association	dataset	threshold value	standardized value
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12415
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55799
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58472
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.6029
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89795
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36743
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26691
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.17258
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82667
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04096
Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42986
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17894
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4553
AP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82695
Signal Transduction	Reactome Pathways 2014	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.0
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18973
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3347
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07849
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18616
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24669
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NAGLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24471
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6273
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42859
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15876
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2247
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911461
sirolimus_mus musculus_gpl7202_gse27784	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
ARRDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7842
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50428
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00495
UBTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1852
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55469
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97381
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7986
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23092
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_UCEC_NOT_CESC_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12832
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35895
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3274
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9518
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21048
PNPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02564
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08486
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16023
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19033
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16036
CDH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.755
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
T3M5	DepMap CRISPR Gene Dependency	1.0	2.67695
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.194
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6826
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8306
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07349
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79085
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05168
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911461
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08297
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1818
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32101
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7532
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10501
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.47058
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.6188
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23255
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.2972
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64147
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96959
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832108
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9152
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.963045
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.5566
GSE224576_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.88059
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14001
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94744
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64031
mantle zone of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00639
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.908012
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99052
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89846
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	124.133
ZNF862	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.118
septopallidal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3105
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1726
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.0052
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
TEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0457
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2421
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87054
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96087
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13797
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13916
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60689
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R4-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
SLC25A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67744
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03151
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94542
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41132
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88869
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
MAN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89868
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32488
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19F-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63176
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830846
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862334
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00604
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.39797
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6048
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74507
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66148
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44875
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.943
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67878
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45504
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13066
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20626
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.4155
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35451
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0945
HDMYZ	DepMap CRISPR Gene Dependency	1.0	2.66339
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67931
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1869
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937405
mantle zone of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50736
VPS52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0079
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81793
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85117
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78769
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59047
mantle zone of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37179
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09419
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33191
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89385
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89408
intermediate part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50822
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25995
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8946
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.17258
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884371
mantle zone of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20049
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.0562
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08238
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00059
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01559
H3C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49622
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68564
KIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46488
SH2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28178
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98101
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85307
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09837
r1 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67206
Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59209
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6364
Pons, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.97355
receptor activity	GO Molecular Function Annotations 2015	1.0	null
YOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87353
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2906
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81054
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04321
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
N4BP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89074
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.722
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52943
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02354
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38761
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23572
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5653
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r4 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02983
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50936
ATXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87128
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38778
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5931
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7281
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24994
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63099
LAMA-84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46663
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43462
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73105
FOXK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73934
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26453
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64776
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11926
Primary somatosensory area, unassigned, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15661
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A2PC-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10601
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73784
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51158
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0862
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.0141
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17767
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50837
NDUFS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38609
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00639
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1382
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11775
Scrapie	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7597
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5687
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827686
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62882
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30387
SRY	ChEA Transcription Factor Targets	1.0	null
layer 1 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20734
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9348
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87839
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18079
r7 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05589
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7706
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.880493
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65879
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29257
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05794
CPEB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32933
DLD1	CCLE Cell Line Gene CNV Profiles	1.0	1.33146
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87054
ANAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20518
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28667
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5173
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2568
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09449
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82745
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08658
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825197
HNF3A	MotifMap Predicted Transcription Factor Targets	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43843
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83792
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.62607
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12712
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1429
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.353
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02898
LSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15465
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09811
TSEN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29179
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96201
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.794
HUNS1	DepMap CRISPR Gene Dependency	1.0	2.16118
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25832
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10898
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72461
BRCA1	ENCODE Transcription Factor Targets	1.0	null
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42249
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12543
BAZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7048
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	1.96263
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00977
Ubiquinone biosynthesis complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.494
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37482
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85499
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46782
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05589
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01966
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923762
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44342
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.22332
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1938
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5238
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17944
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74752
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.339
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3963
superficial stratum of FCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00677
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04293
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35357
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.25
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47915
ACSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58383
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.89064
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04293
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62849
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25722
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56096
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9427
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7278
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYLA	DepMap CRISPR Gene Dependency	1.0	2.5516
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RU-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5137
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10028
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36846
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36154
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850719
JUN_01_164	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61574
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6792
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60212
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Signaling by GPCR	Reactome Pathways 2014	1.0	null
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61897
Myocardial infarction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80471
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12386
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9144
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
GDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66694
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29034
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.2841
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67255
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62746
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98532
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61263
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6384
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59059
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF568	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46464
ZNF366	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58351
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44032
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.171
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3879
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989563
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71873
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.176111
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19353
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
DDX60L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01757
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68193
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04999
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
liminal part of the r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24273
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60087
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4063
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950483
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08779
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6764
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.4594
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.765098
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4818
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21423
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93637
sublayer 6a of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39978
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.6475
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37301
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852626
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59339
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95429
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3231
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2683
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10293
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77652
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7046
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60299
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46675
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64741
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30805
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0186
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75218
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43859
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44996
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57594
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08866
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24412
CLOCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90969
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40635
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8257
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12717
SEC16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97598
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
Parabrachial nucleus, lateral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12386
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07057
RCOR1	ChEA Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5629-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06119
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.34585
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6585
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0692
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2402
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2081
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45693
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997113
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11139
RRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13684
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55016
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18861
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71798
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9197
intermediate stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21423
TRMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45181
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32177
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869468
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.698483
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
membrane part	GO Cellular Component Annotations 2015	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36837
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.78752
SORD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51652
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37262
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45432
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46042
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843779
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54642
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948804
ABCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39236
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
intermediate part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37136
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.992
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08161
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.75631
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.15535
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0898
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38397
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858152
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69814
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09342
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12386
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1938
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ALPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41163
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07201
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.49
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6745
GSE160817_7_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47915
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27093
r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45959
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34632
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.50054
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27201
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92851
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49361
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56531
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67975
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24994
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0066
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1293
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.1739
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32099
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80865
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1756
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85458
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40401
Lung squamous cell carcinoma_LUSC_TCGA-60-2715-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7811-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65677
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33514
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23822
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27207
HUH7	DepMap CRISPR Gene Dependency	1.0	9.10367
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8094
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968158
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47465
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.53014
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71408
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72591
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21057
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51E-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0177
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00683
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10237
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6732
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62263
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61641
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5621
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23078
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93835
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0436
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5906
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5093
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.0039
KCNF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59989
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92334
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29271
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91069
CAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89167
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33132
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02165
Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67102
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.75812
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27187
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44625
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90579
VCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15045
CALU6	DepMap CRISPR Gene Dependency	1.0	3.68308
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6947
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09997
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03144
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7697
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82667
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
STARD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29109
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07754
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7781
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68523
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.75642
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04603
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22388
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71501
r3 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65127
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58548
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.06608
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15266
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.3659
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1332
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00495
GIGYF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08218
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87825
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964865
A549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.40448
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.909722
NCIH747	DepMap CRISPR Gene Dependency	1.0	2.11814
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01585
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38645
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03235
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01576
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18752
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87054
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31512
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01081
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51349
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.51027
EPHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40773
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02354
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.7343
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	96.8118
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46224
PEX26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5127
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6597
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86359
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12607
dorsolateral SC part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09335
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38685
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47445
AR	ChEA Transcription Factor Targets	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.37333
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.92467
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69001
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08904
MOLM-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05799
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02983
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.90655
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3227
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23119
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21649
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869666
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.13153
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10494
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07782
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8551
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05892
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF75D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74617
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18473
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
RVH421	DepMap CRISPR Gene Dependency	1.0	2.74449
EZH2	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4ZB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61598
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6587
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98768
SC-5278 (CHEK2)	NURSA Protein Complexes	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57447
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24906
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33514
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99218
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65387
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42145
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61168
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05128
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90195
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4227
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11794
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.55031
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1199
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893463
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10237
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3816
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77317
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6316
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86416
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1226
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67609
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.782
Olfactory transduction	KEGG Pathways 2026	1.0	null
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13659
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07411
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18973
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.6936
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	-1.0	-1.17258
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47199
PCCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44838
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	2.91141
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9656
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12997
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61235
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33564
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7388-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.16951
RFXANK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37208
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49067
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.35396
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06679
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20826
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9019
PI4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78769
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99473
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95496
KDELR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61001
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69618
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30062
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9832
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15183
JAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02177
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22715
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66456
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32786
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2777
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75218
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1575
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91773
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15825
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13455
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
NCIH2170	DepMap CRISPR Gene Dependency	1.0	2.17759
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
KARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88446
ZNF573	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06681
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01271
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42089
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26691
Supraspliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.703
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26289
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30541
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53903
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.46446
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78019
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09184
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24273
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4558
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16999
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5693
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.86527
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73707
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911461
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10637
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5975
Lung squamous cell carcinoma_LUSC_TCGA-56-8305-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47005
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05432
LOVO	DepMap CRISPR Gene Dependency	1.0	2.06871
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30982
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42071
membrane	GO Cellular Component Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
AASS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15877
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09518
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
TMEM123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73636
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16942
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84548
SUZ12	ChEA Transcription Factor Targets	1.0	null
GK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43835
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.59074
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74771
CTCF	ENCODE Transcription Factor Targets	1.0	null
DLD1	DepMap CRISPR Gene Dependency	1.0	4.57155
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.49661
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50092
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1933
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1334
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33626
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86685
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79321
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6759
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11377
EZH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21987
TFAP2A	ChEA Transcription Factor Targets	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40649
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69979
layer 2 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13066
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37368
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25938
NTERA-2_CL_D1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6989
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32711
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90776
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89344
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93935
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1099
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30722
Lung adenocarcinoma_LUAD_TCGA-78-7542-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40025
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32632
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66234
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25731
ZFP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52837
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69793
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FBXL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83599
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43025
LPS510	DepMap CRISPR Gene Dependency	1.0	7.91052
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5792
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2128
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74202
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06771
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51693
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.41944
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47525
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.595
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00977
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83007
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42519
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57479
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43Y-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62019
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50547
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95321
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.204
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39338
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
UMUC9	DepMap CRISPR Gene Dependency	1.0	3.40756
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4714
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70563
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	101.85
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41124
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8426
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10886
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37225
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13939
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8936
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01365
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00491
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07246
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87348
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43025
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59162
BT-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03166
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4759
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7902
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89256
LRRC75B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46845
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07134
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869468
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60296
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74755
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0119
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21039
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
ESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64955
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28_knockout_303_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.17438
frontal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.006
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.875116
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25572
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28441
HDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02554
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10028
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11377
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01734
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.32839
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51812
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22289
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01168
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.8672
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45039
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
MECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30218
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28743
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09207
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06743
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2807
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926122
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04563
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02044
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1349
IST-SL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65334
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02545
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20049
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83329
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11794
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7423-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61032
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.094
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1913
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62263
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25469
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.15645
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11794
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6873
MYC	ChEA Transcription Factor Targets	1.0	null
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75984
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81057
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.960799
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1463
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1869
GLB1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88995
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21753
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	3.61614
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942125
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997751
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31986
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30875
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01986
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
Lung adenocarcinoma_LUAD_TCGA-44-3396-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17662
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67887
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922544
IRF1	ChEA Transcription Factor Targets	1.0	null
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48509
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10628
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60705
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.791229
Gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29484
RPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26927
TST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26166
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
HDAC6	ENCODE Transcription Factor Targets	1.0	null
VPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54107
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.36795
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35662
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3773
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31986
ACAD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3749
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91678
HCA1	DepMap CRISPR Gene Dependency	1.0	2.00996
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.65799
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	4.02543
OGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3092
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27232
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57963
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32786
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2157
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57936
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18967
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23822
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10529
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08967
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31277
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09342
Lung squamous cell carcinoma_LUSC_TCGA-33-A4WN-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17104
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A115-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82596
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51382
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04026
Bardet-Biedl syndrome 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.73
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06893
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61415
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50696
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19073
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.2593
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89885
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69093
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32092
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67323
TK10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.1714
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.73328
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88645
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.6612
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870343
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55735
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15106
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20049
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80735
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87054
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20232
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
TEX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41595
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73797
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.378
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09138
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5065
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63008
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921397
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86954
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12408
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15006
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09218
BT549	DepMap CRISPR Gene Dependency	1.0	2.59858
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35807
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43278
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45142
RPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48794
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8815
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882589
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71512
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86915
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06069
JUN	ENCODE Transcription Factor Targets	1.0	null
MDAMB415	DepMap CRISPR Gene Dependency	1.0	3.72525
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01113
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6281
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.3571
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16272
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
RAB35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.756
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43507
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42162
Brain Lower Grade Glioma_LGG_TCGA-HT-7605-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92216
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Coronary artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
MFM223	DepMap CRISPR Gene Dependency	1.0	2.05514
OSRC2	DepMap CRISPR Gene Dependency	1.0	2.26873
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51671
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15916
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10115
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9461
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34079
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16625
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9291
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7542
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57371
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5719
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3517
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.9835
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17435
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28225
MAST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37231
USP2_KO_GDS5079_25_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86666
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02044
mantle zone of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02983
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08206
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25092
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1236
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57021
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.914773
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8637
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12997
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92109
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.65995
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54736
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66657
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7985
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37721
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6349
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1227
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44011
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20971
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84623
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37311
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
NUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7888
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.611
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37062
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24057
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21975
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43848
496100377_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97465
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12123
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94427
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87266
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26576
IMPDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45435
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838364
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80085
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.3713
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32214
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7327
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5067
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1445
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89457
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10028
ZIC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12611
Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5724
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2043
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	1.92225
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20408
FAAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20576
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00986
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.952712
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846427
ACY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3332
Perturb_10395_KD_USP11_SRP200727	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.84736
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01855
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04181
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58394
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5208
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18616
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19096
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46468
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10028
P31FUJ	DepMap CRISPR Gene Dependency	1.0	2.06208
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92803
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16077
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87384
CAAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47501
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67639
PAAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88394
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973029
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52375
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61324
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35478
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851717
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15232
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83714
ERAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47215
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25603
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7111
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55039
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75102
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55654
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11394
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHL1DM	DepMap CRISPR Gene Dependency	1.0	2.41116
ZNF502	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71715
T3M3	DepMap CRISPR Gene Dependency	1.0	2.29553
mantle zone of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67206
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9537
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52059
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.61208
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60115
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87266
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16305
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7622
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44032
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46147
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39921
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.86983
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90885
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81853
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7433-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28147
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OBSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40225
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50001
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
PATU8902	DepMap CRISPR Gene Dependency	1.0	6.03851
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25904
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38331
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64892
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99134
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9894
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67516
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
RCOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73267
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18285
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1659
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35354
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07246
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84426
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06108
CAL120	DepMap CRISPR Gene Dependency	1.0	2.59588
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
SNU349	DepMap CRISPR Gene Dependency	1.0	2.10511
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8939
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13956
CHD1-26751641-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52078
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
SPCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26936
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.56504
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10214
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1127
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.6743
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.469
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10793
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29651
VMRC-RCW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74069
Lung squamous cell carcinoma_LUSC_TCGA-33-4532-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.452
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7916
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
upper basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26904
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37372
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.63808
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05894
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61375
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836972
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10476
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06451
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88552
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50312
Prion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91975
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM20C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83169
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27262
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30301
RTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48882
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69236
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84148
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03812
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44823
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54406
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86873
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7805
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53544
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08569
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1052
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80346
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31721
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95041
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49515
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91539
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39062
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59268
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70944
Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIPK2_knockout_171_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.946205
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75721
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81153
SAP30	ENCODE Transcription Factor Targets	1.0	null
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97003
CELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08673
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29177
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18079
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869666
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06427
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950483
AMMECR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60612
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51489
CW9019	DepMap CRISPR Gene Dependency	1.0	5.10915
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.0704
LIPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65556
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49678
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.09468
PRRC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43409
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67332
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52974
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.898789
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7632-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65012
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	73.6883
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6088
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
496100583_PCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03358
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32764
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05601
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02663
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31819
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6936
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USP2_KO_GSE43517_20_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83626
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3402
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3014
STC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46208
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5534
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15024
HTATSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08915
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5793
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91112
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.5546
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17435
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
Sensory Perception	Reactome Pathways 2024	1.0	null
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62708
Uterus-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	2.04124
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07428
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
FGFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11129
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73913
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13998
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03765
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	114.273
mantle zone of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14939
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35661
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3356
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12386
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2404
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56835
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.2203
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67303
Intermediate reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29508
sublayer 6b of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13066
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.39892
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0461
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76924
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7035
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30083
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02446
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41606
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.8982
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16305
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32966
CHP212	DepMap CRISPR Gene Dependency	1.0	3.49968
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03654
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07291
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29064
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53603
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937405
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
parabrachial complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22846
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07488
MOSPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32749
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52078
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45742
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
Parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5534
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
PBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06321
SW403	DepMap CRISPR Gene Dependency	1.0	2.0465
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.851044
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0995
mantle zone of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22846
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64582
HSC3	DepMap CRISPR Gene Dependency	1.0	3.64932
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58007
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0823
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84631
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44823
Prostate adenocarcinoma_PRAD_TCGA-CH-5746-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THEM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88385
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0635
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26179
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1586
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19004
ERICH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13721
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09449
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39704
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00835
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20929
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Y-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5729
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10476
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	DepMap CRISPR Gene Dependency	1.0	2.89694
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3622
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14237
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9534
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16115
mantle zone of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31884
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43612
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34137
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.14668
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33069
HS683	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	13.6817
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4317
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.95721
biological regulation	GO Biological Process Annotations 2015	1.0	null
CALR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.937
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48511
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82646
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45621
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44903
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13797
intermediate stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6845
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23422
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32246
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42982
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48644
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.880493
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80724
TRIM28_knockout_301_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.89425
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 5 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03926
molecular_function	GO Molecular Function Annotations 2015	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2081
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.8161
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62S-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0688
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22388
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3252
GSE224678_1_v_0_samhd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0114
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870999
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4071
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68669
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03775
E2F1	ChEA Transcription Factor Targets	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68127
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56874
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.681461
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43147
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26904
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09342
GPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37875
LS1034	DepMap CRISPR Gene Dependency	1.0	4.99554
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
Medulla, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02983
dorsal part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14939
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18973
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70191
biological_process	GO Biological Process Annotations 2015	1.0	null
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48381
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78994
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17686
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.65007
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61481
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.8759
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95195
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1938
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77842
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6804
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
Brain Lower Grade Glioma_LGG_TCGA-FG-7641-01B-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08615
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2337
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5287
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71324
U-CH2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84921
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7522
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9161
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
Perturb_14089_KO_SMARCA2_SRP295674	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.335
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.434
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06679
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71754
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75949
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61069
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982966
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.3448
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
JUND	ENCODE Transcription Factor Targets	1.0	null
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38412
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916085
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66661
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14237
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0767
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05634
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26289
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22437
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11315
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20954
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5435
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4701
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51999
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8294
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39808
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45631
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.38259
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10004
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20042
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0848
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01995
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.61546
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15079
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7578
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39448
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05713
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52183
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19386
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24136
OV7	DepMap CRISPR Gene Dependency	1.0	2.19869
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.28384
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5012
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6738
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65127
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61223
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.14469
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5742
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44908
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26849
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.70472
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21093
SOX2	ChEA Transcription Factor Targets	1.0	null
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67503
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.207
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38107
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47735
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07246
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10960568-mjad044_supplemental_file.pdf-46-NFYC-AS1_NFYC	Rummagene Transcription Factor Associations 2026	1.0	null
Thyroid lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
COQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27846
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13514
intermediate stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41421
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
SPRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90627
mantle zone of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24273
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2539
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63144
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78363
CERS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20788
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24425
BOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83226
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60559
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS34	DepMap CRISPR Gene Dependency	1.0	3.36353
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42004
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838364
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19826
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28438
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95526
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71699
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68166
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16363
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.56887
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02446
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88712
KLK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85229
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03654
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60657
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40728
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36154
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70993
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76977
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951709
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03654
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911461
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00516
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45058
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53193
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
FAM234A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8363
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33564
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91657
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31249
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87195
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39108
GPATCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23139
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00501
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15142
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42089
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87054
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63385
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53903
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80881
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92211
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93347
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.60091
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55439
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31986
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.8491
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842248
cell part	GO Cellular Component Annotations 2015	1.0	null
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44102
rhombomere 7	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01966
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.891
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.802
layer 6 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37092
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4991-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL72	DepMap CRISPR Gene Dependency	1.0	2.09622
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04525
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01966
STAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31086