association	dataset	threshold value	standardized value
AKR1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00225
BXPC3	DepMap CRISPR Gene Dependency	1.0	2.57446
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89102
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62321
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.37618
Beta thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60826
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2172
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8291
Perturb_9927_KD_SRSF5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.96327
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6549
GPATCH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32921
RUNX1_01_47	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.00444
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17838
GTF2B	ENCODE Transcription Factor Targets	1.0	null
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38577
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3039
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
STAT5A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74249
Signal Transduction	Reactome Pathways 2014	1.0	null
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52059
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87004
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4001
Erythroid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
NCI-H226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63979
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
HES3_KD_GSE64449_187_mouse_Min6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5236
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33987
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96197
POU5F1-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30186
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55918
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23149
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06477
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43729
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1058
Perturb_10165_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.79656
496100560_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.14805
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03549
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WO-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.611229
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.049
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66414
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19595
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.77529
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.47007
NR3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65213
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904796
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02553
Brain Lower Grade Glioma_LGG_TCGA-HT-7681-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6385
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895178
ERRFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33874
CBX3	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.24913
ZNF274	ENCODE Transcription Factor Targets	1.0	null
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50904
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.778
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4451
496100297_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17572
AU565	DepMap CRISPR Gene Dependency	1.0	2.93459
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79321
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67776
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7355
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9895
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.087
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48826
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3461-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBXW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59547
PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32591
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4776
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84661
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1865
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33436
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25334
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4549
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58456
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9641
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.519
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847224
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82719
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72867
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55992
SH10TC	DepMap CRISPR Gene Dependency	1.0	4.29689
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50547
PMC10952034-mmc2.xlsx-Table_S1-Table_S1_Pooled_shRNA_screen_analysis_to_identify_genes_selectively_required_for_the_proliferation_of_MYC_overexpressing_cells_Related_to_Figure_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
pou4f1_20376082_fetal_liver_lof_mouse_gpl1261_gds4042	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.23677
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93483
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.501
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68669
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.39094
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5127
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
Brain Lower Grade Glioma_LGG_TCGA-HT-7478-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91839
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04762
MYC_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55599
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0142
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98101
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87308
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04066
Perturb_9943_KD_PUS1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.5229
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50116
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.64245
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10172_KO_TOX4_SRP300474	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.4951
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53019
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14952
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.644
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28692
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.575
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	77.7189
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56206
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.37918
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
Brain Lower Grade Glioma_LGG_TCGA-DU-8167-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54697
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
UBTFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22889
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18285
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Perturb_10006_KD_SF3B1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.37463
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55486
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50218
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.5194
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95837
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
RAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58959
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37369
signal transduction	GO Biological Process Annotations 2015	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4524
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92001
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70035
MND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63819
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40465
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36834
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78105
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06908
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904898
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89617
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20012
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73595
IRF1	ENCODE Transcription Factor Targets	1.0	null
ACAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21129
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5055
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25074
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63321
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4796
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24642
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98974
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.115
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5311
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.11492
NCIN87	DepMap CRISPR Gene Dependency	1.0	3.64692
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07012
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03549
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94864
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07546
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
IPC298	DepMap CRISPR Gene Dependency	1.0	2.13198
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24222
GTF3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42295
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40986
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48326
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65355
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.949599
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8421
TC138	DepMap CRISPR Gene Dependency	1.0	2.64221
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85016
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48916
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
GABRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99516
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10901
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882558
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10865
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38685
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.5035
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911393
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91349
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903937
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870598
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86023
biological regulation	GO Biological Process Annotations 2015	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6506
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0564
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01057
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53968
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54891
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8107
LPS141	DepMap CRISPR Gene Dependency	1.0	2.0153
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4327
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.9178
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5768
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41957
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESS1	DepMap CRISPR Gene Dependency	1.0	2.38329
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.827
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89795
Perturb_9941_KD_MBNL1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.858
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94831
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80532
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29716
Perturb_3586_KD_KHSRP_SRP250831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.1891
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3583
Perturb_9934_KD_AKAP8L_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.0257
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88493
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
MEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81546
ZNF143	ENCODE Transcription Factor Targets	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29716
RHOQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70372
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.34135
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0381
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85153
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924214
Brain Lower Grade Glioma_LGG_TCGA-FG-8182-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57084
GP5D	DepMap CRISPR Gene Dependency	1.0	3.0131
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.368
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8585
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0433
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9128
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05274
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.86
UWB1289	DepMap CRISPR Gene Dependency	1.0	2.6906
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
SPI1	ChEA Transcription Factor Targets	1.0	null
Perturb_9945_KD_UTP18_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.80454
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.954
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56124
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1436
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4377
thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.992752
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.841742
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
HT-1376	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15502
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45006
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0433
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.4848
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
ZNF274_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7244
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.68312
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970586
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10443
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
Perturb_9984_KD_TBRG4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.97841
EN	DepMap CRISPR Gene Dependency	1.0	3.37825
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31379
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4567
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87516
Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9852_KD_LUC7L_ERP124746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.41611
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4699
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6743
COMMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5866
ERG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23452
TIA1_KO_GSE54418_261_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4349
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.1077
CARD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49425
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33735
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.9522
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS	DepMap CRISPR Gene Dependency	1.0	2.21432
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37288
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95217
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85106
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3704
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9955_KD_SF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.4084
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55984
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82507
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0248
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6944
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15793
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4794
HT55	DepMap CRISPR Gene Dependency	1.0	2.48942
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40729
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829852
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.899413
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86489
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9909_KD_RBM17_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.1264
GABPA	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31681
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85873
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10379
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.5262
RESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38224
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
Perturb_10015_KD_HNRNPC_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.2943
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26849
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75242
Perturb_9931_KD_TRA2A_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.11869
CCDC78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62649
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.72169
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8825
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863633
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
CEBPB	ChEA Transcription Factor Targets	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90888
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07526
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63827
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4044
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1316
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83396
Perturb_10000_KD_CPSF6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.68141
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.37505
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	5.55364
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.52688
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99011
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNDZ	DepMap CRISPR Gene Dependency	1.0	2.4434
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984312
Perturb_9942_KD_NAA15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.33302
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829852
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02189
RCOR1	ChEA Transcription Factor Targets	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12562
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95901
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75089
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38045
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982595
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37369
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3271
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4292
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1754
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7778
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24113
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.51415
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.782
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43686
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07527
496100427_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01123
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37191
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15793
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62872
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26365
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6939
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.8958
ZNF888	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
C8orf33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53003
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982595
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59567
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02996
Perturb_10029_KD_CELF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.62309
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5368
Perturb_10030_KD_EIF4G2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.7696
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5887
ERBB3_drugactivation_70_GSE21463	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.592738
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95702
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10093
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9867_Mut|KD_SRSF2_SRP368113	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26788
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38653
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20985
OE33	DepMap CRISPR Gene Dependency	1.0	2.18753
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1941
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
DIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0015
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-800	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6697
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8717
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86942
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04275
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02784
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87227
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.30223
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863633
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24528
MAX_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9930_KD_TIA1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.5387
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21334
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79498
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
SIRT6	ENCODE Transcription Factor Targets	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5004
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91678
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48327
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07376
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885604
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
GSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20658
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89266
WHSC1	ENCODE Transcription Factor Targets	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.478668
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07547
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02784
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5296
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74418
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48556
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100585_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45514
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
beta thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.20229
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSN1	DepMap CRISPR Gene Dependency	1.0	2.42726
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22685
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55205
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14838
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.16
EIF5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82193
FUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83719
Malaria	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76708
Perturb_9935_KD_ATP5F1C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.17763
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3891
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04074
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32178
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02011
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2397
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53997
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4769
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31055
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1255
IGR39	DepMap CRISPR Gene Dependency	1.0	3.61198
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8874
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5628
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86258
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938673
HIF1A_01_348	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59652
496100588_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01631
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44585
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05349
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12835
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48882
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48172
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09156
GPR63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92711
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1281
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5135
METRNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35595
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87476
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973983
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6784
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63868
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15793
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31052
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04218
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1556
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31147
biological_process	GO Biological Process Annotations 2015	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0021
PMC10290283-biol-2022-0622-sm3.pdf-389-ZNF114_ZNF114	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3681
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4171
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.70317
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828852
LUDLU1	DepMap CRISPR Gene Dependency	1.0	2.01811
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7864
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58352
Perturb_10004_KD_KRR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.79796
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17048
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47949
496100498_PCx_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25228
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71788
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92851
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1227
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80907
RBM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC27A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9905_KD_SSB_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.54825
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.3477
CAKI1	DepMap CRISPR Gene Dependency	1.0	3.94543
Delta beta-thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3038
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94398
GHDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8236
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5163
GSE140997_10_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982595
CAL33	DepMap CRISPR Gene Dependency	1.0	3.51479
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77262
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64489
NCI-H716	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5634
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
CCZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74446
GRIPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53713
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2948-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RC-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7068
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75636
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76499
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08172
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965926
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50411
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09925
Brain Lower Grade Glioma_LGG_TCGA-HT-7480-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85879
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3608
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.38858
STAT5A	ENCODE Transcription Factor Targets	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01571
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19063
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08879
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941549
sensory perception	GO Biological Process Annotations 2015	1.0	null
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21161
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.281
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.71426
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.5376
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83095
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973983
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15984
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2322
POU5F1	ChEA Transcription Factor Targets	1.0	null
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7774
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25959
anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.264431
membrane part	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33188
MAZ	ENCODE Transcription Factor Targets	1.0	null
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70333
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1726
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.928
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.9659
COL9A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44012
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884201
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9717
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14913
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.35435
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1865
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52066
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912508
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8507
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7775
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9483
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.1726
FAM221A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7878
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2135
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33004
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
RVH421	DepMap CRISPR Gene Dependency	1.0	2.3587
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830956
Brain Lower Grade Glioma_LGG_TCGA-HT-7605-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65504
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1445
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39924
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90393
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09221
Perturb_17406_KD_EIF2AK1_SRP261169	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.57408
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.526
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90191
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2685
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81369
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99433
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27202
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LASP1NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80581
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10718
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33537
Perturb_9964_KD_NSUN2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.09942
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27284
Canavan disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0783
ATF1	ENCODE Transcription Factor Targets	1.0	null
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73732
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0827
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56299
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6995
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0003
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
MAX	ENCODE Transcription Factor Targets	1.0	null
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08953
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65522
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26179
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6015
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89043
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6787
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27662
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53963
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57952
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13373
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12997
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98126
Perturb_10154_KD_ZRSR2_SRP265290	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.53333
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46402
Perturb_9910_KD_CIRBP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.57831
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85697
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40371
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14468
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05381
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83335
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0436
NR2F2	ENCODE Transcription Factor Targets	1.0	null
7TM GPCR, olfactory receptor/chemoreceptor Srsx	InterPro Predicted Protein Domain Annotations	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9699
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965926
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NYNRIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31919
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71178
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0128
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92923
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27865
FAM83H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58091
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45793
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30391
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9662
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47364
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24642
CCNT2	ENCODE Transcription Factor Targets	1.0	null
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_8_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17944
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26183
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97153
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26818
Perturb_9967_KD_SRPK2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.54016
single-organism process	GO Biological Process Annotations 2015	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20667
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2428
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63039
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00861
SAP30	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8278
KDM1A	ENCODE Transcription Factor Targets	1.0	null
Perturb_10099_KD_HNRNPU_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.98857
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5976
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42107
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
PCBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22196
Perturb_9919_KD_MATR3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.63723
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7349
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.827
SKNFI	DepMap CRISPR Gene Dependency	1.0	3.23385
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35372
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941549
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22244
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17835
TEAD4	ENCODE Transcription Factor Targets	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830455
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040144
MM1S	DepMap CRISPR Gene Dependency	1.0	2.04602
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49098
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32457
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1501
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38804
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6955
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03187
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68454
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1516
E2F6	ENCODE Transcription Factor Targets	1.0	null
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31487
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00893
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6524
MMAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11186
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.863474
KU812	DepMap CRISPR Gene Dependency	1.0	4.39588
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80031
Olfactory transduction	KEGG Pathways 2026	1.0	null
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.975656
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25735
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87546
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79193
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7738
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51266
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82467
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49264
L1CAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76891
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39447
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91616
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.525971
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85765
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24042
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6301
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4752
GATD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04696
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18667
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6162
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912508
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6753
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6022
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.506155
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6689-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.803
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.39578
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91938
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.419142
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27733
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77996
Erythroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37369
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58877
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8430-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
496100476_TCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08474
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66361
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2368
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973983
Perturb_9944_KD_RBM15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.767
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67023
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86119
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36761
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.90325
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8419
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65961
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32875
RAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12917
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1446
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
L33	DepMap CRISPR Gene Dependency	1.0	9.46859
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38419
KDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75817
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30705
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
Vaginal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
ATAD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45112
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984312
A253	DepMap CRISPR Gene Dependency	1.0	2.75401
Perturb_17404_KD_EIF2AK1_SRP261169	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.42518
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26996
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.3704
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.0629
Bone_Marrow-erythrocyte	Tabula Sapiens Gene-Cell Associations	1.0	1.1547
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33027
ALDH16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82215
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21489
Parasitic protozoa infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25098
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4138
ATXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94863
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	97.56
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04158
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5829
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37287
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.13018
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75712
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965926
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4332
SBK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78336
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06204
DLD1	CCLE Cell Line Gene CNV Profiles	1.0	1.46516
Sarcoma_SARC_TCGA-X6-A7WA-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9983
PEG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40482
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841474
OPLAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65888
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41042
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35478
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28901
Perturb_9903_KD_SLTM_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.53408
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5839
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95565
Brain Lower Grade Glioma_LGG_TCGA-DU-7300-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MELK_knockdown_150_GSE32873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.34856
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80843
NB1643	DepMap CRISPR Gene Dependency	1.0	2.87532
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5016
CHD1	ENCODE Transcription Factor Targets	1.0	null
Perturb_10096_KD_AGO3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43125
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
LOUCY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30301
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040986
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27661
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61137
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.05159
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67954
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
HDAC1	ENCODE Transcription Factor Targets	1.0	null
HOXC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1613
EP300	ENCODE Transcription Factor Targets	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14838
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.66656
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14838
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
POMC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35844
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98876
JHOS2	DepMap CRISPR Gene Dependency	1.0	5.06023
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96197
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.975856
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20619
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72158
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67255
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60296
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044023
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4165
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5968
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039156
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35749
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09063
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1239
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
MAP3K7_knockout_246_GSE34417	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.33702
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832948
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.465416
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3014
UBTF	ENCODE Transcription Factor Targets	1.0	null
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4286
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46464
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.66886
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2584
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5201
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26647
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95708
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9946_KD_SAFB2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.69408
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26855
JJN3	DepMap CRISPR Gene Dependency	1.0	2.53923
Perturb_9939_KD_KIF1C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.92719
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85668
Prostate adenocarcinoma_PRAD_TCGA-J4-A83K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IH-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6516
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17518
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52449
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4737
CRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12061
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
Perturb_9969_KD_WDR3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.72272
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867449
MYC_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33999
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5358
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57806
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0487
RASAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4037
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.850257
PPP1R14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55784
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A60K-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10080_KD_IGF2BP3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.5145
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.05159
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7772
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.7148
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.1001
HS936T	DepMap CRISPR Gene Dependency	1.0	6.52302
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990677
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5104-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86564
DEPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59472
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0397
Brain Lower Grade Glioma_LGG_TCGA-P5-A77X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25335
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984312
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42147
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.06756
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.471
SK-N-AS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42808
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43215
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.6867
membrane	GO Cellular Component Annotations 2015	1.0	null
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23105
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.5029
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74122
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78769
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33987
POU3F2	ChEA Transcription Factor Targets	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PAXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18825
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1333
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95931
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9892
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93107
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38274
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02479
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8108
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
TSSK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03578
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6483
Signaling by GPCR	Reactome Pathways 2014	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
PML	ENCODE Transcription Factor Targets	1.0	null
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97003
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47673
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45347
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2213
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4385
496100331_TCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.33197
NFKBIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80646
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03151
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28371
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55773
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42689
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2R5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16911
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCARB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99134
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913031
VPS4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39018
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932766
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936973
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
Sensory Perception	Reactome Pathways 2024	1.0	null
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20961
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02541
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.228
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6384
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1509
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36269
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840365
ZNF573	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02291
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.90298
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
Perturb_9900_KD_FASTKD2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.1173
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64012
MIDEAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33774
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53446
MAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90675
SLC31A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70004
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76121
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47005
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23119
Perturb_10007_KD_HNRNPA1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.04696
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94505
HTATSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08915
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9806
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.796
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965926
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41183
NNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48938
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38537
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3753
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.52896
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49463
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97023
Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22237
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99897
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74943
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48129
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13383
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903535
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9649
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4192
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899529
YAMATO	DepMap CRISPR Gene Dependency	1.0	2.82131
neurological system process	GO Biological Process Annotations 2015	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5707
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.897359
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9071
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11931
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
EID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82615
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56587
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17395
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64889
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50127
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.51456
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03132
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2806
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.6
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.5712
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
ARF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56127
RBM48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34538
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.580374
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02784
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28233
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29941
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91298
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94225
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941549
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45933
Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05036
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88304
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60364
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64166
MAFF	ENCODE Transcription Factor Targets	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4639
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9558
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37462
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00588
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903535
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934168
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.827724
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10097_KD_CNOT8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.1636
BICR78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0161
Perturb_9992_KD_PABPC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.39141
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76293
Prostate adenocarcinoma_PRAD_TCGA-J4-A83L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100526_TCx_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71607
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22077
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07359
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28801
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.66771
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61099
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9328
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52999
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91158
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44206
CTCF	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57155
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.5226
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11234
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78378
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73198
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26579
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1769
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95318
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4056
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9026
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.25377
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75577
SUM52PE	DepMap CRISPR Gene Dependency	1.0	3.74566
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.73027
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3259
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3785
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9940_KD_MAK16_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.69835
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3056
PRPF38A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90368
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
MAFK	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3919509-NIHMS471461-supplement-3.xls-Table_S1-ZNF33A_ZNF33A	Rummagene Transcription Factor Associations 2026	1.0	null
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43586
ERCC6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68397
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.81745
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79447
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06892
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
GATA2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23464
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2428
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
RFX5	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.21619
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96779
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40558
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20678
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6665
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40553
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.346
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32593
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3829
Perturb_9921_KD_PCBP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.45289
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
YY1	ENCODE Transcription Factor Targets	1.0	null
JOSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17368
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91359
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93637
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41594
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
MXI1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72906
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59776
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6954
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4805
LAPTM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57302
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16568
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09638
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
MTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52638
RC3H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55941
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.978611
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1028
YBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67625
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863633
STAT3	ENCODE Transcription Factor Targets	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8207
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6498
CEBPD	ENCODE Transcription Factor Targets	1.0	null
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8261
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
Perturb_9932_KD_AGGF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.70959
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.0753
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8688
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904898
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5854
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29146
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23057
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79379
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44809
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4878
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.70552
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02719
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82069
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07376
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41639
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912508
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
Perturb_9938_KD_DKC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.50175
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
TTPAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61453
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46555
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
Perturb_9913_KD_HNRNPK_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.69077
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76162
KLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04204
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8971
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82798
ARID3A	ENCODE Transcription Factor Targets	1.0	null
TMEM89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94709
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04582
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37116
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8558
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939214
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912508
GID8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74686
Brain Lower Grade Glioma_LGG_TCGA-HT-8111-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96818
ENTPD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72628
DMRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33114
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02338
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929123
CHD2	ENCODE Transcription Factor Targets	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6127
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13918
Perturb_9933_KD_AKAP8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.72444
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36066
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04275
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27662
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09458
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3807
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.57371
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965926
Alpha thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45222
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4586
receptor activity	GO Molecular Function Annotations 2015	1.0	null
496100310_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26849
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72397
DMRTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58626
POU5F1-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32509
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8066
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10901
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59438
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.3258
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23744
tn5b14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
RBBP5	ENCODE Transcription Factor Targets	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.824063
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
HGC27	DepMap CRISPR Gene Dependency	1.0	3.61146
Perturb_8773_KO_ZNF410_SRP273250	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.66385
Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11056
GSK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40894
Perturb_10095_KD_AGO2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.4641
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55611
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75721
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
cellular_component	GO Cellular Component Annotations 2015	1.0	null
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49963
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80291
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33349
SFXN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78337
Parasitic infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.748
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.38632
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912508
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8ZZ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9482
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF836	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52868
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2667
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43654
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1717
NFYA_01_288	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58755
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51246
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05462
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09329
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93218
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05349
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65059
NANOG	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.49
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
CALM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98828
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52545
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
PTDSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85252
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96197
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00087
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
NSDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02573
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.699
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6493
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55384
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66848
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.563
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63437
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82962
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79217
SPATA33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65692
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0584
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45626
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17686
TRIM28	ENCODE Transcription Factor Targets	1.0	null
PRKAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13192
CDH24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86187
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.1167
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01714
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6164
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28221
CAMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57927
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31277
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32188
FGF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09394
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6897-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82599
Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.34711
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.64489
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.7613
Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63624
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840365
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11126
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0917
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18723
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.984747
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9315
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1834
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12788
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89328
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48855
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50642
C4orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63872
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47101
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17128
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18713
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43278
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
MES-SA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6955
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02015
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00261
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66878
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27614
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65913
CNOT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.585
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00016
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.18672
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830455
SKGII	DepMap CRISPR Gene Dependency	1.0	2.88419
LZTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9996
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6165
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82258
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16374
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.8769
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57055
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84002
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8499
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6348
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9704
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40401
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904898
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55311
FASLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
CHK1_KD_GSE54268_666_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89684
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4622
ETV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25027
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13293
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78441
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.34613
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94004
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82032
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
MYLA	DepMap CRISPR Gene Dependency	1.0	2.47183
RAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32182
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6806
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.27819
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94657
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55393
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
EZH2	ENCODE Transcription Factor Targets	1.0	null
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.795
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28682
HFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70783
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.577
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64538
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04275
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04189
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9909
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68926
RBMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59716
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67736
LBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60583
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9561
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3076
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3446
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09974
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14397
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90697
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7175
SOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
TSEN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29179
PE/CA-PJ15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUIT2	DepMap CRISPR Gene Dependency	1.0	6.23208
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17143
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93909
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.796566
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6669
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0834
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5925
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.7408
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
EBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71149
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53706
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.766
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6197
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30643
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
NCI-H209	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3084
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2762
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62591
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84353
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LI7	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30471
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11138
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911393
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21568
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
TAL1	ENCODE Transcription Factor Targets	1.0	null
BICDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40513
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
k562clones	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09207
WM115	DepMap CRISPR Gene Dependency	1.0	2.469
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73248
HDAC2	ENCODE Transcription Factor Targets	1.0	null
496100287_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13427
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85074
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15006
Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78572
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05462
Metallochaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91169
ZNF764	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26413
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF768	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74425
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66574
B9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27574
CUX1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null