association	dataset	threshold value	standardized value
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833046
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874928
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4655
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07552
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70642
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.60222
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02171
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98343
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19832
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5194
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09557
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9589
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.74954
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	1.44916
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4528
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56712
COL18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05109
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF268	DepMap CRISPR Gene Dependency	1.0	3.0518
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09557
CMK115	DepMap CRISPR Gene Dependency	1.0	4.54197
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34908
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.55817
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878641
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6309
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78219
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7037
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PC14	CCLE Cell Line Gene CNV Profiles	1.0	1.40803
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874928
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.82739
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ski complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.403
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.758276
Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Perturb_6724_KD_PAF1_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.30208
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79638
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1149
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.0044
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6518
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.95148
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.79137
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1459
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04215
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.77618
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4107
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2605
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70145
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862397
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57155
GSU	CCLE Cell Line Gene CNV Profiles	1.0	2.01177
LS-123	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0375
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RANBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57626
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37965
ZNF99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70835
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875997
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832473
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.527
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vagina	GTEx Tissue Gene Expression Profiles	1.0	0.891121
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.087
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10262
TE5	DepMap CRISPR Gene Dependency	1.0	6.46453
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875997
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17179
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45196
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90513
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.365
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.87565
biological_process	GO Biological Process Annotations 2015	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.40084
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PECAPJ41CLONED2	DepMap CRISPR Gene Dependency	1.0	2.61081
sensory perception	GO Biological Process Annotations 2015	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02403
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.07966
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17068
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	2.94692
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC461	DepMap CRISPR Gene Dependency	1.0	2.70909
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO27	DepMap CRISPR Gene Dependency	1.0	2.94519
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3512
Congenital myasthenic syndrome 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.211
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60562
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18462
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6662
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10384
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.406
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34435
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3155
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YKG1	DepMap CRISPR Gene Dependency	1.0	5.5598
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7013
Signal Transduction	Reactome Pathways 2014	1.0	null
SW1783	CCLE Cell Line Gene CNV Profiles	1.0	1.37462
PDK1_knockout_265_GSE42187	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.38629
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6865
NB7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832473
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5075-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.775146
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947306
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7329
DOK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93928
CTCF	ENCODE Transcription Factor Targets	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.61931
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.11109
TE10	DepMap CRISPR Gene Dependency	1.0	5.00129
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0228
ICC2	DepMap CRISPR Gene Dependency	1.0	3.26561
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57938
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24776
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0577
JUND	ENCODE Transcription Factor Targets	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2207
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22805
OCIMY7	DepMap CRISPR Gene Dependency	1.0	5.23743
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
neurological system process	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49265
SNU475	DepMap CRISPR Gene Dependency	1.0	4.17996
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2684
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.69424
Sarcoma_SARC_TCGA-DX-A23Y-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_5_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2802
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7009
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	3.64159
KYSE520	DepMap CRISPR Gene Dependency	1.0	3.30947
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
TP53BP1_KD_GSE54268_669_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7711
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05428
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01352
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19478
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2746
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48433
NCI-H2135	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
SHP77	DepMap CRISPR Gene Dependency	1.0	8.66087
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35491
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.934
TXNDC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42981
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986464
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
odorant binding	GO Molecular Function Annotations 2015	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14763
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0276
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67791
GSE182680,GSE182683_10_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78909
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.86
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59708
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12516
Mesothelioma_MESO_TCGA-MQ-A4LV-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
9505BIK	DepMap CRISPR Gene Dependency	1.0	4.44345
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.395
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9061
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18462
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0375
SUDHL4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45795
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22875
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02171
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875997
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6232
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8542
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47093
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862397
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
PECAPJ15	DepMap CRISPR Gene Dependency	1.0	3.29347
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.74924
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950474
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6388
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.75145
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.39208
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32441
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0225
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.6803
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMBIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19775
MDAMB435S	CCLE Cell Line Gene CNV Profiles	1.0	1.40149
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950474
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3536
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10384
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1163
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.764862
OCUM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GAMG	DepMap CRISPR Gene Dependency	1.0	5.47075
NCIH2171	CCLE Cell Line Gene CNV Profiles	1.0	1.53518
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00116
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0375
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923675
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878641
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06264
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0902
TT	CCLE Cell Line Gene CNV Profiles	1.0	2.09865
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874928
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5654
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0509
Olfactory transduction	KEGG Pathways 2026	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9587
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86947
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32441
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
HUH7	DepMap CRISPR Gene Dependency	1.0	2.91772
signal transduction	GO Biological Process Annotations 2015	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6139
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS-Cov_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.63188
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	8.50616
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60758
CXCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12063
KYSE450	CCLE Cell Line Gene CNV Profiles	1.0	1.47172
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9249
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36121
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.0107
496100633_TCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.07923
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0963
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5717
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.852641
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25335
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.51377
KMRC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56391
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.798
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2598
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6837
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
NMCG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41331
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-DX-A3U6-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35931
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0276
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.0044
single-organism process	GO Biological Process Annotations 2015	1.0	null
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.76883
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0855
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3256
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9313
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9246
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2755
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1568	CCLE Cell Line Gene CNV Profiles	-1.0	-2.86881
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4309
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0186
D283MED	DepMap CRISPR Gene Dependency	1.0	2.04933
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68885
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4973-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9167
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6016
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.149
Signaling by GPCR	Reactome Pathways 2014	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39656
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5359
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8389
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68862
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35455
SOX2_Deficiency_GDS4853_319_human_AZ-521 gastric cancer (GC) cell line - 8 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05428
H2795	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hypotonia-cystinuria syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0905
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14763
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3105
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8161
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-1.0044
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4791
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16154
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2704
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29869
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9119
SF126	DepMap CRISPR Gene Dependency	1.0	6.91913
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02171
U2904	DepMap CRISPR Gene Dependency	1.0	3.26394
SF172	CCLE Cell Line Gene CNV Profiles	1.0	2.78503
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944886
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8616
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
SKPNDW	DepMap CRISPR Gene Dependency	1.0	5.13769
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49265
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923675
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7013
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5296
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	2.72507
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22772
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51455
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8756
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989345
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2038
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1167
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34908
EW-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.4357
PANC-08-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22835
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22473
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45017
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3506
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924393
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2592
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51159
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE21	DepMap CRISPR Gene Dependency	1.0	4.79143
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1515
KMS20	DepMap CRISPR Gene Dependency	1.0	2.71265
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43781
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40079
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3372
MM426	DepMap CRISPR Gene Dependency	1.0	2.79918
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7875
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3209
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5427
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.108
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.347
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9693
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.49969
CA46	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate-myeloid cell	Tabula Sapiens Gene-Cell Associations	1.0	2.41385
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24014
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832473
RCOR1	ChEA Transcription Factor Targets	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.28952
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11508
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6606
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.859109
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10384
SG231	DepMap CRISPR Gene Dependency	1.0	4.50603
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4795
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MON	DepMap CRISPR Gene Dependency	1.0	3.01191
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944886
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13999
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59946
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6181
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05932
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10298
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.082
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.71598
PAX5_OE_GDS4978_547_human_L428	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.819
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.847
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2651
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
CAL62	CCLE Cell Line Gene CNV Profiles	1.0	1.77507
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6981
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57108
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8434
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CASKI	DepMap CRISPR Gene Dependency	1.0	3.05643
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32441
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.5119
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70288
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07568
CHLA15	DepMap CRISPR Gene Dependency	1.0	2.91998
HEC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.63568
SF295	DepMap CRISPR Gene Dependency	1.0	2.01335
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831722
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33849
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67776
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37155
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10262
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832473
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3451
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27546
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6869
BRAF_drug inhibition_GSE42872_368_human_A375	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923675
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32751
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	2.32805
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878641
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47093
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923675
A375SKINCJ2	DepMap CRISPR Gene Dependency	1.0	3.73762
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
SF126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89891
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2478
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13294
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832473
SW403	DepMap CRISPR Gene Dependency	1.0	3.27524
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.05
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.766652
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40079
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874928
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45017
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.0044
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36121
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HO1U1	DepMap CRISPR Gene Dependency	1.0	3.38315
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.826
SLR24	DepMap CRISPR Gene Dependency	1.0	2.04694
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
LN340	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48136
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.936402
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7109
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.758212
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.676415
GSE239844_7_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30507
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2988
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.177
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04314
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDUFAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63265
Lung adenocarcinoma_LUAD_TCGA-05-4382-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0748
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2527
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878641
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862397
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82192
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0453
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.6828
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932596
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2351
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06512
Uncontrolled blood pressure in combination therapy (beta blocker and thiazide diuretic)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.74212