association	dataset	threshold value	standardized value
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37556
BRD-K93483334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10516
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32589
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.51655
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862243
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1693
NCIH1838	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Pallidum, ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5829
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03874
BRD-K85200795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09567
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3717
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950852
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3011
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2212
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29927
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45184
BRD-K36460068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25405
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08352
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60002
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49516
binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48245
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23755
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.725
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.37022
ICC4	DepMap CRISPR Gene Dependency	1.0	2.81406
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18339
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70975
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5009
KU1919	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42082
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47652
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2909
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76435
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K95459450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03654
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040641
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61025
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13371
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71266
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74096348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2892
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.59808
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70572
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NB17	GDSC Cell Line Gene Expression Profiles	1.0	1.62406
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57893
CRCGN011_HEPG2_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06335
periventricular stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79845
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92282
BRD-K98704738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36368
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5277
BRD-K37763427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06343
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.552
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5757
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77401804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.318
sensory perception	GO Biological Process Annotations 2015	1.0	null
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23249
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3897
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.18514
SOX9_01_309	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.75221
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4461
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.86041
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51763
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6355
TCF4	ChEA Transcription Factor Targets	1.0	null
chrysophanic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7973
Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3835
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89512
CAL-51	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64929
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51742
Specific language impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
BRD-K52049165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35256
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1456
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12262
IRF8-21731497-J774-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38306
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.13542
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3265
BRD-K27147269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73395
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AMO1	DepMap CRISPR Gene Dependency	1.0	2.48423
BRD-K54862370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00508
all	GWASdb SNP-Phenotype Associations	1.0	0.029377
dorsolateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27972
PMC7994904-42003_2021_1929_MOESM3_ESM.xlsx-Supplement1-SI12-TOP_100-CTCFL_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01473
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14541
BRD-K17886576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19165
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38899
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3707
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45968
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857954
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80233876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03746
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1362
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89512
BRD-K75626008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13037
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56371
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K12866026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13602
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0094
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.64125
BRD-K05125666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12286
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65235
BRD-K79730625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02736
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4806
JAR	DepMap CRISPR Gene Dependency	1.0	2.93065
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3175
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01489
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4298
BRD-K83916197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4342
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12877
Inferior colliculus, external nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27047
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6068
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936796
CDX2_01_357	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.29505
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20036
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9676
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.643
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77766
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34678
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831822
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.5029
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8259
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02157
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39699
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.12127
BRD-K49490091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61378
BRD-K71538933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7355
BRD-K37721603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65488
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26586
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.94429
BRD-K82130737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24499
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0496
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938687
BRD-K24020784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5376
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883355
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61451
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2711
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15929
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88685
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42583
NP8	DepMap CRISPR Gene Dependency	1.0	4.84654
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2678
BRD-K77950699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33038
BRD-K28982281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98907
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.102
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4859
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985909
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.94105
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847054
BRD-K68055156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46004
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.82334
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45303
BRD-K69074358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76485
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05512
BRD-K39773004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25113
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35589
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29617
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.953
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.17231
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0874
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2392
BRD-K97666659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32246
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0496
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Unnamed_6_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47143916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30224
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2571
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1083
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.02
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29471
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36605
SOX9_01_308	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.75221
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90993
periventricular stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12498
liminal part of r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10803
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
HGC27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57209
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04034
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K24529791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6888
BRD-K10048365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37565
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57265
mantle zone of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3166
r2 part of the ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14981
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26765362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19546
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952268
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0033
BRD-K37055068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18927
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3601
BRD-K54657536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26712
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14445
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11459
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6632
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7605
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.09502
BHT-101	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64197
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09176
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852027
CRCGN016_MCF10A.WT.HP_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13821
BRD-K78837609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65399
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.38149
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95422
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885201
BRD-K50216418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02611
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92199
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23407
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13925
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K20435953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03011
NCIN87	DepMap CRISPR Gene Dependency	1.0	3.78716
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70312
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC_INHIBITION - trichostatin A_GDS2452_709_human_Endothelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K22718400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4171
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42055
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06767
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00254
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0732
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9253
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09411
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8599
subpretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18766
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01241
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.2522
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.7093
BRD-K89832379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28707
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.835
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1405
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89015
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5263
BRD-A64774838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08343
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36275
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862243
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34686
BRD-K48436333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32811
BRD-K37989903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35824
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13396
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7476
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68876
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.35867
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4719
Hepatoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5016
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852027
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38196
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11459
BRD-K93693615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19525
HCC1419	DepMap CRISPR Gene Dependency	1.0	6.98312
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3698
BRD-K48050202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07081
BRD-K30171122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23074
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862816
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80709
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCV JFH-1_18Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.46412
BRD-K80469338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32919
myc_17159920_cancer_cell_lines_lof_human_gpl570_gds2526	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.971311
BRD-K82909038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17485
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06553
BRD-K39597125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09862
system process	GO Biological Process Annotations 2015	1.0	null
D-283MED	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50319
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4148
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040443
BRD-K04877446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12323
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0768
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13396
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03765
ZR-75-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
BRD-K98427581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50527
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5856
GSE111035,GSE111040_10_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.893308
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4679
BRD-K57497543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26433
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88605
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39632
BRD-A73618687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00942
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1319
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868501
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.3773
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6246
EFE184	CCLE Cell Line Gene Expression Profiles	1.0	1.61255
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20701
BRD-A85028244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06097
NCIH28	DepMap CRISPR Gene Dependency	1.0	3.06859
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86596
BRD-K02602127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69872
BRD-K29711480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5545
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	1.89893
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5677
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.20117
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2992
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10678
BRD-K83946740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44767
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79547691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38595
BRD-K67609710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04123
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96649
ACF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
p1Lim part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79845
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4298
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57157
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	1.45579
POU3F2	ChEA Transcription Factor Targets	1.0	null
BRD-K96023136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32267
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919482
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5505
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13523
BRD-K03599766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11623
IRF8	ChEA Transcription Factor Targets	1.0	null
SF767	DepMap CRISPR Gene Dependency	1.0	6.04658
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3008
BRD-K32960568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29933
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1155
BRD-K01152687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27533
BRD-K70876639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22875
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.053
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5144
intermediate stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50093
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6778
CRCGN012_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.168
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.08082
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K94306568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71352
CRCGN014_HEPG2_24H:N08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29733
SNU387	DepMap CRISPR Gene Dependency	1.0	2.22135
BRD-K36544054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07967
BRD-K80413110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05947
GSE189219_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40766
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7408
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52867
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4925
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.86095
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
breast	GTEx Tissue Gene Expression Profiles	1.0	0.876865
BRD-K78098006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29619
ventral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77846
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6061
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15929
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01894
BRD-K37588779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45097
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47069
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2102
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1483
intermediate stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14981
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51662
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18371
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5387
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87103
HCC1195	CCLE Cell Line Gene Expression Profiles	1.0	1.70667
PL4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2327
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0099
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06197
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1137
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00235
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	1.01298
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27738
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63074
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.673
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852027
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.724
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20634
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2842
Dyscalculia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1633
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7852
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	2.50177
SNU475	CCLE Cell Line Gene CNV Profiles	1.0	2.29254
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30716
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44766
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933647
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3104
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4859
DAOY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2815
BRD-K73730918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02885
BRD-K80443236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2813
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.104
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.62519
BRD-K35156336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01857
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49253
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6586
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06994
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10182
BRD-K96485138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67643
KP-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU1040	CCLE Cell Line Gene Expression Profiles	1.0	1.42691
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.47962
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.7775
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46376
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4474
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7031
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H378	GDSC Cell Line Gene Expression Profiles	1.0	2.64393
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.0765
BRD-K39863565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80755
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03874
BRD-K34701680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58276
BRD-K82105167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69387
LI7	DepMap CRISPR Gene Dependency	1.0	4.86784
TT	CCLE Cell Line Gene CNV Profiles	1.0	2.40661
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2296
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35595
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17188
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86714
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4769
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64211
BRD-K76114475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43275
BRD-K96807219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16375
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.926198
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K06428422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48631
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47808
BRD-K21125528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4101
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16114
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0824
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35301
EPLC272H	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31728
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947503
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15522
BRD-K11117868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64121
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34196
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11873
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8267
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27767
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61139
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0666
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6463
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919988
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9092
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59714
KYSE-220	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01074
NLRP1 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
BRD-K17749779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26477
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6985
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9647
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65421
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70319
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5066
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90482
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40314
BRD-K58286708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25984
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97712
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0175
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4409
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861304
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2383
CRCGN012_HEPG2_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23036
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39386
SKLMS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78187
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111035,GSE111040_10_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
NUGC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65141
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
BRD-K28795679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54702
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6209
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865728
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3855
BRD-K81031146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16687
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH157DM	DepMap CRISPR Gene Dependency	1.0	3.29515
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0814
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.32834
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.6631
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1186
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09193
TEK_knockdown_122_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.85274
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.39
BRD-K28983467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.009
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_3_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02157
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.3033
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.98324
tetraethylenepentamine-498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7852
WM88	CCLE Cell Line Gene Expression Profiles	1.0	1.41232
253J	CCLE Cell Line Gene Expression Profiles	1.0	2.50644
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.17369
BRD-K44537081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23727
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40991
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6359
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5166
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894961
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10803
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5041
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.70052
BRD-K11630986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77651
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98971
BRD-K61271364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78987
CLDN1_OE_GDS3510_393_human_CL1-5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OC315	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10383
BRD-K13226207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11623
BRD-K96745500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31871
BRD-K27723822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1788
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0163
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848686
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950852
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21717
BRD-K68438316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12481
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	2.77824
BRD-K20030272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91271
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33581
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06869
BRD-K58779593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4614
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040726
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2646
BRD-K81457218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12396
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45717
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-01A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.74542
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919988
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2103
BRD-K55895855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62444
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5176
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37528
BRD-K61494613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05358
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26258
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07119
BRD-K76966915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43995
BRD-K91944762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04309
ornidazole-5483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11136
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5246
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
EHEB	GDSC Cell Line Gene Expression Profiles	1.0	1.52559
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CCFSTTG1	DepMap CRISPR Gene Dependency	1.0	2.34416
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62941
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862029
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43099
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12133
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852027
BRD-K92524632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62034
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3023
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0239
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.36359
receptor activity	GO Molecular Function Annotations 2015	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3995
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2108
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1725
MAFK	ENCODE Transcription Factor Targets	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845544
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SJSA1	DepMap CRISPR Gene Dependency	1.0	2.80963
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.94534
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82587
BRD-K02053819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28593
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7634
intermediate stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33534
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6002
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6041
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55505
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.88158
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.17343
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3852
PMC6011013__F5	PFOCR Pathway Figure Associations 2024	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4105
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25901
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.27535
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.710066
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25418
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5229
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33162
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20152
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4426
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31214
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44024
HMC18	CCLE Cell Line Gene Expression Profiles	1.0	2.22809
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16187
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01842
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899729
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917998
JHH6	DepMap CRISPR Gene Dependency	1.0	2.26662
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K38907993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4245
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893833
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73743
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03693
CRCGN015_MCF10A.WT.HP_24H:B04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06829
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6907
NCCMPNST2C1	DepMap CRISPR Gene Dependency	1.0	3.40079
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34677
odorant binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69843
CRCGN008_HEPG2_24H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0535
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02105
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964706
RD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48576
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44024
16513838-Table3	GeneSigDB Published Gene Signatures	1.0	null
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5671
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07119
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4241
786	BioGPS Cell Line Gene Expression Profiles	1.0	1.30038
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35165
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30643
BRD-K45904306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2381
BRD-K46074482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03243
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827606
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23943
BRD-K28448768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55655
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897391
A-Netherlands-602-2009(H1N1)_30Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.1313
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34109
BRD-K22599787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59168
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978376
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7864
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18101567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30291
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
CRCGN012_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0158
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29156
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040341
VM-CUB-1	GDSC Cell Line Gene Expression Profiles	1.0	1.431
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1091
BRD-K98535230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08003
HDQ-P1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7315
BRD-A91891312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76868
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23314
BRD-K27028848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17621
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8473
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25365
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34934
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13383
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.264
BRD-K26200435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07799
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7574
BRD-K87878529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02713
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	1.82689
GSE146865,GSE146866_1_v_3_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.293
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.28161
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.04519
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67716105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04844
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32485
BRD-K10459843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20744
NCI-H1838	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.36169
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2748
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.20853
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40845
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9374
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-K64356525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00536
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96235
MET_knockout_263_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-3.09114
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11141
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.3885
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1089
Beckwith-Wiedemann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21148
IPC298	DepMap CRISPR Gene Dependency	1.0	7.02158
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
BRD-K74754874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2784
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0826
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68422
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22528
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13337
biological regulation	GO Biological Process Annotations 2015	1.0	null
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06713
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37063
clofibrate-444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K41993678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86549
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2316
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.075201
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76932
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02159
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3156
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.90396
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4937
IRAK1_knockdown_115_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.8155
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6281
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06648
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.98952
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27477
BRD-K82637883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29568
CRCGN016_MCF10A.TP53.M_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37263
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00754
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8903
BRD-K77483143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41745
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K00976973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28369
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K99302735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84108
BRD-K84128738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0753
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07893
BRD-K90092568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35131
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74977
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4187
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985909
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	1.6124
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72267
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.880076
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	207.072
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26258
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.48281
BRD-K63754039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99693
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33236
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21515
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18043
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5805
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.48281
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3183
CRCGN014_HEPG2_3H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23417
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94401439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18405
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5068
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.74117
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4486
LM-1685-612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59936
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.769338
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0688
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7096
BRD-K63919349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35095
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69548
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46412
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1512
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825324
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33465
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	1.05353
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24718
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.28174
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.901567
BRD-K08658757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12403
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27281
BRD-K25484053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20499
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50152
BRD-K19501975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65598
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39733
BRD-K37942718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03912
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.931649
BRD-K74300740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46436
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78338
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850933
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.03521
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4708
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40663
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.187
OE21	CCLE Cell Line Gene CNV Profiles	1.0	1.6467
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6423
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97085
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39191
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90925
P-TEFb complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
HCA1	DepMap CRISPR Gene Dependency	1.0	2.25399
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08189
IOSE80	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.25761
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51179
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24575
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20617
CRCGN017_MCF10A.WT.HP_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2596
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23522
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07814
BRD-K76588081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47759
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22269
arachidonic acid-441	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1017
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95422
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24575
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92124
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.14458
RCOR1	ChEA Transcription Factor Targets	1.0	null
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914802
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843634
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03326
BRD-K03562091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13418
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.0841
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4297
ventral pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39699
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
mantle zone of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77846
BRD-K26850845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20141
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27448
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1527
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09265
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76451
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04373
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37524
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87307
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
16160012-Table1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K24532125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45279
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2791
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01225
BRD-K80766355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42883
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03864
BRD-K54934070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.424
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3553
EWS502	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52516
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9444
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5074
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7325
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46663
BRD-K16943897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23874
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0477
p3 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54039
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.30038
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3149
BRD-K61022988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40746
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9882
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.086
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62281
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9666
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K79521948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32831
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8489
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_UP_2_5-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE510	CCLE Cell Line Gene Expression Profiles	1.0	1.41043
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95299
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.41185
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19182
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.62805
SNU1033	CCLE Cell Line Gene CNV Profiles	1.0	1.73905
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2198
mantle zone of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10803
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11877
BRD-K08311368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01276
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9165
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11877
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6043
UHO1	DepMap CRISPR Gene Dependency	1.0	2.60642
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8943
CRCGN014_HEPG2_3H:A05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02682
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17865
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34525
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49184
BRD-K81804676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10455
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30728
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0201
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13615
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_A549_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23489
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0923
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.3194
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01074
BRD-K92022897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21014
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.939343
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4404
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30765
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02481
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57126
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03824
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0465
BRD-K17602350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07566
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47152
PMC11554977-40199_2024_523_MOESM2_ESM.xlsx-Sheet1-Supplement_2_Metformin_Drug_Sensitivity_and_Damaging_Mutation_by_using_PRISM_Repurposing_Primary_Screen_and_Damaging_Mutation_in_DepMap_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86953192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25797
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.37636
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6574
BRD-K79829201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53383
Striatum ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06079
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23569
YH-13	GDSC Cell Line Gene Expression Profiles	1.0	1.50014
BRD-K81501934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.835
periventricular stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27972
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.691
Arterial calcification of infancy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5383
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16187
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33221810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04811
PD-128907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19991
BRD-K64039518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72595
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72363
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13396
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03948
BRD-K11493601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15054
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25365
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.805
BRD-K48756106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39208
BRD-K74095559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22824
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.67942
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54844
BRD-K26161397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.093
LOX-1_OE_GDS4262_433_human_HAECT - aortic endothelial cell line - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30959
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9469
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03803
BRD-K50240676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2948
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
BRD-K01667746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99008
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9709
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21227
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.842604
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.78781
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0062
SG231	DepMap CRISPR Gene Dependency	1.0	2.37517
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.77178
BRD-K69375224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37446
BRD-K32084247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71925
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K90882192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31501
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77846
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8034
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.880731
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4087
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.543
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6106
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.6585
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.48346
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63557
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41004
BRD-K84158675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13007
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45259
BRD-K39824708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49115
BRD-K13968264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10416
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1793
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6579
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.7597
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8488
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.94045
NCI-H2085	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8707
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47457
Sensory Perception	Reactome Pathways 2024	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.928943
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22551
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.53022
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01667
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5975
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87188
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20617
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.3614
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.3368
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54031
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.49709
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01382
BRD-K78397696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01537
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.31705
BRD-K69740275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55791
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1084
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9797
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0588
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE239578_0_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50085
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05608
BRD-K38189757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39225
reticular formation of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12729
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3352-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K74987024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20019
BRD-K32988853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03757
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4652
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62524
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
BRD-K31952722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00349
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1912
BRD-K03383196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13132
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2711
MFE-280	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50733
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54481
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34572
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9924
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7239
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00901
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1022
CRCGN014_HEPG2_3H:C14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10968
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986968
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.996386
BRD-K52310606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02014
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14712
Signal Transduction	Reactome Pathways 2014	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029408
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8569
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23925
BRD-A34826857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25698
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27221
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.86026
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
16513838-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.4844
low-density lipoprotein receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.31371
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0496
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_CUTOFF_2_5_TOTAL-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.81235
BRD-A62787624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19769
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83877780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64189
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23249
artery disease	GWASdb SNP-Disease Associations	1.0	0.148837
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-3.23679
BRD-K02078984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9589
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23346
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26718
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.48246
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957967
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4704
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31782
BRD-K92607052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34833
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91328
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03012
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.50626
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5922
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	113.85
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870524
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1612
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62896
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2959
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.58135
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28016
CRCGN017_MCF10A.TP53.M_24H:H11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00297
BRD-K50851442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11457
496100513_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	15.6448
BRD-K69922285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03565
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59822
GSE191138_3_v_4_fmo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04083
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.386
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25844
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	1.21605
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62939
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31715
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23522
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K84060528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29624
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33539
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31462
BRD-K42828928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33667
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0482
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3012
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6194
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.392629
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3767
BRD-K67874412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22804
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2873
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2134
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8419
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.73831
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	1.89666
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10803
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51394
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919988
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26973
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60047
S117	DepMap CRISPR Gene Dependency	1.0	2.79531
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67601
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31255
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8707
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91521
OCIAML3	DepMap CRISPR Gene Dependency	1.0	3.75749
BRD-K96979108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78097
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00551
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3751
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.244
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37555
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23247
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41246
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4303
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.4928
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	1.5999
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.6923
BRD-K85513726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09176
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44023
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2411
Mesenchymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07902
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38563
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83807
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15486
MZ in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1506
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.54235
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43599
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9228
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8602
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78174
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84198
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3931
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02047
BRD-K10481024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03915
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862243
BRD-K15047839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82643
BRD-K11016405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23605
membrane	GO Cellular Component Annotations 2015	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.4749
BRD-K61929684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56147
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.895
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.19031
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50775
layer 5 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67322
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01654
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892844
BRD-K07278815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28642
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53025
indometacin-262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.705035
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52808
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18182
BRD-K83775558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07371
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22163
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72163
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K14166654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01433
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.108021
BRD-K93543569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26406
SOX4_01_260	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59711
BRD-K96637326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3319
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41004
BRD-K20714346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4684
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26518
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68257
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30728
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0336
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25964
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040984
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.11168
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.47925
signal transduction	GO Biological Process Annotations 2015	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11918
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-LGG_MYB_L1_deletions-Unnamed_2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2739
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04589
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26586
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4003
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40119
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889306
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08455
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3326
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.895317
BRD-A12894472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04729
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.47268
hypertension	GWASdb SNP-Disease Associations	1.0	1.15964
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63345
KMRC3	DepMap CRISPR Gene Dependency	1.0	2.9733
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4654
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59591
A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.00991
BRD-K82082713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34915
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.663503
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61087
LN18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77048
Olfactory transduction	KEGG Pathways 2026	1.0	null
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5725
PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SKMEL31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35337
CLDN1_OE_GDS3510_31_human_CL1-5 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883374
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.26811
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.43715
BRD-K71296038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30251
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07092
BRD-K05060234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73068
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827606
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93522
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826357
BRD-K62536891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16089
BRD-A57457448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7347
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5199
NCIH446	DepMap CRISPR Gene Dependency	1.0	2.88425
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1011
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17765
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889306
BRD-K80782159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04434
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5735
BRD-K04731905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07948
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1907
CAKI2	DepMap CRISPR Gene Dependency	1.0	5.05779
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1268
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18371
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DNAJC2	ChEA Transcription Factor Targets	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38502
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.6189
BRD-A95480808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53677
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26526
BRD-K45683404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04091
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2137
BRD-K10160311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24353
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.910889
BRD-K76461283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47501
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56897
BRD-K89820077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46203
BRD-M01343043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55379
BRD-K06152379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44606
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96346
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9006
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32497
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.24711
CHLA57	DepMap CRISPR Gene Dependency	1.0	5.21226
BRD-K91241684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07207
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62879
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.8515
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF126	DepMap CRISPR Gene Dependency	1.0	4.75297
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4562
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982146
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.68759
SKRC20	DepMap CRISPR Gene Dependency	1.0	8.58535
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993345
BRD-K17384993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12058
SNU423	DepMap CRISPR Gene Dependency	1.0	3.70753
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1436
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28086
BRD-K32079609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16426
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96168
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4938
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4645
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.0859
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
MELHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34355
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.3495
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51805
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15089
BRD-K50171760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00043
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5447
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3109
RKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912937
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28072
BRD-K12260863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23517
disease	GWASdb SNP-Disease Associations	1.0	0.025891
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79155
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989091
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.34385
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.657267
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87984
Placenta	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38273
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12133
GSE189219_0_v_1_atoh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4989
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1912
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52681
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6397
BRD-K99824630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35465
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4226
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62053
KM12	GDSC Cell Line Gene Expression Profiles	1.0	1.43459
ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.726599
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17644
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0125
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05642
KPL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47265
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52505
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3164
BRD-K25016708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33288
YD38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.47761
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29413
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.846684
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90736603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24367
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08411
BRD-K32722078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43194
Ebolavirus(EBOV)_5day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.11139
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38429
BRD-A24714998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47895
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4884
intermediate stratum of p2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2711
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10768
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14155
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.78106
HT1376	DepMap CRISPR Gene Dependency	1.0	4.40898
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	1.49805
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85307083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41938
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.46528
BRD-K00083518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44576
BRD-K84688359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67627
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.70125
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46405
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8371
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4433
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14981
mRNA_TCEA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.314
prerubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44024
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09712
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5979
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.67914
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.019
BRD-K09919985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09564
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
ventral juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33534
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.5784
BRD-K27347421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07655
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990699
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4605
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01643633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13553
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37845
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1992
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08097
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14788
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.938055
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.99944
BRD-K98510376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69927
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8448
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5672
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8897
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76509
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82115725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14333
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
p1 part of the pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4884
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9347
BRD-K57639176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22618
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.81347
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12843
BRD-K10325583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0839
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.574
BRD-K67632894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54844
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85531
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MD-01A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-M1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199356
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26586
BRD-K43624274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3823
BRD-K89232006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00043
BRD-K61316494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39817
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35214
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915015
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
speech-language disorder-1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
COLO818	CCLE Cell Line Gene Expression Profiles	1.0	1.44286
PMC6011013__F4	PFOCR Pathway Figure Associations 2024	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4249
CRCGN017_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29589
BRD-K18346873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51679
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5139
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05036
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.029628
liminal part of r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3166
BRD-K24496049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22248
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0094
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31296
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85348
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23289
BRD-K39176069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26874
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01996
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06811
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0224
PRKCA_knockdown_118_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73575
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.962324
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4975
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13396
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7038
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7432
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.90681
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5527
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62485
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77846
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23088
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1064
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	2.00524
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1724
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17126
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.8384
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62513
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42098
intermediate stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12729
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.930741
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852027
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4253
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.53101
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3818
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041269
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6071
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09923
BRD-K97985992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20659
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08411
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.90555
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08411
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23522
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852027
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05532
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2532
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885201
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.1936
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05251
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60044
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89755
BRD-K00853706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14397
NANOG	ChEA Transcription Factor Targets	1.0	null
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K38131403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56896
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16431
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.474
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.98335
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990699
IKZF1_01_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59912
BRD-K75649446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00576
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6124
MELHO	DepMap CRISPR Gene Dependency	1.0	2.12315
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862816
BRD-K37029442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00414
OCIM2	DepMap CRISPR Gene Dependency	1.0	2.63957
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.0119
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5854
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72907
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06947
BRD-K21176717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11398
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54321
BRD-K03205303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01403
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.868045
BRD-K07526417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2395
Superior colliculus, motor related, intermediate gray layer, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14135
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03923
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0703
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0117
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05838
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7156
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.73068
BRD-K68087668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01493
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01265
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1182
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850933
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58679
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69241192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27951
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5462
639-V	GDSC Cell Line Gene Expression Profiles	-1.0	-2.20315
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.31755
BRD-K58445641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.687
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839324
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63027
BRD-K18428988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28541
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.672
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00448
BRD-K31526203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24099
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28174
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42835
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24854
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE11	CCLE Cell Line Gene CNV Profiles	1.0	1.38519
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4571
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18237
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23522
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17188
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82018
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
EW-22	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47882
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.0927
BRD-K21143905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62998
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34521
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2625
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4758
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50352
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0453
BRD-K90151990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13542
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44394
CRCGN014_HEPG2_3H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37906
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.918
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61345
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09325
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38735
BRD-K64135153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11367
BRD-K07160568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1849
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49705
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11503
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.8821
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0664
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82587
BRD-K62833799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0649
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16227
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9003
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.895
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990699
BRD-K77241556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90215
BRD-K88542817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05485
BRD-A57285050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1686
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0348
BRD-K98016463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95876
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07092
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20364
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.54395
BRD-K45592944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05426
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2257
BRD-K65427501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16658
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32595
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3151
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61003
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.38866
BRD-K26399271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46518
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23135
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8912
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5322
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9034
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3177
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.91297
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LIVF001-002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68924
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71818
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0748
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55797
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8339
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28517
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K48987279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46162
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1378
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75998
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.907966
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0257
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.44737
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3957
copper sulfate-575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K24166534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41286
BRD-K24443173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21204
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.663
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91812
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10551
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6197
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4044
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5704
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.48539
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39897
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23648
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2432
HS683	DepMap CRISPR Gene Dependency	1.0	2.01627
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45184
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.1158
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6411
MYC	ENCODE Transcription Factor Targets	1.0	null
Chromosome 2p16.1-p15 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8707
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95422
liminal part of the r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07211
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0963
BRD-K05248348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03028
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.1849
BRD-K83477969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24166
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1566
SNB75	DepMap CRISPR Gene Dependency	1.0	2.52502
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6092
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85467
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2616
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.355
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38306
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83801418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0645
BRD-K95499061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90445
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOUNH91	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45547
BRD-K59975583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04175
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05178
SUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.3668
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3897
BRD-K29898553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57378
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76297
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23583
BRD-K92239253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27831
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7884
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21183
BRD-K00789767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12218
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14366
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SNU685	DepMap CRISPR Gene Dependency	1.0	6.15113
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.37996
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.4444
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9097
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.0741
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4908
LCLC-97TM1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42882
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44105
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.79
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05552
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045064
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965567
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21206
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96133
BRD-K43192646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77414
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6078
NCIH1666	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40754
GSK3B_KD_GDS4305_183_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12712
BRD-K24502602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06937
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5578
neurological system process	GO Biological Process Annotations 2015	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4531
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22163
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1606
CTCF	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01495
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02963
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849132
BRD-K80996561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68346
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6459
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21464
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18525
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4134
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
Substantia innominata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5829
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56841
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KCIMOH1	CCLE Cell Line Gene Expression Profiles	1.0	1.49727
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35582
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36971
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35223
BL70	CCLE Cell Line Gene Expression Profiles	1.0	1.83329
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25418
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1566
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.395
18855877-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Secondary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3563
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917998
transferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047922
MFH-ino	GDSC Cell Line Gene Expression Profiles	1.0	1.75416
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1023
Signaling by GPCR	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77273085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50022
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.52
hepatoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.14348
A673	DepMap CRISPR Gene Dependency	1.0	2.14908
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68734
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05604
BRD-K08679933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44997
PMC6011013__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12509
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	1.8821
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917998
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7368
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36037
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPMI7951	CCLE Cell Line Gene Expression Profiles	1.0	2.07796
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03338
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04034
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.6603
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849679
BRD-K66708851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00173
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824634
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917408
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4624
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19527338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61498
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K44936922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05641
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02697
BRD-K95160020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64943
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
BRD-K93747042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19127
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883161
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8763
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.0002
BRD-K61821542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19878
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5166
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0208
TP53_01_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.97269
LS	DepMap CRISPR Gene Dependency	1.0	2.58085
MEL270	DepMap CRISPR Gene Dependency	1.0	3.75349
BRD-K73839552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22124
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041556
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1609
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1342
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1919
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93771
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48777
BRD-K47285393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7357
BRD-K82683018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00067
BRD-K71622214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59404
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80585
BRD-K73001304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16651
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46113
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.056693
RD	DepMap CRISPR Gene Dependency	1.0	2.14986
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59785
NCO2	DepMap CRISPR Gene Dependency	1.0	2.80984
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01939
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22457
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K44833533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15725
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11459
BRD-K92759025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11874
BRD-K31197843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28604
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3477
CRCGN015_MCF10A_48H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13198
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.01197
BRD-K23366960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44769
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE250230_1_v_3_gramd1c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1427
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3607232-mmc3.xlsx-RUNX1_targets_in_K562_and_SEM-x_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TD-01A-51R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alar part of peduncular hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3166