association	dataset	threshold value	standardized value
binding	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	2.25655
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51177
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31438
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05038
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18799
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.34725
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29522
PMC10185556-41467_2023_38439_MOESM3_ESM.xlsx-ST19_MR_results-nearest_gene_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17056
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92717
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7184
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27774
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20488
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58494
TC71	DepMap CRISPR Gene Dependency	1.0	4.17284
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9733
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2787
Loneliness (MTAG)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26542
COR-L95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.909337
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09048
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862033
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.50485
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37773
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02557
SW954	DepMap CRISPR Gene Dependency	1.0	2.30708
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7782
A549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BACH1	ENCODE Transcription Factor Targets	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62731
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
IST-SL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMCUB1	DepMap CRISPR Gene Dependency	1.0	2.27543
FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13431
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SKPNDW	DepMap CRISPR Gene Dependency	1.0	3.33668
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03166
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76563
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63771
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8084
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854213
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.52621
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1618
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC27	DepMap CRISPR Gene Dependency	1.0	4.85033
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930693
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41392
HEC108	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7293
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4997
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03167
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.9452
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21989
KYSE30	DepMap CRISPR Gene Dependency	1.0	3.20714
TEN	DepMap CRISPR Gene Dependency	1.0	2.38524
H4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9173
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43573
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
SH10TC	DepMap CRISPR Gene Dependency	1.0	6.13648
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7433
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919009
cell part	GO Cellular Component Annotations 2015	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51253
RT112	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69433
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37065
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3323
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4771
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	2.04316
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.13012
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50549
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8755
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.743
biological regulation	GO Biological Process Annotations 2015	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0033
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39542
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1105
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8455
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87044
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831388
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.993441
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5129
ATM_knockout_75_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.61248
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7758
Fra-1_KO_GDS5078_402_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03068
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.988702
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74447
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59963
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46947
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	2.14966
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92934
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67774
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	4.22467
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.745
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.627
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848372
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853423
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86333
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29568
Umbilical vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57866
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3447
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0942
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3329-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72524
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21493
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910189
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55795
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73444
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CW9019	DepMap CRISPR Gene Dependency	1.0	2.22806
RHJT	DepMap CRISPR Gene Dependency	1.0	4.58541
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36198
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21238
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915388
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15127
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0731
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04558
PMC12016830-crt-2024-667_S3_Table.pdf-9-RFX5_RFX5	Rummagene Transcription Factor Associations 2026	1.0	null
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.981785
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.34755
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5409
Ability to confide in someone	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.704576
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30163
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20075
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86127
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908355
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916518
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.884879
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10215
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11018
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9503
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100546_TCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42655
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43174
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45887
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9722
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34249
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.70995
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6754
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2701
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
IPC298	DepMap CRISPR Gene Dependency	1.0	2.7975
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89961
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2398
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33808
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862033
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01504
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15017
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848548
GP5D	DepMap CRISPR Gene Dependency	1.0	2.41666
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7836
Olfactory transduction	KEGG Pathways 2026	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06711
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07058
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.64399
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4754
496100454_FWM_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09114
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3611
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02687
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.221
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04582
CMLT1	DepMap CRISPR Gene Dependency	1.0	3.31294
JM1	DepMap CRISPR Gene Dependency	1.0	3.8644
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5615
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09649
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.01656
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15944
LCLC97TM1	DepMap CRISPR Gene Dependency	1.0	4.2321
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06718
cingulate gyrus, frontal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85864
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.913944
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8551
RB1_KD_GSE50532_591_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71867
Loneliness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
RCOR1	ChEA Transcription Factor Targets	1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30087
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45887
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87024
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.529
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886629
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8716
TFAP2A	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977555
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1436
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cajal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
MOLM14	DepMap CRISPR Gene Dependency	1.0	3.5242
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921466
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.94098
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81725
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850811
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70885
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31158
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.38603
496100560_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.96448
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4101-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96019
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889876
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09821
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28284
Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39504
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19327
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.843396
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.847959
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02673
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992002
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19327
CHD1	ENCODE Transcription Factor Targets	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4656
SNU387	DepMap CRISPR Gene Dependency	1.0	2.59879
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3051
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9284
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BXPC3	DepMap CRISPR Gene Dependency	1.0	2.3151
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.16603
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.41068
GATA2_01_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58648
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.873127
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3551
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944305
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.68038
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19482
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8571
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1724
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11848
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0247
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7856
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5576
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0743
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8913
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.968
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10717
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32567
Signaling by GPCR	Reactome Pathways 2014	1.0	null
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
sensory perception	GO Biological Process Annotations 2015	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918625
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64833
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-2.288
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6723
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3755
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4105
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.36495
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51489
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.78533
response to stimulus	GO Biological Process Annotations 2015	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52816
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990018
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86333
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35329
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41217
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.133
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29044
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10683
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29522
WM1799	CCLE Cell Line Gene CNV Profiles	1.0	2.24022
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29522
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2005
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93349
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.73352
SUIT2	DepMap CRISPR Gene Dependency	1.0	2.44875
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7088
Atypical autism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.13141
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03167
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06238
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86186
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992002
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.194
496100341_TCx_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28448
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9644
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40393
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0664
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9204
Sarcoma_SARC_TCGA-X6-A7WA-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.82654
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930053
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66453
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2016
496100512_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55882
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23733
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8889
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.582
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07058
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72422
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.23511
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86333
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86186
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.133
Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
NCIH28	DepMap CRISPR Gene Dependency	1.0	3.21248
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53703
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IZ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.301
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887715
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35543
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17129
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2104
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.43282
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5027
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90163
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.46937
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	2.09378
BFTC909	DepMap CRISPR Gene Dependency	1.0	4.47559
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50516
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944305
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00512
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03782
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00104
membrane	GO Cellular Component Annotations 2015	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1542
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930693
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21729
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24705
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86333
G-292_CLONE_A141B1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45732
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33258
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0075
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9389
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8918
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36338
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75532
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.1591
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5190-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13632
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1666
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826509
PSN1	DepMap CRISPR Gene Dependency	1.0	3.15597
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2907
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.957261
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interleukin-6 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0828
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.17173
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81011
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40876
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24616
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61655
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944305
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5322
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991351
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63091
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48414
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00074
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8801
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863941
U2OS	DepMap CRISPR Gene Dependency	1.0	2.18139
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44564
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4419
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ONS-76	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0807
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.69849
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4534
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.970082
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03167
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	3.67662
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90476
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8449
LPS510	DepMap CRISPR Gene Dependency	1.0	2.16594
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.71646
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.45678
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54102
WM983B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30251
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8166-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14272
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.973427
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60516
Umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930053
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1665
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.678743
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.47413
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11454
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41133
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848548
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86333
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939621
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02514
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100348_TCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51041
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.87738
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.98274
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97411
496100424_FWM_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.42032
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.37883
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62011
odorant binding	GO Molecular Function Annotations 2015	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90037
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.3944
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08132
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74787
Congenital hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.22696
KPL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32113
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28096
LMSU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.037
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98896
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.996477
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06249
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.7767
CHSA0011	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.3279
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12959
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42458
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
RDES	CCLE Cell Line Gene CNV Profiles	1.0	1.4143
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875322
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4374
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.45021
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGM2_KD_GSE23702_715_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5026
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0351
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.37133
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36649
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.824519
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861736
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26287
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96913
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99978
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.452
single-organism process	GO Biological Process Annotations 2015	1.0	null
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.959694
SUM149PT	DepMap CRISPR Gene Dependency	1.0	2.45924
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840862
HS729	DepMap CRISPR Gene Dependency	1.0	2.1336
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18244
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05857
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.39444
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848548
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930693
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG231	DepMap CRISPR Gene Dependency	1.0	3.83524
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1352
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5899
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3307
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.805639
ST486	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.21418
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11826
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37773
SIRT1_KO_GDS3666_295_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09779
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27097
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15833
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58974
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864452
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.88314
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.71104
EM2	DepMap CRISPR Gene Dependency	1.0	2.58043
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	2.80282
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26688
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2842
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RL	DepMap CRISPR Gene Dependency	1.0	2.7627
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20083
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1288
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40111
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.693209
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33898
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58291
LP1	DepMap CRISPR Gene Dependency	1.0	5.13928
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.14775
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.86198
MFE319	DepMap CRISPR Gene Dependency	1.0	4.57191
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.65119
496100588_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07085
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07058
TE6	DepMap CRISPR Gene Dependency	1.0	5.66005
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90603
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.79177
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05557
TE11	CCLE Cell Line Gene CNV Profiles	1.0	1.76328
PBX1	ChEA Transcription Factor Targets	1.0	null
SP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0552
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994694
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1765
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40907
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986255
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.47523
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58831
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28144
receptor activity	GO Molecular Function Annotations 2015	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35066
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2289
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.77625
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8532
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944305
EFO27	DepMap CRISPR Gene Dependency	1.0	2.4138
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846678
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.52043
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891201
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64844
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.024
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02254
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944114
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863774
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1295
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.306
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
NLRP1 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8718
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2288
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6413
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.39221
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991351
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4603
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02687
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02557
neurological system process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_01_337	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6572
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SNU620	DepMap CRISPR Gene Dependency	1.0	3.40685
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.744
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.717453
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935616
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08821
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21989
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49728
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BIN67	DepMap CRISPR Gene Dependency	1.0	3.32788
MM370	DepMap CRISPR Gene Dependency	1.0	2.73821
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8695
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5280-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.618
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.681
PACADD161	DepMap CRISPR Gene Dependency	1.0	2.99586
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.80233
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50577
CORL47	DepMap CRISPR Gene Dependency	1.0	2.50736
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.988229
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85093
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0905
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4711
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9385
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72489
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86333
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.31
KYO1	DepMap CRISPR Gene Dependency	1.0	6.03553
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84965
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5206
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5181
Brain Lower Grade Glioma_LGG_TCGA-HT-7879-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
LS1034	DepMap CRISPR Gene Dependency	1.0	2.08994
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4987
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02557
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55927
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0089
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.374
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51292
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_2day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7039
SNU449	DepMap CRISPR Gene Dependency	1.0	2.24282
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21989
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.301
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19327
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.886635
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42762
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.35543
HSC3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44267
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.669767
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.78696
EGI1	DepMap CRISPR Gene Dependency	1.0	2.34758
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18046
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930053
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891193
SUM229PE	DepMap CRISPR Gene Dependency	1.0	2.01183
cellular_component	GO Cellular Component Annotations 2015	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0983
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45296
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50633
TE5	CCLE Cell Line Gene CNV Profiles	1.0	2.62497
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.47193
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29522