association	dataset	threshold value	standardized value
moderate	GeneRIF Biological Term Annotations	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.527
Autosomal recessive nonsyndromic deafness 32	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20034
GTEX-U8XE-1826-SM-4E3HV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16453
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61147
GSE61117_0_v_1_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946755
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
ZNF417	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60599
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876074
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881811
appendices_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.962124
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1949
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9146
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
1321N1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5969
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854759
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922486
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.559
Perturb_5925_KD_LOXL1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.98367
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41546
Myosin III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.477
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
chr12_80021509_A_G_b38	GTEx eQTL 2025	1.0	1.30413
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3446
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836202
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73648
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856044
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9987
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831456
Autosomal recessive nonsyndromic deafness 111	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.126
recognition	GeneRIF Biological Term Annotations	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.709
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62437
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
middle frontal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834302
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65344
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09452
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34442
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8609
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.072
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09339
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_11_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65122
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875287
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Churg-Strauss syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.588
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845659
Tectum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.198
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984486
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47233
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892318
endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3195
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	2.42655
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8555
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.19495
KDM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28575
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919584
Tatton-Brown-Rahman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8518
abnormal vocalization	MGI Mouse Phenotype Associations 2023	1.0	null
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	2.32672
GSE243199_1_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
lung disease	GWASdb SNP-Disease Associations	1.0	0.701367
Autosomal recessive nonsyndromic deafness 93	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.171
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5949_KD_PTBP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.10244
Perturb_5988_KD_ZNF207_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67398
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03448
NR1I2	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3689f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_6313_OE_GLDN_SRP407749	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
chr12_80023255_A_C_b38	GTEx eQTL 2025	1.0	1.99662
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07349
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23976
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4181_KO_Foxp1_SRP107214	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.91982
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
loss	GeneRIF Biological Term Annotations	1.0	null
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52374
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08631
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.809
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.079
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
LHX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14274
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5648
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60653
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.141
BZW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19264
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
Perilymphatic space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.970074
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.069787
Perturb_5986_KD_YY2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.4641
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993437
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21728
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26856
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4797
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10051
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937098
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.15665
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23395
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0076
hsa-miR-4645-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08383
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27898
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828389
GTEX-RU72-0826-SM-46MUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58451
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55006
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85593
all	GWASdb SNP-Phenotype Associations	1.0	0.038411
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.184395
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88786
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31221
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14805
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
all	HPO Gene-Disease Associations	1.0	null
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2527
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4921
vestibular hypofunction	HPO Gene-Disease Associations	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Spindle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
MC116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66363
Perturb_5904_KD_EBNA1BP2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.0101
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07655
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.183508
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832678
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2706
SAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64972
FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ST486	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.588
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5305
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16049
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04751
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957445
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38999
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66725
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07738
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
U178	CCLE Cell Line Gene Expression Profiles	1.0	1.86166
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
KMS11	CCLE Cell Line Gene CNV Profiles	1.0	1.61993
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.09628
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28452
abnormal skin morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
SKRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05135
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18728
heart_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.51745
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0511
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
HUH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8755441-mmc3.xlsx-ISGsets-IFNs-averageFC-ISGF3-ZP_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2813
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.951472
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6451
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879892
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21885
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86374
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
ZNF728	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44209
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51529
Otosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51041
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4123
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00273
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869802
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	0.8427
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971397
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13687
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.844
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.076726
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_5890_KD_BCLAF1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.217
YY2_KD_GDS3788_490_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35365
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12466
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901942
Perturb_5950_KD_QKI_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.68863
Perturb_5979_KD_WDR46_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.7549
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.37955
hsa-miR-4766-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Perturb_5970_KD_SUZ12_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.32856
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910617
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.114
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33078
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
andor	GeneRIF Biological Term Annotations	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0227
GTEX-RTLS-1226-SM-46MUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65187
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50974
Mel-18_KD_GDS2724_103_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Blood vessel	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968987
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08668
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882728
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964162
BCP1	CCLE Cell Line Gene Expression Profiles	1.0	1.56772
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.72145
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68666
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Frontonasal dysplasia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Perturb_8513_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.94238
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
GTEX-O5YT-0726-SM-3MJHA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981827
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84704
K-562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.298
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47918
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81298
Perturb_5982_KD_YBX1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.55956
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1126
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877477
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955466
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
Autosomal recessive nonsyndromic deafness 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29219
Stereocilium shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.391
Midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.688
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.50764
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
Rare genetic deafness	ClinVar Gene-Phenotype Associations 2025	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1163
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875638
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8885
bone resorption disease	GWASdb SNP-Disease Associations	1.0	0.720532
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23698
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960723
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20651
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_6_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79878
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX10	JASPAR Predicted Transcription Factor Targets	1.0	null
NCIH747	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18829
Posterior amorphous corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61418
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33078
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.884496
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0657
Perturb_5901_KD_CUX1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.1079
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8495
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
hsa-miR-302f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MITD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27825
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69691
hsa-miR-429	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42196
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47526
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00319
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
ETFDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18966
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.412
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65746
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KNS60	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96955
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
configuration	GeneRIF Biological Term Annotations	1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
testis	HPA Tissue Protein Expression Profiles	1.0	1.30253
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17784
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28002
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93021
Perturb_8633_KO_Sh3gl1/Sh3gl2_SRP082219	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.00416
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11733
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5956
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.76575
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875792
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11323
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SIU7-1326-SM-4BRWW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11803
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75987
hsa-miR-107	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_5939_KD_NONO_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.28302
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03745
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07823
Perturb_1418_OE_Suv39h1_SRP150158	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
ASPC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62783
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0893
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27712
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43152
NCIH2170	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55441
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832506
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61228
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5279
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2632
GSE126402_2_v_3_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Usher syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859496
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3059
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27645
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0732
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855613
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sensorineural	GeneRIF Biological Term Annotations	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2504
RCM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
U937	CCLE Cell Line Gene CNV Profiles	1.0	2.01711
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIJK	CCLE Cell Line Gene Expression Profiles	1.0	1.481
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826711
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09885
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966842
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62149
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935799
KM12	CCLE Cell Line Gene CNV Profiles	1.0	1.50189
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88154
Autosomal recessive nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3748
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-OIZI-1326-SM-3NB1B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946321
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840821
Endothelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21841
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.735
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980944
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69965
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
Hearing impairment	ClinVar Gene-Phenotype Associations 2025	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48427
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35309
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935738
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.918
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5902_KD_DDX17_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.3683
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834046
Heart	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5806
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897142
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61435
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84069
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978385
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.128566
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal dominant nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SDHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01477
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56777
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895237
Space motion sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0911
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33818
Bart-Pumphrey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
LTC4S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11108
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.70673
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0139
hsa-miR-3689e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20092
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05179
present	GeneRIF Biological Term Annotations	1.0	null
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56303
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.097137
MOGGUVW	CCLE Cell Line Gene Expression Profiles	1.0	2.13362
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 18B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.051
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
Autosomal dominant nonsyndromic deafness 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77771
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984639
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38644
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8324
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52982
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.0
SNU1105	CCLE Cell Line Gene Expression Profiles	1.0	1.46356
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11159
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87146
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.49
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95708
GTEX-S341-0426-SM-4AD5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875963
Perturb_5932_KD_MPHOSPH10_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.42938
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21194
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Stratum germinativum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40261
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27886
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38275
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5004
Autosomal recessive nonsyndromic deafness 115	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.449
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.824
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9022
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880713
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.147
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
ATR_KD_GSE54268_664_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09327
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09306
ATM_KD_GSE54268_661_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.94
Autosomal recessive nonsyndromic deafness 84A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71363
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.986
Perturb_5913_KD_HDLBP_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.13163
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22547
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.5927
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6521
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0572
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958048
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8125
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6005
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875139
1221 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.201
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.588
vestibular	GeneRIF Biological Term Annotations	1.0	null
Perturb_5940_KD_PES1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.2171
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84754
Autosomal recessive nonsyndromic deafness 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.427
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913387
GSE131887_1_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
endothelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5789
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87768
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-SOX14-sequence_name_SOX14	Rummagene Transcription Factor Associations 2026	1.0	null
remain	GeneRIF Biological Term Annotations	1.0	null
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08393
retinopathy	GWASdb SNP-Phenotype Associations	1.0	0.458315
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
CAKI2	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25539
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9545
heart	GTEx Tissue Gene Expression Profiles	1.0	1.33875
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04543
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858224
Epibranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
SCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5753
Deafness, autosomal recessive 84b	ClinVar Gene-Phenotype Associations	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02979
BHT-101	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94869
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12911
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8682
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13534
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950056
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945802
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.529
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30683
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0111
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926634
GSE138789_0_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.761
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858556
Perturb_5944_KD_PPAN_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.39998
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223334_1_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2444	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50814
retinal vascular disease	GWASdb SNP-Disease Associations	1.0	0.405843
hsa-miR-3121-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.085258
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04152
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2963
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Meniere's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.078
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25202
diabetic retinopathy	GWASdb SNP-Disease Associations	1.0	0.537384
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03127
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	1.92902
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96035
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11607
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88626
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.071987
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66151
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.733
Nonsyndromic Deafness	DisGeNET Gene-Disease Associations	1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.184395
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65105
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966041
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.74679
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.55075
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2938
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836202
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28056
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
decreased startle reflex	IMPC Knockout Mouse Phenotypes	1.0	null
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955466
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917123
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43496
GSE72491_0_v_1_pcbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69312
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1077
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
osteoporosis	GWASdb SNP-Disease Associations	1.0	0.79774
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Meniere disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869083
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79013
KMM1	CCLE Cell Line Gene Expression Profiles	1.0	1.59634
hsa-miR-3120-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.051
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5319
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PL18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
miR-124_OE_GDS2657_771_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE172490_5_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
blood vessel	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00177
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.1445
abnormal startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pendred Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79379
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2203
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41197
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96498
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.046
NCIH1703	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54363
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38043
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.79484
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.07694
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834957
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8505
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86339
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.738
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Von Willebrand's disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00299
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9629
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24881
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7148
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848556
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.117894
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80533
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-0.884496
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.317
sc11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74195
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus	GTEx Tissue Gene Expression Profiles	1.0	0.871779
Perturb_17356_KO_Mir22_SRP216410	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.96182
JAR	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
Perturb_5917_KD_HNRNPL_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.69617
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80549
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883917
abnormal startle reflex	IMPC Knockout Mouse Phenotypes	1.0	null
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80869
Small_Intestine-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.0258733
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01726
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836947
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47933
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09847
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226770_3_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.05
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.85117
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OXSM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
GTEX-OXRK-1426-SM-3NB19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910009
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54133
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948689
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00995
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49229
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9738
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1244
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
Perturb_5954_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.75677
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44314
Stereocilia ankle link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.472
Perturb_2088_OE_APTX_SRP174572	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70771
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.474
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	0.961656
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96498
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.502206
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25596
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00327
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	1.74542
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15427
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59529
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5397
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.30253
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.6931
TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Autosomal dominant nonsyndromic deafness 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.27
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01954
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32099
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
Autosomal recessive nonsyndromic deafness 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
parahippocampal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884744
Perturb_15718_OE|KD_Ctcf|Smarca5_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.93297
VMRCLCD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76704
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Neurilemoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41561
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932793
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3632
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1382
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834884
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04083
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
mode of inheritance	HPO Gene-Disease Associations	1.0	null
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
OVCA433	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4918
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
Autosomal dominant nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928726
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.67634
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95076
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867734
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19229
GTEX-RWSA-1326-SM-47JX9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8561
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61606
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95211
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34399
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.174
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97467
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5833
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901776
hsa-miR-4279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCI-H146	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leads	GeneRIF Biological Term Annotations	1.0	null
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_5899_KD_CHAF1A_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.69329
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30918
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82671
posterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77573
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91827
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-17-ZNF367_ZNF367	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6176
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35103
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45813
Perturb_5914_KD_HMGA1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.1503
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.75565
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
LYSP100-associated nuclear domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.693745
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10776
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KALS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-144	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0053
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.43617
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1003
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.205
APLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76981
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884373
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11358472-41467_2024_51851_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_4_gene_expression_levels_for_323_genes_connected_to_EWS-WT1_in_JN-DSRCT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18885
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969122
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926576
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-3.16762
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26749
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.892
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Columella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893412
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
acellular	GeneRIF Biological Term Annotations	1.0	null
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24942
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955466
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
hsa-miR-3942-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8803
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874774
Perturb_5943_KD_POLDIP3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.46115
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16129
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07768
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.148588
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55629
Sensory processing of sound	Reactome Pathways 2024	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.27231
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89385
COQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27846
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF853	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48137
vascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8682
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11184
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982415
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881663
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.005
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905714
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
hearing	GeneRIF Biological Term Annotations	1.0	null
NOS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.61408
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-OTX1_OTX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4834
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21487
HK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15768
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834957
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.1712
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9113
hsa-miR-145	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5878
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23464
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
3-methylcrotonyl-CoA carboxylase complex, mitochondrial	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46739
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.877035
Perturb_5931_KD_MBNL1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.98513
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.943163
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84961
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.606
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836947
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76181
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5674
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86295
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50415
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97521
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	2.20911
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37612
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.954
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08888
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01676
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51922
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7212
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29524
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_5927_KD_LTBP2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.35913
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995714
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5205
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01472
TE-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62586
hsa-miR-4793-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06622
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.234
ear	GeneRIF Biological Term Annotations	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07734
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00558
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966713
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
muscle tissue disease	GWASdb SNP-Disease Associations	1.0	0.233918
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894119
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9188
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.86559
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5846
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
decreased thigmotaxis	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38757
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19555
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875058
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6094
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832001
Perturb_5903_KD_DDX5_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2622
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	3.06199
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20361
Autosomal recessive nonsyndromic deafness 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9413
Autosomal recessive nonsyndromic deafness 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral group of nuclei, left, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.899866
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26641
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.682
Perturb_5983_KD_YBX3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.65455
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
STAT3	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3130-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36124
downsloping	GeneRIF Biological Term Annotations	1.0	null
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.948
Perturb_3745_KO_Usp8_SRP301242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC12183081-41388_2025_3375_MOESM8_ESM.xlsx-Sheet1-Table_S7_List_of_differentially_alternative_splicing_genes_in_osteosarcoma_cell_lines_after_knocking_down_the_YBX1_gene_P_0_05_Related_to_Fig_6C_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.588
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2132
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39597
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.167666
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5355
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0613
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75426
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22274
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.49596
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62247
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-SNU-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6639_KD_ZBP1_SRP298473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.5553
hsa-miR-579	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20478
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22312
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
GOS3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48999
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54236
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0736
USP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59588
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60441
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10308
Autosomal recessive nonsyndromic hearing loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-DMBX1_DMBX1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891807
Perturb_5971_KD_TAF15_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.50595
TMED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00055
hyporeflexia	GeneRIF Biological Term Annotations	1.0	null
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24351
NBSUSSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22418
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59842
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68541
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66892
HCC1806	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.046207
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01046
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849207
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.899
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80375
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09191
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RO82-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52636
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09097
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	2.30969
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
MONOMAC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81579
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875291
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.026
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66969
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44576
wm115	HPA Cell Line Gene Expression Profiles	1.0	1.4583
CYP20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23776
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29567
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.327264
GSE174735_4_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-0426-SM-4DXT4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0085
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
HOP-92	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.449
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64743
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24099
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826711
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03872
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923737
NCIH522	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41529
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994374
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937014
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73405
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03085
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3093
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.42208
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0428
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00177
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	1.0	3.06279
decreased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_8500_OE_RAS_SRP150620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.8955
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1487
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55962
PMC6538374-elife-45672-supp3.xlsx-DEGs-Genes_expressed_at_lower_levels_in_SMARCB1_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.398811
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19126
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8259
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81879
Auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846499
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13395_KD_KDM6B_SRP096375	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868961
Myosin XV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.881
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860202
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80863
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_15349_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.5331
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.441
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02342
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.327
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.031
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90935
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12693
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46642
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881413
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.588
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.27124
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.755
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939124
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
affect	GeneRIF Biological Term Annotations	1.0	null
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0095
placenta_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.853497
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Vestibulocochlear nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.668
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.348
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52359
hsa-miR-1322	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01719
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18142
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	1.34912
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66334
Hypertrophy of breast	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946684
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17153
Myosin phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.938
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5888
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841525
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02254
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3155
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Medroxyprogesterone acetate_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0236281
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863683
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9838
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTF3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28292
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966041
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.58
Poliomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4871
Acoustic neuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43978
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02612
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02181
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6626
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2859
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950281
Cement gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.565
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24198
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32593
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18838
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953682
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.511
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25164
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836202
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6141
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882681
kidney	HPA Tissue Gene Expression Profiles	1.0	2.24717
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855604
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 67	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
decreased startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33078
NR1H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20108
Pyridoxine (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0236547
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1482
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864509
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2826
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00014
GSE239844_8_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.17296
Deafness	DisGeNET Gene-Disease Associations	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
u87	HPA Cell Line Gene Expression Profiles	1.0	1.22006
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.515
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Epicuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
MC-CAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Motion sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38419
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04659
HCaRG_OE_GDS2426_711_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HBEGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15122
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41985
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89482
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829234
EFO-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51467
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_15_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC12A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24027
BT20	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36086
hsa-miR-942	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
eye disease	GWASdb SNP-Disease Associations	1.0	0.097137
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53751
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Usher syndrome type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
Autosomal dominant nonsyndromic deafness 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.262
Integrin alpha8-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3413
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947768
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PMC8283158-mmc2.xlsx-TCF4_Glut-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4808
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4409
Perturb_14246_KO_FOXM1_SRP328179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7379
CLDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50966
Autosomal dominant nonsyndromic deafness 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.861
Superior semicircular canal dehiscence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08551
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15378
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962573
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.945967
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4189
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.09
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59309
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Perturb_7708_KD_Spt6_SRP132004	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.98359
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.437
Urinary bladder epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98394
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5131
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43686
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9351
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47758
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8467
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RUSQ-0926-SM-47JWU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33002
ultimately	GeneRIF Biological Term Annotations	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8933
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4843
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973107
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2504
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65771
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04908
Perturb_5959_KD_RPF2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.23762
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24182
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.491
TLDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03795
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.128
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836202
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.002
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57118
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0618
Usher syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00943
Perisynaptic extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33588
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.64984
GTEX-R55D-1226-SM-48FE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892943
GTEX-NFK9-2026-SM-3LK5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844614
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5249
GTEX-XQ3S-1026-SM-4BOPJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83205
SCC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100446_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54505
Perturb_5978_KD_UTP3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.084
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836567
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951362
Serous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44748
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90419
Vascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-PSDG-1426-SM-48TD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07021
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 67	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9096
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5329
PMC7450273-mmc2.xlsx-ST12-Unnamed_4_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01634
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
good	GeneRIF Biological Term Annotations	1.0	null
abnormal skin morphology	IMPC Knockout Mouse Phenotypes	1.0	null
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MLMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76939
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3134
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12283
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43888
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81381
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-RWS6-0726-SM-47JXI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24401
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6078
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
COR-L95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85516
TT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5503627-oncotarget-08-39497-s003.xlsx-hypo_in_shUHRF1_KD-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.49319
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0287
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28062
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16147
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41279
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99657
ETS1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14144
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.8
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.948
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51474
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13982
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88331
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41331
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00977
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960252
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.167666
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
inferior frontal gyrus, orbital part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991336
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
abnormal coat/ hair morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12731
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.187037
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892655
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11042
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66063
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54356
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42145
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96895
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62897
PMC7057110-MGG3-8-e1128-s001.docx-0-ALX3_ALX3	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_7505_OE_ADARB1/ILF3_SRP195616	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.59534
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41998
S-117	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08668
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.29466
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04613
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49058
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828389
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50159
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.903073
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77418
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5938_KD_NCOA7_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.09377
hsa-miR-3664-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.419
cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49229
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7717
superior frontal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846588
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989704
audiogram	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841231
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-R53T-1026-SM-48FCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08863
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive nonsyndromic deafness 74	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843402
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Autosomal recessive nonsyndromic deafness 113	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.123
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70172
GSE120595_0_v_1_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04354
DDX31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30147
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23707
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.833
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15274
GTEX-S95S-0326-SM-4B66U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19036
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2884
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985979
Extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956256
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.4914
Perturb_14502_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.5145
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0736
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12008
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.4744
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
abnormal coat/ hair morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Fetal Heart	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.835247
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.060318
scores	GeneRIF Biological Term Annotations	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
speech	GeneRIF Biological Term Annotations	1.0	null
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.40398
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53867
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15604
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
Perturb_5953_KD_RBM26_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.69618
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5347_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.20703
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	2.47853
Autosomal dominant nonsyndromic deafness 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19573
GTEX-U3ZN-1826-SM-4DXUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972695
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99128
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29284
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0618
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5171
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7047
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3834
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37993
superior frontal gyrus, right, medial bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.998979
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80656
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Sensory processing of sound by outer hair cells of the cochlea	Reactome Pathways 2024	1.0	null
PMC13127299-mmc2.xlsx-PBX1_kdRNAseq-hgnc_symbol_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16811
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66045
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891807
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.054893
GTEX-VJYA-0626-SM-4KL1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56401
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05355
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10776
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24737
JHU-011	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880029
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.848
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10042
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02824
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30655
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841029
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81403
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45977
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70329
EW-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0174
Perturb_5929_KD_MBD3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.46929
Autosomal recessive nonsyndromic deafness 79	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ATXN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0207
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HLFA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58411
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5057
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908784
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942937
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
ZKSCAN1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83252
hsa-miR-4771	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0893
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88095
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872179
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.46789
Perturb_5985_KD_YTHDC1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.39486
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3148
ARH-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991404
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04206
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0552
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3689a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NCI-H378	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42716
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
chr12_80020318_C_A_b38	GTEx eQTL 2025	1.0	1.75507
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18008
VMRC-RCZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888657
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37612
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41086
HS746T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56342
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.631
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97448
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53388
Vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.588
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29288
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BV-173	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42144
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980155
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36165
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Blood vessel endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3058
obesity	GWASdb SNP-Disease Associations	1.0	0.513385
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1736
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10512
placenta	HPA Tissue Gene Expression Profiles	1.0	0.892226
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956256
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1094
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0517
JVM3	CCLE Cell Line Gene CNV Profiles	1.0	1.44427
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0893
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8991
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879096
GTEX-Q2AG-1226-SM-4GICA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3852
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.043849
methylcrotonoyl-CoA carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901483
Perturb_5961_KD_SAFB_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.01471
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15479
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40086
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.74706
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08173
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.83339
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65759
PSN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51674
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51529
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ2-0926-SM-4DXU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15815
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.69063
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3043
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5223
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26721
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.35228
PMC6996670-6370386.f1.xlsx-Supplemental_table_2-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152432_6_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5924_KD_LLPH_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.1942
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4945
hsa-miR-3692	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26117
Vestibular neuronitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.668
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5551
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12
Skin mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.573
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.286
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
TAF5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03037
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01594
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12325
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0444
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873934
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3675-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894323
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBK-0726-SM-3LK5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940263
Retrocochlear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
Perturb_15241_KD_ERCC6L2_SRP349996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.37935
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07692
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
U251MG	CCLE Cell Line Gene Expression Profiles	1.0	1.56065
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26886
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956256
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54921
EIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83622
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1132
Perturb_5947_KD_PRMT1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.57435
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94262
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881663
WM278	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6005
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01654
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07694
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20768
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21728
Autosomal recessive nonsyndromic deafness 102	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99396
BT474	CCLE Cell Line Gene CNV Profiles	1.0	2.05248
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12496
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22021
Usher syndrome type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89983
SK-CO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9011
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.4579
TRIM33_KD_GDS4071_449_human_HMEC-TR mammary epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
mild	GeneRIF Biological Term Annotations	1.0	null
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8558
Autosomal dominant nonsyndromic deafness 40	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19127
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935235
SUPM2	CCLE Cell Line Gene Expression Profiles	1.0	1.43198
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3978
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_1321_KD_VIRF3_SRP201368	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.00129
abnormal bone structure	GWASdb SNP-Phenotype Associations	1.0	0.13229
HCC1937	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03851
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04533
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
hsa-miR-3691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.652
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30305
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.854523
hsa-miR-4727-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Autosomal recessive nonsyndromic deafness 109	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905176
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-548g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
KMS18	CCLE Cell Line Gene Expression Profiles	1.0	1.99587
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64291
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6597
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4032
PPFIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72408
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18732
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87596
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62668
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38887
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00736
heart	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22447
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891807
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9181
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.935143
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942328
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.079526
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19425
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34283
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.55812
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86238
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.78661
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4687
WIL2-NS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0614
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0596
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07152
Perturb_4587_KO_Socs3_SRP074146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.37608
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.602605
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Benign paroxysmal positional vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
Autosomal recessive nonsyndromic deafness 63	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0272
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2821
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36442
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27717
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.45
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03306
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14586
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884873
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919025
FASLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20703
WDR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24509
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844239
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33279
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23486
Spiral organ cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08101
miR-124_OE_GDS2657_770_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZR7530	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09207
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
Perturb_5898_KD_CEBPZ_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.7796
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93782
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7217
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-1298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3053
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836947
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0726-SM-4DM5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917206
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
bone remodeling disease	GWASdb SNP-Disease Associations	1.0	0.485074
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S1_LMS_SNV-Supplementary_Data_1_Most_Recurrent_Non-Synonymous_Point_Mutations_in_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1309
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04735
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66266
Perturb_17229_KO_Tsc1_SRP096336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.99614
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08668
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9693
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26617
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.688
blood vessel endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11598
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_5895_KD_CCDC137_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.4419
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05593
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vascular endothelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99123
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891461
HDAC2	ENCODE Transcription Factor Targets	1.0	null
LS411N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79441
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873867
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PPP1R15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39962
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11981
flat	GeneRIF Biological Term Annotations	1.0	null
HEI-193 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.876457
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965513
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55243
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TECPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14346
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99754
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956234
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57739
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935633
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30462
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5556
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00105
hsa-miR-548ah	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0211
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.733
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perineuronal net	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3767
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23908
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00177
End stage renal disease x APOL1 genotype interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
Tympanum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71826
GTEX-U3ZH-1126-SM-4DXUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924084
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955801
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46331
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35461
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.458
vascular endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.909
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0988
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101546_2_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44004
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53359
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894775
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31585
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3915
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
abnormal vocalization	IMPC Knockout Mouse Phenotypes	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.167666
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2724
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32299
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956441
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ASIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73105
SMAD4	ChEA Transcription Factor Targets	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22519
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9738
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.932192
Autosomal recessive nonsyndromic deafness 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0444
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00177
Perturb_5960_KD_RPS19BP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.2138
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-361	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2692
nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43971
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43227
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842339
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.998729
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10852026-sxad088_suppl_supplementary_tables.pdf-3-NR1H4_NR1H4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20707
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.09628
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.8341
Human - Motor Cortex - Cluster - RORB+ OTOGL+ Layer 3 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3051
DDX53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23543
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893191
Perturb_5915_KD_HNRNPA2B1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.69855
Perturb_5957_KD_RIF1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.48469
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02278
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.77811
Stereocilia ankle link complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.472
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1543
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
inner	GeneRIF Biological Term Annotations	1.0	null
Nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
SNU489	CCLE Cell Line Gene Expression Profiles	1.0	1.38711
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6308
GAMG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-137	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34037
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9623
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.239
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54637
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.0595
Perturb_5892_KD_CBX1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6037
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852795
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17623
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64302
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957598
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873119
Perturb_5994_KD_ZNF622_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.22114
SYNCRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06527
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61427
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
GTEX-P78B-1126-SM-3P615	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20267
Autosomal recessive nonsyndromic deafness 66	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.076
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	1.52033
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79657
GSE180951_6_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07128
muscular disease	GWASdb SNP-Disease Associations	1.0	0.211824
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Arnt::Hif1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2212
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880515
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845156
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22174
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-genes-Up-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31311
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03753
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1894
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0606
hsa-miR-4448	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.8341
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955617
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of bone mineral density	GWASdb SNP-Phenotype Associations	1.0	0.620705
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
Von Willebrand's disease 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC2820517-pcbi.1000671.s006.txt--ZNF449_ZNF449	Rummagene Transcription Factor Associations 2026	1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
Cochlear labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89749
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11768
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973082
Perturb_5958_KD_RPF1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.3453
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
retinal disease	GWASdb SNP-Disease Associations	1.0	0.170556
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0892
GTEX-V955-1226-SM-4JBI9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01565
GTEX-QMRM-0926-SM-447BR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16187
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
H3118	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948865
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85313
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9277
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96193
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
HEI-OC1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.201516
disease	GWASdb SNP-Disease Associations	1.0	0.041064
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833955
superior frontal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85821
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7224
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9502
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38587
deafness, autosomal recessive 84b	OMIM Gene-Disease Associations	1.0	null
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11375
HMCB	CCLE Cell Line Gene Expression Profiles	1.0	1.89153
Charcot-Marie-Tooth disease X-linked recessive 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular endothelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.382
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02644
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4544
hsa-miR-103a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6404
Autosomal recessive nonsyndromic deafness 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13046
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01362
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr12_80025920_A_G_b38	GTEx eQTL 2025	1.0	1.63512
GSE82104,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955466
bone disease	GWASdb SNP-Disease Associations	1.0	0.229245
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10648
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
hsa-miR-3609	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.34756
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
KARPAS299	CCLE Cell Line Gene Expression Profiles	1.0	1.7154
middle frontal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13382
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40736
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1407
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5896_KD_CCDC59_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.38953
Perturb_5952_KD_RBM15_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.23877
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56033
GSE201520_8_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3689b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61975
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01023
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56079
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.974
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37556
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09802
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43152
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854358
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48885
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
myopathy	GWASdb SNP-Disease Associations	1.0	0.233918
vestibular dysfunction	HPO Gene-Disease Associations	1.0	null
Perturb_5897_KD_CCDC86_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.63213
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.43814
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.12506
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65586
hsa-miR-4769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7922
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.35228
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1917
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-200c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02855
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905225
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44693
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.70345
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
External encapsulating structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45587
POLR2J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66897
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.8341
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844488
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.458315
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.221884
chr12_80249997_G_A_b38	GTEx eQTL 2025	1.0	1.83061
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	77.7562
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Autosomal recessive nonsyndromic deafness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8107
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34643
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01485
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
Autosomal dominant nonsyndromic deafness 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Autosomal recessive nonsyndromic deafness 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3501
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01319
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.217
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1347
Tricellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17159
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56813
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1284
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.39725
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
POU3F2	ChEA Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39572
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4008
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Tadpole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.441
Enlarged vestibular aqueduct	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
HS683	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8581
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.853
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04361
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03574
Clonidine (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.017583
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98122
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18314
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3516
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32127
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905109
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47144
MTARC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38175
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992985
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878558
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCPAP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63656
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06297
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88516
production	GeneRIF Biological Term Annotations	1.0	null
Perturb_14212_KO_Sp8/Sp8_SRP095936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
synapse-associated extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33156
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85821
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870624
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.449576
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SBC5	CCLE Cell Line Gene Expression Profiles	1.0	1.43132
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90131
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0838
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5626
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37138
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.956
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.052036
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
SLC7A6OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1276
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905451
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.338
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5941_KD_PHB_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.41956
hsa-miR-4738-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Vascular endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03688
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69242
TM31	CCLE Cell Line Gene Expression Profiles	1.0	1.41011
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971749
GTEX-OXRL-0726-SM-3NM9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828221
Perturb_2938_OE_IL34_SRP396780	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17479
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841694
Goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00945
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
structures	GeneRIF Biological Term Annotations	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83239
Perturb_5976_KD_TRA2B_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.03003
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4563
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.88516
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49229
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15302
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944547
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4855
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7299
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0056
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.64463
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22265
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04224
hsa-miR-200b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93308
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46733
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.8589
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
Serous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
hsa-miR-4703-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NCI-H1355	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Excretory canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
ESRRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20936
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843435
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837237
muscular atrophy	GWASdb SNP-Disease Associations	1.0	0.79774
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95247
JUN_KO_GDS4205_294_mouse_B lymphoid cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7773
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.7069
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48687
Perturb_6250_KO_Ago2_SRP041835	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hereditary spherocytosis type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7001
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
External ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75551
HDAC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86582
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35855
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937487
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.48256
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82962
Perturb_5912_KD_GLTSCR2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.4006
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945766
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1647
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endothelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7907
COV434	CCLE Cell Line Gene Expression Profiles	1.0	2.65494
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6997
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	6.43889
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74786
hsa-miR-1278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969