association	dataset	threshold value	standardized value
IOMMLEE	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.56979
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24686
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7128
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40194
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47065
CTV1DM	DepMap CRISPR Gene Dependency	1.0	4.07172
CD83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7158
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16466
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0057
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16258
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05318
CCER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37313
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60619
Schinzel Giedion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1463	DepMap CRISPR Gene Dependency	1.0	2.14008
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938558
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.0969
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5287
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38019
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835601
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87814
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73739
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931176
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15483
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78952
PANC0203	DepMap CRISPR Gene Dependency	1.0	2.07941
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10243
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17436
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02346
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18781
lymph node	HPA Tissue Gene Expression Profiles	1.0	0.863175
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8077
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883791
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5088
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39567
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
DLD1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12139
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0854
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1148
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6277
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05664
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3158
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3076
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84069
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
Brain Lower Grade Glioma_LGG_TCGA-FG-A60K-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67539
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48079
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59092
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67381
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9438
GPR89A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92025
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6451
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03545
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09221
Prostate adenocarcinoma_PRAD_TCGA-M7-A720-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8345
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17279
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.12124
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3087
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35783
Lung squamous cell carcinoma_LUSC_TCGA-68-7755-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3535
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4866-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A44S-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67227
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37366
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.36408
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6907
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4894-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.914994
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.1893
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15219
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29898
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53084
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.46069
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03272
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943232
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07042
cell part	GO Cellular Component Annotations 2015	1.0	null
ANKRD16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85327
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7US-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.37245
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.50883
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.783025
HT29	Achilles Cell Line Gene Essentiality Profiles	1.0	1.60989
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58907
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8137
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91433
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26018
CORL279	DepMap CRISPR Gene Dependency	1.0	5.71934
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2309
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56507
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8029
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42142
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6441
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51117
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6443
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7545
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03709
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8909
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.64172
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.997
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64104
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7097
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05318
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943464
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3463
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.39374
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48413
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14739
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.857
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23232
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44579
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5956
K562	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07777
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843796
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8555
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC30A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04316
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999663
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06934
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1083
SLR26	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24232
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2432
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OPLAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69839
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIJK	DepMap CRISPR Gene Dependency	1.0	4.10359
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05318
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40092
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.19227
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5294
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3320-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06215
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.72833
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33031
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989258
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58441
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27801
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7907
HSPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76502
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5668
CEBPB	ENCODE Transcription Factor Targets	1.0	null
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16715
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-TM-A84S-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4446
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22713
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50175
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23933
Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55461
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4014
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964936
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914336
Lung adenocarcinoma_LUAD_TCGA-50-8457-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BMAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6874
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.968042
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13832
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01236
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21101
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16466
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.35238
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3086
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39569
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69879
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
Brain Lower Grade Glioma_LGG_TCGA-FN-7833-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85181
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07715
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09012
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96565
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.493
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.860582
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7947
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26852
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15208
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836225
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5861
CLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98641
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75942
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57904
Lung adenocarcinoma_LUAD_TCGA-44-7672-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3855
YKG1	DepMap CRISPR Gene Dependency	1.0	2.36437
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.597
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5406
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4164-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5748
IGROV1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0465
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81921
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13697
Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4077
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3912
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99661
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
GTF2IRD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02323
Lung squamous cell carcinoma_LUSC_TCGA-66-2794-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26008
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78852
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10731
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34197
OVCAR8	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.5442
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48914
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.598
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	179.7
Thymus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0195
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7653
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48079
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.10317
ABTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98082
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1914
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12272
CDC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84519
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39038
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72929
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4639-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCCMPNST1C1	DepMap CRISPR Gene Dependency	1.0	2.01147
RERFLCAI	CCLE Cell Line Gene CNV Profiles	1.0	1.32744
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19185
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35691
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5296
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.83649
Acute Myeloid Leukemia_LAML_TCGA-AB-2867-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.2257
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82375
SUM229PE	DepMap CRISPR Gene Dependency	1.0	4.15426
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84706
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2847
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.7415
MGST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5133
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0686
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17013
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830272
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9523
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5789
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2633
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08994
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6887
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.4169
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Signaling by GPCR	Reactome Pathways 2014	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mRNA_STAT3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59246
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17322
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07351
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853467
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.39245
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24943
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64428
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48607
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926175
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3321
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842037
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914607
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.055
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.1675
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
L1236	DepMap CRISPR Gene Dependency	1.0	2.19271
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
Sarcoma_SARC_TCGA-X6-A7WA-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_12Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.54162
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1245
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.20188
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00822
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36859
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
membrane part	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100479_FWM_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99176
SMARCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82676
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4117-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3252
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1185
RASGRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91374
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5384
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4876
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24097
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3182
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.61
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3183
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
496100295_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30934
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52357
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
prostate	HPA Tissue Protein Expression Profiles	1.0	1.74409
ATOH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56848
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92235
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978581
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22991
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9547
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V3-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1972
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54516
CTSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67338
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93334
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.464
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.56
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07054
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15525
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01426
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.72292
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5404
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3638
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80738
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4892-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MS-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90326
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.4877
IRX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07437
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07715
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18781
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2998
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51445
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14624
RCOR1	ChEA Transcription Factor Targets	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4874
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53416
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4094
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06477
SPATA33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65692
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.45736
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	1.0	5.1982
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.36132
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3266
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74847
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21035
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5164
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NUDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88885
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36341
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J3-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92235
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5818
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09477
CHD1	ENCODE Transcription Factor Targets	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1584
Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.83979
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94687
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77498
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4122
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.147
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6001
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832182
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50616
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84884
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4998-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SLC25A46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79928
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XI-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7599
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24679
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HJ-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1592
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2924
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84936
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0245
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22492
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0038
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.8105
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66389
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.593
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11573
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4568
SEC31B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25044
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1152
Rectum adenocarcinoma_READ_TCGA-AG-3592-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68714
thorax	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
response to stimulus	GO Biological Process Annotations 2015	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999663
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41444
SW579	DepMap CRISPR Gene Dependency	1.0	3.3667
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06946
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5541
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7209
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5089
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6339
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_knockout_301_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.4577
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MT-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9347
mRNA_SMAD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SNU16	DepMap CRISPR Gene Dependency	1.0	2.03076
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39687
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68043
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27235
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6208
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.91983
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83484
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4838-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1393
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
HT115	DepMap CRISPR Gene Dependency	1.0	2.03135
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Developmental coordination disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
MYL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53356
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7301-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACHN	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.80438
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0021
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3037
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
Brain Lower Grade Glioma_LGG_TCGA-HT-7605-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEL	DepMap CRISPR Gene Dependency	1.0	2.76022
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41636
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48622
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6635
TEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4344
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00773
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38294
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0698
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0109
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74992
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858785
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4173
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17071
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83651
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11351
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58192
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	82.2468
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13757
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26343
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6103
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67853
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6751
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95602
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61536
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4368
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67309
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867007
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CASKI	DepMap CRISPR Gene Dependency	1.0	5.55606
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27847
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4607
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.38509
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
EWS502	DepMap CRISPR Gene Dependency	1.0	2.41074
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.2593
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1009
ZBTB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73625
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12959
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	2.49914
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2835
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06683
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8394
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6743
PIGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81825
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19229
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834567
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14121
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1545
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88592
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982563
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16431
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.581
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48129
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912414
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80691
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4327-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3370-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880992
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86333
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.81397
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69447
Brain Lower Grade Glioma_LGG_TCGA-DB-A64R-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
SNU213	DepMap CRISPR Gene Dependency	1.0	2.17219
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00599
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7347
LHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96605
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.391
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824703
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37664
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91596
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM19	Achilles Cell Line Gene Essentiality Profiles	1.0	1.51604
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06691
Cerebellar hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867007
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05322
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3946
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59125
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5106
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35841
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90622
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03841
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.13975
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8859
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920798
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17182
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
COGN305	DepMap CRISPR Gene Dependency	1.0	2.5118
Kidney Chromophobe_KICH_TCGA-KL-8332-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10523
SF295	DepMap CRISPR Gene Dependency	1.0	2.592
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9452
HCC1187	DepMap CRISPR Gene Dependency	1.0	5.24194
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8425-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64559
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
496100297_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.60346
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0704
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3993
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4584
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3333
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47552
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1909
Lung adenocarcinoma_LUAD_TCGA-55-8089-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1082
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.161
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4463
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9648
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901237
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835093
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27787
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12248
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86806
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.814
496100600_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.39111
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6809
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32154
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.371
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46042
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THP1	DepMap CRISPR Gene Dependency	1.0	8.23115
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LEPROT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51776
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09837
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LH-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2331
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
Lung squamous cell carcinoma_LUSC_TCGA-60-2704-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.4416
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59602
KP3	DepMap CRISPR Gene Dependency	1.0	2.4949
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85981
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33109
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11493
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885342
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21014
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8332
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12801
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22167
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.4954
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6465
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21239
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0997
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4782
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Gene_name_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
PANC1005	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.41815
Lung adenocarcinoma_LUAD_TCGA-55-6979-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and neck cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55457
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69747
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.6822
MRPL50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64013
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848075
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949144
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6725
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28424
Lung adenocarcinoma_LUAD_TCGA-55-7574-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58166
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.69024
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36695
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11937
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59371
Lung adenocarcinoma_LUAD_TCGA-75-6212-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835753
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V6-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68862
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
KYO1	DepMap CRISPR Gene Dependency	1.0	2.28177
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.793839
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14774
Kabuki syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834567
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MK-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62509
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834567
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6783
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17182
SHI1	DepMap CRISPR Gene Dependency	1.0	2.87828
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8239
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76578
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928459
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.7792
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18919
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845866
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02693
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2976
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93574
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3938
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9273
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.68909
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4228
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88645
DDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04298
COA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86185
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55027
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912089
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3115
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44223
Olfactory transduction	KEGG Pathways 2026	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3352
MBD3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65319
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77051
Lung adenocarcinoma_LUAD_TCGA-MP-A4TH-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44672
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.635743
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8309
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912473
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.844929
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6353
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50076
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12756
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7480-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
C22orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7588
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94831
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.028
NOS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69046
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17988
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67438
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNT34	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37365
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6907
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4916-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07843
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48831
TGIF2LY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75684
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85888
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38866
Sensory Perception	Reactome Pathways 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2159
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20388125-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2915-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1271	DepMap CRISPR Gene Dependency	1.0	2.45492
SW48	DepMap CRISPR Gene Dependency	1.0	3.87389
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69891
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54362
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54959
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.40118
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0111
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.5973
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35645
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.778
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38309
ARAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14169
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837707
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13757
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9496
FOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21957
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	79.7299
TMEM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77881
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.8472
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A50Z-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64204
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80135
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89297
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68257
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.4045
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27972
OCUM1	DepMap CRISPR Gene Dependency	1.0	4.40476
CME1	DepMap CRISPR Gene Dependency	1.0	4.60083
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1159
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.8722
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.655879
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04972
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9691
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2728
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.626
Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31876
KARPAS299	DepMap CRISPR Gene Dependency	1.0	2.0867
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Ensemble_gene_ID_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32502
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9548
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13817
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTP4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26814
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66343
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827633
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11927
MIA-PACA-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3508
RB1_KD_GSE50532_659_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876787
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94728
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15066
ARHGEF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46838
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
A549	DepMap CRISPR Gene Dependency	1.0	2.12866
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02271
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9709
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4095
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6469
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85437
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42997
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.85539
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12871
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9022
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78656
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3307
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996184
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4171
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78878
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.86277
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16409
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845866
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37143
P2RX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83389
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.46588
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21548
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07547
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0657
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855607
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17494
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44741
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978711
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26263
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56766
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8597
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.745
FOXL2NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52779
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGR39	Achilles Cell Line Gene Essentiality Profiles	1.0	1.52733
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80691
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18108
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2754
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96548
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0983
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.65887
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.27827
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5392
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07289
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52265
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84205
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.297
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973368
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9805
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0067
Brain Lower Grade Glioma_LGG_TCGA-DH-A66F-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
FBXW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59547
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.2106
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.862
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4596
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5116
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19235
FLI1	ChEA Transcription Factor Targets	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16036
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1894
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30642
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.83649
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.846
signal transduction	GO Biological Process Annotations 2015	1.0	null
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1538
RAB3GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58578
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.0045
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20218
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06194
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYLA	DepMap CRISPR Gene Dependency	1.0	2.7047
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8652
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.27556
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5961
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986545
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53655
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934711
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0931
SUIT2	DepMap CRISPR Gene Dependency	1.0	2.91219
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60814
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14355
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
HPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57797
ZNF836	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66064
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909612
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.819137
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5489
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4845
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3194
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03604
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.3002
EJM	DepMap CRISPR Gene Dependency	1.0	5.62319
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56517
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37181
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5993
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2393
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87444
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65522
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980623
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948535
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4113-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4353-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909054
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.822
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69029
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87093
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
Lung squamous cell carcinoma_LUSC_TCGA-43-8116-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.8519
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.897382
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45269
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.967214
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37366
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
FOS	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48622
17823238-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62171
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3081
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42572
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13757
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5232
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
PARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23991
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6769
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923551
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00538
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11931
CPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92287
receptor activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6996-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85262
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73399
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17102
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A9DB-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40318
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14833
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4282
MRPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87542
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1949
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10464
membrane	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17871
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9215
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.276
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948185
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8059
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38298
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymus-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	4.00877
EHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21695
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82646
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4873
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13227
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91784
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2491
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.0962
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30632
Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70361
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83334
mRNA_TUBA1A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78096
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5331
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8609
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14907
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03915
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DU4475	DepMap CRISPR Gene Dependency	1.0	4.14106
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7086-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5782
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9218
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.72598
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.049
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0668
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	117.804
RH28	DepMap CRISPR Gene Dependency	1.0	2.05124
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55025
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867007
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88499
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.66771
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
JUND	ENCODE Transcription Factor Targets	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31217
DYNC2I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05314
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.74437
NB4	DepMap CRISPR Gene Dependency	1.0	2.61046
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9605
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93963
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1772
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3798
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7041
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.884
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.743278
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5392
PMC8108288-gutjnl-2020-321731supp004.xlsx-LPS_stimulation-gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84944
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.4897
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.54615
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8912
DTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32094
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31571
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58739
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2389
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0338
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5102-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7781
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27847
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08442
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65059
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.1954
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.46679
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.855878
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6906
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2182
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65729
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56988
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98663
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922522
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98663
TSSK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03578
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0433
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02405
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68281
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35722
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57371
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9189
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.6855
FBXO38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82559
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940816
ESRRA_01_280	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.72391
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62591
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1285
Prostate adenocarcinoma_PRAD_TCGA-HC-7817-01B-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07636
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.3639
Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.816
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1947
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46663
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71125
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.77009
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91678
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2064
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56149
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38184
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73595
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.17656
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.74
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828264
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37823
biological regulation	GO Biological Process Annotations 2015	1.0	null
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93778
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31276
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3698
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.95706
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26779
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48046
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38256
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7716
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48106
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905192
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73Q-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
CYB5D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96507
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2919
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.933658
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18785
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
HUNS1	DepMap CRISPR Gene Dependency	1.0	5.26566
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04254
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
U87MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.81952
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36029
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04559
F8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52433
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923551
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00764
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45469
C99	DepMap CRISPR Gene Dependency	1.0	4.53006
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30136
NOZ	DepMap CRISPR Gene Dependency	1.0	3.16728
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0839
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03898
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60832
SW1417	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.64811
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14268
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52162
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855047
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.783
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.938768
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6389
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7438
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06913
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5933
Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48079
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1164
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1411
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95311
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.148
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18781
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14443
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25653
ABCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39236
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.00997
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.2963
COX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33278
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.792
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923551
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70224
ARL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79443
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24906
NB14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0429
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59713
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96362
MCF7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39306
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15958
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.75977
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.9901
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08096
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3382-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1105	DepMap CRISPR Gene Dependency	1.0	2.01005
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RANBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57626
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965388
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A51Y-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4431
TM9SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84777
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56451
SYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66835
hsa-miR-145	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
OPM2	DepMap CRISPR Gene Dependency	1.0	2.49746
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94638
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49799
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15489
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65872
Adrenocortical carcinoma_ACC_TCGA-OR-A5LR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RETREG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51505
BT474	Achilles Cell Line Gene Essentiality Profiles	1.0	1.43179
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45881
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881404
CANT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.26565
ZFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14807
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.3064
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888228
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0752
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3277
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98663
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01487
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.154
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947167
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13817
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5856
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9226
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6131
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2045
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6878
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06396
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52737
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17147
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02841
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7208
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3454
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21035
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25134
PYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02779
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA_01_288	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60532
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24902
thymus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42986
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.38837
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30117
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70863
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64832
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0421
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867007
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68546
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A463-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6701
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6131
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
ZR7530	Achilles Cell Line Gene Essentiality Profiles	1.0	1.77024
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83024
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1575
RFX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.941
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46482
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0765
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06194
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.664782
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
CER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04528
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9175
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7095
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5856
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.78
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.52075
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.79592
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.48266
OCIM2	DepMap CRISPR Gene Dependency	1.0	2.8728
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827633
SKMEL24	DepMap CRISPR Gene Dependency	1.0	2.46647
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35663
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8523
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.972307
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.771
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923551
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832341
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8806
FAM110A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85716
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86868
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71257
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986545
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56097
Sarcoma_SARC_TCGA-DX-A48J-01A-21R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.37016
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32552
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891427
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81016
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4775-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81369
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9306
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60299
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
ARHGAP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2901
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06962
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83792
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.261
MPZL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8392
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.985443
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.58932
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907097
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08681
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15671
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06194
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0779
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EVSA-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56014
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2504
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8601
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
SCC-25	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
FOSL2	ENCODE Transcription Factor Targets	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29487
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08416
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923551
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58716
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04497
Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
hsa-miR-1206	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07843
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36813