association	dataset	threshold value	standardized value
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.2776
immune system disease	GWASdb SNP-Disease Associations	1.0	0.057186
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5746-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tn5b14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6365
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5921
RBPJ	ChEA Transcription Factor Targets	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
RHOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91677
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30239
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00663
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08929
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.799083
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
leukopenia	GWASdb SNP-Disease Associations	1.0	0.389876
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12734
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
FADU	DepMap CRISPR Gene Dependency	1.0	2.13985
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.741
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06839
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26472
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6707
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909367
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26628
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5475
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.03979
Lung adenocarcinoma_LUAD_TCGA-MP-A4TF-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55876
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.36717
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9904
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99969
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.614295
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.56635
LAMTOR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76553
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72929
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88012
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.988003
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65296
Heterotrimeric G-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9827
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.60516
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
NZM3	DepMap CRISPR Gene Dependency	1.0	2.13732
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64712
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0409
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09845
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06387
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
21NT	DepMap CRISPR Gene Dependency	1.0	2.60495
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20115
Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9962
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23537
EP300	ENCODE Transcription Factor Targets	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5272
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.38875
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.963236
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.851902
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93614
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07076
Intracranial aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09092
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
abnormal leukocyte count	GWASdb SNP-Phenotype Associations	1.0	0.389633
ZNF471	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49761
MOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66678
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.979
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80943
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830513
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28511
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49495
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90482
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35916
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54914
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13264
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.3232
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2234
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860877
ZNF100_01_124	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.10504
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D425	DepMap CRISPR Gene Dependency	1.0	4.8736
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16679
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59523
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38827
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.1422
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40136
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894868
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.7496
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84523
PBX1	ChEA Transcription Factor Targets	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21844
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1402
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100314_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45712
leukopenia	GWASdb SNP-Phenotype Associations	1.0	0.704969
membrane	GO Cellular Component Annotations 2015	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.82677
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48703
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853588
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913147
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5748
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14372
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67776
SLC39A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34239
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6177
Discoidal high-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6909
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9829
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0927
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.3867
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3368
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24321
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44649
Liver hepatocellular carcinoma_LIHC_TCGA-PD-A5DF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.41554
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MDAMB436	DepMap CRISPR Gene Dependency	1.0	2.11293
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79092
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882718
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal neutrophil cell number	GWASdb SNP-Phenotype Associations	1.0	0.704969
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51211
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3765
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853588
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9302
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.28043
Myocardial infarction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8334
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and neck cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885809
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12721
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08929
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34122
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66409
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAN2	DepMap CRISPR Gene Dependency	1.0	3.73515
PIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75997
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.114156
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67604
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00663
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20108
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26821
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33857
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894868
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0522
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89491
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.60091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
LUDLU1	DepMap CRISPR Gene Dependency	1.0	3.39572
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860877
TE1	DepMap CRISPR Gene Dependency	1.0	3.20398
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07154
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7058
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990788
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9003
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40572
SIRT3_KO_GDS4817_417_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of neutrophils	GWASdb SNP-Phenotype Associations	1.0	0.389633
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68926
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.024766
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.54835
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9496
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.35
LANCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17634
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
FLAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56376
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.7729
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17821
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1837
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70078
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20042
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21028
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974294
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23462
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.52537
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43855
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3333
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54858
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2873957-pone.0010709.s003.xls-OCT4-only_OCT4_motif_present_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-487-CENPA_CENPA	Rummagene Transcription Factor Associations 2026	1.0	null
ZIC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12611
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943757
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2157
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64428
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02103
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943757
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_5_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.02763
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7738
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01577
MRPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55379
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.84598
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.943
Cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0843
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
SKNFI	DepMap CRISPR Gene Dependency	1.0	10.0374
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GFER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47354
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09882
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914723
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.31238
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81989
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885809
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00009
GDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86365
YD38	DepMap CRISPR Gene Dependency	1.0	10.5016
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61697
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.61553
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989751
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A4SS-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
cell part	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50019
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5037
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP7D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88292
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859846
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37578
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.995
Intracerebral hemorrhage	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9368
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.79
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17678
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05832
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7623
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943757
REST_01_337	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59179
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
Myocardial infarction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
Extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06835
Myxopapillary ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88084
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40074
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6155
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21183
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HUCCT1	DepMap CRISPR Gene Dependency	1.0	4.18213
EW-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84846
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42642
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5203
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52183
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.33023
GAS2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91852
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989751
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02518
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2741
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62833
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3957
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.49528
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.191
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.09086
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84835
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2846
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5565
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82994
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08929
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4828-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HO1U1	DepMap CRISPR Gene Dependency	1.0	3.41924
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36344
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828366
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30865
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83792
ODC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34512
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.904947
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19592
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47571
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.1701
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04719
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
DUS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52379
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH747	DepMap CRISPR Gene Dependency	1.0	2.67357
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coronary artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943757
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79202
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0241
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43654
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48391
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925574
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8713
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67462
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5834
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.32418
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
ACSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5794
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59466
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1308
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9807
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
AP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82695
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.999886
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48622
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79204
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49158
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2325
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4640-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2349
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4804
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4513
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76299
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.777579
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
PCSK9-LDLR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
Spinal cord ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46976
QPCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46157
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.3232
KASUMI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97521
ST486	DepMap CRISPR Gene Dependency	1.0	2.75782
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6094
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91405
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02003
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5389
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24686
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC56	DepMap CRISPR Gene Dependency	1.0	2.83219
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27205
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
Lung adenocarcinoma_LUAD_TCGA-62-A470-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21165
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96081
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81222
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86993
Premonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94864
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
CD164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9396
SLC45A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70849
NCIH2030	DepMap CRISPR Gene Dependency	1.0	3.18768
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1329
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71508
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96371
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02003
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3606
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13735
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37358
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
Functioning pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5961
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82477
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1167
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93431
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830513
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-1.1422
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06923
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.35068
MOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44572
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56533
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.58568
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.207066
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62199
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16626
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60958
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943757
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33857
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.997
496100454_FWM_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.60458
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75641
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61049
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23512
Homomeric SMAD protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85294
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62112
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27823
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71662
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BPHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27657
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29967
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25212
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87785
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1514
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61771
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7004
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90804
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6497
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33922
KASUMI1	CCLE Cell Line Gene CNV Profiles	1.0	1.4089
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2401
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89405
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.185393
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7103
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885809
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57892
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98488
RHOQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69551
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00812
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.33954
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39836
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25212
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1701
Moyamoya disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.79899
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980852
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91165
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47092
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81148
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51071
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.41395
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943757
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.68287
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860877
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
EZH2	ENCODE Transcription Factor Targets	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5643
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98021
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09845
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22713
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54516
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07928
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.357
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85829
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59579
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16578
MAP6D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2222
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9802
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0998
membrane part	GO Cellular Component Annotations 2015	1.0	null
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.55411
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828874
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1901
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55622
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5568
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1979
PLIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57754
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07928
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96336
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3037
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74371
agranulocytosis	GWASdb SNP-Disease Associations	1.0	0.809109
Lung adenocarcinoma_LUAD_TCGA-78-7150-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77618
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.40757
NR1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78131
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50603
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7433
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6968
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99997
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934888
EAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14492
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46211
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.943188
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876889
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.38059
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	1.66319
SNU81	CCLE Cell Line Gene CNV Profiles	1.0	1.68317
U031	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6950-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75209
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17871
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74537
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48391
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.691729
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7748-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52946
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860877
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.52562
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6793
POLR2A	ENCODE Transcription Factor Targets	1.0	null
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96601
SLC43A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03362
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5578
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1514
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91305
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03562
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.39935
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.91625
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95289
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33436
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.493
SNU16	DepMap CRISPR Gene Dependency	1.0	2.5044
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2681
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1774
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0536
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6119
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A72E-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4424-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03471
abnormality of granulocytes	GWASdb SNP-Phenotype Associations	1.0	0.307634
Perturb_15517_KD_E2F2_SRP314859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.44215
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51647
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.89056
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9669
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943757
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7442
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78681
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852974
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0773
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0528
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17678
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36988
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46021
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75869
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44649
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80094
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.40685
Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71965
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04365
Lung adenocarcinoma_LUAD_TCGA-67-6217-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51428
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.84669
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17401
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54976
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATU8902	DepMap CRISPR Gene Dependency	1.0	6.55331
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42399
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00098
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59767
CCT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42327
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1164
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991796
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76071
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.094124
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894868
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.3145
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9073
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIMKLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70275
C8166	DepMap CRISPR Gene Dependency	1.0	4.05449
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32327
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01087
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.85146
SLC25A22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72227
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970492
neutropenia	GWASdb SNP-Disease Associations	1.0	0.809109
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14768
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976245
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4272
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.548358
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01671
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87153
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
FAM110A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85716
INA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81016
Prostate adenocarcinoma_PRAD_TCGA-HC-7820-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4314
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860877
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	2.8126
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41712
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59579
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.93013
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0086
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24293
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
EDA2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54459
MERO25	DepMap CRISPR Gene Dependency	1.0	2.4118
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04493
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.109048
ICC3	DepMap CRISPR Gene Dependency	1.0	5.34567
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830513
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0406
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32685
CLCN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71111
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26472
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47552
LOVO	DepMap CRISPR Gene Dependency	1.0	2.78014
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74593
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03078
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23465
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42601
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukocyte disease	GWASdb SNP-Disease Associations	1.0	0.339328
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17678
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.68867
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07928
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13801
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8247
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09952
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51664
Olfactory transduction	KEGG Pathways 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982152
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
496100567_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5532
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14676
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KCTD20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83199
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15647
Signaling by GPCR	Reactome Pathways 2014	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13735
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95395
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MPHOSPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00714
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0771
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBXW8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69278
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894868
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859846
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9773
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959608
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9707
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	1.83014
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13688
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13741
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26472
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68321
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837683
SNU423	CCLE Cell Line Gene CNV Profiles	1.0	2.20903
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.854814
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82539
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50396
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27732
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45366
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7972
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4295
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6868
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9194
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21541
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0865
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07154
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925574
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59063
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59579
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95318
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00663
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57213
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46811
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.77909
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05496
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9086
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8876
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913147
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68225
EIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13092
response to stimulus	GO Biological Process Annotations 2015	1.0	null
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05893
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39511
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24645
Cerebral arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.34458
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	3.3796
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07131
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6806
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980107
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3149
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15825
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3951
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01336
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.88081
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04079
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.03098
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.25435
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.613
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0623
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1902
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76299
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.084
GABRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99516
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13444
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07299
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1672
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5623
TRIM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14136
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.941567
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3203
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.09596
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07627
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81116
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07928
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54897
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02528
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50679
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.27327
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6598
DHTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67471
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31735
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19592
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69445
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848939
MOLM13	CCLE Cell Line Gene CNV Profiles	1.0	1.37248
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98264
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5588
neutropenia	GWASdb SNP-Phenotype Associations	1.0	0.704969
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49863
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6968
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Growth hormone secreting pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
P4E6	DepMap CRISPR Gene Dependency	1.0	2.16935
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1246
biological regulation	GO Biological Process Annotations 2015	1.0	null
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.27607
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07154
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62814
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	1.70785
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70334
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33027
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14844
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02003
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
receptor activity	GO Molecular Function Annotations 2015	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.69174
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0048
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5674
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.185393
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02343
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11373_KD_USP22_SRP229365	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.1963
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.30045
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2281
Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.0305
Lung squamous cell carcinoma_LUSC_TCGA-39-5019-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21183
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9893
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6089
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0382
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29967
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3296
OPLAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65888
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92403
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
TMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32482
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23512
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
D-566MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-IK-8125-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.598
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71567
JHH5	DepMap CRISPR Gene Dependency	1.0	2.43032
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
COLO792	DepMap CRISPR Gene Dependency	1.0	6.25967
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02419
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06907
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99428
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99017
all	GWASdb SNP-Phenotype Associations	1.0	0.030932
Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09845
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07248
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2945
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
cellular_component	GO Cellular Component Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1514
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86597
KMS11	DepMap CRISPR Gene Dependency	1.0	2.68241
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	2.70304
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCA1	DepMap CRISPR Gene Dependency	1.0	4.7952
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20345
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05257
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27698
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830513
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4563
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0797
GATA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18698
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1825
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST-SL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13264
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68043
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885809
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68735
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.36535
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Intracranial arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68578
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2788
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SX-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96371
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.927271
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6006
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36481
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8472
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33857
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8CQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905655
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78P-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43175
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69657
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7714
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.3687
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.286
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8632
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
SIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48475
Cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.085
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04422
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83351
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49129
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4518
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6108
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59579
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854253
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1378
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-1.1422
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99742