association	dataset	threshold value	standardized value
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.93453
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.43405
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03904
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7919
Breast Cancer_Mammary Gland Tissue_GSE1378	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.60179
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14154
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.12225
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21506
COLO824	DepMap CRISPR Gene Dependency	1.0	3.52343
SNU16	DepMap CRISPR Gene Dependency	1.0	3.65965
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26679
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39338
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5731
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05259
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Y-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17465
TE5	CCLE Cell Line Gene CNV Profiles	1.0	2.4977
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894521
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13069
3-M syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CTCF	ENCODE Transcription Factor Targets	1.0	null
A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58638
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.65926
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83083
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.99952
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.75791
CTV1DM	DepMap CRISPR Gene Dependency	1.0	4.21915
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48357
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-LGG_MYB_L1_deletions-Unnamed_2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital diaphragmatic hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21168
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7743
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.982807
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.525
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860253
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04665
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902143
TE6	CCLE Cell Line Gene CNV Profiles	1.0	1.67038
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80461
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34541
REST	ChEA Transcription Factor Targets	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04665
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.80089
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81065
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33634
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56128
NCIH2171	CCLE Cell Line Gene CNV Profiles	1.0	1.59533
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.73793
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.678
KPL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47487
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
detection of chemical stimulus involved in sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922372
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65984
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Thyroid lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.663
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894521
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971777
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12988
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7048
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63752
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TWIST1_01_252	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61209
CALU6	DepMap CRISPR Gene Dependency	1.0	2.39041
BICR16	DepMap CRISPR Gene Dependency	1.0	5.0479
olfactory receptor activity	GO Molecular Function Annotations 2025	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7284
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6157
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.875153
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6179
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6724
sensory perception of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9702
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78017
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1105
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850713
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942837
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF1_01_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61629
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13069
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.38
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.73234
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7363
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21506
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.40466
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01392
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74105
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950912
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16981
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46389
Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1002
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23961
Lung squamous cell carcinoma_LUSC_TCGA-18-3419-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6145
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	2.97176
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7415-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893251
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VB-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.8921
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23961
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.12225
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96407
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837934
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	3.40136
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.41065
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8621
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26679
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	2.12225
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17131
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54833
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48769
MEL270	DepMap CRISPR Gene Dependency	1.0	6.66372
NCI-H1838	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.32901
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66395
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833857
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11262
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978492
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971777
biological_process	GO Biological Process Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902649
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
KYSE410	DepMap CRISPR Gene Dependency	1.0	3.42177
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5347
EN	DepMap CRISPR Gene Dependency	1.0	2.51653
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9576
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.97337
molecular_function	GO Molecular Function Annotations 2015	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.912766
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97439
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44344
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57003
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.77557
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859279
membrane	GO Cellular Component Annotations 2015	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15441
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9373
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.26568
U2904	DepMap CRISPR Gene Dependency	1.0	3.7786
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44423
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8811
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.055
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.774961
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02506
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877117
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44394
NCIH1694	DepMap CRISPR Gene Dependency	1.0	3.01432
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.93054
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Angioedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
SET2	DepMap CRISPR Gene Dependency	1.0	2.2532
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.97406
TE11	CCLE Cell Line Gene CNV Profiles	1.0	1.78637
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35239
sensory perception	GO Biological Process Annotations 2015	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2065
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856317
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3031
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841827
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31427
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877117
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.41764
detection of chemical stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68243
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868911
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37018
C1 inhibitor deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.035
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893251
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48971
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	5.96905
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2166
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.55771
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42307
odorant binding	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0241
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75806
cell part	GO Cellular Component Annotations 2015	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.4857
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79646
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18691
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.50363
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887115
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9935
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33019
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02421
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.993953
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.888096
CALU1	DepMap CRISPR Gene Dependency	1.0	4.04014
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99521
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02877
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2442
Olfactory transduction	KEGG Pathways 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09166
BL70	DepMap CRISPR Gene Dependency	1.0	2.05028
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.978052
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01852
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68596
detection of chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79646
tocilizumab_homo sapiens_gpl6244_gse25160	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48635
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10502
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2328
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77986
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESRRA_01_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.89221
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01392
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.001
Signaling by GPCR	Reactome Pathways 2014	1.0	null
UMUC13	DepMap CRISPR Gene Dependency	1.0	3.4915
sensory perception of smell	GO Biological Process Annotations 2015	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	2.53847
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48806
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3814
GLI2_01_143	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.71091
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01392
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54451
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40693
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23961
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8216
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935138
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.50157
Diaphragm disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
CHL1DM	DepMap CRISPR Gene Dependency	1.0	2.36547
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887115
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.67717
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918829
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6281
detection of stimulus involved in sensory perception	GO Biological Process Annotations 2015	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0168
U87MG	DepMap CRISPR Gene Dependency	1.0	3.10629
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35239
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0365
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04781
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846172
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5833
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4273
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02216
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63872
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14195
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.663
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9471
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.04972
signal transduction	GO Biological Process Annotations 2015	1.0	null
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.59719
Brain Lower Grade Glioma_LGG_TCGA-DH-5142-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8738
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935138
Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0401
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12712
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17454
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894521
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879695
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3681
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971777
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88625
biological regulation	GO Biological Process Annotations 2015	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07917
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05882
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6902
NCIH1838	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Olfactory Signaling Pathway	Reactome Pathways 2014	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6115
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.50086
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.69967
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7808
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50358
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.84
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2695
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24692
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7717
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13069
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.888096
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.58014
PFSK1	DepMap CRISPR Gene Dependency	1.0	3.15348
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GATA3_01_347	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.71359
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1821
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51925
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.5323
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33799
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49139
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.50467
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
C32	DepMap CRISPR Gene Dependency	1.0	3.11893
WM115	DepMap CRISPR Gene Dependency	1.0	2.79907
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	2.10045
NCIH157DM	DepMap CRISPR Gene Dependency	1.0	2.5189
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0981
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14195
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53782
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7082-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7573
Complement deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6221
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0789
lung	GTEx Tissue Gene Expression Profiles	-1.0	-0.888096
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29203
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18702
PSN1	DepMap CRISPR Gene Dependency	1.0	6.24683
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.994842
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39833
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88769
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85795
single-organism process	GO Biological Process Annotations 2015	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942255
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05722
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884734
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13487
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53782
Hereditary angioedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862254
NCIH1944	DepMap CRISPR Gene Dependency	1.0	3.04191
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894521
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
olfactory receptor activity	GO Molecular Function Annotations 2023	1.0	null
ESCRT IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
S117	DepMap CRISPR Gene Dependency	1.0	3.24762
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.927194
L33	DepMap CRISPR Gene Dependency	1.0	2.46717
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39338
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06168
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.07104
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35003
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-0.888096
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17454
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	4.69368
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894521
system process	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.42993
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60839
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7754
COLO320	DepMap CRISPR Gene Dependency	1.0	5.69735
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.25669
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8831
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49887
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.12225
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25679
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48496
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6023-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6010-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Dura mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85402
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7102-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60225
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
KU1919	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42499
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20242
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7727
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.115
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939892
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46968
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66395
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7566
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7162
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20722
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8275
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.068
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02508
NCIN87	DepMap CRISPR Gene Dependency	1.0	3.12633
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47472
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1708
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS936T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.51964
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.36041
PBX1	ChEA Transcription Factor Targets	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5093
Longissimus thoracis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
HGC27	DepMap CRISPR Gene Dependency	1.0	3.86945
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887115
LXF289	DepMap CRISPR Gene Dependency	1.0	2.14438
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5976-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9188
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58592
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3005
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1493
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04781
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0215
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865003
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3079
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971777
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21506
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.67006
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6364
SNU626	DepMap CRISPR Gene Dependency	1.0	4.73346
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952969
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942837
OCIAML3	DepMap CRISPR Gene Dependency	1.0	5.74107
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4298
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63872
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88769
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1254
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.49917
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24015
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51483
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6395-01A-13R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.888096
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84385
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5572
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870902
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5047
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3858
SF126	DepMap CRISPR Gene Dependency	1.0	4.31388
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33634
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4316
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0742
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1198
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6561
PA1	DepMap CRISPR Gene Dependency	1.0	2.70411
TE4	CCLE Cell Line Gene CNV Profiles	1.0	2.41602
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14308
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09375
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79646
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0929
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08771
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13908
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03004
olfactory receptor activity	GO Molecular Function Annotations 2015	1.0	null
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Unnamed_6_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978492
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01886
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4305
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.39568
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
MELHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35643
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6354
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
Signal Transduction	Reactome Pathways 2014	1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.377
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894521
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7842
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830786
KMRC3	DepMap CRISPR Gene Dependency	1.0	2.0144
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.547
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23961
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2206
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.133
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978492
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	2.15937
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26679
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6623
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3115
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.93772
response to stimulus	GO Biological Process Annotations 2015	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4082
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.40625
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877117
CHK1_KD_GSE54267_671_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Arachnoid mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.85385
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16103
cyclosporine_homo sapiens_gpl4133_gse25200	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05003
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69434
Olfactory receptor	InterPro Predicted Protein Domain Annotations	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.67187
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10302
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02334
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.80414
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11926
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20284
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40607
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS299	DepMap CRISPR Gene Dependency	1.0	2.38954
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.909
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60397
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1576
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3523
