association dataset threshold value standardized value G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null inner CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.982442 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7631 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-01A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29779 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9891 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.914082 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23698 Specific language impairment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.671 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0013 ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7752 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.4167 G59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40472 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dyscalculia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.785 single-organism process GO Biological Process Annotations 2015 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.982523 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.88755 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02856 HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5598 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05546 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.889398 NCI-H1395 COSMIC Cell Line Gene CNV Profiles 1.0 2.10038 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8687 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0669 GATA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.051 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33459 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.5043 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.374 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12208 BT12 DepMap CRISPR Gene Dependency 1.0 6.52386 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6976 IST-SL1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.8511 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928191 multicellular organismal process GO Biological Process Annotations 2015 1.0 null UMUC11 DepMap CRISPR Gene Dependency 1.0 3.8215 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08439 KYSE30 CCLE Cell Line Gene CNV Profiles 1.0 1.57782 system process GO Biological Process Annotations 2015 1.0 null outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.842468 integral component of plasma membrane GO Cellular Component Annotations 2015 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55826 regulation of cellular process GO Biological Process Annotations 2015 1.0 null BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.38018 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43199 CTCF ENCODE Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null detection of chemical stimulus involved in sensory perception of smell GO Biological Process Annotations 2015 1.0 null Olfactory Signaling Pathway Reactome Pathways 2014 1.0 null Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1659 SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08916 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4665 UBLC1 DepMap CRISPR Gene Dependency 1.0 5.57877 Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90696 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07117 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23055 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3667 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.33342 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8449 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41307 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06204 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.0297 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.860241 WM1799 CCLE Cell Line Gene CNV Profiles 1.0 1.51706 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.5182 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3692 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9235 MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.72452 integral component of membrane GO Cellular Component Annotations 2015 1.0 null CFPAC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.38316 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9302 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.2783 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.856897 UMUC10 DepMap CRISPR Gene Dependency 1.0 2.32244 intrinsic component of plasma membrane GO Cellular Component Annotations 2015 1.0 null SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65372 Olfactory Signaling Pathway Reactome Pathways 2024 1.0 null CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09656 HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1089 CEBPB ENCODE Transcription Factor Targets 1.0 null BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4456 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08374 JHH5 CCLE Cell Line Gene CNV Profiles 1.0 1.55086 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8519 hippocampus (hippocampal formation)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.57287 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4968-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9024 H3K27me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOMO-1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.199 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6837 detection of chemical stimulus GO Biological Process Annotations 2015 1.0 null NZM42 DepMap CRISPR Gene Dependency 1.0 2.87656 SNU1033 CCLE Cell Line Gene CNV Profiles 1.0 1.98776 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00023 Mitral cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.11 ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90696 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.2816 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.77499 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 LU-99A COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE175787_5_v_7_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null SNU475 DepMap CRISPR Gene Dependency 1.0 5.27802 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15024 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0907 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.38882 STAT6_01_50 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.32535 496100384_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 17.4817 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.7978 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.849036 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.963124 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.104 ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3472 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4899 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.93996 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14371 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2372 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9714 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6047 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 106.167 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9229 NCIH3255 CCLE Cell Line Gene CNV Profiles 1.0 1.45587 DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.04343 amygdaloid complex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00268 KU1919 CCLE Cell Line Gene CNV Profiles -1.0 -1.42865 Arid5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.5615 Olfactory receptor InterPro Predicted Protein Domain Annotations 1.0 null SUM102PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.843794 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.589 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0358 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22322 Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.6694 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.60877 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.851791 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22141 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03931 Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SKMEL28 CCLE Cell Line Gene CNV Profiles -1.0 -1.66768 HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0875 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0997 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.336 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8858 GSE112202_5_v_2_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.885018 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.996549 SNU475 CCLE Cell Line Gene CNV Profiles 1.0 2.26999 IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4067 membrane part GO Cellular Component Annotations 2015 1.0 null PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53 Rummagene Transcription Factor Associations 2026 1.0 null HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.53637 KYSE410 DepMap CRISPR Gene Dependency 1.0 4.33007 HCC461 DepMap CRISPR Gene Dependency 1.0 2.76954 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15024 outer CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.930819 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Mitral cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.059 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.24993 SMSCTR DepMap CRISPR Gene Dependency 1.0 2.57522 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.277 LB2518-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72491 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.1438 NCI-H1770 COSMIC Cell Line Gene Mutation Profiles 1.0 null odorant binding GO Molecular Function Annotations 2015 1.0 null STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OE21 CCLE Cell Line Gene CNV Profiles 1.0 1.67605 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.5014 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2836 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71242 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.5934 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.855401 RPMI-7951 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14235 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945405 SKMEL2 DepMap CRISPR Gene Dependency 1.0 5.28063 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 105KC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07117 Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.5284 SKMEL19 DepMap CRISPR Gene Dependency 1.0 2.26003 OLIG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6756 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2318 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8788 LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7092 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.928348 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2188 olfactory receptor activity GO Molecular Function Annotations 2015 1.0 null PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2211 inner CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.924634 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.17377 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.272 GPCR downstream signaling Reactome Pathways 2014 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9285 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.7071 A101D COSMIC Cell Line Gene Mutation Profiles 1.0 null CHK2_KD_GSE54268_668_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null MAVER1 DepMap CRISPR Gene Dependency 1.0 3.34301 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.36789 NCIH322 CCLE Cell Line Gene CNV Profiles -1.0 -2.23828 cell part GO Cellular Component Annotations 2015 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.998348 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.40269 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.48791 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.48986 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.5641 SKBR3 DepMap CRISPR Gene Dependency 1.0 4.32856 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945405 NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1061 HSC-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7749 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.44704 sensory perception of chemical stimulus GO Biological Process Annotations 2023 1.0 null rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.895281 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 135.736 HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0727 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7752 M/G1 phase-specific MADS box-forkhead transcription factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.27 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW900 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.888388 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9285 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6772 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.971145 Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.128 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8066 inner SZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.836775 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 91.4329 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.30031 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4067 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928191 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.921775 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5983 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00989 EBC1 CCLE Cell Line Gene CNV Profiles 1.0 1.49437 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857766 Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0221 IM-95 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03379 SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.00236 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11542 TE11 CCLE Cell Line Gene CNV Profiles 1.0 1.40163 COLO824 DepMap CRISPR Gene Dependency 1.0 6.43209 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87923 Signaling by GPCR Reactome Pathways 2014 1.0 null HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.429 NCIH2170 DepMap CRISPR Gene Dependency 1.0 3.02845 Chromosome 2p16.1-p15 deletion syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.224 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2109 KMRC1 DepMap CRISPR Gene Dependency 1.0 2.05499 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.885064 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2822 WM1799 DepMap CRISPR Gene Dependency 1.0 5.39793 NCI-H1838 COSMIC Cell Line Gene CNV Profiles -1.0 -3.38669 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6901 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851806 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15963 ZNF324B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38162 Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.72492 Crx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.6333 NCIH716 CCLE Cell Line Gene CNV Profiles -1.0 -2.59442 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.25018 BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4619 signal transducer activity GO Molecular Function Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14303 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02745 cellular_component GO Cellular Component Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6027 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.88577 Dyslexia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.271 foxa1_23539448_lncap_lof_human_gpl10558_gse37314 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.190538 PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.084 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.05757 SW 1417 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26104 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 Signal Transduction Reactome Pathways 2014 1.0 null EPLC272H DepMap CRISPR Gene Dependency 1.0 2.64447 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01954 SubthalamicNucleus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.870432 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87014 NCI-H526 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.717935 orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2586 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851806 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22778 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9702 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.29989 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2763 CORL23 DepMap CRISPR Gene Dependency 1.0 5.77936 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23116 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.912898 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15024 dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3867 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.851788 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07853 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89617 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.929467 PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887528 UM-UC-1 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58565 sensory perception of smell GO Biological Process Annotations 2015 1.0 null plasma membrane GO Cellular Component Annotations 2015 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05074 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 78.8058 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0393 NCIH1395 CCLE Cell Line Gene CNV Profiles 1.0 1.3726 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.826316 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35749 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.872817 NCIH2073 CCLE Cell Line Gene CNV Profiles -1.0 -2.2811 SCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.45022 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7282 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.1835 HUPT4 CCLE Cell Line Gene CNV Profiles 1.0 1.40537 HCC38 DepMap CRISPR Gene Dependency 1.0 2.92724 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5518 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18951 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00666 posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.835729 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40585 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.823556 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.2262 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8379 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908476 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3292 SF295 CCLE Cell Line Gene CNV Profiles -1.0 -1.51215 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 Sensory Perception Reactome Pathways 2024 1.0 null ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26128 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7919 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 62.0197 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null NCI-H1944 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27754 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 97.6642 MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5199 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1319 VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.837431 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4851 PDPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70734 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4277 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45458 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.73987 QGP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.8064 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7679 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AD-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857766 SNU-387 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26141 outer CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24992 H2795 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHOS2 DepMap CRISPR Gene Dependency 1.0 2.92769 ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.215 signaling receptor activity GO Molecular Function Annotations 2015 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASH-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15571 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6645 EFO-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.856627 WM3772F DepMap CRISPR Gene Dependency 1.0 3.67058 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64556 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55826 biological_process GO Biological Process Annotations 2015 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.907878 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15024 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.98773 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.25354 speech-language disorder-1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.724 CHLA57 DepMap CRISPR Gene Dependency 1.0 3.35452 KDM5A ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3535 SNU869 CCLE Cell Line Gene CNV Profiles 1.0 1.85052 plasma membrane part GO Cellular Component Annotations 2015 1.0 null WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857766 CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.48599 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10859 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8594 PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53 Rummagene Transcription Factor Associations 2026 1.0 null POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0708 KPL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.48485 inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.848507 SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.81926 MIA PACA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852387 UWB1289 DepMap CRISPR Gene Dependency 1.0 3.28537 PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4135 TCF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3753 LB373-MEL-D COSMIC Cell Line Gene Mutation Profiles 1.0 null NTERA2CLD1 DepMap CRISPR Gene Dependency 1.0 4.19821 dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15941 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.1581 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30451 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8377 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7141 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.831849 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9371 primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.85648 HEC1 DepMap CRISPR Gene Dependency 1.0 2.27884 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00549 regulation of biological process GO Biological Process Annotations 2015 1.0 null HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1862 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3204 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9807 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.888237 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDST8 DepMap CRISPR Gene Dependency 1.0 3.34368 dorsolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04183 pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.933022 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.84 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1355 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.484 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null bladder GTEx Tissue Gene Expression Profiles 1.0 0.926771 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.1827 TT CCLE Cell Line Gene CNV Profiles 1.0 2.41948 COLO678 CCLE Cell Line Gene CNV Profiles -1.0 -1.92176 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47225 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.9249 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.24888 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.01794 JJ012 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893969 primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44883 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10859 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.938318 SW954 DepMap CRISPR Gene Dependency 1.0 2.61122 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13244 SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.28834 posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17839 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9665 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.3245 PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null COLO201 CCLE Cell Line Gene CNV Profiles 1.0 1.71735 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31916 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MOLP-2 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23055 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0726 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5295 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.15921 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null IGR39 CCLE Cell Line Gene CNV Profiles 1.0 1.37299 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 84.6448 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5171 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.86696 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null neurological system process GO Biological Process Annotations 2015 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.848507 MM127 DepMap CRISPR Gene Dependency 1.0 2.57585 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852387 BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4401 ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5144 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1077 Reading disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.266 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.599761 Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.7389 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.823 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4443 UACC-893 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15152 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.67004 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37423 molecular transducer activity GO Molecular Function Annotations 2015 1.0 null BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.76706 GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8953 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.82878 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.87489 A431 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1703 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5473 MALME3M CCLE Cell Line Gene CNV Profiles -1.0 -1.59347 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4306 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.27146 A498 CCLE Cell Line Gene CNV Profiles -1.0 -1.44933 CAS1 DepMap CRISPR Gene Dependency 1.0 2.24447 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7726 g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51559 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928191 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.874055 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.996549 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.8336 SARS-CoV MA15_Day2-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.30918 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64461 LMSU CCLE Cell Line Gene CNV Profiles 1.0 2.09601 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85497 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04429 TE5 CCLE Cell Line Gene CNV Profiles 1.0 1.78931 NCIH1792 CCLE Cell Line Gene CNV Profiles 1.0 1.93631 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85679 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8144 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05619 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57006 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35276 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.929743 ZR751 CCLE Cell Line Gene CNV Profiles -1.0 -1.53534 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.850761 SF539 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916822 RERFLCAD2 CCLE Cell Line Gene CNV Profiles 1.0 1.73121 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.823137 NCI-H1792 COSMIC Cell Line Gene CNV Profiles 1.0 2.10038 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE10 CCLE Cell Line Gene CNV Profiles 1.0 1.6256 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38024 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.5022 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9271 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27962 LS1034 DepMap CRISPR Gene Dependency 1.0 6.4731 GSE102870_11_v_0_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6877 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OLIG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8233 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4596 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62076 caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.877448 BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2211 NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31913 NCIH2405 CCLE Cell Line Gene CNV Profiles -1.0 -1.50007 JSC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null YMB-1-E COSMIC Cell Line Gene Mutation Profiles 1.0 null GEO COSMIC Cell Line Gene Mutation Profiles 1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03957 GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3159 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1988 IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34189 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844562 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T2-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null olfactory receptor activity GO Molecular Function Annotations 2023 1.0 null G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.982523 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4558 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.7187 Cellular anatomical entity COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4399 PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53 Rummagene Transcription Factor Associations 2026 1.0 null H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE186647,GSE217288_11_v_7_hnrnpc_human RummaGEO Gene Perturbation Signatures -1.0 null NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7117 membrane LOCATE Predicted Protein Localization Annotations 1.0 null SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5045 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5188 LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5009 NCI-H720 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7927 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9357 H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2171 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.81739 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9323 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2586 sensory perception of chemical stimulus GO Biological Process Annotations 2015 1.0 null A2058 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5047 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.1391 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4683 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.80514 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75704 MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.4528 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.982523 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30778 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.56 ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835248 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.8355 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08439 Prdm14 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.5671 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73492 Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857766 SNU1 DepMap CRISPR Gene Dependency 1.0 2.80185 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.861372 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90846 Lhx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.093 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65086 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.64708 LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7469 response to stimulus GO Biological Process Annotations 2015 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10859 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15394 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9048 cervix uteri GTEx Tissue Gene Expression Profiles 1.0 0.999892 UterusCorpus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.981163 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.0806 sensory perception of smell GO Biological Process Annotations 2023 1.0 null LAN2 DepMap CRISPR Gene Dependency 1.0 3.29122 primary auditory cortex (core)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.935949 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.856627 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18701 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null UMUC9 DepMap CRISPR Gene Dependency 1.0 3.01016 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857766 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22363 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3317 TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7955 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51601 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.973236 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6452 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4017 OLIG3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0572 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.237 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4128 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908476 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9549 Periglomerular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.049 PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Unnamed_6_MYCN Rummagene Transcription Factor Associations 2026 1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.35959 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5554 JVE127 DepMap CRISPR Gene Dependency 1.0 2.94928 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2994 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87014 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.0371 LNZ308 CCLE Cell Line Gene CNV Profiles -1.0 -1.63063 NCIH1838 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945405 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 73.1531 MELHO CCLE Cell Line Gene CNV Profiles -1.0 -1.35395 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.59 sensory perception GO Biological Process Annotations 2015 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34294 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.69159 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.39929 detection of stimulus GO Biological Process Annotations 2015 1.0 null Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.3796 FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4692 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.028 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6644 posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52033 Olfactory glomerulus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.48 g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null JOPACA1 DepMap CRISPR Gene Dependency 1.0 4.25092 IZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61213 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.991 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06012 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.833619 Speech disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.158 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.997645 LXF289 DepMap CRISPR Gene Dependency 1.0 2.01834 NKM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.973794 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.253 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0966 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41333 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.21528 A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.9038 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.863322 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5758 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05148 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0628 CEBPB_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null smoking cessation GAD Gene-Disease Associations 1.0 null PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4987 RRP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32243 NCIH727 CCLE Cell Line Gene CNV Profiles 1.0 1.37593 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63696 RVH421 DepMap CRISPR Gene Dependency 1.0 2.25082 HDQ-P1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40596 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.3869 KYSE-450 COSMIC Cell Line Gene Mutation Profiles 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.39358 Apraxia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.52364 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23055 Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.1032 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03623 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.858701 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.632 Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2522 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 75.45 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.61248 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.99442 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.991563 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 190.227 posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45742 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.872636 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.41386 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.80932 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37181 signal transduction GO Biological Process Annotations 2015 1.0 null Cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49318 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9905 D-542MG COSMIC Cell Line Gene Mutation Profiles 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26141 H3255 COSMIC Cell Line Gene CNV Profiles 1.0 2.10038 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55083 NEUROG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0635 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41163 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90696 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.3571 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87014 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.9289 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01094 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15394 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0501 Expression and translocation of olfactory receptors Reactome Pathways 2024 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.9256 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.886198 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1739 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.11759 COR-L311 COSMIC Cell Line Gene Mutation Profiles 1.0 null GI1 DepMap CRISPR Gene Dependency 1.0 2.64462 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.954888 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4184 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24386 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32298 CH157MN DepMap CRISPR Gene Dependency 1.0 2.02964 biological regulation GO Biological Process Annotations 2015 1.0 null ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1146 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908476 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.15552 receptor activity GO Molecular Function Annotations 2015 1.0 null FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6952 L-363 COSMIC Cell Line Gene Mutation Profiles 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4225 COV504 DepMap CRISPR Gene Dependency 1.0 2.08593 NCIH2052 DepMap CRISPR Gene Dependency 1.0 2.99599 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6353 binding GO Molecular Function Annotations 2015 1.0 null UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9384 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.245 POU3F2 ChEA Transcription Factor Targets 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16207 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.905444 mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.016859 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21258 Membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.2679 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36978 BARX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3246 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35422 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8932 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.6935 PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_3_FOXR2 Rummagene Transcription Factor Associations 2026 1.0 null SKMEL2 CCLE Cell Line Gene CNV Profiles -1.0 -1.96815 CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07027