association	dataset	threshold value	standardized value
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.312
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29381
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11359
OAW-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44535
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00779
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
synucleinopathy	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6606
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5511
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.799794
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59387
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57327
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325701
recognition	GeneRIF Biological Term Annotations	1.0	null
Autosomal recessive nonsyndromic deafness 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
KIAA1671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88115
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06129
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSHZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96412
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340757
Perrault syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Combined oxidative phosphorylation deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7071
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09931
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.601283
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946065
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.46076
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04169
CHSA8926	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40648
Perturb_4703_KD_Cpsf6_SRP265820	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.5968
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.278825
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.3225
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
Wolfram syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054389
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
SC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10183
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
impaired swimming	MPO Gene-Phenotype Associations	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64051
Otogelin	InterPro Predicted Protein Domain Annotations	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.872119
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.12014
Autosomal recessive nonsyndromic deafness 74	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14024
Autosomal recessive nonsyndromic deafness 32	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66717
Siphon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
PMC12612227-41523_2025_836_MOESM1_ESM.pdf-1-POU4F1_POU4F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45125
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13692
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48099
NB12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1371
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051422
configuration	GeneRIF Biological Term Annotations	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9159
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7642
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28349
Autosomal recessive nonsyndromic deafness 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.826
hemoglobinopathy	GWASdb SNP-Disease Associations	1.0	0.714954
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.33431
identification	GeneRIF Biological Term Annotations	1.0	null
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.331
Autosomal recessive nonsyndromic hearing loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19175
TP53	ChEA Transcription Factor Targets	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58831
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937696
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
ULK1_knockout_198_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.52223
abnormal semicircular canal ampulla morphology	MPO Gene-Phenotype Associations	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053676
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88483
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267791
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3498
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30747
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
Plague	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.79
SNU478	DepMap CRISPR Gene Dependency	1.0	2.10489
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99523
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15071
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21758
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1765
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.17563
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
DU-4475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910528
ONS-76	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	2.01609
CESS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01437
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23538
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06214
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.686
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9254
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12079
NCI-H2170	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LB2241-RCC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.103
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050915
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56062
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98187
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08539
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26931
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051892
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0706
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
hypoparathyroidism-deafness-renal disease syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14082
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.872556
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38695
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98187
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26925
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09189
Branchiootorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
synucleinopathy	GWASdb SNP-Disease Associations	1.0	1.12777
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39771
AMO1	DepMap CRISPR Gene Dependency	1.0	2.69043
Autosomal recessive nonsyndromic deafness 84A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00579
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.5745
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91895
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11895
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21975
Perturb_13570_KD_Islr_SRP160431	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37734
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
impaired righting response	MPO Gene-Phenotype Associations	1.0	null
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
stroke	GAD Gene-Disease Associations	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.271174
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05457
PMC6996670-6370386.f1.xlsx-Supplemental_table_2-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Bubonic plague	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.58128
Vestibular neuronitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.25
abnormal placing response	MPO Gene-Phenotype Associations	1.0	null
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02116
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16601
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.850296
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05232
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044145
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55824
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sensory perception	GO Biological Process Annotations 2015	1.0	null
KNS42	DepMap CRISPR Gene Dependency	1.0	4.7434
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754666
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19752
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58594
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
abnormal tectorial membrane morphology	MPO Gene-Phenotype Associations	1.0	null
Midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.901
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6719
KYO1	DepMap CRISPR Gene Dependency	1.0	2.2345
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.99536
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01296
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56072
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51614
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05803
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42076
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37608
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02286
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15146
Autosomal dominant nonsyndromic deafness 78	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.123
Autosomal recessive nonsyndromic deafness 67	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0448
BV-173	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04548
Postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Combined oxidative phosphorylation deficiency 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9662
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02205
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05066
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06535
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.26247
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88566
abnormal pinna reflex	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal recessive nonsyndromic deafness 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
Perturb_10655_OE_Ar_SRP123610	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
hemoglobins	GAD Gene-Disease Associations	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47443
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28741
GSE207914_5_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal ear physiology	MPO Gene-Phenotype Associations	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.533
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21429
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25091
all	HPO Gene-Disease Associations	1.0	null
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0256
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13404
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16118
SETD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62799
single-organism carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81397
abnormal posture	MPO Gene-Phenotype Associations	1.0	null
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26436
GSE160077,GSE160084_3_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2648
NCI-H720	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20796
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36722
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.042705
Jervell-Lange Nielsen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
MIA-PACA-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68475
ES8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.572
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.096
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25707
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41289
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Developmental dysplasia of the hip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
18787207-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97315
abnormal stationary movement	MPO Gene-Phenotype Associations	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4649
Sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
KNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.822
single-organism process	GO Biological Process Annotations 2015	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
17660535-TableS7	GeneSigDB Published Gene Signatures	1.0	null
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28114
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52077
arabinose metabolic process	GO Biological Process Annotations 2015	1.0	null
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54274
Autosomal dominant nonsyndromic deafness 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.968
SNU-283	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MET_knockout_249_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76376
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35994
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25189
mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27736
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
Deafness	DisGeNET Gene-Phenotype Associations	1.0	null
Autosomal recessive nonsyndromic deafness 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Usher syndrome type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24631
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68214
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18552
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Perturb_10667_OE_PAX3FOXO1_SRP371512	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.83365
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3252
abnormal postural reflex	MPO Gene-Phenotype Associations	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28349
Autosomal recessive nonsyndromic deafness 93	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
PMC11625982-AJH-100-10-s001.pdf-71-ZNF709_ZNF709	Rummagene Transcription Factor Associations 2026	1.0	null
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.566
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36722
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80791
Labyrinthitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2333
Autosomal recessive nonsyndromic deafness 102	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19146
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22457
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51404
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
Cochlear labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.934
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW872	COSMIC Cell Line Gene Mutation Profiles	1.0	null
head tilt	MGI Mouse Phenotype Associations 2023	1.0	null
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.295
Hemoglobins	dbGAP Gene-Trait Associations	1.0	0.089816
Sensory Perception	Reactome Pathways 2024	1.0	null
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.0353
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051764
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0488
anemia	GWASdb SNP-Disease Associations	1.0	0.377306
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
reduced fertility	MPO Gene-Phenotype Associations	1.0	null
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00669
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28318
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1242
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.38244
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02125
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41684
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5433
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Blastema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
SK-PN-DW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.3778
Scape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
decreased startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69741
hearing	GeneRIF Biological Term Annotations	1.0	null
SW1463	DepMap CRISPR Gene Dependency	1.0	2.30392
Autosomal recessive nonsyndromic deafness 111	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51445
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35483
microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.227752
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OSC20	DepMap CRISPR Gene Dependency	1.0	3.69744
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8919
basal ganglia disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	4.74212
Septicemic plague	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
Autosomal recessive nonsyndromic deafness 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204593
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.645512
NCIH1993	DepMap CRISPR Gene Dependency	1.0	6.13987
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57416
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16389
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01003
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16747
Autosomal dominant nonsyndromic deafness 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043742
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00669
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03039
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1095
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126649
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71821
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15327
NU-DUL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
von Willebrand factor, type D domain	InterPro Predicted Protein Domain Annotations	1.0	null
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27412
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16131
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01708
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02249
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.138
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.591
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
Perturb_15871_KO_PAX3/FOXO1_SRP293781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.5111
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49004
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863143
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0113
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9979
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08734
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
8505C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.546
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.31431
U-CH2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23902
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64366
TTC709	DepMap CRISPR Gene Dependency	1.0	2.50798
POP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3759
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.804
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19722
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26436
Clouston syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
JIMT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1869	DepMap CRISPR Gene Dependency	1.0	5.31262
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9841
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05355
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33706
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15727
Lateral wall of outer hair cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
l-arabinose metabolic process	GO Biological Process Annotations 2015	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29726
Athabaskan brainstem dysgenesis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21258
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02496
MM1S	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Baraitser-Winter syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2658
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75063
kidney	GTEx Tissue Gene Expression Profiles	1.0	0.899166
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04046
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048165
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42997
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.06377
JHH2	DepMap CRISPR Gene Dependency	1.0	4.03299
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5334
Cystine knot, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.862627
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5675
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53284
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
detached otolithic membrane	MPO Gene-Phenotype Associations	1.0	null
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
SCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BLUE1	DepMap CRISPR Gene Dependency	1.0	2.37111
Autosomal recessive nonsyndromic deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.847
neurological system process	GO Biological Process Annotations 2015	1.0	null
increased circulating aspartate transaminase level	IMPC Knockout Mouse Phenotypes	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.338
Perturb_7668_KD_IMP3_DRP003316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04861
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14877
D-263MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Scent gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
PMC9196635-Table1.docx-0-ALX3_ALX3	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heart	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC7914369-thnov11p3676s2.xls-BPTF-signature-geneId_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.3706
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3118
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5175
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.0081
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5436
abnormal semicircular canal morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.598
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868361
F12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05456
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.239
NCIN87	DepMap CRISPR Gene Dependency	1.0	3.4231
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	3.33471
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.604
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.26247
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1128
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32673
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.103
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02274
TYKNU	DepMap CRISPR Gene Dependency	1.0	3.73166
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16084_KO_Nfya_SRP270915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.51021
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14317
stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.631171
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.224
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53716
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.20633
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.141
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05347
Stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.610943
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72771
Microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.418
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
von Willebrand factor, type C	InterPro Predicted Protein Domain Annotations	1.0	null
Branchiootorenal syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0263
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69539
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.250702
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
proteinaceous extracellular matrix	GO Cellular Component Annotations 2015	1.0	null
Autosomal recessive nonsyndromic deafness 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
Nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066957
abnormal utricle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Autosomal recessive disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27255
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.102937
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7528
saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18068
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2886
abnormal otolith organ morphology	MPO Gene-Phenotype Associations	1.0	null
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 115	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.412
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70437
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.8301
Autosomal recessive nonsyndromic deafness 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.815
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive nonsyndromic deafness 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36333
Usher syndrome type 1J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980514
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.86228
larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.601686
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98187
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3307
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23456
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.481
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23011
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
Cell hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.00735
abnormal inner ear canal morphology	MPO Gene-Phenotype Associations	1.0	null
NCI-H1581	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.214895
speech	GeneRIF Biological Term Annotations	1.0	null
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51151
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40779
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868361
BICR10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05913
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21484
HCC1954	DepMap CRISPR Gene Dependency	1.0	3.78757
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12987
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12387
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20245
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71889
Stroke	dbGAP Gene-Trait Associations	1.0	0.441437
Fibrochondrogenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
chr11_17544490_A_C_b38	GTEx eQTL 2025	1.0	2.5594
moderate	GeneRIF Biological Term Annotations	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041604
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23321
Eye-muller cell	Tabula Sapiens Gene-Cell Associations	1.0	3.51083
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57379
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21873
Neurula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
Bart-Pumphrey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053976
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93326
PNMA6F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58505
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30605
Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59913
JVM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.72189
decreased startle reflex	IMPC Knockout Mouse Phenotypes	1.0	null
impaired swimming	MGI Mouse Phenotype Associations 2023	1.0	null
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.239
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044052
NB17	DepMap CRISPR Gene Dependency	1.0	4.18284
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.6261
UBTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03102
A673	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 76	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7587
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Von Willebrand's disease 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Usher syndrome type 1G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Trypsin Inhibitor-like, cysteine rich domain	InterPro Predicted Protein Domain Annotations	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28587
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32137
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
p1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15524
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFH-INO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14973
actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.298
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.847771
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92679
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21436
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.137
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Restrictive dermopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF717	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52355
PRDM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38462
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
remain	GeneRIF Biological Term Annotations	1.0	null
Marshall syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26187
Autosomal recessive nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.297
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0328
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09485
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.936199
Hereditary spherocytosis type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parkinson's disease	GWASdb SNP-Disease Associations	1.0	1.12777
MM160113	DepMap CRISPR Gene Dependency	1.0	4.10309
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
adult behavior	GO Biological Process Annotations 2015	1.0	null
Vestibulocochlear nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884208
KARPAS-422	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44952
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18073
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41684
EBF	MotifMap Predicted Transcription Factor Targets	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.395
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19722
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
CCLFPEDS0008T	DepMap CRISPR Gene Dependency	1.0	3.30073
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
parkinson disease	GAD Gene-Disease Associations	1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_5255_KO_Morc3_SRP318570	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.29794
Perturb_15034_KD_WDR5_SRP024294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23281
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051422
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
stereotypic behavior	MPO Gene-Phenotype Associations	1.0	null
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48872
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1657
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46872
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.076007
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.569
HC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88286
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.61807
mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315861
abnormal pinna reflex	MGI Mouse Phenotype Associations 2023	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
Rare genetic deafness	ClinVar Gene-Phenotype Associations 2025	1.0	null
Usher syndrome type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
Postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48046
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35752
Hyporeflexia	DisGeNET Gene-Phenotype Associations	1.0	null
BL1551 (HIPK2)	NURSA Protein Complexes	1.0	null
parkinson's disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29449
abnormal crista ampullaris morphology	MGI Mouse Phenotype Associations 2023	1.0	null
impaired balance	MPO Gene-Phenotype Associations	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0557
Sensorineural Hearing Loss, Bilateral	DisGeNET Gene-Disease Associations	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6106
immune system disease	GWASdb SNP-Disease Associations	1.0	0.05429
Alstrom syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
cellular_component	GO Cellular Component Annotations 2015	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94411
RB_Deficiency_GDS2757_644_mouse_Embryonic livers (day 12.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.067485
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38263
CCK81	DepMap CRISPR Gene Dependency	1.0	5.1227
Weissenbacher-Zweymuller syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.161
Hearing impairment	ClinVar Gene-Phenotype Associations 2025	1.0	null
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32297
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25482
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28741
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.77
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07103
abnormal otolithic membrane morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
membrane	GO Cellular Component Annotations 2015	1.0	null
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	0.986268
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant nonsyndromic deafness 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56288
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47543
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12471
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29914
GSE215086_0_v_1_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
18787207-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
head tilt	MPO Gene-Phenotype Associations	1.0	null
Benign paroxysmal positional vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.485
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03704
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
impaired hearing	MGI Mouse Phenotype Associations 2023	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06652
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
metabolic process	GO Biological Process Annotations 2015	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98187
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stereocilia ankle link complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.294
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041767
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44931
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11676
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.422
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.705
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.468819
Learning Disorders	CTD Gene-Disease Associations	1.0	1.10211
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83288
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.291
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867246
PMC11031761-mmc2.pdf-3-ZFPM2_ZFPM2	Rummagene Transcription Factor Associations 2026	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
abnormal ear physiology	MGI Mouse Phenotype Associations 2023	1.0	null
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.923
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00201
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81313
Enlarged vestibular aqueduct	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.761
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-6.15339
intracellular part	GO Cellular Component Annotations 2015	1.0	null
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18066
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21001
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69953
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5272
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26417
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15676
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epibranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82469
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05642
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10992
SKN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.713369
Cement gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8303
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30134
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04303
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.128
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.341176
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230931
transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.291417
COLO-824	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868361
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08678
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.9088
nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.58916
abnormal vestibular saccular macula morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15694
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.930308
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
tadpole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.639214
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0063
impaired balance	MGI Mouse Phenotype Associations 2023	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.24171
stroke	GWASdb SNP-Phenotype Associations	1.0	0.393559
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95441
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.06494
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38695
BL5432 (ERCC5)	NURSA Protein Complexes	1.0	null
Medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Autosomal recessive nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0472
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07359
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26415
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00579
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3991
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1063
HUO9	DepMap CRISPR Gene Dependency	1.0	2.15512
NZM3	DepMap CRISPR Gene Dependency	1.0	2.08486
Autosomal dominant nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
External encapsulating structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50584
abnormal crista ampullaris morphology	MPO Gene-Phenotype Associations	1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75573
sensorineural	GeneRIF Biological Term Annotations	1.0	null
Epidermal growth factor-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19238
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15199
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09972
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nonsyndromic hearing impairment	MGI Mouse Phenotype Associations 2023	1.0	null
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal motor coordination/ balance	MPO Gene-Phenotype Associations	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Stereocilium shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.213
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51351
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1989
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31425
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.975
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8003
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16367
Perturb_4543_KD_Chd4_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.44178
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16807
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15676
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
Tailbud stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18952
sensory perception of mechanical stimulus	GO Biological Process Annotations 2015	1.0	null
alpha-l-arabinofuranosidase activity	GO Molecular Function Annotations 2015	1.0	null
ischemic stroke	GWASdb SNP-Phenotype Associations	1.0	0.748581
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0555
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33663
SNU503	DepMap CRISPR Gene Dependency	1.0	2.02016
Amyotrophic Lateral Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Deafness	DisGeNET Gene-Disease Associations	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00779
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61689
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64279
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05084
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94214
Seizure	ClinVar Gene-Phenotype Associations 2025	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40648
DOV13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.861
Usher syndrome type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.129
Intellectual disability	ClinVar Gene-Phenotype Associations 2025	1.0	null
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0999
Perturb_15011_KO_Eed/Xist_SRP365240	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.02457
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07773
CORL279	DepMap CRISPR Gene Dependency	1.0	5.65148
U-118-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal inner ear vestibule morphology	MPO Gene-Phenotype Associations	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32579
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69452
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398735
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71188
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.714954
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.99442
autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2717
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pendred Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867246
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU-398	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65873
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16049
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50355
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
extracellular matrix	GO Cellular Component Annotations 2015	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	3.93062
Myosin IX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Post bronchodilator FEV1/FVC ratio	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41682
abnormal head movements	MPO Gene-Phenotype Associations	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.634
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC38	DepMap CRISPR Gene Dependency	1.0	5.94691
Usher syndrome type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02621
LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30276
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.39406
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11169
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29584
fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158129
villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213291
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03035
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-1.68248
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
GER cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.667
downsloping	GeneRIF Biological Term Annotations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of cerebral artery	GWASdb SNP-Phenotype Associations	1.0	0.3126
hyperactivity	MPO Gene-Phenotype Associations	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00779
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37391
GSE181513_0_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08813
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.466
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00909
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2714
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46479
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20168
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.76767
Whipple's Disease_macrophage_GSE16180	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.850898
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62373
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Autosomal dominant nonsyndromic deafness 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41588
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.641
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.25616
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86449
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
C80	DepMap CRISPR Gene Dependency	1.0	2.32984
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72598
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7698
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48137
abnormal cochlea morphology	MGI Mouse Phenotype Associations 2023	1.0	null
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	0.854796
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00629
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33178
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.214
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
deafness	MPO Gene-Phenotype Associations	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.757
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12044
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.317
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17558
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79492
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03788
LS-123	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detached otolithic membrane	MGI Mouse Phenotype Associations 2023	1.0	null
Autosomal dominant nonsyndromic deafness 65	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45786
sensory perception of sound	GO Biological Process Annotations 2015	1.0	null
absent pinna reflex	MGI Mouse Phenotype Associations 2023	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JHU-022	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38277
Retrocochlear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
Alpha-L-arabinofuranosidase B, arabinose-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06232
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2661
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58831
Otitis interna	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.951
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7062
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937696
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5061
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23113
PMC10042887-41419_2023_5742_MOESM4_ESM.xlsx-Table_S4-Table_S4_Overlap_genes_of_HOXB3_vs_HOXB3-_and_APC-KO_vs_APC-intact_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.141
absent startle reflex	MPO Gene-Phenotype Associations	1.0	null
chronic	GWASdb SNP-Phenotype Associations	1.0	0.481126
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.293151
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.767985
Vohwinkel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23113
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.873
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6398
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05221
KMS26	DepMap CRISPR Gene Dependency	1.0	4.42011
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.040181
PA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7496
clinical modifier	GWASdb SNP-Phenotype Associations	1.0	0.358325
Autosomal dominant nonsyndromic deafness 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.277
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
THOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49087
neurodegenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23735
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.982973
CHARGE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
behavior	GO Biological Process Annotations 2015	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02688
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hearing/vestibular/ear phenotype	MPO Gene-Phenotype Associations	1.0	null
cytosol	GO Cellular Component Annotations 2015	1.0	null
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46945
Pharyngeal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26153
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6882
foxa1_23539448_lncap_lof_human_gpl10558_gse37314	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.08309
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40563
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21832
abnormal inner ear morphology	MPO Gene-Phenotype Associations	1.0	null
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.612895
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15829
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.50008
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25802
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Amyotrophic lateral sclerosis 1	CTD Gene-Disease Associations	1.0	2.88009
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5296
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34578
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.944
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.847159
Autosomal recessive nonsyndromic deafness 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
artery disease	GWASdb SNP-Disease Associations	1.0	0.123598
Spemanns organizer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.674
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26668
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11646
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28587
abnormal hemoglobin	GWASdb SNP-Phenotype Associations	1.0	0.615542
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.088904
Autosomal dominant nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.195
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6942
TGFBR2_knockout_294_GSE36778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.37841
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.890726
Lateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
apical plasma membrane	GO Cellular Component Annotations 2015	1.0	null
altered righting response	MPO Gene-Phenotype Associations	1.0	null
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
blood vessel endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.219
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.81961
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2714
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35743
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55276
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.829765
PMC7726486-mmc3.xlsx-Sheet1-Table_S2_Differentially_expressed_genes_in_ZFP-VPR-362_samples_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.687
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895676
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85094
vascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89432
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41353
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4544
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900893
Autosomal recessive nonsyndromic deafness 18B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.359
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PrPC_KO_GDS4352_359_mouse_Developing hippocampus from adults (3-mo-old)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nonsyndromic Deafness	DisGeNET Gene-Disease Associations	1.0	null
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.8384
Jacobsen Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.142
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03763
disease	GWASdb SNP-Disease Associations	1.0	0.036122
Autosomal recessive nonsyndromic deafness 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9946
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.31886
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.250702
secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.537812
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10124
mRNA_WHSC2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15409
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0882
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
blood vessel	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61536
Serous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0284
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
LOUCY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.143635
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84735
interleukin-28 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07298
extracellular space	GO Cellular Component Annotations 2015	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00669
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.309
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	0.986268
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19674
GSE248858_6_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050806
deafness, autosomal recessive 18b	OMIM Gene-Disease Associations	1.0	null
hydrolase activity, hydrolyzing o-glycosyl compounds	GO Molecular Function Annotations 2015	1.0	null
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26379
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055545
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.362
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05113
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37417
abnormal semicircular canal morphology	MPO Gene-Phenotype Associations	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4544
t cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.80977
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15676
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.415337
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1972
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16131
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937696
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40144
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69714
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.998
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Juvenile myoclonic epilepsy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
plasma membrane region	GO Cellular Component Annotations 2015	1.0	null
Perilymphatic space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.586
abnormal membranous labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00779
auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.857153
D423MG	DepMap CRISPR Gene Dependency	1.0	2.19696
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4864
Autosomal dominant nonsyndromic deafness 67	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.40391
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.72279
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00689
adult locomotory behavior	GO Biological Process Annotations 2015	1.0	null
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42541
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67105
hyporeflexia	GeneRIF Biological Term Annotations	1.0	null
primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.307395
endothelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.107745
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90402
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939388
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33697
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0889
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04446
Deafness, autosomal recessive 18b	ClinVar Gene-Phenotype Associations	1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36593
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
abnormal vestibular saccule morphology	MPO Gene-Phenotype Associations	1.0	null
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
locomotory behavior	GO Biological Process Annotations 2015	1.0	null
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.849
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92607
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09939
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6719
chronic fatigue syndrome	GWASdb SNP-Disease Associations	1.0	0.564734
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1738
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15579
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37685
digeorge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.95745
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27314
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
abnormal vestibular labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72397
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05239
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parasubthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91879
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.98282
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60783
decreased vestibular hair cell stereocilia number	MGI Mouse Phenotype Associations 2023	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49978
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00832
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09931
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Superior semicircular canal dehiscence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
NB7	DepMap CRISPR Gene Dependency	1.0	3.39439
GSE168097_0_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Perturb_16406_KO_Vgll2_DRP005135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.29128
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19384
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
reduced fertility	MGI Mouse Phenotype Associations 2023	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	0.986268
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H2029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Myosin III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.298
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42142
good	GeneRIF Biological Term Annotations	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28292
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10485
abnormal placing response	MGI Mouse Phenotype Associations 2023	1.0	null
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.091809
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41428
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04871
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Usher syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
Autosomal recessive nonsyndromic deafness 66	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.921
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPMI-7951	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0196
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal ear morphology	MPO Gene-Phenotype Associations	1.0	null
Myf	MotifMap Predicted Transcription Factor Targets	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98187
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09915
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09088
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.152687
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16158
Parkinson Disease	dbGAP Gene-Trait Associations	1.0	0.426439
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8457
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39426
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53131
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867246
Usher syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38132
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76977
vascular endothelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.501369
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.355
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5347
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402901
Superior vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.765
DEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5059
LB647-SCLC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.244
Autosomal recessive nonsyndromic deafness 57	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36044
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.46079
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.07721
PMC11257629-media-3.xls-Dong_et_al_2023-Comparision_of_METTL3_KD_DEG_with_Dong_et_al_GRGs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal hearing electrophysiology	MPO Gene-Phenotype Associations	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.14541
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
Tectum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.754
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053649
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PCI-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57154
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02556
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.807
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PTGES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21784
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0662
BL2745 (C1D)	NURSA Protein Complexes	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64914
Asthma	DisGeNET Gene-Disease Associations	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58872
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85603
abnormal otolith morphology	MPO Gene-Phenotype Associations	1.0	null
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23497
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tympanum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.24165
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fibrochondrogenesis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
cause	GeneRIF Biological Term Annotations	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054551
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.53334
abnormal cochlea morphology	MPO Gene-Phenotype Associations	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	5.49272
SNU349	DepMap CRISPR Gene Dependency	1.0	5.62486
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980514
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.811
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
Uncharacterised domain, cysteine-rich	InterPro Predicted Protein Domain Annotations	1.0	null
vascular endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5597
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70137
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
NB10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19082
deafness	MGI Mouse Phenotype Associations 2023	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9461
POLR2A	ENCODE Transcription Factor Targets	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6996
Hodgkin's lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884208
hydrolase activity, acting on glycosyl bonds	GO Molecular Function Annotations 2015	1.0	null
GPATCH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37549
abnormal otolith morphology	MGI Mouse Phenotype Associations 2023	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3665
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62768
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17799
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78429
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040792
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21117
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32039
pituitary	GTEx Tissue Gene Expression Profiles	1.0	2.18987
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal utricle morphology	MPO Gene-Phenotype Associations	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046849
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	1.15101
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.765034
WAOSEL	DepMap CRISPR Gene Dependency	1.0	2.3976
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99336
Motion sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61052
Autosomal recessive nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.279
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67768
SNU886	DepMap CRISPR Gene Dependency	1.0	2.62272
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21539
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24602
Autosomal dominant nonsyndromic deafness 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.115
SYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9831
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323509
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
Hearing loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
cerebral ischemia	GWASdb SNP-Phenotype Associations	1.0	0.393559
inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11154
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
Retinal cone dystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
flat	GeneRIF Biological Term Annotations	1.0	null
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04497
abnormal auditory brainstem response	MPO Gene-Phenotype Associations	1.0	null
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33379
biological_process	GO Biological Process Annotations 2015	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94471
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.152
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.43146
monosaccharide metabolic process	GO Biological Process Annotations 2015	1.0	null
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28243
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17245
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6404
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01415
ES3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RTRAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86635
tick-borne encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
absent pinna reflex	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1547
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21036
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15148
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15187
impaired righting response	MGI Mouse Phenotype Associations 2023	1.0	null
PANC-10-05	COSMIC Cell Line Gene Mutation Profiles	1.0	null
loss	GeneRIF Biological Term Annotations	1.0	null
increased or absent threshold for auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
Toc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.553
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59609
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
TO14	DepMap CRISPR Gene Dependency	1.0	3.43714
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75611
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE130401_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36672
abnormal tectorial membrane morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937696
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.67
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04099
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19198
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68111
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26867
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25282
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1125
Epicuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.311
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL6340 (ANKRD17)	NURSA Protein Complexes	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6898
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48444
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0424
NCIH841	DepMap CRISPR Gene Dependency	1.0	2.28855
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
HBS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67484
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.30627
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16653
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11169
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FU97	DepMap CRISPR Gene Dependency	1.0	3.10338
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.062356
GSE84678,GSE93902_1_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00779
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
20963824-Table4	GeneSigDB Published Gene Signatures	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91945
increased or absent threshold for auditory brainstem response	MPO Gene-Phenotype Associations	1.0	null
proteinaceous extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
vestibular	GeneRIF Biological Term Annotations	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64279
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3106
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33706
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal vestibular saccule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
Autosomal recessive nonsyndromic deafness 99	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10784
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_4945_KO_Rybp/Yaf2/Prc1_SRP247114	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.51703
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43868
MTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34879
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20509
SF126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0206
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
circling	MGI Mouse Phenotype Associations 2023	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.333
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EW-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Myosin XV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.702
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31682
Perturb_13461_KO_Pnpla2P_SRP261793	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.12132
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07133
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15305
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
scores	GeneRIF Biological Term Annotations	1.0	null
NBSUSSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1585
Adult pleomorphic rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64844
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91482
Lateral vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
circling	MPO Gene-Phenotype Associations	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Meniere's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.882
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43149
HUH6	DepMap CRISPR Gene Dependency	1.0	3.44276
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pentose metabolic process	GO Biological Process Annotations 2015	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0321
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54013
Blastopore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
GNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38092
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10719
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835843
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.881
auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Sensory processing of sound	Reactome Pathways 2024	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Meniere disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19175
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232881
nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.42498
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2956
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04303
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54798
UACC-893	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10514
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LUDLU1	DepMap CRISPR Gene Dependency	1.0	3.73558
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37215
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3684
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68721
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15829
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66669
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.43
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16075
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tadpole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
BXPC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nonsyndromic	GeneRIF Biological Term Annotations	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8529165-Table_1.docx-0-ALX3_ALX3	Rummagene Transcription Factor Associations 2026	1.0	null
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.802
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897025
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21704
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17878
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77115
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937696
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.50103
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.14825
abnormal scala media morphology	MPO Gene-Phenotype Associations	1.0	null
Stereocilia ankle link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.294
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38778
Pneumonic plague	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832445
Endostyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.91253
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.75122
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81667
CD1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58869
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050782
Perturb_13462_KD_LncMyod_SRP192468	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.82785
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reports	GeneRIF Biological Term Annotations	1.0	null
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.838
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9832
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5785
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07558
GSE181749_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mild	GeneRIF Biological Term Annotations	1.0	null
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.682
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11674
GSE207914_0_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26124
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6603
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70253
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2167
present	GeneRIF Biological Term Annotations	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Autosomal recessive nonsyndromic deafness 109	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.245
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.945
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1806	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868632
Shukla-Vernon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
WDR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24509
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59609
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
abnormal startle reflex	MPO Gene-Phenotype Associations	1.0	null
abnormal locomotor coordination	MPO Gene-Phenotype Associations	1.0	null
Plant collar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14839
inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.94369
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58831
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
PMC12255709-43856_2025_1003_MOESM10_ESM.xlsx-Top_MR_results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
syndrome	GWASdb SNP-Disease Associations	1.0	0.342736
audiogram	GeneRIF Biological Term Annotations	1.0	null
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
impaired coordination	MPO Gene-Phenotype Associations	1.0	null
FHOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16808
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59703
m2 part of substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00125
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65086
NCI-N87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.842
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
Autosomal recessive nonsyndromic deafness 113	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
absent startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61419
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
CAKI1	DepMap CRISPR Gene Dependency	1.0	3.05885
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.952761
Auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.264
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06261
GSE110440_1_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090519
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15041
cell part	GO Cellular Component Annotations 2015	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046228
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
Tricellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
termporal pattern	GWASdb SNP-Phenotype Associations	1.0	0.481126
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02853
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489838
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00453
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.133552
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12471
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867246
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868361
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.049409
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.154
membrane region	GO Cellular Component Annotations 2015	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.09876
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.266042
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.065
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
DEL	DepMap CRISPR Gene Dependency	1.0	3.01922
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7201
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60168
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
increased circulating aspartate transaminase level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05221
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
GINS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
PGA1	DepMap CRISPR Gene Dependency	1.0	4.23791
congenital hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.714954
UBB_KO_GDS3906_491_mouse_Testis - 7 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06652
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51416
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GAK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Columnar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
Sensory processing of sound by outer hair cells of the cochlea	Reactome Pathways 2024	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260606
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16924
DIFI	DepMap CRISPR Gene Dependency	1.0	3.23553
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27723
Combined oxidative phosphorylation deficiency 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.997
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29457
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.29225
sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.999924
Autosomal recessive nonsyndromic deafness 35	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.811
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27917
impaired hearing	MPO Gene-Phenotype Associations	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68873
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28587
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05764
TE-441-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23321
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12249
OCI-AML2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70344
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99442
Acoustic neuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0795
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5946
Tail bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02581
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50685
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15146
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37773
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.08096
Epibranchial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
membrane part	GO Cellular Component Annotations 2015	1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02738
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3662
Autosomal recessive nonsyndromic deafness 49	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_14502_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.94541
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39876
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1688	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL-54	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.287
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06819
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946065
D-247MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Syndactyly type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0816
abnormal hearing physiology	MPO Gene-Phenotype Associations	1.0	null
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21986
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.249
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02125
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.054
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17878
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18512
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
K-562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.09366
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087436
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051865
OV-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39501
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6222
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58556
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72864
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.825
EW-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.82631
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal posture	MGI Mouse Phenotype Associations 2023	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5284
normocytic anemia	GWASdb SNP-Disease Associations	1.0	0.714954
PFKL_OE_GDS1079_201_mouse_myoblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5559
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALL-SIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.44622
impaired coordination	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_4212_KO_Mir140_SRP245562	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.68575
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.688817
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88747
NEC8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal cochlear labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062101
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48391
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.563
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81137
single-organism behavior	GO Biological Process Annotations 2015	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1638
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.99544
endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15857_KD_KDM3A_SRP248023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.91184
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.7119
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27778
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61465
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30336
abnormal otolithic membrane morphology	MPO Gene-Phenotype Associations	1.0	null