association dataset threshold value standardized value ventrolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68305 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3737 BRD-K91879432 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05751 BRD-K01166365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5263 TARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8726 TP63_NULL MUTATION_GDS1434_308_mouse_Skin at embryonic age E18.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K18533510 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36944 BRD-K97576000 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4565 BRD-A63759745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20583 Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6978 GSE149442_1_v_0_gdpd3_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K94062017 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13835 GM1600 BioGPS Cell Line Gene Expression Profiles 1.0 1.04249 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GARRE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81802 BRD-K22087390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1437 GSE201361_0_v_1_mpst_mouse RummaGEO Gene Perturbation Signatures -1.0 null Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0541 BRD-K22508525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33744 COL5A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70726 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24955 SCS214 DepMap CRISPR Gene Dependency 1.0 3.00134 TMEM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28029 Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7669 Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02291 BRD-K29760532 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35238 ZNF777 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00601 Brain Lower Grade Glioma_LGG_TCGA-HT-7689-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K55877261 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50423 KMS18 DepMap CRISPR Gene Dependency 1.0 2.0473 BRD-K30510226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85931 layer 6 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84448 NUMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53373 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RMUGS DepMap CRISPR Gene Dependency 1.0 2.73217 ALCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.662 NDUFAB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27963 Mediodorsal nucleus of the thalamus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25659 SAP30 ENCODE Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.269 mantle zone of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55448 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41771 BRD-K90902537 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58621 Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 BRD-K09250647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.89582 ATAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98148 ENPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30859 EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8175 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20159 Olfactory transduction KEGG Pathways 2026 1.0 null HS895T CCLE Cell Line Gene Expression Profiles 1.0 1.64777 ZNF513 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59128 NDST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15006 sensory perception of chemical stimulus GO Biological Process Annotations 2025 1.0 null GTF2H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38118 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3378-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CSNK1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50465 SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11182 BRD-K63754039 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11135 BRD-K63730594 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10415 BRD-K71345532 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2873 BRD-K72792753 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46686 BRD-K62000282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31532 BRD-K71538933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32028 lateral septal nucleus, intermedio-ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.2361 ZNF800 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62187 LRRC73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14328 GSE124471,GSE124488_2_v_3_lats1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6938 NPIPB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81265 GPCRs, Class A Rhodopsin-like(Mus musculus) WikiPathways Pathways 2014 1.0 null mantle zone of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12331 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3952 GNRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79704 DHFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76136 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19478 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -1.89067 Olfactory receptor InterPro Predicted Protein Domain Annotations 1.0 null layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65877 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07016 Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K66207462 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56304 BRD-K09250623 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21249 GSE62843,GSE64371_2_v_5_furan_mouse RummaGEO Drug Perturbation Signatures 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.422 PARPBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91135 RING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.71584 BRD-K97064059 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -6.25272 GSE226091,GSE226092_0_v_1_sall1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 50.4488 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.33022 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8054 BRD-K94518115 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58058 Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39605 NEUROG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4168 hsa-miR-3183 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 lateral part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55448 TFAP2A-17053090-MCF7-human ChEA Transcription Factor Binding Site Profiles 1.0 null r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22988 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K27849471 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34098 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8164-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-6689-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K17482962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.23671 DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Parabrachial nucleus, lateral division, dorsal lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0931 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K96218803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56858 BRCA1_DEPLETION_GDS3791_502_human_Hela cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K91268803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32047 HSC3 CCLE Cell Line Gene CNV Profiles 1.0 1.34775 BRD-K75041300 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35402 PSME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86704 PSKH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55992 SS18L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26958 KLF15_KO_GDS4780_419_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HCC1806 CCLE Cell Line Gene CNV Profiles 1.0 2.75949 DDX47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02299 BRD-K02624294 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19985 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7686 U87 BioGPS Cell Line Gene Expression Profiles 1.0 0.949765 ICC108 DepMap CRISPR Gene Dependency 1.0 3.91442 PTTG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30054 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4297 sensory perception of smell GO Biological Process Annotations 2025 1.0 null DIRAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16796 BRD-K38935430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0098 GSE182680,GSE182683_7_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null Foxf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.851 hsa-miR-422a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GLCCI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58724 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59942 Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37816 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null TXNDC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9638 XBP1_OE_GDS5065_273_mouse_F424a adipocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31851 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20341 BRD-K85513726 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5649 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8811 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74042 NCOA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2211 BCAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62999 HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.941255 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LU99 CCLE Cell Line Gene Expression Profiles 1.0 1.94917 FLI1 ChEA Transcription Factor Targets 1.0 null Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.3915 KASUMI-1 GDSC Cell Line Gene Expression Profiles -1.0 -1.82567 C1GALT1C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15462 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12896 STOM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2626 BRD-K51535480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41204 LIPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35297 GSE182680,GSE182683_10_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K19269952 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35613 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2025 1.0 null RWDD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72131 GNB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32011 septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19994 Lung adenocarcinoma_LUAD_TCGA-55-1595-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU2F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21199 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0855 superficial stratum of r5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11012 BRD-K94751306 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.11953 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K25016708 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22257 CTCF ENCODE Transcription Factor Targets 1.0 null AGFG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5213 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98237 BRD-K76521932 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74707 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.678 BRD-K38791044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48784 FAM236B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47945 TP53BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90072 ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1851 BRD-K16727544 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.93233 UBB_KO_GDS3906_494_mouse_Testis - 21 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.6667 intermediate stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.27238 TE-441-T COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PABPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72263 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14132 NCIH1355 CCLE Cell Line Gene CNV Profiles -1.0 -1.97429 BRD-K52157065 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.45262 BRD-K44652223 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24825 Fumarate reductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.546 BRD-K19946529 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27634 hsa-miR-378i TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.85323 BRD-K35288606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.77595 orbital frontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02989 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.11955 BRD-K94766933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30806 icSARS CoV_36Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.65538 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0359 ZNF572 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16608 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BXPC3 DepMap CRISPR Gene Dependency 1.0 2.24326 BRD-K52154207 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.02206 Acute Myeloid Leukemia_LAML_TCGA-AB-2874-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null detection of chemical stimulus GO Biological Process Annotations 2015 1.0 null bed nucleus of the stria terminalis, mediocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29034 GSE195786_0_v_2_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null NEK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40447 CS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11767 detection of stimulus GO Biological Process Annotations 2015 1.0 null CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.42508 MREG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30578 CEBPB ENCODE Transcription Factor Targets 1.0 null BRD-K99074976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22953 FUOV1 CCLE Cell Line Gene CNV Profiles 1.0 1.9044 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958179 FOXO1_KD_GDS2720_477_mouse_LSK GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.51328 ATG12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76663 RORA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35969 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3628 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K84090286 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30204 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58825 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PJ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A76899420 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19793 MED19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23317 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07526 Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGFBI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66591 SOWAHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43647 BRD-K65891102 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30266 UBAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89016 BRD-K47804666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14099 PPARGC1A_KO_GDS2391_299_mouse_brain striatum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RIOK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4741 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11475 BRD-K77519898 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30409 rhombomere 7 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29087 MCRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99814 BRD-K58324650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.64091 MLST8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88516 POTEI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83636 U251 COSMIC Cell Line Gene Mutation Profiles 1.0 null EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11347 Prostate adenocarcinoma_PRAD_TCGA-KC-A4BN-01A-61R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DVL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52389 DSTYK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01158 NIFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05604 PRDM16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18467 BRD-K36855468 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39655 POU5F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52164 Nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.518 BRD-K37433647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.25344 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KYSE510 CCLE Cell Line Gene Expression Profiles 1.0 1.46463 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ILVBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26802 FBN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52317 BRD-K91973560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54581 BRD-K13873561 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39802 CCRT CEM BioGPS Cell Line Gene Expression Profiles -1.0 -1.50603 mantle zone of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12995 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865026 Posterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43601 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K82392710 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32764 CNOT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64595 CAR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4267 GSE201042_6_v_10_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TMEM39A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5118 POLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.61617 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.2633 Kidney renal papillary cell carcinoma_KIRP_TCGA-O9-A75Z-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K16332856 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65886 BRD-K81120201 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16696 Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRC8D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2592 GSE133516_5_v_3_kat7_human RummaGEO Gene Perturbation Signatures -1.0 null OE33 DepMap CRISPR Gene Dependency 1.0 2.68342 TIGD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33482 BRD-K66993610 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06186 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3148 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BZ-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null VASN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07814 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.6919 BRD-K06208179 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.62871 RBIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38232 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3338 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7117 BRD-K93283197 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71876 ANAPC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91092 MKN7 CCLE Cell Line Gene CNV Profiles 1.0 2.4531 RT11284 CCLE Cell Line Gene CNV Profiles -1.0 -1.41349 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.93214 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824921 CSRNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26627 MEG-01 GDSC Cell Line Gene Expression Profiles -1.0 -1.66688 molecular_function GO Molecular Function Annotations 2015 1.0 null hsa-miR-376b TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 USP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05165 BRD-K22449045 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58362 AU565 DepMap CRISPR Gene Dependency 1.0 2.27806 BRD-K23196166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53365 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8954 GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-A78125048 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.65161 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.833114 BRD-K64571715 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.37503 KLC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28202 ventral posterolateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07015 HDAC6 ENCODE Transcription Factor Targets 1.0 null BRD-K03312699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.51899 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15555 BRD-K83341545 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07505 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IL2_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K33770771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47446 BRD-K97256018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52564 CAL-33 GDSC Cell Line Gene Expression Profiles 1.0 1.92585 Subceruleus nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19121 membrane GO Cellular Component Annotations 2015 1.0 null RXRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33365 r6 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4143 BRD-K12384030 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27668 BRD-K62358193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00991 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.80744 primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.997284 BRD-K81131499 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46079 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null STAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60235 Pectoral muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.759 ZNF474 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23856 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17275 THAP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68548 BRD-K88070218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19207 superficial stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4143 Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null suprachiasmatic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07526 Primary visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40564 GSE139992_1_v_0_mboat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.237 POLDIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10398 dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.93572 Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5017 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5EZ-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K62472719 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81731 GSE174498,GSE174500_3_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.25957 RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0139 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K40804250 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33871 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null oligomycin-442 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-A55025683 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.458 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K08940439 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67401 Appendix BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.05202 Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF326 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33991 SF295 GDSC Cell Line Gene Expression Profiles -1.0 -1.78981 hsa-miR-4733-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 mantle zone of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0238 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.31888 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3628 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04402 BRD-K68617666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.17711 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.1003 H2804 COSMIC Cell Line Gene Mutation Profiles 1.0 null CCDC85C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18629 CHD1-26751641-CHIP-SEQ-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7474 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC9A3_KO_GDS3323_495_mouse_colon GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hippocampus (hippocampal formation)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.924897 BRD-K43284834 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80892 LAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43042 59M CCLE Cell Line Gene Expression Profiles -1.0 -1.82528 UFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38634 H2AFZ ENCODE Transcription Factor Targets 1.0 null ATXN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01892 CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null UBE3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12126 BRD-K65445351 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43955 r1 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47587 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0 SYCP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61798 GSE62843,GSE64371_4_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null uterus GTEx Tissue Gene Expression Profiles 1.0 1.04362 Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.9742 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2769 BRD-K73075421 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26307 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8084 HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829472 BRD-K86004174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43396 ACC3 BioGPS Cell Line Gene Expression Profiles 1.0 1.43221 BRD-K25127909 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09711 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6569 hippocampus (hippocampal formation)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.995906 GCNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01919 BRD-K73357447 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09835 MEF2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.8383 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8227 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 internal globus pallidus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90678 GSE172189_0_v_1_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19994 ZSCAN30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07412 ZNF821 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41493 TSTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37225 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K01237500 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.37917 BRD-K89660028 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.34029 BRD-K10058823 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31067 BRD-K85527716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.023 BRD-K13559806 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05381 Prelimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34717 KYSE140 DepMap CRISPR Gene Dependency 1.0 2.6863 COG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02656 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-11A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12079 Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAPK8IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12543 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.98491 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-7027-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K16605233 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10943 Sarcoma_SARC_TCGA-DX-A6BG-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A09115727 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03094 BRD-K59434830 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19536 OTULINL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43471 SKMEL28 CCLE Cell Line Gene CNV Profiles 1.0 1.39165 r10 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28113 HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.539544 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K48880196 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82879 ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4361 FSBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85791 BRD-K47212522 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10504 KCIMOH1 CCLE Cell Line Gene Expression Profiles 1.0 1.40743 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.867598 CALU6 DepMap CRISPR Gene Dependency 1.0 2.65797 Lateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00208 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31776 MTMR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.56611 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866297 BRD-K87447060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5186 BRD-K72194126 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10396 TUBA1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96659 AP3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65996 Dmbx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.1086 GUCA1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.81151 BRD-K26195700 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72899 FN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82375 BRD-K65368100 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68514 OTX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7833 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.16289 ZFX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86602 BRD-K14255526 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.05485 IDH3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72695 PROM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09703 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0656 Olfactory Signaling Pathway Reactome Pathways 2014 1.0 null AMIGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45537 BRD-K91490997 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46783 BRD-K28467592 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73576 SIRT1_KO_GDS3666_295_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K61020385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74524 GSE104022_1_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K68086276 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10104 BRD-K33805386 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.7157 GPCRs, Other(Mus musculus) WikiPathways Pathways 2014 1.0 null FUBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38753 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0035 VMRCLCD CCLE Cell Line Gene Expression Profiles -1.0 -2.93911 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5429 BRD-K93335719 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.08833 SIRPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79693 BRD-K70819166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43568 BRD-K83183132 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07196 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06599 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74285 BRD-K46588240 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54369 SLR26 DepMap CRISPR Gene Dependency 1.0 2.8423 MSMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36099 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane LOCATE Predicted Protein Localization Annotations 1.0 null PANC1 CCLE Cell Line Gene CNV Profiles 1.0 2.06406 response to stimulus GO Biological Process Annotations 2015 1.0 null SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39366 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r4 part of medial paralemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67136 H1-10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08049 IRF1-21803131-MONOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null OVOL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70792 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.49373 769P DepMap CRISPR Gene Dependency 1.0 3.51499 BRD-K30853940 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52674 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39095 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4327 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 C5orf22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88778 lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20415 BRD-K60188481 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65144 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23135 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7529 PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null SPCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7594 BRD-K02624724 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29604 ING5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80167 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K12281552 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44879 PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3 Rummagene Transcription Factor Associations 2026 1.0 null BON-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.534 RERFLCAI CCLE Cell Line Gene CNV Profiles 1.0 1.39505 BRD-K21479004 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96259 KNS-81-FD COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K28006645 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57643 BRD-K29728947 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77527 intermediate stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4198 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3017 GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null HTRA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64328 PTEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77463 TGOLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.59612 NCVADR RES BioGPS Cell Line Gene Expression Profiles -1.0 -0.940531 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null BRD-K55316222 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55973 NKX2-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12046 inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.56927 BRD-K47165178 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.7024 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65809 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7766 CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KBTBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94541 ZNF394 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20883 BRD-K50474387 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23363 RAD51C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.295 superficial stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36105 CEBPB_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.904277 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.6163 intermediate stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20211 single-organism process GO Biological Process Annotations 2015 1.0 null ACTL6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03895 HOXC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18343 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7247 COLO824 DepMap CRISPR Gene Dependency 1.0 5.51039 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.00592 Exocrine glandular secretion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.728 ZNF266 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22286 layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38219 Posterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01537 BRD-K94196749 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5133 BRD-K08971733 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39279 786-0 GDSC Cell Line Gene Expression Profiles 1.0 1.43942 ADRA2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07334 UACC812 CCLE Cell Line Gene Expression Profiles -1.0 -1.70704 RNF166 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10858 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959694 ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6221 sensory perception GO Biological Process Annotations 2015 1.0 null NCIH292 CCLE Cell Line Gene CNV Profiles 1.0 1.4281 Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29073 CLOCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24066 intermediate stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12705 intermediate stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.02964 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TC-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K63277230 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07912 NCI-H716 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.567 SIHA COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K11636255 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19864 PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null NR2E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20834 CPSF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28125 ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32528 BRD-A77164655 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.62485 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1543 CCDC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99633 GB1 CCLE Cell Line Gene Expression Profiles -1.0 -2.13111 Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14583 mantle zone of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17031 BRD-K69536411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.40723 BRD-K76755163 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26546 GSE146074_10_v_3_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R0-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PXMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05473 no-11 GDSC Cell Line Gene Expression Profiles 1.0 1.44215 GLRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35332 r7 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53588 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1912 TAF6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06682 MVD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40365 BRD-K15609977 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14571 Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42192 Brain Lower Grade Glioma_LGG_TCGA-HT-7877-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RI1 DepMap CRISPR Gene Dependency 1.0 3.99543 IDRA-21 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40899 CAPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24036 KCTD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57171 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07095 CJM DepMap CRISPR Gene Dependency 1.0 2.38672 BRD-K54484272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45545 Brain Lower Grade Glioma_LGG_TCGA-DU-7008-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LIVF001-028 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42847 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K79213964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.39428 p3 part of the ZL core Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93928 Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP53BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36172 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50066 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null BRD-K42081955 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.84493 Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RET CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61594 BRD-K29301364 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15243 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9944 GPR150 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74496 BRD-K86002795 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.09415 EW-1 GDSC Cell Line Gene Expression Profiles 1.0 1.74671 rostral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83699 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55111 r2 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75016 supragenual nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02875 Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HL60 BioGPS Cell Line Gene Expression Profiles -1.0 -2.07549 TUNAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87637 DMWD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50404 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.944243 GSE154767_2_v_3_adam10_mouse RummaGEO Gene Perturbation Signatures 1.0 null SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.6814 TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45041 GSE182680,GSE182683_10_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7946 MTERF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.22479 BRD-K72892670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76312 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.956408 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9716 SCRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50992 Anterior olfactory nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6375 COLO205 BioGPS Cell Line Gene Expression Profiles 1.0 0.909437 MELJUSO CCLE Cell Line Gene Expression Profiles 1.0 1.44712 OS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06578 Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.65291 reticular complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12743 SF126 DepMap CRISPR Gene Dependency 1.0 2.51793 CSNK1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0279 GFER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47354 BRD-A06232236 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08358 CEBPD ENCODE Transcription Factor Targets 1.0 null NEK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24526 TMEM123 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73636 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824921 chlorambucil-3788 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20159 BRD-K50443235 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62323 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.9791 PDSS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16532 SF268 CCLE Cell Line Gene CNV Profiles 1.0 1.69826 BRD-K44705560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32321 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86257 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A268-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.956937 r10 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26682 HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.70838 NACA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70121 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7121 NDUFB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75053 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24993 MDAMB468 DepMap CRISPR Gene Dependency 1.0 5.12313 Posterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37578 SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null mantle zone of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75621 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 SPSB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98457 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2753 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12046 143B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83073 JUND-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ASCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25072 GSE233679_5_v_8_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null RETSAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97062 AM-095 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38699 Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CORL23 DepMap CRISPR Gene Dependency 1.0 2.07092 ChaGo-K-1 GDSC Cell Line Gene Expression Profiles 1.0 1.78654 SW1463 GDSC Cell Line Gene Expression Profiles -1.0 -1.43912 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10751 BRD-K46348476 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39695 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.6595 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5914 superficial stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62464 Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.54843 GSE140651,GSE140653_2_v_0_med1_human RummaGEO Gene Perturbation Signatures 1.0 null BRD-K23232542 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79287 Lung adenocarcinoma_LUAD_TCGA-78-7220-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rhinencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.87 anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.13639 Accessory facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23091 BRD-K40251180 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28044 ARRDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69579 TBX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1418 MAPKAPK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6722 Crx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.5273 TRAFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46076 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4161-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RA-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68692 r3 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43089 r4 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28113 GSDMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02334 JHH6 CCLE Cell Line Gene CNV Profiles 1.0 1.81571 BRD-K41888813 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09325 JHH5 CCLE Cell Line Gene CNV Profiles 1.0 1.66226 BRD-K05050615 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.49081 MJ CCLE Cell Line Gene Expression Profiles 1.0 1.63542 KMS27 CCLE Cell Line Gene CNV Profiles 1.0 1.35365 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42196 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0849 SHMAC5 DepMap CRISPR Gene Dependency 1.0 2.5042 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null JIMT1 CCLE Cell Line Gene CNV Profiles -1.0 -2.23939 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846466 NCI-H1694 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20844 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77O-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6552 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA6_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null ANKRD23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27075 BRD-K07160568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2318 Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27002 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1133 BRD-K89584810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.24585 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9144 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.956937 BRD-K92632379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20871 TE1 CCLE Cell Line Gene CNV Profiles -1.0 -2.04809 SNU620 DepMap CRISPR Gene Dependency 1.0 6.08542 BRD-K45328741 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04102 BRD-K56536691 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34006 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3779 BRD-K29685390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41281 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9034 GSE111102,GSE111105_1_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12861 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22234 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AA-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K76202128 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52986 BRD-K65438558 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06997 SIX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73998 SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.845347 BRD-K28785305 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.94822 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.1208 primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870624 hsa-miR-378h TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 BRD-K76713927 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.80723 BRD-K12181036 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1101 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.644 UBE2Z CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8093 PANC1 BioGPS Cell Line Gene Expression Profiles -1.0 -1.07181 BRD-K08829593 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26648 Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null ZNF844 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64766 HT-29 GDSC Cell Line Gene Expression Profiles 1.0 1.7722 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19553 SubthalamicNucleus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.974128 IGF1_OE_GDS3484_538_human_MCF-7 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Salivary_Gland-plasma cell Tabula Sapiens Gene-Cell Associations 1.0 0.717225 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K34761198 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36431 ABCD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00313 hsa-miR-378 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 F12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67726 ARV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26798 CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46945 HCC2998 BioGPS Cell Line Gene Expression Profiles -1.0 -1.31089 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2985 BRD-K44779670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37835 CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K34234678 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43843 SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 1.42508 g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null shell of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26247 PLD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04502 TSHZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97415 FXR MotifMap Predicted Transcription Factor Targets 1.0 null PPP1R11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64414 MDAMB453 CCLE Cell Line Gene CNV Profiles -1.0 -1.80557 BRD-K83619973 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00011 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.2582 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZW-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.3313 Sarcoma_SARC_TCGA-MB-A8JK-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.10654 Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05269 KARPAS-45 GDSC Cell Line Gene Expression Profiles -1.0 -1.46996 ZNF79 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96694 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01267 BRD-K84775364 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61601 SSH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35791 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.906869 r7 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17454 NOCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.923 Brain Lower Grade Glioma_LGG_TCGA-HT-7474-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K50603336 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.03566 Artery - Coronary GTEx Tissue Gene Expression Profiles 2023 1.0 1.44189 oxybutynin-1551 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RPL12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90445 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100623_PCx_no dementia_TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1494 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.61387 GSE174498,GSE174500_5_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null JURLMK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.58944 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC39A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71676 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.837039 GSE182680,GSE182683_10_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE175787_5_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 AMO1 DepMap CRISPR Gene Dependency 1.0 3.27383 CEP57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84921 RP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0464 BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2569 BRD-K75900952 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07014 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K37961770 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2015 TFAP2A ChEA Transcription Factor Targets 1.0 null H3K9me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.9651 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54068 layer 6b of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72971 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880786 Tongue epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.919 LS123 CCLE Cell Line Gene Expression Profiles -1.0 -1.61176 Brain Lower Grade Glioma_LGG_TCGA-RY-A847-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23599 BRD-K31606237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.36184 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8603 BRD-K50291875 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10207 BRD-K26689527 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29813 NOTCH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08804 TMEM138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.18894 Olfactory Signaling Pathway Reactome Pathways 2024 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52528 Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73A-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.2247 BRD-A04231641 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17742 GSE111660_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26919 A427 GDSC Cell Line Gene Expression Profiles 1.0 1.63147 HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37088 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.946828 TIPRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78437 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.42414 MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7188 PJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20807 JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K39411863 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.30812 RASGRF1_KD_GDS2816_287_human_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.969642 Medial group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07071 prostate GTEx Tissue Gene Expression Profiles 1.0 0.850727 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null signal transduction GO Biological Process Annotations 2015 1.0 null NCIH1703 CCLE Cell Line Gene CNV Profiles -1.0 -1.93226 BRD-K41311678 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.743 TP53BP1_KD_GSE54268_670_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null r10 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12331 GSE165682_2_v_5_ptbp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-A48Z-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC61G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31311 MT-ATP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31003 BRD-K24743998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55372 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2023 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.870336 NUGC4 CCLE Cell Line Gene Expression Profiles 1.0 1.47552 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PRC2_SUZ12_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null PCDHB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17642 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23061 mediodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2216 OR2A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19321 BRD-K96096022 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.27541 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7841-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148692,GSE148695_5_v_4_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K62374815 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40952 layer 5 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22447 Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K43989220 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22274 Signal Transduction Reactome Pathways 2014 1.0 null BRD-K69093885 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27421 superficial stratum of r4BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36646 PPP1R3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76875 MEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18484 LOUCY GDSC Cell Line Gene Expression Profiles -1.0 -2.15223 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48916 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K17954972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5653 BRD-K28924192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40501 BRD-K79497053 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06197 BRD-K39498165 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02976 GSE171837_3_v_1_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.32122 BRD-K95350313 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27141 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K66538269 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29979 anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.93572 BCL6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62161 superficial stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20211 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE62843,GSE64371_4_v_0_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE147056_4_v_1_actl6b_mouse RummaGEO Gene Perturbation Signatures -1.0 null EIF2AK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07272 Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRC8E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01453 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4703-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100305_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.54862 IRF1-21803131-MONOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K18601936 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10011 BRD-K79807180 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06389 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4981 Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANAPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11679 optic fiber layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2745 BRD-K59821747 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41908 BRD-K48046422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27742 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.7109 HMC18 CCLE Cell Line Gene Expression Profiles 1.0 1.35895 Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43592 Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11363 intermediate stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00746 BRD-K89366259 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16613 REH GDSC Cell Line Gene Expression Profiles 1.0 1.44621 IgG B cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.649 BRD-K04272258 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73309 BRD-K83238251 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.84332 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5847 IL21_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null GSE180951_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null BRD-K39863565 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.99319 EPHX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14487 BRD-K87180723 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46243 SNU719 DepMap CRISPR Gene Dependency 1.0 3.48497 Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17031 BRD-A55063801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07669 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.981283 GSE123022,GSE123030_2_v_0_trem2_mouse RummaGEO Gene Perturbation Signatures 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE118765_1_v_5_rreb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.61077 prethalamic (p3) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75791 hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17726 TUBGCP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17338 Brain Lower Grade Glioma_LGG_TCGA-RY-A843-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNJ14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4504 hsa-miR-361-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 BRD-K15350548 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.94292 HCC2814 CCLE Cell Line Gene CNV Profiles 1.0 1.53958 SOD2_KO_GDS1080_128_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abducens motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19039 Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05759 multicellular organismal process GO Biological Process Annotations 2015 1.0 null HSD11B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33115 BRD-K23393992 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04682 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5644 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0843 LUDLU1 DepMap CRISPR Gene Dependency 1.0 2.73507 hsa-miR-4714-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 BRD-K62418408 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21241 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.921 Presubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60229 Reticular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.28476 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5881 presubiculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2862 A-61603 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.44468 transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.8706 RPL34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94626 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SYNGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28487 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866297 STAT6_01_85 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.61069 HSPBAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23845 ANLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58428 imatinib_homo sapiens_gpl96_gds3042 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C2orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4332 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6105 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18628 GSE232472_1_v_2_apoe_mouse RummaGEO Gene Perturbation Signatures -1.0 null TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -2.04933 BRD-K76691746 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38814 BRD-K73604422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17294 ALDH1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99777 BRD-K06425073 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00698 olfactory GeneRIF Biological Term Annotations 1.0 null ADM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27698 periventricular stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19109 BRD-K29083370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.89513 H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A67787745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29855 Presubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26216 SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17852 ATF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8081 CSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08384 GOLGA6L9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10916 Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP2A-17053090-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 1.0 2.28364 Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K17060750 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18295 BRD-K64449549 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22839 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44071 GPCRs, Class A Rhodopsin-like(Homo sapiens) WikiPathways Pathways 2014 1.0 null P12ICHIKAWA CCLE Cell Line Gene Expression Profiles 1.0 1.56312 LN443 CCLE Cell Line Gene Expression Profiles -1.0 -2.31819 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.90665 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3019 RCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4331 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67094 Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Atherosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.135 GSE174498,GSE174500_2_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22103 SETD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19964 IPMK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28509 JVM2 CCLE Cell Line Gene Expression Profiles 1.0 2.12229 Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18048 BRD-K78003637 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.04493 MICA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16989 SPOPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21711 FAM217B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37271 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2023 1.0 null MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3015 PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8 Rummagene Transcription Factor Associations 2026 1.0 null UHO1 DepMap CRISPR Gene Dependency 1.0 2.46757 BRD-K74299234 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00696 ZDHHC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36902 Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC0203 CCLE Cell Line Gene CNV Profiles 1.0 2.2928 superficial stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03061 superficial stratum of PrS (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2862 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2015 1.0 null SLC16A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66662 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31967 Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-378e TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 BRD-K64748422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01485 OVMANA CCLE Cell Line Gene Expression Profiles 1.0 2.49477 AR-35413990-HUMAN-ARPOSCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null PRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19199 Prostate adenocarcinoma_PRAD_TCGA-V1-A8ML-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82469 BRD-K49103797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.96908 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.31331 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.1375 GSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02416 RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.087 COLO775 CCLE Cell Line Gene Expression Profiles -1.0 -1.45596 NNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81448 BRD-K75999096 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03209 SKNEP1 DepMap CRISPR Gene Dependency 1.0 2.58111 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A43135847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49238 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4143 intermediate stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02723 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20159 CAMSAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27397 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3282 SW962 GDSC Cell Line Gene Expression Profiles 1.0 2.31896 GRPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3571 superficial stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04045 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.1231 HNRNPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30304 BRD-K37387086 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07214 KIFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91484 GTSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.454 RACK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92807 posteroventral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29994 IRF1 ChEA Transcription Factor Targets 1.0 null GPCRs class A rhodopsin like WikiPathways Pathways 2024 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -1.1671 alar plate of p3 (alar prethalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59045 Lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11585 BRD-K27881972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17139 dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.853408 Nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.525 PLC-PRF-5 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.805 layer 4 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2046 HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.846283 EGFR_druginhibition_83_GSE27640 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.71015 BRD-K97241181 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.14507 ATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2337 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Brain Lower Grade Glioma_LGG_TCGA-DU-A6S3-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K41709602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.09545 BRD-K98535230 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10138 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K49733809 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.35839 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41158 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89743 FAM78A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58042 ZNF878 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35293 RALB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53796 PRRC2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43409 Pollen tube TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.13 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34264 EIF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19318 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7924 superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31527 BRD-K43435656 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.06346 NCIH292 CCLE Cell Line Gene Expression Profiles -1.0 -2.47935 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00845 BRD-K64992851 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13762 cell part LOCATE Curated Protein Localization Annotations 1.0 null PPP1R3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67825 NCIH1092 CCLE Cell Line Gene Expression Profiles -1.0 -1.69273 PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4447 PTPN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31364 BRD-K25866212 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54925 RNF214 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82647 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.9517 U2AF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91895 SKA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47899 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2792 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 plasma membrane GO Cellular Component Annotations 2015 1.0 null GATA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3524 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9329 RPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72383 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH157DM DepMap CRISPR Gene Dependency 1.0 2.47248 r7 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20415 GSE175787_8_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.977 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4294 periventricular stratum of Dg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29073 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Posterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78174 r2 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04395 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null kidney GTEx Tissue Gene Expression Profiles -1.0 -2.10021 Parasubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19005 S100PBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91121 CIAO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16438 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K43295075 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.12057 BRD-K54898824 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11955 SOSS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.935 alfaxalone-6514 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HNF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02129 biological regulation GO Biological Process Annotations 2015 1.0 null HCC1419 GDSC Cell Line Gene Expression Profiles 1.0 1.68625 Primary visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29034 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.947951 GSE174498,GSE174500_0_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null BICR31 DepMap CRISPR Gene Dependency 1.0 2.46753 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.898 terminal hypothalamus (rostral hypothalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06111 NHE3_Deficiency_GDS3323_599_mouse_Colon GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null UQCRQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78244 VPS35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21934 FKBP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8555 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2025 1.0 null MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K67353973 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38421 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K48019220 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.58426 Expression and translocation of olfactory receptors Reactome Pathways 2024 1.0 null GSE87404,GSE87812_1_v_0_hoxa9_mouse RummaGEO Gene Perturbation Signatures -1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K72050003 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.49235 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0048 BRD-K50191826 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.77595 ACHN BioGPS Cell Line Gene Expression Profiles -1.0 -1.0811 TM2D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18487 OVCAR8 BioGPS Cell Line Gene Expression Profiles -1.0 -0.875314 BRD-K18822985 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.348 Parabrachial nucleus, lateral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0931 MC116 CCLE Cell Line Gene Expression Profiles 1.0 1.8937 CFTR_Deficiency_GDS1843_191_mouse_Lungs - Animals examined at 3 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC56 DepMap CRISPR Gene Dependency 1.0 5.37777 GSE228894_0_v_2_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GS-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null molecular transducer activity GO Molecular Function Annotations 2015 1.0 null GSE107505_3_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null RABGGTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65945 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K88836117 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59235 BRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38033 TMEM25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10414 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.794185 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE147613_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Aortic root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.737 GM2493 BioGPS Cell Line Gene Expression Profiles 1.0 1.21245 Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226770_1_v_6_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null DPPA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40681 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0359 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4405-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A24223049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07281 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7938 hsa-miR-378c TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 PUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40058 Posterolateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30958 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NDUFAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64413 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.57572 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824921 BRD-K66580188 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27617 AMDHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02437 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7229-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67659 Lung squamous cell carcinoma_LUSC_TCGA-66-2737-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC27A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43553 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OX-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VMRCRCZ CCLE Cell Line Gene CNV Profiles -1.0 -3.21027 BRD-K38980456 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33056 BRD-K49745983 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0426 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.40088 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF7IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81306 ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06005 Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null BRD-A66025870 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27957 CCAAT-binding factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.117 STAT3 ChEA Transcription Factor Targets 1.0 null NANS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96245 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.199 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49552 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DLD1 CCLE Cell Line Gene CNV Profiles 1.0 1.35402 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inner hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.801 EFM19 DepMap CRISPR Gene Dependency 1.0 4.22222 HMGN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01056 MAGEB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42601 Psoriasis vulgaris_Skin tissue_GSE14905 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.5183 FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DDX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30067 BT474 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.60816 pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03706 PER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74954 BRD-K01615174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22479 BRD-K13534347 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05292 docebenone LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11713 CCDC113 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50246 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6417 ZNF124 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14748 HEXIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56813 Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.833083 PTPN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49348 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16946 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC25A23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.61118 POLR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29203 BRD-K06863452 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15969 ACADVL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13444 TIMM44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2015 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GPBP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68407 r9 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47587 l2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.57 SIAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6092 Prostate adenocarcinoma_PRAD_TCGA-J9-A8CK-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K48860650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.76525 intercalate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.03305 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26072 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58692 KDM5B ENCODE Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.880962 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.1012 PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null KPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56879 Arteriosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.127 ticlopidine-1895 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MM426 DepMap CRISPR Gene Dependency 1.0 2.44031 BRD-K54712090 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16918 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.788 ZNF697 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66604 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07016 BRD-K82805160 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01437 HUG1N CCLE Cell Line Gene CNV Profiles -1.0 -2.48668 BRD-K59960811 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21854 TAF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37804 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5514 HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.593414 DLX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61451 BRD-K48263613 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01284 UFSP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0164 TIMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22898 hsa-miR-1295 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.885094 LN319 DepMap CRISPR Gene Dependency 1.0 3.2361 DBH_KO_GDS4324_362_mouse_Embryonic heart E10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SRF_KO_GDS3732_148_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-378f TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Hoxa13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.7095 Parabrachial nucleus, lateral division, ventral lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22639 signaling receptor activity GO Molecular Function Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABHD14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49069 Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.45867 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865026 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01727 Respiratory mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.487 GSE154074_1_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Supratrigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51181 hsa-miR-378b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.6483 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.4128 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2655 BRD-K22748970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09458 BRD-K31898235 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00997 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -1.83415 BRD-K79982586 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03096 posterodorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04364 CEP97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94155 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE153124_4_v_3_dsg2_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K19168437 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.49067 Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.5 BRD-K32974773 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09351 MELK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56256 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91928 NAGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82989 SMG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12404 SIKE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73937 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.87433 ARL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29702 TGF-beta_OE_GDS2974_137_mouse_corneas GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K09975370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26604 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.55779 strychnine-hcl LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.2156 Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.7164 BRD-K10089296 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13719 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8109 NXF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.39718 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tacrolimus-378 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K10911459 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47829 intermediate stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17544 hsa-miR-384 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 FBXO31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.42641 BRD-K76922696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.15162 BRD-K68160857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51683 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82933 Olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.593 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6259 NOP56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16009 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.60877 liminal part of the r6 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0238 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.10991 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63597 UNC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00726 PYCARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34142 CKMT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88018 BRD-K59984972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0271 Mediodorsal nucleus of the thalamus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37064 NCIH1944 CCLE Cell Line Gene Expression Profiles 1.0 2.0774 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 89.2953 MM1S DepMap CRISPR Gene Dependency 1.0 2.23494 Ventral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55867 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5202 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48916 GSE201042_6_v_0_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE180800,GSE180801_0_v_5_tex10_mouse RummaGEO Gene Perturbation Signatures 1.0 null membrane LOCATE Curated Protein Localization Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EB2 CCLE Cell Line Gene Expression Profiles 1.0 1.70032 SAP30BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1577 BRD-K20501114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32682 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25287 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF7_KO_GDS2069_68_mouse_olfactory epithelia GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USH1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27093 BRD-K00717406 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.78077 GSE60367_2_v_1_cxcr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null pentamidine-639 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K90019187 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31421 KLC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14624 intermediate stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42532 BRD-K88812218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14218 RAVER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07952 BRD-K24109044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85498 HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Inferior colliculus, dorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18355 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GU-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Malaria GWAS Catalog SNP-Phenotype Associations 2025 1.0 6.83979 BRD-A84913188 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4454 TIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21922 FRS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69708 BRD-K72707702 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.31037 BRD-K15940471 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03275 CPNE7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11471 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55886 BRD-K46913557 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07449 icSARS CoV_7Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.39566 RPS29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11552 CD8+_Tcells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.00123 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ISLR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05797 TRIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48413 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12896 BRD-K26231789 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14964 TRAPPC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16033 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAP3K1_knockout_245_GSE39240 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.64656 BRD-K95192796 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27752 WDR26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30413 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1529 intermediate stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07151 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.5643 MOTN1 CCLE Cell Line Gene CNV Profiles -1.0 -1.39258 PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Kidney_GSE9493_GENE_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K36644177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.27208 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.5 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.5856 trichlormethiazide-4198 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K23669327 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00468 ETV7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3394 HR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44774 BRD-K41731186 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16422 CCNI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08219 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K42976515 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63797 BRD-K76899562 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24622 KCNQ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40428 SNU668 CCLE Cell Line Gene Expression Profiles -1.0 -2.67457 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0942 UBE2D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56962 r2 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5798 BRD-A93436351 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.2666 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.3202 r11 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12331 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CEBPD_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLDN18_KO_GSE48443_44_mouse_lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K40485332 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04647 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K23553911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68583 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05978 CREB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94741 BRD-K65729622 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23481 tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50565 DUSP26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56904 Parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04045 cell part GO Cellular Component Annotations 2015 1.0 null TXNL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34297 BRD-K84514454 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.63313 ALG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58974 DHX35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33009 SUZ12 ENCODE Transcription Factor Targets 1.0 null Sensory Perception Reactome Pathways 2024 1.0 null IGROV1 CCLE Cell Line Gene Expression Profiles 1.0 2.10036 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5076 BRD-K93866368 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01708 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.3985 VIRMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2249 CIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75025 NHLRC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74806 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.3281 TINF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25338 Spinal nucleus of the trigeminal, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40893 KLF15_KO_GDS4780_509_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12842 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4454 MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sensory perception of chemical stimulus GO Biological Process Annotations 2023 1.0 null CCNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82664 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11347 GTPBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21053 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.56336 LXF-289 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.861587 NCIH716 DepMap CRISPR Gene Dependency 1.0 3.7336 retrotrapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9722 upper basal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06111 HCC515 DepMap CRISPR Gene Dependency 1.0 5.64973 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3329 BRD-K34209560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.35404 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.75405 PABPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05356 RPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92319 GSE164494_1_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GPCR downstream signaling Reactome Pathways 2014 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59914 BRD-A88691416 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79748 OVISE DepMap CRISPR Gene Dependency 1.0 2.09696 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.989 Kidney Chromophobe_KICH_TCGA-KO-8416-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K04559718 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0049 GSE87404,GSE87812_1_v_3_hoxa9_mouse RummaGEO Gene Perturbation Signatures -1.0 null nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8044 KBTBD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60327 mantle zone of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28696 BRD-K61315077 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.94518 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12951 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null ZNF283 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89218 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K35943892 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05112 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prosomere 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23644 g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null GANAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22685 Arid5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.216 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.981283 CCDC86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22626 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43N-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null S117 CCLE Cell Line Gene Expression Profiles 1.0 2.31004 r2 part of the ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00746 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K45237033 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.14867 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958179 BRD-K96663576 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.174 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.6048 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7858 MLX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04039 CEBPB_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A86977540 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10288 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A894-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9984 HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7108 DENND4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1622 PRSS22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11346 intermediate stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07151 Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCA1_Knock-in_GDS3544_562_mouse_Cerebellum - 12 Weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0183 Anterior cingulate area, dorsal part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12733 EXOC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04491 HDQ-P1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE148066,GSE157787_8_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE62843,GSE64370_0_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLCD3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96082 BRD-K64902833 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55782 BRD-K81261525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65306 STUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44342 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.829737 U20S BioGPS Cell Line Gene Expression Profiles 1.0 1.89611 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2574 PAX5_OE_GDS4978_548_human_L428-PAX5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K48129913 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.66227 DDIT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85491 HCC56 CCLE Cell Line Gene Expression Profiles -1.0 -1.45258 MRPL28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6369 BRD-K73899643 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32483 PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K02833343 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23041 MRPL24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92579 BT-549 GDSC Cell Line Gene Expression Profiles -1.0 -1.63653 CERS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38112 BRD-K03861440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35836 WEE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31799 Succinate dehydrogenase complex (ubiquinone) COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.612 PNRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19149 SHCBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.66041 r3 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02723 RNF126 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.11025 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13077 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10701 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943745 GSE201042_2_v_3_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taste bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.81 Sarcoma_SARC_TCGA-DX-A1L4-01A-12R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4723-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3 Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23135 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -1.69254 496100609_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.21818 TMEM147 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32522 DBH_KO_GSE33906_53_mouse_heart (E10.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3524 SYK_druginhibition_152_GSE34176 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.57708 DHRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57083 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49024 P4HTM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35679 BRD-K88996418 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58886 cii3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.961 Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00746 Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.920956 BRD-K26620362 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18958 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5224 NBN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06686 ODAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86476 Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.19691 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.5867 GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null core part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31035 SPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26462 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VCX3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50396 PGC-1alpha_Deficiency_GDS4904_310_mouse_Aged gastrocnemius muscle - 10 weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null UFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34293 Lung adenocarcinoma_LUAD_TCGA-MP-A4T4-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5624-01A-01R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pallidum, dorsal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90776 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30447 layer 3 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04757 BRD-K57472585 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57793 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null trovafloxacin_homo sapiens_gpl96_gse9166 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null cellular_component LOCATE Curated Protein Localization Annotations 1.0 null GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K16525290 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57625 External cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00746 r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12076 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2655 BRD-K14431723 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24184 ATR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19742 ZNF385B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3692 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8630-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEP68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55034 BRD-K49932469 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00411 496100667_TCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.11912 C15orf39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00018 Peripheral motor neuropathy_Sciatic Nerve_GSE1947 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.03666 okt8 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.15 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE164494_1_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K99827210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.33113 Lung adenocarcinoma_LUAD_TCGA-55-6983-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C14orf28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37053 BRD-K30842998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24936 MAP1LC3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91957 Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLCD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27113 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11475 Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1655 primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06079 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958179 GSE224547_1_v_0_cftr_human RummaGEO Gene Perturbation Signatures -1.0 null UQCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50043 BPTF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17258 OPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47038 medial amygdala, anterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10416 APOBEC3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13826 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HSC3 CCLE Cell Line Gene Expression Profiles 1.0 1.78605 Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K98876398 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84909 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K07781811 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.29188 Acute Lung Injury_Whole blood_GSE10474 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.61765 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3925-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null genistein-638 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.999646 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.813305 BRD-K09720842 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.86947 BRD-K02630367 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03024 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.910603 OUMS23 DepMap CRISPR Gene Dependency 1.0 2.71701 AMOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68714 WASF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73168 BRD-K61934967 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09862 FLII CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56494 NXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36633 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02291 BRD-K53748177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59154 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE201042_6_v_4_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null XAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62171 BRD-K43375231 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34538 BRD-K64722080 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04955 superficial stratum of r4BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23535 central part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.18435 BRD-K78886448 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.57481 RHOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14024 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52567 Fra-1_KO_GDS5078_402_mouse_Lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.11609 BRD-K50146114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.74618 TMEM169 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88272 LN443 CCLE Cell Line Gene CNV Profiles 1.0 1.33708 BRD-K14723547 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79929 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74123 BRD-K44078665 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.86986 ARHGAP45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42261 BRD-K03765511 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72034 Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35421 CHP-134 GDSC Cell Line Gene Expression Profiles 1.0 1.74542 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 BRD-K99380757 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3797 LS1034 DepMap CRISPR Gene Dependency 1.0 2.63578 Sarcoma_SARC_TCGA-X6-A8C2-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25646 olfactory receptor activity GO Molecular Function Annotations 2023 1.0 null HNF4A ENCODE Transcription Factor Targets 1.0 null GSE201042_2_v_1_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TNNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6236 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00814 hii3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.626 HT CCLE Cell Line Gene Expression Profiles 1.0 1.44845 signal transducer activity GO Molecular Function Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GF-A769-01A-32R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03663 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4074 intermediate stratum of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26247 intermediate gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20634 BRD-K33497830 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22057 NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.68303 CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSC1 DepMap CRISPR Gene Dependency 1.0 2.28512 PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null MBTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93107 SULT2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65923 BRD-A48478073 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07413 DCTN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68075 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.918706 GSE239541_11_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0198 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-4279 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MM383 DepMap CRISPR Gene Dependency 1.0 4.35488 r1 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26247 Acute Myeloid Leukemia_LAML_TCGA-AB-3006-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08663 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958179 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36284 layer 2 of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26365 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K77591784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80714 intermediate stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37156 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.99614 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03061 COV318 CCLE Cell Line Gene CNV Profiles -1.0 -1.46637 CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.93865 S-isopropylisothiourea LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07677 BRD-K72161690 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81713 HMGCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88413 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02663 JARID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32952 MDAMB361 CCLE Cell Line Gene CNV Profiles -1.0 -2.34303 BRD-A75087829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32485 SDF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42023 WTIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53733 SPOUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38274 BGC823 CCLE Cell Line Gene CNV Profiles 1.0 1.33708 AGPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52159 integral component of membrane GO Cellular Component Annotations 2015 1.0 null VOPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23298 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5276-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76011 regulation of biological process GO Biological Process Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68092 Kidney Chromophobe_KICH_TCGA-KL-8343-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.0954 RAD9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27453 BUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01331 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K56470219 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -6.20693 BRD-K21367867 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84049 ANKIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07576 NAMALWA CCLE Cell Line Gene Expression Profiles -1.0 -2.12956 LPS6 DepMap CRISPR Gene Dependency 1.0 3.32144 pipenzolate LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22499 CSPG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05001 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VG-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K74314059 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79848 UMUC14 DepMap CRISPR Gene Dependency 1.0 5.73631 DCUN1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16985 BRD-K01894374 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79422 primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.915081 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48916 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8374 PXDNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4527 M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null ICC4 DepMap CRISPR Gene Dependency 1.0 2.02125 Cardiac Failure_Myocardial tissue_GSE1988 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -3.1308 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.41641 BRD-K59870481 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10075 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959694 GSE240444_2_v_3_idasanutlin_human RummaGEO Drug Perturbation Signatures 1.0 null CEBPB_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Large cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.873 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 trastuzumab_homo sapiens_gpl570_gse15043 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K81665173 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39415 olfactory receptor activity GO Molecular Function Annotations 2025 1.0 null Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 62.3089 posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.932931 BRD-K56075657 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40723 HSF1_KD_GDS1733_754_human_HeLa cells - 0 Hour by siHSF1_2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.858376 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.43061 p2 part of the zona limitans core population Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72728 r2 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20844 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I1-06A-12R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRSS27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43002 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null liminal part of r2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06805 PSMA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60098 dosulepin-1713 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25661 NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.24853 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5429 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7924 ARHGEF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30083 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Z-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A4PQ-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KIAA1671 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73023 SIAH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56138 MYC-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null bladder GTEx Tissue Gene Expression Profiles 1.0 0.874647 Lung adenocarcinoma_LUAD_TCGA-50-6593-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K90527476 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.58013 VCY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52806 BRD-K71005143 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32464 NCI-H2228 GDSC Cell Line Gene Expression Profiles -1.0 -1.598 NCIH2227 CCLE Cell Line Gene CNV Profiles 1.0 1.94047 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13667 SHH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.52199 FAM86B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00777 Uvula (IX), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0139 AFTPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99976 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.858 BRD-K93337444 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85446 neurological system process GO Biological Process Annotations 2015 1.0 null S1PR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89135 interstitial nucleus of the zona limitans Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17544 NCIH1650 CCLE Cell Line Gene CNV Profiles -1.0 -1.63985 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K76154866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03781 mantle zone of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06805 DLD-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877177 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959694 LIG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68769 H4K20me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.914567 BRD-K68330990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84203 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 94.9191 BRD-K08938154 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05375 olfactory receptor activity GO Molecular Function Annotations 2015 1.0 null TEKT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0393 HSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38398 ZNHIT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2455 sensory perception of smell GO Biological Process Annotations 2015 1.0 null CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.66877 IPO7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99898 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5399-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K55053106 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.12419 hsa-miR-4747-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSTCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44078 ZNF500 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01338 PABPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93199 HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.74085 MOCS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43707 A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.78033 BRD-K92059157 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73081 detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null BRD-K47238978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17616 Arteriosclerotic cardiovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.134 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.4078 BRD-K10989739 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2055 Thalamus, sensory-motor cortex related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19797 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32213 Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GPATCH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32921 TE-11 GDSC Cell Line Gene Expression Profiles 1.0 2.86466 GSE160304,GSE163392_7_v_3_zswim8_human RummaGEO Gene Perturbation Signatures 1.0 null DLGAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16319 Breast Cancer_Mammary Gland Tissue_GSE3744 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.82326 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Supraspliceosomal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.069 BRD-K34335352 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47088 FBXW9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64366 HEXD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34221 GSE126001_3_v_0_il13_mouse RummaGEO Gene Perturbation Signatures -1.0 null Linear nucleus of the medulla Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04748 496100560_PCx_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01035 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null Chorionic epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.807 WB-4101 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09721 PCM6 CCLE Cell Line Gene Expression Profiles -1.0 -1.63486 TPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19031 plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null SDCBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43733 EIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.44772 B4GALT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36842 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.521 sanguinarine-4168 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SKNFI DepMap CRISPR Gene Dependency 1.0 2.27228 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 NCIH1355 CCLE Cell Line Gene Expression Profiles 1.0 2.90798 SPIB JASPAR Predicted Transcription Factor Targets 1.0 null RPL18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55627 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39464 H3K27me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K13225050 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.17068 OVCAR3 BioGPS Cell Line Gene Expression Profiles -1.0 -1.26024 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.6613 NOVA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49936 GPKOW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03336 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null lateral superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0139 Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K47471281 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45789 sensory perception of chemical stimulus GO Biological Process Annotations 2015 1.0 null medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35568 BRD-K21215763 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52404 receptor activity GO Molecular Function Annotations 2015 1.0 null SLC25A32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01067 PIK3R4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99065 DENND6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52152 Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.56504 Signaling by GPCR Reactome Pathways 2014 1.0 null FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.2979 membrane part GO Cellular Component Annotations 2015 1.0 null BRD-K36445086 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15043 CLDN18_KO_GDS4961_28_mouse_whole lung tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-376a TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865026 GR MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K76588804 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.72074 GSE217694_3_v_2_pold1_mouse RummaGEO Gene Perturbation Signatures 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null NP8 DepMap CRISPR Gene Dependency 1.0 2.12477 superficial stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1671 Superior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.50167 ZNF200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67695 BRD-K61087440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.59323 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IT-01A-31R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K80495774 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17552 CTSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2812 layer 3 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5621 DPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98231 Brain Lower Grade Glioma_LGG_TCGA-FG-8186-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r4 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07151 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46235 COX7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97754 CENPVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80226 Lateral terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95239 GSE155852_0_v_2_apigenin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27224 PRRC2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81937 CENPJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62373 FGD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96266 BRD-K10704442 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.17731 EIF1AD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13206 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25039 ALG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.551 CRLF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68542 Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CADM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59539 tetraethylenepentamine-405 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null UBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95242 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.975034 BRD-K78337983 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05057 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22103 BRD-K94385157 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00499 SNCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25335 SENP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65743 BRD-K19527338 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15019 Respiratory smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.209 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DENND4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22285 MIS18BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08338 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32 lateral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12682 Hepatoblastoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.045 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null isopropamide iodide-2720 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5115-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70377 BRD-K11105500 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02009 NSMCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74991 Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K87794979 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22104 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 114.687 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.847194 SPRYD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.43304 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4268 GSE217694_4_v_0_pold1_mouse RummaGEO Gene Perturbation Signatures -1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null BRD-K22390389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.22053 ZNF599 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81054 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RA-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6651 CDC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71318 PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18 Rummagene Transcription Factor Associations 2026 1.0 null ARID4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81512 LP1 DepMap CRISPR Gene Dependency 1.0 3.03851 GSE201042_6_v_7_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K98140933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21725 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2021 NCIH292 DepMap CRISPR Gene Dependency 1.0 2.16841 RPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01539 SCABER COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7281-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ASB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43285 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65873 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958179 ARF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70333 CIB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24932 BRD-K02061146 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18267 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 77.3704 TRNAU1AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62095 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9837 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07016 BRD-K17420784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05421 prethalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59201 Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06868 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0967 BRD-K83751422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32531 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.05021 BRD-K18763924 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.02252 C1QTNF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11693 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06209 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K61134709 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6456 GSE147056_3_v_1_actl6b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Globus pallidus, internal segment Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33856 RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8754 SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.969642 MDAMB436 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.11371 CYSRT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53232 BRD-K43298189 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.389 SEC24D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.74631 STMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17274 Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46343 BRD-K96575636 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10698 NCIH2286 CCLE Cell Line Gene CNV Profiles 1.0 1.3785 Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30056 BRD-K09432998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.112 hippocampus (hippocampal formation)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23202 CKAP2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28762 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.4031 dorsal periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.61086 RH30 CCLE Cell Line Gene Expression Profiles -1.0 -1.61473 TP63 ChEA Transcription Factor Targets 1.0 null clidinium LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25833 EBF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92505 Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877177 hsa-miR-378d TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 SLVL DepMap CRISPR Gene Dependency 1.0 2.14024 BRD-K76892938 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23432 BRD-K08715020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.98638 ASPHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71673 WASHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38145 ZFAND6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18729 BRD-K69854611 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27747 GADD45B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09926 Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86257 mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09061 SJSA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49978 BRD-K02638906 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06799 BRD-K99125195 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10441 layer 6 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11146 UCKL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16391 superficial gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19935 reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.27175 Lung adenocarcinoma_LUAD_TCGA-55-7227-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A89947015 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.07045 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8579 MRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01965 Spleen-plasma cell Tabula Sapiens Gene-Cell Associations 1.0 6.11911 Brain Lower Grade Glioma_LGG_TCGA-HT-7470-01A-12R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRKACA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33848 GATA3-26560356-CHIP-SEQ-TH1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.47036 SMNDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21312 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03462 GSE189859,GSE189861_0_v_2_idh1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mediodorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13815 NCI-H510A GDSC Cell Line Gene Expression Profiles 1.0 1.43262 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.948639 hsa-miR-3654 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.7399 APC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26958 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83541 Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07526 CARD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96164 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null Parasubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37777 Cystic Fibrosis_Intestinal Epithelium_GSE765 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.12662 YPEL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05337 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8772 Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.37229 COLO-741 COSMIC Cell Line Gene Mutation Profiles 1.0 null INO80D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.8635 BRD-K93040255 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3291 AEBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81424 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K89000000 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6107 BRD-K76900919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57413 GSE157960_2_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null COG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76901 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924963 NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2026 CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null ventral nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10291 GNG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03775 AKT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86097 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57527 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5626 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 76.0642 SNRPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23911 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WN-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K60287661 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.743 BRD-K07489055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.89741 Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9739 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47702 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A642-01A-12R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44685 BRD-A24369193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19272 PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2 Rummagene Transcription Factor Associations 2026 1.0 null drofenine-2714 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PANK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87243 hsa-miR-3158-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1003 BRD-K96120749 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.93267 BRD-K51253991 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62178 mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16031 Brn3a_KO_GDS1651_247_mouse_Embryonic (day 13.5) trigeminal ganglia - heterozygous GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null r3 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1308 GSE62843,GSE64371_2_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K83270266 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07657 BRD-K78647367 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32858 RPL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43754 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4810-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K56562541 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01792 BRD-A82843133 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.7655 Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLHL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54109 cellular_component GO Cellular Component Annotations 2015 1.0 null ACHE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05607 Globus pallidus, external segment Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02763 Superior olivary complex, periolivary region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.47036 TAB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08256 HCC193 Klijn et al., Nat. 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