association dataset threshold value standardized value SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34696 Perturb_9852_KD_LUC7L_ERP124746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.72228 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6164 KATOIII CCLE Cell Line Gene CNV Profiles 1.0 1.63623 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040633 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6279 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.3532 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.910474 Olfactory Signaling Pathway Reactome Pathways 2014 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08423 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44586 Six3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.5809 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.21214 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2071 TFEB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8523 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24454 outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.832759 SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36986 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.1046 Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.6941 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5124 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.5576 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1495 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.6452 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00818 locus ceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13216 NCIH526 CCLE Cell Line Gene CNV Profiles 1.0 2.24628 SW837 CCLE Cell Line Gene CNV Profiles 1.0 1.38762 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65366 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87468 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18734 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13326 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS-68 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.887 GSE187006_0_v_1_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 54.9259 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5923 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3359-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Elf5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.5563 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9924 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.7521 GSE176008_7_v_1_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0986 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4034 SCLC22H DepMap CRISPR Gene Dependency 1.0 2.72384 CTB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1395 DepMap CRISPR Gene Dependency 1.0 2.5472 cellular_component GO Cellular Component Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00993 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5689 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08549 TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9091 outer CP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21192 NCI-H1651 COSMIC Cell Line Gene Mutation Profiles 1.0 null HT COSMIC Cell Line Gene Mutation Profiles 1.0 null PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.732 RPS20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51368 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.736 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64363 Lhx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.5791 HT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09377 Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.68444 SUDHL5 CCLE Cell Line Gene CNV Profiles -1.0 -1.33091 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16177 Foreskin fibroblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.623 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39289 KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00818 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33742 cell part LOCATE Predicted Protein Localization Annotations 1.0 null molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58524 MIER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35569 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.0292 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.96 G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835817 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11885 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.518573 Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE203329_0_v_1_mettl5_human RummaGEO Gene Perturbation Signatures -1.0 null SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21746 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6211 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0702 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07377 SOX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26238 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.7751 HT-144 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.8837 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21239 496100498_PCx_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.61452 IGR39 DepMap CRISPR Gene Dependency 1.0 2.32279 LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8571 PMC6440742-elife-43627-supp4.xlsx-NFE2L2_ChIP-HeLa_ChIP1_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null signaling receptor activity GO Molecular Function Annotations 2015 1.0 null molecular transducer activity GO Molecular Function Annotations 2015 1.0 null NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04629 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null plasma membrane part GO Cellular Component Annotations 2015 1.0 null CCFSTTG1 DepMap CRISPR Gene Dependency 1.0 2.52972 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8147 Arid5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 51.2391 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NI-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07617 5g3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.156 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9702 THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 76.317 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52556 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63452 WM88 CCLE Cell Line Gene CNV Profiles -1.0 -2.25935 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6697 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66399 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 102.433 NCIH196 CCLE Cell Line Gene CNV Profiles -1.0 -1.99458 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.18096 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3362-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100439_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.24369 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7948 Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HQ-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01392 U266B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.67451 regulation of cellular process GO Biological Process Annotations 2015 1.0 null SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0433 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1195 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.1154 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3632 detection of chemical stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5566-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.9442 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 43.8781 EZH2 ENCODE Transcription Factor Targets 1.0 null TFAP2A-17053090-MCF7-human ChEA Transcription Factor Binding Site Profiles 1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.00961 ICC4 DepMap CRISPR Gene Dependency 1.0 3.11962 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.866315 SUIT-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.826591 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9848 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969649 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain capillary endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.621 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1495 sf-21 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.44085 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25981 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.5558 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2744 SMAD5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0098 496100549_FWM_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00948 T3M5 DepMap CRISPR Gene Dependency 1.0 2.18507 Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.3347 MEIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9126 Hoxa13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 75.2098 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.2288 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28958 VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33198 LXF289 DepMap CRISPR Gene Dependency 1.0 2.9491 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837665 layer I of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853023 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.983 NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 1.78663 NCIH2073 CCLE Cell Line Gene CNV Profiles -1.0 -1.79969 sensory perception of chemical stimulus GO Biological Process Annotations 2023 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877968 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061616 NCIH2087 DepMap CRISPR Gene Dependency 1.0 2.24826 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9854_KD_LUC7L3_ERP124746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.95483 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1326 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null SU-DHL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21612 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3741 JHH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sensory Perception Reactome Pathways 2024 1.0 null olfactory receptor activity GO Molecular Function Annotations 2023 1.0 null ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8214 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911304 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50967 SALL4_01_98 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60726 precentral gyrus, right, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51498 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21612 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65213 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050421 HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6138 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49549 Emphysema imaging phenotypes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.669897 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9864 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0176 BL70 DepMap CRISPR Gene Dependency 1.0 2.15729 KHM1B CCLE Cell Line Gene CNV Profiles 1.0 1.39733 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4768-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8589 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75774 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.828 Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 47.877 H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null sensory perception of smell GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911304 ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3604 TFAP2A ChEA Transcription Factor Targets 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1753 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.895542 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44692 KML1 DepMap CRISPR Gene Dependency 1.0 4.02743 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.04562 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49016 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.13875 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.8243 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06881 LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6529 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01097 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052793 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08423 Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.818 OCIAML3 DepMap CRISPR Gene Dependency 1.0 3.84533 Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.898853 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04523 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 CTCF ENCODE Transcription Factor Targets 1.0 null ACN COSMIC Cell Line Gene Mutation Profiles 1.0 null TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5666 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12481 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01097 Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25573 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00872 medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.859045 COLO678 CCLE Cell Line Gene CNV Profiles 1.0 1.492 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4920-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Umbilical vein endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.657 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040757 Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.1555 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8186 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 49.1875 Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.2783 PATU8902 CCLE Cell Line Gene CNV Profiles 1.0 1.34103 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902224 Olfactory transduction KEGG Pathways 2026 1.0 null CCNB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93669 gigantocellular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37423 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0873 496100657_FWM_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33545 neurological system process GO Biological Process Annotations 2015 1.0 null Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 62.1942 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9688 outer CP in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.911565 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02289 HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -3.21042 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7919 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868277 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane LOCATE Predicted Protein Localization Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null T47D CCLE Cell Line Gene CNV Profiles 1.0 2.1093 membrane GO Cellular Component Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-4532-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6992 superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.7456 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.492 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3541 HOP-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null HEL DepMap CRISPR Gene Dependency 1.0 6.31094 KYSE450 CCLE Cell Line Gene CNV Profiles -1.0 -1.95748 TFAP2A-17053090-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8296 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.1017 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0548 Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100360_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.15775 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.967164 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2892 HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 2.71799 detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2015 1.0 null MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1753 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054526 Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sox3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.8511 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.3188 Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4839-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2502 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849084 CARMIL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51432 Chronic wasting disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.008 PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53 Rummagene Transcription Factor Associations 2026 1.0 null nerve GTEx Tissue Gene Expression Profiles 1.0 1.04221 SMAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8835 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.8815 SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49096 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0622 SP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.859738 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6875 LCLC103H CCLE Cell Line Gene CNV Profiles -1.0 -2.07507 REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08863 CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875982 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 76.4815 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.4462 Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.788183 496100361_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.76821 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04537 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00293 VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03649 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837665 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NL-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3684 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.36263 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KP-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null SNU761 CCLE Cell Line Gene CNV Profiles -1.0 -2.02285 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS299 DepMap CRISPR Gene Dependency 1.0 2.39478 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.8515 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.215928 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08549 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3326-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26106 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40731 detection of stimulus GO Biological Process Annotations 2015 1.0 null MEWO CCLE Cell Line Gene CNV Profiles -1.0 -1.32791 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7031 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13474 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056151 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7349 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3877 Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5245 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69981 TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3284 Nobox JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.2105 NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.45755 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28213 LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7965 ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2843 ovary cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.081737 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.884442 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04179 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20213 inner SZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18332 Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.7934 NCI-H2373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00818 PSS008 DepMap CRISPR Gene Dependency 1.0 3.55339 NTERA2CLD1 DepMap CRISPR Gene Dependency 1.0 5.92598 Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB4 DepMap CRISPR Gene Dependency 1.0 3.49657 Carcinoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.653 PSN1 DepMap CRISPR Gene Dependency 1.0 2.42095 CACO2 CCLE Cell Line Gene CNV Profiles 1.0 1.36724 127399 DepMap CRISPR Gene Dependency 1.0 2.92403 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.926378 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8482 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03961 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1982 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SP-01A-31R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCILY10 CCLE Cell Line Gene CNV Profiles -1.0 -1.45574 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4945-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058464 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.90091 plasma membrane GO Cellular Component Annotations 2015 1.0 null 8MGBA DepMap CRISPR Gene Dependency 1.0 7.83725 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.2881 Umbilical vein endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.563 sensory perception of smell GO Biological Process Annotations 2025 1.0 null arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.74789 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.573898 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.676 LNCaP clone FGC TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.332 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SKMEL2 DepMap CRISPR Gene Dependency 1.0 2.90179 Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13474 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6838 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6597 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.39449 ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.99 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.613103 HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4244 MAFK ENCODE Transcription Factor Targets 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null ERCC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02729 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HD-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1769 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01457 MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5985 Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-6720-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO824 DepMap CRISPR Gene Dependency 1.0 3.08618 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE176008_7_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5727 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5143 EB-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21553 sensory perception of smell GO Biological Process Annotations 2023 1.0 null NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.55999 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.88563 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.952378 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5807 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8333 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12567 IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCIMY7 CCLE Cell Line Gene CNV Profiles 1.0 1.38009 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1753 SNU668 DepMap CRISPR Gene Dependency 1.0 2.10089 TCF21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5997 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.13659 sensory perception of chemical stimulus GO Biological Process Annotations 2015 1.0 null 496100598_PCx_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.34079 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5399-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 66.9318 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100435_TCx_probable Alzheimer's disease_TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 8.43505 cell part GO Cellular Component Annotations 2015 1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19707 LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40393 DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 regulation of biological process GO Biological Process Annotations 2015 1.0 null NCIH929 CCLE Cell Line Gene CNV Profiles 1.0 1.83032 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911304 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3602 Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.4497 intrinsic component of plasma membrane GO Cellular Component Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945633 frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28484 HCC366 CCLE Cell Line Gene CNV Profiles 1.0 2.08404 Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.4817 PANC-08-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.39904 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00818 Heschl's gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61863 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.4703 MAX::MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3333 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25981 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 9505BIK DepMap CRISPR Gene Dependency 1.0 2.59399 bladder GTEx Tissue Gene Expression Profiles 1.0 0.85201 IZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08504 TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.8966 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.338 OVOL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.03 GPCR downstream signaling Reactome Pathways 2014 1.0 null Lhx8 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.6044 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6878 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877968 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6220-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903966 RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15367 sensory perception GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EWS502 DepMap CRISPR Gene Dependency 1.0 2.39973 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.938725 SOX14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8539 BACH1 ENCODE Transcription Factor Targets 1.0 null Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0035 POLR2A ENCODE Transcription Factor Targets 1.0 null CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.92478 olfactory receptor activity GO Molecular Function Annotations 2025 1.0 null 496100447_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.32937 HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.583217 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5619 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.844752 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.892764 PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53 Rummagene Transcription Factor Associations 2026 1.0 null pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86686 binding GO Molecular Function Annotations 2015 1.0 null sensory perception of chemical stimulus GO Biological Process Annotations 2025 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26436 CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06881 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1869 IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.663 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.837625 NR1I2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0272 RPMI7951 DepMap CRISPR Gene Dependency 1.0 3.48972 principal sensory nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.904408 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42342 lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.927478 SK-MES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4072 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.2076 RT-112 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.9565 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04024 Sarcoma_SARC_TCGA-QQ-A8VF-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69399 MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.956341 PL18 COSMIC Cell Line Gene CNV Profiles -1.0 -3.24687 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4706 SKNAS CCLE Cell Line Gene CNV Profiles -1.0 -1.37797 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11927 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.871466 NCI-H727 COSMIC Cell Line Gene CNV Profiles 1.0 2.15316 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23518 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00945 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.921677 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XF-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ROR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53265 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.135 LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.843746 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60523 BACH1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null Creb5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.7562 GSE234514,GSE234516_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV5::HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.101 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9198 ovary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.402144 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25886 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55046 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9731 PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1629 SOX2-21211035-LN229-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HARA CCLE Cell Line Gene CNV Profiles 1.0 2.79429 cingulate gyrus, parietal part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0459 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.81082 Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.5924 ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2138 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ME1 CCLE Cell Line Gene CNV Profiles 1.0 2.00004 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64363 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.790172 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8682 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4987-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null signal transduction GO Biological Process Annotations 2015 1.0 null superior temporal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36269 FOXH1-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RH30 DepMap CRISPR Gene Dependency 1.0 2.4985 OS252 DepMap CRISPR Gene Dependency 1.0 5.62846 NCIH727 CCLE Cell Line Gene CNV Profiles 1.0 1.46324 membrane part GO Cellular Component Annotations 2015 1.0 null NCIH1573 CCLE Cell Line Gene CNV Profiles 1.0 1.72345 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RH28 DepMap CRISPR Gene Dependency 1.0 2.37847 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6203 RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3945 496100424_FWM_probable Alzheimer's disease_TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16206 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25719 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1891 HT-29 COSMIC Cell Line Gene Mutation Profiles 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.79489 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03574 sf-9 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.13368 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7841 MDAMB134VI CCLE Cell Line Gene CNV Profiles -1.0 -1.47146 496100486_PCx_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.17041 TNFSF13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69167 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9234 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68511 RDES CCLE Cell Line Gene CNV Profiles 1.0 1.37393 WM88 DepMap CRISPR Gene Dependency 1.0 3.54774 deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.882289 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4164 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5120-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1954 DepMap CRISPR Gene Dependency 1.0 3.93314 Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.5789 PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53 Rummagene Transcription Factor Associations 2026 1.0 null NCIH2110 CCLE Cell Line Gene CNV Profiles -1.0 -1.66929 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 62.0667 NCI-H1436 COSMIC Cell Line Gene Mutation Profiles 1.0 null ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1311 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25719 KMS21BM CCLE Cell Line Gene CNV Profiles 1.0 1.64552 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04478 Alx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.1333 LN319 DepMap CRISPR Gene Dependency 1.0 3.22663 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32047 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NL-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE154936_3_v_2_remdesivir_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2859 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5835 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.930631 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.18361 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 68.25 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.78724 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050495 PGA1 DepMap CRISPR Gene Dependency 1.0 2.1631 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7407 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.64367 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40571 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C2BBE1 CCLE Cell Line Gene CNV Profiles 1.0 1.35147 Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.8779 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.997457 WM115 DepMap CRISPR Gene Dependency 1.0 3.71647 system process GO Biological Process Annotations 2015 1.0 null ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4521 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.78284 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 104.342 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1462 CL-34 COSMIC Cell Line Gene Mutation Profiles 1.0 null SUIT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3304 Brain Lower Grade Glioma_LGG_TCGA-F6-A8O4-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U87MG DepMap CRISPR Gene Dependency 1.0 3.00272 multicellular organismal process GO Biological Process Annotations 2015 1.0 null RUNX1_01_47 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.99667 SU-DHL-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849588 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888561 Lhx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.2621 Adenocarcinoma stem-like cell_Lung_Human CellMarker Gene-Cell Type Associations 1.0 null retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.999648 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08549 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.30697 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.1502 biological_process GO Biological Process Annotations 2015 1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00279 NCIH727 DepMap CRISPR Gene Dependency 1.0 2.16983 precuneus, right, inferior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20216 KE39 CCLE Cell Line Gene CNV Profiles 1.0 1.77957 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1423 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21951 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39594 ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9347 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5609 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null olfactory receptor activity GO Molecular Function Annotations 2015 1.0 null NCI-H660 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969649 Lung adenocarcinoma_LUAD_TCGA-86-A456-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PA-TU-8902 COSMIC Cell Line Gene Mutation Profiles 1.0 null Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 53.1007 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.06796 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16808 496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.29302 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.970018 GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0398 H2AFZ ENCODE Transcription Factor Targets 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39824 Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.5242 496100556_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.59638 SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.606 HEL CCLE Cell Line Gene CNV Profiles 1.0 2.00133 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.307 KP-N-YN COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW948 DepMap CRISPR Gene Dependency 1.0 4.94521 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVSAHO CCLE Cell Line Gene CNV Profiles -1.0 -1.92182 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050495 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25704 Brain Lower Grade Glioma_LGG_TCGA-R8-A6ML-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.1751 biological regulation GO Biological Process Annotations 2015 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0928 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1824 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.7671 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75782 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93328 Olfactory receptor InterPro Predicted Protein Domain Annotations 1.0 null PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null WSU-NHL COSMIC Cell Line Gene Mutation Profiles 1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.99572 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GS-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF479 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9709 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09549 dorsal motor nucleus of the vagus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0005 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01384 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.08858 SKBR3 DepMap CRISPR Gene Dependency 1.0 5.06424 g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null KMS34 DepMap CRISPR Gene Dependency 1.0 6.99516 Olfactory Signaling Pathway Reactome Pathways 2024 1.0 null NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03531 Foxf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.79 Actin wave COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.425 BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0604 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3888 TC71 DepMap CRISPR Gene Dependency 1.0 6.37235 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.93348 Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.015 SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.936571 KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30247 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.956092 g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2836 HT CCLE Cell Line Gene CNV Profiles -1.0 -1.63122 GP5D DepMap CRISPR Gene Dependency 1.0 3.2098 NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.61292 Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.2969 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7840-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF1 ENCODE Transcription Factor Targets 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.90091 MAFK_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0767 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04537 NCIH841 DepMap CRISPR Gene Dependency 1.0 2.20973 MAFF ENCODE Transcription Factor Targets 1.0 null CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.665 YAPC CCLE Cell Line Gene CNV Profiles 1.0 1.4205 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.897105 SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.62615 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.976087 odorant binding GO Molecular Function Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACAD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69093 496100650_TCx_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.1181 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null WM983B CCLE Cell Line Gene CNV Profiles -1.0 -2.57412 Signal Transduction Reactome Pathways 2014 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04629 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0336 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE4 CCLE Cell Line Gene CNV Profiles -1.0 -1.45856 signal transducer activity GO Molecular Function Annotations 2015 1.0 null layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05072 integral component of membrane GO Cellular Component Annotations 2015 1.0 null Skmes TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.268 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.2269 PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2784 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.888 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9989 response to stimulus GO Biological Process Annotations 2015 1.0 null TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.7736 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46022 SKMM2 CCLE Cell Line Gene CNV Profiles 1.0 1.33033 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4104 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.4812 CAS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.4828 MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4978 CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.41379 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01097 HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8548 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55669 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1036 integral component of plasma membrane GO Cellular Component Annotations 2015 1.0 null lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860942 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14238 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34106 Expression and translocation of olfactory receptors Reactome Pathways 2024 1.0 null inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06347 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0618 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2855 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.9463 receptor activity GO Molecular Function Annotations 2015 1.0 null HT1197 DepMap CRISPR Gene Dependency 1.0 2.47676 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04629 temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33765 molecular_function GO Molecular Function Annotations 2015 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.936331 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849588 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.6476 supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03742 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837665 CHP126 CCLE Cell Line Gene CNV Profiles -1.0 -1.60598 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.01771 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12481 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.8088 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71293 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25573 Signaling by GPCR Reactome Pathways 2014 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.04065 U2904 DepMap CRISPR Gene Dependency 1.0 4.51353 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945633 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.90091 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8518 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.42567 ncih727 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.078 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.8608 MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2078 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60447 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 57.6395 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0172 RL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972967 outer CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870376 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53137 SNU886 CCLE Cell Line Gene CNV Profiles -1.0 -1.65163 PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9 Rummagene Transcription Factor Associations 2026 1.0 null SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.97183 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 64.4009 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 76.767 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849588 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.43454 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.261 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44891 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849084 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1753 stratum pyramidale of rostral CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.12678 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB12 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.968634 detection of chemical stimulus GO Biological Process Annotations 2015 1.0 null transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.12937 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971928 CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.953593 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19052 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9354 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 58.9242 496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.83524 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20158 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22424 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838605 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05381 SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null cervix uteri GTEx Tissue Gene Expression Profiles 1.0 1.19867