association	dataset	threshold value	standardized value
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1333
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.65926
Distal myopathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.47737
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSN1	DepMap CRISPR Gene Dependency	1.0	2.53358
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933333
single-organism process	GO Biological Process Annotations 2015	1.0	null
CORL47	DepMap CRISPR Gene Dependency	1.0	3.36453
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7689
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.741
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27861
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998484
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54511
NR2E3	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0663
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39423
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13668
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5956
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8606
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90627
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.155
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827027
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38141
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.862429
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851871
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96861
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60523
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967647
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5726
ECC4	DepMap CRISPR Gene Dependency	1.0	2.50652
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
A_CA_04_2009_7dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.41618
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72297
JHH7	DepMap CRISPR Gene Dependency	1.0	2.10032
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02388
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16462
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Unnamed_6_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39704
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0685
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93799
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40992
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931901
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90843
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.604
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10507
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.9
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9312
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3742
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22511
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10901
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29291
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5816
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.529
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09035
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5477
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24354
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870774
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6634
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.993835
RAJI	DepMap CRISPR Gene Dependency	1.0	2.01181
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2296
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.840576
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03749
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78124
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1709
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1749
Trachea-ionocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.0526412
SW837	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189336_1_v_0_nitric oxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	1.0	2.40699
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_5_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
odorant binding	GO Molecular Function Annotations 2015	1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0572
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.837907
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8646
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851871
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.75699
TE6	CCLE Cell Line Gene CNV Profiles	1.0	1.36591
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35003
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.72647
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09035
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory transduction	KEGG Pathways 2026	1.0	null
Specific language impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15516
signal transduction	GO Biological Process Annotations 2015	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8554
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6768
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879693
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10634
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843533
GSE147240_3_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77397
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828765
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.732327
Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0033
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL105	DepMap CRISPR Gene Dependency	1.0	2.31061
IMR-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8502
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4894
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0534
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863062
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39704
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57204
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24439
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41172
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2147
HCC38	DepMap CRISPR Gene Dependency	1.0	2.57268
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8078
neurological system process	GO Biological Process Annotations 2015	1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11525188-41588_2024_1893_MOESM4_ESM.xlsx-Supplementary_Table_4-Supplementary_Table_4_NSD2_signature_genes_and_GREAT_genes_associated_with_NSD2-dependent_and_NSD2-independent_AR_binding_sites_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924434
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1368
GSE147240_3_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5615
H3K9me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21278
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3792
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919508
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8889
SKMEL31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37131
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0846
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3074
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3175
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2237
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14198
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6554
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19667
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58171
MG63	DepMap CRISPR Gene Dependency	1.0	2.52968
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26754
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1452
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
HCA1	DepMap CRISPR Gene Dependency	1.0	2.49915
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	3.53166
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
SNU475	CCLE Cell Line Gene CNV Profiles	1.0	2.29188
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851871
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5007-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.934
EFM19	DepMap CRISPR Gene Dependency	1.0	2.99294
CS1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0319
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10099
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5578
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4013
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841927
KPL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49757
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.69775
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7356
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.736171
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858372
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71206
GSE158320,GSE183351_2_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2464
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03345
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27391
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3736
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	2.00648
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5673
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.48899
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979124
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4791
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-LGG_MYB_L1_deletions-Unnamed_2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0798
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04982
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17805
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2607
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933286
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.1012
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9548
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0769
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5852
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07581
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33887
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2288
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7149
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.3395
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.51187
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51152
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.899
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.62804
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13345
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS26	DepMap CRISPR Gene Dependency	1.0	2.04824
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8209
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.581895
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949303
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9799
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26011
NCI-H2029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.4188
MELHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36116
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919508
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6693
SF295	DepMap CRISPR Gene Dependency	1.0	2.29053
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96818
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.40203
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.6001
MKN45	DepMap CRISPR Gene Dependency	1.0	2.88633
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28455
TE11	CCLE Cell Line Gene CNV Profiles	1.0	1.42737
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01804
CAL29	DepMap CRISPR Gene Dependency	1.0	8.1983
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.636
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.55891
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04437
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3075
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9481
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4505-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89765
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4028
Fetal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2231
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77895
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.99952
YAMATO	DepMap CRISPR Gene Dependency	1.0	2.46975
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Treacher Collins syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.167
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.411
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1986
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0211
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13345
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25551
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4786
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.225
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3337
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52341
Signal Transduction	Reactome Pathways 2014	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8948
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2047
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8756
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01201
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21278
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851871
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08947
KLF1	ChEA Transcription Factor Targets	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5518-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9708
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	1.5821
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.88226
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.564
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13487
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.414
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OE21	CCLE Cell Line Gene CNV Profiles	1.0	1.68109
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967647
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34973
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0337
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16783
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841364
Signaling by GPCR	Reactome Pathways 2014	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875995
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80135
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.36041
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.837907
TFAP2A	ChEA Transcription Factor Targets	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
ESR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65575
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841927
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4912
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1129
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.25
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8579
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3953
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5261
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2688
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63455
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87918
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896244
BXPC3	DepMap CRISPR Gene Dependency	1.0	2.39575
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982928
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17073
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06941
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896244
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-0.837907
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1266
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1353
NCIH1838	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2752
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.837907
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6422
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10293
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0867
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5696
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8377
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850784
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6152
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4305
KYSE150	DepMap CRISPR Gene Dependency	1.0	2.61083
IPF1	MotifMap Predicted Transcription Factor Targets	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Treacher Collins syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893318
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.07606
GSE240444_2_v_3_idasanutlin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4169
membrane	GO Cellular Component Annotations 2015	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3251
EHEB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KATOIII	DepMap CRISPR Gene Dependency	1.0	3.28737
Dyscalculia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4294
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34013
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.994
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.4572
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2422
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851871
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0151
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931901
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0977
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75114
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48647
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
smoking cessation	GAD Gene-Disease Associations	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07917
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21278
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2537
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28738
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5657
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.1283
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34013
biological regulation	GO Biological Process Annotations 2015	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8194
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87008
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6174
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.849
NCIH716	DepMap CRISPR Gene Dependency	1.0	2.37114
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1249
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6957
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.43093
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
SUM159PT	DepMap CRISPR Gene Dependency	1.0	2.13235
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81205
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65296
GP5D	DepMap CRISPR Gene Dependency	1.0	3.61081
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8386
speech-language disorder-1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESO26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4713
JHH-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.69967
KPNYN	DepMap CRISPR Gene Dependency	1.0	4.17783
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.0951
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1964
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16709
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37499
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15516
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68243
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0399
GSE182680,GSE182683_7_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Megaloblastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
MEL202	DepMap CRISPR Gene Dependency	1.0	3.59431
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.0321
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1172
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Chromosome 2p16.1-p15 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.89
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5525
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0698
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5639
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS683	DepMap CRISPR Gene Dependency	1.0	2.01687
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7463
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6038
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46402
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1908
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7576
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07039
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.7934
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89614
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23829
NP8	DepMap CRISPR Gene Dependency	1.0	3.00314
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0895
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
PMC10915192-ab-23-0304-Supplementary-Table-S6.pdf-13-SOX6_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147240_3_v_1_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05288
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
SKNFI	DepMap CRISPR Gene Dependency	1.0	4.58599
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32977
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38205
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1866
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.41579
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	2.33082
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70322
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9369
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839252
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03748
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87008
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13345
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09065
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30578
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.74091
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5828
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51601
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896244
LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904293
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3463
cellular_component	GO Cellular Component Annotations 2015	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2853
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2555
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4987-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kelly	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.28719
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28075
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967647
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.88113
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0692
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6698
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1391
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21278
cell part	GO Cellular Component Annotations 2015	1.0	null
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7602
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12373
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986385
EZH2	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40643
FHOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37771
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985325
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59441
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99564
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7999
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4109
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50549
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3645
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9815
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4595
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1395
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51197
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_3_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
USP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71062
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.113
SHMAC5	DepMap CRISPR Gene Dependency	1.0	3.42041
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78288
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0407
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59941
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6561
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOS2	DepMap CRISPR Gene Dependency	1.0	5.02353
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895666
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
KML1	DepMap CRISPR Gene Dependency	1.0	4.5988
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
KYSE-220	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2134
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03942
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28813
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.21587
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	5.03165
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.36674
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45661
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51359
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59957
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30903
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3024
Familial hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
EFO27	DepMap CRISPR Gene Dependency	1.0	2.30761
Mammary-fibroblast of breast	Tabula Sapiens Gene-Cell Associations	1.0	4.22183
NCIH2110	DepMap CRISPR Gene Dependency	1.0	3.31946
PMC3919509-NIHMS471461-supplement-3.xls-Table_S1-ZNF33A_ZNF33A	Rummagene Transcription Factor Associations 2026	1.0	null
WM3772F	DepMap CRISPR Gene Dependency	1.0	2.28527
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.451
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886497
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN74	DepMap CRISPR Gene Dependency	1.0	3.46295
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1574
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24439
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874388
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35959
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.04713
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87008
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LP1	DepMap CRISPR Gene Dependency	1.0	3.89734
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7086-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.765
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4452
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.901381
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17432
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.847
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.716508
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1708
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30687
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.837907
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18644
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28083
A388	DepMap CRISPR Gene Dependency	1.0	3.96385
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8818
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.74171
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8243
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.79646
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9226
PPARD	ChEA Transcription Factor Targets	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.55771
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1083
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846191
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.834668
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18221
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.95025
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24439
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850784
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Hyaline body myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
MID1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.771
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6212
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7269
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.528
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6181
Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10293
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5838
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51601
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.464
H3K9me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TC71	DepMap CRISPR Gene Dependency	1.0	3.32904
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07039
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5279
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.40625
biological_process	GO Biological Process Annotations 2015	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841364
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870774
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0574
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2	ChEA Transcription Factor Targets	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13534
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6148
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13258
response to stimulus	GO Biological Process Annotations 2015	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20309
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dopamine beta-hydroxylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44406
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.40225
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.829831
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1372
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34369
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9328
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12997
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01219
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKNAS	DepMap CRISPR Gene Dependency	1.0	3.01052
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.98843
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13345
L33	DepMap CRISPR Gene Dependency	1.0	4.14936
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3759
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13982
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.7123
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9323
H9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8747
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893751
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
SKPNDW	DepMap CRISPR Gene Dependency	1.0	4.05499
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24527
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72508
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7701
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2275
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09035
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9841
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224131_2_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06881
membrane part	GO Cellular Component Annotations 2015	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30377
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	1.93015
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.80462
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7134
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.50086
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8393
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67207
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6675
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
sensory perception	GO Biological Process Annotations 2015	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9709
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.209
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07586
SNU-475	COSMIC Cell Line Gene CNV Profiles	1.0	2.10038
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4103
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6199
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10532
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2687
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGA1	DepMap CRISPR Gene Dependency	1.0	5.26273
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
receptor activity	GO Molecular Function Annotations 2015	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35396
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60397
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0558
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
A2780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.198
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.831
binding	GO Molecular Function Annotations 2015	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06481
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.0384
DMRT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6312
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37615
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8044
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5258
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08771
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
OV7	DepMap CRISPR Gene Dependency	1.0	3.26585
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70488
KU1919	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44229
Sensory Perception	Reactome Pathways 2024	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28759
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE143692_0_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.25669
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4349
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13534
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4788
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2593
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2777
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.32495
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.921221
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7141
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4617
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46314
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5221
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851871
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.39931
Sly syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4444
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26972
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.39372
HMY1	DepMap CRISPR Gene Dependency	1.0	2.0194
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985325
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4069
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1621
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841364
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20097
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6003
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23887
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2477
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC1	DepMap CRISPR Gene Dependency	1.0	2.2365
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931901
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5296
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919508
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.962905
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05785
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PECAPJ15	DepMap CRISPR Gene Dependency	1.0	2.00146
NCI-H1838	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.38669
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU1033	CCLE Cell Line Gene CNV Profiles	1.0	1.78253
system process	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982318
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null