5807
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WQ-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8873
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34626
hsa-miR-3164	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.746
496100422_TCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20679
ESRRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00372327
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22253
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5435
JUND_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7071-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25211
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75G-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069019
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
16042785-tableS4	GeneSigDB Published Gene Signatures	1.0	null
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
RERFGC1B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55901
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57988
BRD-K95740363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57761
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59345
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28791
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65235
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86463534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0387
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856333
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.510564
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53252
BRD-K68869896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60054
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.10481
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39455
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.85828
BRD-K22651517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10408
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.184
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14744
cellular response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
PDX1_KO_GDS4348_360_mouse_Proximal small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5497
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.282
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04578
Embryonic brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.46543
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7117
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0014
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular response to lipid	GO Biological Process Annotations 2025	1.0	null
positive regulation of protein secretion	GO Biological Process Annotations 2015	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Parasitic infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.746
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79613
Male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.132
BRD-K21610715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98086
BRD-K18117162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07046
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843773
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02555
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31346
GAMG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65498
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.20481
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10794
NCIH1092	DepMap CRISPR Gene Dependency	1.0	2.03359
NCI-H2009 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	1.07947
BRD-K80602847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20947
Colonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.139
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09699
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-Epithelial_B-pEpi13_B_shared_FU1_ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53073
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35631
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71765
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.961144
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3964
Prostate adenocarcinoma_PRAD_TCGA-G9-7522-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833151
Early endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88188
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.839091
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.90811
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.881576
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.769
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
AR	ChEA Transcription Factor Targets	1.0	null
extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.234174
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831687
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2792
KRAP_Deficiency_GDS3528_564_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SH10TC	DepMap CRISPR Gene Dependency	1.0	7.62845
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03499
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4908-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL30	DepMap CRISPR Gene Dependency	1.0	2.42212
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7084
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883084
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26855
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7889
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934073
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of localization	GO Biological Process Annotations 2015	1.0	null
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18594
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31374
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27826
GTEx Nerve 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-4.07648
hemolytic anemia	GWASdb SNP-Phenotype Associations	1.0	0.881393
PMC2742312-1479-7364-3-3-221-S3.PDF-222-ZNF195_ZNF195	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.903
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21259
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22121
LNZ308	DepMap CRISPR Gene Dependency	1.0	2.41271
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.60474
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053407
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K71941064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44438
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8395
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47675
abnormal brain morphology	MPO Gene-Phenotype Associations	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869847
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63398
cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.346829
sickle cell anemia	GWASdb SNP-Disease Associations	1.0	1.49392
immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.602429
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94404
TGFB2_KD_GDS4483_351_mouse_Embryonic palatal tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27389
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870111
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05453
CAL-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XOTO-0426-SM-4B66A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29061
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24852
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
recombinant	GeneRIF Biological Term Annotations	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.133232
BRD-K40221630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05328
beta thalassemia	GWASdb SNP-Disease Associations	1.0	1.49392
GTEX-S4P3-1226-SM-4AD4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20647
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12135
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911168
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07192
Hepatitis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K32146668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6964
BRD-K59960811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87499
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77442
BRD-K12988428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05268
regulation of renin secretion into blood stream	GO Biological Process Annotations 2023	1.0	null
HCC-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIAS1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69537
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12137
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.48336
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060592
Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.78756
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049361
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-10.7721
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39783
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7523
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K25868508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55015
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2391
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7588
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9951
prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10846
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4428	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05159
HCC1897	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50861
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80722
hsa-miR-1228	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68988
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
melanocyte differentiation	GO Biological Process Annotations 2023	1.0	null
BRD-K88820027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06765
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20715
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06143
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22286
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28484
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K45714931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13939
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.61341
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09392
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834348
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.410414
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19596
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910374
hsa-miR-1271	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
LNCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.89
CRCGN015_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07805
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58892587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07029
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08672
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	3.5201
heterotrimeric g-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.346829
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38405
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.98224
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1187	DepMap CRISPR Gene Dependency	1.0	2.9267
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5891
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8174
extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.255834
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4961-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE264010_0_v_1_parp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59892
BRD-K07624584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17961
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3774
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95691
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46409
BRD-K70286959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2417
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58611
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051548
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13434
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.249571
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3653
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.53159
BRD-K39592958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23592
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3268
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09392
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21259
BRD-K39020351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30881
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43947
fever	GWASdb SNP-Phenotype Associations	1.0	0.881393
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.0942
intraepithelial	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57532
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	2.40869
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051649
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832325
NHEK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24977
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06823
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.521572
abnormal brain development	MPO Gene-Phenotype Associations	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63752
BRD-K51253991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15488
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
9505BIK	DepMap CRISPR Gene Dependency	1.0	5.87702
psgr2	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21891
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88188
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.736
Parasitic protozoa infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.746
pb88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.288
hsa-miR-3617	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U-118-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914283
BRD-K14041149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43525
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.244318
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7629
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LS-1034	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87261428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72855
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24405
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066942
Prostate adenocarcinoma_PRAD_TCGA-EJ-5504-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354455
LNCaP-C4-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828794
CRCGN008_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1488
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.45303
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1516
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.009
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7612
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39535
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of transport	GO Biological Process Annotations 2015	1.0	null
placenta	HPA Tissue Gene Expression Profiles	1.0	0.909863
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-A31602150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40664
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906517
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
steroid hormone receptor activity	GO Molecular Function Annotations 2015	1.0	null
cellular response to fatty acid	GO Biological Process Annotations 2025	1.0	null
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
steroid hormone mediated signaling pathway	GO Biological Process Annotations 2023	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880841
Malaria	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.746
parasitic infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04878
autosomal genetic disease	GWASdb SNP-Disease Associations	1.0	0.489747
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7901
prostate gland epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1981
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
endosome membrane	GO Cellular Component Annotations 2025	1.0	null
PMC9860384-mmc2.xlsx-Table_S4-Table_S4_2016_VCF_Shared_Variants_related_to_the_results_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Nerve 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-5.86704
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43324
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836749
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5512
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.799
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76708
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	1.90044
monogenic disease	GWASdb SNP-Disease Associations	1.0	0.470385
Prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16397
BRD-K28030757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13454
Perturb_16956_Mut_Kif1b_SRP094648	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.61439
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
BRD-K13941052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36774
PNT-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890565
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88748
COLO-668	GDSC Cell Line Gene Expression Profiles	1.0	1.76733
GTEX-S7PM-0426-SM-3NM91	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909117
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1827
hormone-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-Epithelial_F1-pEpi11_FU1_shared_B_ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
autoimmune disease of gastrointestinal tract	GWASdb SNP-Disease Associations	1.0	0.601018
Cecum cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59032
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Basolateral cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8486
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96008
BRD-K34677894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30044
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40995
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44647
BRD-K32362211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36732
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04808
GPR120_KO_GDS4830_413_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lymph node cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.817046
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28592
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041547
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
positive regulation of protein transport	GO Biological Process Annotations 2015	1.0	null
KMS27	DepMap CRISPR Gene Dependency	1.0	2.40105
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88779
BRD-K04771555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00796
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05953
BRD-K96144282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00696
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
KMBC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80471
ERBB2_druginhibition_8_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.40782
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883072
cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.346829
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72537
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911168
response to acid chemical	GO Biological Process Annotations 2015	1.0	null
BRD-K21732483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43729
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.883476
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9107
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.8405
SHP-77	GDSC Cell Line Gene Expression Profiles	1.0	2.67895
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.51965
BRD-K59006776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68105
Perturb_11405_KD_RB1_SRP099582	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33581
amacr	GeneRIF Biological Term Annotations	1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50511
abnormality of the integument	GWASdb SNP-Phenotype Associations	1.0	0.10481
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23826
NCIH1944	CCLE Cell Line Gene Expression Profiles	1.0	1.49384
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to lipid	GO Biological Process Annotations 2015	1.0	null
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.225826
BRD-K47947160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26679
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845405
cellular response to oxygen-containing compound	GO Biological Process Annotations 2023	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
Axillary bud meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836808
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962732
BRD-K52441396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21365
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43045
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4494
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-96	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35898
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952812
all	GWASdb SNP-Phenotype Associations	1.0	0.08672
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.03892
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9857	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.70136
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E6-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4832
hemolytic anemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.602429
male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.1009
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1807
JAK2_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
PMC4416014-pone.0125585.s010.xls-d_-BNC_network-Interactor_B_BNC1	Rummagene Transcription Factor Associations 2026	1.0	null
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.774834
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
dbtrg05mg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.65511
BRD-K52713598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18964
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5866
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053273
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53469
D-423MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56829
thalassemia	GWASdb SNP-Disease Associations	1.0	1.49392
parasitic infectious disease	GWASdb SNP-Disease Associations	1.0	1.00221
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
hsa-miR-575	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945894
neoplasia	GeneRIF Biological Term Annotations	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.47
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8256-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16314
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7432
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4957
BRD-K50700697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39637
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0138
BRD-K79299080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06939
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8987
NCI-H226Br cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	2.13764
GTEX-X88G-0426-SM-47JZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1801
GTEX-XUJ4-2826-SM-4BOQ2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850796
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.974864
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01606
hsa-miR-1278	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_9533_KO_CEP83_SRP379861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.50257
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.986776
BRD-K97732674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51751
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.69362
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24631
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K49040541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21115
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09345
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291365
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	0.126346
prostate gland intraepithelial neoplasia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.59721
tissues	GeneRIF Biological Term Annotations	1.0	null
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17199
BRD-K97393725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18979
KMRC20	DepMap CRISPR Gene Dependency	1.0	2.15071
Scent gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
BRD-K18709210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2378
promoters	GeneRIF Biological Term Annotations	1.0	null
BRD-K84663394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05359
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myc-CaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
BRD-K67813189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01926
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.49316
positive regulation of transport	GO Biological Process Annotations 2015	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21122
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-297	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K42081955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56454
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
CRCGN014_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22725
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919762
BRD-K34720817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06834
BRD-K41307363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00161
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16731
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.924796
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3022
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3662
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6444
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9317
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4102
LK2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48795
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3334
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14734
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNB75	BioGPS Cell Line Gene Expression Profiles	1.0	1.57702
BRD-K35860167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90353
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.64292
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NCIH1155	DepMap CRISPR Gene Dependency	1.0	2.02235
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K31783246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11075
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hfl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
LN18	CCLE Cell Line Gene Expression Profiles	-1.0	-2.50308
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36697
parasitic protozoa infectious disease	GWASdb SNP-Disease Associations	1.0	1.00221
Perturb_9004_KD_C19orf12_SRP212737	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
BRD-K61711624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10707
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3881
melanocyte proliferation	GO Biological Process Annotations 2023	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62574
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.120293
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885628
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37709
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3258
Olfactory transduction	KEGG Pathways 2026	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHH	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
Benign Prostatic Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.313
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30557
BRD-K47049026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69786
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate gland stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36595
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.64303
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-542-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-UPJH-0726-SM-4IHJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15727
BRD-K63778487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.067
Iris sphincter muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
BRD-K35935439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18895
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	1.0	1.48072
PANC1005	DepMap CRISPR Gene Dependency	1.0	4.7005
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71138333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43286
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43515
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5863
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4734-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-T1-A6J8-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL12RB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471185
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43549
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30868
17177833-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K36164005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10018
BRD-K25822126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82398
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
positive regulation of cAMP-mediated signaling	GO Biological Process Annotations 2023	1.0	null
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07441
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01039
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43304
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48645
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18107
BRD-K05586628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08077
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.29385
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46658
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1992
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28776
regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27308
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	2.04707
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
overexpressed	GeneRIF Biological Term Annotations	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.82746
hsa-miR-410	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1877
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gproteincoupled	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09559
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K77345736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41283
ME-180	GDSC Cell Line Gene Expression Profiles	1.0	1.4734
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70895130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12074
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55998
BRD-K56373119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17758
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.85917
cellular_component	GO Cellular Component Annotations 2015	1.0	null
abnormality of temperature regulation	GWASdb SNP-Phenotype Associations	1.0	0.881393
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Brain_CT2_Exc L3-5 FEZF2 ASGR2	HuBMAP ASCT+B Annotations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393819
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11428
hsa-miR-514	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67406
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
pt3	GeneRIF Biological Term Annotations	1.0	null
GSE160293_2_v_4_celf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2433
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911168
BRD-K72795491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43901
CRCGN011_HEPG2_24H:E09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.068
BRD-K04192407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28345
BRD-K03673270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20578
psa	GeneRIF Biological Term Annotations	1.0	null
Prostate gland epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.95
lncap cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.950823
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54541
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10517
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34396
A-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
FTC-133	GDSC Cell Line Gene Expression Profiles	-1.0	-2.54264
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.94511
BRD-K73874262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3333
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
abnormal carotid body physiology	MGI Mouse Phenotype Associations 2023	1.0	null
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.960797